>gi|118097635|ref|XP_001234292.	Gallus gallus
------------------------------------------------------------
------------------------------------------------------------
----------------MSSEDREAQEDELLALASIYDEDEFK------------------
-------------------------------RAESAQGGETRICLELPQNFRVFVSGN--
--STEGPQSS-GFECTVC------------------------------FLPPLVLNFELP
PDYPSTSPPAFTL-S--------------------------------------SKWLSPA
QLSALC---------------------KHLDNLWEENRGCVVLFAWMQFLKEETLSYLNI
SSPYE--LKMC-------------------------------------------------
---------------------------------QQGNTQGGTPSVHQDAED---------
----CGAAMGCAAAEEEIDERAVQDVESL--------SSLIREILDFDQAQRRKCFNSKM
YLCNICFCEKLGTECMYFTECSHVYCKACLKDYFEIQI-RDGQVHCLNCPEPK--CSSVA
TPGQVKEL---VGEQLFARYDRLLLQSTLDLMADVVYCPRPGCQTPV-MQEPGCT-----
-MGICSCCNYAF-------CT--LCKMTY-----------HGVSPCKITAEKLMD-----
--------------LRNEYLEADEATKRFLEQRYGKRVIQKA-----LEEMESKEW--LE
KNSKAC-----------------PCCSTPIEKLDGCNK----MTCTG--CM------QYF
CWLCMAS-LSRVNPYKH-------------------------------------------
---------------------FNDPSSPCFDRLFQAMQ----------------------
------------------------------------------------------------
--------------------------------------------------IDGEF-----
-----------------------------------------WEDEN--------------
--------------------------------------------
>gi|48138658|ref|XP_396912.1|	Apis mellifera
------------------------------------------------------------
------------------------------------------------------------
----------------MDSEEET-YDDVD-------------------------------
-------------------------------SGNESSGDDV-------------------
--DFAMEIEA-GNPRERS------------------------------------------
---TDVDDYPFEV-L--------------------------------------STEEIVQ
HMVDSI---------------------KEVNTVVEIPATTTRILLNHFKWDKE-------
--------KLM-------------------------------------------------
---------------------------------ERFYDGDQEKLFAEAR-----------
----------------------VVNPFRK--------GPLINRNQSSQSSLSRRTSTNGT
EECGICFTIQPS-AMMTGLECGHRFCTGCWGEYLTTKIMEEGVGQTIACAAHA--CDILV
DDASVMRL--VKDSKVKLKYQHLITNSFVECNRLLRWCPSPDCNNAIKVQYVEAR-----
-PVTCK-CGHTF-------CF--HCGENW-----------HDPVKCHLLRKW--------
--------------------------------------IKKC-----DDDSETSNW--IA
ANTKEC-----------------PKCNVTIEKDGGCNH----MVCKNQNCK------TDF
CWVCLGP-WEPHGSSWYNCNRYDEEEAKAARDAQEKSRSALQRYLFYC------------
-----------NRYI------NHMQSLKFENKLYASVKEKMEEM------QQHN-MSWIE
VQFLKKAVDILCSCRQTLMYTYVFAYYVRKNNQSVIFEDNQKDLEGTTERLSEYLERDIT
SENLAD----------------------------------------IKQKVQDKYRYCD-
--SRRKVLLEHVHEGYEKD----------W-----------WDYVE--------------
--------------------------------------------
>gi|91076172|ref|XP_971560.1|	Tribolium castaneum
------------------------------------------------------------
-----------------------------------------------------------M
ASARYGRIRASLLSVVMDSEEDT-YDNVD-------------------------------
-------------------------------SGNESSGDDV-------------------
--DFAMEVEV-TGHREKQ------------------------------------------
---TDVDDYPYEV-L--------------------------------------STEEIVQ
HMVDSI---------------------KEVNSVVEISTTTTRILLNHFRWDKE-------
--------KLM-------------------------------------------------
---------------------------------ERFYDGDQDKLFSEAR-----------
----------------------VINPFNK-------------------YSNKVKKTSNGT
EECEICFMTLPS-SHMTGLECEHKFCTHCWCEYLTTKIMEEGVGQTIACAAYG--CDILV
DDATVMKL--VKDSKVKLKYQHLITNSFVECNRLLRWCPSPDCSNAIKVQYVEPH-----
-RVTCK-CNHTF-------CF--ACGENW-----------HDPVKCHLLKKW--------
--------------------------------------IKKC-----DDDSETSNW--IA
ANTKEC-----------------PKCNVTIEKDGGCNH----MVCKNQNCK------ADF
CWVCLGP-WEPHGSSWYNCNRYDEDEAKAARDAQEKSRSALQRYLFYC------------
-----------NRYM------NHMASLKFEHKLYASVKEKMEEM------QHHN-MSWIE
VQFLKRAVDILCQCRQTLMYTYVFAYYLQKNNQSVIFEDNQKDLESATETLSEYLERDIT
SENLAD----------------------------------------IKQKVQDKYRYCD-
--SRRKVLLEHVHEGYEKE----------W-----------WDYNE--------------
--------------------------------------------
>gi|47225863|emb|CAF98343.1|	Tetraodon nigroviridis
------------------------------------------------------------
------------------------------------------------------------
----------------MDSDEGYNYEFDDEEECSDDSAEEEPE-----------------
---------------DDTLELGEVELVDPVVAGGERDECGDTWRRWPWSRRGGRGGLPFR
GFDCRANPTA-YGGVHQG---------------------GQRGHSGRYFGVSVSGKTGVQ
VWVKLQQAFEFSLAV--------------------------------------SRQSTLA
YLLEVCIFNTRLQFITVFVSEGIPGTRVLQADVANNPVTITRILLSHFNWDKE-------
--------KLM-------------------------------------------------
