>gi|45198718|ref|NP_985747.1|	Ashbya gossypii
---------------------MDKKIKRFLKDAVRVAPKISNKGELF--------ELKNG
LVSKYPQTRKDAIKKTIQQMTLGKDVSSLFPDVLKNIATSDIEQKKLVYLYVINYAQTHP
ELCILAVNTFVTDAQDPNPLIRCMAIRTMSMIRVDKILEHVEIPLRKTLQDDNPYVRKTA
VICVAKLFQLNRELCMELDVLTDLMSALDDSNPM--------------------------
VVANSIAALTEIYELD---------------------RSAV-PLPLLIQSHVTQFLNALN
ECTEWARITILGALAQY----------EAKDAMEAQDTI-------VRVTPHLQ-HVTAA
VVLASVKVIV--KNLDFL-PREMQ--KQPSEKIST----ALVSLMSTP-PEMQYVALKTI
RILLQKY-----------PTLLEKELRIFYVKFNDPMYVKLEKLDIMVRLVTTSNLKQCS
TLLLELREYALEFEPEFVSKAILAISQLAIKF--AHGADAVNASKFIAKAIDILSTLIQD
R-N-TFQDECLISICDLLRYDP-------QLSGMPLSIISSWTDAESRLVTDQGKCNYIW
LLGQY--QFPN-AEEKLMQFVDTYPQQGQS---------------------TQMSILVTV
VKLSQQLP----------GHVLQRVLELATTQAQDIDIRDMAMLYWRCLSLPNP-----E
SLINE--LC-NTKLPQLTNTLDYFSPE--LLHTLLNELSTLSSIYYKPLSQF--------
----KYRAPQQ--------SEVQSKALDELTSLAHAEIAK-----------NMNNETLLN
MDDAQ-------------------------------------------------------
-----------------------------------AAPKPGNTLAELSDLFGNTGG----
------------------------------------------------------------
---------SLLDKPMQDM--------------SLHADSRT-------------------
-----V------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
----------------------QGASKDLLDLF
>gi|149724036|ref|XP_001503980.	Equus caballus
-----------------------MTDSKY----FTTNKK----GEIF--------ELKAE
LNNEKKEKRKEAVKKVIAAMTVGKDVSSLFPDVVNCMQTDNLELKKLVYLYLMNYAKSQP
DMAIMAVNSFVKDCEDPNPLIRALAVRTMGCIRVDKITEYLCEPLRKCLKDEDPYVRKTA
AVCVAKLHDINAQMVEDQGFLDSLRDLIADSNPM--------------------------
VVANAVAALSEISESH---------------------PNSN--LLDLNPQNINKLLTALN
ECTEWGQIFILDCLSNY----------NPKDDREAQSIC-------ERVTPRLS-HANSA
VVLSAVKVLM--KFLELL-PKDSDYYNMLLKKLAP----PLVTLLSGE-PEVQYVALRNI
NLIVQKR-----------PEILKQEIKVFFVKYNDPIYVKLEKLDIMIRLASQANIAQ--
-VLAELKEYATEVDVDFVRKAVRAIGRCAIKV--EQSAE---------RCVSTLLDLIQT
KVN-YVVQEAIVVIRDIFRKYPNKYE---SIIATLCENLDSLDEPD-------ARAAMIW
IVGEYAERIDN-ADELLESFLEGFHDESTQ---------------------VQLTLLTAI
VKLFLKKP-------SETQELVQQVLSLATQDSDNPDLRDRGYIYWRLLS--TD-----P
VTAKE--VV-LSEKPLISEETDLIEPT--LLDELICHIGSLASVYHKPPNAFVE----GS
HGIHRKHLPIHHGS-----TDAGDSP-VGTTTATNLEQPQ-VIPSQ-----GDLLGDLLN
LDLGPPVNVPQV--SSMQMGAV-------DLLGGGLD-SLL-----GSDLGGGIGGS---
------------------------PAVMPATFA--PSPTPAVVSSGLNDLFELSTGIGMA
P------GGYVAPKAV---------------------WLPAVKAKGLEISGTFTHRQGHI
Y-----MEMNFTNKALQHMTDFAIQFNKNSF--GVIPSTPL-------------------
-----AIHTPLMPNQSIDVSLPLNTLGPVMK-----------MEPLNNLQ----------
----------------------VAV-KNNIDVFYFSCLIPLNVLFVEDGKM---------
---ERQVFLATWKDIPNENELQFQIKECH-LNA----DTVSSKLQNNNVYTIAKRNVEGQ
DMLYQ--SLKLTNGIWILAELRIQPGNPNYTDMRLS----------LKC----------R
A-------PEVSQYI-------YQVYDSILKN-
>gi|125815812|ref|XP_686642.2|	Danio rerio
-------MEWASQLCENRGLGSKMTDSKY----FTTTKK----GEIF--------ELKAE
LNSDKKEKKKEAVKKVIASMTVGKDVSALFPDVVNCMQTDNLELKKLVYLYLMNYAKSQP
DMAIMAVNTFVKDCEDPNPLIRALAVRTMGCIRVDKITEYLCEPLRKCLKDEDPYVRKTA
AVCVAKLHDINAQLVEDQGFLDTLKDLISDSNPM--------------------------
VVANAVAALSEIAESH---------------------PNSN--LLDLNPQTINKLLTALN
ECTEWGQIFILDCLANY----------TPRDDRESQSIC-------ERVTPRLS-HANSA
VVLSAVKVLM--KFMEML-PKDLDYYGTLLKKLAP----PLVTLLSAE-PELQYVALRNI
NLIVQKR-----------PEILKHEMKVFFVKYNDPIYVKLEKLDIMIRLASQANIAQ--
-VLAELKEYATEVDVDFVRKAVRAIGRCAIKV--EQSAE---------RCVSTLLDLIQT
KVN-YVVQEAIVVIKDIFRKYPNKYE---SVIATLCENLDSLDEPE-------ARAAMIW
IVGEYAERIDN-ADELLESFLEGFHDESTQ---------------------VQLQLLTAI
VKLFLKKP-------TETQELVQQVLSLATQDSDNPDLRDRGYIYWRLLS--TD-----P
VAAKE--VV-LAEKPLISEETDLIEPT--LLDELICHIGTLASVYHKPPSAFVE----GS
RGVQHKRLPARAGS-----GESAESPEVGQSGTSEA-PPA-VIPSQ-----GDLLGDLLN
LDLAPATTTVPSVQPSMQMGAM-------DLLGGGLD-SLL---------GGDIGGSPSM
GA-------------------ALGAPAAMPA----ALSNAPAVGGGLGDLFDLGGGVGMP
T------GFYVAPKTL---------------------FLPAMKAKGLEISGTFARRGGII
Q-----MDLSLTNKAMSVMTDFAIQFNRNSF--GLAPAGPL-------------------
-----QVLTPLTPNQTIDVSLPLGTTGPVMK-----------MEPLNNLQ----------
----------------------VAV-KNNIDVFYFSCQYPLSLLFVEDGKM---------
---ERQVFLATWKDIPNDNEAQFQIKDVH-LNS----DAASNKLQGSNIFTIAKRTVDAQ
DMLYQ--SIKLTNGIWVLAEMRVQTGNPNYT---LS----------IKC----------R
A-------PEVSQFV-------YQCYELVLKN-
>gi|119600544|gb|EAW80138.1|	Homo sapiens
-----------------------MTDSKY----FTTNKK----GEIF--------ELKAE
LNNEKKEKRKEAVKKVIAAMTVGKDVSSLFPDVVNCMQTDNLELKKLVYLYLMNYAKSQP
DMAIMAVNSFVKDCEDPNPLIRALAVRTMGCIRVDKITEYLCEPLRKCLKDEDPYVRKTA
AVCVAKLHDINAQMVEDQGFLDSLRDLIADSNPM--------------------------
VVANAVAALSEISESH---------------------PNSN--LLDLNPQNINKLLTALN
ECTEWGQIFILDCLSNY----------NPKDDREAQSIC-------ERVTPRLS-HANSA
VVLSAVKVLM--KFLELL-PKDSDYYNMLLKKLAP----PLVTLLSGE-PEVQYVALRNI
NLIVQKR-----------PEILKQEIKVFFVKYNDPIYVKLEKLDIMIRLASQANIAQ--
-VLAELKEYATEVDVDFVRKAVRAIGRCAIK----QSAE---------RCVSTLLDLIQT
KVN-YVVQEAIVVIRDIFRKYPNKYE---SIIATLCENLDSLDEPD-------ARAAMIW
IVGEYAERIDN-ADELLESFLEGFHDESTQ---------------------VQLTLLTAI
VKLFLKKP-------SETQELVQQVLSLATQDSDNPDLRDRGYIYWRLLS--TD-----P
VTAKE--VV-LSEKPLISEETDLIEPT--LLDELICHIGSLASVYHKPPNAFVE----GS
HGIHRKHLPIHHGS-----TDAGDSP-VGTTTATNLEQPQ-VIPSQ-----GDLLGDLLN
LDLGPPVNVPQV--SSMQMGAV-------DLLGGGLD-SLL-----GSDLGGGIGGSPAV
GQ-------------------SFIPSSVPATFA--PSPTPAVVSSGLNDLFELSTGIGMA
P------GGYVAPKAV---------------------WLPAVKAKGLEISGTFTHRQGHI
Y-----MEMNFTNKALQHMTDFAIQFNKNSF--GVIPSTPL-------------------
-----AIHTPLMPNQSIDVSLPLNTLGPVMK-----------MEPLNNLQ----------
----------------------VAV-KNNIDVFYFSCLIPLNVLFVEDGKM---------
---ERQVFLATWKDIPNENELQFQIKECH-LNA----DTVSSKLQNNNVYTIAKRNVEGQ
DMLYQ--SLKLTNGIWILAELRIQPGNPNYT---LS----------LKC----------R
A-------PEVSQYI-------YQVYDSILKN-
>gi|68471507|ref|XP_720060.1|	Candida albicans
--MSSSYKQTINKNFNKVNSILERKLRKY----LVGPKK----GETF--------ELKNG
LVSQYKHERKDAIQRVIQAMTVGKDVSSLFPDVLKNIATYDLEQKKLVYLYLMNYAKTNP
ELCILAVNTFVQDTEDPNPLIRALAIRTMGCIRVAKMVEYLEIPLQRTLADENPYVRKTA
AICVAKLFDLNPEMCVEFGFLDELKKLLSDPNPM--------------------------
VVANAINALSEIRDMN---------------------TNENLEILAFNREVINSLLLCLN
ECTEWGRITILNTLAEY----------DTDNSEEANHIM-------GRVIPQLQ-HVNPS
VVLSSIKAIL--HHLNAI-PVTAQ-RSNILKKLSA----PLVSLVSTSIPEAQYVGLKNI
RIILEKY-----------PNVLSKELRVFFIKYSDPLYLKLEKLEIMIRLASEQNSAL--
-LLGELKEYAMEFEPALVTKAIKSIGSVAIKL--QESAV---------KAINLLHEIIDE
RGGDLIINESVTVLVNILRRYPGKNDLATLIIPVISNHVNELNKTE-------ALSGYIW
LLGEYPKYFSG-LHKKLSDLVDGFLEDDSV---------------------LQLNILSTI
VKINLELSSNGGSGNSQYSNLLQKVLELATKECENADVRDKAYIYWRLLSSSSS-----E
