>gi|123368|sp|P07156|HMGB1_CRIG	Cricetulus griseus
------------------------------------------------------------
------------------------------------------------------------
---------------------------------------------------------VNF
SEFSKKCSERWK----------TMSAKEKGKFEDMAKADKARYE--REMKTYIPPKG---
--ETKKK-F-KDPNAPKRPPSAFFLFCSEYRPKIKGEHPGLSIGDVAKKLGEMWNNTAAD
DKQPYEKK-----------AAKLKEKYEKD-------IAAYRAKGK--PDAAKK-GVVKA
EKSKKK--KEEEDDEEDEEDEEEE----------------------EEEEDEDEEEDDDD
E------------------------
>gi|149635755|ref|XP_001508702.	Ornithorhynchus anatinus
------------------------------------------------------------
----------------------------------------------------MGKG----
---------------------DPKKP--RGK---MSSYAFFVQTCREEHKKKHPDAAVNF
SEFSKKCSERWK----------TMSAKEKGKFEDMAKADKVRYE--REMKTYIPPKG---
--ETKKK-F-KDPNAPKRPPSAFFLFCSEYRPKIKGEHPGLSIGDVAKKLGEMWNNTAAD
DKQPYEKK-----------AAKLKEKYEKD-------IAAYRAKGK--PDVGKK-GVAKA
EKSKKK--KEEEEDEDDDEDDEED----------------------EEDEDEDDEDDDDD
E------------------------
>gi|97976795|tpe|CAJ29302.1|	Schistosoma mansoni
------------------------------------------------------------
---------------------------------------------------MMVK-----
---------------------DKNRP--KPP---MTPYACFVQVIREEHRKKHPTENVIF
SEFSKKCAEKWK----------LMNMEQRKCFEEMAKLDTERFN--REMAHYIPPVG--M
KRGRRRRRI-KDPSMPKRSWSAFFFFCDAFRSKIRSEHPDWKVSDIAKELGRRWEECS--
DKEKYERR-----------AQNDKLRYEQD-------MEKYKA-GL--YVATKRARVGDQ
TKSNEILSCLHDQSHHKELGEASQ-------------------ISSDEVGRGRRTANVSK
EPSMPKTFNGLHFSSFANAFRIKNS
>gi|27881711|gb|AAH44715.1|	Xenopus laevis
------------------------------------------------------------
----------------------------------------------------MGKG----
---------------------DPNKP--RGK---MSSYAYFVQTCREEHKKKHPDTSVNF
SEFSKKCSERWK----------SMSAKEKGKFEDLAKGDKARYE--REMKTYIPPKG---
--ETKGKRK-KDPNAPKRPPSAFFIFCSEHRPQIKSETPGLSIGDTAKKLGELWAEQTPK
DKLPHEQK-----------AAKLKEKYEKD-------VAAYRAKGK--SDVGKK-VPGRA
TGSKKK------VEPEEDDDEEDE----------------------DEEDEEDEDDDDDD
E------------------------
>gi|90103305|gb|ABD85497.1|	Ictalurus punctatus
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------QTCREEHKKKHPDTSVNF
SEFSKKCSERWK----------TMSAKEKGKFEDMARLDKARYE--REMKNYVPPRG---
--EKKKR-F-KDPNAPKRPPSAFFIFCAEYRPKVKEETPGLSIGDVAKKLGEMWNKTSAE
EKQPYEKK-----------AAKLKEKYEKD-------IAAYR-KGK--VVGGAAKAPTKP
DKAD------------DDEDDDDD-------------------------EDDDDDDDEDD
E------------------------
>gi|37779034|gb|AAP20177.1|	Pagrus major
------------------------------------------------------------
----------------------------------------------------MGK-----
---------------------DPKKP--RGK---MSSYAYFVQTCREEHKKKHPEASVNF
AEFSKRCSERWK----------TMSPKEKGKFEDMAKLDKVRYE--REMKNYIPPKG---
--HKKKR-F-KDPNAPKRPPSAFFLFCADFRPKVKGDYPGLSIGDTAKKLGEMWNSSSAE