---------------------------------ERYFDGNLDKLFSECH-----------
----------------------VINPSKK----------------PRNRPPINTRSSAQD
MPCQICYLNFPN-SYFTGLECGHKFCMQCWGDYLTTKIIEEGMGQTISCPAHS--CDILV
DDNTVMRL--ITDSKVKLKYHHLITNSFVECNRLLKWCPAPDCHHVVKVQYPDAK-----
-PVRCK-CGRQF-------CF--NCGENW-----------HDPVKCKWLRKW--------
--------------------------------------IKKC-----DDDSETSNW--IA
ANTKEC-----------------PKCHVTIEKDGGCNH----MVCRNQNCK------AEF
CWVCLGP-WEPHGSAWYNCNRYNEDDAKAARDAQERSRAALQRYLFYC------------
-----------NRYM------NHMQSLRFEHKLYAQVKQKMEEM------QQHN-MSWIE
VQFLKKAVDVLCQCRSTLMFTYVFAFYLKKNNQSIIFENNQADLENATEVLSGYLERDIS
QDSLQD----------------------------------------IKQKVQDKYRYCE-
--SRRRVLLQHVHEGYEKD----------L-----------WEYIED-------------
--------------------------------------------
>gi|110617782|gb|ABG78607.1|	Gibberella zeae
------------------------------------------------------------
------------------------------------------------------------
----------------MDSDEEYMSALSTDDEIMQDDSGDEI------------------
-------------------------------SAGDDFDDEEFDEPDP-------------
--DFGLAKDV-EKKKRAA------------------------------------------
------HVVSYKV-Y--------------------------------------EPSDIQS
QQDEMI---------------------GEVNMILDMQKEDAAILLRHFRWNKE-------
--------RLL-------------------------------------------------
---------------------------------EDYMDRPEKVMEAAGLSS---------
----------------------TTSSSPK-------------------------LEVIPG
FVCDICCEDDDG-LESFAMKCGHRYCVDCYRHYLTQKIREEGEAARIQCPSDG--CGRIL
DSASL-DV--LVTPALAGRYQELLNRTYVEDKDNFKWCPAPDCPNALECGVKKKDLGRIV
PTVECR-CGFRF-------CF--GCPNPD-----------HQPAPCDLVKKW--------
--------------------------------------LKKC-----ADDSETANW--IS
ANTKEC-----------------PKCNSTIEKNGGCNH----MTCRK--CK------YEF
CWMCMGL-WSEHGTSWYNCNRYEEKSGSEARDAQAKSRTSLERYLHYY------------
-----------NRYA------NHEQSAKLDKDIAQKTEKKMVQL------QSASGMSWIE
VQYLNSASQALQTCRQTLKWTYAFAFYLARNNLTEIFEDNQKDLEMAVENLSEMFEKPIT
ELSDPK----------------------------------------LKVDIMDKTSYCN-
--KRRVILLEDTAENLANG----------E-----------WNFNADLLAATTSAPVHRR
--------------------------------------------
>gi|156546859|ref|XP_001606523.	Nasonia vitripennis
------------------------------------------------------------
------------------------------------------------------------
----------------MDSEDDSCYDDID-------------------------------
-------------------------------SGNESSGD---------------------
--ELESTVNP-QEKAMDV------------------------------------------
------DEYKFEV-L--------------------------------------STEQIVQ
HMADTI---------------------KEVNTVVEIPATTTRILLNHFSWDKE-------
--------KLM-------------------------------------------------
---------------------------------ERFYDGDQEKLFEEAR-----------
----------------------VVNPFRK---------GSAINRSLPNSLSLKCNLANET
EECGVCYLTLPS-HMMSGLECGHRFCTDCWREYLHTKIMKEGVGQTIPCAAHD--CDILV
DDASVMRL--VEDSAVKLKYQHLITNNFVECNRLLKWCRSPNCNNAIKVLYVETK-----
-PVTCK-CNHTF-------CF--NCGENW-----------HDPVQCDILRKW--------
--------------------------------------IKKC-----NDDSETSNW--IM
ANTKEC-----------------RKCKAIIEKNGGCNH----MICKNKSCR------AEF
CWICLGP-WKTHSTSSY-CNRYEEEDGKEAKTAREKSHKALQKYLFYS------------
-----------NRYA------NHLQSLNLENNLYKSVKTKMQEM------QERN-VSWIE
VQFLKTAVDVLCSCRQTLMYSYVFAFYVKKNNQSAIFEDNQQDLESATEILSGYLERDIA
GEDLVD----------------------------------------IKQKVQDKYRYCN-
--SRRKVLVEHVQEGRDKD----------W-----------WEIEQETTQRAVCISFGDL
FY------------------------------------------
>gi|70992567|ref|XP_751132.1|	Aspergillus fumigatus
------------------------------------------------------------
------------------------------------------------------------
----------------MDSDDDFMTDASSADDFLDT------------------------
-------------------------------QGSEDESLGE-------------------
--EFGDEFDG-GFSQDKD----------------------------------------LL
GNTKKPYEVDFRV-L--------------------------------------SPEDIDR
EQSQQV---------------------NEVSQILGLPPESSAILLRFGRWNRE-------
--------KLI-------------------------------------------------
---------------------------------ESYMDHPEETLEEAGLGT---------
----------------------NFDMTPK-------------------------TEVVPG
FMCDICCEDGDD-LETYAMRCGHRFCVDCYRHYLAQKIREEGEAARIECPGDG--CHMIV
DSKSL-SL--LVADDLKERYQTLLMRTYVDDKENLKWCPAPNCEYAVDCPVKQRDLNRIV
PTVQCA-CKHFF-------CF--GCTLND-----------HLPSPCKLVKMW--------
--------------------------------------LKKC-----EDDSETANW--IS
ANTKEC-----------------PKCHSTIEKNGGCNH----MTCRK--CK------HEF
CWMCMGL-WSEHGTSWYNCNRYEEKSGSEARSAQAKSRASLERYLHYY------------
-----------NRYA------NHEQSAKLDKDLYLKTEKKMTSL------QSQSGLSWIE
