>gi|115936791|ref|XP_001194137.	Strongylocentrotus purpuratus
MALSTAVKEGDLVKTRSILEDETGDTKLVMLCSVDPDGKTPLHIASEEG-HIDLEGHLDV
VDCLVNAGA-------DVNKAAKNGSTSLD----QASERGAD--VKKATQTGMTLLHAAS
SEGEVDVVKCLISKGANLNSVDNVGCTSLYIASQEGHLD---------------------
VVEYLANAGGDVNKVSHDGYAPLAIALRYNQHDIAQLLMAKEADLGLTDTGHITLLNAST
NGYIDAVKYIIRKGVDVNTGDGDGFT-SLYHASLNGHL--DVVECLVNAGAYVKTTSAED
GRTPLYAASSEGAVDVVKC-----LISKGANLNSVNNVGCTSLYIASQEGHLDVVECLAN
AGGDVNIAAEDGMTPLYAASSKGAINSVNCLISKGANLNAVDKVGCTSLYIASQEGHLDV
VEYLANAGGDVNIAAE--DGMT-PLYAASSEGAADVVKCLISKGANLDSVDNKG---ETP
LLIASQEG---HLD-VVECLANAGGDVNIAAEKGRTP---------LYAASYKGAVNIVK
---CLISKGANLNSVDNVGCTSLYIASQEGHLDVVEYLANAGGDVNKVSHDGWTPLHAAS
SE----------------GSVDVVK--CLISKGANLNSVDNYGETPL-------------
---------------YIASRKGHLDVVEC---------LAN----AGGD---------VN
IAA---------------------------------------------------------
------------------------------------------------------------
----------------------------EDGMTPLYAAS---------------------
---------------------------SEGAVDVVKCL------------ISKVANLNSV
DNEGDTPLIVASQEGH-----------LDVVECLVNAGADVNKAAKNGMTPLYAASNKGA
VHVVKCLISKGGSPNSVDDVGYTPLSIASFQGHFDVVECLVNAGADVNKATKNGLTTLYT
ASLKGHVDIVKYLISKGANPNSSYLDVYTTLSVASQAGHLNVVECLM-------------
------NAGADVNYAAKNGTTPLYAASSK-GEVDVVKSLISKGANLDLVDN---------
------------------------------DGETPLYIASCKGHLDVVECLVNAGAGVNK
-----AAKNGMT-------PLYAASSKGEVDVVKCLISKGA------NPNSV----GNDG
ETPLYIASR-----KGHL--NVVEC--LLNAGAD------INKAAKNGMTPLYAASNKGE
--VDVVKCLISKGADLNLVDYDDG-TPL--YIASQEGHLDVVECLANAG-ADVDKTAKNS
MTIHKAASKNSLGSMLMY--------RLYECANLKWLYQDGETPLYIASRKGH-------
-----LNVVECLINA---GADVDKAAKTGM----------------TPLYAASSKGAVDV
VKC----------------------------------LISEGADLNLYDN----------
----------------------------ECKTPLYIACQKGHLDVVECLA---S-EGGFI
NIESEDGRTPLY------------------------------------------------
-----AASSEGAVDVVKCLISEG-A-DLNLVDYDGETPLYIASFKGHLDVVECLLNAGGD
VN---------------------IVSEDGRTPLYAASSE-GADVNKAAKNGKT------P
LFAASSN---------GAVDIVNYLISQGANPNTVANDGYSPLHVATQKGHFDVVESLVN
AGAD------VKKPATDGDL-PLEAASRGGYL----------DIIKYLITKGADIETRCI
ISTSYRQCWSNTNSPCYCKRANIND--
>gi|73998369|ref|XP_862878.1|	Canis familiaris
------------------------MESCYDPGLDGMIE---------YD-DFKFDPCI--
----AEPKEP------APETADGPYLVIVE----QPKQRGFR--FR--------------
-----------------------------YGCEGPSHGG---------------------
----LPGAS---SEKGRKTYPTVKIC----------------------------------
-NYEGPAKIEVDL-----VTHSDP-P-RAHAHSLVGKQCSELGVCAVSVGPKDMTAQFNN
--LGVLHVTKKNMMEIMIQ-----KLQR--Q--------RLRSRPQGL------------
-------TEAE----------RRELEQEAKELKKVMDLSIV---------------RLRF
SAFLRASDGSFSLPLK--PVISQPIHDSKSPGASNLKISRMDKTAGSVR-GGDE---VYL
LCDKVQKD---DIE-VRFYEDDENG---WQAFGDFSPTDVHKQYAIVFRTPPYHKMKIER
PVTVFLQLKRKRGGDVSDSKQFTYYPLVEDKEEVQRKRRKALPTFSQH-FGG-----GSH
MG----------------GGSGGSAGGYGGAGGGARPVSAGGS--LG-------------
---------------F-------FPSLAY---------SPYPT--GSAP-----------
------------------------------------------------------------
------------------------------------------------------------
----------------------------LGCYPGGGGGA---------------------
---------------------------QMAAGAPGVDA------------GEEAAEPSAS
P----------LTPQR-----------EPQAPEL----------------------LQRG
TYN---------------------------------------------------------
------------------------------------ARLFGLAQRSA-------------
------RA--------------LLDYGVT-ADARALLAGQ--RHLLTAQDE---------
------------------------------NGDTPLHLAIIHGQTSVIEQIAHVIYHARH
-LGVVNLTNHLH-----QTPLHLAVITGQTSVVSFLLQVGA------DPALL----DRHG
DSAVHLALR-----AGTSAPDLLRA--LLRSGVPTMPQL-LHMPDFEGLYPVHLAVRARS
--PECLDLLVDSGAEVEAAERQGGRTAL--HLATEMEELGLVTHLVTKLRANVNART---
-----------------F---------------------AGNTPLHLAAGLGS-------
-----PTLTRLLLKA---GADIHAENEEPL------------CPLPSPPTSGSDSDSEGP
ERD------------------------------------ARGSS----------------
----------------------------RGHTPLDLTRSTKVKTLLLNAA---Q-DTMAP
PLTPPSPAGPDL------------------------------------------------
-----PLEDAVLQNLEHLLDGPG-A-QGS------WAEL--AERLGLRSLVDTY------
-R---------------------KTASPSGSLLRSYKLA-GGDLA-------G------L
LCALSDM---------GLEEGVRLLRGP--------------------------------
EARD--K---LPSTEVKEDS-AYGSQSVEQE------------------AEKLG------
-SPPEPPGGLCHGHPQPQVH-------
>gi|157106389|ref|XP_001649301.	Aedes aegypti
--------------------------------------TP-LHTAAGKG-NIEMVKLL--
----IDHNA-------NIDTKDDEGCTPLH----YASRNGNLEMVK--------------
-----------------------------LLIDNRANV----------------------
------------DTTQNEGWTPLHYA----------------------------------
-SQNGHIDVVKLL-----IDNRAN-V----------DTTQNEGCTPLHKAAENGHLDVVK
-----LLIDNKANVDT--------------A--------QSEGWTP--------------
----------------------------LHYASRNGNLELV---------------KLLI
DNRANVDTAQY-------EGWTPLHYASRNGQLDVVKLLIDNRANVDTT-QNEG---CTP
LHYASQNG---NLELVKLLIDNRAN-VDTAQYEGWTP---------LHYASQNGQLDVVK
---LLIDNRANVDTTQNEGCTPLHYASRNGNLELVKLLIDNRANVDTAQYEGWTPLHYAS
RN----------------GQLDVVK--LLIDNRANVDTTQNEGCTPL-------------
---------------------------------------HYASRNGNLE---------LV
KLL---------------------------------------------------------
------------------------------------------------------------
----------------------------IDNRANVDTAQ---------------------
---------------------------YEGWTPLHYAS------------QNGQLDVVKL