DQQKK--IL-LTKLPPIETTISSFSPG--LLETLLDELSTLSSVYYKPAKSFID------
--------PNAYSR-----VPVEKKNKTKIEDLKNMAKEE-IIT-------NARNDNLLD
FDDDDDEEGDGVSGSNGDSGNV-------GNLLDELN-DLF-------------------
----------------------STPPPPPSSSSQNSQSQIAGGQTSTNDILSLFNTINTT
T------TTTTTPQQS--------------------------------------------
----------TQSSTTHGIENLSVS--------GNASTTTK-------------------
-----N------------------------------------------------------
--------------------------KNNVN-----------------------------
------------------------------------------------------------
------------------------------------------------------------
--------------------------NDLLDLF
>gi|115693323|ref|XP_001187613.	Strongylocentrotus purpuratus
-----------------------MSDSKY----FTTTKK----GEIY--------ELKAD
LNSDKKEKKKEAVKKVIASMTVGKDVSSLFPDVVNCMQTDNLELKKLVYLYLMNYAKSQP
DMAIMAVNTFVKDCEDPNPLIRALAVRTMGCIRVDKITEYLCEPLRKCLKDEDPYVQKTA
AVCVAKLYDINPVLVEDQGFIDLLRDLLTASNPM--------------------------
VVANAVAALSEINDAS---------------------PTGS-TLFELNSQTINKLLTALN
ECTEWGQIFILDSLANF----------SPKDEKEAQSIC-------ERVTPRLA-HANAA
VVLSAVKVLM--KFMELM-PPSGEYVVALTKKLAP----PLVTLLSAE-PEVQYVALRNI
NLIVQKR-----------PDILKEEMKVFFVKYNDPIYVKLEKLDIMIRLASQSNIAQ--
-VLAELKEYATEVDVDFVRKSVRAIGRCAIKV--DVSAE---------RCVSTLLDLIQT
KVN-YVVQEAIVVIKDIFRKYPNKYE---SIIATLCENLDSLDEPE-------ARASMIW
ILGEYAERIDN-AEELLESFVEGFHDENTQ---------------------VQLQLLTSI
VKLFLKRP-------QDTQELVQNVLSLATQECDNPDLRDRGYIYWRLLS--TD-----P
AAAKD--VV-LAEKPLISEETDLIEPT--LLDELICYIGSLASVYHKPPSAFVE-----G
RTATRRFLPTRAPG-----SSGSASPETETAPSSAIPETT-VIPQQQQHSGGDLIGDLLS
IDLGDSGMVQQPPQQQPNMGGM--------GMGMNMG-----------------------
---------------------AFG-----------GAPQPETTGGGAMDLLG--------
-----------------------------------------DNMESLIIHQHILRKANHI
---------------------------------SSPHQTPT-------------------
-----Q------------------------------------------------------
----------------------------------------------DDGTT---------
------------------------------------------------------------
------------------------------------------------------------
----------------------QPYYKRTL---
>gi|50308991|ref|XP_454501.1|	Kluyveromyces lactis
-------------------MGVDKKIKKFLRDAIRVAPKISNKGELF--------ELRNG
LVSQYPQTRKDAIRKIIQQMTSGKDVSSLFPDVLKNIATQDIEQKKLVYLYVANYAETHP
ELCILVVNTFVSDAADPNPLIRSMAIRTMSMIRVDKILEYIEIPLRKTLVDDNPYVRRTA
VLCVAKLFQLNPDLCRELGVLNDLQDALSDDNPM--------------------------
VVANALAALHEINELD---------------------PGSI-DIKKLVSQNVKRFLNVLN
ECTEWARITILESLSEH----------KPIDPMESQEII-------DRVVPHLQ-HVNPS
VVLISVKCIL--IHLPNL----NTVHDSIYNKLST----ALVSLMSTP-VEIQYVALRNI
RIILDAF-----------PNLLRKELRIFYVKFNDPLYVKIEKLDILLRLVPVDNLKHCQ
MLFNELKEYAKDFDHEFVTKAIQSISQLAIKV--SNGGE-DTNNKFLNMVMEEFVSIVQE
RE--EFRDILMRCVCDMLRYDSDNNLIKETSKNELGAIISSWQDIDTIFTSDLGSCNYIW
FITNYTN--EN-LETKLEPLVEVFDELGSL---------------------TQMSLLMGV
VKCHN----------AVSSAFLQKILELCTTDVHDLDVRDMAMMYWRCLSIDNG-----D
QIINQ--LFDKHEIPKLHSTLDHFSKE--TLQSLLQELSTLSSVYFKPISQM--------
---QRRPNEVHI-------IKDKDIDELKGMATNE------IL--------KNMNDDVL-
LDMGDSSATRST--------------------------GVL-------------------
--------------------------------------------DELNDLFDITGDMGKV
N-----------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
---------------------------------------ISQKTNNNNNNTSNSHATDLL
DLM---------------------------------------------------------
---------------------------------
>gi|115497346|ref|NP_001068593.	Bos taurus
-----------------------MTDSKY----FTTNKK----GEIF--------ELKAE
LNNEKKEKRKEAVKKVIAAMTVGKDVSSLFPDVVNCMQTDNLELKKLVYLYLMNYAKSQP
DMAIMAVNSFVKDCEDPNPLIRALAVRTMGCIRVDKITEYLCEPLRKCLKDEDPYVRKTA
AVCVAKLHDINAQMVEDQGFLDSLRDLIADSNPM--------------------------
VVANAVAALSEISESH---------------------PNSN--LLDLNPQNINKLLTALN
ECTEWGQIFILDCLSNY----------NPKDDREAQSIC-------ERVTPRLS-HANSA
VVLSAVKVLM--KFLELL-PKESDYYNMLLKKLAP----PLVTLLSGE-PEVQYVALRNI
NLIVQKR-----------PEILKQEIKVFFVKYNDPIYVKLEKLDIMIRLASQANIAQ--
-VLAELKEYATEVDVDFVRKAVRAIGRCAIKV--EQSAE---------RCVSTLLDLIQT
KVN-YVVQEAIVVIRDIFRKYPNKYE---SIIATLCENLDSLDEPD-------ARAAMIW
IVGEYAERIDN-ADELLESFLEGFHDESTQ---------------------VQLTLLTAI
VKLFLKKP-------SETQELVQQVLSLATQDSDNPDLRDRGYIYWRLLS--TD-----P
VTAKE--VV-LSEKPLISEETDLIEPT--LLDELICHIGSLASVYHKPPNAFVE----GS
HGIHRKHLPIHHGS-----TDAGDSP-VGTTTATNLEQPQ-VIPSQ-----GDLLGDLLN
LDLGPPVNVPQV--SSMQMGAV-------DLLGGGLD-SLL-----GSDLGGGIGGSPAV
GQ-------------------SFIPSSVPATFA--PSPTPAVVSSGLNDLFELSTGIGMA
P------GGYVAPKAV---------------------WLPAVKAKGLEISGTFTHRQGHI
Y-----MEMNFTNKALQHMTDFAIQFNKNSF--GVIPSTPL-------------------
-----AIHTPLMPNQSIDVSLPLNTLGPVMK-----------MEPLNNLQ----------
----------------------VAV-KNNIDVFYFSCLIPLNVLFVEDGKM---------
---ERQVFLATWKDIPNENELQFQIKECH-LNA----DTVSSKLQNNNVYTIAKRNVEGQ
DMLYQ--SLKLTNGIWILAELRIQPGNPNYT---LS----------LKC----------R
A-------PEVSQYI-------YQVYDSILKN-
>gi|26329729|dbj|BAC28603.1|	Mus musculus
-----------------------MTDSKY----FTTTKK----GEIF--------ELKAE
LNSDKKEKKKEAVKKVIASMTVGKDVSALFPDVVNCMQTDNLELKKLVYLYLMNYAKSQP
DMAIMAVNTFVKDCEDPNPLIRALAVRTMGCIRVDKITEYLCEPLRKCLKDEDPYVRKTA
AVCVAKLHDINAQLVEDQGFLDTLKDLISDSNPM--------------------------
VVANAVAALSEIAESH---------------------PSSN--LLDLNPQSINKLLTALN
ECTEWGQIFILDCLANY----------MPKDDREAQSIC-------ERVTPRLS-HANSA
VVLSAVKVLM--KFMEML-SKDLDYYATLLKKLAP----PLVTLLSAE-PELQYVALRNI
NLIVQKR-----------PEILKHEMKVFFVKYNDPIYVKLEKLDIMIRLASQANIAQ--
-VLAELKEYATEVDVDFVRKAVRAIGRCAIKV--EQSAE---------RCVSTLLDLIQT
KVN-YVVQEAIVVIKDIFRKYPNKYE---SVIATLCENLDSLDEPE-------ARAAMIW
IVGEYAERIDN-ADELLESFLEGFHDESTQ---------------------VQLQLLTAI
VKLFLKKP-------TETQELVQQVLSLATQDSDNPDLRDRGYIYWRLLS--TD-----P
VAAKE--VV-LAEKPLISEETDLIEPT--LLDELICYIGTLASVYHKPPNAFVE----GG
RGVVHKSLPPRTAS-----SESTESPETAPAGAPAGDQPD-VIPAQ-----GDLLGDLLN
LDLGPPVSGPPLAASSVQMGAV-------DLLGGGLD-SLM------GDESEGIGDS---
---------------------NFGAPSASVAAAPAPARLGAPISSGLSDLFDLTSGVGTL
S------GSYVAPKAV---------------------WLPAMKAKGLEISGTFTRQAGSI
S-----MDLQLTNKALQVMTDFAIQFNRNSF--GLAPAAPL-------------------
-----QVHVPLSPNQTVEISLPLNTVGSVLK-----------MEPLNNLQ----------
----------------------VAV-KNNIDVFYFSTLYPLHVLFVEDGKM---------
---DRQMFLATWKDIANENEAQFQIRDCP-LNT----EAASNKLQSSNIFTVAKRNVEGQ
DMLYQ--SLKLTNGIWVLAELRIQPGNPSFTDLELS----------LKC----------R
A-------PEVSQHV-------YQAYETILKN-
>gi|17647183|ref|NP_523415.1|	Drosophila melanogaster
-----------------------MTDSKY----FTTTKK----GEIF--------ELKSE