VQFLDTASQALQQCRQTLKWTYAFAYYLARNNLTEIFEDNQKDLELAVESLSEMFEKPVP
E--LAN----------------------------------------LKVDILDKTAYCN-
--KRRVILLSDTAQKLKQGKLYSLHNVDAWHKADNHISSGVWSFNVEW------------
--------------------------------------------
>gi|157116029|ref|XP_001658347.	Aedes aegypti
------------------------------------------------------------
------------------------------------------------------------
----------------MSTDFPQS------------------------------------
-------------------------------VREKWYHCSLE------------------
--DCDIEQI--DPKRSDP------------------------------------------
------ECFVYEC-L--------------------------------------NVEEVEK
LLNESV---------------------ERLSNQLHITPSLAKVLLHETKWNTA-------
--------EVV-------------------------------------------------
---------------------------------EKYRNNASNLLVSARIKAAPSVMASSS
SATIVPLLVPSSSSNSSAVLLPVCSMIPA--------TGPIPGTSAKPTIQTMSSSAYRT
HLCPVCVTVQSM-DKFHSLSCQHSFCRDCWAMHFEIQI-SQGISTQIGCMEQR--CDVRV
PEDLVLNL--LNRPMLRDKYQQFAFADYVKSHPELRFCPGPNCQIIIRSADISPK-----
-KAICKICMTSF-------CF--RCGTDY-----------HAPTDCQIIRKW--------
--------------------------------------LTKC-----ADDSETANY--IS
AHTKDC-----------------PKCHICIEKNGGCNH----MQCFN--CK------HDF
CWMCLGD-WKAHGSEYYECSRYKENPNIAHESVHAQAREALKKYLHYY------------
-----------ERWE------NHSKSLQLEEQTLDRMKTRINEK------VMKGLGTWID
WQYLFDAAALLAKCRYTLQYTYPYAYFMEAGSRKDLFEYQQAQLEAEIENLSWKVERAET
TD---------------------------------------------RGDLENQMDVAE-
--KRRTTLLKDFFPTEA-------------------------------------------
--------------------------------------------
>gi|56118682|ref|NP_001008118.1	Xenopus tropicalis
------------------------------------------------------------
------------------------------------------------------------
----------------MSREDKEAQEDELLALASIYSEDEFK------------------
-------------------------------RLETAPGGEICVCLDLPPNFSVAIKG---
--DCASNEYM-GSFESIV-----------------------------SFLPPIILDFELP
PGYPSTDPPAFKL-S--------------------------------------CKWLSPS
QLALLC---------------------QRLDDLWVEYAGEVVLFAWMQFLKEGTLEYLKI
NSPYE--IQLC-------------------------------------------------
---------------------------------EFGPKCIKNNLGISDS-----------
-------CSATGPAEAVIWDTRAIQDVES-------VTTLIDCILDFNEAQQKKCFDSKS
YMCDICFSEKVGSECTHFKKCEHIYCNACLKDYYTVQI-QDGQVQALNCPEPK--CSSVA
TPAQV-KL--LVGEELFSRYDRLLLQSSLDLMADVVYCPRPNCRTPV-MLEPGGE-----
-MGICSSCKYAF-------CT--LCKLAY-----------HAVAYCNITSEKLLL-----
--------------VRDEYLEADAAGKKLLERRYGKNVIVKA------VEMRSFEW--LE
KNSKRC-----------------PSCRANVEKIDGCNR----MFCTR--CN------KNF
CWLCLAV-LSNGDPYDHF------------------------------------------
---------------------NSSSSG---------------------------------
------------------------CFNL-------LFEPQKA------------------
------------------------------------------------------------
------------------------------------------------------------
--------------------------------------------
>gi|6453815|ref|NP_005735.1|	Homo sapiens
------------------------------------------------------------
------------------------------------------------------------
----------------MDSDEGYNYEFDEDEECSEEDSGAEE------------------
-------------------------------EEDEDDDEPDDDTLDLGEVELVEPGL---
--GVGGERD--GLLCGET------------------GGGGGSALGPGGGGGGGGGGGGGG
PGHEQEEDYRYEV-L--------------------------------------TAEQILQ
HMVECI---------------------REVNEVIQNPATITRILLSHFNWDKE-------
--------KLM-------------------------------------------------
---------------------------------ERYFDGNLEKLFAECH-----------
----------------------VINPSKK-----------------SRTRQMNTRSSAQD
MPCQICYLNYPN-SYFTGLECGHKFCMQCWSEYLTTKIMEEGMGHTISCPAHG--CDILV
DDNTVMRL--ITDSKVKLKYQHLITNSFVECNRLLKWCPAPDCHHVVKVQYPDAK-----
-PVRCK-CGRQF-------CF--NCGENW-----------HDPVKCKWLKKW--------
--------------------------------------IKKC-----DDDSETSNW--IA
ANTKEC-----------------PKCHVTIEKDGGCNH----MVCRNQNCK------AEF
CWVCLGP-WEPHGSAWYNCNRYNEDDAKAARDAQERSRAALQRYLFYC------------
-----------NRYM------NHMQSLRFEHKLYAQVKQKMEEM------QQHN-MSWIE
VQFLKKAVDVLCQCRATLMYTYVFAFYLKKNNQSIIFENNQADLENATEVLSGYLERDIS
QDSLQD----------------------------------------IKQKVQDKYRYCE-
--SRRRVLLQHVHEGYEKD----------L-----------WEYIED-------------
--------------------------------------------
>gi|109477287|ref|XP_001060328.	Rattus norvegicus
------------------------------------------------------------
------------------------------------------------------------
----------------M-------------------------------------------
------------------------------------------------------------
--ECASTADG-CETRLHP------------------------------------------
