>gi|126307932|ref|XP_001363945.	Monodelphis domestica
------------------------------------------------------------
-------------MAGW------------------IQAQQLQGDALRQMQVLYGQ-HFPI
EVRHYLAQWIES--QAWNTIDL--D--------------------------------NPQ
DSVQAAQLLEGL----------IQELQKKAEHQ-V----------GEDGF----------
LLKIKLGHYATQLQS--TY-DRCPMELVRCIRHILYNEQRLVRE----------------
--AT--NCS--SPAGNLAD---ALSQKHLQINQTFEELRLVTQD--TENEL-------KK
LQQTQEYFIIQYQESL-RNQAQFSQLSQ-LSPQE--RLTRETALQQKQVSLEAWLQREAQ
TLQQYRVELAEKHQKTLQLLRKQQTII--LDDELIQWKRRQQLAGNGGP---PEGSLDVL
QSWCEKLAEIIWQNRQQIRRAEHLCQQ----LPIPGP-VEEILTELNATITDIISALVTS
TFIIEKQP--------PQVLKTQTKFAATVRLLVGGK--LNVHMNPPQVKATIIS-----
---EQQAKSLL----KNENTR--NDY---SGEILNNCCVMEYHQA-TGTLSAHFRNMSLK
RIK-----------RSDRRGAESVTEEKFTILFESQF--SV----GGNELVFQVKTLSLP
VVVIVHGSQDNNATATVLWDNAFAEPGRVP--FAVPDKVLWPQLCEALNMKFKA--EV--
-----QSNRGLTKENLVFLAQKLFNSSSN-NMEDYNNMAISWSQFNRENLP---------
-GRNYTFWQWFDGVMEVLK-KHLKPHWNDGAILGFVNKQQAHDLLINKP--DGTFLL---
-----RFSDSEI-GGITI---AWKFDSQ--------------------------------
-----------ERMFWNLMPFTTRDFSIRSLADRLGDL----------NYLIYVFPD---
---RPKDEVYSKYYTPVMCESATAKAV-----DGYVKPQIKQVV----------PEFAGA
S------------------------ADSSG------------------------------
---------------------GTATYMDQAP--SPA---VCS-QSHYNM----------Y
PQNPD-------SVLDPDADF----------------DLDDTMDVARHVE-ELLRRPMDS
Q----------------------------WIPHAQS------------
>gi|114667257|ref|XP_001165762.	Pan troglodytes
------------------------------------------------------------
-------------MAGW------------------IQAQQLQGDALRQMQVLYGQ-HFPI
EVRHYLAQWIES--QPWDAIDL--D--------------------------------NPQ
DRAQATQLLEGL----------VQELQKKAEHQ-V----------GEDGF----------
LLKIKLGHYATQLQK--TY-DRCPMELVRCIRHILYNEQRLVRE----------------
--AN--NCS--SPAGILVD---AMSQKHLQINQTFEELRLVTQD--TENEL-------KK
LQQTQEYFIIQYQESL-RIQAQFAQLAQ-LSPQE--RLSRETALQQKQVSLEAWLQREAQ
TLQQYRVELAEKHQKTLQLLRKQQTII--LDDELIQWKRRQQLAGNGGP---PEGSLDVL
QSWCEKLAEIIWQNRQQIRRAEHLCQQ----LPIPGP-VEEMLAEVNATITDIISALVTS
TFIIEKQP--------PQVLKTQTKFAATVRLLVGGK--LNVHMNPPQVKATIIS-----
---EQQAKSLL----KNENTR--NEC---SGEILNNCCVMEYHQA-TGTLSAHFRNMSLK
RIK-----------RADRRGAESVTEEKFTVLFESQF--SV----GSNELVFQVKTLSLP
VVVIVHGSQDHNATATVLWDNAFAEPGRVP--FAVPDKVLWPQLCEALNMKFKA--EV--
-----QSNRGLTKENLVFLAQKLFNNSSS-HLEDYSGLSVSWSQFNRENLP---------
-GWNYTFWQWFDGVMEVLK-KHHKPHWNDGAILGFVNKQQAHDLLINKP--DGTFLL---
-----RFSDSEI-GGITI---AWKFDSP--------------------------------
-----------ERNLWNLKPFTTRDFSIRSLADRLGDL----------SYLIYVFPD---
---RPKDEVFSKYYTPVLAKAV----------DGYVKPQIKQVV----------PEFVNA
S------------------------ADAGG------------------------------
---------------------SSATYMDQAP--SPA---VCP-QAPYNM----------Y
PQNPD-------HVLDQDGEF----------------DLDETMDVARHVE-ELLRRPMDS
L------------------DSRLSPPAGLFTSARGSLS----------
>gi|58865380|ref|NP_001011905.1	Rattus norvegicus
------------------------------------------------------------
-------------MAQW------------------EMLQNLDSPFLDQLHELYSQSLLPM
DVRQHLAAWIED--QNWREAVL------------------------------------GS
DHSKANMLYFNI----------LDQLN-QWDHYSL----------DSDYL----------
LLQHNLRKFNRDIQ---MF-PNGPTQLAEMIFNLLLEEKRILNQ----------------
--AQRAQEM--QPRPAPEAA--GESQQQLEIETRILDLQTAVEA--LVRSI-------RQ
LKDVQDVFSFRYTVLN---------------------HKKTSSLDPHQSQQRQLVQTTAN
ELDRMRKEVLDISKALVGRLTTLVDLL--L-PKLDEWKAQQQKSCIGAP--APELQLDQL
EQWLTAGAKVLFHLRQLLKQLKDMSLM----LRYEGDMFGQGVDLQNAQVTELLQRLLQR
SFVVETQPCMPQTLHRPLILKTGSKFTVRTRLLVRLQE-GNESLK---AEVSIDR-----
---NSELP--------GFRK---------FNILTSNQKSLTPEEGQRQGLIWDFGFLTLV
EQRSVG------AGKGSNKGPLPVTEELHIISAMVEY--VY------QGLKMKLQTDTLP
VVIISNMNQLSIAWASILWFNMLSSTPKDQQFFCKVPKAPWSLLGPALSWQFS----S--
-----YIGRGLDPEQLGMLRNKLFGKNCK-----TEDALLSWADFSKRESP---------
-PGKIPFWTWLDKILELVH-DHLKDLWNDGRIMGFVSRSEERRLLKKMV--SGTFLL---
-----RFSETSE-GGITC---SWVEHQD--------------------------------
---------DDKVLIYSVQPYTKEVLQSLPLTEIIRHYQVLAEENAPENPLRFLYPR---
---VPRDEAFGCYYQEKVNLEER---------RKYLKHRLIVIS--NRQADELQQPLELK
QDPESLELDAELMSVMELARDLELQSMLQV------------------------------
---------------------GLDLGVEPKP--DPT---LSP-APQILLEPDPARALNQL
LPEPDLPQDLQQLNTGEMEIFR---------------NNINIDDVMPYGD-PVLAGQSII
E------------------EAYRSCPSHFDVDGPLIPSED--------
>gi|55741760|ref|NP_999455.1|	Sus scrofa
------------------------------------------------------------
-------------MAGW------------------IQAQQLQGDALRQMQVLYGQ-HFPI
EVRHYLAQWIES--QPWDAIDV--D--------------------------------NPQ
DRAQATQLLENL----------VQELQKKAEHQ-V----------GEDGF----------
LLKIKLGHYATQLQN--TY-DRCPMELVRCIRHILYNEQRLVRE----------------
--AN--NGS--SSAGILVD---AMSQKHLQINQTFEELRLVTQD--TENEL-------KK
LQQTQEYFIIQYQESL-RIQAQFAQLAQ-LNPQE--CLSRETALQQKQVTLEAWLQREAQ
TLQQYRVELAEKHQKTLQLLRKQQTII--LDDELIQWKRRQQLAGNGGP---PEGSLDVL
QSWCEKLAEIIWQNRQQIRRAEHLCQQ----LPIPGP-VEEMLAEVNATITDIISALVTS
TFIIEKQP--------PQVLKTQTKFAATVRLLVGGK--LNVHMNPPQVKATIIS-----
---EQQAKSLL----KNESTR--NEC---SGEILNNCCVMEYHQA-TGTLSAHFRNMSLK
RIK-----------RADRRGAESVTEEKFTVLFESQF--SV----GSNELVFQVKTLSLP
VVVIVHGSQDHNATATVLWDNAFAEPGRVP--FAVPDKVLWPQLCEALNMKFKA--EV--
-----QSNRGLTKENLVFLAQKLFNSSSS-HLEDYSGMSVSWSQFNRENLP---------
-GWNYTFWQWFDGVMEVLK-KHHKPHWNDGAILGFVNKQQAHDLLINKP--DGTFLL---
-----RFSDSEI-GGITI---AWKFDSP--------------------------------
-----------DRNLWNLKPFTTRDFSIRSLADRLGDL----------SYLIYVFPD---
---RPKDEVFSKYYTPVLAPASAAKAV-----DGYVKPQIKQVV----------PEFVSA
S------------------------SDSAG------------------------------
---------------------GNATYMDQAP--SPA---VCP-QAHYSI----------Y
PQNPD-------PVLDQDGEF----------------DLDETMDVARHVE-ELLRRPMDS
L------------------DPRLSPPAGLFASTRGSLS----------
>gi|70571290|dbj|BAE06716.1|	Ciona intestinalis
GDMSIDRTNTDSLSTNLEKEVTNGNQWNDLEATIPPLQPNELQDIFRDVVLDWQAQAELT
EMMDTADIEDTTYVGQW---------------NRVERLSSIRNKVVESMIYKFCQETPML
KFRIMFADVIES--KCWHLIDSNDC--------------------------QPGGINMRR
ASTIVSCLQEAV----------AGRLNDSYMQIRVPIDGGR----GGNLL--------SV
KVKSELLNWEQELRG--RY-TQRPMELVQVMQKMLKREQYILEM----------------
--AEKMPLY--TNEQPQNG---SMSSSPGSAMQKTEPMPDMPRVQYIMRDLNQAELCSRE
ITERIERMVGEYQQLHLCTGGNLQVLDT--------YDPRLIASAEEQRTWKTIIELRDS
LVQTRQVLIHEYHKD--QLFNQLQSLLRRVKCEIAEWKRAEAYLSNGKQV-ADSSDIDQL
EDCCKPLAKLFLQSLDQILKLQHIEVD----NLLKEQENMKMLDYLRQHYENMAKDLVEN
AFIVEKQP--------PQVLMKDKKFMCQLRHLVADG--LSIHQFRFDTQVQLVN-----
---TEAACAIV----DGGPSTPIKP----SGKILNNCHKSDFVEQ-TKQLHVHMRNMSLS
MRQ-----------RGDRGRADCVAEEKFCMVFRAFI--SLRF-PSKAEYDVVAQTFSLP
IVVISHGKQEADAQATVFWDNAFSESVRRP--FEVPDSVPWNWILDGLNCLWKK--ECEK
EPGSASEGIGLTHEAKKYLTVKLLGTDAV-----DPHTHVSWRQFNRENLP---------
-GKGFTFWTWFFKVMELVSSPYVKKFWNLRYITGFIGKAECQNYLLTCP--LGAFMF---
-----RFSDSQL-GALSISCYTYCEKTK--------------------------------