LIDNRAN----VDTTQ-----------NEGCTPL-HYASRNGNLELVKLLIDNRANVDTA
QYEG--------------------------------------------------------
------------------------------------WTPLHYASRNA-------------
------NV----DTTQNEGCTPLHYASRN-GNLELVKLLIENRANVDTAQN---------
------------------------------EGWTPLHYSSQNGHLKVVKLLIENKANVDT
------TQNEGW------TPLHYAFQNGHLEVVKFLIDNGA------NVDTM----NTRG
STSFHIVSQ-----NGRL--VLVKL--LIDNRAN------VDTTDNEGWTPLHYASQNGH
--LEVVKFLIDNGANFDTKNTR-GSTSF--HIASKNGRLEVVKLLIDNG-ANVDTTN---
-----------------N---------------------EGWTPLHYASRNGH-------
-----LEVVKLLIDN---GANVDTKNARGS----------------TSFHIVSQNGRLEV
VKL----------------------------------LIDNRANVDTTDN----------
----------------------------EGWTPLHYASRNGHLEVVKLLI---D-NGANV
DTKNTRGSTSFH------------------------------------------------
-----IASKNGRLEVVKLLIDNG-A-NVDTTNNEGWTPLHYASRNGHLEVVKLL------
--------------------------------IDN-----GANVDTKNARGST------S
FHIVSQN---------GRLEVVKLLIDN--------------------------------
--------------GANVDT-TYNERWTLLH------------------DASLN------
----------GHLEVVKLSID------
>gi|34577122|ref|NP_003989.2|	Homo sapiens
----------------------MAEDDPY----LGRPEQM-FHLDPSLT-HTIFNPEV--
----FQPQM-------ALPTADGPYLQILE----QPKQRGFR--FR--------------
-----------------------------YVCEGPSHGG---------------------
----LPGAS---SEKNKKSYPQVKIC----------------------------------
-NYVGPAKVIVQL-----VTNGKN-I-HLHAHSLVGKHC-EDGICTVTAGPKDMVVGFAN
--LGILHVTKKKVFETLEA-----RMTE--A--------CIRGYNPGLLVHPDLAYLQAE
GGGDRQLGDRE----------KELIRQAALQQTKEMDLSVV---------------RLMF
TAFLPDSTGSFTRRLE--PVVSDAIYDSKAPNASNLKIVRMDRTAGCVT-GGEE---IYL
LCDKVQKD---DIQ-IRFYEEEENG-GVWEGFGDFSPTDVHRQFAIVFKTPKYKDINITK
PASVFVQLRRKSDLETSEPKPFLYYPEIKDKEEVQRKRQKLMPNFSDS-FGG-----GSG
AG----------------AG-GGGM--FGSGGGGGG-TGST-G--PG-------------
---------------YS------FPHYGF---------PTY----GGIT---------FH
PGT---------------------------------------------------------
------------------------------------------------------------
----------------------------TKSNAGMKHGT---------------------
---------------------------MDTESKKDPEG------------CDKSDDKNTV
NLFGKV-----IETTE-----------QDQEPSEATVGNGEVTLTYATGTKEESAGVQDN
LFL---------------------------------------------------------
------------------------------------EKAMQLAKRHA-------------
------NA--------------LFDYAVT-GDVKMLLAVQ--RHLTAVQDE---------
------------------------------NGDSVLHLAIIHLHSQLVRDLLEVTSGLIS
-DDIINMRNDLY-----QTPLHLAVITKQEDVVEDLLRAGA------DLSLL----DRLG
NSVLHLAAK-----EGHD--KVLSI--LLKH--KKAALL-LDHPNGDGLNAIHLAMMSNS
--LPCLLLLVAAGADVNAQEQKSGRTAL--HLAVEHDNISLAGCLLLEGDAHVDSTT---
-----------------Y---------------------DGTTPLHIAAGRGS-------
-----TRLAALLKAA---GADPLVENFEPL----------------Y-----DLDDSWEN
AGE------------------------------------DEGVV----------------
----------------------------PGTTPLDMATSWQVFDILNGKP---Y-EPEFT
SDDLLA-QGDMK------------------------------------------------
-----QLAEDVKLQLYKLLEIPD-P-DKN------WATL--AQKLGLGILNNAF------
-R---------------------LSPAPSKTLMDNYEVS-GGTVR-------E------L
VEALRQM---------GYTEAIEVIQAA-----------SSPVKTTSQAHSLPLSPASTR
QQID--E---LRDSDSVCDS-GVETSFRKLSF-----------------TESLT-SGASL
LTLNKMPHDYGQEGPLEGKI-------
>gi|52345970|ref|NP_001005032.1	Xenopus tropicalis
-----------------MSALKIENFDPY--SCNGIEE---------SN-GIGYSSSL--
----LDTRVL------GQDMANVAFLSIIE----QPKQRGFR--FR--------------
-----------------------------YVCEGPSHGG---------------------
----LPGAS---SEKGKKTYPTVKIF----------------------------------
-NYVGMARIEVDL-----VTHIDP-P-RVHAHSLVGKHSNETGNCVVTVGPEDMTAQFNN
--LGIVHVTKKSQTEILKE-----KMKR--Q--------ILRHTGRNL------------
------LTEAE----------ERRIEQEVKELKKVTDLSIV---------------RLRF
TAYLPDSNGAYTLGLP--PVISDPIHDSKSPGASNLRISRMDKTAGSVK-GGDE---VYL
LCDKVQKD---DIE-VRFYEDDENG---WQSFGDFAPTDVHKQYAIVFRTPPYHTQKIDR
PVTVFLQLKRKKGGDVSDSKQFTYYPLEQDKEEVDRKRRKDLPTFNNHFFGG-----GSP
MG----------------GAGGGSS--FGQGGGGSN---------IN-------------
---------------YP------YPGMQT---------AFYMSSPAGGG---------YH
SSG---------------------------------------------------------
------------------------------------------------------------
----------------------------HMMKHCSAANS---------------------
---------------------------SEKNQAPSINI------------KKEGEEASAC
SQQARS-----TSAQK-----------ETQCQMI---------------------MHQAN
LCN---------------------------------------------------------
------------------------------------MRMLSLTQRTS-------------
------RA--------------LLDYAIT-ADPRMLLAVQ--RHLIATQDE---------
------------------------------NGDTPLHLAVIHGQPSVIEQLVQVIISIPN
-QQILNMSNHLQ-----QTPLHLGVITKQYSVVAFLLKAGA------DPTIL----DRYG
NSVLHLAVQ-----AEDD--KMLSV--LLKYPSVGQKDL-LNMPDYHGLCPVHWSVKMKN
--EKCLELLVKAGANVNSPERKSGKSPL--HIAVEMDNLNMAIFLVKKSHADINAKT---
-----------------Y---------------------GGNTPLHLAASRGS-------
-----PMLTKMLVNE---GANVLSENDEPV----------------NKLPSCNSDTSESD
SDV------------------------------------QMDTDSDHHGGSDTDSSTAVD
SDCEHSAEEMHSKEQRGIRPHCAVKRRYPGHTALDLTKSQKVRDILSKHT---P-GSASW
KRREPEPVNVL-------------------------------------------------
-----ALETNTVQRLEKLLNEGQ-T-GAD------WTEL--ASRLRLQSLVETY------
-R---------------------NTSSPTESLLRSYELA-GGSLT-------E------L
INTLQSM---------GLNKGVELLCKS-------------------------------E
