>gi|149705462|ref|XP_001491579.	Equus caballus
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------MGNPENTEDAYVAVIRPKN------TASLN
SREYRAKSYEILLHEVPIEGQKKK---RKKVLL---ETKLQGSSEITQGILDYVVETTKP
ISPANQGIRGKRVVLMKKFPLDGEKMGREAALFIVPS-----------VVKDNTKYTYTP
GCPIFYCLQ---------------DIMRVCSESSTHFATLTARMLIALD-------KWLD
ERHAQSHFIPALFRP--------SPLERIKTN----------------------------
--------------------VINPAYAT-ESGQTENSLHMGYSALEIKSKMLALEKADTC
IYNPLFGSDLQYTNRVDKVVINPYFGLGA---------------PDYSKIQIPKQ-----
----EKWQRSMSSVTEDKERQWVDDFPLHRSACEGDSELLSRLLNERFSVNQLDSDHW--
-------------------------------APIHYACWYGKVEATRILLEKGKCNPNLL
NGQLSSPLHFAAGGGHAE-IVQILLNHPEVDR----------------------------
---------HITDQQGRSPLNICEENKQNNWEEAAKLLKEAINKP---------------
-----------------------YEKVRIYRMDGSYRSVELKHGNNTTVQQIME-GMRLS
QETQQ-----YFTIWICSENLSLQLKPYHKPLQHVRDWPEILAELTNLDPQRETPQLFLR
RDVRLPLEVEKKIEDPLAILILFDEARYNLLKGFYTAPDAKLITLASLLLQIVYGNYESK
KHKQGFL----NEENLKSIVPVTKLKSKAPHWTNRILHEYKNLSTSEGVSKEMHHLQRMF
LQNCWEIPTYGAAFFTGQIFTKAS----PSNHKVIPVYVGVNIKGLHLLNMETK------
------------------------ALLLSLKYGCFMWQLGDADTCFQIHSM---------
--ENKMSFIVHTKQAGL-----VIKLLIKLNGQLMPT-----------------------
------------------------
>gi|67970278|dbj|BAE01482.1|	Macaca fascicularis
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
--------------MWFSPRSKKV---RYVVSKVSVRTQLEIKKDANGQQDSYEFVSTSP
PADVSERAKKASARSRKKQKKKTLAEINQKWNLEAEK-----------EDGEFDSKEESK
QKLVSFCSQ---------------PSV----ISSPQINGEIDLLASG------------S
LTESECFGSLTEVSL-PLAEQIESPDTKSRNE----------------------------
--------------------VVTPEKV--CKNYLTSKKSWPLENNGKRGHHNRLSS--PI
SKRCRTS-------------ILSTSGDFV--KQTMP-----SENTPLPECSSPP------
----SCKRKVGGTSGRKKSNLSDEFISLSPGTPPST--LNSSSYRRVMFSPSAM------
----------------KLLPNMAVKRNHRGETLLHIASIKGDIPSVEYLLQNG-SDPNVK
DHAGWTPLHEACSHGHLK-VVELLLQHKALV-----------------------------
---------NTTGYQNDSPLHDAAKNGH---MDIVKLLLSYGASR---------------
------------------------NAVNIFGLRPVDYTD--DENMKSL--LLLPEKNESS
TTSHCS---VMNIGQRRDGPLVLIGSGLSSEQQKTLSELAAILKAKKCTEFDSTVTHVVV
PGDAVQ----STLKCMLGILN----GCWILKFEWVKACLRRRVCEQEEKYEIPEGPHRSR
LNREQLL--------PKLFDGCYFYLGGSFK-HHPKDNLIKLVTAGGGQILSRKP-----
---------KPDSDVTQTINTVAYHARPDSDQRFCTQYIIY--EDLSNYHPER-------
-----------------------------VRQGK-VWKAPSSWFIDCVM-----------
----------------------SFELLPLDS-----------------------------
------------------------
>gi|157106389|ref|XP_001649301.	Aedes aegypti
------TPLHTAAGKGNIEMVKLLIDHNANIDTKD------------------------D