-----------RKEVGHLEPDTIKRLQTRSIPDMVKDL----------DYLLYLGAD---
---IPKDRAFGPYYTPEFRVESAQ---K----HDYWPKSLQVVT----------------
--------------------------KNNG------------------------------
---------------------TTSTFIRSMK--QPNSPDMGP-HVQLKS-----------
--------SMSPPTFGSPG------------------TPLSPLDLLSPNP-SLHGE----
------------------------------------------------
>gi|18859435|ref|NP_571554.1|	Danio rerio
------------------------------------------------------------
-------------MAQW------------------NQLQQLETRYLEQLYHLYSD-SFPM
ELRQFLAPWIES--QDWAY--------------------------------------AAN
KESHATLVFHNL----------LGEIDQQYSRF-L----------QENNV----------
LYQHNLRRIKQHLQS--KY-LEKPMEIARIVARCLWEEQRLLQT----------------
--ATTAQQD--GQVAHPTGT--VVTEKQQILEHNLQDIRKRVQD--MEQKM-------KM
LENLQDDFDFNYKTLK-SAGELSQDLNG---------NSQAAATRQKMSQLEQML----S
ALDQLRRQIVTEMAGLLSAMDFVQKNL--TDEELADWKRRQQIACIGGP---PNICLDRL
ETWITSLAESQLQIRQQIRKLEELQQK----VSYKGDPIIQHRPALEEKIVDLFRNLMKS
AFVVERQPCMPMHPDRPLVIKTGVQFTTKVRLLVKFPE-LNYQLK---IKVCIDK-----
---ESGDVAAI----RGSRK---------FNILGTNTKVMNMEESNNGSLSAEFKHLTLR
EQRCGN------GGRTNSDASLIVTEELHLITFETE----V----YHQGLKIDLETHSLP
VVVISNICQMPNAWASILWYNMLTNHPKNVNFFTKPPVGTWDQVAEVLSWQFS----S--
-----TTKRGLTIEQLTTLAEKLLGPCVN-----YSGCQITWAKFCKENMA---------
-GKGFSFWVWLDNIIDLVK-KYILALWNEGYIMGFISKERERAILSPKP--PGTFLL---
-----RFSESSKEGGITF---TWVEKDI--N-----------------------------
----------GKTQIQSVEPYTKQQLNSMSFAEIIMGYKIMDATNILVSPLVYLYPD---
---IPKEEAFGKYCRPEAHPDTEFPDTGCVT-QPYLKTKFICVT----PCPSVFMDFPDS
ELLGN--------------------GFPGT------------------------------
---------------------NSGNTSDLFP--------MSPRTLDSLM----------H
NEAAE-------ANPGPLESL----------------TLDMELS-SDHAS-PMREGFAAS
T-------------------------VSDMDTCRNA------------
>gi|149715157|ref|XP_001488464.	Equus caballus
------------------------------------------------------------
-------------MSVW------------------GLVLKMPPEKLQRLYV-----DFPQ
HLRHLLGDWLEN--QPWEFLVG--S--------------------------------DAF
CCNMASALLSAT----------LQHLQTLAGEQ------------GEGSA----------
ILQH-----ISTLES--IY-QRDPLKLVATFKHILQGERKAVME----------------
----------------------QFHHLPMPFHRKQEELK-------FNTVL-------RR
LQHRVGETRLLREALK-------------------------QGAEAGQVSLHSLIETPAN
G-SGPSEALATLLQEAVAELEAAQALV--L-KRIQIWKRQQQLAGNGAP---FEESLASL
QERCESLVDIYSQLQQEV-------------GAAGGELEPKTRAVLISRLEEVLRTLVTS
SFLVEKQP--------PQVLKTQTKFQAGVRFLLGLRF-LGAPAKPPVVRADMVT-----
---EKQARELS----MPQGPGAGTES---SGEIINNTVPLENSIP-GNCCSALFKNLLLK
KIK-----------RCERKGTESVTEEKCAVLFSTSF--AL----GPNKLHIQLQALSLP
LVVIVHGNQDNNAKATILWDNAFSEMDRVP--FVVAERVPWEKMCETLNLKFMA--EV--
-----GTNRGLLPEHFLFLAQKIFNDNSL-STEAFQHRSVSWSQFNKEILL---------
-GRGFTFWQWFDGVLDLTK-RCLRSYWSDRLIIGFISKQYVTSLLLNEP--DGTFLL---
-----RFSDSEI-GGITI---AHVIRGQ--D-----------------------------
----------GSSQIENIQPFSAKDLSIRSLGDRIRDL----------AQLKNLYPK---
---KPKDEAFRSHYKPEQMGKDG---------RGYVPATIKMTVERDQPLPTPEPQMPTM
MPTYDLGMAPDSSMNMQLGPDMVPQVYPPHSHSMPSYQGLSREESVSVLPAFPEPHLPMP
PTLSQMSLPFDQPHPQGLLPCQPQEHAVSSP--EPL---LCS-DVTMAEESCLSQPVGGF
PQGTWVSEDMFPPLLPPT-------------------EQDLTKLLLEGQG-ESGGGSLGA
Q------------------PLLQPSPYGQSGISMSHLDLRANPSW---
>gi|156548005|ref|XP_001605495.	Nasonia vitripennis
------------------------------------------------------------
-------------MALW------------------AKAQQLPQEALQKVRSVYGE-HFPI
EVRHFLSSWIEE--KMWTDIEP--D--------------------------------NPQ
YEQYIANLVESL----------IQELETKAASLSN----------TEDLF----------
LTRIKLMEAAKSFRQ--RY-SPHPISLFKIIRHCLVTEMNLVSQ----------------
--VESLGGNIMNMAGSRVG---LVGDSVAEIAQQLDTLRRRTQE--TGEDL-------RK
MEQEQESFAIAYHECT-KLNAHLQNIAT--QPQTQQTIEIEKKIRRQKEQSEQHLNHKVT
TLLQLRLNLADKLKDTISKLSLLQSKV--LDDELIRWKRDQQLAGNGAM---FASNLDAI
QEWCESLAELIWLNRQQVKEADRLKAK----LNLEPPGVQDILPQLNSNITQLLSSLVTS
TFIIEKQP--------PQVMKTNTRFTSTVRLLVGGK--LNVHMTPPQVKVSIIS-----
---EAQANSLL----KSDKMGNKGEA---SGEILNNTGTMEYHQA-TRQLSVSFRNMQLK
KIK-----------RAEKKGTESVMDEKFSLLFQSQF--SV----GGGELVFQVWTLSLP
VVVIVHGNQEPHAWATVTWDNAFAEPGRVP--FAVPDKVPWCQVAEALNVKFR----S--
-----ATGRALTEDNLRFLGEKAFRGGTP-GCQDFTNLLLSWAQFCKEPLP---------
-ERNFTFWEWFYAVMKLTR-EHLRGPWNDGYILGFVRKKQAEEMLATCA--SGTFLM---
-----RFSDSEL-GGVTI---AWVGDQT--------------------------------
-------------EVFMLQPFTSKDFAIRSLADRVSDL----------QHLLYLYPD---
---LSKDQAFSKYYTPFQEQQPLN--------NGYVKPLLVTHV----------PGWSAP
S-----------------------------------------------------------
--------------------------VAHSP--DPSVTRDTP-SVASS-----------Y
APGLG-------QSVRTNA------------------DMDYVELMNHSDL-SSIDENLNL
D------------------QLSTFGPFNEFMQSYNAKPQ---------
>gi|153946362|gb|ABS53147.1|	Salmo salar
------------------------------------------------------------
-------------MAQW------------------CQLQLLESKYQEQVDQLYDD-SFPM
DIRQYLSKWIES--IDWENVAV--------------------------------------
QDSLATVRFHDL----------LAQLDDQHSRF-A----------LENNF----------
LLQHNIRKIKRNLQD--HF-QEDPVHMAMIISRNLKEEQKILAA----------------
--AK-------SIETDRENTQTSMVLEKQKLDNKVKDMKNKVQE--ADQNV-------KS
LEYLQDEHDFKENTLK-NREHEMNGLTQ-----------------KQLEHEKLQIAEMCF
KLKFKRGEVVGQLAEVLNIAEAVQSDL--ISEELAEWKKRQQISCIGGP---PNACLDQL
QNWFTAVAESLQQVRQLLKELQELEQK----YTYDNDPIKQQKGFLEGRALSLFRNLLEH
SLVVERQPCMPTHPQRPLVLKTQVQFTVKLRFLVKLQE-FNYQLK---VKALFDK-----
---DVTEK-------KGFRK---------FNILGTNTKVMNMEES-NGSLAAEFRHLQLK
EQKVA-------GNRTN-EGPLIVTEELHCICFESE----L----NQSGLELKLETISLP
IVVISNVSQLPSGWASILWYNMLTSEPKNLKFFLSPPAASWGQLSEVLSWQFS----S--
-----VTKRGLNEEQLGMLADKLLGQKAQ----RNPEGLVPWTKFCK-SLS---------
-EKSFPFWLWIEAILDLIK-RHLLSLWNDGCILGFVSKEREKALLTGKC--PGTFLL---
-----RFSESSRDGAITF---TWVEHDQ--Y-----------------------------
----------DKPVFHAVEPYTKKELSAVSLPDIIRTYKVMAAENIPENPLRLLYPD---
---IPKDKSFGKYYAGASEASEPMDVESSSS-TGYMKTELISVS----------------
------------------------------------------------------------
-------------------------------------------EVHPSR-----------
-------------------------------------LQDNMMPMSPDVF-GELKRSVRQ
C------------------------PVLDWS-----------------
>gi|147899870|ref|NP_001083890.	Xenopus laevis
------------------------------------------------------------
-------------MAVW------------------IQAQQLQGDALRQMQALYGQ-HFPI
EVRHYLSQWIEA--QTWDSVDP--E--------------------------------NPQ
DNLKATQLLEGL----------VQELQKKADSQ-V----------GEDGF----------
LLKIKLGHYATQFKN--TY-ERCPMELVRCIRHILYHEQRLVRE----------------
--AS--NSS--SPVGGLVD---TMSQKHLQINQTFEELRVITQE--TENGL-------KK
LQQTQEYFIIQYQESL-RIQAQFTQLLQ-LTPQE--RMPREATLQQRQSSLEAWLQREAQ
TLQQYRLDLSEKHQ-SVQLLRKQQTII--LDDELIQWKRRQQLAGNGGP---PEGSLDLL
QTWCEKLADIIWQNRQQIRRAEHLCQQ----FRIPGP-VEELLSELNATITDIISALVTS
TFIIEKQP--------PQVLKTQTKFAATVRLLVGGK--LNVHMNPPQVKATIIS-----