TYAK--H---QSPAEGKNDS-AYESQSMEVDQ-----------------SSAEL------
---------SPTTEPAIGQ--------
>gi|156447583|gb|ABU63584.1|	Sus scrofa
----------------------MAEDDPY----LGGHDQM-FHLDP-LN-HTIFNPEL--
----FQPEM-------PLPTADGPYLQILE----QPKQRGFR--FR--------------
-----------------------------YVCEGPSHGG---------------------
----LPGAS---SEKNKKSYPQVKIC----------------------------------
-NYVGPAKVIVQL-----VTNGKN-I-HLHAHSLVGKHC-EDGICTVTAGPKDMVVGFAN
--LGILHVTKKKVFETLEA-----RMTE--A--------CIRGYNPGLLVHPDLAYLQAE
GGGDRQLTDRE----------KEIIRQAALQQTKEMDLSVV---------------RLMF
TAFLPDSTGSFTRRLE--PVVSDAIYDSKAPNASNLKIVRMDRTAGCVT-GGEE---IYL
LCDKVQKD---DIQ-IRFYEEEENG-GIWEGFGDFSPTDVHRQFAIVFKTPKYKDVNITK
PASVFVQLRRKSDLETSEPKPFLYYPEIKDKEEVQRKRQKLMPNFSDS-FGG-----GSG
AG----------------AG-GGGM--FGSGGGGGG-AGST-G--PG-------------
---------------YG------FPHYGF---------PTY----GGIT---------FH
AGT---------------------------------------------------------
------------------------------------------------------------
----------------------------TKSNAGMKHGT---------------------
---------------------------VDTPSKNDPED------------CDKSDDREAV
NLSGKV-----TETTE-----------QDKESSN---GEDEVHLTYSVGVKEENYRFQDN
LFL---------------------------------------------------------
------------------------------------EKAMQLAKQHA-------------
------NA--------------LFDYAVT-GDVKMLLAVQ--RHLTAVQDE---------
------------------------------NGDSVLHLAIIHLHAQLVRDLLEVTSGLIS
-DEIINMRNDLY-----QTPLHLAVITKQEAVVEDLLRAGA------DLSLL----DRLG
NSVLHLAAK-----EGHD--KILSI--LLKH--KKAALL-INHPNGEGLNAIHVAMMSNS
--LPCLLLLMAAGADVNAQERKSGRTAL--HLAVELDNISLAGCLLLEGDAHVDSTT---
-----------------Y---------------------DGTTPLHIAAGRGS-------
-----TRLAALLKAA---GADPLVENFEPL----------------Y-----DLDDSWDE
DGE------------------------------------DEGVV----------------
----------------------------PGTTPLDMATNWQVFDILNGKP---Y-EPEFT
SDDLLA-QGDMK------------------------------------------------
-----QLTEDTKLQLYKLLEIPD-P-DKN------WATL--AQKLGLGILNNAF------
-R---------------------LSAAPSKTLMDNYEVS-GGTIK-------E------L
VEALRQM---------GYTEAIDVIQAA---FCTSGTAATSPVKTTSQAHSLPFSPASTR
QQID--E---LRD-DSICDS-GVETSFRKLSF-----------------TESLT-SSSSL
LTLNKVPHDFGQEGPLEGKI-------
>gi|125968525|gb|ABN58794.1|	Siniperca chuatsi
----------------------MAGEDHY---------------HQIFD-NIMLEPSW--
----DFPHFPAMSQTTSLQTVDGPFLQIVE----QPKQRGFR--FR--------------
-----------------------------YGCEGPSHGG---------------------
----LPGAS---SEKNRKTYPTVKIS----------------------------------
-NYQGPSRVVVQL-----VTALTPLP-QLHAHSLVGKQC-DKGICIADLQPKDSNISFPD
--LGILHVTKKNVAKTLEE-----RMIE--A--------YRMGYNCGVSIHPEIDAVQGE
VRVPRDLTEHQ----------RSVISSVAALQAKEMDLSVV---------------RLMF
TAFLPDSDGGFSRRLE--PVVSEPIYDSKAPNASNLKIVRMDRTAGCVT-GGEE---VYL
LCDKVQKD---DIQ-VRFYEEDDSG-LTWEALGDFSPTDVHRQFAIVFKTPKYRDQNLQK
PTSVFVQLKRKSDNETSEPKPFTYHPQIIDKEEVQRKRQKTLPNFQD--FSG----HGGG
GG----------------GG-GGGL--YRGGGGGGGPATGG-G--PG-------------
---------------SAGGGGAYFQGFTT---------YNY----GGGG---------FS
TG----------------------------------------------------------
------------------------------------------------------------
------------------------------YSAGLGGGG---------------------
---------------------------IKHASQGDAAD------------DSDPDDDSG-
--SGVV-----LRASA-----------QPGG------------LEVGERTEEGGVSVEPE
PHG---------------------------------------------------------
------------------------------------DERLVIS-RQL-------------
------EA--------------LFQYSVT-GDSAYLLALQPPRSTHRTRTE---------
------------------------------TPGSIWRFST----ASRALSLTQVASALPG
-QEVLNMRNHLY-----QTPLHLAVITQQREAVEALLLAGA------DPTLT----DRHG
NTVLHLASQ-----LEGG--GMVQF--LLQH--RELREL-LYHTNTAGLCAIHLAVLANQ
--LSSLRELLEGGANVEAQERSCGRTAL--HLATEADNVSLAGCLLLEGNANVDCCT---
-----------------F---------------------NGSTPLHIAAGRGS-------
-----IRLTALLMAA---GADPHKENFEPL----------------FFKEEECCDEERED
EDE------------------------------------DEGYI----------------
----------------------------PGTTPLNMAATTQVLELLNGKQ---Y-EPTSP
PRASIPPQGDLA------------------------------------------------
-----SLDTEVKQEVCRALESEG-C----------WENL--AHSLGLGILKVAF------
-R---------------------LSPSPAKTLLDSYEVS-GGTVR-------D------L
LAGLRSV---------GECRALSVLEEA-------------------------------L
RHLD--DMDAQTVNETRGESPCAQVQDLKRTF-----------------GSTAG------
---------CATAGWSSPRR-------
>gi|115497302|ref|NP_001069877.	Bos taurus
----------------------MAEDDPY----LGGREQM-FHLDP-LN-HTMFSPEL--
----FQPEM-------PLPTADGPYLQILE----QPKQRGFR--FR--------------
-----------------------------YVCEGPSHGG---------------------
----LPGAS---SEKNKKSYPQVKIC----------------------------------
-NYVGPAKVIVQL-----VTNGKN-I-HLHAHSLVGKHC-EDGVCTVTAGPKDMVVGFAN
--LGILHVTKKKVFETLEA-----RMTD--A--------CIRGYNPGLLVHPDLAYLQAE
GGGDRQLTDRE----------KEIIRQAALQQTKEMDLSVV---------------RLMF
TAFLPDSTGSFTRRLE--PVVSDAIYDSKAPNASNLKIVRMDRTAGCVT-GGEE---IYL
LCDKVQKD---DIQ-IRFYEEEENG-GIWEGFGDFSPTDVHRQFAIVFKTPKYKDVNITK
PASVFVQLRRKSDLETSEPKPFLYYPEIKDKEEVQRKRQKLMPNFSDS-FGG-----GSG
AG----------------AG-GGGM--FGSGGGGGG-AGST-G--PG-------------
---------------YG------FPHYGF---------PTY----GGIT---------FH
TGT---------------------------------------------------------
------------------------------------------------------------
----------------------------TKSNAGMKHGT---------------------