LNNDKKEKKKEAVKKVIASMTVGKDVSALFPDVVNCMQTDNLELKKLVYLYLMNYAKSQP
DMAIMAVNTFVKDCEDSNPLIRALAVRTMGCIRVDKITEYLCEPLRKCLKDEDPYVRKTA
AVCVAKLYDISATMVEDQGFLDQLKDLLSDSNPM--------------------------
VVANAVAALSEINEAS---------------------QSGQ-PLVEMNSVTINKLLTALN
ECTEWGQVFILDSLANY----------SPKDEREAQSIC-------ERITPRLA-HANAA
VVLSAVKVLM--KLLEML-SSDSDFCATLTKKLAP----PLVTLLSSE-PEVQYVALRNI
NLIVQKR-----------PDILKHEMKVFFVKYNDPIYVKLEKLDIMIRLANQSNIAQ--
-VLSELKEYATEVDVDFVRKAVRAIGRCAIKV--EPSAE---------RCVSTLLDLIQT
KVN-YVVQEAIVVIKDIFRKYPNKYE---SIISTLCENLDTLDEPE-------ARASMVW
IIGEYAERIDN-ADELLDSFLEGFQDENAQ---------------------VQLQLLTAV
VKLFLKRP-------SDTQELVQHVLSLATQDSDNPDLRDRGFIYWRLLS--TD-----P
AAAKE--VV-LADKPLISEETDLLEPT--LLDELICHISSLASVYHKPPTAFVE----GR
GAGVRKSLPNRAAG-----SAAGAEQAENAAGSEAM-----VIPNQ-----ESLIGDLLS
MDINAPAMPS----APAATSNV-------DLLGGGLD-ILL-------------------
----------------------GGPP---------AEAAPGGATSLLGDIFGLGGATLS-
-------VGVQIPKVT---------------------WLPAEKGKGLEIQGTFSRRNGEV
F-----MDMTLTNKAMQPMTNFAIQLNKNSF--GLVPASPM-------------------
-----Q-AAPLPPNQSIEVSMALGTNGPIQR-----------MEPLNNLQ----------
----------------------VAV-KNNIDIFYFACLVHGNVLFAEDGQL---------
---DKRVFLNTWKEIPAANELQYTLSGVI-GTT----DGIASKMTTNNIFTIAKRNVEGQ
DMLYQ--SLKLTNNIWVLLELKLQPGNPEAT---LS----------LKS----------R
S-------VEVANII-------FAAYEAIIRSP
>gi|156544522|ref|XP_001607195.	Nasonia vitripennis
-----------------------MTDSKY----FTTTKK----GEIF--------ELKSE
LNNDKKEKKKEAVKKVIASMTVGKDVSALFPDVVNCMQTDNLELKKLVYLYLMNYAKSQP
DMAIMAVNTFVKDCEDPNPLIRALAVRTMGCIRVDKITEYLCEPLRKCLKDEDPYVRKTA
AVCVAKLYDINAGLVEDQGFLDQLKDLLSDSNPM--------------------------
VVANAVAALSEINESS---------------------PSGQ-PLVEMNAQTINKLLTALN
ECTEWGQVFILDSLANY----------SPKDDREAQSIC-------ERITPRLA-HANAA
VVLSAVKVLM--KLMEML-QSESDFVGTLTKKLAP----PLVTLLSSE-PEVQYVALRNI
NLIVQKR-----------PDILKHEMKVFFVKYNDPIYVKLEKLDIMIRLASQANIAQ--
-VLSELKEYATEVDVDFVRKAVRAIGRCAIKV--EPSAE---------RCVSTLLDLIQT
KVN-YVVQEAIVVIKDIFRKYPNKYE---SIISTLCENLDTLDEPE-------ARASMIW
IIGEYAERIDN-ADELLESFLEGFHDENTQ---------------------VQLQLLTAI
VKLFLKRP-------TDTQELVQQVLSLATQDSDNPDLRDRGFIYWRLLS--TD-----P
AAAKE--VV-LAEKPLISEETDLLEPT--LLDELICHISSLASVYHKPPTAFVE----GR
AAGARKSLPAR--------SNSNDDPASRSQPQAQ------VIPAQ-----DSLIGDLLS
MDIGGPSLVTPTPPPSTGLGL--------DLLSSGLD-GIL-------------------
----------------------GGPETTA------PPAVSQTTTGLLGDIFGFTQGT---
-------TSYVAPKVN---------------------WLPAEKGKGFDIWGTFSRKNGQI
N-----MDMTFTNKAMQPMGGFAIQLNKNSF--GLAPAVPL-------------------
-----QVPAPLNPGQSIEASVVLSTVGAVQR-----------MEPLNNLQ----------
----------------------VAI-KNNIDVFYFACIVPMNVYFTEDGQL---------
---DKRVFLSTWKDIPAQNEVQYTLSGIM-LTT----DQVVSKMQQNNVFTIAKRNVEGQ
DMLYQ--SLKLTNNVWVLVELKIQPGNPDIL---LS----------LKS----------R
T-------VEVASAI-------FQAYNAILYS-
>gi|109093772|ref|XP_001105615.	Macaca mulatta
-----------------------MTDSKY----FTTTKK----GEIF--------ELKAE
LNSDKKEKKKEAVKKVIASMTVGKDVSALFPDVVNCMQTDNLELKKLVYLYLMNYAKSQP
DMAIMAVNTFVKDCEDPNPLIRALAVRTMGCIRVDKITEYLCEPLRKCLKDEDPYVRKTA
AVCVAKLHDINAQLVEDQGFLDTLKDLISDSNPM--------------------------
VVANAVAALSEIAESH---------------------PSSN--LLDLNPQSINKLLTALN
ECTEWGQIFILDCLANY----------TPKDDREAQSIC-------ERVTPRLS-HANSA
VVLSAVKVLM--KFMEML-SKDLDYYGTLLKKLAP----PLVTLLSAE-PELQYVALRNI
NLIVQKR-----------PEILKHEMKVFFVKYNDPIYVKLEKLDIMIRLASQANIAQ--
-VLAELKEYATEVDVDFVRKAVRAIGRCAIKV--EQSAE---------RCVSTLLDLIQT
KVN-YVVQEAIVVIKDIFRKYPNKYE---SVIATLCENLDSLDEPE-------ARAAMIW
IVGEYAERIDN-ADELLESFLEGFHDESTQ---------------------VQLQLLTGI
VKLFMKKP-------TETQELVQQVLSLATQDSDNPDLRDRGYIYWRLLS--TD-----P
VAAKE--VV-LAEKPLISEETDLIEPT--LLDELICYIGTLASVYHKPPSAFVE----GG
RGVVHKSLPPRTAS-----SESAESPETAPAGAPPGEQPD-VIPAQ-----GDLLGDLLN
LDLGPPVSGPPLTTSSVQMGAV-------DLLGGGLD-SLM------GDEPEGIGGT---
---------------------NFVAPPTAAV----PASLGAPIGSGLSDLFDLTSGVGTL
S------GSYVAPKAV---------------------WLPAMKAKGLEISGTFTRQVGSI
S-----MDLQLTNKALQVMTDFAIQFNRNSF--GLAPAAPL-------------------
-----QVHAPLSPNQTVEISLPLSTVGSVMK-----------MEPLNNLQ----------
----------------------VAV-KNNIDVFYFSTLYPLHILFVEDGKM---------
---DRQMFLATWKDIPNENEAQFQIRDCP-LNA----EAVSSKLQSSNIFTVAKRNVEGQ
DMLYQ--SLKLTNGIWVLAELRIQPGNPSCTVRAPAPTLWPWSLPFVPCQGVVLVEDAVQ
ASLQAWLEPESVRSLKRTFLESFHIHPVRLPR-
>gi|45361257|ref|NP_989206.1|	Xenopus tropicalis
-----------------------MTDSKY----FTTNKK----GEIF--------ELKAE
LNNEKKEKRKEAVKKVIAAMTVGKDVSSLFPDVVNCMQTDNLELKKLVYLYLMNYAKSQP
DMAIMAVNSFVKDCEDPNPLIRALAVRTMGCIRVDKITEYLCEPLRKCLKDEDPYVRKTA
AVCVAKLHDINAQMVEDQGFLDSLRDLIADSNPM--------------------------
VVANAVAALSEISESH---------------------PNSN--LLDLNPQNINKLLTALN
ECTEWGQIFILDCLSNY----------NPKDEREAQSIC-------ERVTPRLS-HANSA
VVLSAVKVLM--KFLELL-PKDSDYYTMLLKKLAP----PLVTLLSGE-PEVQYVALRNI
NLIVQKR-----------PEILKQEIKVFFVKYNDPIYVKLEKLDIMIRLASQANIAQ--
-VLAELKEYATEVDVDFVRKAVRAIGRCAIKV--EQSAE---------RCVSTLLDLIQT
KVN-YVVQEAIVVIRDIFRKYPNKYE---SIIATLCENLDSLDEPD-------ARGAMIW
IVGEYAERIDN-ADELLESFLEGFHDESTQ---------------------VQLTLLTAI
VKLFLKKP-------SETQELVQQVLSLATQDSDNPDLRDRGYIYWRLLS--TD-----P
VTAKE--VV-LSEKPLISEETDLIEPT--LLDELICHIGSLASVYHKPPNAFVE----GS
HGVHRKHLPIQHGS-----IDIGDSP-VGPTPSAGLEQPQ-VIPSQ-----GDLLGDLLN
LDLGPPGNVPQV--STMQMGAV-------DLLGGGLD-SLL-----GSDLGGGIGGSPAV
GQ-------------------TFIPSSVPATFA--PSPTPAVVSSGLNDLFELSSGIGMA
P------GGYVSQKAV---------------------WLPAVKAKGLEISGTFSHRQAHI
Y-----MDMSFTNKALQHMTDFAIQFNKNSF--GVIPSAPL-------------------
-----AIHTPLMPNQSIDISLPLNTLGPVMK-----------MEPLNNLQ----------
----------------------VAV-KNNIDVFYFSCLIPLHVLFVEDGKM---------
---ERQVFLATWKDIPNENELQFQIKDCH-LNA----DTVSSKLQNNNVYTIAKRNVEGQ
DMLYQ--SLKLTNGIWILAELRIQPGNPNYT---LS----------LKC----------R
A-------PEVCNYV-------YQVYDSILKN-
>gi|150866746|ref|XP_001386441.	Pichia stipitis
-----------------------MSLERKIRSFLTGPRK----GETF--------ELKSG
LVSQYKHERKDAIQRVIQAMTVGKDVSSLFPDVLKNIATYDLEQKKLVYLYLMNYAKTHP
ELCILAVNTFVQDTEDPNPLVRALAIRTMGCIRVNKMVDYMEIPLQRTLQDENPYVRKTA
ALCVAKLFDLNPEMCVEFGFLDQLKGLIKDSNPM--------------------------
VVANSLNALYEIRDMN---------------------SDANLEIFTADTETVKNLLMCLN
ECTEWGRITILTTLNEY----------HTDDAEEANHII-------ERVTPQLQ-HVNPS
VVLSSIRAII--HHIDAI-PVTAQ-RAAILKKLSA----PLVSLVSSSIPEAQYVGLKNI
RIILEKY-----------PQILSKELRVFFIKYSDPLYLKLEKLEIMVRLANDSNSAL--
-LLGELKEYAMEFEPSLVAKAIKSIGSVAIKL--SGSTV---------KAINLLNSLIDH
RGGDLVINESIVVLTNILRRYPGKNDLITLIIPVISNHISELERSD-------AMSGYIW
LLGEYPKYFSN-LHDKLQVLIDDFLSFESV---------------------LQLNILTAI