---ELQAKALL----KNENTR--NES---SGEILNNCCVMEYHQA-TGTLSAHFRNMSLK
RIK-----------RSDRRGAESVTEEKFTILFESQF--SV----GGNELVFQVKTLSLP
VVVIVHGSQDNNATATVLWDNAFAEPGRVP--FVVPDKVVWPQLCDALNMKFKA--EV--
-----QSNRGLNDENLVFLAQKLFNSNLS-HKEEYSNMTVSWAQFNRENLP---------
-GWNYTFWQWFDGVMEVLK-KHLKPHWNDGAILGFVNKQQAHDMLVNKR--DGTFLL---
-----RFSDSEI-GGITI---AWKFELP--------------------------------
-----------DRALWNLMPFTARDFSVRSLADRLGDL----------NYLIYVYPD---
---RPKDEVFSKYYTPVLCNPSKT--------DGYVKPQIKQVV----------PEFV--
-------------------------ANDVM------------------------------
---------------------PPSTYMDQAP--SPA---VCS-QSHYNL----------Y
QQNPD-------SVLDPDGDL----------------DLDD-MDVARHVE-ELLRRPMDN
S------------------Q---------WIPHAQS------------
>gi|119351872|gb|ABL63639.1|	Hyphantria cunea
------------------------------------------------------------
-------------MSLW------------------SRAQQLPPDSLQKVRTIYGD-HFPI
EVRHCLAPWIES--RIW----------------------------------------TGE
SEEQQRFFVDEL----------VQEIQAHADMM-I----------SPDMF----------
VTKMKLLDAAKNFHI--TY-SHSQHELFQYMRRALAMEMEVIQN----------------
--A---MGT--PFVAQP-----QTERKYSELITGLQNVRQKVSV--VSEEI-------RG
LQANIESFSLEYHECL-KHKGHMNYLQ---QSMTNDRRDLAACLRVQIEETERKLNATVA
QISQSQLELVDHMKENIANLRQLQSQV--LDEELIKWKREQQLSGNGVP---MQSNLNTI
QEWCELLADLIWTTRQQVNNVARNTKTV---VELRQPHLAEMLDEMSKTVTGLLSTLVTS
TFVIEKQP--------PQVMKTNTRFTATVRLLVGGQ--LNVHMTPPRVSVVIIS-----
---EHQAQLLL----KSETQAGKGKQPVECGDILNNTGTMEYQPT-SRQLSVSFRNMQLR
KIK-----------RAEKKGTESVMDEKLTLLFQSQF--NV----GGGELVFQVWTLSLP
VVVIVHGNQEPHGWATVTWDNAFSPPGRVP--FAVPDKVTWGQLAETLRIKFG----S--
-----ATGGDLSEDNLRFLAEKIFRTSLPMNTMDLNAMAVSWYQFCKDALP---------
-ERNFTFWEWFYMVVKVTR-DYLRTLWCDHLIMGFIQKKQAEDMLSKCP--PGTFLLRFS
DTFLLRFSDSEL-GGITI---AWVGDGN--------------------------------
-------------EVFSLQPFTSRDLMLRSLADRVLDL----------TQLQFLYPN---
---IAKDDVFSKYYTKPENEMLK---------NGYVKPVLVTTL----------PSYMS-
------------------------------------------------------------
---------------------SSPAYAH-----SPDSHRNTP-SVQSSY-----------
------------FSAATPAQT----------------DSFMDSELFEQIR-AFEPDGMDE
F--------------------------DIYSNMSMK------------
>gi|118093373|ref|XP_001231299.	Gallus gallus
------------------------------------------------------------
-------------MSQW------------------SQVQQLEIKFLEQVDQFYDD-NFPM
EIRHLLAQWIES--QDWEA--------------------------------------ASN
NEAMATILLQNL----------LIQVDEQLDRV-S----------QEKNL----------
LLIHNLKRTRKLLQG--KY-HGNPMHIAVIISNCLREERRILAA----------------
--ASMPVQG--PLEKSLQNS--VVSERQRNVEHKVSAIKNSAQM--TDQDV-------KY
LEDLQEEFDFRYKTIQ-SLEQS---------------DKNSALIKQEMLALQAML----N
TLDYKRKEVLSKIGRVIHEIDMLMSNM--LTEELLDWKRRQQIACIGGP---LHGGLDQL
QNCFTLLAESLFQVRRQLEKLDELLTR----LTYDGDPIPVQRPQLMEKVNFLLYNLFRN
SFVVERQPCMPTHPQRPMVLKTLIQFTVKLRLLIKLPE-LNYQIR---VKATIDK-----
---NVSTV--------SNRR---------FVLCGTHVKAMNMDESANGSLSVEFRHLQPK
EMKSSA------GSKGN-EGPHMVTEELHSISFETQ----V----CLYGLTINLETSSLP
VVMISNVSQLPNAWASIIWYNLSTNDPQNLSFFNNPPAATLSQLLEVLSWQFS----S--
-----YVGRGLNSEQLNMLAEKLMGQQVS-----YSDYQLSWAKFCKEHLP---------
-GKSFTFWVWLEAILDLIK-KHILPLWIDGYVMGFVSKEKERILLKDKT--PGTFLL---
-----RFSESNL-GGITF---TWVDQLE--N-----------------------------
----------GEVTFHSVEPYNKGRLAALPFADILRDYKVIMADNVPENPLKYLYPD---
---IPKDKAFGKHYSCQPNEVSKPSDGGV---KGYVPSVFIPVS--KILNDSTDPHSPSD
LLPMSPSVYAVLREHLSPTAIETALAFPCFSSEKNSFSWRSWQPG---------------
---------------------QAYSPLDKIWLEDWAQRTVCYRPRGLSL----------I
PETPA-----YPRNRTALGA-----------------TLLATLSSLTRKE-ESRGRSARQ
CRVRPLVQAAWAGLPLAPRRVPMAASVRVFLGAGKKRERSGGAVCSSG
>gi|45385788|gb|AAS59771.1|	Cervus elaphus
------------------------------------------------------------
-------------FSL--------------------------------------------
------------------------------------------------------------
----------------------------------------------ENNF----------
LLQHNIRKSKRNLQD--NF-QEDPILMSMIICNCLKEERKILDH----------------
--AQRISQA--QSGNIQST---VMLDKQKELDSKVRNVKDKVMS--IEHEI-------KT
LEDLQDEYDFKCKTLQ-NREHETNGVAK-----------------NDQKQEQLLLQKMYL
MLDNKRKEVVLKIIELLNATELTQKAL--INDELVEWKRRQQSACIGGP---PNACLDQL
QNWFTIVAESLQQVRQQLKKLEELEQK----YTYEHDPITKNKQALWDRTFNLFQQLIQS
SFVVERQPCMPTHPQRPLVLKTGVQFTVKLRLLVKLQE-LNYNLK---VKVLFDK-----
---DVNERNTV----KGFRK---------FNILGTHTKVMNMEESTNGSLAAEFRHLQLK
EQKNA-------GARTN-EGPLIVTEELHSLSFETQ----L----CQPGLVIDLETTSLP
VVVISNVSQLPSGWASILWYNMLVAEPRNLSFFLNPPCARWSQLSEVLSWQFS----S--
-----VTKRGLNVDQLNMLGEKLLGPNAG------PDGLIPWTRFCKENIN---------
-DKNFPFWLWIESILELIK-KHLLALWNDGCIVGFISKERERALLKDQQ--PGTFLL---
-----RFSESCREGAITF---TWVERSQ--N-----------------------------
---------GGEPYFHAVEPYTKKELSAVTFPDIIRNYKVMAAENIPENPLKFLYPN---
---IDKDHAFGKYYSRPKEAPEPMELDGPKG-TGYIKTELISVS----------------
------------------------------------------------------------
------------------------------------------------------------
---------------------------------------------------EV-------
------------------------------------------------
>gi|74005112|ref|XP_536007.2|	Canis familiaris
------------------------------------------------------------
-------------MSQW------------------NQVQQLEIKFLEQVDQFYDD-NFPM
EIRHLLAQWIEN--QDWEA--------------------------------------ASN
NETMATILLQNL----------LIQLDEQLGRV-S----------KEKNL----------
LLIHNLKRIRKVLQG--KF-HGNPMHVAVVISNCLREERRILAA----------------
--ANMPVQG--PLEKSLQSS--SVSERQRNVEHKVAAIKNSVQM--TEQDT-------KY
LEDLQDEFDYRYKTIQ-TMDQ---------------GDKNNALMNQEVLTLQEML----N
SLDFKRKEALSKMTQIVNETDLLMNSM--LMEELQDWKRRQQIACIGGP---LHNGLDQL
QNCFTLLAESLFQLRRQLEKLEEQSTK----MTYEGDPIPMQRAHLLERVTFLIYNLFKN
SFVVERQPCMPTHPQRPMVLKTLIQFTVKLRLLIKLPE-LNYQVK---VKASIDK-----
---NVSTL--------SNRR---------FVLCGTHVKAMSIEESSNGSLSVEFRHLQPK
EMKSSA------GSKGN-EGCHMVTEELHSITFETQ----I----CLYGLTIDLETSSLP
VVMISNVSQLPNAWASIIWYNVSTNDSQNLVFFNNPPSATLSQLLEVMSWQFS----S--
-----YVGRGLNSDQLNMLAEKLTAQSS------YNDGHLTWAKFCKEHLP---------
-GKSFTFWTWLEAILDLIK-KHILPLWIDGYVMGFVSKEKERLLLKDKM--PGTFLL---
-----RFSESHL-GGITF---TWVDHSE--N-----------------------------
----------GEVRFHSVEPYNKGRLSALPFADILRDYKVIMAENIPENPLKYLYPD---
---IPKDKAFGKHYSSQPCEVSRPTERGD---KGYVPSVFIPIS--TIRSDSAEPHSPSD
LLPMSPSVYAVLRENLSPATIETAVCSLSFPLLVKGTPVKHMCYLLLVPLPGMTSSQGKG
SIIILSWYS------------QTEGPAEKKPHGCPGLMILEGLTGLRTLGLRAPGRQVSS
AFTDAQQTRGVLRASHLDHKT----------------QSVICLTIFPAVPMPIRGRSTCT
GETGAATRAPRGTRPDSPPEPGTAVTGQSFLLCGEMKTHKRQVIK---
>gi|82590416|gb|ABB84488.1|	Macaca fascicularis
------------------------------------------------------------
-------------MAVW------------------IQAQQLQGEALHQMQALYGQ-HFPI
EVRHYLSQWIES--QAWDSIDL--D--------------------------------NPQ
ENIKATQLLEGL----------VQELQKKAEHQ-V----------GEDGF----------
