>gi|113931336|ref|NP_001039116.	Xenopus tropicalis
MPVR----KQDTQRALTLLEEYRCKLHQTEDKQLRKSIERVIGIFQSNLFQALIDIQEFY
EVTLL----------------------------------------------DNPKSSDNA
KPTEPVQTINTWEYSS------------------LPNSTA--TCETLPSSLILNVEKYRY
PDDDITSQEPSSPHMLNDGRNVELVQISEKNISQKENIQGLVSHSLIS----PLKTPEAD
TPCPPIVPVIPVIPVPAESNVIPSSTPQANPPPVIVNTD-LETPAYVN---GTDAEYEYE
EITLERGTS-GLGFSIAGGTDNPHIGD-DISIFITKIISGGAAAQDGRLRVNDCILRVNE
VDVHDVTHSKAVEALKEAGSIVRLYVRRRKPVTEKIMDI-KLVKGPKGLGFSI-------
------------------------------------------------------------
------------------------------------------------------------
-----AGGVGNQHIPG--------------------------------------------
--------------------------------------DNSIYVTKI---IEGGAAHKDG
RLQIGDKLLAVNTV-CLEEVSHEDAVTALKNTSDFVNLKVAKP-TTMYM-----------
------NDNYAPPDITNSYSQ----------------QVDNHISPSGFIGHP--------
-------LPPSPGRYSPAPKGMLEDDD---------------------------------
-----------------------LTRE-----------------------------PRKV
VLQRGTTG---------LGFNIVGGEDGEGIFISFILAGGPADLSGELQKGDRIMS----
---VNGVDLKSATHEQAAAALKN--AGQTVTIVAQYRPE--------------EYSRFEA
KIHDLREQMMNSSISSGSGSLRTSQKRSLYVRALFDYDKTKDSGLPSQGLNFKFGDILHV
VNASDDE------------WWQARQVTA---DGESEEIGVIPSKRRVEKKERARLKTVKF
N--SKARGDKGQSFNDKRKKNLFSRKFPFYKNKDQSEMETSDVDQHVTSNASDSESSYRG
QEEYVLSYEPVNQQEVNYSRPVIILGPTKDRVNDDLISEFPEKFGSCVP--------HTT
RPKRDYEIDGRDYHFVTSREQMEKDIQDHRFIEAGQYNSHLYGTSVQSVKEVAERGKHCI
LDVSGNAIKRLQIAQLYPIAIFIKPKSVENIIEMSKRV---TEEQGRKTYERAMKLEQEF
TEHFTAIVQGDTLEE-IYNQIKQIIEEQSSTFIWVP--------AKEKL-----------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
----------------------
>gi|59933258|ref|NP_001012378.1	Danio rerio
-------------------------------------------------MKAVVRVLKLE
ERAV------------------------------HRQQNRPPAVQGSQHQSHSPACM---
--NPALMS-SPWVRQKH-------------GGRAIPNRLCLSTTDSP--------HSYRY
QDDDSPPPEHSFPRLTNEVRAPELVHVSEKNLSEIENVHGYVSHSHIS----PLK-----
----------------------------ASPAPIIVNTDTLESVPYVN---GTEIEYEFE
EITLERGNS-GLGFSIAGGTDNPHIGD-DPGIFITKIIPGGAAAEDGRLRVNDCILRVNE
SDVSEVSHSKAVEALKAAGSIVRLYVRRRRPMLETVTEI-KLIKGPKGLGFSI-------
------------------------------------------------------------
------------------------------------------------------------
-----AGGVGNQHIPG--------------------------------------------
--------------------------------------DNSIYVTKI---IDGGAAQKDG
RLQVGDRLLMVNNY-TLEEVTHEEAVAILKNTSDVVYLKVGKP-TSVYL-----------
------SDPYGPPDITHSFSP----------------AMENHISSPGNNGTL--------
-EYKSSLPPISPGRYSPLPKHLLGEEDINRNPSLDEMEGHRFDSQ---------------
---------------------HFQLRE-----------------------------PRKI
VLHKGSTG---------LGFNIVGGEDGEGIFVSFILAGGPADLSGELRRGDQILS----
---VNGIDLRGATHEQAAAALKG--AGQTVTIIAQYRPE--------------EYGRFEA
KIHDLREQMMNHSMSSGSGSLRTNQKRSLYVRALFDYERAKDSGLPSQGLSFRYGDILHV
INASDDE------------WWQARRVTP---EGDSEEMGVIPSKRRVERKERARLKTVKF
NAKPGSLDSKGSFSEKRRKNFIFSRKFPFYKNKDADE-----QDGSDSERSQEELIL---
------SYEPVIRQEINYARPVIILGPMKDRINDDLISEFPDKFGSCVPPANSSDQEDTT
RPKRDYEVDGRDYHFMASREQMEKDIQEHKFIEAGQYNDNLYGTSVQSVKYVAERGKHCI
LDVSGNAIKRLQVAQLYPIAIFIKPRSIESLMEMNKRL---TEEQAKKTYDRAMKLEQEF
GEYFTALVQGDTLED-IYNQCKMVIEEQSGPYIWIP--------SKEKL-----------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
----------------------
>gi|126334826|ref|XP_001373810.	Monodelphis domestica
------------------------------------------------------------
------------------------------------------------------------
-------------------------------------------------------MPVKG
DRLFPYRRELSAWVPAPGM-----------------------------------------
----------------------------------------------------EELIWEQY
TVTLQKDSKRGFGIAVSGGRDNPHFENGETSIVISDVLSGGPA--DGLLQENDRVIMVNG
TPMEDVPHSFAVQQLRKSGKIAAIVVKRPRKVQLAPLRGDSSSMDPDERVFHV-MDDREE
FDGRSARSGYSERSWHSGNGGRSRS-WENS------PERRLPHDQPRGRER--SYSRERS
RGRSLERGLDQ--DYRR--DRSQGRSIDR------------------------------D
DGY--DRGHRRDYSPSVEYSQRHSANARYEMK-RSQSRDQLHSRSPTPEMRRRSE---Q-
-------------RD-IERPIDVLLTKSKSNEEYGLRLGSQIFIKEM---TRTGLATKDG
NLHEGDIILKINGT-VTENMSLADARKLIEKSRGKLQLVVLRD-SKQTLINIPSLHDSDS
E-----IEDISEIESNRSFSP--------DERR---TDFDYHSSNEKLKERT------NS
REETSNRLSKMGA--TPTPFKSTGDIVTAVFQ--ENNKEPKYQEDPPV---SQPKA----
---APRTFLRPSPEDE-----AIYGPN-----------------------------TKMV
KFKKGDS----------VGLRLAGGND-VGIFVAGIQEGTSAEQEG-LQEGDQILK----
---VNTQDFRGLVREDAVLYLLEIPKGEMVTILAQSRAD--------------VYRDI--
-------------LACGRGD-------SFFIRSHFECEKE-----SPQSLAFTRGEIFRV
VDTLYDG---------KLGNWLAVRIG------NELEKGLIPNKSRAEQ-----MASVQN
A-------QRDNSGD--RAD--------FWRMRGQRS----GVKKN-LRKSREDLTAIVS
VSTKFPAYERVLLREAGFKRPVVLFGPIADIAMEKLANELPDLFQTAK-----------T
EPK-----------------------------DAGS-EKSSGVVRLNTVRQIIEQNKHAL
LDVTPKAVDLLNYTQWFPVVIFFNPDSRQGVKTMRQRLNPTSNKSSRKLFDQANKLKKTC
AHLFTGTINLNSTNDSWFGSLKDLIHQQQGEAVWVSEGKLEG--MDDDM-----DDRMSY
LTAMGADY--LSCDSRLISDFEDTDGEGGAYTDNELDEPAE---------E----PQ-VS
SITRSSEPVLHEESIRKP------------SPEPRGQMRRAGSRD---------------
----------------------QL-RDTSPPP----------------------------
----------------------------------------------AFKPEPPKAKLQNK
DE----------------------------------------------------------
---------------------------PYDITKSYEYRPNNSVTASNEIPGA--------
----ATKPYV------PPVP---------------------------LKPAFGRSILKP-
-----STPTFPSQENEEHR---GNGEE-----ANNA---PKSVLGKVKIFEK--MDHKAR
IQRMQELQEA--QNARLEIA-QKHPDIYAVPIKAPKPDLNSTQVT--------SFRPPEP
QKPPSRLYQD-SKGSYGSDIEEEE-YRQQLSEHSKRGYYGQPARY---------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
--------------------------------------------------RDTEL-----
------------------------------------------------------------
----------------------
>gi|110767198|ref|XP_001120987.	Apis mellifera