-----------QA----------------------------------------RPYAVIA
YGCASC---------------------PKLTCEREGC-QTEFCYHCKQIWHPN-------
--------QTC-------------------------------------------------
---------------------------------DMARQQRAQTLRVRTKHT---------
----SGLSYGQESGPED-----DTRTHYR--------CSLVRRV----SCLHI----CSC
YLIVMCQTERKELQFWSPSGCTF-WGKKPWSR--KKKILWQ-LGTLIGAPVGISLIAGIA
IPAMVIGIPVYVGRKIHSRYEGRKTSKHKRNLAITGGVTLSVIASPVIAAVSVGI-----
-GVPIM-LAYVYGVVPISLCRGGGCGVSTANGKGVKIEFDEDDGPITVADAWRAL-----
----------------KNPSIGESSIEGLTSVLSTSGSPTDGLSVMQGPYSETASFAALS
GGTLSGGILSSG-----------KGKYSRLEVQADVQK----EIFPKDTASLGAISDSAS
TRAMAGSIISSYNPQDRECNNMEIQVDIEAKPSHYQLVSGS-------------------
---------------------STEDSLHVHAQVAENEEEGNGGG------AGGGSGGSED
DPPYKHQSCEQKDCLASKAWDISLA---QPESIRSDLESSDTQSDDVPDITSDECGSPRP
HTAACP----------------------------------------STPRVHGAPSPSA-
--HKSLAAPAEGQTVLKPE-----------------------EYEVE-------------
--------------------------------------------
>gi|24662189|ref|NP_648392.1|	Drosophila melanogaster
------------------------------------------------------------
------------------------------------------------------------
----------------MNSEME--------------------------------------
-------------------------------FSDEDHGDSHRSLLTHM------------
--SCENDSDS-EDTCTEI-------------------------------------LLPEN
SNSPETEDFVYKV-L--------------------------------------SVDQIVQ
HQRNII---------------------DEVNNVLNLPPQVTRIILNHFKWDKE-------
--------SLF-------------------------------------------------
---------------------------------ENYFESNPKDFFQRAH-----------
----------------------VLNPFEK--------------KIERESAASTSCAI--P
QLCGICFCSCDE---LIGLGCGHNFCAACWKQYLANKTCSEGLANTIKCPAAN--CEILV
DYISFLKL--ADDSEVVERYQQLITNTFVECNMLMRWCPAPNCSHAVKAVCAEPR-----
-AVLCK-CGHEF-------CF--ACGENW-----------HEPASCSSLKKW--------
--------------------------------------VKKC-----LEDSETSNW--IA
QNTKEC-----------------PKCNVTIEKDGGCNH----MVCKNPSCR------YDF
CWVCLGS-WEPHGSSWYSCNRFDEEEAKQARLAQQKYRSSMARYLHYY------------
-----------NRYS------NHMQSLKMENKLYSNIQAKMDDM------QEE--MSWIE
VQFLRDAVDVLCQCRTTLMYSYVFAFYLMNNNQKIIFEDNQKDMEMATEKLSECLEREIT
VKNIYE----------------------------------------VKQKVLDLSHYCQ-
--KRRHVLLCHVREGYEND----------W-----------WEFKEETTT----------
--------------------------------------------
>gi|157015877|gb|EAA11275.4|	Anopheles gambiae
------------------------------------------------------------
------------------------------------------------------------
---------------MADQESDMEYSSDNDY-----------------------------
-------------------------------EFEDYYNSGE-------------------
--DCDIEQI--DPKRTDP------------------------------------------
------EYFVYEC-L--------------------------------------NVEEVEK
LLNESV---------------------EKLSTQLQITPSLAKVLLHETRWNTA-------
--------EVI-------------------------------------------------
---------------------------------ERYRNNASNLLVSARIKA---------
----------------------AAPPSVP------AATSPAPQQSSPVPSTSSAAAVATA
ALCPVCVTVQST-DKFHALACQHSFCRDCWAMHFEIQI-GQGISTQIECMEQR--CDVRV
PEDLVLTL--LNRPMLRDKYQQFTFADYVKSHPELRFCPGPNCQTIIRSQDISPK-----
-KAVCRMCKTAF-------CF--RCGTDY-----------HAPTDCQIIRKW--------
--------------------------------------LTKC-----ADDSETANY--IS
AHTKDC-----------------PKCHICIEKNGGCNH----MQCFN--CK------HDF
CWMCLGD-WKAHGSEYYECSRYKENPNIAHESVHAQAREALKKYLHYY------------
-----------ERWE------NHSKSLQLEQQTLDRMRARINEK------VMKGLGTWID
WQHLFDAATLLAKCRYTLQYTYPYAYYME--SRKELFEYQQAQLEAEIENLSWKVERAET
TD---------------------------------------------RGELENQMDIAE-
--KRRTTLLKDFFPTEA-------------------------------------------
--------------------------------------------
>gi|109001743|ref|XP_001099161.	Macaca mulatta
------------------------------------------------------------
------------------------------------------------------------
----------------MGSEKDSESPRSTSLHAAAPDPKCRNS-----------------
---------------GRRRRLTFHS------LAPRLLSCPHRSCRDCLRHYLRLEIS---
--ESRVPIS--CPECSER-----------------LNPHDIRLLLADPPLMHKYEEFMLR
RYLASDPDCRWCPAPD-------------------------------------CGYAVIA
YGCASC---------------------PKLTCEREGC-QTEFCYHCKQIWHPN-------
--------QTC-------------------------------------------------
---------------------------------DMARQQRAQSLRVRTKHT---------
----SGLSYGQESGPD------DIKPCPR--------CSAYIIKMNDGSCNHMTCAVCGC
EFCWLCMKEISDLHYLSPSGCTF-WGKKPWSR--KKKILWQ-LGTLIGAPVGISLIAGIA
IPAMVIGIPVYVGRKIHSRYEGRKTSKHKRNLAITGGVTLSVIASPVIAAVSVGI-----
-GVPIM-LAYVYGVVPISLCRGGGCGVSTANGKGVKIEFDEDDGPITVADAWRAL-----
----------------KNPSIGESSIEGLTSVLSTSGSPTDGLSVMQGPYSETASFAALS