EKQPYEKK-----------AAKLKEKYDKD-------IVAYRTKGK---------VDSES
AATADD----------DDEEEEDE----------------------EEGEDEEEDDDDDD
E------------------------
>gi|119619804|gb|EAW99398.1|	Homo sapiens
------------------------------------------------------------
--------------------------------MQRMEILPARKRNPFIIRIRMAKG----
---------------------DPKKP--KGK---MSAYAFFVQTCREEHKKKNPEVPVNF
AEFSKKCSERWK----------TMSGKEKSKFDEMAKADKVRYD--REMKDYGPAKG---
--GKKK----KDPNAPKRPPSGFFLFCSEFRPKIKSTNPGISIGDVAKKLGEMWNNLNDS
EKQPYITK-----------AAKLKEKYEKD-------VADYKSKGK--FDGAK--GPAKV
ARKKV-----------EEEDEEEE-------------------------EEEEEEEEEED
E------------------------
>gi|114689875|ref|XP_529110.2|	Pan troglodytes
------------------------------------------------------------
--------------------------------MADTCCAWQRAINSGNNTVRMAEG----
---------------------DHKKP--KGK---MSAYAFFAQTCREEHKKKNPEVPVNF
VEFSKKCSEKRK----------TMSGKEKTKFDEMAKVDKVHYD--QEMKDNGPVEG---
--GKK-----KDPNALKRPLSGFFLFCSEFHPKIKSTNPGISIGDMAKKLGEMWINYSDR
EKQPYITK-----------AADLKEKYEKD-------VADYKSKGK--FDSAK--GPTKI
AWKKVK--------EKDKEDEEEE--------------------------EEEEEKKEEG
E------------------------
>gi|23396867|sp|Q9N1Q5|SP100_HY	Hylobates lar
------------------------------------------------------------
---------------------------------KKCIQSEDKKWFTPREFEIEGDRRASK
NWKLSIRCGGYTLKFLMENKLLPEPPSTRKKRILKSHNNTLVDPC-AVHKKKNPDASVNL
SEFLKKCSEMWK----------TIFAKEKGKFEDMAKADKAHYE--REMKTYIPSKG---
--EKKKK-F-KDPNAPKRPPLAFFLFCSEYRPKIKGEHPGLSIDDVVKKLAEMWNNTAAA
DKQFYEKK-----------AAKLKEKYKKD-------IAADRAKGK--PNSAKK-RVVKA
EKSKKK---------------------------------------------KEEEEDEVD
E------------------------
>gi|52219178|ref|NP_001004674.1	Danio rerio
------------------------------------------------------------
----------------------------------------------------MVKG----
---------------------DVNKP--KGK---TSAYAFFVQTCRDEHKRKSPDVPVNF
SEFSKKCSERWK----------SLNASDKVKFEDMAKADKVRYD--REMKTYVPPKG---
-VGKTGRKK-KDPNAPKRPPSAFFVFCSEYRPTVKSEHPNLTIGEIAKKLGELWSKQSSK
DRAPFEQK-----------AGKLREKYEKE-------VAAYRAGGG--ASKR---GPGRP
TGSVKK--SQAEADDDDDEDEDEE-----------------------DEEDDEEEEDEDD
E------------------------
>gi|118343822|ref|NP_001071733.	Ciona intestinalis
------------------------------------------------------------
---------------------------------------------------MPTKK----
---------------------DPNKP--RGR---MTGYAYFVQTCREEHKRKHPNEQVVF
AEFSRKCAKRWK----------PMTDKEKKTFTDMAEKDRQRYE--REMKDYVPAAG---
--EAKKKKKKKDPNAPKRPQSAFFLFCADRRAPLKAENPGWTVGEIAKALGKKWAAASPD
TKKKYAEQ-----------GEVEKSKYNKE-------MEKYRSQQE---------ASNHG
DAKRQK----------MSEKATAS----------------------SSASSSESESDIES
D------------------------
>gi|123382|sp|P07746|HMGT_ONCMY	Oncorhynchus mykiss
------------------------------------------------------------