------------------------------------------------------------
------------------------------------------------------------
-----------------------------------------------------MNVGNSG
NSPNSPSTTHNILHNTSSGTDAQN------------------------------------
----------------------------------------------------GDRGWEIH
HVTVTRVPGYGFGIAVSGGRDNPHFTNGDPAIAISDVLKAGPA--EGKLQVNDRIISANG
ISLEGADYGAAIRVLRDSGSTVLLVVKRRASSNS--------------------------
------------------------------------------------------------
------------------------------------------------------------
-----SGNIGNFTLQS--------------------------------------------
--------------------HRLTLTRNNKKDDFGIVLGCRLYVKEV---TRENIA----
-VKPGDVLTRIGSV-ATDNMSLKEAKKLMDQCKDKLSIVITRD-NSCCHIQ---------
------QQTKNETGEYLSGTT-------------SYSSQNLYVPPPTRQPIE--------
--DKSNLVPRGRARGPLMD-VSLSQLDLPATP---------TVDPPRP---PPPRP----
---EDYYSTRRQLYDEDLTRNKLPMPD-----------------------------PRFI
TFQKEGS----------VGVRLSGGNE-TGVFVTAVQTGSPASLQG-LQPGDKILK----
---INDMDMKGVTREEAVLFLLSLQ--EQIDLIVQHRRQ--------------EYDQV--
-------------IASGKGD-------SFHIKTHFHYEQP-----QKGEMSFRSGDVFHI
IDTLHNG---------VVGSWQVFRIGR---NNQEVQKGIIPNKARAEE-----LATAQF
N-----ATKKEMSASENRGS--------FFRRRKSSH----RRSKSLGRDHWDDVVFSDS
V-SKFPAYERVILRHPGFVRPVVLFGPVADLAREKLLKDFPDKF---------------T
SPQMENQLDD----------------------NVGKNMKSSGIIRLSAIREVMDRGKHAL
LDITPNAVDRLNYAQFYPIVIFLKAETKQIIKEMRAGVPKSAHKSSKKLLEQCQKLDKIW
SHIFSAMITLTTPEA-WYRKLRELIDRQQQGLLWMSQTKPEEA-LSDDFLFPM-TSRLSY
ASSPESDLE-LSPAPALPGALG-APSRLKSNSDPSIATQDD---------IAAPPPPYST
TYQQSFEQPKRRSQGGIGEGKYGFSLSGQVSNQSGSPEYLAGSFEPRSSHHSPPDLPP--
----------------------RVDRNAKPNN----------------------------
-------------------QQQRNTIGRTAQERLLNKADSILDVANYINATPLKANATSS
LE----------------------------------------------------------
--------------------RTQPKAGSYDSMSSYDSYNNTNGNNSYGTPGL--------
-----NTSTGRLGPNVPDDL----------------------------------------
-------------------------KSSAPTRPHDPYRFTRSTAQPIPNHDSQPRTDYAK
YSRTTDYKSITLPQNNKSGG-SYKPIPPPKPKNYRPPQTNLTQPENNGNEGNNTHQHSKS
YSIATSHNHNLSHTHAHCTPPMSTHNHSNSTSQLNLGLSHNRNNINHNG-----------
------------------------------------------------------------
----------------------------YVVNNSHNASGQNFPTSPGHNREPSGLDLAGS
REQRGSAFELYRKPVHHYNAR---------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
----------------------
>gi|156537444|ref|XP_001607015.	Nasonia vitripennis
------------------------------------------------------------
------------------------------------------MTHSSENGEQQESPLSAS
PPPPPPQP--------------------------PPESPVPTKEAFFQQNEISAEPPILE
VLDEPVDEAKGLLLFGIGIRVRSSGLACLVDSSEARLCRAARKVRLLAAGLAAAAHPDNM
EQQSQQQQQQQQQQQRNSSNEAAAGIVVAVASPTTQSPQPEQVGGGCGSGSVTDRGWEVH
QVTVTRVPGYGFGIAVSGGRDNPHFTNGDPAIAISDVLKAGPA--EGKLQVNDRIISANG
VSLEGADYGAAVRVLRDSGSTVLLVVKRRAGPMSAN----CTINGQTGLNQSS-------
------------------------------------------------------------
------------------------------------------------------------
----RSPVTLQPPTPS--------------------------------------------
-----------------TQSIRLSLSRPSKKEDFGIVLGCKLYVREV---TREGTGAR--
---AGDLVTRIAGV-QAENMSLKEARKLMDSSKERLSLVVSRETTTDPNQPAGSFQQQQQ
QQQ---QQQVDGTKGQQQLAG------GADYSGQGYSSQNLYVPPPTRLPSS-------S
SEDKSNLAPRGRSRGPLMD-VSLSQLDLPATP------TQAHKEPPRP---PPPRP----
---EDYYSSRRQMYED-DPLIQRTKPD-----------------------------PRFI
TFQKEGS----------VGVRLTGGNE-TGVFVTAVQPGSPASLQG-LQPGDKILK----
---VNDMDMKGVTREEAVLFLLSLQ--EQIDLIVQHRRQ--------------EYEQI--
-------------VASGKGD-------SFHIKTHFHYEQP-----DKGEMSFRSGDVFHV
VDTLHNG---------VVGAWQVYRIGR---NNQEVQKGIIPNKARAEE-----LATAQF
N-----ATKKEMSASESRGS--------FFRRRRGSH----RRSKSLGRDHWDDVVFSDS
V-SKFPAYERVVLRHPGFIRPVVLFGPVADLAREKLLKDFPDKF---------------T
SPQ-----------------------------EGGKSTKSSGIIRLSAIREVMDRGKHAL
LDITPNAVDRLNYAQFYPIVIFLKAETKQMIKEMRVGVPKSAHKSSKKLLEQCQKLDKIW
GHVFSAVITLNSPES-WYRKLRELIDWQQQGPLWMSQTKPEEA-LSDDFLFPM-TSRLSY
ASSPESDLE-LSPAPPLPGALG-VPSRLKSSSDPSIATQDD----------AVAPPPYTT
SYQLSQLQQAAFESQQQQ------------------QMQSPPDLPP--------------
----------------------RLDRNSKPTN----------------------------
------------------MPMRTQSQGRSAQERLINKTDSVLDMANYINATSHRANATSS
LE----------------------------------------------------------
--------------------RTQAKAGSYDSMSSYDSYNTNGNVAYPGSGLN--------
------TSTGRLGPNVPDDL----------------------------------------
----------------------KSSTIGVSSRPHDPYRFTRSTAIPVQETQT--RTDYAK
YSRTGDYKPV--PPSQSKTG-TYKPVPPPKPKNYRPPQQPIIQDE---NNGGNMYQHAKS
YSMGTSHMHNGAENGVNMQRNSGQYYYNISPAANRNMQNDAYSVNSNHT-----------
------------------------------HQHHASPASHSHSVSHSHPLSSPSMMSHSH
SNSSGQIGIAHSHNRNNNNNNVSMNGHSHSNSHSGISLQNSPSANNAHNRESSALDLAGS
REQRGSAFELYRKPLHHHNIRTMGMGMARGAFGSKGGVLEGPGGVTLIIPPGALPPNSHQ
EIYFSVTDPNGVELHNNT------------------------------------------
--------------------------------------------------RGHRSSISPP
MHNGESMLSPLVECGPKGLEFQNPVELRIPHKATPAHRLALKATDTENNSNADWLNVKLP
DPTSDHVIVRLDHF--------
>gi|47212396|emb|CAF91077.1|	Tetraodon nigroviridis
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
---------------NPVM-----------------------------------------
----------------------------------------------------EETVWEQY
TVTLQRDPKMGFGIAVSGGRDNPNEETGETSIVVSDVLQGGPA--DGLLFEKDRVIQVNA
ISMEGANHSFAVGTLRKCGKVAKITVKRPRKVPVNLL---NVPPSPDDRVFNTDYNDDYN
FD-PDRRSVYSGGRDHSAERDRGRGEYMDG------GYQSREHDYDRDYDR-------RE
RGRSRERDLSPGRHYRR--DGSRSRTLDRDFSPDRPHEYSPDRRYRSERTLDRG-DYSPD
RRYRSERAVDREYSPDRRYRSERALDQDYSPD-RRYRSERTLDRTNSPDLRHRDHSPSPT
AMPIPLPRPTRDVEP-LEKPLNVLLVKNRPNEEYGLRLGSQLFIKEM---TSTGLASRDG
NLKEGDIILKINGT-VTENLSLSDAGKLIEKSRGKLQLVVQRD-GRQVLVRLPPMEDSDS
E-----LDDISEIGSYRSYSP-------QEDRRAHHSDLSSHSSNEKLREKPRDLNFFHT