---------------------------IDTPSKNDPES------------CGKSDDREVV
NLSEQV-----TETTE-----------QDGGSCK---RGTAANLTCSVGVKEENRSFQDN
LFL---------------------------------------------------------
------------------------------------EKAMQLAKQHA-------------
------NA--------------LFDYAVT-GDVKMLLAVQ--RHLTAVQDE---------
------------------------------NGDSVLHLAIIHLHNQLVRDLLEVTSGLIS
-DEIINMRNDLY-----QTPLHLAVITRQEAVVEDLLRAGA------DLSLL----DRLG
NSVLHLAAK-----EGHD--KILGI--LLKH--KKAAQL-IDHPNGEGLNAIHVAMMSNS
--LPCLLLLMAAGADVNAQERKSGRTAL--HLAVEHDNVSLAGCLXLEGDAHVDSTT---
-----------------Y---------------------DGTTPLHIAAGRGS-------
-----TRLAALLKAA---GADPLVENFEPL----------------Y-----DLDDSWDE
DGE------------------------------------DEGVV----------------
----------------------------PGTTPLDMASSWQVFDILNGKP---Y-EPEFT
SDDLLA-QGDMK------------------------------------------------
-----QLTEDAKLQLYKLLEIPD-P-DKN------WATL--AQKLGLGILNNAF------
-R---------------------LSPAPSKTLMDNYEVS-GGTIK-------E------L
VEALRQM---------GYTEAIDVIQAA---FCTADT---SPAKTTSQAHSLPFAPASTR
PQID--E---LRD-DSICDS-GVETSFRKLSF-----------------TESLT-SGTSL
LTLNKVPHDYGQEGPIEGKI-------
>gi|126331024|ref|XP_001368747.	Monodelphis domestica
------------------------------------------------M-HGTAEPTL--
----YNVSAIACY---DLDNADGPYLQILE----QPKQRGFR--FR--------------
-----------------------------YVCEGPSHGG---------------------
----LPGAS---SEKNKKSYPQVKIC----------------------------------
-NYVGPAKVIVQL-----VTNGKH-V-HLHAHSLVGKHC-EDGICTVTAGPKDMVVGFAN
--LGILHVTKKKVYETLEA-----RMTD--A--------CIRGYNPGLLVHPELNYLQPE
GGGERQLTDRE----------KEIIRQAAVQQTKEMDLSVV---------------RLMF
TAFLPDSTGSFTRRLE--PVVSDAIYDSKAPNASNLKIVRMDRTAGCVT-GGEE---IYL
LCDKVQKD---DIQ-IRFYEEEENG-GFWEGFGDFSPTDVHRQFAIVFKTPKYKDVNITK
PASVFVQLRRKSDLETSEPKPFLYYPEIKDKEEVQRKRQKLMPNFSDS-FGG-----GSG
AG----------------AG-GGGM--YGGGGGGGG-SASA-G--PG-------------
---------------YG------FAPYGF----------SY----AGIP---------FH
PGT---------------------------------------------------------
------------------------------------------------------------
----------------------------TKSNAGMKHGT---------------------
---------------------------LDSSSVQGHAG------------CDESDDRSSA
ELSGKI-----LKTTE-----------QDDKPRV--TGRDEITLTCTV-VEEEDCRLQGD
PFL---------------------------------------------------------
------------------------------------EKAMQLAKRHA-------------
------SA--------------LFDYAVT-GDVKVLLAVQ--RHLTAVQDD---------
------------------------------NGDNVLHLAIIHLHAELVRNLLEVISGLLS
-DDIINMRNDLY-----QTPLHLAVITKQEDVVEDLLRAGA------DVSLL----DRLG
NSALHLAAK-----EGDD--KILNI--LLKH--KKILPL-IDHPNGEGLNAIHLAMLINS
--MPCLRLMIAAGADVNAQEQTSGRTAL--HLAVEQENVSLAGCLLLEGDAFVDSTT---
-----------------Y---------------------DGTTPLHIAAGRGS-------
-----TKLAALLKAA---GADPLLENFEPL----------------Y-----DLDDVWDQ
DGE------------------------------------DEGVV----------------
----------------------------PGTTPLDMAANSQVYDILNGKP---Y-QSEST
SSDLLA-QGDMK------------------------------------------------
-----QLDEEAKLQLYKLLEMPD-P-DKN------WSTL--AQKLGLGILNNAF------
-R---------------------LSPAPSKTLMDNYEVS-GGTIR-------E------L
VDALRQM---------GYTEAIEVIQKA---FSASVNPSEIKEQPTEQIYSLPPSPSCIR
QQLG--DICKLQDNESVCDS-GVETSFRKLSF-----------------TESLT-STGAL
ITLNKMPCDYGQETSIEGKV-------
>gi|148231358|ref|NP_001087808.	Xenopus laevis
-----------------MAQNMYDIDDAH--------LETFLRINPLFQ-EPMYMP----
----SEP---------HLRNAEGPYIEITE----QPKQRGFR--FR--------------
-----------------------------YVCEGPSHGG---------------------
----LPGAS---SEKNRKSYPQIKIH----------------------------------
-NYVGQVKVVVQL-----ITNSKD-I-RLHAHSLVGKNC-EDGICSLTVGPKDTIVGFPN
--LGILHVTKKKVIEILEA-----RMTD--A--------FKKGHNAALLVHPELNYTNSE
---DRPLNERE----------KEIIRQAATQQSKDIDLSVV---------------RLMF
TAFLLDSEGRFTRSLE--PVLSVPIFDSKAPNASNLKIVRMDRTAGCVT-GGEE---VYL
LCDKVQKD---DIQ-VRFYEEDENG-GYWEGFGDFSPTDVHRQFAIVFKTPKYKDVNITK
AASVFVQLRRKSDYETSEPKPFLYYPEIKDKEEVQRKRQKLMPNFSDG-YGG----SGAG
SG----------------GGVGGGL--YGGGGGAGG---SA-G--GG-------------
---------------YG------FSSFSY---------NNY----GGLN---------FH
GGP---------------------------------------------------------
------------------------------------------------------------
----------------------------MNSGPCMKHES---------------------
---------------------------KSRCEEANQKH------------GETTNTQDAS
NEGSCL-----CIKTA-----------QEKEERE----------TAPAREEGEFCKLHDC
NFL---------------------------------------------------------
------------------------------------SKAMQLAKRHA-------------
------AS--------------LFDYAVT-GDVRMLLIVQ--RHLASVQDE---------
------------------------------NGDNILHLSIIHLHSALVRIFLDITQGVVC
-DDIINVRNDLY-----QAPLHLAVITQQVDTVQDILEAGG------DPLLL----DRDG
NSVLHLACK-----EGDA--LTLSL--LLKH--KKTLEI-INLPNNDGLNPIHVAVLANC
--MSCLRLLISAGADVNAQEQKSGKNAL--HLAVEQENISLAGCLLLEGDACVDSTT---
-----------------Y---------------------DGNTPLHIAVGRSS-------
-----TKLTALLKAA---GADSFIESFEPL----------------Y-----SFEDTQDE
DDV------------------------------------DEGIV----------------
----------------------------PGTKPLDIANCNEVLEILNGMP---Y-RSEVA
PEDSLT-QGDMK------------------------------------------------
-----NLSKEVNQKLYNLLESQD-L-DKN------WATL--AQKLGLGMLNNAF------
-R---------------------LSPLPSKTLLDNFEVS-GGTIR-------E------L