----------------------------------------------------MGK-----
---------------------DPRKP--RGK---MSSYAYFVQTRREEHKKKHPEASVNF
SEFSKKCSERWK----------TMSAKEKGKFEDLAKLDKVRYE--REMRSYIPPKG---
--EKKKR-F-KDPNAPKRPSSAFFIFCADFRPQVKGETPGLSIGDVAKKLGEKWNNLTAE
DKVPYEKK-----------ASRLKEKYEKD-------ITAYRNKGK--VPVS---MPAKA
AAPAKD----------DDDDDDDD----------------------DDDEDDDDDDDEDD
E------------------------
>gi|38018014|gb|AAR08136.1|	Suberites domuncula
------------------------------------------------------------
---------------------------------------------------MPPKK----
---------------------DPNKP--KGR---TSAYAFYVQERRDIYRKN--GDTVVF
APFSQECAELWK----------NV--KDKKAYQDMAAVDKERYD--REMAEYVPPDDG--
--EKSKKKKQKDKTKPKRSLTAFLFFCSEERPKMKEKNPGSSVGDLAKLLGAKWKGMSED
DKQPFSDM-----------AQDDKDRYNDE-------MALWK-KGQ--FN----------
----------------------------------------------RQEEEEGADYSEEE
D------------------------
>gi|29825377|gb|AAO92280.1|	Dermacentor variabilis
------------------------------------------------------------
----------------------------------------------------MGKG----
---------------------D--KP--RGR---MSAYAFFVQTCREEHKKKHPNENVVF
AEFSKKCAERWK----------TMSESEKKRFHQMADKDKKRFD--TEMADYKPPKG---
-DKSKKRKRAKDPNAPKRPLSAFFWFCNDERPNVRQESPDASVGEVAKELGRRWNEVGDD
VKSKYEGL-----------AAKDKARYEKE-------LKAYKGKKP------KAASPPKE
KAKKKE-------EDDDEDDDDEE----------------------DEVEDAEDDDDDDE
D------------------------
>gi|125982273|ref|XP_001355062.	Drosophila pseudoobscura
--------------------------------MASSFPNPATTMAQVVATSNAAGTTGYD
YRLNMAQAAAAAAVPGSQWWYSAANQGQVDANTAAQLLFVLAKKQNRMEPQHKNQPIYRL
SLILDHYCFCFQQSPMVRGGKADAKP--RGR---MTAYAYFVQTCREEHKKKHPDETVIF
AEFSRKCAERWK----------TMVDKEKKRFHEMAEKDKQRYE--AEMQNYVPPKGTVV
GRGKKRKQI-KDPNAPKRSLSAFFWFCNDERNKVKALNPEYGVGDIAKELGRKWSDVDPE
VKQKYESM-----------AERDKARYERE-------MTEYKTSGK--IAMSAPSMQASM
QAQAQK------------------------------------AALLAAAVQQQQQHQLDE
Q------------------------
>gi|115495357|ref|NP_001069753.	Bos taurus
------------------------------------------------------------
----------------MESLPSMSKKTTCSTGADMESLPSTSKKTKFVLRVKMAKG----
---------------------DPKKP--KGK---MSAYAFFVQTCREEHKKKNPEVPVNF
AEFSKKCSERWK----------TMSGKEKSKFDEMAKADKVRYD--REMKDYGPAKG---
--GKKK----KDPNAPKRPPSGFFLFCSEFRPKIKSANPGISIGDVAKKLGEMWNNLSDS
EKQPYINK-----------AAKLKEKYEKD-------VADYKSKGK--FDGAK--GAAKV
ARKKV-----------EEEDEEDE-------------------------EEEEEEEEEED
E------------------------
>gi|46394418|gb|AAS91553.1|	Branchiostoma belcheri
------------------------------------------------------------
----------------------------------------------------MPK-----
---------------------DKNKP--KGK---MSAYACFVQECRREHEKKYPNKQVVF
TEFSQKCASRWK----------TMNDDEKKRFQALAEADKRRYE--QDMAKYVPPKG--A