REDPSSRLAKMGA--MATPFKGLDRGDQPPLP--PEKEEPRSKTSPAVTSAPKLNA----
---SPKVPLKPSAEDL-----EVYGPG-----------------------------TVMV
RFPKGES----------VGLRLAGGND-VGIFIAGIQEDSAAEQEG-LHTGDQIMKYCYD
LTQVNNMDFRGMVREDAVLYLLEIPKGDDVTILVQSKPDGDHEILFHNHVYQNLYEDI--
-------------LASGRGD-------SFYIRTHFEYEKE-----APQSLPFTRGEIFKV
TDTLYDG---------KLGNWLAIRCDS---DSQLLEKGIIPNKSRAEQ-----MANVQN
A-------ARAALGND-RGD--------FWRLRGQRA----AKRKD-LRKSREDLSAIPV
T-TRFPAYERVVLREAGFKRPVVIFGPISDAVNEKLANDMPDDFVIAK-----------T
EPK-----------------------------DAGS-EKSSGVVRLNTIRQIIEQDRHAL
LDVTPKAVDTLNYTQWYPIVLFLNPDSKQGVKAMRNRLIPGSSRSSRKLYEQSVKLRKTC
SHLFTATIDLNSANDAWYGSVKDSIQEQQDRAVWVCEGKMDG--SDEDL--DLHDDRMSY
LSAMSADY--LSMDSRLTSDYDDTADEGGAYTDNELDEPVD---------E----PQTVS
AISRSSEPVYSDEVGAVP------------QPEPRTRMKKSGSKE---------------
----------------------MLNREPSPPP----------------------------
----------------------------------------------SFVPEPPKGRSQTH
HD----------------------------------------------------------
---------------------------ST--------RCSSSTISSDAITG---------
-----SKPLP------PPVA---------------------------HKPSLAR------
---------LGQTSEEQIT--EKERDS-----EDPA---NKSFLGKIKAFEK--MDHLAR
AQRMLELQEA--ENARLEIA-QKHPDIYAVPVKLQKSNINRPQPI-------GSSSNPEP
QAPYRPTYSE-SRG---HDDDEPE-YRKQLAEQAKKGYYS-PQKY---------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
--------------------------------------------------KDTEL-----
------------------------------------------------------------
----------------------
>gi|148227093|ref|NP_001079562.	Xenopus laevis
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-----------------ME-----------------------------------------
----------------------------------------------------EMTIWEQY
TATLIRDPRRGFGIAVSGGRDRPLGIDGDNSVIVSDVIRGGPA--DGRLQTRDRIVMVNG
VSMENVSSSFAIQTLKSCSKSANVTVKRPRKIQIPVSNSMHPASTYSSHTQKS---SEPV
FSDSSRREKDDGPDSPLPWRGRYESSKQEPPADTARGYEGDSSSGHSSQGSFTHSSCHAR
HRRGRTVGRDGINYARRKVGRE--------------------------------------
-----SGGSGSETGRRSRRRERGSDVMDSGSEARGYSSKRRETGSEVGGSGSEIGERYPN
GLELVSGFKRLPIQDVPAKPMKAVLVKRAENQEYGLKLGSQIFIKHI---TESGLAAQEK
ALQEGDLILKINGV-TSENMSLADTRRLIEKSRGKLTLTVLRD-NRQFLVNIPEVRDSES
EERSSSREDISEIGSDDSLPP------------------SEAPPPPPAHQQK------SS
SESDISASEENGLNGSEVVQKMENPVVKNAEHNEEAQVVSTYREESA-------------
---NPNNNLKEDLR-------AGYSPD-----------------------------ARLI
QFMKEKS----------IGLRLAGGND-VGIFVAAVQAGSPAEREG-IKEGDQILQ----
---VNGTSFHNLTREDAVQFLMGLPQNEDVIFLTQGKED--------------IYRKM--
-------------IKSSVGD-------SFYIRTHFDYESE-----APSGLSFTRGEIFHV
LDTMYRG---------KLGSWLAVRVAR---DLREMQKGIIPNGSRAEQ-----YASLET
V-----LKPQSNSGQ--RAE--------FWKLRGLRG------AKKLLKKSREDLTALSK
K-IKYPPYERVVLREASFKRPVVVMGPITDIAHQKLCADLPQEFEAAE-----------S
VTR-----------------------------DG----ETSKVIKLDIVKEIAGKNKHAL
LEITPTAVEHLNYMQFYPIVVFCNPENRQGVKAMRKWLIPDSRKSSRRLYAQAVKQRKNY
SHLFTATINLSGASDSWLRSLKEIIQTEQTKPIWTTEDKEIT--VTEPL------DLLDE
STAGVNDY--LSCDSRANSDYDETDAEGGAYTDQELEEEIQ-----------------EP
ALARSSEPVPDYQST---------------------------------------------
------------------------------------------------------------
----------------------------------------------YYRAQSPDEYPSKY
KD----------------------------------------------------------
-----------------------------------QSLPERDNFHGNKPC----------
------------------------------------------------------------
--------------------------------PEESQNQPQGQWSANAINSR-------E
YEHDALLKKF--NNARYSSS-EEEEDAWGGPATDL-------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
----------------------
>gi|50978966|ref|NP_001003204.1	Canis lupus
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------M-----------------------------------------
----------------------------------------------------EELIWEQY
TVTLQKDSKRGFGIAVSGGRDNPHFENGETSIVISDVLPGGPA--DGLLQENDRVVMVNG
TPMEDVLHSFAVQQLRKSGKIAAIVVKRPRKVQLAPPQG-SLPVDEDDRAFEV-MD---E
FDGRSARSGYSERSRRSSHGGRSRS-WEDS------PERGRPHERAWSQER--E----RS
RGRSLERGLDHDDDYRRPRERSRGRSLERGLDHD--DDYGRPGERSHGMSTDRGYDRGYD
RGY--DRGYDRTYSPEAEYGRRTQPDARHAGS-RSRSREHLRSRSPSPELRGRPDHAGQ-
-------------PD-SDRPIGVLLMKSKANEEYGLRLGSQIFIKQM---TRTALATKDG
NLHEGDIILKINGT-VTENMSLTDARKLIEKSRGKLQLVVLRD-SKQTLINIPSLNDSDS
E-----IEDISEIESNRSFSP--------EERRQQYSDYDYHSSNEKLKERP------NS
REDMQNRWSRMGA--TPTPFKSMGDIASVVGT--ENSKEPRYQEEPPA---PQPKA----
---APRTFLRPSPEDE-----AIYGPN-----------------------------TKMV
RFKKGDS----------VGLRLAGGND-VGIFVAGIQEGTSAEQEG-LQEGDQILK----
---VNTQDFRGLVREDAVLYLLEIPKGEMVTILAQSRAD--------------VYRDI--
-------------LACGRGD-------SFFIRSHFECEKE-----TPQSLAFSRGEVFRV
VDTLYDG---------KLGHWLAVRIG------NELEKGLIPNKSRAEQ-----MASVQN
A-------QRDNAGD--RAD--------FWRMRGQRS----GMKKN-LRKSREDLTAAVS
VSTKFPAYERVLLREAGFKRPVVLFGPIADIALEKLANELPDLFQTAK-----------T
EPK-----------------------------DAGS-EKSSGVVRLNTVRQIIEQDKHAL
LDVTPKAVDLLNYTQWFPIVIFFNPDSRQGVKTMRQRLNPTSNKSSRKLYDQANKLKKTC
AHLFTATINLNSANDSWFGSLKDTIQHQQGEAVWVSEGKMEG--MDDDP-----EDRMSY
LTAMGADY--LSCDSRLISDFEDTDGEGGAYTDNELDEPAE---------E----PL-VS
SITRSSEPVQHEESIRKP------------SPEPRAQMRRAASRD---------------
----------------------QL-RDSSPPP----------------------------
----------------------------------------------AFKPEPPKAKTQNR
EE----------------------------------------------------------
---------------------------SFDISRSHDYKSNPSAVAGNEVSGA--------
----STRSCP------PPIA---------------------------AKPSFGRSILKP-
-----STP-VPSPESEEVG---EGSEE-----QEGA---PKSVLGKVKIFEK--MDHKAR
LQRMQELQEA--QNARIEIA-QKHPDIYAVPIKTHKPDPGLSQHT--------SSRPPEP
QKGPSRLYQD-PRGSYGSDAEEEE-YRQQLSEHSKRGYYSQPSRY---------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
--------------------------------------------------RDTEL-----