EGCTPLHYASRNGNLEMVKLLIDNRANVDTTQN---------------------------
-----------------EGW--------------------------------TPLHYASQ
NGHIDVVKLLIDNRA---------NVDTTQNEGCTPLHKAAENGHLDVVKLLID-NKANV
DTAQSEGWTPLHYASRNGNLEL-V---KLLIDN---RANVDTAQYEGWTPLHYASRNGQL
DVVKLLIDNRANVDTTQNEGCTPLHYASQNGNLELVK----LL----IDNRANVDTAQYE
GWTPLHYAS-----------------------QNGQLDVVKLLIDNRANVDTTQNEGCTP
LHYASRNGNLELVKLLIDNRANVDTAQYEGWT----------------------------
--------------------PLHYAS---RNGQLDVVKLLIDNRANVDTTQNEGCT--PL
HYASRNG-------NLELVKLLIDNRANV-DTAQYE--GWTPLHYASQNGQL--------
----DVVKLLIDNRANVDTTQNEGCTPLHYASRNGNLELVKLLIDNRANVDTAQYEGWTP
LHY-------------ASRNANVDTTQNEGCTPLHYASRNGNLELVKLLIENR-ANVDTA
QNEGWTPLHYSSQNGHLK-VVKLLIENKANV-----------------------------
---------DTTQNEGWTPLHYAFQNGH---LEVVKFLIDNGANV---------------
------------------------DTMNTRGSTSFHIVS--QNGRLVLVKLLIDNRANVD
TTDNEGWTPLHYASQNGHLEVVKFLIDNGANFDTKNTRGSTSFHIASKNGRLEVVKLLID
NGANVD---TTNNEGWTPLHYASRNGHLEVVKLLIDNGANVDTKNARGSTSFHIVSQNGR
LEVVKLLIDNRANVDTTDNEGWTPLHYAS---RNGHLEVVKLLIDNGANVDTKNTRGSTS
FHIAS---KNGRLEVVKLLIDNGANVDTTNNEGWTPLHYAS--RNGHLEVVKLL------
-----------------------------IDNGA-NVDTKNARGSTSFHIV---------
-----------SQNGRLE----VVKLLIDNGANVDTTYNERWTLLHDASLNGHLEVVKLS
ID----------------------
>gi|18129624|ref|NP_076152.2|	Mus musculus
-----------MEGEG---------------RGRW------------------------A
LGLLRTFDA---------------------GEF---------------------------
-----------------AGW------------E-KVG----------S-GGFGQVYKVR-
HVHWKTWLAIKCSPS---LHVDD-RERMELLEEAKKMEMAKFRYILPVYGICQE-PVGLV
MEYMETGSLEKLLASEPLPWDLRF---RIVHET---AVGMNFLHCMSPPLLHLDLKPANI
LLDAHYHVKISDFGLAKCNGMSHSHDLSMDGLFGTIA----YL----PPERIREKSRLFD
TKHDVYSFA---------------IVIWGVLTQKKPFADEKNILHIMMKVVKGHRPELPP
ICRPRPRACASLIGL-MQRCWHADPQVRPTFQ----------------------------
--------------------EITSETEDLCEKPDEEVKDLA-HEPGEKSSLESKSEARPE
SSRLKRASAPPFDNDCSLSELLSQLDSGI--SQTLE--GPEELSRSSSECKLPSS-----
----SSGKRLSGVSSVDSAFSSRGSLSLSFEREASTGDLGPTDIQKKKLVDAIISGDTSR
LMK-------------ILQPQDVDLVLDSSASLLHLAVEAGQEECVKWLLLNN-ANPNLT
NRKGSTPLHMAVERKGRG-IVELLLARKTSV-----------------------------
---------NAKDEDQWTALHFAAQNGD---EASTRLLLEKNASV---------------
------------------------NEVDFEGRTPMHVAC--QHGQENIVRTLLRRGVDVG
LQGKDAWLPLHYAAWQGHLPIVKLLAK--------------------------------Q
PGVSVN---AQTLDGRTPLHLAAQRGHYRVARILIDLCSDVNICSLQAQTPLHVAAETGH
TSTARLLLHRGAGKEALTSEGYTALHLAA---QNGHLATVKLLIEEKADVMARGPLNQTA
LHLAA---ARGHSEVVEELVSADL-IDLSDEQGLSALHLAA--QGRHSQTVETL------