LLKIKLGHYATQLQN--TY-DRCPMELVRCIRHILYNEQRLVRE----------------
--AN--NGS--SPAGSLAD---AMSQKHLQINQTFEELRLVTQD--TENEL-------KK
LQQTQEYFIIQYQESL-RIQAQFGPLAQ-LSPQE--RLSRETALQQKQVSLEAWLQREAQ
TLQQYRVELAEKHQKTLQLLRKQQTII--LDDELIQWKRRQQLAGNGGP---PEGSLDVL
QSWCEKLAETIWQNRQQIRRAEHLCQQ----LPIPGP-VEEMLAEVNATITDIISALVTS
TFIIEKQP--------PQVLKTQTKFAATVRLLVGGK--LNVHMNPPQVKATIIS-----
---EQQAKSLL----KNENTR--NDY---SGEILNNCCVMEYHQA-TGTLSAHFRNMSLK
RIK-----------RSDRRGAESVTEEKFTILFESQF--SV----GGNELVFQVKTLSLP
VVVIVHGSQDNNATATVLWDNAFAEPGRVP--FAVPDKVLWPQLCEALNMKFKA--EV--
-----QSNRGLTKENLVFLAQKLFNNSSS-HLEDYSGLSVSWSQFNRENLP---------
-GRNYTFWQWFDGVMEVLK-KHLKPHWNDGAILGFVNKQQAHDLLINKP--DGTFLL---
-----RFSDSEI-GGITI---AWKFDSQ--------------------------------
-----------ERMFWNLMPFTTRDFSIRSLADRLGDL----------NYLIYVFPD---
---RPKDEVYSKYYTPVPCESATAKAV-----DGYVKPQIKQVV----------PEFVNA
S------------------------ADAGS------------------------------
---------------------GSATYMDQAP--SPA---VCP-QAHYNM----------Y
PQNPD-------SVLDTDGDF----------------DLEDTMDVARRVE-ELLGRPMDS
Q----------------------------WIPHAQS------------
>gi|115942976|ref|XP_781834.2|	Strongylocentrotus purpuratus
------------------------------------------------------------
-------------MSLI------------------MKLQQLQGGDLEKLQGLYQNLEFPM
EIRYYCAHWIEA--QNWSSIDI--D--------------------------------NPV
FEPDAIDLLHGM----------IKQVQAKIEEL-S----------DDEMF----------
PIKLKLNNFTQELNK--RF-SNQPFAFVRLINHCLESEERLVQN----------------
--SMNRTVE--SP---------QAPPCNKDITENITNIRMMTQK--TEEDL-------SN
LQQKQEMFVFQYQENL-RFQGRLNQLANSLAESDPNRRAEEVSLRKKKAEVEQVLQTEAQ
ELLRMRMDLAEKHRKTLYSLKILQSRV--LEDELIRWKRQQQLAGIGGP---PEGTLDQQ
QCWCEALAELIWHNRQQVKKVELLRQQ----LPIPVPHGQDLLPELNRCFMAQLSTLVTS
TFIIEKQP--------PQVLKKETRFSASVRLLVGGK--LNVHMNPPQVKATIIS-----
---ESQAKAVL----ASETSS-WNET---SGDILNNCGVMEYHRE-TGVLNVTFRNMSLK
RIR-----------RADRRGSEFVTEEKFTILFQSQF--SV----ASGELVFQVRTMSLP
VVVIVHGNQESNALATVLWDNAFASSGRVP--FVVPDGVPFADMGRALNSKFM----L--
-----ANGRSLSDANLLYLAQKAFNHNVG-QTEDFSNVYITWSIFNRDPLP---------
-NRTFTFWRWFHGVLELTR-KHLRGPWNDGSIMGFVSRSMAHDLLLSQQ--VGCFLL---
-----RFSDSEI-GGITI---AWLAEDA--------------------------------
---------NTERQVYNLQPFTADDFNIRSLADRIHDL----------SHLTHLYPD---
---KPKDTAFGQYYTTDPEVPPQGD-------GGYVPTSLVSHI----------PHMPG-
-------------------------GPPQH------------------------------
---------------------HSQEMGNREPMSPPS---QQL-MTSSSL----------R
VSSSD----GMVGTTSMDQNL----------------DPLEELPILEDYD-DPQAGIMED
L------------------LR--------WSASTS-------------
>gi|91083609|ref|XP_969477.1|	Tribolium castaneum
------------------------------------------------------------
-------------MSLW------------------AKAQQLPPESLQQIRSIYGD-HFPI
EVRHYLAHYIEE--KFWSDIDPVPD--------------------------------NPQ
HEQYVAGLVNSL----------IQEVENKAAVV-N----------DAEYF----------
LTKLKLAEAAKMFRQRYRY-NSNPMQLFSYVRQCLATEMRLVQA----------------
--AN---GE--ALTGLANL---VISNSGTEVLHKIDILRRRTQD--TADDL-------RR
MEQEQESFALQYHECT-KINAHIQQLSS-QQPTNAQTTATVQKLTRQKEMLEQVLNQKVA
GLMQLRLAIVDKFKETIQLLNQLQSNI--LDDELIRWKREQQLAGNGAN---FNSNLDTI
QDWCESLAELIWLNRQQIKEVDRLRQK----LSLDPPGVADLLPQVLGDVTQLLSSLVTS
TFIIEKQP--------PQVMKTNTRFTATVRLLVGGK--LNVHMTPPQVKVTIIS-----
---ESQANVLL----KNDKLAKSGEC---SGEILNNTGTMEYQQA-TRQLSVSFRNMQLK
KIK-----------RAEKKGTESVMDEKFSLLFQSQF--SV----GGGELMFQVWTLSLP
VVVIVHGNQEPHAWATVTWDNAFSDAGRVP--FSVPDKVLWTNVAETLSLKFR----A--
-----ATGRPLNEDNLRFLADKAFRGNYN----EGSNPMLSWAQFCKEPLS---------
-ERNFTFWEWFYAIMKLTR-EHLRGPWVDGAIIGFVKKKQAEEMLASCP--CGTFLL---
-----RFSDSEL-GGITI---AWVSDTG--------------------------------
-------------EVFSLQPFTSKDFAIRSLADRIADL----------NHLIYLYPD---
---ISKEIPFGKYYTPFQDNQPTSN-------NGYVKPVLVTHV----------PGLSAA
-------------------------SYPNT------------------------------
---------------------PQHSFLQ-----SPDPSRDTP-SVASS-----------Y
AGSIATTTTAGGPAMDYLEQL----------------DECNLDLGLVNFN-ELMQGYKQ-
------------------------------------------------
>gi|29540612|gb|AAO88245.1|	Carassius auratus
------------------------------------------------------------
-------------MALW------------------NQLQLLDSLYLEQVDQLYDE-AFPM
EIRQYLSQWIES--HDWES--------------------------------------VAS
NVSLATLRFHEL----------LNQLDEHYSRL-N----------LGNNF----------
LLQHNIRKIKRNLQE--HF-QEDPVHMAMIIANTLNEERKILET----------------
--ALSLQGKGDSSQGS------FMMEQQNELANKINNLKTSVQE--IEQDI-------QV
LEDVQDEYDFKRKTLQSRVEAEMNSQKT-----------------KEIQLEEMAIRQMFI
GLGMKREVVIREMANVLTLAEQIQFTL--ISDELPEWKKRQQMACIGGP---PNACLDQL
QSWFTVVAECLQQIRQQLKKVQELVQK----FTYNNDPLTLGKSQLDEQALSLFKNLILN
SLVVERQPCMPTHPQRPLVIKTGVQFTVKIRSLVKLAE-LNCQLK---VKVFIDK-----
---DLTESDTL----KGCRK---------FNILGTTSKVMNLEES-NGCLAAEFRHLQLK
EMK-C-------NNRTN-ETPLIISEELHLLRFETQ----L----IQPELCVDLSIISLP
VVVISHVNQLPSAWGSILWYNMLCSEPHNLTFFLNPPPVKWEQLSKVISWQFS----S--
-----VTKRALNSEQLRMLANKLLGHEAQ----GDPEGLIYWNTFCKMSSN---------
-ERGVPFWLWIDGILDLIK-KHLLNIWNDGHIIGFLSKGQEKALLRDKL--PGTFLL---
-----RFSETCREGGITI---TWVEYSK--N-----------------------------
----------GEPKMHSVKPYTKSDLASISLPNVIRDYTLTAAEKVPVNPLIYLYPD---
---IPKDEAFSRYYTSAPDDSEEMETDNPI--KPYIPRRMISVS----------------
------------------------------------------------------------
------------------------------------------------------------
---------------------------------------------------ENPVSRLQK
C-----------------------------------------------
>gi|67906114|dbj|BAE00060.1|	Mesocricetus auratus
------------------------------------------------------------
-------------MAQW------------------ETLQNLDSPFLDQLHQLYSQSTLPM
DVRQHLAAWIED--QNWREAVL------------------------------------GN
DQSKANMLYFTI----------LDQLN-QWDHC-S----------DPDCF----------
LLQHNLRKFSRDIQ---TF-PNGPTQLAEMIFNLLLEEKRILNQ----------------
--AQRSQEV--QASPAPEA---AVGSQQLEIESRVLDLQATVEV--LVRSV-------RQ
LKDLHDVFSFRYTVLT-Q-------------------KKKTPSLDPHQNQELQMVQATAN
ELDRMRKEVLDMSRAQVGRLTTLVDLL--L-PKLDEWRVQQQRSCIGAP--PPELQLEQL
EQWLTAGAKLLFHLRQLLKQLKEMSHM----LKYDGDMFSKGVDLQNAQVTELLQRLLQR
SFVVETQPCMPQTLHRPLILKTGSKFTVRTRLLVRLQE-GNESLK---AEVSIDR-----
---NSELP-------PGFRK---------FNILTSNQKTLTPEEGQRQGLVWDFGFLTLV
EQRSVG------TGKGTNKGPLAVTEELHVVSFVVQY--VY------QGLKMELQTDTLP
VVIISNMNQLSIAWASVLWFNMLSPTPQDPRFFCHAPKAPWSLLGPVLSWQFS----S--
-----YVGRGLSSEQLGMLKNKLFGKNCK-----MEDALLSWVDFSKRDSP---------
-PGKIPFWTWLDKILELVH-DHLKDLWNDGHIMGFVSRNQERRLLKKTV--SGTFLL---
-----RFSETSE-GGITC---SWVEHQD--------------------------------
---------DDKVVIYSVQPYTKEVLQSLPLTEIIRHYQVLAEENIPENPLRFLYPR---
---IPRDEAFGCYYQEKVNFEER---------RKYLKHRLIVVSNRQVDELQQPLGLEQE
PELDSLDLNAELTSATTLEQDLELQMLLKE------------------------------
---------------------GLDLGAELEL--NPT---LCV-ASQTVLRADPGPV---S