LDALKRM---------HYTEAIEAIEQS---------QGILTLSGATTSSEAPIAAQRRD
SSMDDISYLKHQETESTCDS-GVETSFQKLSI-----------------SYSEF-LKETE
GICTELPQE--PDCPLICSK-------
>gi|50979190|ref|NP_001003344.1	Canis lupus
----------------------MAEDDTY----LGAHEQM-FHLDP-LT-HTIFNPEL--
----FQPEM-------PLPTADGPYLQILE----QPKQRGFR--FR--------------
-----------------------------YVCEGPSHGG---------------------
----LPGAS---SEKNKKSYPQVKIC----------------------------------
-NYVGPAKVIVQL-----VTNGKN-I-HLHAHSLVGKHC-EDGICTVTAGPKDMVVGFAN
--LGILHVTKKKVFETLEA-----RMTE--A--------CTKGYNPGLLVHPDLAYLQAE
GGGDRQLTDRE----------KEIIRQAALQQTKEMDLSVV---------------RLMF
TAFLPDSTGSFTRRLE--PVVSDAIYDSKAPNASNLKIVRMDRTAGCVT-GGEE---IYL
LCDKVQKD---DIQ-IRFYEEEGNG-GIWGGFGDFSPTDVHRQFAIVFKTPKYKDVNITK
PTSVFVQLRRKSDLETSEPKPFLYYPEIKDKEEVQRKRQKLMPNFSDS-FGG-----GSG
AG----------------AG-GGGM--FGSGGGGGG-AGST-G--PG-------------
---------------YG------FPHYGF---------PTY----GGIT---------FH
PGT---------------------------------------------------------
------------------------------------------------------------
----------------------------TKSNAGMKNGT---------------------
---------------------------IDTPSKNDSEG------------CGKNVDREAV
NLSGKV-----TEPTE-----------QDKESSM---GVDEVTLTYTVGIKEENSRFQDN
LFL---------------------------------------------------------
------------------------------------EKAMQLAKRHA-------------
------NA--------------LFDYAVT-GDVKMLLAVQ--RHLTAVQDG---------
------------------------------NGDSVLHLAIIHLHAQLVRDLLEVTSGLIS
-DDIINMRNDLY-----QTPLHLAVITKQEAVVDDLLRAGA------DLSLL----DRLG
NSVLHLAAK-----EGQD--KILSI--LLKH--KKAALL-MDHPNGEGLNAIHIAVMSNS
--MPCLLLLVAAGADVNAQERKSGRTAL--HLAVEHDNISLAGCLLLEGDAHVDSTT---
-----------------Y---------------------DGTTPLHIAAGRGS-------
-----TRLAALLKAA---GADPLVENFEPL----------------Y-----DLDDSWEK
DGE------------------------------------DEGVV----------------
----------------------------PGTTPLDMATNWQVFDILNGKP---Y-EPEFT
SDDLLA-QGDMK------------------------------------------------
-----QLTEDAKLQLYKLLETPD-P-DKN------WATL--AQKLGQGILNNAF------
-R---------------------LSPAPSKTLMDNYEVS-GGTIK-------E------L
VEALRQM---------GYTEAIEVIQAA---FCAPETAAPSPGKGAPQTLSLPLSSASTR
SPVD--E---VRD-DSICDS-GVETSFRRLSF-----------------TESLT-SGSSL
LTLNKAPHEYGQEGPIEGKI-------
>gi|18204817|gb|AAH21490.1|	Mus musculus
HASAHASVILILELVAGGELFDFLAEKES----LTEEEAT-EFLKQILS-GVYYLHSLQI
AHFDLKPENIML----LDRNVPKPRIKIIDFGLAHKIDFGNE--FK--------------
-----------------------------NIFGTPEFVAPEIVNYEPLGLEADMWSIGVI
TYILLSGASPFLGDTKQETLANVSAV----------------------------------
-NYDFEEEFFRNT-----STLAKDFIRRLLVKDPKKRMTIQDSLQHPWIKPKDTQQALSR
-KASAVNMEKFKKFAARKKWKQSVRLIS--L--------CQR-LSRSFLSRSNMSVARSD
-----DTLDEE----------DSFVMKAIIHAINDDNVPGL-------------------
-QHLLGSLSSYDVNQPNKHGTPPLLIAAGCGNIQMLQLLIKRGSRIDVQ-DKGG---SNA
IYWASRHG---HVDTLKFLNENKCP-LDVKDKSGETALHV---------AARYGHADV--
-VQLLCSFGSNPDFQDKEEETPLHCAAWHGYYSVAKALCEVGCNVNIKNREGETPLLTAS
AR----------------GYHDIVE--CLAEHGADLNASDKDGHIAL-------------
--------HLAVRRCQMEVIKTLLGHGSF---------VDFQDRHGNTP---------LH
VACKDGSAPIVVALCEASCNLDISNKYGRTPLHLAANNGILDVVR---------------
------------------------------------------------------------
----------------------------YLCLMGANVEA---------------------
---------------------------LTSDGKTAEDL------------AKAEQHEHVA
GLLARL-----RKDTHRGLFIQQLRPTQNLQPRIKLKLFGHSGSGKSTLVESLKCGLLRS
FFR---------------------------------------------------------
------------------------------------RRRPRLSSTNSTRFPPSPLAAKPT
VSVSINNLYPGCENVSVRSRSMMFEPGLTKGMLEVFVAPS--HHLHCSTDDQSTKAIDIQ
NAYLNGVGDFSVWEFSGNPVYFCCYDYFAANDPTSIHIIVFSLEEPYEIQLNQVIFWLSF
LKSLVPVEEPIAFGGKLKNPLRVVLVATHADIMNIPRPAGGEFGYDKDTSLLKEIRNRFG
NDL-HVSNKLFVLDAGASGSKDIKV--LRNHLQE------IRSQIVSGCSPMTHLCEKII
STLPSWRKLNGPNQLMSLQQFVYDVQDQLNPLASEDDLRRIAQQLHSTGEINIMQSE---
-----------------TVQDVLLLDPRWLCTNVLGKLLSVETPRALHHYRGRYT-----
----MEDIQRLVPDS---DVEELLQILDAMDICARDLSSGTMVDIPALIKTDSLQRSWAD
EEDEVMVYGGVRIVPVEHLTPFPCGIFHKVQVNLCRWIHQQSAEGDADIRLWVSGCRIAN
RGAELLVLLVNHGQGIEVQVRGLETEKIKCCLLLDSVCSTIETVMATTLPGLLTVKHYLS
PQQLREHHEPVMVYQPRDFFRAQTLKESSLTNTMGGYKESFSSITCFGCHDVYSQASLGM
DIHASDLSLLTRRKLSRLLDPPD-PMGKD------WCLL--AMNLGLPDMVAKHNVNNRA
SR--------------------DFLPSPVHALLQEWTSYPESTVG-------I------L
ISKLREL---------GRRDAADFLLKA----------------------------SSVF
KINL--DGNGQEAYASSCNS-GTSYNSISSVV-----------------SR---------
---------------------------
>gi|118790060|ref|XP_317997.3|	Anopheles gambiae
--------------------------------------MA-WLGIGALA-SGLAIQRL--
----LGGDVPPNK---VQEVKNESYINL------PVLQRNES--MR--------------
-----------------------------LFAPNPNSPD-----------------KKLV
YEIILERPH---SETINTSYSLYRATTQS----------------------------AAE
EKFEAFHQRLPEL-----VKIVRE-M-----YNINGLQ----KLC-------DVLIDNPS
--WSLAHVV---AFYNLTD-----YISN--P--------SIIDF----------------
------LDYAE----------YSEMMTPLQVAVKANNIEFV-------------------
KALIQSNQCNLEHLDK--NSNSVFHYAASTTKEMINMLTAKSTSNLNHC-NTDGYTPLHL
ACLADKPD---CVKALLLAGADTNK----MARGAGTS------YSKSIPSSNVADFLVSN
PNKLFTQDMKHGGT-------PLHWSSSREVLNSLIERG---CDVNLVNFNGQTPLHVMV
AR----------------DRLECVV--ALLAHDAEIDVVDNSGNTPL-------------
---------------HIAVEKKLIPIVQC---------LVV----FGAD---------F-
------------------------------------------------------------
------------------------------------------------------------