------------------------------------------------------------
----------------------
>gi|74002970|ref|XP_545159.2|	Canis familiaris
MPVR----KQDTQRALHLLEEYRSKLSQTEDRQLRSSIERVINIFQSNLFQALIDIQEFY
EVTLL----------------------------------------------DNPKCIDRS
KQSEPIQPVNTWEISS------------------LPSTTV--TSETLPSSLSPSVEKYRY
QDEDTPPQEHISPQITNEVIGPELVHVSEKNLSEIENVHGFVSHSHIS----PIKPTEAV
PPSSPTVPVIPVLPVPAENTVILPTIPQANPPPVLVNTDSLETSTYVN---GTDADYEYE
EITLERGNS-GLGFSIAGGTDNPHIGD-DSSIFITKIIAGGAAAQDGRLRVNDCILRVNE
VDVRDVTHSKAVEALKEAGSIVRLYVKRRKPVSEKIMEI-KLIKGPKGLGFSI-------
------------------------------------------------------------
------------------------------------------------------------
-----AGGVGNQHIPG--------------------------------------------
--------------------------------------DNSIYVTKI---IEGGAAHKDG
KLQIGDKLLAVNSV-CLEEVTHEEAVTALKNTSDFVYLKVAKP-TSMYM-----------
------NDGYAPPDITNSSSQ----------------PVDNHVSPSSYLGHT--------
--------PASPARYSPVSKAMLGDDE---------------------------------
-----------------------ITRE-----------------------------PRKV
VLHRGSTG---------LGFNIVGGEDGEGIFISFILAGGPADLSGELRKGDRIIS----
---VNSVDLRTASHEQAAAALKN--AGQAVTIVAQYRPE--------------EYSRFEA
KIHDLREQMMNSSISSGSGSLRTSQKRSLYVRALFDYDKTKDSGLPSQGLNFKFGDILHV
INASDDE------------WWQARQVTP---DGESDEVGVIPSKRRVEKKERARLKTVKF
N--SKTRGDKGQSFNDKRKKNLFSRKFPFYKNKDQSEQETSDADQHITSNASDSESSYRG
QEEYVLSYEPVNQQEVNYTRPVIILGPMKDRINDDLISEFPDKFGSCVP--------HTT
RPKRDYEVDGRDYHFVTSREQMEKDIQEHKFIEAGQYNNHLYGTSVQSVREVAEKGKHCI
LDVSGNAIKRLQIAQLYPISIFIKPKSMENIMEMNKRL---TEEQARKTFERAMKLEQEF
TEHFTAIVQGDTLED-IYNQVKQIIEEQSGPYIWVP--------AKEKL-----------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
----------------------
>gi|45382517|ref|NP_990249.1|	Gallus gallus
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------M-----------------------------------------
----------------------------------------------------EELIWEQY
TVTLQKDSKRGFGIAVSGGRDNPHFENGETSIVISDVLPGGPA--DGLLQENDRVVIVNG
TPMENVPHSFAVQQLRKSGKVATIVVKRPRKVQAAALRK-NPSLDYEDRALEV-MDDHAE
FDGKSARSGYSERSWRSGNGGRSQS-WGNSLDQSYRDDQDREHNRSRGRSRGCSYSRDQS
RGRSIDRSLDQ--DYGR--DRSRGRSVDR------------------------------D
GGY--GQDYRRDYSPAS-YRHGSQPDPRYVREVRSLSRDRLHSRSPSPETRHQHEYLGP-
-------------QD-QNGPISVLLTKGKHNEEYGLRLGSQIFIKEM---TSTGLATKDG
NLHEGDIILKINGT-VTENMSLADARKLIEKSRGKLQLVVLRD-RKQTLLNIPSLNDSDS
E-----MDDISEIESNRSFSP--------QDDRLHHSDLDLHSSNEKLKEKT------NA
KDDPSNRMSRMGA--MPTPFKSTGDIATTAVTVVDANKEPKYQDDVAV---PQPKA----
---VTRTILKPSPEDE-----AIYGPN-----------------------------TKMV
RFKKGDS----------VGLRLAGGND-VGIFIAGIQEGTSADQEG-LQEGDQILK----
---VNAQDFRGIVREDAVLYLLEIPKGDTVTILAQSKYE--------------VYRDI--
-------------MACGRGD-------SFFIRSHFECEKE-----SPQSLAFTRGEIFRV
VDTLYDG---------KLGNWLAVRIG------NELEKGLIPNRSRAEQ-----MASVQN
A-------QKDGPSD--RAD--------FWRTRGQRS----GVKKN-LRKSREDLTAIVS
VGTKFPAYERVQLREAGFKRPVVIFGPIADVAMEKLSTDLPHLYQTAK-----------T
EPR-----------------------------DAGS-EKATGVVRLNTVRQIIEQDKHAL
LDVTPKAVDLLNYTQWFPIVVFFNPDSKQGVKTMRQRLCSTSNKSSRKLYEQANKLKKTC
SHLFTATINLNSANDSWYGSLKDTIQQQQGEAVWVSEGKVDG--MEDDA-----DDRMSY
LTAMGADY--LSCDSRLISDLEDTDGEGGAYTDNELDEPLD---------E----PR-IS
SVGRSSEPVHHEENIKKF------------SLEQRTPLRKAGSRE---------------
----------------------IL-REPSPPP----------------------------
----------------------------------------------AFKPEPPKGKLQNK
ED----------------------------------------------------------
---------------------------LYDFPKNYDSKPS-SIHVSSETSTV--------
----SAKAAP------PPVS---------------------------VKPTFGRPILRN-
-----TQPAVPSAEEEEEGKLEEEGSE-----QENT---PKSVLRKVKIFEE--MDHKAR
LQRMQELQEA--QNARIEIA-QKHPDIYAVPVKTQKSDQNWPQPI--------SCRPPEP
QKPPTRPYLE-DRGSCGSDGEEEEEYRRQLSDHSKKGYYGQPPRY---------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
--------------------------------------------------RDTEL-----
------------------------------------------------------------
----------------------
>gi|148709667|gb|EDL41613.1|	Mus musculus
-----------------------------------------MGLCTERDKMRYKKYIAIL
EAAV-----------------------------------------------GITPLNKRE
LLPESRRHVNLWQHP-------------------GARSPALLSSPCEWDWHPGYSSRPRY
SGGHRPVSTYSLLSQGPGM-----------------------------------------
----------------------------------------------------EEVIWEQY
TVTLQKDSKRGFGIAVSGGRDNPHFENGETSIVISDVLPGGPA--DGLLQENDRVVMVNG
TPMEDVLHSFAVQQLRKSGKIAAIVVKRPRKVQVAPLQG-SPPLSHDDRGFEV-IE---E
FDGRSFRSGYSERSRHSSHDMLSHS-WEGN------RERGRPHQRTQSRER--E----RS
RGRSLERGLDQ-EDYGRSRERSRGRSLERGLDRDF-VSRDHSRGRSIDRDYDRDYERSYH
EAY--EPDYGGGYSPS--YDRRAHPETRY--E-RSRSREHLRSRSPSPESRSRHEHKGQ-
-------------HD-PDRPIGVLLTKSKANEEYGLRLGSQIFIKEM---TRTGLATKDG
NLHEGDIILKINGT-VTENMSLTDARKLIEKSRGKLQLVVLRD-SKQTLINIPALNDSDS
E-----VEDISEIESNRSFSP--------EERRQQYSDQDYHSSTEKLKERP------SS
REETSGRLSRMGA--TPTPFKSTGDITAAGVT--EASREPRYQEEGPV---PQPRT----
---APRVFLRPSPEDE-----AIYGPN-----------------------------TKMV
RFKKGDS----------VGLRLAGGND-VGIFVAGIQEGTSAEQEG-LQEGDQILK----
---VNTQDFRGLVREDAVLYLLEIPKGETVTILAQSRAD--------------VYRDI--
-------------LACGRGD-------SFFIRSHFECEKE-----TPQSLAFTRGEVFRV
VDTLYDG---------KLGHWLAVRIG------NELEKGLIPNKSRAEQ-----MASVQN
A-------QRENAGD--RAD--------FWRMRGQRS--SGGVKKN-LRKSREDLAAAVS
VSTKFPAYEKVLLREAGFKRPVVLFGPIADIAMERLATELPDLFQTAK-----------T
EPK-----------------------------DAGS-EKSSGVVRLNTVRQIIEQDKHAL
LDVTPKAVDLLNYTQWFPIVIFFNPDSRQGVKTIRQRLSPTSNKSSRKLFDQANKLKKTC
SHLFTATINVNSANDGWFGSLKDSIQQQQNEAVWVSEGKMEG--MDDDA-----EDRMSY
LTAMGADY--LSCDSRLISDFEDTDGEGGAYTDNELEEPAE---------E----PL-VS
SITRSSEPVQHEENIRKS------------SPEPRAQMRRAASRD---------------
----------------------QL-RDASPPP----------------------------