VKINLSASG------SKYSSLLQKVLESSTKDCENADVRDKAYIYWRLLS-SSS-----T
ESQKE--II-LTKLPPITTTIASFNPV--VLESLVEELSTLSSVYHKPAFTFID------
PNAAHSHVAQGN-------KSRSSSKKDNIEDLTNLAKQE-IIN-------NAKNENLLD
FDDDD------------------------DALTGDNG-----------------------
-----------------------------------AAEGSGSLLDELNDLFSAPVPVSQ-
-------GQQTQPSSN--------------------------------------------
------------NDILSLF--------------GAIPQNAP-------------------
-----T--------------------------------------PVSNVT----------
------------------------------------------------------------
--------------------------------------------QGLNNFNIGSN-----
-------------------------AAPSNT-----------------------------
----------------------SKLNNDLLDLM
>gi|58270770|ref|XP_572541.1|	Cryptococcus neoformans
-----------------------MA--------MAPPRK----GENW--------ELRQQ
LNSEYRDKRADAIKRVIANHTIGKDCSGLFPDVVKNMQTDDLEQKKLVYLYLMNYAKTQP
ELVILAVNTFVKDTADPNPLVRALAIRTMSILRAEKILDYLASPLSRCLKDENPYVRKTA
ALCVAKVFDLKPELAIEYGFIETLRDLIGDGNPM--------------------------
VVANAVAALGDIHEASLNLPSSQPGSPNDDESPSSVRPNQS--LFIIDPATLTKLLVALN
ECSEWGRIAILTTLARY----------RTNDEKESEHIC-------ERVMPQFQ-HVNAA
VVLGAVKVIM--IHMKNV-TKE-DLLKSLTRKMAP----PLVTLISSP-PEVQWVALRNI
NLLLQKR-----------PDILASEMRVFFCKYNDPSYVKVEKLEIMVRLANEKNVDT--
-LLGELKEYASEVDVDFVRKAVRAVGQVAIKI--DEAAG---------RCVEVLMELIET
RVS-YVVQEAVIVVKDIFRKYPHSYE---GIIPALCANLEELDEXE-------AKASLIW
LIGEYAEKIEN-ADELLGAFLETFSEESYP---------------------VQLQTLTAI
VKLFLKKP-------DESQAIVQKVLQAATKDCDSPDVRDRAYIYWRLLS--SD-----P
AAAKS--VV-LSVRPPISLPQTTVAPA--ILEELIGEISTLASVYHKPAATFIGKGRLGA
DEMHKKSLDAE--------DDVSREKALQA-----------VVA-------GNQAENLLD
FDDEPT--------PTNGESSI-------PAPGAGLGISSQ-------------------
-----------------------------------AIASAAKSTNPLDELMDLFSTASMT
T-------PVVQP------------------------GQPAAQA----------------
------QTSAQSSGGLGGLNGLA----------GL--SSPP-------------------
-----Q------------------SVSP--------------------------------
------------------------------------------------------------
------------------------------------------------------------
-----------------------QPGAPQSQ---------------KQQ----------Q
Q---------------------AAAQDDLLGLF
>gi|73966791|ref|XP_537725.2|	Canis familiaris
-----------------------MTDSKY----FTTNKK----GEIF--------ELKAE
LNNEKKEKRKEAVKKVIAAMTVGKDVSSLFPDVVNCMQTDNLELKKLVYLYLMNYAKSQP
DMAIMAVNSFVKDCEDPNPLIRALAVRTMGCIRVDKITEYLCEPLRKCLKDEDPYVRKTA
AVCVAKLHDINAQMVEDQGFLDSLRDLIADSNPM--------------------------
VVANAVAALSEISESH---------------------PNSN--LLDLNPQNINKLLTALN
ECTEWGQIFILDCLSNY----------NPKDDREAQSIC-------ERVTPRLS-HANSA
VVLSAVKVLM--KFLELL-PKDSDYYNMLLKKLAP----PLVTLLSGE-PEVQYVALRNI
NLIVQKR-----------PEILKQEIKVFFVKYNDPIYVKLEKLDIMIRLASQANIAQ--
-VLAELKEYATEVDVDFVRKAVRAIGRCAIKV--EQSAE---------RCVSTLLDLIQT
KVN-YVVQEAIVVIRDIFRKYPNKYE---SIIATLCENLDSLDEPD-------ARAAMIW
IVGEYAERIDN-ADELLESFLEGFHDESTQVSSYLCLQFLTPTTQVGDKWLVQLTLLTAI
VKLFLKKP-------SETQELVQQVLSLATQDSDNPDLRDRGYIYWRLLS--TD-----P
VTAKE--VV-LSEKPLISEETDLIEPT--LLDELICHIGSLASVYHKPPNAFVE----GS
HGIHRKHLPIHHGS-----TDAGDSP-VGTTTATNLEQPQ-VIPSQ-----GDLLGDLLN
LDLGPPVNVPQV--SSMQMGAV-------DLLGGGLD-SLV-------------------
GQ-------------------SFIPSSVPATFA--PSPTPAVVSSGLNDLFELSTGIGMA
P------GGYVAPKAV---------------------WLPAVKAKGLEISGTFTHRQGHI
Y-----MEMNFTNKALQHMTDFAIQFNKNSF--GVIPSTPL-------------------
-----AIHTPLMPNQSIDVSLPLNTLGPVMK-----------MEPLNNLQ----------
----------------------VAV-KNNIDVFYFSCLIPLNVLFVEDGKM---------
---ERQVFLATWKDIPNENELQFQIKECH-LNA----DTVSSKLQNNNVYTIAKRNVEGQ
DMLYQ--SLKLTNGIWILAELRIQPGNPNYT---LS----------LKC----------R
A-------PEVSQYI-------YQVYDSILKN-
>gi|118795034|ref|XP_321886.3|	Anopheles gambiae
-----------------------MTDSKY----FTTTKK----GEIF--------ELKSE
LNNDKKEKKKEAVKKVIASMTVGKDVSALFPDVVNCMQTDNLELKKLVYLYLMNYAKSQP
DMAIMAVNTFVKDCEDTNPLIRALAVRTMGCIRVDKITEYLCEPLRKCLKDEDPYVRKTA
AVCVAKLYDISSSMVEDQGFLDQLKDLLSDSNPM--------------------------
VVANAVAALSEINEAS---------------------ASGQ-PLVEMNSVTINKLLTALN
ECTEWGQVFILDSLANY----------TPKDEREAQSIC-------ERITPRLA-HANAA
VVLSAIKVLM--KLLEIL-AGDNDFCSMLTKKLAP----PLVTLLSSE-PEVQYVALRNI
NLIVQKR-----------PDILKHEMKVFFVKYNDPIYVKLEKLDIMIRLANQSNIAQ--
-VLSELKEYATEVDVDFVRKAVRAIGRCAIKV--EPSAE---------RCVSTLLDLIQT
KVN-YVVQEAIVVIKDIFRKYPNKYE---SIISTLCENLDTLDEPE-------ARASMVW
IIGEYAERIDN-ADELLDGFLEGFQDENAQ---------------------VQLQLLTAV
VKLFLKRP-------ADTQELVQHILSLATQDSDNPDLRDRGFIYWRLLS--TD-----P
AAAKE--VV-LADKPLISEETDLLEPT--LLDELICHISSLASVYHKPPTAFVE----GR
GAGVRKSLPNRSAS-------------AAGEDSSSVQEAT-VIPNQ-----ESLIGDLLS
MDIGAPAAPAA---PAPASSNV-------DLLGGGLD-ILL-------------------
---------------------GGAAP---------APAGGSAAGGLLGDIFGIGPV--SS
S------NMIQIPKIT---------------------WLPADKGKGLEIQGTFSRRAGQV
Y-----MDMTFTNKAMQAMTGFAIQLNKNSF--GLVPSAPL-------------------
-----Q-VAPLQPSQSVDTSLALGTTGPVQR-----------MEPLNNLQ----------
----------------------VAI-KNNVDIFYFACLVHGNVLFVEDGQL---------
---DKRVFLTTWKEIPAANEIQYNLHGIV-GTA----DTVAAKMTANSIFTIAKRNVEGQ
DMLYQ--SLKLTNNIWVLLELKLSPGSSDAT---LS----------LKT----------R
S-------VEVGAII-------FAAYEQIIRSP
>gi|91082649|ref|XP_970593.1|	Tribolium castaneum
MLTSSSHVSNNGSYSNDRGA---GLEAEY----VVDPAS----GGFFHTDFKKHDDLKEM
LDSNKDSLKLEAMKRIIGMVAKGRDASMLFPAVVKNVVSKNIEVKKLVYVYLERYAEEQQ
DLALLSISTFQRALKEPNQLIRAGALRVLSSIRVKMISPIVMLAIRDASSDMSPYVRKTA
AHAIPKLYSLENELKSE--LVTIIQKLLADKTVL--------------------------
VIGSAVMAFTEVC------------------------PERV----DLIHQVYRKLCALLV
DVDEWGQVTIVNMLTRYARMQFADPNLHSRGDDSDRPFYDSGSDSSEKPAPTLD--PDHR
LLLRSTRPLLQSRNAAVVMAVAQLYHHAAPKSESPLAAKAMVRLLRSH-VEVQSVVLNAI
ASISAQN-----------KGMFEAYLKSFFVRTSDPTNIKLLKLEILTNLTTDSNVSI--
-ILRELQTYISNSDKKFVAATIQAIGRCACSI--NEVTD---------SCLSGLVSLLSN
RDE-AVVAESVVVIKKLLQTQAADPK---EIITHMARLLDSITVAQ-------ARAAILW
LLGEHSQKVPNIAPDILRKLAKTFSDEHDI---------------------VKLQVMNLA
VKLYITNS-------EQTALLCQYIFNLARYD-QNYDIRDKARLFKQFIPQQNG-----R
IASQSARIF-LASKPAPLLQSHFKDHEDLQLGSLSHYIKQRATGY-EPLPPFPEN---PP
PGDVRNVEPIV--------IEDSKSYKKSDKKGKDM-----FLWES-----GSSRGASSN
NSSDSSDSSSSSSDSSSEDSESQ-----YEEESSSDEKSAS-------------------
-------------------CTSSEESSSEESEEEAKKPEAPKPKSNLDLLLDLGDVDSTA
PVMTPSLGGFLTPSVVSTTPSQVEMTPPVFTNTKTIELINKINGRGLSATYRFTRTPHIL
SPSMANINIMFTNNTTEDISDIRLGKKNLGLDMSMYEFANI-------------------
-----A---RLPPNGCLPASLGIDFNDTTQP---------------ANFE----------
----------------------IVCSLGNFSV----CIKPTIGELVRPVRM---------