-----------------------------------NKPN---------------------
---------------------------KDGKTPRHLVG------------KDDSGSKDSM
ILYILHSVGAKRCPEK-----------GSKCPPGCAAGGTYNGIPPAQPETTEQREHIQQ
VLA---------------------------------------------------------
------------------------------------RTTTKSHRNSV-------------
------PS--------------LISNTIR-ATIPEERERPEVKTVDVSQER---------
------------------------------KGASMMD-ALLSMFMSKVEAASKPTSPTST
SSSLKECAGGSG-----QRTDSRPRSSCEAGASGESYNGRG------RLLCL----DGGG
IRGLVLAQ------------MLLEIENLAQTPIVHLFDW-IAGTSTGGILALALGCGKTM
KQCMCLYLRMKDQAFVGSRPYPSDQLET--VLKEQLGEFTVMSD-IKHPRLMVTGVM---
---------------------------------------ADRKPVNLHLFRNYEA-----
----ASDILSIVTPSNNRGQPPPPPSEQLV--------------WRAARATGAAPSYFRA
FGR----------------------------------FLDGGLI----------------
----------------------------ANNPTLDAMT--EIHELNAALHYIGR-ASEAV
PVSVVVSLGT--------------------------------------------------
-----GLTPVVDLKEIDVFRPDS-I----------WATA--KVAYGISTISTLL------
--------------------------------VDQATASDGRVVD-----RAR------A
WCSMIGV---------PYFRFNPQMSVD----------------------------IGMD
EKMD--E---PLINMLWEAK-AYMHSNRKQVI-----------------E---------L
INLLK----------------------
>gi|114595429|ref|XP_001168553.	Pan troglodytes
------------------------------------------------------------
--------M-------AL------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
--------DRE----------KELIRQAALQQTKEMDLSVV---------------RLMF
TAFLPDSTGSFTRRLE--PVVSDAIYDSKAPNASNLKIVRMDRTAGCVT-GGEE---IYL
LCDKVQKD---DIQ-IRFYEEEENG-GVWEGFGDFSPTDVHRQFAIVFKTPKYKDINITK
PASVFVQLRRKSDLETSEPKPFLYYPEIKDKEEVQRKRQKLMPNFSDS-FGG-----GSG
AG----------------AG-GGGM--FGSGGGGGG-TGST-G--PG-------------
---------------YS------FPHYGF---------PTY----GGIT---------FH
PGT---------------------------------------------------------
------------------------------------------------------------
----------------------------TKSNAGMKHGT---------------------
---------------------------MDTESKKDPEG------------CDKSDDKNTV
NLFGKV-----IETTE-----------QDQEPSEATVGNGEVTLTYATGTKEESAGVQDN
LFL---------------------------------------------------------
------------------------------------EKAMQLAKRHA-------------
------NA--------------LFDYAVT-GDVKMLLAVQ--RHLTAVQDE---------
------------------------------NGDSVLHLAIIHLHSQLVRDLLEVTSGLIS
-DDIINMRNDLY-----QTPLHLAVITKQEDVVEDLLRAGA------DLSLL----DRLG
NSVLHLAAK-----EGHD--KVLSI--LLKH--KKAALL-LDHPNGDGLNAIHLAMMSNS
--LPCLLLLVAAGADVNAQEQKSGRTAL--HLAVEHDNISLAGCLLLEGDAHVDSTT---
-----------------Y---------------------DGTTPLHIAAGRGS-------
-----TRLAALLKAA---GADPLVENFEPL----------------Y-----DLDDSWEN
AGE------------------------------------DEGVV----------------
----------------------------PGTTPLDMATSWQVFDILNGKP---Y-EPEFT
SDDLLA-QGDMK------------------------------------------------
-----QLAEDVKLQLYKLLEIPD-P-DKN------WATL--AQKLGLGILNNAF------
-R---------------------LSPAPSKTLMDNYEVS-GGTVR-------E------L
VEALRQM---------GYTEAIEVIQAA-----------SSPVKTTSQAHSLPLSPASTR
QQID--E---LRDSDSVCDS-GVETSFRKLSF-----------------TESLT-SGASL
LTLNKMPHDYGQEGPLEGKI-------
>gi|2130628|gb|AAB58343.1|	Gallus gallus
-MEATTATTARLNQPCADPGLKMAGEDPY---IMGVSDPQMFAMDQLMGMSTIFNNTG--
----YITSDL------PLRTADGPYLQIIE----QPKQRGFR--FR--------------
-----------------------------YVCEGPSHGG---------------------
----LPGAS---SEKNKKSYPQVKIC----------------------------------
-NYVGPAKVIVQL-----VTNGKY-V-HLHAHSLVGKFC-EDGVCTVNAGPKDMVVGFAN
--LGILHVTKKKVFETLET-----RMID--A--------CKKGYNPGLLVHPELGYLQAE
GCGDRQLTERE----------REIIRQAAVQQTKEMDLSVV---------------RLMF
TAFLPDSNGGFTRRLD--PVISDAIYDSKAPNASNLKIVRMDRTAGCVT-GGEE---IYL
LCDKVQKD---DIQ-IRFYEEDENG-GMWEGFGDFSPTDVHRQFAIVFKTPKYRDVNITK
PASVFVQLRRKSDLETSEPKPFLYYPEIKDKEEVQRKRQKLMPNFSDG-YGG-----GSG
AG-------------------GGGM--FGGGGGGAG---------SG-------------
---------------FS------YPSYGY---------SAF----GGMH---------FH
PGT---------------------------------------------------------
------------------------------------------------------------
----------------------------TKSNAGMKHEL---------------------
---------------------------SNSTVKKDEES------------SDKQSDKWDT
KHDVKV-----ETVEK-----------NECRTSGHNEEKEDASLCCKDEGNKPKCGCQDG
LFL---------------------------------------------------------
------------------------------------EKAMQLAKRHC-------------
------NR--------------LFDYAVT-GDVRMLLAVQ--RHLTAVQDD---------
------------------------------NGDNVLHLSIIHLHRELVKNLLEVMPDMNY
-NNIINMRNDLY-----QTPLHLAVITKQAEVVEDLLKAGA------NVNLL----DRHG
NSVLHLAAA-----EGDD--KILSL--LLKH--QKASSM-IDLSNGEGLSAIHMVVTANS
--LSCLKLLIAAGVDVNAQEQKSGRTAL--HLAVEQENVPLAGCLLLEGDADVDSTT---
-----------------Y---------------------DGTTPLHIAAGRGF-------
-----TKLAAVLKAA---GADPHVENFEPL----------------F-----DVEEDVKD
DDD------------------------------------DEGIV----------------
----------------------------PGTTPHDMAANWEVYDILNGKP---YIAAAAV
SEDLLS-QGPLR------------------------------------------------
-----ELNESSKQQLYKLLETPD-P-SKN------WSTL--AEKLGLGILNNAF------
-R---------------------LSPSPSKTLLDNYKIS-GGTVQ-------E------L
IAALTQM---------DHTEAIEVIQKA---LSSSQRQSHQEDNTIEAFPSLSPTSFAKE
ETGELYN-HKFQDPESTCDT-GVETSFRKLSF-----------------TYSDSLNSKSS
ITLSKMTLGYGRKAQCKAVIYLTR---
>gi|109075149|ref|XP_001109277.	Macaca mulatta