----------------------------------------------AFKPEPPKARSQNR
ED----------------------------------------------------------
---------------------------SFDYS-----KSNLPATAGSEIPGG--------
----STKGYP------PPIA---------------------------AKPAFGRPILKP-
-----STP-VPMPESEEVG---ESTEE-----QEDA---PRSVLGRVKIFEK--MDHKAK
LQRMQELQEA--QNARIEIA-QKHPDIYAVPIKAPKPDAGLPPHM---------------
RGEPKVLMHS-ECC-----------FTTELHPTLPDLF----------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
----------------------
>gi|13634076|sp|Q9UDY2|ZO2_HUMA	Homo sapiens
------------------------------------------------------------
------------------------------------------------------------
-------------------------------------------------------MPVRG
DRGFPPRRELSGWLRAPGM-----------------------------------------
----------------------------------------------------EELIWEQY
TVTLQKDSKRGFGIAVSGGRDNPHFENGETSIVISDVLPGGPA--DGLLQENDRVVMVNG
TPMEDVLHSFAVQQLRKSGKVAAIVVKRPRKVQVAALQA-SPPLDQDDRAFEV-MD---E
FDGRSFRSGYSERSRLNSHGGRSRS-WEDS------PERGRPHERARSRER--DLSRDRS
RGRSLERGLDQ--DHARTRDRSRGRSLERGLDHDFGPSRDRDRDRSRGRSIDQDYERAYH
RAY--DPDYERAYSPE--YRRGARHDARSRGP-RSRSREHPHSRSPSPEPRGRPG-----
-------------------PIGVLLMKSRANEEYGLRLGSQIFVKEM---TRTGLATKDG
NLHEGDIILKINGT-VTENMSLTDARKLIEKSRGKLQLVVLRD-SQQTLINIPSLNDSDS
E-----IEDISEIESNRSFSP--------EERRHQYSDYDYHSSSEKLKERP------SS
REDTPSRLSRMGA--TPTPFKSTGDIAGTVVP--ETNKEPRYQEEPPA---PQPKA----
---APRTFLRPSPEDE-----AIYGPN-----------------------------TKMV
RFKKGDS----------VGLRLAGGND-VGIFVAGIQEGTSAEQEG-LQEGDQILK----
---VNTQDFRGLVREDAVLYLLEIPKGEMVTILAQSRAD--------------VYRDI--
-------------LACGRGD-------SFFIRSHFECEKE-----TPQSLAFTRGEVFRV
VDTLYDG---------KLGNWLAVRIG------NELEKGLIPNKSRAEQ-----MASVQN
A-------QRDNAGD--RAD--------FWRMRGQRS----GVKKN-LRKSREDLTAVVS
VSTKFPAYERVLLREAGFKRPVVLFGPIADIAMEKLANELPDWFQTAK-----------T
EPK-----------------------------DAGS-EKSTGVVRLNTVRQIIEQDKHAL
LDVTPKAVDLLNYTQWFPIVIFFNPDSRQGVKTMRQRLNPTSNKSSRKLFDQANKLKKTC
AHLFTATINLNSANDSWFGSLKDTIQHQQGEAVWVSEGKMEG--MDDDP-----EDRMSY
LTAMGADY--LSCDSRLISDFEDTDGEGGAYTDNELDEPAE---------E----PL-VS
SITRSSEPVQHEESIRKP------------SPEPRAQMRRAASSD---------------
----------------------QL-RDNSPPP----------------------------
----------------------------------------------AFKPEPPKAKTQNK
EE----------------------------------------------------------
---------------------------SYDFSKSYEYKSNPSAVAGNETPGA--------
----STKGYP------PPVA---------------------------AKPTFGRSILKP-
-----STP-IPPQEGEEVG---ESSEE-----QDNA---PKSVLGKVKIFEK--MDHKAR
LQRMQELQEA--QNARIEIA-QKHPDIYAVPIKTHKPDPGTPQHT--------SSRPPEP
QKAPSRPYQD-TRGSYGSDAEEEE-YRQQLSEHSKRGYYGQSARY---------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
--------------------------------------------------RDTEL-----
------------------------------------------------------------
----------------------
>gi|119913499|ref|XP_582218.3|	Bos taurus
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------LRSREEERISKPGAVS------------------TPVKHADD------------
------------------------------------------------------------
------------------------------------------------------------
------------HTPK--------------------------------------------
------------------------------------------------------------
---------------TVEEV------------------VVERN-EKQA----PNLPEPKP
V-----YAQVGQPDVDLPVSP------------------SDGVLPNSTHEDG--------
------------------------------------------------------------
----------------------ILRPS-----------------------------MKLV
KFRKGDS----------VGLRLAGGND-VGIFVAGVLEDSPAAKEG-LEEGDQILR----
---VNNVDFTNIIREEAVLFLLDLPKGEEVTILAQKKKD--------------VYRRI--
-------------VESDVGD-------SFYIRTHFEYEKE-----SPYGLSFNKGEVFRV
VDTLYNG---------KLGSWLAIRIGK---NHKEVERGIIPNKNRAEQ-----LASVQY
T------LPKTAGGD--RAD--------FWRFRGLRS-----SKRN-LRKSREDLSAQPV
Q-TKFPAYERVVLREAGFLRPVTIFGPIADVAREKLAREEPDIYQIAK-----------S
EPR-----------------------------DAGTDQRSSGIIRLHTIKQIIDQDKHAL
LDVTPNAVDRLNYAQWYPIVVFLNPDSKQGVKTMRMRLCPESRKSARKLYERSHKLRKNN
HHLFTTTINLNSMNDGWYGALKEAIQQQQNQLVWVSEGKADGA-TSDDL--DLHDDRLSY
LSAPGSEYSMYSTDSRHTSDYEDTDTEGGAYTDQELDETLN---------DEVGTPP-ES
AITRSSEPVREDSSGMHPDHQAYPPYSPQAQPQPGHRIDSPGFKTASQQKAEASSPGPYL
SPETNPAPSASAVNPHVDLTNVRL-EEPSPAPPSSDSPHADSLRAPGTEAAHVQLKGPEP
SLSSHVGPAKVYRKDPYPEEMMRQNHVLKQPAVVHPGQRPDKEQGLSYEPQPPYTERQAG
RELEQPAYRYDASSYPEQFARNYDHRLRYDDRLLTYEEQWPYYDDKQPYQPRP-------
--LDG-QPPAEPTERGYFPRFEEPVPLSYEGRAHYDPLPRTSTLRHEEPPAPAPGYDVHG
RYRPDVQPYSTAGPKVPPEPKQYLDQYPRSYEPAPAQGFPSRAGPGHYEPLHSTTLAPPL
GPSSQHKPEVPPTGTKPLPPPPAPAEE-----EEDPAMKPQSVLTRVKMFEN--------
-KRSASMENR--KDESHSTS-FKPPEVTSKPAGAPVPGPKAPAPSQLGEHDRAAHRIPEP
QRPHMKPPEDIVRANHYDPEEDEEYYRKQLSYFDRRSFEAKPPTHIPTSHLSEPTRPAHP
QSQPQFAGYSSKGKAAEAEAVDRSFGEKRYDPLQATPPPPPLPVQYSQGAQPSPNTALGL
HAHTKGAHGEGNAMSLDFQNSLVSKPDPPPSQNKPAAYRPAPREDAVQSGFYPQKSFPEK
APANGVEQTQKTVTPAYNRFTPKPYTSSARPFERKFESPKFNHNLLPNETAHKPDLSSKA
PASPKTLLKS---AQPPEFDSGVETLSVHTDNKLKYQVNSVSMGPRAVPVSPSAVEEDED
EDGHTVVATARGVFNSNGGVLSSIETGVSIIIPQGAIPEGVEQEIYFKVCRDNSILPPLD
KEKGETLLSPLVMCGPHGLKFLKPVELRLPHCASMTPDGWSFALKSSDSSSGDPKTWQNK
CLPGDPNYLVGANCVSVLIDHF
>gi|118783865|ref|XP_313293.3|	Anopheles gambiae
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-----MCFFFSFFPFQLQL-----------------------------------------
----------------------------------------------------ERTSWDYS
TVTLSRVTGYGFGIAVSGGRDNPHFANGDPSIAVSDVLKNGPA--EGQLQVNDRIISVNG
VSLENVEYATAVQVLRDSGNTVTLVVKRRVPNHSLM----HPLPGANMHGMAG-------
--------------------------------------PGGPS-----------------
------------------------------------------------------------
-----AGAMGVGMPAG---------------VVGMNSHQHQHSISSTGLGLGANNG----