---DTPTFQEKQSKLGGMNEHIGKV-KCV--------SNIVERVTECSNLGVCDPASDSL
SLVYRFAGQTLKSSNFVLVTITKQEV--------VT----------VNC----------E
N-------MVFGSVM-------LNELLHNLKS-
>gi|18034787|ref|NP_542150.1|	Rattus norvegicus
-----------------------MTDSKY----FTTNKK----GEIF--------ELKAE
LNNEKKEKRKEAVKKVIAAMTVGKDVSSLFPDVVNCMQTDNLELKKLVYLYLMNYAKSQP
DMAIMAVNSFVKDCEDPNPLIRALAVRTMGCIRVDKITEYLCEPLRKCLKDEDPYVRKTA
AVCVAKLHDINAQMVEDQGFLDSLRDLIADSNPM--------------------------
VVANAVAALSEISESH---------------------PNSN--LLDLNPQNINKLLTALN
ECTEWGQIFILDCLSNY----------NPKDDREAQSIC-------ERVTPRLS-HANSA
VVLSAVKVLM--KFLELL-PKDSDYYNMLLKKLAP----PLVTLLSGE-PEVQYVALRNI
NLIVQKR-----------PEILKQEIKVFFVKYNDPIYVKLEKLDIMIRLASQANIAQ--
-VLAELKEYATEVDVDFVRKAVRAIGRCAIKV--EQSAE---------RCVSTLLDLIQT
KVN-YVVQEAIVVIRDIFRKYPNKYE---SIIATLCENLDSLDEPD-------ARAAMIW
IVGEYAERIDN-ADELLESFLEGFHDESTQ---------------------VQLTLLTAI
VKLFLKKP-------SETQELVQQVLSLATQDSDNPDLRDRGYIYWRLLS--TD-----P
VTAKE--VV-LSEKPLISEETDLIEPT--LLDELICHIGSLASVYHKPPNAFVE----GS
HGIHRKHLPIHHGS-----TDAGDSP-VGTTTATNLEQPQ-VIPSQ-----GDLLGDLLN
LDLGPPVNVPQV--SSMQMGAV-------DLLGGGLD-SLL-----GSDLGGGIGGSPAV
GQ-------------------SFIPSSVPATFA--PSPTPAVVSSGLNDLFELSTGIGMA
P------GGYVAPKAV---------------------WLPAVKAKGLEISGTFTHRQGHI
Y-----MEMNFTNKALQHMTDFAIQFNKNSF--GVIPSTPL-------------------
-----AIHTPLMPNQSIDVSLPLNTLGPVMK-----------MEPLNNLQ----------
----------------------VAV-KNNIDVFYFSCLIPLNVLFVEDGKM---------
---ERQVFLATWKDIPNENELQFQIKECH-LNA----DTVSSKLQNNNVYTIAKRNVEGQ
DMLYQ--SLKLTNGIWILAELRIQPGNPNYT---LS----------LKC----------R
A-------PEVSQYI-------YQVYDSILKN-
>gi|110748751|ref|XP_624446.2|	Apis mellifera
MLTAAANSLSNNGGSYSNDRPSNTADAEL----ATDPAS----GGFFHSDYKKHEDLKQM
LDSNKDGLKLEAMKRIIGMIAKGRDASELFPAVVKNVVSKNIEVKKLVYVYLVRYAEDQQ
DLALLSISTFQRALKDPNQLIRASALRVLSSIRVSMIVPIVMLAIKDSASDMSPYVRKTA
AHAIPKLYSLDSEQKEE--LIGVLEKLLSDKTTL--------------------------
VVGSAVMAFEEVC------------------------PERI----DLIHKNYRKLCNLLV
DVDEWGQVVIVNMLTRYARTQFINPNVDNIEDDENRPFYDSDSDSSNTKKPKLTIDPDHR
LLLRNTKPLLQSRNASVVMAVSQLYHHTAPRSEVMIAAKALIRLLRGH-REVQSIVLHCI
ASISIAR-----------KGMFEPFLKSFFVRTSDPTHIKLLKLDILTNLATETSIGV--
-ILREFQTYISSSDKEFVGASIQAIGRCASNI--KEVTD---------TCLNGLVSLLSN
RDE-AVVAESVVVIKKLLQTQSNEHK---NIIAHMAKLMDFITIPQ-------ARASILW
LLGEYSDRVPKIAPDVLRKMAKNFVNEQDI---------------------VKLQILNLA
VKLCLNNP-------IQTKPFCQYVFQLAKYD-QNYDIRDRARFLRHFIFDEDGHKKNLP
QLAKR--IF-LAPKPAPTLTSRFKNSE-YQLGTLSHYLDMPCAGY-RPLPPFPD----VA
PDPSLRDVSNSTMR-----DTRDEYYRKDKKDKKGKEKEKPFYSDE-----ESVQADELN
NENESSDTTTSDSSDEESDSSEY-----ISESGKSETDSEKKKSVKLSDESNSETESEES
DSEDSS---------------TNSQESKETKYKTLNEEAKEKPKSNIDLLLDLDDVIPMT
PIMPLSTGGLLTPINLNITNDIREVSAS-FTPIRKSELLNSITGHGLKIEYRFTRSQHLV
SAYLVTIELTFSNEGNELIKEIQMGVKNLPK--GMLIHDFT-------------------
-----K-IPLLEINSNLSSTLGINFNDSTQP---------------ANFN----------
----------------------IDFVIGDETNSCPVIIKAPIGEIIRAVLL---------
---QENMFLTEKTKLKGMNEHVAKV-----QYSG-NKNIISQKIFETA--NVAMVSSNDE
EIRFA--AYTLASKSLVLVTIKIISNECLE----IC----------VNC----------E
K-------MVIGSIL-------LNELKSNLKIN
>gi|114668034|ref|XP_001174142.	Pan troglodytes
-----------------------MTDSKY----FTTNKK----GEIF--------ELKAE
LNNEKKEKRKEAVKKVIAAMTVGKDVSSLFPDVVNCMQTDNLELKKLVYLYLMNYAKSQP
DMAIMAVNSFVKDCEDPNPLIRALAVRTMGCIRVDKITEYLCEPLRKCLKDEDPYVRKTA
AVCVAKLHDINAQMVEDQGFLDSLRDLIADSNPM--------------------------
VVANAVAALSEISESH---------------------PNSN--LLDLNPQNINKLLTALN
ECTEWGQIFILDCLSNY----------NPKDDREAQSIC-------ERVTPRLS-HANSA
VVLSAVKVLM--KFLELL-PKDSDYYNMLLKKLAP----PLVTLLSGE-PEVQYVALRNI
NLIVQKR-----------PEILKQEIKVFFVKYNDPIYVKLEKLDIMIRLASQANIAQ--
-VLAELKEYATEVDVDFVRKAVRAIGRCAIKV--EQSAE---------RCVSTLLDLIQT
KVN-YVVQEAIVVIRDIFRKYPNKYE---SIIATLCENLDSLDEPD-------ARAAMIW
IVGEYAERIDN-ADELLESFLEGFHDESTQ---------------------VQLTLLTAI
VKLFLKKP-------SETQELVQQVLSLATQDSDNPDLRDRGYIYWRLLS--TD-----P
VTAKE--VV-LSEKPLISEETDLIEPT--LLDELICHIGSLASVYHKPPNAFVE----GS
HGIHRKHLPIHHGS-----TDAGDSP-VGTTTATNLEQPQ-VIPSQ-----GDLLGDLLN
LDLGPPVNVPQV--SSMQMGAV-------DLLGGGLD-SLV-------------------
GQ-------------------SFIPSSVPATFA--PSPTPAVVSSGLNDLFELSTGIGMA
P------GGYVAPKAV---------------------WLPAVKAKGLEISGTFTHRQGHI
Y-----MEMNFTNKALQHMTDFAIQFNKNSF--GVIPSTPL-------------------
-----AIHTPLMPNQSIDVSLPLNTLGPVMK-----------MEPLNNLQVKSKENNWMD
TSGRENANIMEKGIQAPFKVRKVAV-KNNIDVFYFSCLIPLNVLFVEDGKM---------
---ERQVFLATWKDIPNENELQFQIKECH-LNA----DTVSSKLQNNNVYTIAKRNVEGQ
DMLYQ--SLKLTNGIWILAELRIQPGNPNYT---LS----------LKC----------R
A-------PEVSQYI-------YQVYDSILKN-
>gi|71000004|ref|XP_754719.1|	Aspergillus fumigatus
-----------------------MAMSRIRGA-FAVPRK----GETF--------ELRAG
LVSQYAYERKEAIQKTIMAMTLGKDVSALFPDVLKNIATSDLEQKKLVYLYLMNYAKSHP
DLCILAVNTFVQDSEDPNPLIRALAIRTMGCIRVDKMVDYMEEPLRKTLRDESPYVRKTA
AICVAKLFDLNPSLCLENGFLEMLQEMIGDPNPM--------------------------
VVANSVTALSEIHHAA---------------------PETR--ALQVTSNVLRKLLMALN
ECTEWGRVTILTTLAEY----------KTSDVTESEHIC-------ERVAPQFQ-HANPS
VVLAAVKVVF--LHMKNI---KQELSSNYLKKMAP----PLVTLVSSA-PEVQYVALRNI
DLLLQKQ-----------PDILNKELRVFFCKYNDPPYVKFQKLEIMVRIANDRNVDQ--
-LLAELREYALEVDMDFVRRAVRAIGQVAIKI--ESSCE---------KCVNTLLDLINT
KVN-YVVQEAIVVIKDIFRKYPG-YE---GIIPTLCKCIDELDEPN-------ARAALIW
IVGEYAEKISN-AGDILAGFVEGFNEEFSQ---------------------TQLQILTAV
VKLFLKRP-------EKAQGLVQKVLQAATAENDNPDVRDRAYVYWRLLSNTSD-----P
NATKN--IV-LSQKPPIVTTIHSLPPA--LLEQLIGELSTLASVYHKPPEQFVGQGRFGA
DAVQRAAIEEQI-------QNARENPLAAAAAAAAVTGAT-PPPQA-----QNNVENLLD
IDFDGAAPASTQKEPASGMSGL-------EGLAG----TPV-------------------
---------------------RVESPAVGS-----PAPAA---SNNLDDLLGVFGDSGST
S------ASAST----------------------------AIPNGG--------------
------------GAAADLMNGFS----------GLDLSANT-------------------
-----G------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-------------------------GNQQ-------------------------------
----------------------RKTNEDILSLF
>gi|108872022|gb|EAT36247.1|	Aedes aegypti
-----------------------MTDSKY----FTTTKK----GEIF--------ELKSE
LNNDKKEKKKEAVKKVIASMTVGKDVSALFPDVVNCMQTDNLELKKLVYLYLMNYAKSQP
DMAIMAVNTFVKDCEDTNPLIRALAVRTMGCIRVDKITEYLCEPLRKCLKDEDPYVRKTA
AVCVAKLYDISSSMVEDQGFLDQLKDLLSDSNPM--------------------------
VVANAVAALSEINEAS---------------------ASGQ-PLVEMNSATINKLLTALN
ECTEWGQVFILDSLANY----------TPKDEREAQSIC-------ERITPRLA-HANAA
VVLSAIKVLM--KLLEIL-ASDSDFCAMLTKKLAP----PLVTLLSSE-PEVQYVALRNI
NLIVQKR-----------PDILKHEMKVFFVKYNDPIYVKLEKLDIMIRLANQSNIAQ--