EGGRRKRKK-KDPNAPKRAMSAFFMYCADARPKVRAAHPDFQVGDIAKILGKQWKEISDS
DKAKYEKK-----------AQTEKARYQKE-------LAEYKRSGGG-ASPAKKGRPAKK
APPPKRVEEEDDDDEDEDEEEEEE----------------------EEDEDEDDEEDEED
E------------------------
>gi|90086209|dbj|BAE91657.1|	Macaca fascicularis
------------------------------------------------------------
----------------------------------------------------MGKG----
---------------------DPNKP--RGK---MSSYAFFVQTCREEHKKKHPDSSVNF
AEFSKKCSERWK----------TMSAKEKSKFEDMAKSDKARYD--REMKNYVPPKG---
--DKKGK-K-KDPNAPKRPPSAFFLFCSEHRPKIKSEHPGLSIGDTAKKLGEMWSEQSAK
DKQPYEQK-----------AAKLKEKYEKD-------IAAYRAKGK--SEAGKK-GPGRP
TGSKKK-------NEPEDEEEEEE----------------------EEEDEDEEEEDEDE
E------------------------
>gi|109504104|ref|XP_001054623.	Rattus norvegicus
--------------------------------MPSRGRGRVCGDESRLQPEDRRRCGLRL
VSSSCRGAENSAKQEAGDCVSDKPVLAGAWGRKSLCGGLREELAPGRRCAVIMGKG----
---------------------DPNKP--RGK---MSSYAFFVQTCREEHKKKHPDSSVNF
AEFSKKCSERWK----------TMSAKEKSKFEDLAKSDKARYD--REMKNYVPPKG---
--DKKGK-K-KDPNAPKRPPSAFFLFCSEHRPKIKSEHPGLSIGDTAKKLGEMWSEQSAK
DKQPYEQK-----------AAKLKEKYEKD-------IAAYRAKGK--SEVGKK-GPGRP
TGSKKK-------NEPEDEEEEEE----------------------EEDDEDEEEEDEDE
E------------------------
>gi|149726074|ref|XP_001503141.	Equus caballus
------------------------------------------------------------
----------------------------------------------------MGKG----
---------------------DPKKP--RGK---MSSYAFFVQTCREEHKKKHPDASVNF
SEFSKKCSERWK----------TMSAKEEGKFEDMAKADKARYE--REMKTYIPPKG---
--ETKKK-F-KDPNAPKRPPSAFFLFCSEYHPKIKGEHPGLSIGDVAKKLGEMWNNTAAD
DKQPYEKK-----------AAKLKEKYEKD-------IAAYRAKGK--PAAAKK-GVVKA
EKSKKK--KEEEEDEEDEEDEEEE----------------------EDEEDEDEEEDDDD
E------------------------
>gi|51592117|ref|NP_001004034.1	Sus scrofa
------------------------------------------------------------
----------------------------------------------------MGKG----
---------------------DPKKP--RGK---MSSYAFFVQTCREEHKKKHPDASVNF
SEFSKKCSERWK----------TMSAKEKGKFEDMAKADKARYE--REMKTYIPPKG---
--ETKKK-F-KDPNAPKRPPSAFFLFCSEYRPKIKGEHPGLSIGDVAKKLGEMWNNTAAD
DKHPYEKK-----------AAKLKEKYEKD-------IAAYRAKGK--PDAAKK-GVVKA
EKSKKK--KEEEEDEEDEEDEEEE----------------------EDEEDEEEEEDDDD
E------------------------
>gi|108872320|gb|EAT36545.1|	Aedes aegypti
------------------------------------------------------------
----------------------MGGTKEGDRDRVTNQTHVQVQNNAVQSKITNSRPV---
---------------------KDNKP--RGR---MTAYAFFVQTCREEHKKKHPEEQVIF
AEFSRKCAERWK----------TMLDKEKQRFHEMAEKDKQRYE--LEMQNYVPPKGTVV
GRGKKRKAF-KDPNAPKRSLSAFFWFCHDERNKVKALNPEYGVGDIAKELGRKWSDMDAE
VKSKYEQM-----------AEKDKARYEQE-------MTEYKLKCKN-EQGGGGGTPLNL
GGLQQTGLQNLPQHVQQAAAAQLQAQVQQQLAAQAAVAAAAQAAAHHADDDDDDVDEDDN
E------------------------
>gi|72051831|ref|XP_792040.1|	Strongylocentrotus purpuratus