----------------SQQQIKVIVTKANKKDDFGIVLGCRLFIREISSKTKDQLAANGY
SLQEGDLVTRIHNTNCNDSMSLKEAKKIIDGCKERLTLAVLRE-PNGIAGGYGGGAAGGG
GTASGMQSPVYSHTAQVSNCSNMDENYLNGTGGGSYSGQNLYVQPPTRPSAM----STLL
ADDKSNLTPRGRSRGPLTD-ISLQQLDRPSTP-----PGTVVDEPPRP---PPPRG----
---EDFYATRRQLMDE-----KPPTTE-----------------------------PRYI
TFQKEGS----------VGIRLTGGNE-VGIFVTAVQQNSPASAQG-LVPGDKILK----
---VNDMDMNGVTREEAVLFLLSLQ--DRIELIVQYCKE--------------EFDSI--
-------------TAQQRGD-------SFHIKTHFHCDAP-----TKGELSFKAGDVFRV
IDTLYNG---------VVGAWQVLRIGR---GHQELQRGVIPNKARAEE-----LATVQF
N-----ASKKELNASESRVS--------FFRRRRSTH----RRSKSLSRENWDDVVFSDA
I-SKFPAYERVVLRHPGFVRPVVIFGPVADIARERLMKDFADKY---------------T
APLQDD--------------------------DKGS-SKCGGIVRLSNIRDIMDRGKHAL
LDVTPNAVDRLNYAQFYPIVIFLKADTKHTIKQMRQGLPKSAHKSSKKLFEQCQKLERVW
SHVFSTTINLNDPDT-WYRKLRDSIDQQQSGAVWMSETKPVES-LSDDFLFPMTTSRLSY
ASSPESDLE-LSPGPSASLSLGNLPQLVKSSSDPSIATNQDNLDRDREL-GDGMPPPYTN
PYEHGPHSRRMTVDNKYG------------FSSSKNGIGGGPSMNPEDAIYGSSTSLPDL
PP--------------------RIDRASKPANAPGAPSTSGSSLPSRNSSSGGTLGRSAQ
ERLFGNGKQSSTDALHDPTSSAQDEYSSRNQLLGLGAGDKRPTLPPMVNGGTTAPGAASS
LE----------------------------------------------------------
------RNPNANTSLDRSGGGGGGANGSYDSVSSYDSYNTSSQLTAQNMRLG--------
-------------PNAPDDLKSVPNRNGAHAMGANVS----------GLSDYGRNPALNN
APSDMLLTTARSNYNVHETLTQRNSGDRTAGGMNMPQRPTNLVLDSPRKHIIETKTDYGK
YSRNNSASQA--DYSKPNKG-PSMIGSPGPPPGAMGANMGNGAPF--------KPVPPPK
PKNYRPPVGGSGSNGTGMHHSGQWDNGEPISPRSPDGFYYPPMASSHYH-----------
--------------------------QGMAHNVPSSPNNGGSHAPGMHPYNPYTVGNGAN
GGNGGPMYNGNANGSHSNGYNNGNAQYPYGNTYMHRGNGAGTHGIALHPSDRHALDLAGS
REQRGSAFELYRKPQLGTMVGHHHNIR---------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
----------------------
>gi|149719263|ref|XP_001491305.	Equus caballus
-----------------------------------------MGIFKSSLFQALLDIQEFY
EVTLLNSQKSCEQKIEEANQVAQKWEKTSLLASYHDNLQKSAELVGCSGPKENASCIEQS
KDNQCFEN-ATDKKTSQ-------------NQGRCPAQNC--SVEAPGWMPVHHCTKYRY
QDEDA-PHDHSLPRLTHEVRGPELVHVSEKNLSQIENVHGYVLQSHIS----PLK-----
----------------------------ASPAPIIVNTDTLDTIPYVN---GTEIEYEFE
EITLERGNS-GLGFSIAGGTDNPHIGD-DPGIFITKIIPGGAAAEDGRLRVNDCILRVNE
VDVSEVSHSKAVEALKEAGSIVRLYVRRRRPILETVVEI-KLFKGPKGLGFSI-------
------------------------------------------------------------
------------------------------------------------------------
-----AGGVGNQHIPG--------------------------------------------
--------------------------------------DNSIYVTKI---IDGGAAQKDG
RLQVGDRLLMVNNY-SLEEVTHEEAVAILKNTSDVVYLKVGKP-TTIYM-----------
------TDPYGPPDITHSYSP----------------PMENHLLSGNN----------GT
LEYKTSLPPISPGRYSPIPKHMLVEDDYTRPPEPVYSTVNKLCDKPASPRHYSPVE----
---CDKSFLLSAPYPH---YHLGLLPDSEMTSHSQHSTATRQPSVTLQRAISLEGEPRKV
VLHKGSTG---------LGFNIVGGEDGEGIFVSFILAGGPADLSGELQRGDQILS----
---VNGIDLRGASHEQAAAALKG--AGQTVTIIAQYQPE--------------DYARFEA
KIHDLREQMMNHSMSSGSGSLRTNQKRSLYVRAMFDYDKSKDSGLPSQGLSFKYGDILHV
INASDDE------------WWQARRVTL---EGDSEEMGVIPSKRRVERKERARLKTVKF
NAKPGVIDSKGSFNDKRKKSFIFSRKFPFYKNKEQSE-----QETSDPERGQEDFIL---
------SYEPVTRQEINYTRPVIILGPMKDRINDDLISEFPDKFGSCVP--------HTT
RPKRDYEVDGRDYHFVISREQMEKDIQEHKFIEAGQYNDNLYGTSVQSVRFVAERGKHCI
LDVSGNAIKRLQVAQLYPIAIFIKPKSLEPLMEMNKRL---TEEQAKKTYDRAIKLEQEF
GEYFTAIVQGDTLED-IYNQCKLVIEEQSGPFIWIP--------SKEKL-----------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
----------------------
>gi|114656061|ref|XP_001163001.	Pan troglodytes
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
--MTHSLRSRDEERISKPGAVS------------------TPVKHADD------------
------------------------------------------------------------
------------------------------------------------------------
------------HTPK--------------------------------------------
------------------------------------------------------------
---------------TVEEVT------------------VERN-EKQT----PSLPEPKP
V-----YAQVGQPDVDLPVSP------------------SDGVLPNSTHEDG--------
------------------------------------------------------------
----------------------ILRPS-----------------------------MKLV
KFRKGDS----------VGLRLAGGND-VGIFVAGVLEDSPAAKEG-LEEGDQILR----
---VNNVDFTNIIREEAVLFLLDLPKGEEVTILAQKKKD--------------VYRRI--
-------------VESDVGD-------SFYIRTHFEYEKE-----SPYGLSFNKGEVFRV
VDTLYNG---------KLGSWLAIRIGK---NHKEVERGIIPNKNRAEQ-----LASVQY
T------LPKTAGGD--RAD--------FWRFRGLRS-----SKRN-LRKSREDLSAQPV
Q-TKFPAYERVVLREAGFLRPVTIFGPIADVAREKLAREEPDIYQIAK-----------S
EPR-----------------------------DAGTDQRSSGIIRLHTIKQIIDQDKHAL
LDVTPNAVDRLNYAQWYPIVVFLNPDSKQGVKTMRMRLCPESRKSARKLYERSHKLRKNN
HHLFTTTINLNSMNDGWYGALKEAIQQQQNQLVWVSEGKADGA-TSDDL--DLHDDRLSY
LSAPGSEYSMYSTDSRHTSDYEDTDTEGGAYTDQELDETLN---------DEVGTPP-ES
AITRSSEPVREDSSGMHHENQTYPPYSPQAQPQPIHRIDSPGFKPASQQKAEASSPVPYL
SPETNPASSTSAVNHNVNLTNVRL-EEPTPAPSTSYSPQADSLRTPSTEAAHIMLRDQEP
SLSSHVDPTKVYRKDPYPEEMMRQNHVLKQPAVSHPGHRPDKEPNLTYEPQLPYVEKQAS
RDLEQPTYRYESSSYTDQFSRNYEHRLRYEDRVPMYEEQWSYYDDKQPYPSRPPFDNQHS
QDLDSRQHPEESSERGYFPRFEEPAPLSYDSRPRYEQAPRASALRHEEQPAP--GYDTHG
RLRPEAQPHPSAGPK-PAESKQYFEQYSRSYEQVPPQGFTSRAG--HFEPLHGAAAVPPL
IPSSQHKPEALPSNTKPLPPPPTQTEE-----EEDPAMKPQSVLTRVKMFEN--------
-KRSASLETK--KDVNDTGS-FKPPEVASKPSGAPIIGPKPTSQNQFSEHDKTLYRIPEP
QKPQLKPPEDIVRSNHYDPEEDEEYYRKQLSYFDRRSFENKPPAHIAASHLSEPAKPAHS
QNQSNFSSYSSKGKPPEADGVDRSFGEKRYEPIQATPPPPPLPSQYAQPSQPV--TSASL
HIHSKGAHGEGNSVSLDFQNSLVSKPDPPPSQNKPATFRPPNREDTAQPAFYPQKSFPDK
APVNGTEQTQKTVTPAYNRFTPKPYTSSARPFERKFESPKFNHNLLPSETAHKPDLSSKT
PTSPKTLVKSHSLAQPPEFDSGVETFSIHAE-KPKYQINNISTVPKAIPVSPSAVEEDED
EDGHTVVATARGIFNSNGGVLSSIETGVSIIIPQGAIPEGVEQEIYFKVCRDNSILPPLD
KEKGETLLSPLVMCGPHGLKFLKPVELRLPHCASMTPDGWSFALKSSDSSSGDPKTWQNK
CLPGDPNYLVGANCVSVLIDHF
>gi|149062607|gb|EDM13030.1|	Rattus norvegicus