QPSPDSDLPHDLQQLNMDIFR----------------NNINIDDIMPYGD-PLLADQNIV
D------------------EAYMSCQSHFDVDGPLIPSDD--------
>gi|118404374|ref|NP_001072935.	Xenopus tropicalis
------------------------------------------------------------
-------------MAQW------------------YELQQIDTKFLEQVHQLYDD-SFPM
EIRQYLAQWLES--QDWEH--------------------------------------AAN
NVSLATILFHGL----------LSQLDDQYSRF-S----------LENNF----------
LLQHNIRKSKRNLQD--HF-QEDPVQMAMIINSCLREESKILGN----------------
--ARAYNKN--QVGSTQTT---VMLDKQKELDKKVTDVRNRALE--VEQDV-------KL
LEDLQDEYDFKYKTVQ-SRENEHNGLAQ-----------------NELKKEKMLLSNMHI
HVLLKRKAIIHKIAELMSVTDHTQNAL--INEELVEWKHRQQIACIGGP---PNACLDQL
QSWFTTIAKSLQQVRQQLKKLEELEQK----LTYDGDPITCNKQALQERTQSLFKQLLQS
SFVVERQPCMPTHPQRPLVLKTGVQFTVKLRLLVKLQE-LNYQLK---VKALFDK-----
---DVNDKNIV----KGFRK---------FNILGTHTKVMNMEESTNGSLAAEFRHLQLK
EQKNA-------GSRTN-EGPLIVTEELHCLSFETQ----L----CQLGLVVDLETSSLP
IVVISNVSQLPSGWASILWYNMLTSETKNVSFFLNPPAARWPLLSDVLSWQFS----S--
-----VTKRGLNADQLSMLGEKLLGPTTS-----SGDDLIPWTRFCKENIN---------
-DKNFPFWLWIEGILELIK-KHLLCLWNDGFIVGFISKERERALLKEKA--PGTFLL---
-----RFSESSKEGAITF---TWVERPQ--------------------------------
---------------------NGKEICI-----------------------LFVHKQ---
---KN---------------------------QGFYCTSFLSW-----------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------
>gi|17225564|gb|AAL37476.1|AF32	Spodoptera frugiperda
------------------------------------------------------------
-------------MSLW------------------ARAQQLPPESLQKVRTIYGD-HFPI
EVRHCLAPWIES--RIW----------------------------------------TAE
PEDQQRFFVDEL----------VQEIQAHADLM-L----------SPDMF----------
VTKMKLLDAAKNFHM--QY-SHAPHELYAYMRRSLALEMDVIQN----------------
--A---MGT--PYVAQP-----QTERKYSELITGLQTVRQKVSM--VGEEI-------RS
LQANIESFSLQYHECL-KNKGHMNYLQ---QSMTNERRDLVACLRVQIEETERKLNALVA
QISQSQMELVDHMKEDIANLRQLQSQV--LDEELIKWKREQQLSGNGVP---MQSNLNTI
QEWCELLADLIWTTRQQVNNVARINTKT--IVELRQPHLAEMLDEMSKQVTGLLSTLVTS
TFVIEKQP--------PQVMKTNTRFTATVRLLVGGQ--LNVYMTPPRVNVVIIS-----
---EQQAQLLL----KSETQAGKGKQPVECGDILNNSGSMEYQPT-SRQLSVGFRNMQLR
KIK-----------RAEKKGTESVMDEKLTLLFQSQF--NV----GGGELVFQVWTLSLP
VVVIVHGNQEPHGWATVTWDNAFSPPGRVP--FAVPDKVTWGQLAETLRIKFC----S--
-----ATGGDLSEDNLRFLAEKIFRTSLPLNNIELNAMPVSWTQFCKDALP---------
-ERNFTFWEWFYMVVKVTR-DYLRTLWCDHLIMGFIQKKQAEEMLSKCP--AGTFLL---
-----RFSDSEL-GGITI---AWVGEGN--------------------------------
-------------EVFSLQPFTSRDLMLRSLADRVLDL----------TQLQFLYPN---
---IAKDDVFSKYYTKPENEMLK---------NGYVKPVLVTTL----------PPYMS-
------------------------------------------------------------
---------------------SSPAYAH-----SPDSHRNTP-SVQSSY-----------
------------FSAATPAQT----------------DSFMDSELFEQIR-AFEPDGMDE
F--------------------------DIYSNMSMK------------
>gi|119115376|ref|XP_311053.3|	Anopheles gambiae
------------------------------------------------------------
-------------MSLW------------------ARVNQLPQPILEQIRFIYGS-NFPI
EVRHYLADWIEE--RLLNAPVYTND-------------------------------QEAV
YEQDAANFLNQL----------IMELERTAINL------------PESNF----------
TIKIRLNESARNFRQ--LF-SHNPAQLYQHLMNCLHRERQCVAY----------------
-----------PDECVN-----VQDPEVTEVFNAVQQLQIMVRT--NENDN-------RN
LMKEYEHLLLE------------------------------------LAQHQKMVNDRLQ
LCTGKRLALVDGFRKTILITDEVQNKV--LNKYLSQWKINQGFAGNGASM-MSASNLDTI
QAWCESLAEIIWSTKDQIRLAIKNKSK----LHVEQEDVPDLLPQAMVDVTNLLKMLITN
TFIIEKQP--------PQVMKTNTRFAATVRLLVGNT--LNIKMVNPQVKVSIIS-----
---EAQAQQTQ----QTNKASEQS-----CGEIMNNIGNLEYNET-TKQLSVSFRNMQLK
KIK-----------RAEKKGTECVMDEKFALLFQSSF--AV----GHGDLVFSVWTISLP
VVVIVHGNQEPQSWATITWDNAFADINRIP--FQVPDKVIWNQLAEALNMKFR----A--
-----STGRSLTAENMHFLCEKAFKTNLP--FPVPNDLTIMWSQFCKEPIP---------
-DRSFTFWDWFYAAMKVTR-EHLRGPWMDGSIIGFIHKSKAEDYLLKCP--RGTFLL---
-----RFSDSEL-GGITI---AWVNEGN--D-----------------------------
----------GQPQILHIQPFTAKDFSTRSLSDRIRDF----------DDLFYLYPN---
---KPKHEAFDRYTTPAGPPRNK---------NYIASEVRAVLM----------PGPTNN
QMN----------------------SFP--------------------------------
---------------------NTPSYNIQ----SPDASRDTP-STGYGQ-----------
------------TNYGQVPDF----------------ELENIGMFSSQYH----------
------------------------------------------------
>gi|10197602|gb|AAG14946.1|AF14	Oncorhynchus mykiss
------------------------------------------------------------
-------------MAVW------------------IQAQQLQGDALHQMQSLYGQ-HFPI
EVRHYLSQWLEG--QLWDVIDL--E--------------------------------NPQ
EEFKAKRLLDSL----------IQELQNKAEHQ-V----------GEDGF----------
LLKIKLGHYASQLKS--TY-DRCPLELVRCIKHILYTEQRLVRE----------------
--AS--NSS--SPVGGMMD---SMSQKYQQINQAFEELRLLTQD--TENDL-------RK
LQHNQEYFIIQYQESL-RIQAQLTSLTT-LPPAD--RQLREPTLLSKRATVEAWLTREAN
TLQKYRLDLAEKHQKSLQLLRKQQTII--LDDELIHWKRRQQLAGNGGP---PEGGLDIL
QSWCEKLAETIWQNRQQIRRAEHLRQQ----LPIPGP-IEELLNDLNSTITDIISALVTS
TFIIEKQP--------PQVLKTQTKFAATVRLLVGGK--LNVHMNPPQVKATIIS-----
---EQQAKALL----KNENTR--NDS---SGEILNNNCVMEYHQA-TGTLSANFRNMSLK
RIK-----------RSDRRGAESVTEEKFTILFESQF--SV----GGNELVFQVKTLSLP
VVVIVHGSQDNNATATVLWDNAFAEPGRVP--FIVPDKVLWPQLCEALNMKYKA--EV--
-----QSNRGLSEENLVFLAQKAFSSSSI-NPDDYRGMTMTWSQFNRESLP---------
-GRNFTFWQWFDGVMELTK-KHLKPHWNDGAILGFVNKQQAQDMLMSKP--NGTFLL---
-----RFSDSEI-GGITI---AWVAENPNKP-----------------------------
----------GERMVWNLMPYTTKDFSIRSLADRISDL----------NHLLFLYPD---
---RPKDEVFSKYYTPPLSKAV----------DGYVKPQIKQVV----------PEFTTT
N------------------------PDPA-------------------------------
---------------------ANPTYMDHGA--SPV---VSH-PPNYGI----------Y
QPMSD-------SILDADGDF----------------DLDDTMDVARHVE-ELLRRPMEN
Q----------------------------WSGQQS-------------
>gi|48733790|gb|AAT46364.1|	Oryzias latipes
------------------------------------------------------------
-------------MAQW------------------NQLQQLETRYLEQLYHLYSD-SFPM
ELRQFLAPWIES--QDWAY--------------------------------------AAN
KESHATLVFHNL----------LGEIDQQYSRF-L----------QENNV----------
LYQHNLRRIKQHLQS--KY-LEKPMEIARIVARCLWEEQRLLQT----------------
--ATSTSQD--GSAAHPTGT--VVTEKQQILEHNLQDIRKRVQD--MEQKM-------KM
LENLQDDFDFNYKTLK-SQGELNQDLNG---------NSQAAATRQKMAQLEQML----S
ALDQLRRQIVTEMGGLLTAMDYVQKNL--TDEELADWKRRQQIACIGGP---PNICLDRL
ETWITSLAESQLQIRQQIKKLEELQQK----VSYKGDPIIQHRPALEEKIVDLFRNLMKS
AFVVERQPCMPMHPDRPLVIKTGVQFTNKVRLLVKFPE-LNYQLK---IKVCIDK-----
---ESGDVAAI----RGSRK---------FNILGTNTKVMNMGESNNGSLSAEFKHLTLR
EQRCGN------GGRTNSDASLIVTEELHLITFETE----V----YHQGLKIDLETHSLP
VVVISNICQMPNAWASILWYNMLTNHPKNVNFFTKPPVGTWDQVAEVLSWQFS----S--
-----TTKRGLTIEQLTTLAEKLLGPSVN-----YSGCQITWAKFCKENMA---------
-GKGFSFWVWLDNIIDLVK-KYILALWNEGYIMGFISKERERAILSPKP--PGTFLL---
-----RFSESSKEGGITF---TWVEKDI--S-----------------------------
----------GKTQIQSVEPYTKQQLNSMSFADIIMGYKIMDATNILVSPLVYLYPD---