GGTLSGGILSSG-----------KGKYSRLEVQADVQK----EIFPKDTASLGAISDNAS
TRAMAGSIISSYNPQDSSTPR---------------------------------------
------------------------------------------------------------
------------------------------------------------------------
--------------------------------------------------AQGAPSPSA-
--HMNLSALAEGQTVLKPE-----------------------GGEARV------------
--------------------------------------------
>gi|120577506|gb|AAI30178.1|	Xenopus laevis
------------------------------------------------------------
---------SWFGIFCLSEMTEGSAEPPPCPGARRRRLLLSLPNVFPGRTRAAPEPSVPS
PPPSPPPPPPPVSVPPPPSSPGGSESLIECPLCLVRQPPE--------------------
-------------------------------EIPELLSCRHRSCLRCLRQYLRIEIC---
--ESRVNLR--CPECAER-----------------LSPQHVRAILRDPLLTRKYEEFLLR
RCLAADPDCRWCPAPD-------------------------------------CGYAVIA
YGCASC---------------------PKLTCEREGC-RTEFCYHCKHVWHPN-------
--------QTC-------------------------------------------------
---------------------------------DMARQQRAPSLGVRRKHP---------
----SGISYGQESGSAD-----DMKSCPR--------CSAYIIKMNDGSCNHMTCSVCGC
EFCWLCMKEISDLHYLSPSGCTF-WGKKPWSR--KKKIIWQ-LSTLIGAPVGISLIAGIA
IPAMVIGIPVYVGRKIHGRFENKKTSRHKKNLAVTGGVILSVIASPVVAAVSVGI-----
-GVPIM-LAYVYGVVPVSLCRGGGCGVTTANGKGVKIDF-EEDGPITVADAWRAL-----
----------------KNPSIGESSMEGLTSVLSTSGSPTDGLSVLQGNYSETASFAALA
GGTLTGGMLSGG-----------RAKYCRLEVQADVQK----ETCQKDSVSLGAVSDSAS
TRAMAGSIISSYNPQEREVNNMEIQVHIEAKPSRYQLMSES-------------------
---------------------STEESLHASAPLVESEDAEACRN----------------
---------QVAACDITLA---------QPESIRSDLESSDAQSDDVPDLASEEYDSPHL
FPPSPS----------------------------------------NALQESPPHRMCA-
--QEEG--LCAHEESLSKV-----------------------EIIELRV-----------
--------------------------------------------
>gi|125979477|ref|XP_001353771.	Drosophila pseudoobscura
------------------------------------------------------------
------------------------------------------------------------
----------------MNADP---------------------------------------
-----------------------SD------YSDEDHGDAD---RSMHSCNSSPSSY---
--SMHTDSD--EDTCTEI----------------------------------LLPEREAK
PSGADQDDFKYEV-L--------------------------------------SVTQIVQ
HQWQII---------------------DEVNSVLSLPPQITRCILNQYKWNKE-------
--------RLF-------------------------------------------------
---------------------------------EEYFDSSPEEFFQRAH-----------
----------------------LVNPFIK--------------APAHVSFEGNGVGGQEE
DICGICLC--PS-DDLRSLGCGHKFCSDCWKQYLAQKTFGEGLGHSIACPAEN--CEIVV
DYVSFLIL--ADDREVIGRYQQLITNTFVECNALLRWCPAPSCCRAIQVNNPEAR-----
-AVRCK-CGHQF-------CF--GCGENW-----------HEPASCSLLRQW--------
--------------------------------------LKKC-----REDSETSNW--IA
QNTKEC-----------------PKCNVTIEKDGGCNH----MVCKNPNCR------YDF
CWVCLGS-WEPHGSSWYSCNRFNEEEAKKARLAQQQYRSTMARYLHYY------------
-----------NRYM------NHMQSRRLEHNIYAKVQAKMKAM------RET--MTWFE
VQFLEEAVEVLCQCRVTLMYSYVFAYYLRNNNQKIIFEDNQRDLESATEKISECLEREIT
APNLQS----------------------------------------IRLKVLDLSHYCE-
--RRRSVLLCHVREGNEKD----------W-----------WEFTDD-------------
--------------------------------------------
>gi|126272244|ref|XP_001365122.	Monodelphis domestica
------------------------------------------------------------
------------------------------------------------------------
----------------MDSDEGYNYEFDEDEECSEEDSGAEE------------------
-------------------------------EEDDDDEEPDDDNLDLGEVELVEPGL---
--GVGGERD--GLLCGET-------------------GGGGGGSALGPGGGGGGGGGGGG
PGHEQEEDYRYEV-L--------------------------------------TAEQILQ
HMVECI---------------------REVNEVIQNPATITRILLSHFNWDKE-------
--------KLM-------------------------------------------------
---------------------------------ERYFDGNLEKLFAECH-----------
----------------------VINPSKK-----------------SRTRQMNTRSSAQD
MPCQICYLNYPN-SYFTGLECGHKFCMQCWSEYLTTKIMEEGMGQTISCPAHG--CDILV
DDSTVMRL--ITDSKVKLKYQHLITNSFVECNRLLKWCPAPDCHHVVKVQYPDAK-----
-PVRCK-CGRQF-------CF--NCGENW-----------HDPVKCKWLKKW--------
--------------------------------------IKKC-----DDDSETSNW--IA
ANTKEC-----------------PKCHVTIEKDGGCNH----MVCRNQNCK------AEF
CWVCLGP-WEPHGSAWYNCNRYNEDDAKAARDAQERSRAALQRYLFYC------------
-----------NRYM------NHMQSLRFEHKLYAQVKQKMEEM------QQHN-MSWIE
VQFLKKAVDVLCQCRATLMYTYVFAFYLKKNNQSIIFENNQADLENATEVLSGYLERDIS
QDSLQD----------------------------------------IKQKVQDKYRYCE-
--SRRRVLLQHVHEGYEKD----------L-----------WEYIED-------------
--------------------------------------------
>gi|114657983|ref|XP_510520.2|	Pan troglodytes
------------------------------------------------------------