-----------------------------------------MGLYTEKDKMRYKKYMAIL
EAAV-----------------------------------------------GITPLNKRE
LLPESRRHVNLWQHP-------------------GARSPALLSSPCQWDWHPGYSSRPKH
SAAHRPVSTYSLLSQGPGM-----------------------------------------
----------------------------------------------------EEVIWEQY
TVTLQKDSKRGFGIAVSGGRDNPHFENGETSIVISDVLPGGPA--DGLLQENDRVVMVNG
TPMEDVLHSFAVQQLRKSGKIAAIVVKRPRKVQVAPLQG-SPPLSHDDRGFEM-MD---E
FDGRSFRSGYSERSRHSSHDMLSHS-WEDS------RERGRPHQRAQSRER--E----RS
RGRSLERGLDH-EDYGRSHERSRGRSLERGLDRDF-VSRDYSRGRSIDRDYDRDYERSYH
QAY--EPDYEGRYSPS--YDRRAHPETRY--E-RSRSREHLRSRSPTPESRSRQEHKGQ-
-------------HD-PDRPIGVLLTKSKANEEYGLRLGSQIFIKEM---TRTGLATKDG
NLHEGDIILKINGT-VTENMSLTDARKLIEKSRGKLQLVVLRD-SKQTLINIPSLNDSDS
E-----VEDISEIESNRSFSP--------EERRQQYSDQEYHSSTEKLKERP------SS
REETSGRMSRMGA--TPTPFKSTGDITAAGVT--EANKEPRSQEESPV---PQPRT----
---ASRVFLRPSPEDE-----AIYGPN-----------------------------TKMV
KFKKGDS----------VGLRLAGGND-VGIFVAGIQEGTSAEQEG-LQEGDQILK----
---VNTQDFRGLVREDAVLYLLEIPKGETVTILAQSRAD--------------VYRDI--
-------------LACGRGD-------SFFIRSHFECEKE-----TPQSLAFTRGEVFRV
VDTLYDG---------KLGHWLAVRIG------NELEKGLIPNKSRAEQ-----MASVQN
A-------QRENAGD--RAD--------FWRMRGQRS----GVKKN-IRKSREDLAAAVS
VSTKFPAYEKVLLREAGFKRPVVLFGPIADIAMERLTTELPDLFQTAK-----------T
EPK-----------------------------DAGS-EKSSGVVRLNTVRQIIEQDKHAL
LDVTPKAVDLLNYTQWFPIVIFFNPDSRQGIKTIRQRLNPTSNKSSRKLFDQANKLKKTC
SHLFTATINVNSANDGWFGSLKDSIQQQQNEAVWVSEGKMEG--MDDDA-----EDRMSY
LTAMGADY--LSCDSRLISDFEDTDGEGGAYTDNELDEPAE---------E----PL-VS
SITRSSEPVQHEESIRKP------------SPEPRAQMRRAASRD---------------
----------------------QL-RDGSPPP----------------------------
----------------------------------------------AFKPEPPKVRNQNR
ED----------------------------------------------------------
---------------------------SFNYS-----KSNLSAMAGSEIPGG--------
----STKGCP------PPIA---------------------------VKPAFGRSILKP-
-----STP-VPMPESEEVG---ESTEE-----QEEA---PKSVLGRVKIFEK--MDHKAK
LQRMQELQEA--QNARIEIA-QKHPDIYAVPIKAPKPDAGLPQHM---------------
RGG----IQD-PHA-----------FRVLLHR----------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
----------------------
>gi|109131117|ref|XP_001085782.	Macaca mulatta
--------------MYVILPPFPRQAEPGEAPASSLPLGLGPGATTGDTEPPVLEGEPWV
RGSV-----------------------------------------GAEAPGRPPGPRPRS
ARAPPRVPPPSWSEQCECAREPGGGGGGGGGGGGVETGVGWGVRAAGGSAMHKHQHCCKC
PECYEVTRLAALRRLEPPGYGDWQVPDPYGPGGGNGASAGYGGYSSQTLPSQAGATPTPR
TKAKLIPTGRDVGPVPPKPVPGKSTPKLNGSGPSWWPECTCTNRDWYEQVNGSDGMFKYE
EIVLERGNS-GLGFSIAGGIDNPHVPD-DPGIFITKIIPGGAAAMDGRLGVNDCVLRVNE
VDVSEVVHSRAVEALKEAGPVVRLVVRRRQPPPETIMEV-NLLKGPKGLGFSI-------
------------------------------------------------------------
------------------------------------------------------------
-----AGGIGNQHIPG--------------------------------------------
--------------------------------------DNSIYITKI---IEGGAAQKDG
RLQIGDRLLAVNNT-NLQDVRHEEAVASLKNTSDMVYLKVAKP-GSLHL-----------
------NDMYAPPDYASTFTA----------------LADNHISHNSSLGYL---GAVES
KVSYPAPPQVPPTRYSPIPRHMLAEED---------------------------------
-----------------------FTRE-----------------------------PRKI
ILHKGSTG---------LGFNIVGGEDGEGIFVSFILAGGPADLSGELRRGDRILS----
---VNGVNLRNATHEQAAAALKR--AGQSVTIVAQYRPE--------------EYSRFES
KIHDLREQMMNSSMSSGSGSLRTSEKRSLYVRALFDYDRTRDSCLPSQGLSFSYGDILHV
INASDDE------------WWQARLVTP---HGESEQIGVIPSKKRVEKKERARLKTVKF
HARTGMIESNRDFPGL-SDD--------YYGAKNL--------------KGQEDAIL---
------SYEPVTRQEIHYARPVIILGPMKDRVNDDLISEFPHKFGSCVP--------HTT
RPRRDNEVDGQDYHFVVSREQMEKDIQDNKFIEAGQFNDNLYGTSIQSVRAVAERGKHCI
LDVSGNAIKRLQQAQLYPIAIFIKPKSIEALMEMNRRQ---TYEQANKIYDKAMKLEQEF
GEYFTAIVQGDSLEE-IYNKIKQIIEDQSGHYIWVP--------SPEKL-----------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
----------------------
>gi|28573161|ref|NP_476697.3|	Drosophila melanogaster
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-------MKFPDYVPNNMLVG---------------------------------------
----------------------------------------------------DRTTWEYH
TVAVTRVPGYGFGIAVSGGRDNPHFANGDPSIAVSDVLKGGPA--EDRLQVNDRIISVNG
VSLENVEYATAVQVLRDSGNTVQLVVKRRVPLN--PINAAGAVQHQHSHSLSS-------
------------------------------------------------------------
------------------------------------------------------------
VGLMANGSGGVAPTPI-------------------------TSLSQPNSLNSSLVQNAS-
----------------SGQPIKVTLTKGGKKDDYGVVLGCRLFVKEISSKAREQLNANGY
SLQEGDIITRIHNTNCGDTMSLKEAKKIIDGCKERLNLVVLRDITNQTAVSQLNLNNSAS
HQASGNIYATHQPQVSGCSSSNNNLEDPYLPGGASYSSQNLYVQPPTRTSNGPNINGNGL
NDEKSNLTPRGRSRGPIMDGVSLQQLDRPVTP--TRGRSAAIDEPPRP---PPPRGSSGG
AAQEDFYSSRRQLYEE------RQSAE-----------------------------PRFI
SFQKEGS----------VGIRLTGGNE-AGIFVTAVQPGSPASLQG-LMPGDKILK----
---VNDMDMNGVTREEAVLFLLSLQ--DRIDLIVQYCKE--------------EYDEV--
-------------VTNQRGD-------SFHIKTHFHCDNP-----SKGEMAFKAGDVFRV
IDTLHNG---------VVGSWQVLKIGR---GHQEMQRGVIPNKSRAEE-----LATAQF
N-----ATKKEMNANESRGN--------FFRRRRSTH----RRSKSLSRENWDDVVFSDS
I-SKFPAYERVVLRHPGFVRPVVLFGPVSDLARERLAKDFPDKF---------------S
TPLQDDD-------------------------KSAATSGKCRIVRLSNIRDVMDRGKHAL
LDITPNAVDRLNYAQFYPVVIFLKTDSKHVIKQLRHGLPKAAHKSSKKLLEQCQKLERVW
SHIFSTQIALSDEES-WYRKLRDSIDLQQSGAVWMSESKPVES-LSDDFLFPMTTSRLSY
ASSPESDLE-LSPGPSASLSLGNLPQLVKASSDPSIATNQDNLDRDRDIIGEGLPPPYTV
PYDHA-VPANPNRRQTMDSSKYSIYGTNVPPQQQQPGVGGDTAAVRPQSLYGINA--PDL
PP--------------------RIDRQSKPGDIPLNTSGS--------SSRNGTLGRSAQ
ERLFGKAVVQ---------DDVQAEYITRNALVGSGAAET------LDRQQQQQQQTHAS
LE----------------------------------------------------------
-----RQARLNAQLKANGVGAGGGGASTYDSVSSYDSYNNT--------QMA--------
-----MQNLGRLGPNAPDDLKSVPNANGRPLPPTGQS--HEYG----RTPHDHRSFGGPN