---IPKEEAFGKYCRPEAAHEPEAGGDSASITQPYLKTKFICVT----PCPSVFMDLPDS
ELLGN--------------------GFPGT------------------------------
---------------------NSGNTSDLFPMMSPR-------TLDSLM-----------
HNEPE-------AHSGHLDSI----------------TLDMDVASPM-------------
------------------------------------------------
>gi|37595925|gb|AAQ94739.1|	Penaeus monodon
------------------------------------------------------------
-------------MSLW------------------NRAQQLPADDLRRVQGIYGE-QFPI
EVRHYLAGWIEDKMQQWNEIDP--D--------------------------------NPS
HSQYAQSLVSQL----------IQEIENKALSYAN----------NEDLF----------
LVRMRLDEAATSFRT--RYLNSNPLGLVGIIRQCLNTEHNLVQQ----------------
--NENMLG---GGVSHATN---MVIEPCAEIEQELRILHERTRE--TANEL-------RH
LEQEQESFALQYHDCA-KINAHLSHIQS--QERTQQNREMEQSLRRRKELGEQQLAQKVS
GLLQLRMALADKHKGTIDRLNSLQQRI--LDEELINWKRDQQMHGNGKPF-NPN-KLDQI
QEWCEALAEIIWLNRHQIKECERHQTK----IPITPPGGVDMLPTLNSHITRLLSSLVTS
TFIIEKQP--------PQVMKTNTRFTATVRLLVGGK--LNVNMTPPQVRVSIIS-----
---EAQANALL----KNDQM-NKGEQ---SGEILNNTGTMEYNQT-SRQLSVSFRNMQLR
KIK-----------RAEKKGTESVMDEKFSLLFQSQF--SV----GGGELVFQVWTLSLP
VVVIVHGNQEPHAWATVSWDNAFAEQGRIP--FTVPEKVPWPQIADMLDTKFK----A--
-----ATGRGLTEDNLKFLAGKAFRNPQV---QDFTNMMLSWSQFCKEPLS---------
-ERNFTFWEWFFAVMKVTR-EHLRQQWNDGSIMGFVGRRQAKEMLKNSK--SGTFLL---
-----RFSDSEL-GGVTI---AWMYEDTTKA-----------------------------
----------CQRDVFMLQPFTSKAFAIRPLADVIADL----------NYLLYLYPN---
---VPKDQAFGKYYTPLGEQQPTTN-------NGYVKPQLKTHV----------PGWSGD
PMD----------------------SYPNT------------------------------
---------------------PQTMYGGMGG--PPS---VSSNPSDCVS-----------
------------TDQKPTLDS----------------PLFDAANVLSDFS----------
------------------------------------------------
>gi|42601300|gb|AAS21327.1|	Oikopleura dioica
------------------------------------------------------------
------MPAETSGVSLW------------------SRVRELEGDALRQIQSLYDT-NFPI
EFRHYFAEIIER--QPWDQIDP--D--------------------------------QSS
DETQAKFILDNF----------LGEINRQCELL-S----------DGGDF----------
LQRLRFSEIGQHFKN--VY-GNHPMELVRIVKKILSIETRLVQE----------------
--ATAANVN--GQDDVKPS---TGSDKNAKINKDLEHLYALTQD--AESDL-------RK
LQSKQEYFVINYQESV-KIQTSLQQINQ-MSASDPTRAQLGQQLTKKKNEVDQLLQLEAH
KLLQQRTSLAEKHHKTFTLLTELQNQV--LDEELIQWKRSQALAYNGVI---QEGSLDQL
QQWCERLAEIIWQCRQQIKRVELQRQQ----LPINNQ-GVDLLPELNTTITALLSTLVTS
TFIIEKQP--------PQVLKTQTRFGSTIRLLVGGK--LNVHMNPPTVKGTVDKRLDFK
NDFDAQAKALL----KNENGRALSET---SGEILNNSSIMEYHPQ-SGVLSVNFRNMSLR
RIK-----------RSDKRGAESVTEEKFTILFQSQF--SV----GGNELVFQVRTLSLP
VVVIVHGNQEANATASILWDNAFAEQGRIP--FQVPDKVAWNRIVETLNYKWKH--EC--
-----QSAHGLTAGAMRYLSQKLFRQPLA----PLSEKPVSWAQFNREPLP---------
-GRNFTFWQWFNGVMELTKSKHVQPHWLDRGCVGFICKNESQEALIQKP--GGSFLL---
-----RYSDSEI-GGLTI---AWVSEND--------------------------------
--------------NKQKQPHTSKDFTVRGLADRIRDL----------EQLHFVYTQDER
I--VGKEEMFSRYYSKSPNPPSQPN-------DGYVKAEIQVTI----------PNIAGI
NLGSPVHESSV--------------ASPRS------------------------------
---------------------PSSGYGDHQSLISSP---QAG-PVQYEMPNQISQDQMDF
SENAQQSNSGSGSAFDPQNSF----------------DQFDSSNTI-DVN-ELLSKVN--
------------------------------------------------
>gi|48141041|ref|XP_397181.1|	Apis mellifera
------------------------------------------------------------
-------------MSLW------------------AKAQQLPQDALQQVRSVYGE-HFPI
EVRHFLSSWIEE--KMWTDIEP--D--------------------------------NPQ
YEQYIATLVRSL----------IQELETKAASL-N----------TDDMF----------
LTKLKLMEAAKNFRQ--RY-THNPAALFRIIRHCLGTEMKLVAQ----------------
--VENVGGTLMNMAGGKVG---LISDAVAEIAQHVESLRRRTQE--TGEDL-------RK
MEQEQEAFAISYHECT-KLNAHLQHFAT--QPQNQQNLDMEKKIRRQKEQQEQLLNHKVA
GLMQLRLTLADKLKDTITRLNSLQSRV--LDDELIRWKRDQQLGGNGAP---FNNNLDSI
QEWCESLAELIWLNRQQIKEAERLKQK----FALEPPGMQDILPTLNSQITQLLSSLVTS
TFIIEKQP--------PQVMKTNTRFTSTVRLLVGGK--LNVHMTPPQVKVSIIS-----
---EAQANALL----KSDKMAKNGEA---SGEILNNTGTMEYHQA-TRQLSVSFRNMQLK
KIK-----------RAEKKGTESVMDEKFSLLFQSQF--SV----GGGELVFAVWTLSLP
VVVIVHGNQEPHAWATVTWDNAFAEPGRVP--FAVPDKVPWGQVAEALNVKFK----S--
-----ATGRALTEDNLRFLAEKAFRGGNA-SGQDYSSLLLSWAQFCKEPLP---------
-ERNFTFWEWFYAVMKLTR-EHLKNPWVDGYILGFVRKRQAEEMLANCA--SGTFLM---
-----RFSDSEL-GGVTI---AWVGDQT--------------------------------
-------------EVFMLQPFTSKDFAIRSLADRVFDL----------QHLLYLYPD---
---ISKDQAFSKYYTPFTENQSTST-------NGYVKPFLVTHV----------PGWGGP
GVGGQTPSHSSVVGVGSSGQSGPGSSYPAT------------------------------
---------------------PSTMFQAHSP--DPSVTRDTP-SVASS-----------Y
APGLG-------QSSVGRTNS----------------DMDYVELMGHPEL-PSIDENLNL
D------------------HFS----FNEFIQTYNTKPQ---------
>gi|47218571|emb|CAG10270.1|	Tetraodon nigroviridis
------------------------------------------------------------
-------------MSQW------------------GQLQMLDCKYLEQVDQLYDD-TFPM
DIRQYLSRWIES--IDWETVAM--------------------------------------
QDSLAMVRFHDL----------LAQLDDQHSRF-A----------LENKF----------
LLQHNIRKIKRNLQD--RF-QEDPVHMAMIISRNLKEEQRILDV----------------
--AKSTEQE--GVGVSS-----TMVVEKQKLDAKVKEMKDSVLM--ADQSI-------KN
LEDQQDEYDFKINTLK-NRENEMNGMTA-----------------KELEKEKLTVNRMCL
ELKAKRQDAVLQLTDLLNVIQALLADL--INEELPEWKQRQQIACIGGP---PNACVDQL
QNWFTAVAESLQQVRQHLKKLQELEQK----LTYESDPITQKKAFLEARALELLKNILSS
SLVVERQPCMPTHPHRPLVLKTGVQFTVKLRFLVKLQE-FNYQLK---VKALFDK-----
---DVVEK-------KGFRK---------FNILGTNTKVMNMEES-NGSLAAEFRHLQLK
EQKVA-------GNRTN-EGPLIVTEELHSLSFESEL--HL----NQSGLSIKLEAISLP
VIVISNVCQLPSAWASTLWYNMLTTEPKNLKFFLNPPQAKWSQLSQVLSWQFS----S--
-----ITNRGLNQEQLNMLADKLLGAKAQ----RNPEGLIPWTKFCKAEDPLDGILKQSA
NEKAFPFWLWIEGILDVIK-RHLLSLWNDGSIMGFISKEREKALLSDKC--PGTFLL---
-----RFSESSKEGAITF---TWVEHDI--HCECSASHNPVGLRTRLPWLLSAQKEKWLN
VKGVPAHSLTDKPVFHSVEPYTKKELSAVSLPDIIRTYKVMAAENIPENPLRFLYPD---
---IPKDKAFGKYYPKPSEPLELMDVENADN-SGYIKTELISVS----------------
------------------------------------------------------------
--------------------------------------EVHPSKLQDNM----------M
PMSPD--------------------------------DYNALRQLVTPVDMAAVDDHVID
G-------------------------FEAFEAQMNE------------
>gi|34334137|gb|AAQ64662.1|	Aedes albopictus
------------------------------------------------------------
-------------MSLW------------------ARVNQLPQPVLEQIRYIYGN-SFPI
EVRHYLAEWIED--RLLNVPVYQHE-------------------------------QDSA
YEQEAATFLNQL----------INELERTAINL------------PEDNV----------
TGRIRLNESARNFRQ--LF-SHNPVQLYSHLINCLQRERQCIAY----------------
-----------PEECVN-----VQDPEIAEVINGLQQLQMLVRA--NENDN-------RN
LVKDYEHLLLEIHEIT-KNKAQMEAIDN---------AQLREHARAALAQQERNVNETVT
LITGKRLNLVDNFRKTIQLTSQVQEKV--LHKYLTQWKINQGFAGNGASG-MSASNLDTI
QAWCENLAEIIWNTKDQIRLAMKNKSK----LNIEEPNLPDFLPQSLVEVTNLLKSLITT
TFIIEKQP--------PQVMKTNTRFAATVRLLIGNT--LNIRMSNPLVRVSIIS-----
---EAQAQATQ----QSNKASEQS-----CGEIMNNTGNLEYNET-TKQLSVSFRNMQLK