-----------------------------LKHGA-HINLQSLKFQGGQSS----------
----------------------AATLLRRSKT----------------------------
------------------------
>gi|109493006|ref|XP_221619.4|	Rattus norvegicus
-----------MEGEG---------------RGRW------------------------A
LGLLRTFDA---------------------GEF---------------------------
-----------------AGW------------E-KVG----------S-GGFGQVYKVR-
HVHWKTWLAIKCSPS---LHVDD-RERTELLEEAKKMEMAKFRYILPVYGICQE-PVGLV
MEYMETGSLEKLLASEPLPWDLRF---RIVHET---AVGMNFLHCMSPPLLHLDLKPANI
LLDAHYHVKISDFGLAKCNGMSHSHDLSMDGLFGTIA----YL----PPERIREKSRLFD
TKHDVYSFA---------------IVIWGVLTQKKPFSDEKNILHIMMKVVKGHRPELPP
ICRPRPRACASLIGL-MQRCWHADPQVRPTFQ----------------------------
--------------------EITSETEDLCEKPDEEVKDLA-HEPGEKSSPEPRSEARPE
SSRLKRASAPPFDNDCSLSELLSQLDSGI--SQTLE--GPEELSRSSSECKLPSS-----
----SSGKRLSGVSSVDSAFSSRGSLSLSFEREASTGDLGPTDIQKKKLVDAIVSGDTNK
LMK-------------ILQPQDVDLVLDSSASLLHLAVEAGQEECVKWLLLNN-ANPNLT
NKKGSTPLHMAVERRGRG-IVELLLARKTSV-----------------------------
---------NAKDEDQWTALHFAAQNGD---EASTRLLLEKNASV---------------
------------------------NEVDFEGRTPMHVAC--QHGQENIVRTLLRRGVDVG
LQGKDAWLPLHYAAWQGHLPIVKLLAK--------------------------------Q
PGVSVN---AQTLDGRTPLHLAAQRGHYRVARILIDLSSDINICSLQAQTPLHVAAETGH
TSTARLLLHRGAGKEALTSEGYTALHLAA---RNGHLATVKLLIEEKADVLARGPLNQTA
LHLAA---ARGHSEVVEELVSADL-IDLSDEQGLSALHLAA--QGRHSQTVEIL------
-----------------------------LKHGA-HINLQSLKFQGGQSS----------
----------------------TATLLRRSKT----------------------------
------------------------
>gi|70982929|ref|XP_746992.1|	Aspergillus fumigatus
---------MTISNTGHDLN---------------------------------------R
ICLVLDEII---------------------------------------------------
-----------------PTW-----------------------------KAHSSILMTHP
SASFGMWPCVQCNLENIRVTLQQLRQELEPVAESGQKKRSLFKVYAKAWKLGLH-SRAII
AYRGRLEPHRKALRVGATMMNMCV---RLQLNA--------SAQEKQSFLVVLDMEIKDL
EAAVQ-SLKKLSFVSSGEIAERQNMIVAMEGLISSAKSFYTFMSVAPSAPTVNQEDGHGS
APPPSYAQAMAPDDGAESEDSAPWPSPFNVAAREGNLEEIKRLVAAGEDILATGEIGQSP
AYSAAVSGNTEILEYLIEHGADYTSGNENGFT----------------------------
--------------------PLNAAA---TFGHPDAVLALLHHGADPNVPSVDGQS--PI
YSAAKLG-------QLGSVKVLVEHGVNI--SDTTHPKQWTPLNVAANSGHL--------
----HIVKYLLDQGADFNLPTTSGWTPLASAASEGHAEIVETLIKRGADVNAII------
--------------------------GEVGATPLYCAAKDGHTDVVRILLDHG-ADTSQA
SANKWTPLNAAASEGHLA-VVELLLAKGADV-----------------------------
---------TTPDRTGWAPLNSAAAAGH---FEIAVALVKHGADH---------------
------------------------AVADSRGHTPLYSAA--LHGHHAIVDLLLEAGASIN