------------------------------------------------------------
----------------MDSDEGYNYEFDEDEECSEEDSGAEE------------------
-------------------------------EEDEDDDEPDDDTLDLGEVELVEPGL---
--GVGGERD--GLLCGET------------------GGGGGSALGPGGGGGGGGGGGGGG
PGHEQEEDYRYEV-L--------------------------------------TAEQILQ
HMVECI---------------------REVNEVIQNPATITRILLSHFNWDKE-------
--------KLM-------------------------------------------------
---------------------------------ERYFDGNLEKLFAECH-----------
----------------------VINPSKK-----------------SRTRQMNTRSSAQD
MPCQICYLNYPN-SYFTGLECGHKFCMQCWSEYLTTKIMEEGMGQTISCPAHG--CDILV
DDNTVMRL--ITDSKVKLKYQHLITNSFVECNRLLKWCPAPDCHHVVKVQYPDAK-----
-PVRCK-CGRQF-------CF--NCGENW-----------HDPVKCKWLKKW--------
--------------------------------------IKKC-----DDDSETSNW--IA
ANTKEC-----------------PKCHVTIEKDGGCNH----MVCRNQNCK------AEF
CWVCLGP-WEPHGSAWYNCNRYNEDDAKAARDAQERSRAALQRYLFYC------------
-----------NRYM------NHMQSLRFEHKLYAQVKQKMEEM------QQHN-MSWIE
VQFLKKAVDVLCQCRATLMYTYVFAFYLKKNNQSIIFENNQADLENATEVLSGYLERDIS
QDSLQD----------------------------------------IKQKVQDKYRYCE-
--SRRRVLLQHVHEGYEKD----------L-----------WEYIED-------------
--------------------------------------------
>gi|93003266|tpd|FAA00216.1|	Ciona intestinalis
------------------------------------------------------------
------------------------------------------------------------
-------------MNKEDRENELLALESILDPCSF-------------------------
-------------------------------AFNETTGRID-----------VFPQLQTN
YIKLTSEVKS-EKSCDDS----------------------HNKEHFVSFLPPIQLNFALS
DGYPSDEPPQFNL-S--------------------------------------CVWLSPS
QLYELC---------------------LKLDEIWQKEEGNVILYEWFQFLQDDSLSILGI
NDNL----HIC-------------------------------------------------
---------------------------------DEFESSSQSSTIASSKPG---------
----------------------INKPCKRGLQTAHSYAEILPTLLNYDQQKQQEIFFTSV
FSCNICFVDKKGTDCLQFKDCGHVYCKQCITSYFEIHI-SEGTITSLICPEPD--CDTTA
LPNQV-KE--AVNKDLYERYEKLLLQTTLDTMTDIVFCPLMHCQSAV-IIEPEAS-----
-IGQCPSCAYAF-------CV--HCKLAY-----------HGVSPCKIASHEIIK-----
--------------LCKEYESANEEKKKQMEKKYGRKVLCKA-----LDDRATQAW--MN
NNTKPC-----------------PGCNASIEKLDGCNK----MTCYK--CR------AYF
CWICMHV-LDCANPYRH-------------------------------------------
---------------------YNNIGSPCNNRLFEGIDPEDQEF----------------
-----------------------FMYY---------------------------------
------------------------------------------------------------
------------------------------------------------------------
--------------------------------------------
>gi|73974104|ref|XP_856219.1|	Canis familiaris
------------------------------------------------------------
------------------------------------------------------------
----------------MGSDRDLQSSASSVSLPSVKKA----------------------
-------------------------------PKKRRISIGSLSCVDCLRQYLRIEIS---
--ESRVNIS--CPECTER-----------------FNPHDIRLILSDDVLMEKYEEFMLR
RWLVADPDCRWCPAPD-------------------------------------CGYAVIA
FGCASC---------------------PKLTCGREGC-GTEFCYHCKQIWHPN-------
--------QTS-------------------------------------------------
---------------------------------D--------------------------
----------------------DIKPCPR--------CAAYIIKMNDGSCNHMTCAVCGC
EFCWLCMKEISDLHYLSPSGCTF-WGKKPWSR--KKKILWQ-LGTLVGAPVGIALIAGIA
IPAMIIGIPVYVGRKIHNRYEGKDVSKHKRNLAI------------------TGI-----
-GVPIM-LAYVYGVVPISLCRSGGCGVSAGNGKGVRIEF-DDENDINVGGTNTAV-----
-----------------------------------------------DNLSETASTMALA
GASITGSLSGSAM----------VNCFNRLEVQADVQKERYSLSGESGTVSLGTVSDNAS
TKAMAGSILNSYIPLDKEGNSMEVQVDIESKPSKFRHNSGSSSVEDGS--ATR-SHPGGS
SSGFPEGKVGATKWSKEATAGKKAKSGKLRKKSNMKINETREDMDAQLLEQQSTNSSEFE
APSLSDSMPSVADSHSSHFSEFS-CSDLESMKTSCSHGSNDYHARFATVNILPEVENDRL
ENSPHQ----------------------------------------CSISVLTKTASCSE
VPQLNHIAEEHGNNGIKPN-------VDLYFGDVLKETNNNHSHQTMELKVAIQTEI---
--------------------------------------------
>gi|67968421|dbj|BAE00572.1|	Macaca fascicularis
------------------------------------------------------------
------------------------------------------------------------
----------------MHKYEEF-------------------------------------
------------------------------------------------------------
---------------------------------------------------------MLR
RYLASDPDCRWCPAPD-------------------------------------CGYAVIA
YGCASC---------------------PKLTCEREGC-QTEFCYHCKQIWHPN-------
--------QTC-------------------------------------------------
---------------------------------DMARQQRAQSLRVRTKHT---------
----SGLSYGQESGPD------DIKPCPR--------CSAYIIKMNDGSCNHMTCAVCGC