KIK-----------RAEKKGTESVMDEKFALLFQSSF--AV----GHGDLVFSVWTISLP
VVVIVHGNQEPQSWATITWDNAFADINRVP--FHVPDKVSWNLLAEALNTKFR----A--
-----STGRSMTPENMHFLCEKAFRASLQ--YPVSNDLAITWSQFCKEPLP---------
-DRTFTFWEWFYAAMKVTR-EHLRGPWNDGSIVGFIHKSKAEDYLLKCP--RGTFLL---
-----RFSDSEL-GGITI---AWVNESN--D-----------------------------
----------GQPQILHIQPFTAKDFATRSLSDRIRDF----------EDLFYLYPN---
---KPKNEAFDRYTTPPGQPRNR---------NYI-PSEVRAVLMPSNNNPISYPNTPNS
YGHLQSPDASRDTPTSGITDVTYRSDMTRPAYLPEARYGMGHSYASASYAGSNI------
---------------------SSPAHSETSPMGPPTQEFPSPGSVGSPPPQMLPACVEQF
NAGAGSPASQTTGGTTLPAELLQPGATGSLTLRTSASEQIIQGLMDHLLS-DYQGQELDD
VSMAQLNANNFYTTTTSSAVPGPQSSGGETAVSGPCSSPPMANGI---
>gi|18958540|gb|AAL82637.1|AF48	Mus musculus
------------------------------------------------------------
-------------MSLW------------------GLISKMSPEKLQRLYV-----DFPQ
RLRHLLADWLES--QPWEFLVG--S--------------------------------DAF
CYNMASALLSAT----------VQRLQATAGEQ------------GKGNS----------
ILPH-----ISTLES--IY-QRDPLKLVATIRQILQGEKKAVIE----------------
----------------------EFRHLPGPFHRKQEELK-------FTTAL-------GR
LQHRVRETRLLRESLQ-------------------------QGAKTGQVSLQNLIDPPVN
G-PGPSEDLATMLQGTVGDLEATQALV--L-KRIQIWKRQQQLAGNGTP---FEESLAGL
QERCESLVEIYSQLQQEI-------------GAASGELEPKTRASLISRLDEVLRTLVTI
SFLVEKQP--------PQVLKTQTKFQAGVRFLLGLQF-LGTSAKPPMVRADMVT-----
---EKQARELS----LAQGPGTGVES---TGEIMNNTVPLENSIP-SNCCSALFKNLLLK
KIK-----------RCERKGTESVTEEKCAVLFSTSF--TL----GPNKLLIQLQALSLP
LVVIVHGNQDNNAKATILWDNAFSEMDRVP--FVVAERVPWEKMCETLNLKFMA--EV--
-----GTSRGLLPEHFLFLAQKIFNDNSL-SVEAFQHRCVSWSQFNKEILL---------
-GRGFTFWQWFDGVLDLTK-RCLRSYWSDRLIIGFISKQYVTSLLLNEP--DGTFLL---
-----RFSDSEI-GGITI---AHVIRGQ--D-----------------------------
----------GSSQIENIQPFSAKDLSIRSLGDRIRDL----------AQLKNLYPK---
---KPKDEAFRSHYKPEQMGKDG---------RGYVSTTIKMTVERDQPLPTPEPQMPAM
VPPYDLGMAPDASM--QLSSDM---GYPPQ--SIHSFQSL--EESMSVLPSFQEPHLQMP
PNMSQITMPFDQPHPQGLLQCQSQEHAVSSP--EPM---LCS-DVTMVEDSCLTQPVGGF
PQGTWVSEDMYPPLMPPT-------------------EQDLTKLLLENQG-EAGG-SLGS
Q------------------PLLQPSPYGQSGISLSHLDLRTNPSW---
>gi|109097352|ref|XP_001115590.	Macaca mulatta
------------------------------------------------------------
-------------MSLW------------------GLVSKMPPEKVQRLYV-----DFPQ
HLRHLLGDWLES--QPWEFLVG--S--------------------------------DAF
CCNMASALLSDT----------VQRLQASAGEQ------------GEGST----------
ILQH-----INTLES--IY-QRDPLKLVATFRQILQGEKKAVME----------------
----------------------QFRHLPMPFHWKQEELK-------FKTAL-------RR
LQHRVGEIHLLREALQ-------------------------KGADAGQVSLHSLIETPAN
G-TGPSEALALLLQETTGELETAKALV--L-KRIQIWKRQQQLAGNGAP---FEESLAPL
QERCESLVDIYSQLQQEV-------------GAAGGELEPKTRASLIGRLDEVLRTLVTS
CFLVEKQP--------PQVLKTQTKFQAGVRFLLGLRF-LGAPAKPPLVRADMVT-----
---EKQARELS----VPQGPGAGAES---TGEIINNTVPLENSIP-GNCCSALFKNLLLK
KIK-----------RCERKGTESVTEEKCAVLFSASF--TL----GPGKLPIQLQALSLP
LVVIVHGNQDNNAKATILWDNAFSEMDRVP--FVVAERVPWEKMCETLNLKFMA--EV--
-----GTNRGLLPEHFLFLAQKIFNDNSL-SMEAFQHRSVSWSQFNKEILL---------
-GRGFTFWQWFDGVLDLTK-RCLRSYWSDRLIIGFISKQYVTSLLLNEP--DGTFLL---
-----RFSDSEI-GGITI---AHVIRGQ--D-----------------------------
----------GSPQIENIQPFSAKDLSIRSLGDRIRDL----------AQLKNLYPK---
---KPKDEAFRSHYKPEQMGKDG---------RGYVPATIKMTVERDQPLPTPELQMPTM
VPSYDLGMAPDSSMSMQLGPDMVPQVYPPHSHSIPPYQGLSPEESVNVLSAFQEPHLQMP
PSLGQMSLSFDQPHPQGLLPCQPQEHAVSSP--DPL---LCS-DVTMVEDSCLSQPVRAF
SQGTWIGEDIFPPLLPPT-------------------EQDLTKLLLEGQG-ESGGGSLGA
Q------------------PLLQPSHYGQPGISMSHMDLRANPSW---
>gi|45553429|ref|NP_996243.1|	Drosophila melanogaster
------------------------------------------------------------
-------------MSLW------------------KRISS-HVDCEQRMAAYYEE-KGML
ELRLCLAPWIED--RIMSEQI------------------------------------TPN
TTDQLERVALKF----------NEDLQQKLLSTRT----------ASDQ-----------
ALKFRVVELCALIQR--IS----AVELYTHLRSGLQKELQLVTEKSVAATAGQSMPLNPY
NMNNTPMVT--GYMVDPSDLLAVSNSCNPPVVQGIGPIHNVQNTGIASPAL-------GM
VTPKVELYEVQHQ--------IMQSLNEFGNCANALKLLAQNYSYMLNSTSSPNAEAAYR
SLIDEKAAIVLTMRRSFMYYESLHEMV--IH-ELKNWRHQQAQAGNGAP--FNEGSLDDI
QRCFEMLESFIAHMLAAVKELMRVR------LVTEEP----ELTHLLEQVQNAQKNLVCS
AFIVDKQP--------PQVMKTNTRFAASVRWLIGSQ--LGIHNNPPTVECIIMS-----
---EIQSQRFVTRNTQMDNSSLSGQS---SGEIQNASSTMEYQQN-NHVFSASFRNMQLK
KIK-----------RAEKKGTESVMDEKFALFFYTTT--TV------NDFQIRVWTLSLP
VVVIVHGNQEPQSWATITWDNAFAEIVRDP--FMITDRVTWAQLSVALNIKFG----S--
-----CTGRSLTIDNLDFLYEKLQREERS--------EYITWNQFCKEPMP---------
-DRSFTFWEWFFAIMKLTK-DHMLGMWKAGCIMGFINKTKAQTDLLRSVYGIGTFLL---
-----RFSDSEL-GGVTI---AYVNENG--------------------------------
-------------LVTMLAPWTARDFQVLNLADRIRDL----------DVLCWLHPSDRN
ASPVKRDVAFGEFYSKRQEPEPLVLDPV----TGYVKSTLHVHV----------------
------------------------------------------------------------
--------------------CRNGENGSTSG--TPH---HAQ-ESMQLG-----------
-----------------NGDF----------------GMAD-FDTITNFE-NF-------
------------------------------------------------
>gi|119929886|ref|XP_001256224.	Bos taurus
------------------------------------------------------------
----VSMMHKSKEMADWKYFVTCGFLMQCEPNVKIWEGKSSQGEI--EVLVAVPE-ASEW
KLRHRLEERKEW--NTYDRCPM--ELVRCIRHILYNEQRLVREANNGSSSAGILVDAMSQ
KHLQINQTFEELRLVTQDTENELKKLQQTQEYF-IIQYQESLRIQGEPGVGGQCMSGGPD
MKQNKVMFALGFFQN--TY-DRCPMELVRCIRHILYNEQRLVRE----------------
--AN--NGT--SPAGSLAD---AMSQKHLQINQTFEELRLVTQD--TENEL-------KK
LQQTQEYFIIQYQESL-RIQAQFAQLAQ-LNPQE--RLSRETALQQKQVSLEAWLQREAQ
TLQQYRVELAEKHQKTLQLLRKQQTII--LDDELIQWKRRQQLAGNGGP---PEGSLDVL
QSWCEKLAEIIWQNRQQIRRAEHLCQQ----LPIPGP-VEEMLAEVNATITDIISALVTS
TFIIEKQP--------PQVLKTQTKFAATVRLLVGGK--LNVHMNPPQVKATIIS-----
---EQQAKSLL----KNENTR--NDY---SGEILNNCCVMEYHQA-TGTLSAHFRNMSLK
RIK-----------RSDRRGAESVTEEKFTILFESQF--SV----GGNELVFQVKTLSLP
VVVIVHGSQDNNATATVLWDNAFAEPGRVP--FAVPDKVLWPQLCEALNMKFKA--EV--
-----QSNRGLTKENLVFLAQKLFNSSSS-HLEDYNGMSVSWSQFNRENLP---------
-GRNYTFWQWFDGVMEVLK-KHLKPHWNDGAILGFVNKQQAHDLLINKP--DGTFLL---
-----RFSDSEI-GGITI---AWKFDSQ--------------------------------
-----------ERMFWNLMPFTTRDFSIRSLADRLGDL----------SYLIYVFPD---
---RPKDEVYSKYYTPVPCEPATAKAV-----DGYVKPQIKQVV----------PEFVSA
S------------------------ADSAG------------------------------
---------------------GSATYMDQAP--SPA---VCP-QPHYNM----------Y
PQNPD-------PVLDNDGDF----------------DLDDTIDVARRVE-ELLGRPMDS
Q----------------------------WIPHAQS------------
>gi|4885615|ref|NP_005410.1|	Homo sapiens
------------------------------------------------------------
-------------MAQW------------------EMLQNLDSPFQDQLHQLYSHSLLPV
DIRQYLAVWIED--QNWQEAAL------------------------------------GS
DDSKATMLFFHF----------LDQLNYECGRCSQ----------DPESL----------
LLQHNLRKFCRDIQ---PF-SQDPTQLAEMIFNLLLEEKRILIQ----------------