-VLSELKEYATEVDVDFVRKAVRAIGRCAIKV--EPSAE---------RCVSTLLDLIQT
KVN-YVVQEAIVVIKDIFRKYPNKYE---SIISTLCENLDTLDEPE-------ARASMVW
IIGEYAERIDN-ADELLDSFLEGFQDENAQ---------------------VQLQLLTAV
VKLFLKRP-------ADTQELVQHVLSLATQDSDNPDLRDRGFIYWRLLS--TD-----P
AAAKE--VV-LADKPLISEETDLLEPT--LLDELICHISSLASVYHKPPTAFVE----GR
GAGVRKSLPNRS---------------ASAAGEEAVPEAT-VIPNQ-----ESLIGDLLS
MDIGAPAAPAA---PVANTSNV-------DLLGGGLD-ILL---------------GPNL
NE-------------------TTNNAAAPAAS---TAAAAGGAGGLLGDIFGIGPAATT-
-------NMIQIPKIT---------------------WLPADKGKGLEVQGTFSRRNGQI
F-----MDMTFTNKAMQAMTGFAIQLNKNSF--GLVPAAPL-------------------
-----Q-VAPLQPSQSTEASLQLGTTGPVQR-----------MEPLNNLQ----------
----------------------VAI-KNNVDIFYFACLVHGNVLFVEDGQL---------
---DKRVFLTTWKEIPAANEIQFNLHGIT-GTA----DTVAAKMTANNIFTIAKRNVEGQ
DMLYQ--SLKLTNNIWVLLELKLSPGSPDAT---LS----------LKT----------R
S-------VEVGSII-------FAAYEQIIRSP
>gi|50286151|ref|XP_445504.1|	Candida glabrata
------------------MPPLDKRIKKFLKDSVRVAPKISSKGELA--------ELRAG
LVSPYSQTRKDAIKKTIQQMTLGKDVSSLFPDVLKNIATNDVEQKKLVYLYVMNYAETHP
ELCILAVNTFIQDAQDPNPLIRCMAIRTMSLIRVEKILEYIETPLRKTLQDDNPYVRKTA
VICVAKLFQLNKQLCVELGVLEDLQSALDDSNPM--------------------------
VVANATAALVEINNMD---------------------PTAV-KLPQLIQSHVSQFLLALN
ECTEWARITILTALAEY----------SARDGVEAQDII-------DRVTAHLQ-HVNPA
VVLATIKVII--QNLPLIIADNSSKRASIMKKLSS----ALVSLMSTP-PEMQYVALKNI
RIVLEKY-----------PELLTKELRIFYIKFNDPLYVKVEKIDILVRLVDPSNLKQCN
LLLAELKEYAMDFEPEFVSRVILALSQLAIKYSDLPFIQ---------KVMDILVELLEV
RE--KSKDDCCSAAIDLLRHTNNNAE----LAKQLCSVLNSWESPEIELTTDAAKCKYIW
IMGQYPRLFSS-LESKMKGFVDNFVNENTS---------------------TQMSILITT
VRLHNMLP----------SDLLQSVLDTSTKETKELDVRDMAMVYWRTLSLPNV-----D
ELINS--LC-SSQVPQINSTIDQFSPE--LLEKLLRQLGNISSINFKLDS--------GN
KRVKYVQNIVNN-------KQLEELQDIAKNELENKANDD-VLLDF-----GDEDDDMMS
TSNNNNSTPQP---------------------------SAL-------------------
--------------------------------------------SELDDLF---------
------------------------------------------------------------
---------------------------------GFSSTNAT-------------------
-----V------------------------------------------------------
------------------------------------------------------------
-------------------------------------GSVSQKVENLN------------
----------------------------------------------INE----------K
K---------------------STTTQDLLDLF
>gi|148235381|ref|NP_001080473.	Xenopus laevis
-----------------------MTDSKY----FTTNKK----GEIF--------ELKAE
LNNEKKEKRKEAVKKVIAAMTVGKDVSSLFPDVVNCMQTDNLELKKLVYLYLMNYAKSQP
DMAIMAVNSFVKDCEDPNPLIRALAVRTMGCIRVDKITEYLCEPLRKCLKDEDPYVRKTA
AVCVAKLHDINAQMVEDQGFLDSLRDLIADSNPM--------------------------
VVANAVAALSEISESH---------------------PNSN--LLDLNPQNISKLLTALN
ECTEWGQIFILDCLSNY----------NPKDEREAQSIC-------ERVTPRLS-HANSA
VVLSAVKVLM--KFIELL-PKDSDYYTMLLKKLAP----PLVTLLSGE-PEVQYVALRNI
NLIVQKR-----------PEILKQEIKVFFVKYNDPIYVKLEKLDIMIRLASQANIAQ--
-VLAELKEYATEVDVDFVRKAVRAIGRCAIKV--EQSAE---------RCVSTLLDLIQT
KVN-YVVQEAIVVIRDIFRKYPNKYE---SIIATLCENLDSLDEPD-------ARGAMIW
IVGEYAERIDN-ADELLESFLEGFHDESTQ---------------------VQLTLLTAI
VKLFLKKP-------SETQELVQQVLSLATQDSDNPDLRDRGYIYWRLLS--TD-----P
VTAKE--VV-LSEKPLISEETDLIEPT--LLDELICHIGSLAFVYHKPPNAFVE----GS
HGVHRKHLPIQHGS-----IDIGDSP-VGPTPSAGLEQPQ-VIPSQ-----GDLLGDLLN
LDLGPPGNVPQV--STMQMGAV-------DLLGGGLD-SLL-----GSDLGGGIGGSPAV
GQ-------------------TFIPSSVPATFA--PSPTPAVVSSGLNDLFELSSGIGMA
P------GGYVAPKAV---------------------WLPAVKAKGLEISGTFSHRQSHI
Y-----MDMTFTNKALQHMTDFAIQFNKNSF--GVIPSAPL-------------------
-----AIHTPLMPNQSIEISLPLNTLGPVMK-----------MEPLNNLQ----------
----------------------VAV-KNNIDVFYFSCLIPLHVLFVEDGKM---------
---ERQVFLATWKDIPNENELQFQIKDCH-LNA----DTVSSKLQNNNVYTIAKRNVEGQ
DMLYQ--SLKLTNGIWILAELRIQPGNPNYT---LS----------LKC----------R
A-------PEVCNYV-------YQVYDSILKN-
>gi|121705304|ref|XP_001270915.	Aspergillus clavatus
-----------------------MAMSRIRGA-FAVPRK----GETF--------ELRAG
LVSQYAYERKEAIQKTIMAMTLGKDVSALFPDVLKNIATSDLEQKKLVYLYLMNYAKSHP
DLCILAVNTFVQDSEDPNPLIRALAIRTMGCIRVDKMVDYMEEPLRKTLRDESPYVRKTA
AICVAKLFDLNPSLCLENGFLEMLQEMIGDPNPM--------------------------
VVANCVTALSEIQHAA---------------------PETR--ALQVASNTLRKLLMALN
ECTEWGRVTILTTLAEY----------KTSDVTESEHIC-------ERVAPQFQ-HANPS
VVLAAVKVVF--LHMKNV---KQDLSANYLKKMAP----PLVTLVSSA-PEVQYVALRNI
DLLLQKQ-----------PDILNKELRVFFCKYNDPPYVKFQKLEIMVRIANDRNVDQ--
-FLAELKEYALEVDMDFVRRAVRAIGQVAIKI--ESACE---------KCVNTLLDLINT
KVN-YVVQEAIVVIKDIFRKYPG-YE---GIIPTLCQCIDELDEPN-------ARAALIW
IVGEYAEKISN-AGDILAGFVEGFNEEFSQ---------------------TQLQILTAV
VKLFLKRP-------EKAQGLVQKVLQAATAENDNPDVRDRAYVYWRLLSNTSD-----P
NATKN--IV-LSQKPPIVTTIHSLPPT--LLDQLISELSTLASVYHKPPEQFVGQGRFGA
DAVQRAAIEEQI-------QNARENPLAAAAAAAAVTGAT-PPPQS-----QNNMENLLD
IDFDGGAPASAQKEPPSGMSGL-------EGLAG----TPV-------------------
---------------------RVESP---------AVGAPAQPSNNLDDLLGVFGDSG--
-------GAAASANTA------------------------APNGSG--------------
-----------SGATADLMNGFA----------GLDLSANT-------------------
-----T------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
--------------------------SPS-------------------------------
--------PEANQQ--------RKTNEDILSLF
>gi|115384786|ref|XP_001208940.	Aspergillus terreus
-----------------------MAMSRIRGA-FAVPRK----GETF--------ELRAG
LVSQYAYERKESIQKTIMAMTLGKDVSALFPDVLKNIATNDLEQKKLVYLYLMNYAKSHP
DLCILAVNTFVQDSEDPNPLIRALAIRTMGCIRVDKMVDYMEEPLRKTLRDESPYVRKTA
AICVAKLFDLNPGMCLENGFLEMLQEMIGDPNPM--------------------------
VVANSVTALSEIHHAA---------------------PETN--ALQVTTNTLRKLLMALN
ECTEWGRVTILTTLAEY----------KTLEVTESEHIC-------ERVAPQFQ-HANPS
VVLAAVKVVF--LHMRNI---NPELSKNYLKKMAP----PLVTLVSSA-PEVQYVALRNI
DLLLQKQ-----------PDILNKELRVFFCKYNDPPYVKFQKLEIMVRIANDRNVDQ--
-LLSELKEYALEVDMDFVRRAVKAIGQVAIKI--ESASE---------KCVNTLLDLINT
KVN-YVVQEAIVVIKDIFRKYPG-YE---GIIPTLCKCIDELDEPN-------ARAALIW
IVGEYAEKISN-AGDILGGFVEGFNEEFSQ---------------------TQLQILTAV
VKLFLKRP-------EKAQGLVQKVLQAATAENDNPDVRDRAYVYWRLLSNTSD-----P
GATKN--IV-LSEKPPIVTTIHSLPPA--LLEQLLAELSTLASVYHKPPEQFVGQGRFGA
DAVQRAAIEEQI-------QNARENPLAAAAAAAAVTGKT-PPPQT-----QNNVENLLD
IDFDGTAPASAHKEPGGGMSGL-------EGLAG----TPV-------------------
---------------------RVES----------PAAGAPAGSNNLDDLLGVFGDGGSA
-------GGAAASSAT--------------------------------------------
---------PNGGAGADLMNGFA----------GLDLSGNN-------------------
-----TTSPP--------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------PGGSQ-------------------------------