----------------------MAEDDPY----LGRPEQM-FHLDPSLT-HTIFNPEV--
----FQPQM-------ALPTADGPYLQILE----QPKQRGFR--FR--------------
-----------------------------YVCEGPSHGG---------------------
----LPGAS---SEKNKKSYPQVKIC----------------------------------
-NYVGPAKVIVQL-----VTNGKN-I-HLHAHSLVGKHC-EDGICTVTAGPKDMVVGFAN
--LGILHVTKKKVFETLEA-----RMTE--A--------CIRGYNPGLLVHPDLAYLQAE
GGGDRQLGDRE----------KELIRQAALQQTKEMDLSVV---------------RLMF
TAFLPDSTGSFTRRLE--PVVSDAIYDSKAPNASNLKIVRMDRTAGCVT-GGEE---IYL
LCDKVQKD---DIQ-IRFYEEEENG-GVWEGFGDFSPTDVHRQFAIVFKTPKYKDVNITK
PASVFVQLRRKSDLETSEPKPFLYYPEIKDKEEVQRKRQKLMPNFSDS-FGG-----GSG
AG----------------AG-GGGM--FGSGGGGGG-TGST-G--PG-------------
---------------YS------FPHYGF---------PTY----GGIT---------FH
PGT---------------------------------------------------------
------------------------------------------------------------
----------------------------TKSNAGMKHGT---------------------
---------------------------MDTESKKDSEG------------CDRSDDRNTV
NLFGKV-----IETTE-----------HNQEPSEATDGNGEVTLTYATRAKEESARVQDN
LFL---------------------------------------------------------
------------------------------------EKAMQLAKRHA-------------
------NA--------------LFDYAVT-GDVKMLLAVQ--RHLTAVQDE---------
------------------------------NGDSVLHLAIIHLHSQLVRDLLEVTSGLIS
-DDIINMRNDLY-----QTPLHLAVITKQEDVVEDLLRAGA------DLSLL----DRLG
NSVLHLAAK-----EGHD--KVLSI--LLKH--KKAALL-LDHPNGDGLNAIHLAMMSNS
--LPCLLLLVAAGADVNAQEQKSGRTAL--HLAVEHDNISLAGCLLLEGDAHVDSTT---
-----------------Y---------------------DGTTPLHIAAGRGS-------
-----TRLAALLKAA---GADPLVENFEPL----------------Y-----DLDDSWEN
AGE------------------------------------DEGVV----------------
----------------------------PGTTPLDMAASWQVFDILNGKP---Y-EPEFT
SDDLLA-QGDMK------------------------------------------------
-----QLAEDVKLQLYKLLEIPD-P-DKN------WATL--AQKLGLGILNNAF------
-R---------------------LSPAPSKTLMDNYEVS-GGTVR-------E------L
VEALRQM---------GYTEAIEVIQAA-----------SSPVKTTSQAHSLPLSPASTR
QQID--E---LRDSDSVCDS-GVETSFRKLSF-----------------TESLT-SGGSL
LTLNKMPHDYGQEGPLEGKI-------
>gi|114326269|ref|NP_001001840.	Danio rerio
-----------------MAGALRMDDTHY---QIGFVVNEPMTFPSAYD-DLPYMPEA--
----FEVKHEPF----VQETVDGPYIQIIE----EPKQRGFR--FR--------------
-----------------------------YECEGPSHGG---------------------
----LPGAS---SERNRRTYPTVKVL----------------------------------
-NFVGNARVEVQL-----VTHTDP-P-RVHAHSLVGRHCNESGVCSVDVGPSDFTAQFSN
--LGILHVTKRGVVEVLTK-----RLKE--E--------KRKVKGPGY------------
-----KFSDAE----------ENALMQEAKELGKNMDLNIV---------------RLKF
TAYLQDSNGSYTRALK--PVVSNPIYDSKSPNASNLKISRMDKTSGSVL-GGEE---VFL
LCDKVQKD---DID-IRFYEEEDE----WEALGDFSPTDVHKQYAIVFKTPPYRCTNIDR
PVTVFLQLKRKKGGDCSEPKQFTYVPHNQDKEEVQRKRMKALP---DH-YGGWRGGPQGG
AG----------------GF-GGPG--SGTGGGGGM------G--GG-------------
---------------FP------FNPMDN---------SSF-----------------FV
GGC---------------------------------------------------------
------------------------------------------------------------
--------------------------------GGFGGGA---------------------
---------------------------QMSDSPPQTDG------------ANTQSQSNSQ
IRQQLI-----QIALH--------------------------------------------
------------------------------------------------------------
------------------------------------NRANLAAKCNA-------------
------RA--------------LLQYSST-GDARPLLALQ--RHLCGVQDE---------
------------------------------NGDTPLHLAIIHQKTVVAEQLIKALNSSPQ
-QKFFNKLNKLS-----QAPLHLAVITKQPKLVEMLMKSGA------DPSLL----DREG
RTVLHLAAH-----TGDD--VILRL--VLSLLGEHHSHL-INSADFTGQYPVHLAVKKDG
--ERCLRLLVEAGAKINMPEQKSGCTAL--HLAVRDNLLKLACNLITELKADVNACT---
-----------------Y---------------------GGNSPLHLAASQGS-------
-----PHLCSMLIAA---GADKRIENDEPL----------------FLSSSSSDEDEESE
KKL------------------------------------SEDMVQQVHCLSISSERGVFN
PR----------------------KRPAAGHTPFDLAKSQKVRDLLDGRKGPKP-NSLSP
KRTKISTEEVNQ------------------------------------------------
-----DLDNEVLSKLCGILIHDDVP----------WREL--AEKLGMLTLTHLY------
-Q---------------------DSASPCQKLLESYQLS-GGPVD-------G------L
VEALQAL---------GVREGVRLLRDS--------------------------------
QPRE--D---KQSSDSTEDS-GFGSQSIGEEM-----------------AN---------
--------------PAVGNH-------
>gi|62644423|ref|XP_342347.2|	Rattus norvegicus
----------------------MADDDPF------GTGQM-FHLNTALT-HSIFNAEL--
----YSTDI-------PLST-DGPYLQILE----QPKQRGFR--FR--------------
-----------------------------YVCEGPSHGG---------------------
----LPGAS---SEKNKKSYPQVKIC----------------------------------
-NYVGPAKVIVQL-----VTNGKN-I-HLHAHSLVGKHC-EDGICTVTAGPKDMVVGFAN
--LGILHVTKKKVFETLEA-----RMTE--A--------CIRGYNPGLLVHSDLAYLQAE
GGGDRQLTDRE----------KEIIRQAALQQTKEMDLSVV---------------RLMF
TAFLPDSTGSFTRRLE--PVVSDAIYDSKAPNASNLKIVRMDRTAGCVT-GGEE---IYL
LCDKVQKD---DIQ-IRFYEEEENG-GVWEGFGDFSPTDVHRQFAIVFKTPKYKDVNITK
PASVFVQLRRKSDLETSEPKPFLYYPEIKDKEEVQRKRQKLMPNFSDS-FGG-----GSG
AG----------------AG-GGGM--FGSGGGGGGSTGSP-G--PG-------------
---------------YG------FPHYGF---------PAY----GGIA---------FH
PGA---------------------------------------------------------
------------------------------------------------------------
----------------------------TKSNTGITHGT---------------------
---------------------------INTKFKNEPRD------------CAKSDDREIL
NPPEK-------ETQG-----------EGPSLFMASTKTEAIAPASTMEDKEEDVGFQDN