EFCWLCMKEISDLHYLSPSGCTF-WGKKPWSR--KKKILWQ-LGTLIGAPVGISLIAGIA
IPAMVIGIPVYVGRKIHSRYEGRKTSKHKRNLAITGGVTLSVIASPVIAAVSVGI-----
-GVPIM-LAYVYGVVPISLCRGGGCGVSTANGKGVKIEFDEDDGPITVADAWRAL-----
----------------KNPSIGESSIEGLTSVLSTSGSPTDGLSVMQGPYSETASFAALS
GGTLSGGILSSG-----------KGKYSRLEVQADVQK----EIFPKDTASLGAISDNAS
TRAMAGSIISSYNPQDRECNNMEIQVDIEAKPSHYQLVSGS-------------------
---------------------STEDSLHVHAQMAENEE------------EGSGGGGSEE
DPPCRHQSCEQKDCLASKPWDISLA---QPESIRSDLESSDTQSDDVPDITSDECGSPRS
HTAACP----------------------------------------STPRAQGAPSPSA-
--HMNLSALAEGQTVLKPE-----------------------GGEARV------------
--------------------------------------------
>gi|148698273|gb|EDL30220.1|	Mus musculus
------------------------------------------------------------
--------LLSLGGLPRRWRRRRRPGRRLGGGAEAGATAALGAPGSSASAGHGVEALPSE
PAAEAEAEAVAAGPEEDEAAEGGGAEEVECPLCLVRLPPE--------------------
-------------------------------RAPRLLSCPHRSCRDCLRHYLRLEIS---
--ESRVPIS--CPECSER-----------------LNPHDIRLLLADPPLMHKYEEFMLR
RYLASDPDCRWCPAPD-------------------------------------CGYAVIA
YGCASC---------------------PKLTCEREGC-QTEFCYHCKQIWHPN-------
--------QTC-------------------------------------------------
---------------------------------DMARQQRAQTLRVRTKHT---------
----SGLSYGQESGPAD-----DIKPCPR--------CSAYIIKMNDGSCNHMTCAVCGC
EFCWLCMKEISDLHYLSPSGCTF-WGKKPWSR--KKKILWQ-LGTLIGAPVGISLIAGIA
IPAMVIGIPVYVGRKIHSRYEGRKTSKHKRNLAITGGVTLSVIASPVIAAVSVGI-----
-GVPIM-LAYVYGVVPISLCRGGGCGVSTANGKGVKIEFDEDDGPITVADAWRAL-----
----------------KNPSIGESSIEGLTSVLSTSGSPTDGLSVMQGPYSETASFAALS
GGTLSGGILSSG-----------KGKYSRLEVQADVQK----EIFPKDTASLGAISDSAS
TRAMAGSIISSYNPQDRECNNMEIQVDIEAKPSHYQLV----------------------
------------------------------------------------------------
--YLLPYAVKDGASRQQPLWKILLLRLHRPPCISLHIGTGNA--VNGLGVSVRKCPRDVP
VRLKEP----------------------------------------VGGKRQTVWRPLK-
--CKQPTRDLQFF-----------------------------------------------
--------------------------------------------
>gi|47086193|ref|NP_998088.1|	Danio rerio
------------------------------------------------------------
------------------------------------------------------------
----------------MDSDEGYNYEFDDEEEEEEEEEECS-------------------
-----------------------VD------SGEEEAVDDS---LELGEVELL-------
--DPAVAGGE-PDDCADT-------------------------------------GGGGP
GPGQEDEDYRFEV-L--------------------------------------TTEQILQ
HMVECI---------------------RDVNEVIQNPATITRILLSHFNWDKE-------
--------KLM-------------------------------------------------
---------------------------------ERYFDGNLDKLFSECH-----------
----------------------VINPSKK-----------------PKTRPMSTRSSSQD
LPCQICYLNYPN-SYFTGLECGHKFCMQCWGDYLTTKIIEEGMGQTISCPAHN--CDILV
DDNTVMRL--ITDSKVKLKYQHLITNSFVECNRLLKWCPAPDCHHVVKVQYPDAK-----
-PVRCK-CGRQF-------CF--NCGENW-----------HDPVKCKWLRKW--------
--------------------------------------IKKC-----DDDSETSNW--IA
ANTKEC-----------------PKCHVTIEKDGGCNH----MVCRNQNCK------AEF
CWVCLGP-WEPHGSAWYNCNRYNEDDAKAARDAQERSRAALQRYLFYC------------
-----------NRYM------NHMQSLRFEHKLYAQVKQKMEEM------QQHN-MSWIE
VQFLKKAVDVLCQCRSTLMFTYVFAFYLKKNNQSIIFENNQADLENATEVLSGYLERDIS
QDSLQD----------------------------------------IKQKVQDKYRYCE-
--SRRRVLLQHVHEGYEKD----------L-----------WEYIED-------------
--------------------------------------------
>gi|149694708|ref|XP_001499804.	Equus caballus
------------------------------------------------------------
------------------------------------------------------------
------------MAVLQEAQQEAGAVFQEGQGCCSRTRGSGGG-----------------
---------------NGWEDGKGGIPE----AASPTVGKLDLDGKHCGCNSLASPLLPRA
AADCGGIPGP-SPERPQR--------------SCGMRRAGAGWRGGRMAGMPVFPGRLGR
GGKG--KLVTWRCPIGGSKQPGLLGFPGTEQAPPLVRALGRGGRGVGALTQRRAGYAVIA
YGCASC---------------------PKLTCEREGC-QTEFCYHCKQIWHPN-------
--------QTC-------------------------------------------------
---------------------------------DMARQQRAQTLRVRTKHT---------
----SGLSYGQESGPAD-----DIKPCPR--------CSAYIIKMNDGSCNHMTCAVCGC
EFCWLCMKEISDLHYLSPSGCTF-WGKKPWSR--KKKILWQ-LGTLIGAPVGISLIAGIA
VPAMVIGIPVYVGRKIHSRYEGRKTSKHKRNLAITGGVTLSVIASPVIAAVSVGI-----
-GVPIM-LAYVYGVVPISLCRGGGCGVSTANGKGVKIEFDEDDGPITVADAWRAL-----
----------------KNPSIGESSIEGLTSVLSTSGSPTDGLSVMQGPYSETASFAALS
GGTLSGGILSSG-----------KGKYSRLEVQADVQK----EIFPKDTASLGAISDNAS
TRAMAGSIISSYNPQDRECNNMEIQVDIEAKPSHYQLVSGS-------------------
---------------------STEDSLHVHAQMAENE----EGS------GGGGGGSNEE
DPPCKHQSCEQKDCLASKPWDISLA---QPESIRSDLESSDTQSDDVPDITSDECGSPRS
HTAACP----------------------------------------STPRAQGAPSPSA-
--HMNLSAPAEGKTVLKPE-----------------------GAEAR-------V-----