VTNKDKWTPLHAASARGHLQVVQSLIACGANSATRNMDGWSPLNSAACNGHLEVVKLLLR
HGAAVD---SRSDDGWSPLTAAAGNGHTAVVEALLDRKTDIETRNDIGWTSLGIAAREGY
PETVKVLLARGADKNATNINGWTALHGAV---EKDQLEVVTLLLAQGLDISAKSNTGWTP
LNIAA---SNGRATIAQFLLASGADPNTPQDDGWTPLHVAT--NENHIEVVRAL------
-----------------------------LRAGA-DCHAKNQNGKTALDLA---------
-----------RSKGYTV----MEELLLGAG------------------------VKRLG
FE----------------------
>gi|109065252|ref|XP_001107026.	Macaca mulatta
-----------MEGDG---------------GTPW------------------------A
LGLLRTFDA---------------------GEF---------------------------
-----------------TGW------------E-KVG----------S-GGFGQVYKVR-
HVHWKTWLAIKCSPS---LHVDD-RERMELLEEAKKMEMAKFRYILPVYGICRE-PVGLV
MEYMETGSLEKLLASEPLPWDLRF---RIIHET---AVGMNFLHCMAPPLLHLDLKPANI
LLDAHYHVKISDFGLAKCNGLSHSHDLSMDGLFGTIA----YL----PPERIREKSRLFD
TKHDVYSFA---------------IVIWGVLTQKKPFADEKNILHIMVKVVKGHRPELPP
VCRARPRACSHLIRL-MQRCWQGDPRVRPTFQ----------------------------
--------------------EITSETEDLCEKPDDEVKETT-HDLDVKSPPEPRSEVVPV
SARLKRASAPTFDNDYSLSELLSQLDSGV--SQAVE--GPEELSRSSSESKLPSS-----
----GSGKRLSGVSSVDSAFSSRGSLSLSFEREPSTSDLGTTDVQKKKLMDAIVSGDTSK
LMK-------------ILQPQDVDLALDGGASLLHLAVEAGQEECVKWLLLNN-ANPNLT
NRRGSTPLHMAVERKVRG-VVELLLARKISV-----------------------------
---------NAKDEDQWTALHFAAQNGD---ESSTRLLLEKNASV---------------
------------------------NEVDFEGRTPMHVAC--QHGQENIVRILLRRGVDVS
LQGKDAWLPLHYAAWQGHLPIVKLLAK--------------------------------Q
PGVSVN---AQTLDGRTPLHLAAQRGHYRVARILIDLCSDVNVCSLLAQTPLHVAAETGH
TSTARLLLHRGAGKEAVTSDGYTALHLAA---RNGHLATVKLLIEEKADVLARGPLNQTA
LHLAA---AHGHSEVVEELVSTDV-IDLFDEQGLSALHLAA--QGRHAQTVETL------
-----------------------------LRHGA-HINLQSLKFQGGHGP----------
----------------------TATLLQRSKT----------------------------
------------------------
>gi|91092618|ref|XP_967612.1|	Tribolium castaneum
------MCPLVVEGHV-------------------------------------------K
MSALDLVED---------------------------------------------------
----------------------------------------------------GNIVILNP
KFNVSSLKCLKDKKNVCFQNLGDLENYKEVYDNMLDTYQYSIEGQEKANLRSLVSNGCVR
AEHFTTDALLEMSTNKGVNADIQDNDGKVPIHYACESENVDVVKLLLDKGVNADIQDNDG
KVPIHYAYKGVNADIQDNDGKVPIHYACESENVDVVK----LL----LDKGVNADIQDND
GKVPIHYAY------------------------------------KGVNADIQDNDGKVP
IHYACESENVDVVKLLLDKGVNADIQDNDGKV----------------------------
--------------------PIHYAY---KG-------------VNADIQDNDGKV--PI
HYACESE-------NVDVVKLLLDKGVNA-DIQDND--GKVPIHYAYNDGKVPIHYACGW