--------P-------------KKTNEDILSLF
>gi|118100169|ref|XP_415772.2|	Gallus gallus
-----------------------MTDSKY----FTTNKK----GEIF--------ELKAE
LNNEKKEKRKEAVKKVIAAMTVGKDVSSLFPDVVNCMQTDNLELKKLVYLYLMNYAKSQP
DMAIMAVNSFVKDCEDPNPLIRALAVRTMGCIRVDKITEYLCEPLRKCLKDEDPYVRKTA
AVCVAKLHDINAQMVEDQGFLDSLRDLIADSNPM--------------------------
VVANAVAALSEISESH---------------------PNSN--LLDLNPQNINKLLTALN
ECTEWGQIFILDCLSNY----------NPKDDREAQSIC-------ERVTPRLS-HANSA
VVLSAVKVLM--KFLELL-PKDSDYYNMLLKKLAP----PLVTLLSGE-PEVQYVALRNI
NLIVQKR-----------PEILKQEIKVFFVKYNDPIYVKLEKLDIMIRLASQANIAQ--
-VLAELKEYATEVDVDFVRKAVRAIGRCAIKV--EQSAE---------RCVSTLLDLIQT
KVN-YVVQEAIVVIRDIFRKYPNKYE---SIIATLCENLDSLDEPD-------ARAAMIW
IVGEYAERIDN-ADELLESFLEGFHDESTQ---------------------VQLTLLTAI
VKLFLKKP-------SETQELVQQVLSLATQDSDNPDLRDRGYIYWRLLS--TD-----P
VTAKE--VV-LSEKPLISEETDLIEPT--LLDELICHIGSLASVYHKPPNAFVE----GS
HGIHRKHLPIHHGS-----TDAGDSP-VGTTATTNLEQPQ-VIPSQ-----GDLLGDLLN
LDLGPPVNVPQV--SSMQMGAV-------DLLGGGLD-SLL-----GSDLGGGIGGSPAV
GQ-------------------TYIPSSVPATFA--PSPTPAVVSSGLNDLFELSSGIGMA
P------GGYVAPKSV---------------------WLPAVKAKGLEISGTFSHRQGHI
Y-----MEMNFTNKALQHMTDFAIQFNKNSF--GVIPSTPL-------------------
-----AIHTPLMPNQSIDVSLPLNTLGPVMK-----------MEPLNNLQ----------
----------------------VAV-KNNIDVFYFSCLIPLNVLFVEDGKM---------
---ERQVFLATWKDIPNENELQFQIKDCH-LNA----DTVSSKLQNNNVYTIAKRNVEGQ
DMLYQ--SLKLTNGIWILAELRIQPGNPNYT---LS----------LKC----------R
A-------PEVSQYI-------YQAYDAILKN-
>gi|149521471|ref|XP_001517132.	Ornithorhynchus anatinus
-----------------------MTDSKY----FTTTKK----GEIF--------ELKAE
LNSDKKEKKKEAVKKVIASMTVGKDVSALFPDVVNCMQTDNLELKKLVYLYLMNYAKSQP
DMAIMAVNTFVKDCEDPNPLIRALAVRTMGCIRVDKIXXXXXX---------DPYVRKTA
AVCVAKLHDINAQLVEDQGFLDTLKDLISDSNPM--------------------------
VVANAVAALSEIAESH---------------------PNSN--LLDLNPQSNNKLLTALN
ECTEWGQIFILDCLANY----------MPKDDRKAASVA-------QTTTGQRQ-FPSMS
VLLSRTFLSL--DQGSSV-TNDLDERGDLAKQGSP----PPTPMPGPL-PSAQ----RST
AHIVSVQ-----------PEILKHEMKVFFVKYNDPIYVKLEKLDIMIRLASQANIAQ--
-VLAELKEYATEVDVDFVRKAVRAIGRCAIKV--EQSAE---------RCVSTLLDLIQT
KVN-YVVQEAIVVIKDIFRKYPNKYE---SVIATLCENLDSLDEPE-------ARAAMIW
IVGEYAERIDN-ADELLESFLEGFHDESTQ---------------------VQLQLLTAI
VKLFLKKP-------TETQELVQQVLSLATQDSDNPDLRDRGYIYWRLLS--TD-----P
VAAKE--VV-LAEKPLISEETDLIEPT--LLDELICYIGTLASVYHKPPSAFVE----GS
RGIVHKSLPPRTGS-----SESAESPEAAPAGAPPAEQPA-VIPTQ-----GDLLGDLLN
LDLGPPVSSPPVATSSVQMGAV-------DLLGGGLD-SLM------GDESEGMGGT---
---------------------GFTAPPAAV-----PANSGAPIGGGLGDLFDLTGGVGAL
S------GSYVAPKAV---------------------WLPAMKAKGLEISGTFSRQAGSI
S-----MDLSLTNKALQVMSDFAIQFNRNSSPPQRIPSTPVPAWGAGVAKVNRARWRQMK
HANMAALKLALLPSLCSGAGQGAGRAGSRVRGRVPGSGGGTLAKPGEELG----------
----------------------IALLQRSASVSAGSPPGPTSRARSRLGV----------
---RPAEAREPRGRFPVFPELRGGLGSHPRAGTR---KAVSSKLQGSHVFTIAKRNVEGQ
DMLYQ--SLKLTNGIWVLAELRIQPGNPSFTGVESPPSDEGSESAASPG----------R
GIRGRLILAESPSVHGTSWGLSIGSYSRIY---
>gi|151941672|gb|EDN60034.1|	Saccharomyces cerevisiae
------------------MPPLDKRIKKFLKDSIRIAPKISGKGELS--------ELRTG
LVSQYPQTRKDAIKKTIQQMTLGKDVSSLFPDVLKNIATIDVEQKKLVYLYVMNYAETHP
ELCILAVNTFITDAQDPNPLIRCMAIRTMSMIRVDKILEYIETPLRRTLHDDNAYVRKTA
VICVAKLFQLNKDLCVELGVVEDLVNALDDSNPL--------------------------
VIANATAALIEIHNMD---------------------MDAV-DLSSLIQSHVSQFLLALN
ECTEWARIIILGTLSEY----------SAKDSLEAQDII-------DRVTAHLQ-HVNPA
VVLATIKVIV--RNLPQI---EYSSNSLIMKRLSS----AFVSLMSTP-PEMQYVALKNI
RIILEKY-----------PELLTKELRIFYVKFNDPLYVKLEKIDILVRLVDPSNLKQCT
LLLTELKEYAMEYEPEFVSRAIQALSQLGIKYAQESFVS---------KVLDILLELLER
QD--TIKDDCCISLCDLLRHCPGNDK----MAKQVCAVFNTWSNPEVLLQSDIAKCNYVW
LLGQHPNNFSD-LESKINIFIENFVQEEAL---------------------TQMSLLMTI
VRLHA----------TLTGSMLQSVLELATQQTHELDVRDMAMMYWRCLSMPNN-----E
SLVND--LC-QSKLPMISNTLEKFSPE--VLEKLLMELGTISSIYFKPDSNRRKGKKYVQ
NIVKGKHIEE---------LESMAKNEISSKANDDV---------------------LLD
FDERDDVTNTNA--------------------------GML-------------------
--------------------------------------NTSTTLGDLDDLFDFG------
---------------------------------------PSEDATQINTNDT--------
-------------KAVQGLKELKLGGDSN----GISSGG---------------------
------------------------------------------------------------
--------------------------KNN-------------------------------
------------------------------------------------------------
------------------------------------------------------------
--------PDVSGG--------NIVSQDLLDLF
>gi|125981791|ref|XP_001354899.	Drosophila pseudoobscura
-----------------------MTDSKY----FTTTKK----GEIF--------ELKSE
LNNDKKEKKKEAVKKVIASMTVGKDVSALFPDVVNCMQTDNLELKKLVYLYLMNYAKSQP
DMAIMAVNTFVKDCEDSNPLIRALAVRTMGCIRVDKITEYLCEPLRKCLKDEDPYVRKTA
AVCVAKLYDISATMVEDQGFLDQLKDLLSDSNPM--------------------------
VVANAVAALSEINEAS---------------------QSGQ-PLVEMNSVTINKLLTALN
ECTEWGQVFILDSLANY----------SPKDEREAQSIC-------ERITPRLA-HANAA
VVLSAVKVLM--KLLEML-SSDSDFCATLTKKLAP----PLVTLLSSE-PEVQYVALRNI
NLIVQKR-----------PDILKHEMKVFFVKYNDPIYVKLEKLDIMIRLANQSNIAQ--
-VLSELKEYATEVDVDFVRKAVRAIGRCAIKV--EPSAE---------RCVSTLLDLIQT
KVN-YVVQEAIVVIKDIFRKYPNKYE---SIISTLCENLDTLDEPE-------ARASMVW
IIGEYAERIDN-ADELLDSFLEGFQDENAQ---------------------VQLQLLTAV
VKLFLKRP-------SDTQELVQHVLSLATQDSDNPDLRDRGFIYWRLLS--TD-----P
AAAKE--VV-LADKPLISEETDLLEPT--LLDELICHISSLASVYHKPPTAFVE----GR
GAGVRKSLPNRT-------TGAGVSSGAGDQQEPGAGSEAMVIPNQ-----ESLIGDLLS
MDINAPAMPA----APTATSNV-------DLLGGGLD-ILL-------------------
----------------------GGPP---------AEPAAGGASSLLGDIFGLAGT--SL
S------VGVQIPKVT---------------------WLPAEKGKGLEIQGTFSRRNGEV
F-----MDMTLTNKAMQPMTNFAIQLNKNSF--GLSPASPL-------------------
-----Q-AVPLPPNQSAEVSLALGTNGPIQR-----------MEPLNNLQ----------
----------------------VAV-KNNIDIFYFACLVHGNVLFAEDGQL---------
---DKRVFLNTWKEIPAANELQYSLSGVI-GTT----DGIASKMTTNNIFTIAKRNVEGQ
DMLYQ--SLRLTNNIWVLLELKLQPGNPDAT---LS----------LKS----------R
S-------VEVANII-------FAAYEAIIRSP
>gi|19112066|ref|NP_595274.1|	Schizosaccharomyces pombe
-----------------------MVPKLFQSSRFKAFKK----SETS--------ELQKG
LVSQYAYERIDAVKRTIAAMTVGKDVSSLFPDVLKNLATRDITLKKLVYLYLINYAKTHP
DLCILAVNTFVKDSEEYNPTLRALAIRTMGCIRVNKIIGYLADPLRKALKDEHPYVRKAA
AVCVVKMYDLDREYCASNGFIEQLQALVSDPNPV--------------------------
VVANAVRSLAEIHDQD---------------------PEKG--YFNVVYTMTDRLMVALS
ECNEWGRITILNSLARF----------RTSDIKEAEYVC-------ERVVPQFQ-HANSG
VVLSAVKVIM--VHIPLF---SSDFTDFLYKKMAP----PLLTLLSTD-SEIQYVALRNI
NLILQKR-----------PSIFDVKTRVFFCKYNDPLYIKMEKLKIITMLACDENINE--