------------------------------------------------------------
--------------------------------------------------MVKQKK----
---------------------DPNKP--RGR---MSAYAYFVQ-----DRRSKAEGQVNF
TAFSKECADRWK----------HMDDGDKRPFNDKSASDKIRYD--REMSGYVPPMKEKN
AKGGRRRAK-KDPDAPKRNLSAFFLFSRDERGAIKQEHKDWSVGKIAQALAAIWKTITPA
DKAKYDAE-----------AALEKQRYMRE-------MAAFKESKP---------KQVKK
QQRKES----------SSSSSSDD----------------------STSDDSSSDSDSDE
E------------------------
>gi|109083171|ref|XP_001106417.	Macaca mulatta
------------------------------------------------------------
---------------MQAEPRQRPPWQLRAPHRPAGFPSPFSAPSGGRRSVTMGKG----
---------------------DPNKP--RGK---MSSYAFFVQTCREEHKKKHPESSVNF
AEFSKKCSERWK----------TMSAKEKSKFEGMAKSDKVCYD--REMKNYVPPKG---
--DKKGK-K-KDPNAPKRPPSAFFLFCSEHRPKIKSEHPGLSTGDTAKKLGEMWSEQSAK
DKQPYEQK-----------AAKLKEKYQKD-------IAAYRAKGK--SEAGKK-GPGRP
TGSKKK-------NEPEDEEEEEE----------------------EEEDEDEEEEEEDE
E------------------------
>gi|1419611|emb|CAA67363.1|	Lampetra fluviatilis
------------------------------------------------------------
----------------------------------------------------MGKG----
---------------------DPKKP--KGK---MSSYAYFVQTCREEHKKKNPEASVNF
AEFSKKCSERWK----------TMSEKEKTRFEDMAKVDKVRYD--REMKTYVPPKG---
--ERGSRKK-KDPNAPKRPPSAFFIYCAEYRSKVRAENPGLTIGSIAKKLGEMWNNAPAD
EKSIYERK-----------TAKLKEKYDKD-------MASYRSKGK--VETSK--VASKP
ASKQRD--------DDDDEDDDEE-----------------------DDEDEDEDDDDDD
E------------------------
>gi|148668459|gb|EDL00778.1|	Mus musculus
------------------------------------------------------------
----------------------------------------------------MGKG----
---------------------DPKKL--RGK---MSSYAFFVQTCREEHKKKHPDASVNF
SEFSKKCSERWK----------TMSAKEKGKFEDMAIADKARYE--REMKTYIPPKR---
--ETKKK-F-KDPNAPKRPPSAFFLFCSGYRPKIKGEHPGLSIGDVAKKRGEMWNNTAAD
DKQPMRRRLLRRSMRRILLPTELKENLMQR-------KRGWSRLKRA-RKRRKRKMMRRM
KRMRKRRKKRKMKMKKKMMMMNKL---------VLELFFFLIYKAFNPPVHNSLLLKKKI
EM-----------------------
>gi|126327419|ref|XP_001367246.	Monodelphis domestica
------------------------------------------------------------
----------------------------------------------------MGKG----
---------------------DPKKP--RGK---MSSYAFFVQTCREEHKKKHPDASVNF
SEFSKKCSERWK----------TMSAKEKGKFEDMAKADKVRYE--REMKTYIPPKG---
--ETKKK-F-KDPNAPKRPPSAFFLFCSEYRPKIKGEHPGLSIGDVAKKLGEMWNNTAAD
DKQPYEKK-----------AAKLKEKYEKD-------IAAYRAKGK--PDVGKKGGVVKA
EKSKKK--KEEEEDEEDEEDEDDD----------------------EEDEEEEEEDDDDD
E------------------------
>gi|52345682|ref|NP_001004888.1	Xenopus tropicalis
------------------------------------------------------------
----------------------------------------------------MAKG----
---------------------DPKKP--KGK---MSAYAYFVQTCREEHKKKNPEIPVNF
AEFSKKCSERWK----------TMSAKEKSKFDDLAKADKVRYD--REMKDFGPVKK---