--------------------------------------------
>gi|76155465|gb|AAX26755.2|	Schistosoma japonicum
------------------------------------------------------------
------------------------------------------------------------
--FYSCDLLHDSRSQVKKCNELTSFSENEIECPVCLMPTE--------------------
-------------------------------DPLQLNSCGHFACSVCWRNFISSQIE---
--NFALAHLT-CVACSELLQPSTIIHLLSAVADRHESLHSPVKENQYARSLARYEEFLLQ
QVMSREPEARWCPRG--------------------------------------CGYGLIA
HSFQAC---------------------PQIVCLHPECEGRSFCFKCKRPWSTDIKNGSSS
HQNNV--VHICPVEQDIRSNTLDGLRAFFGIRRFSRQISGQNSKAHGPQQKVPDTVLPIH
LSTSTPKKEKRPRVSKSFPTSGDYASDTRLSMEELFPDADLENANNAAHALEKKRPVSNT
DMANSSESAPKTNKRRSVDSDGQVKPCPN--------CKTLIQKLNDGSCNSMVCSICNY
EFCWLCLREITATHYLNFSGCTV-LGRSRWS---KLRRFVAVCGIILGTPIILPLTIVIA
LPALSIGFTVSITKPINRVF--LSKSKHLRRFVVFWVVIAGLILFPILTALTFGV-----
-LIPIV-LGYVY-------LY----------------------LPISLLRSL--------
--------------------------------------IRDE----SEVLSESTELEKLQ
SVTQTF-----------------------VDEFEAKND----VKLNDGN--------LNE
SKIII---V---------------------------------------------------
------------------------------------------------------------
-------------------------------NETISIESDQTP-----------------
------------------------------------------------------------
------------------------------------------------------------
--------------------------------------------
>gi|149442717|ref|XP_001520758.	Ornithorhynchus anatinus
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
---------------------------------D--------------------------
----------------------DIKPCPR--------CAAYIIKMNDGSCNHMTCAVCGC
EFCWLCMKEISDLHYLSPSGCTF-WGKKPWSR--KKKILWQ-LGTLVGAPVGIALIAGIA
IPAMIIGIPVYVGRKIHNRYEGKDISKHKRNLAIAGGVTLSVIVSPVVAAVTVGI-----
-GVPIM-LAYVYGVVPISLCRSGGCGVSAGNGKGVRIEF-DDENDINVGGTNTAVDTTS-
-----------VAEARHNPSIGEGSVGGLTGSLSASGSHMDRIGAIRDNLSETASTMALA
GASITGSLSGSAM----------VNCFNRLEVQADVQKERYSLSGESGTVSLGTVSDNAS
TKAMAGSILNSYIPLDKEGNSMEVQVDIESKPAKFRHHSGSSSVDDGSVPSRG-NAAAGP
GGGLPDGKSSAPKWSKEAAA-GKKSKGKLRKKSSMKINETREDMDAQLLEQQSTNSSEFD
SPSLSDSLPSVAESHSSHFSEFS-CSDLESMKTSCSHGSSDYHARFATVSVLPEVENDRL
ENSPVPSGGDGPAPSHGAEERSDPGGTRAVGSCFRDVLKEAKKNHHAQPAFHSLTSPCP-
--RWTKILSLHFSRSEVSGAREKATQTLPYVETVVRELETARLTTRDRFDACASVSEETV
DASL----------------------------------------
>gi|119906716|ref|XP_592217.3|	Bos taurus
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-------------------------------------------------------YAVIA
FGCASC---------------------PKLTCGREGC-GTEFCYHCKQIWHPN-------
--------QTC-------------------------------------------------
---------------------------------DAARQERAQSLRLRTIRS---------
----SSISYSQESGAAAD----DIKPCPR--------CAAYIIKMNDGSCNHMTCAVCGC
EFCWLCMKEISDLHYLSPSGCTF-WGKKPWSR--KKKILWQ-LGTLVGAPVGIALIAGIA
IPAMIIGIPVYVGRKIHNRYEGKDVSKHKRNLAIAGGVTLSVIVSPVVAAVTVGI-----
-GVPIM-LAYVYGVVPISLCRSGGCGVSAGNGKGVRIEF-DDENDINVGGTNTAVDTTS-
-----------VAEARHNPSIGEGSVGGLTGSLSASGSHMDRIGAIRDNLSETASTMALA
GASITGSLSGSAM----------VNCFNRLEVQADVQKERYSLSGESGTVSLGTVSDNAS
TKAMAGSILNSYIPLDKEGNSMEVQVDIESKPSKFRHNSGSSSVEDGSATR---SHPGGS
SGGLPEGKSSATKWSKEATAGKKSKSGKLRKKSNMKINETREDMDAQLLEQQSTNSSEFE
APSLSDSMPSVADSHSSHFSEFS-CSDLESMKTSCSHGSTDYHARFATVNILPEVENDRL
ENSPHQ----------------------------------------CSISVLTQTASCS-
--EVPQ--LNHIAEEHGNSGIKPSVDL--YFGSALKETNNNHSHQTMELKVAIQTDI---
--------------------------------------------
>gi|108874405|gb|EAT38630.1|	Aedes aegypti
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-------------------------------YLSYSAGLE--------------------
--DCDIEQI--DPKRSDP------------------------------------------
------EYFVYEC-L--------------------------------------NVEEVEK
LLNESV---------------------ERLSNQLHITPSLAKVLLHETKWNTA-------
--------EVV-------------------------------------------------
---------------------------------EKYRNNASNLLVSARIKAAPSVMASTS
SATVVP----------------LLVPSTT---------GPIPGTSAKPTIQTMSSSAYRT
HLCPVCVTVQSM-DKFHSLSCQHSFCRDCWAMHFEIQI-SQGISTQIGCMEQR--CDVRV
PEDLVLNL--LNRPMLRDKYQQFAFADYVKSHPELRFCPGPNCQIIIRSADISPK-----
-KAICKICMTSF-------CF--RCGTDY-----------HAPTDCQIIRKW--------
--------------------------------------LTKC-----ADDSETANY--IS
AHTKDC-----------------PKCHICIEKNGGCNH----MQCFN--CK------HDF
CWMCLGD-WKAHGSEYYECSRYKENPNIAHESVHAQAREALKKYLHYY------------
-----------ERWE------NHSKSLQLEEQTLDRMKTRINEK------VMKGLGTWID
WQYLFDAAALLAKCRYTLQYTYPYAYFMEAGSRKDLFEYQQAQLEAEIENLSWKVERAET
TD---------------------------------------------RGDLENQMDVAE-
--KRRTTLLKDFFPTEA-------------------------------------------
--------------------------------------------