FMNGNIVKLLLDKGVNADIPDNNGKLPIHYACERGNVDVVKLLLDKGVNVVIADNNGKLP
IHY-------------AYKGVNADIPDNNGKLPIHYACERGNVDVVKLLLDKG-VNVVIA
DNNGKLPIHYACGWFMNGNIVKLLLDKGVNA-----------------------------
---------DIQDNDGKLPIHYACARGN---VGVVKLLLDKGVNA---------------
------------------------DIQDNDGKVPIHYACG-WFMNGNIVKLLLDKGVNAD
IPDNNGKLPIHYACENGNVDVVKLLLDKGVNADIQDNDGKLPIHYACARGNVGVVKLLLD
KGVNAD---IQDNDGKVPIHYACESGNVDVVKLLLDKGVNVVIADNNGKLPIHYACERGN
VDVVKLLLDKGVNADIQDNDGKVPIHYACGWFMNG--DIVKLLLDKGVNADIQDNDGKVP
IHYACGWFMNG--NIVKLLLDKGVNADIPDNNGKLPIHYAC--ENGNVDVVKLL------
-----------------------------LDKGV-NADIQDNDGKLPIHYA---------
-----------CARGNVG----VVKLLLDKGVNADIQDNDGKVPIHYACESGNVDVVKLL
LDKGVNVVIADNNGQLPIHYACGC
>gi|147899426|ref|NP_001082131.	Xenopus laevis
--------MLLRVRSG------------NRPSETA------------------------V
REELPMMDE---------------------------------------------------
-----------------PGWERTRDALREMERKLCCSKCMFILKDPVCLGGCEHVFCWTC
VNENLGNECPLCNTPAWVRDVQVNRQLDNMIQLCAKLRNLLSMGKTDENKMDLCQDTLLR
LNPAQEKQKKKQIKMWFSPRSRKV---RCVVEKK--EKSQQISSKTLPQMASYEFVSDSP
--DGEPAQKKPDPKPRKRMKKK-LKDINAEWGVDTEN-----E----IDEVSNPRKEHKS
GKSVSFCSS---------------AVI-------------------------QHSPEVLV
VESSLKNDTPEEISPNWNKCGLDEPMEMQSTS----------------------------
-----------------MKEVNCPSPSEQSTTLKTQDKEKKITTVKRKKHSSPIAS----
SKRPRRR-------SSDTSKPLNDSDIKA--------NSPEKACKTVSPHKPSEN-----
----SAKDVRIESTQAAKRDTKMCSTPLPCAKQNNSAKLGQKSTAMPISPNNLTNVKR--
--------------------------NYKGETMLHLASIKGDIQGVEDLLNSG-ANPNVK
DNAGWTPLHEACNLGHTM-VVQLLLQHHALM-----------------------------
---------NTTGYQNDTPLHDAVKNGH---IAIVKLLLSHGASR---------------
------------------------DAVNIFGLQPVDYAE--TEEMKSVL-LETQTERDRL
LLHPCLAAPQLSSHQRKEEAVVLIASGLLATQRADLTKLAKMLKASICAEYDSTVTHVIV
SDEPVL----RTMKCMMGILA----GCWTLQFSWVKACLQSCNREPEESYEIPHGPHRAR
LNGQQML--------PQLLDGCHFYFLGCFT-EHRKEDLIELVKAAGGQILIRQP-----
---------KPDSDVTQTINTVAYHAEADSDQRFCTQYIVF--DRASKYRPER-------
-----------------------------VRQGK-VWFAPSSWIIECIT-----------
----------------------SFQLLPVH------------------------------
------------------------
>gi|47564094|ref|NP_001001166.1	Bos taurus
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------MGNPENIEDAYVAVIRPKN------AASLN
SREYRAKSYEILLHEVPIEGQKKK---RKKVLL---ETKLQGNSEITQGISDYVVETTEP
ISPANQGIRGKRVVLMKTFPLEGEKVGREAALFIVPS-----------VVKDNTKYTYTP
GCPIFYCLQ---------------DIMRVCSESSTHFATLTARMLIALD-------KWLD
ERHTQSHFIPALFRP--------SPLERIKTN----------------------------
--------------------VINPAYAT-ESGQAENSLHMGYSALEIKSKMLALEKADTC