--AQRAQLE--QGEPVLET---PVESQQHEIESRILDLRAMMEK--LVKSI-------SQ
LKDQQDVFCFRYKIQA-K--------------------GKTPSLDPHQTKEQKILQETLN
ELDKRRKEVLDASKALLGRLTTLIELL--L-PKLEEWKAQQQKACIRAP---IDHGLEQL
ETWFTAGAKLLFHLRQLLKELKGLSCL----VSYQDDPLTKGVDLRNAQVTELLQRLLHR
AFVVETQPCMPQTPHRPLILKTGSKFTVRTRLLVRLQE-GNESLT---VEVSIDR-----
---NPPQL-------QGFRK---------FNILTSNQKTLTPEKGQSQGLIWDFGYLTLV
EQRSGG------SGKGSNKGPLGVTEELHIISFTVKY--TY------QGLKQELKTDTLP
VVIISNMNQLSIAWASVLWFNLLSPNLQNQQFFSNPPKAPWSLLGPALSWQFS----S--
-----YVGRGLNSDQLSMLRNKLFGQNCR-----TEDPLLSWADFTKRESP---------
-PGKLPFWTWLDKILELVH-DHLKDLWNDGRIMGFVSRSQERRLLKKTM--SGTFLL---
-----RFSESSE-GGITC---SWVEHQD--------------------------------
---------DDKVLIYSVQPYTKEVLQSLPLTEIIRHYQLLTEENIPENPLRFLYPR---
---IPRDEAFGCYYQEKVNLQER---------RKYLKHRLIVVSNRQVDELQQPLELKPE
PELESLELELGLVPEPELSLDLEPLLKAGLDLGPEL------------------------
---------------------ESVLESTLEPVIEPT---LC--MVSQTVPEPDQGPVSQP
VPEPDLPCDLRHLNTEPMEIFR---------------NCVKIEEIMPNGD-PLLAGQNTV
D------------------EVYVSRPSHFYTDGPLMPSDF--------
>gi|15824608|gb|AAL09418.1|AF30	Tetraodon fluviatilis
------------------------------------------------------------
-------------MTQW-----------------LHMSHMLPFLPDQTINNLYPPTTFPI
EVRHFLAEWIES--QRWEDFTL--E--------------------------------NVE
QESQARVLFDQA----------ISTLQTIAQ--------------QNSSV----------
VDRMKLMQISKKLAV-----CHQPLEFAVMVKNILRNENAMINM----------------
------QAQ--TPNIQHC----TPPEVSSPSMQDVDHLVLKVLD--IQNTR-------QT
MHQLQEELNWEKHNCE-AFQ----------GPHQHNGLDKTMAEIQKVQSKIQQLDFNLN
SMAKKRFQL---LKECVDCLDQCQSRF--ISR-LKLWRWEQHKATIGHP---FDDNLNPL
QTWCEQLLGVNGKLRQEL-------------MLIGEP-----IPELQERLRQLLQVLIQS
SLVVEKQP--------PQVIKTQSKFSTTVRYLLGEK---IAPGKPVVLKAQIIN-----
---ESQARN------QGSIP---GDT---VGELLNNTAILEHNTA-SKNTCATFRNMSIK
KIK-----------RADRKGTESVTEEKFALFFSTEI--TI----TGCDTPYRIQMISLP
LVVIVHGSQDNNALATIIWDCAFCEPDRVP--FVVPEYVPWRMMYSTLNSKFTS--EV--
-----QTKHHLDKCNQHFLAQKIFDKPDY--NGDFSNMMVSWAQFNKEVLP---------
-GRMFTFWQWFEGAMELTK-KHLKTYWSEKLIFGFIGKQHLHLILKDKP--NGTFLL---
-----RFSDSEI-GGITI---AYVSTTD--N-----------------------------
----------GGLKIQNIQPFAKRDLEIRSLGDRIRDI----------SEITHLYPN---
---RPKHDVFQKFYTEPQASPI----------GGYIPVSLHTKV---GTEAASTSHLSPS
TV----------------------CPSPSM------------------------------
-----------------AEVCPSPSMAGVCP--SPSMAGVCP-SPSMTVVSENSSSALGY
PLNQFPQQQCDQPEAIPPD------------------IMDVVASPEGFLP-ELSTGNNMD
L------------------DIESLLQVNTWREADIYASDM--------
>gi|57164401|ref|NP_001009402.1	Ovis aries
------------------------------------------------------------
-------------MAGW------------------IQAQQLQGDALRQMQVLYGQ-HFPI
EVRHYLAQWIES--QPWDAIDL--D--------------------------------NPQ
DRAQVTQLLEGL----------VQELQKKAEHQ-V----------GEDGF----------
LLKIKLGHYVHVSSR--TRTTAAPWSWLRCIRHILYNEQRLVRE----------------
--AT--NGN--SSAGILVD---AMSQKHLQINQTFEELRLVTQD--TENEL-------KK
LQQTQEYFIIQYQESL-RIQAQFAQLAQ-LNPQE--RLSRETALQQKQVSLEAWLQREAQ
TLQQYRVELAEKHQKTLQLLRKQQTII--LDDELIQWKRRHDWRGMEAP---PR-SLDVL
QSWCEKLAEIIWQNRQQIRRAEHLCQQ----LPIPGP-VEEMLAEVNATITDIISALVTS
TFIIEKQP--------PQVLKTQTKFAATVRLLVGGK--LNVHMNPPQVKATIIS-----
---EQQAKSLL----KNENTR--NEC---SGEILNNCCVMEYHQR-TGTLSAHFRNMSLK
RIK-----------RADRRGAESVTEEKFTVLFESQF--SV----GSNELVFQVKTLSLP
VVVIVHGSQDHNATATVLWDNAFAEPGRVP--FAVPDKVLWPQLCEALNMKFKA--EV--
-----QSNRGLTKENLLFLAQKLFNNSSS-HLEDYNGMSVSWSQFNRENLP---------
-GWNYTFWQWFDGVMEVLK-KHHKPHWNDGAILGFVNKQQAHDLLINKP--DGTFLL---
-----RFSDSEI-GGITI---AWKFDSP--------------------------------
-----------DRNLWNLKPFTTREGSIRSLADRLGDL----------NYLIYVFPD---
---RPKDEVFSKYYTPVLAKAV----------DGYVKPQIKQVV----------PEFVSA
S------------------------ADSAG------------------------------
---------------------SSATYMDQAP--SPA---VCP-QPHYNM----------Y
PQNPD-------PVLDQDGEF----------------DLDETMDVARHVE-ELLRRPNGQ
S------------------GPLSPPPAGLFTPARGSLS----------
>gi|108874199|gb|EAT38424.1|	Aedes aegypti
------------------------------------------------------------
-------------MSLW------------------ARVNQLPQPVLEQIRYIYGN-SFPI
EVRHYLAEWIEE--RLLNVPVYQHE-------------------------------QDSA
YEQEAATFLNQL----------INELERTAINL------------PEDNV----------
TGRIRLNESARNFRQ--LF-SHNPVQLYSHLINCLQRERQCIAY----------------
-----------PEECVN-----VQDPEIAEVINGLQQLQMLVRA--NENDN-------RN
LVKDYEHLLLEIHEIT-KNKAQMEAIDN---------AQLREHARAALVQQERNVNETVT
LITGKRLNLVDNFRKTIQLTSQVQEKV--LHKYLTQWKINQGFAGNGASG-MSASNLDTI
QAWCENLAEIIWNTKDQIRLAMKNKSK----LNIEEPNLPDFLPQSLVEVTNLLKALITT
TFIIEKQP--------PQVMKTNTRFAATVRLLIGNT--LNIRMSNPLVRVSIIS-----
---EAQAQATQ----QSNKASEQS-----CGEIMNNTGNLEYNET-TKQLSVSFRNMQLK
KIK-----------RAEKKGTESVMDEKFALLFQSSF--AV----GHGDLVFSVWTISLP
VVVIVHGNQEPQSWATITWDNAFADINRVP--FHVPDKVSWNLLAEALNTKFR----A--
-----STGRSMTPENMHFLCEKAFRANLQ--YPVSNDLTITWSQFCKEPLP---------
-DRTFTFWEWFYAAMKVTR-EHLRGPWNDGSIVGFIHKSKAEDYLLKCS--RGTFLL---
-----RFSDSEL-GGITI---AWVNESN--D-----------------------------
----------GQPQILHIQPFTAKDFATRSLSDRIRDF----------EDLFYLYPN---
---KPKNEAFDRYTTPPGQPRNR---------NYI-PSEVRAVLMPSNNNPISYPN----
------------------------------------------------------------
---------------------TPNSYGHLQ---SPDASRDTPTSGSYNL-----------
-------------------------------------ENDQVNHLPYQ---PLADLELEN
I--------------------------DMFASSYT-------------
>gi|73965784|ref|XP_859906.1|	Canis familiaris
------------------------------------------------------------
-------------MAGW------------------IQAQQLQGDALRQMQVLYGQ-HFPI
EVRHYLAQWIES--QPWDAIDL--D--------------------------------NPQ
DRAQATQLLEGL----------VQELQKKAEHQ-V----------GEDGF----------
LLKIKLGHYASQLQN--TY-DGCPMELVRCIRHILYNEQRLVRE----------------
--AN--NGN--SPAGILVD---AMSQKHLQINQTFEELRLVTQD--TENEL-------KK
LQQTQEYFIIQYQESL-RIQAQFSQLAQ-LNPQE--RLSRETALQQKQVSLEAWLQREAQ
TLQQYRVELAEKHQKTLQLLRKQQTII--LDDELIQWKRRQQLAGNGGP---PEGSLDVL
QSWCEKLAEIIWQNRQQIRRAEHLCQQ----LPIPGP-VEEMLAEVNATITDIISALVTS
TFIIEKQP--------PQVLKTQTKFAATVRLLVGGK--LNVHMNPPQVKATIIS-----
---EQQAKSLL----KNENAR--NEC---SGEILNNCCVMEYHQA-TCTLSAHFRNMSLK
RIK-----------RADRRGAESVTEEKFTVLFESQF--SV----GSNELVFQVKTLSLP
VVVIVHGSQDHNATATVLWDNAFAEPGRVP--FAVPDKVLWPQLCEALNMKFKA--EV--
-----QSNRGLTKENLVFLAQKLFNSSSS-HLEDYNGMSVSWSQFNRENLP---------
-GWNYTFWQWFDGVMEVLK-KHHKPHWNDGAILGFVNKQQAHDLLINKP--DGTFLL---
-----RFSDSEI-GGITI---AWKFDSP--------------------------------
-----------DRNLWNLKPFTTRDFSIRSLADRLGDL----------NYLIYVFPD---
---RPKDEVFSKYYTPVPRPSAAKAV------DGYVKPQIKQVV----------PEFVSA
S------------------------TDSAG------------------------------
---------------------ASATYMDQAP--SPA---VCP-QAHYNM----------Y
PQNPD-------SVLDQDGEF----------------DLDETMDVARHVE-ELLRRPMDS
L------------------DPRLSPPAGLFTAARGSLS----------