-TISELRAYVSEVELEFVKQTIKCLGDVALKV--PSVIN---------DCISIFLEIYEL
NIS-YMVQEVTVVMETVLRKYPQKID---LLLPYLSRVIEELGDPR-------ARSSMAW
ILGEFSHVIPT-SSKLLSEMISTMADEDLQ---------------------IQLALLTAV
VKLSLMNGK------GNDEELVQKVLNYAINQSSNQDLRDRAFAYQRLLT-PEN-----V
RKAQK--IV-CCEKPSVSYNNN-LPEA--LLDALLCEITTLASVYHKLPESFIGQGKFGA
DAIQRRAVEELN-------IEEANVHEAIEK--------------------GANVENLLD
LDFTDPGATSAS-----------------D--------SPI-------------------
-----------------------------------TSAQPQSGSNSAMDLF---------
-------MAFEAPSTN--------------------------------------------
---------------------------------NAEP-----------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
----------------------------------------------VKA----------R
S-----------------------ATDDLLGL-
>gi|83766141|dbj|BAE56284.1|	Aspergillus oryzae
-----------------------MAMSRIRGA-FAVPRK----GETF--------ELRAG
LVSQYAYERKEAIQKTIMAMTLGKDVSALFPDVLKNIATSDLEQKKLVYLYLMNYAKSHP
DLCILAVNTFVQDSEDPNPLIRALAIRTMGCIRVDKMVDYMEEPLRKTLRDESPYVRKTA
AICVAKLFDLNPGMCMENGFLEMLQEMIGDPNPM--------------------------
VVANSVTALSEIHHAA---------------------PETN--ALQVTTNTLRKLLMALN
ECTEWGRVTILTTLAEY----------RTTEVTESEHIC-------ERVAPQFQ-HANPS
VVLAAVKVVF--LHMRNI---KDELSKNYLKKMAP----PLVTLVSSA-PEVQYVALRNI
DLLLQKQ-----------PDILNKELRVFFCKYNDPPYVKFQKLEIMVRIANDRNVDQ--
-LLAELKEYALEVDMDFVRRAVKAIGQVAIKI--ENASE---------KCVNTLLDLINT
KVN-YVVQEAIVVIKDIFRKYPG-YE---GIIPTLCKCIDELDEPN-------ARAALIW
IVGEYAEKINN-AGDILAGFVEGFNEEFSQ---------------------TQLQILTAV
VKLFVKRP-------EKAQGLVQKVLQAATAENDNPDVRDRAYVYWRLLSNTSD-----P
GATKN--IM-LSEKPPIVTTIHSLPPA--LLEKLLTELSTLASVYHKPPEQFVGQGRFGA
DAVQRAAIEEQI-------QNARENPLAAAAAAAAVSGKA-PPPQS-----QNNVENLLD
IDFDGGAPASAQKEPSAGMSGL-------EGLAG----TPV-------------------
---------------------RVESPAAGA-----PAGN-----NNLDDLLGVFGDGGGA
A------APVPAP------------------------------------------NGGSA
S--------------ADLMNGFA----------GLDLSSNT-------------------
-----T------------------------------------SPP---------------
------------------------------------------------------------
------------------------------------------------------------
------------------------PGGSQPK-----------------------------
-----------------------KTNEDILSLF
>gi|126324905|ref|XP_001364779.	Monodelphis domestica
-----------------------MTDSKY----FTTTKK----GEIF--------ELKAE
LNSDKKEKKKEAVKKVIASMTVGKDVSALFPDVVNCMQTDNLELKKLVYLYLMNYAKSQP
DMAIMAVNTFVKDCEDPNPLIRALAVRTMGCIRVDKITEYLCEPLRKCLKDEDPYVRKTA
AVCVAKLHDINAQLVEDQGFLDTLKDLISDSNPM--------------------------
VVANAVAALSEIAESH---------------------PSSN--LLDLNPQSINKLLTALN
ECTEWGQIFILDCLANY----------MPKDDREAQSIC-------ERVTPRLS-HANSA
VVLSAVKVLM--KFMEML-SKDLDYYGTLLKKLAP----PLVTLLSAE-PELQYVALRNI
NLIVQKR-----------PEILKHEMKVFFVKYNDPIYVKLEKLDIMIRLASQANIAQ--
-VLAELKEYATEVDVDFVRKAVRAIGRCAIKV--EQSAE---------RCVSTLLDLIQT
KVN-YVVQEAIVVIKDIFRKYPNKYE---SVIATLCENLDSLDEPE-------ARAAMIW
IVGEYAERIDN-ADELLESFLEGFHDESTQ---------------------VQLQLLTAI
VKLFLKKP-------TETQELVQQVLSLATQDSDNPDLRDRGYIYWRLLS--TD-----P
VAAKE--VV-LAEKPLISEETDLIEPT--LLDELICYIGTLASVYHKPPSAFVE----GS
RGVVHKSLPPRTGS-----SESAESPEAAPTGAPPSEQPA-VIPAQ-----GDLLGDLLN
LDLGPPVSGPPMTTASVQMGAV-------DLLGGGLD-SLLLGSFLSLQPRGDVSGSPAV
ST-------------------NFAAPPAGTM----PATLSAPIGGGLGDLFDLTSGVGTL
S------GSYVAPKAV---------------------WLPAMKAKGLEISGTFTRQVGSI
S-----MDLLLTNKALQVMSDFAIQFNRNSF--GLAPAAPL-------------------
-----QVHAPLSPNQTVEISLPLNTVGSVMK-----------MDPLNNLQ----------
----------------------VAV-KNNIDVFYFSTLYPLHILFVEDGKM---------
---ERQMFLATWKDIPNENEAQFQIKDCP-LNA----EAVSSKLQGSNIFTIAKRNVEGQ
DMLYQ--SLKLTNGIWVLAELRIQPGNPNFT---LS----------LKC----------R
A-------PEVSQHV-------YQAYETVLKN-
>gi|47221396|emb|CAF97314.1|	Tetraodon nigroviridis
-----------------------MTDSKY----FTTNKK----GEIF--------ELKAE
LNNEKKEKRKEAVKKVIAAMTVGKDVSSLFPDVVNCMQTDNLELKKLVYLYLMNYAKSQP
DMAIMAVNSF--DCEDPNPLIRALAVRTMGCIRVDKITEYLCEPLRKCLKDEDPYVRKTA
AVCVAKLHDINAQMVEDQGFLDSLRDLIADSNPMVGEWTSPIGSVGSRSVFAHDATPVSQ
VVANAVAALSEISESH---------------------PNSN--LLDLNPQNINKLLTALN
ECTEWGQIFILDCLSNY----------NPKDDREAQSIC-------ERVTPRLS-HANSA
VVLSAVKVLM--KFLELL-PKDSDYYNTLLKKLSP----PLVTLLSGE-PEVQYVALRNI
NLIVQKR-----------PEILKQEIKVFFVKYNDPIYVKLEKLDIMIRLASQANIAQ--
-VLAELKEYATEVDVDFVRKAVRAIGRCAIKV--EQSAE---------RCVSTLLDLIQT
KVN-YVVQEAIVVIRDIFRKYPNKYE---SIIATLCENLDSLDEPD-------ARAAMIW
IVGEYAERIDN-ADELLESFLEGFHDESTQ---------------------VQLTLLTAI
VKLFLKKP-------SETQELVQQVLSLATQDSDNPDLRDRGYIYWRLLS--TD-----P
VTAKE--VV-LSEKPLISEETDLIEPT--LLDELICHIGSLASVYHKPPSAFVE----GS
HGIHRKHLPVQHSS-----IDTGESP-VSSAPAAAIDQHH-VIPSQ-----GDLLGDLLN
LDLGPPVNVPQV--SSMQMGAV-------DLLGGGLD-SLL-----GGDLGGGVGGSPAV
GQ-------------------NFIPSSVPSTFAPSPTPAPPAASSGLNDLFELSTGMAIS
T------GGYVPPKAV---------------------WLPAVKAKGLEISGTFSRRQGHM
Y-----MDMSFTNKALQHMTDFAVQFNKNSF--GMIPTSPL-------------------
-----PIHTPLMPNQSIEVSLPLNTIGPVMK-----------MDPLNNLQ----------
----------------------VAV-KNNIDVFYFSVLIPLNIFFVEDGKMVHQWRLDVF
VASERQVFLATWKDIPNENELQYQIKDCH-LNA----DTVSGKLQNNNIYTIAKRNVEGQ
DMLYQ--SLKLTNGIWILAELRIQPGNPNYT---LS----------LKC----------R
A-------PEVSQYI-------YQMYDSVLKN-
>gi|6322714|ref|NP_012787.1|	Saccharomyces cerevisiae
------------------MPPLDKRIKKFLKDSIRIAPKISGKGELS--------ELRTG
LVSQYPQTRKDAIKKTIQQMTLGKDVSSLFPDVLKNIATIDVEQKKLVYLYVMNYAETHP
ELCILAVNTFITDAQDPNPLIRCMAIRTMSMIRVDKILEYIETPLRRTLHDDNAYVRKTA
VICVAKLFQLNKDLCVELGVVEDLVNALDDSNPL--------------------------
VIANATAALIEIHNMD---------------------MDAV-DLSSLIQSHVSQFLLALN
ECTEWARIIILGTLSEY----------SAKDSLEAQDII-------DRVTAHLQ-HVNPA
VVLATIKVIV--RNLPQI---EYSSNSLIMKRLSS----AFVSLMSTP-PEMQYVALKNI
RIILEKY-----------PELLTKELRIFYVKFNDPLYVKLEKIDILVRLVDPSNLKQCT
LLLTELKEYAMEYEPEFVSRAIQALSQLGIKYAQESFVS---------KVLDILLELLER
QD--TIKDDCCISLCDLLRHCPGNDK----MAKQVCAVFNTWSNPEVLLQSDIAKCNYVW
LLGQHPNNFSD-LESKINIFIENFVQEEAL---------------------TQMSLLMTI
VRLHA----------TLTGSMLQSVLELATQQTHELDVRDMAMMYWRCLSMPNN-----E
SLVND--LC-QNKLPMISNTLEKFSPE--VLEKLLMELGTISSIYFKPDSNRRKGKKYVQ
NIVKGKHIEELE----------------------SMAKNE-ISSKA-----NDDV--LLD
FDERDDV-------TNTNAGML-------NTL------TTL-------------------
--------------------------------------------GDLDDLFDFG------
---------------------------------------PSEDATQINTNDT--------
-------------KAVQGLKELKLGGDSN----GISSGGKN-------------------
-----N------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
--------PDVSGG--------NIVSQDLLDLF