--GKKK----KDPNAPKRPPSGFFLFCSEFRPKIKSTNPGISIGDVAKKLGEMWNNLNDG
EKQPYNNK-----------AAKLKEKYEKD-------VADYKSKGK--FDCAK--GAPKL
ARKKEE----------DEDDDDED------------------------EEEDEEDEEDDD
D------------------------
>gi|47190944|emb|CAF93003.1|	Tetraodon nigroviridis
------------------------------------------------------------
-------------------------------------------------AATMMRK----
---------------------DVNKP--KGK---TSAYAFFVQTCREEHRKKNPEQSVNF
AEFSKKCSERWK----------ALSAGDKKCFEDMAKADKVRYN--REMRDYVPPKG---
-FGKRGRKR-KDPNAPKRPPSAFFVFCSEYRPSVKQQFPGLSIGDCAKKLGEMWSKLSQS
EKQPYEEK-----------AQKLREKYDRD-------MVAYR--------GGVSYAARNP
DSSAQG----------GEEEEEDE-------------------------GEEEEEEEEDD
E------------------------
>gi|56757397|gb|AAW26868.1|	Schistosoma japonicum
------------------------------------------------------------
----------------------------------------------------MAE-----
---------------------EKGKP--KGR---MNAYALFLQSMRADHKKKHPNATLDF
KSFSKECSEQWKVSYVLVYYFSNLSAKEKKKFKDLAEKDKERYR--CEMEHYEPPAD---
--EGRSKKRKRDPDAPKKGLSAFFLFCNDERPKVKSENPDWKVSEVAKELGRRWEHC--K
NKAKYESL-----------AQVEKERYEKVSSILLPLLFACLGDGK--IQSRQKAQDRRL
RIRRLV--PNGLKINVLELLYTDG------------VILYCLQMFLFKPNGPSCICKMMA
TVTFFYQIYCL--------------
>gi|73993609|ref|XP_543194.2|	Canis familiaris
------------------------------------------------------------
----------------------------------------------------MGKG----
---------------------DPNKP--RGK---MSSYAFFVQTCREEHKKKHPDSSVNF
AEFSKKCSERWK----------TMSAKEKSKFEDMAKSDKARYD--REMKNYVPPKG---
--DKKGK-K-KDPNAPKRPPSAFFLFCSEHRPKIKSEHPGLSIGDTAKKLGEMWSEQSAK
DKQPYEQK-----------AAKLKEKYEKD-------IAAYRAKGK--SEAGKK-GPGRP
TGSKKK-------NEPEDEEEEEE----------------------EEEDEDDEEEEEDE
E------------------------
>gi|5815432|gb|AAD52670.1|AF178	Gallus gallus
------------------------------------------------------------
----------------------------------------------------MGKG----
---------------------DPKKP--RGK---MSSYAFFVQTCREEHKKKHPDASVNF
SEFSKKCSERWK----------TMSSKEKGKFEDMAKADKLRYE--KEMKNYVPPKG---
--ETKKK-F-KDPNAPKRPPSAFFLFCSEFRPKIKGEHPGLSIGDVAKKLGEMWNNTAAD
DKQPYEKK-----------AAKLKEKYEKD-------IAAYRAKGK--VDAGKK-VVAKA
EKSKKK---KEEEEDEDEDEEDEE----------------------DEEEEEEEEEDDDD
E------------------------
>gi|126309086|ref|XP_001363686.	Monodelphis domestica
------------------------------------------------------------
----------------------------------------------------MGKG----
---------------------DPKKP--RGK---MSSYAFFVQTCREEHKKKHPDASVNF
SEFSKKCSERWK----------TMSAKEKGKFQDMAKADKVHYE--REMKTYIPPKG---
--ETKKK-F-KDPNAPKRPPSAFFLFCSEYRPKIKGEHPGLSIGDVAKKLGEMWNNTAAD
DKQPYEKK-----------AAILKEKYEKD-------IAAYRTKGK--PDVGKKGGIVKA
EKSKKK--KEEEEDEEDEEDEDDD----------------------EEDEEEEEEDDDDN
E------------------------