LFL---------------------------------------------------------
------------------------------------EKALQLAKRHA-------------
------NA--------------LFDYAVT-GDVKMLLAVQ--RHLTAVQDE---------
------------------------------NGDSVLHLAIIHLHAQLVRDLLEVTSGSIS
-DDIINMRNDLY-----QTPLHLAVITKQEDVVEDLLRVGA------DLSLL----DRWG
NSVLHLAAK-----EGHD--KILGV--LLKN--SKAALL-INHPNGEGLNAIHIAVMSNS
--LSCLQLLVAAGAEVNAQEQKSGRTAL--HLAVEYDNISLAGCLLLEGDALVDSTT---
-----------------Y---------------------DGTTPLHIAAGRGS-------
-----TRLAALLKAA---GADPLVENFEPL----------------Y-----DLDDSWEK
AGE------------------------------------DEGVV----------------
----------------------------PGTTPLDMAANWQVFDILNGKP---Y-EPVFT
SDDILP-QGDIK------------------------------------------------
-----QLTEDTRLQLCKLLEIPD-P-DKN------WATL--AQKLGLGILNNAF------
-R---------------------LSPAPSKTLMDNYEVS-GGTIK-------E------L
VEALRQM---------GYTEAIEVIQAA---FRTPETTASSPV-TTAQAHLLPLSSSSTR
QHID--E---LRDNDSVCDS-GVETSFRKLSF-----------------SESLT-GDGPL
LSLNKMPHNYGQDGPIEGKI-------
>gi|114595411|ref|XP_001168701.	Pan troglodytes
--------------MKRTTSFRMAEDDPY----LGRPEQM-FHLDPSLT-HTIFNPEV--
----FQPQM-------ALPTADGPYLQILE----QPKQRGFR--FR--------------
-----------------------------YVCEGPSHGG---------------------
----LPGAS---SEKNKKSYPQVKIC----------------------------------
-NYVGPAKVIVQL-----VTNGKN-I-HLHAHSLVGKHC-EDGICTVTAGPKDMVVGFAN
--LGILHVTKKKVFETLEA-----RMTE--A--------CIRGYNPGLLVHPDLAYLQAE
GGGDRQLGDRE----------KELIRQAALQQTKEMDLSVV---------------RLMF
TAFLPDSTGSFTRRLE--PVVSDAIYDSKAPNASNLKIVRMDRTAGCVT-GGEE---IYL
LCDKVQKD---DIQ-IRFYEEEENG-GVWEGFGDFSPTDVHRQFAIVFKTPKYKDINITK
PASVFVQLRRKSDLETSEPKPFLYYPEIKDKEEVQRKRQKLMPNFSDS-FGG-----GSG
AG----------------AG-GGGM--FGSGGGGGG-TGST-G--PG-------------
---------------YS------FPHYGF---------PTY----GGIT---------FH
PGT---------------------------------------------------------
------------------------------------------------------------
----------------------------TKSNAGMKHGT---------------------
---------------------------MDTESKKDPEG------------CDKSDDKNTV
NLFGKV-----IETTE-----------QDQEPSEATVGNGEVTLTYATGTKEESAGVQDN
LFL---------------------------------------------------------
------------------------------------EKAMQLAKRHA-------------
------NA--------------LFDYAVT-GDVKMLLAVQ--RHLTAVQDE---------
------------------------------NGDSVLHLAIIHLHSQLVRDLLEVTSGLIS
-DDIINMRNDLY-----QTPLHLAVITKQEDVVEDLLRAGA------DLSLL----DRLG
NSVLHLAAK-----EGHD--KVLSI--LLKH--KKAALL-LDHPNGDGLNAIHLAMMSNS
--LPCLLLLVAAGADVNAQEQKSGRTAL--HLAVEHDNISLAGCLLLEGDAHVDSTT---
-----------------Y---------------------DGTTPLHIAAGRGS-------
-----TRLAALLKAA---GADPLVENFEPL----------------Y-----DLDDSWEN
AGE------------------------------------DEGVV----------------
----------------------------PGTTPLDMATSWQVFDILNGKP---Y-EPEFT
SDDLLA-QGDMK------------------------------------------------
-----QLAEDVKLQLYKLLEIPD-P-DKN------WATL--AQKLGLGILNNAF------
-R---------------------LSPAPSKTLMDNYEVS-GGTVR-------E------L
VEALRQM---------GYTEAIEVIQAA-----------SSPVKTTSQAHSLPLSPASTR
QQID--E---LRDSDSVCDS-GVETSFRKLSF-----------------TESLT-SGASL
LTLNKMPHDYGQEGPLEGKI-------
>gi|118343894|ref|NP_001071772.	Ciona intestinalis
----------------------------------------------MSD-QSLVLHQS--
----TRENM-------FPEENGEPYLEIIE----NPKSRGFR--FR--------------
-----------------------------YTCEGPSHGG---------------------
----IPGGS---SDKNKKTFPAVKIC----------------------------------
-NYQGYARIVVQL-----VTNEEN-P-RLHPHSLVGKQC-QNGICTVQCGPKDMTATFPN
--LGIQHVTKKNVATILEE-----RYIAAEM--------QLSSINDGF-----------P
QEVQRNIKDED----------RKRIAAKAQSEAKSIDLSVV---------------RLMF
IAYLPDSNGAFTIMLK--PVISDAIFDSKAPNAATLKICRMDCNAGSAS-GGDE---VYL
LCDKVQKD---DIQ-VVFSEEDMQGNNLWEAYGSFSPTDVHRQFAIVFRTPAYKDTEIKM
PVNVQVQLRRKSDNEVSESRPFTYLPNKSDLELIDRKRRKVMPDFLDH-TGN-----GST
GGYSFNPQAAILPSSYNFSGNTGSG--NTAGNGAGKVKEARRP--PQKQQNPQKGPVDPS
VLMMLNRIKTEPKSPSPPTTYSNFPPIAYMSPAKSEPSPPAPMSIGGSPAAQVPQEEEYL
PGTRIPLPKNARPHTGLPQMSFQNPIVLSQQQQMQQQQIQQQQQQHLQQIQQQQAYSNYS
PMYSTTYGLDNTQHMVYSTPSPDYGQQIIQQLSPQEVQEYEETVMNELSTVDAGDLVDIM
NVDLNHNPMPQTTNSNIINQAYDQANILTQTNNTYGGGSGSFRGSVVDPIIPQPLSNAPL
PILSQQFSQQLLELTEYDLADIESDAGAERKPKPGNNNDDEQEEDYASAYCEEQDTTDST
AHEAEPKSFSTVQSDC-----------CNVEADAAMLKMEKLSLAPSMPTKLDSLKPEKK
FDSKQVETKTKGPLKRSVTSTTASVTQALE------------------------------
------------------------------------KYAVKTMNRNS-------------
------SA--------------LHDFSVT-GDIRMLLVLQ--RHLTDVRDC---------
------------------------------NGDSVLHVAVIHDQMQVLSSLLDVIVTLNN
KQNIIDAVNPQK-----QTALQMAVLSDNVDAVIDLLKVGA------DPLVL----DSYG
NHSIHVACR-----HGNA--DILNR--LLNC--KQVYDMEMDTKNFDGLGCFHLAGKASS
GTRQCLGLLREFAFDVNMPDMKSRRTAL--HMAVEADNIVVAGCLISECDADLEAST---
-----------------Y---------------------EGYTPLHVAASLDH-------
-----CEIATLLLAC---GADPEASSAPP-------------------------------
-----------------------------------------GRE----------------
----------------------------DGMTPLDLATSDQMRDLLNGVFMKNI-KEELD
NSNYSD-EEDLA------------------------------------------------
-----TLDPLIRLKLCKLLNLEK-S-GSD------WYAL--ASRLSLDYIVPFI------
-D---------------------TTENPTDLLLDNYMFK-HGTVA-------G------L
RSALMNI---------GRHDAVQLLNRA-----------------------------ATT
TCVDKFD----SNATEQCDS-AFGSLPNQIDV-----------------I----------
---------------------------