DLNRQSSPGRPHYHDMNASRNIDPRNG----TPQRPSNLGLESSPRKPLVET--KTDYGK
YSRNNSVTQA--DYTKLPKT-APHGVVPPPNVSNGQGQMNGSGTPSSNGSGPFKPVPPPK
PKNYRPPVQSGGSSGSG--GTTPWENGDSGSPRSPNGFYYPPTPSHHHY-----------
---------------------GQQA--TPGSPSNGHMQPPPPQQQQPTYGGSNGNYGQAP
PPQSYPQANGYNGNGHHYNGGSGTGPYIAPHRGMPPPIGNLP----PHTPERHALDLAGS
REQRGSAFELYRKPQIGATAGHHHNMR---------------------------------
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>gi|125777140|ref|XP_001359509.	Drosophila pseudoobscura
-------------------------------REKENDRNRRAVSYGGGEMPSSVQSATIP
RAAP-----------------------------------------------RRVALMKEP
PPPPPPKP--------------------------QLSSKASLQSTDSSSTCLASSKYPQS
EYNLIQKIDSNSTLTAPAQYQPQNFYANTGTMASSNGYGSLLCHASSTASPLAVRKRDKL
LHRFSDAATLGRKLKKKKNTN-------RTCRSMTEAIEMLADPVIEDEFFGDRTTWEYH
TVSVTRVPGYGFGIAVSGGRDNPHFANGDPSIAVSDVLKGGPA--EDRLQVNDRIISVNG
VSLENVEYATAVQVLRDSGNTVTLVVKRRVPLNTVNAGLPGGVQHQHQHSHSL-------
------------------------------------SSMGQMV-----------------
------------------------------------------------------------
-----ANGNGGGVLPG---------------GVGQPSGAVMSSLSQPNSLNSSLVQNAS-
----------------GGQPIKVTLTKGNKKDDYGVVLGCRLFVKEISSKAREQLNANGY
SLQEGDIITRIHNTNCGDTMSLKEAKKIIDGCKERLNLVVLRDITNQAAVSQMNLNNSGH
HQQSS-SNIYASHQAQVSGCS-NNLEDAYLPGGASYSSQNLYVQPPTRTSNGPSLNGNGL
NEEKSNLTPRGRSRGPLMDGVSLQQLDRPVSPTNGGRGRSGVEEPPRP---PPPRGTSGG
AAQEDFYSSRRQLYEE------RQSAE-----------------------------PRFI
SFQKEGS----------VGIRLTGGNE-AGIFVTAVQPGSPASLQG-LMPGDKILK----
---VNDMDMNGVTREEAVLFLLSLQ--DRIDLIVQYCKE--------------EYDEV--
-------------VTNQRGD-------SFHIKTHFHCDNP-----SKGEMAFKAGDVFRV
IDTLHNG---------VVGSWQVLKIGR---GHQEMQRGVIPNKSRAEE-----LATAQF
N-----ATKKEMNANESRGN--------FFRRRRSTH----RRSKSLSRENWDDVVFSDS
I-SKFPAYERVVLRHPGFVRPVVLFGPVSDLARERLAKDFPDKF---------------S
TPLQDD--------------------------DKSAASGKCRIVRLSNIRDVMDRGKHAL
LDITPNAVDRLNYAQFYPVVIFLKTDSKHVIKQLRHGLPKAAHKSSKKLLEQCQKLERVW
SHIFSTQIVLNDEES-WYRKLRDSIDLQQSGAVWMSESK-----VSLPY-----------
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>gi|149633621|ref|XP_001512806.	Ornithorhynchus anatinus
MPRSLDSIPQDTQRALLLLEEYRSKLSQTEDRQLRNSIERVINIFQSNLFQALIDIQEFY
EVTLL----------------------------------------------DNPKCIDHS
KPSEPLEPVNTWDFSS------------------LPSTTV--TSDTLPSSLSPGLEKYKY
QDEDTPPQEHSSPHISNEVTGPELVHISEKNLSEIENVHGFVSHSHIS----PLKPTEAV
PPSPPIVPVIPVLPAPAENTVIPPTTAQANPPPVLVNTDSLETPAYVN---GTDADYEYE
EITLERGNS-GLGFSIAGGTDNPHIGD-DSSIFITKIIAGGAAAQDGRLRVNDCILRVNE
VDVRDVTHSKAVEALKEAGSIVRLYVKRRKPVTEKIMEI-KLVKGPKGLGFSI-------
------------------------------------------------------------
------------------------------------------------------------
-----AGGVGNQHIPG--------------------------------------------
--------------------------------------DNSIYVTKI---IEGGAAHKDG
KLQIGDKLLAVNSV-CLEEVTHEEAVTALKNTSDFVYLKVAKP-TTMY------------
------KQSICPTRYPNSYSQ----------------PVDNHVSPSTYLGQT--------
--------PTSPSRYSPVSKGMLGDDE---------------------------------
-----------------------ITRE-----------------------------PRKV
VLHRGSTG---------LGFNIVGGEDGEGIFISFILAGGPADLSGELRKGDRIIS----
---VNSVDLRTATHEQAAAALKN--AGQAVTIVAQYRPE--------------EYSRFEA
KIHDLREQMMNSSISSGSGSLRTSQKRSLYVRALFDYDKTKDSGLPSQGLNFRFGDILHV
INASDDE------------WWQARQVTP---DGESDEVGVIPSKRRVEKKERARLKTVKF
N--SKTRGDKGQSFNDKRKKNLFSRKFPFYKNKDQSEQETSDVDQHITSNASDSESSYRG
QEEYVLSYEPVNQQEVSYTRPVIILGPMKDRINDDLISEFPDKFGSCVP--------HTT
RPKRDYEVDGRDYHFVTSREQMEKDIQDHKFIEAGQYNNHLYGTSVQSVREVAEKGKHCI
LDVSGNAIKRLQIAQLYPISVFIKPKSVENIMEMNKRL---QEEQARKTFERAMKLEQEF
TEHFTAIVQGDTLEE-IYNQVKQIIEEQSGSYIWVP--------AKEKL-----------
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>gi|109480163|ref|XP_234924.4|	Rattus norvegicus
------------------------------------------------------------
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-----------------ME-----------------------------------------
----------------------------------------------------ELTIWEQH
TATLYKDPRRGFGIAVSGGHDRAGG-----PVVVSDVVPGGPA--EGRLQTGDHIVMVNG
VSVENVTSAFAIQILKTCTKTANITVKRPRRVQLPATKA-SPASGHQLSDQEE-------
------------------------------------ADH---------------------
------------------------------------------------------------
-----GRGYEGDSSSG---------SGRSWGERSRRSRAGRRVRMGSHGRRSSCGGSEAN
GLDLVSGYKRLPKQDVLMRPLKSVLVKRRNSEEFGVKLGSQIFIKHI---TESGLAARNR
GLQEGDLILQINGV-SSANLSLSDTRRLIEKSEGQLTLLVLRD-SGQFLVNIPPAVSDSD
SSL---MEDISDLTSELSQAP------------------PSHIPPPPLKSRR-------S
PEDSQTDSPVE----TPQPQRRERSVDSRAIAEPESPGESRYD-----------------
---IYRVPSRQSLEDR------GYSPD-----------------------------TRVV
RFPKGVS----------IGLRLAGGND-VGIFVSGVQAGSPADGQG-IQEGDEILQ----
---VNDMPFRNLTREEAVQFLLGLPAGEDVELVIQSKQD--------------IFRKM--
-------------VQSRVGD-------SFYIRTHFELEPS-----PPYGLGFTRGDVFHV
VDTLYRGSGSGHGHSSHGGLWLAARMGR---DLREQERGVIPNQSRAEQ-----LASLEA
AQRAAGLGPGASTGSNPRAE--------FWRLRGLRR----GAKKTMTQRSREDLSALTR
Q-GHYPPYERVVLREASFKRPVVILGPVADIAMKRLTTEVPEQFEIAE-----------S
VSR-----------------------------TD----SPSKIIKLDTVRVIAERDKHAL
LDVTPSAIERLNYVQYYPVVIFCAPESRSALKALREWLAPASRRSSRRLYAQAQKLQKHS
GHLFTATIPLNGTSDSWYQEVKAVIQQQQARPIWTAEDQLNG--SSEDL-----DLPGHG
LAASSGD---LSCDSRANSDYEDTDGE-GTYTDRE-GEPQD---------FDEEAPP--T
ALARSSEPVWVDDHQGLM------------------GHGRIAAAE---------------
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-----------------------------------------------VQADSHYTPDQRR
QD----------------------------------------------------------
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---------------------------------------------SMRTYKH--EALRKK
FTRARDIESS--DEEGYDWG-PATDL----------------------------------
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