IYNPLFGSDLQYTNRVDKVVINPYFGLGA---------------PDYSKIQIPKQ-----
----EQWQRSRSSVTEDKERQWVDDFPLHRSACEGDSELLNRLLNERFSVNQLDSDHW--
-------------------------------APIHYACWYGKVEATRILLEKGKCNPNLL
NGQLSSPLHFAAGGGHAE-IVQILLNHPEIDR----------------------------
---------HITDQQGRSPLNICEENKQNNWEEAAKLLKEAINKP---------------
-----------------------YEKVRIYRMDGSYRSVELKHGNNTTVQQIME-GMRLS
QETQQ-----YFTIWICSENLSLQLKPYHKPLQHVRDWPEILAELTNLDPQRETPQLFLR
RDVRLPLEVEKKIEDPLAILILFDEARYNLLKGFYTAPDAKLITLASLLLQIVYGNYESK
KHKQGFL----NEENLKSIVPITKLKSKAPHWTNRILHEYKNLSTSEGVSKEMHHLQRMF
LQNCWEIPTYGAAFFTGQIFTKAS----PSNHKVIPVYVGVNIKGLHLLNMETK------
------------------------ALLISLKYGCFMWQLGDADSCFQIHSM---------
--ENKMSFIVHTKQAGL-----VVKLLVKLNGQLMPMERNS-------------------
------------------------
>gi|118083928|ref|XP_416738.2|	Gallus gallus
-----------MARES---------------GSPW------------------------A
MGLLKTFEE---------------------SEF---------------------------
-----------------GSW------------E-KIG----------S-GGFGQVYKVR-
HLHWKTWLAIKCSPS---LHVDE-KERMELLEEARKMEMAKFRYILPVYGICKE-PVGLV
MEYMETGSLEKLLASEPLPWELRF---RIIHET---AVGMNFLHCMSPPLLHLDLKPANI
LLDAHYHVKISDFGLAKCNGLSHSHDLSMDGLCGTIA----YL----PPERIKEKNRCFD
TKHDVYSFS---------------IVIWGVLTQKKPFAEENNILHIMVKVVKGHRPELPA
VSKSRPHSCNNLIKL-MQKCWQDDPGERPTFQ----------------------------
--------------------EITSVTETLCEKPEDETKEMVAEDLDTKSSPKQRSE--VF
CLSPKQEPVLASDKDYSLSELLSQLDSGI--SQTME--GPEDLSRSSSESKLA-------
----ASDKRLSGVSSVDSAFSSRGSLSLSFERESSGNDIGTTDIQKRKLTEAILAGDTSK
LMK-------------ILQPQDVDIVLDGNSSLLHLAVEAGQEECVKWLLLYN-ANPNLT
NKKGSTPLHIAIEKKIKS-IVELLMARKINV-----------------------------
---------NAKDEDQWTALHFAAQNGD---DFSTKMLLDKNASL---------------
------------------------NEVDFEGRAPIHIAC--QYGQENIVRILLRRGVNVN
IKGKDDWVPLHYAAWQGHLPIVKLLAK--------------------------------Q
PGANVN---VQTVDGRTSLHLAAQRGHYRVARLLIDLESDVNVLNALSQTALHIAAETGH
TSTSRLLLKHGADIEAVTVEGCTALHLAS---RSGHLATTKLLTDEGANVLARGPLNRTA
LHLAA---ENGHSEVVEELVSSGN-INVSDDEGLTAFHLAA--RGGHTKTVEVL------
-----------------------------LKHGA-LTDLQRPTFQTLLRL----------
-----------TQQSSNS----SVTVLLSET-----------------------------
------------------------
>gi|114583125|ref|XP_001149370.	Pan troglodytes
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-----------------------------MIQLCSKLRNLLHD--NELSDLKEDKPR--K
SLFNDAGNKKNSIKMWFSPRSKKV---RYVVSKASVQTQPAIKKDASAQQDSYEFVSPSP
PADVSERAKKASARSGKKQKKKTLAEINQKWNLEAEK-----------EDGEFDSKEESK
QKLVSFCSQ---------------PSV----ISSPQINGEIDLLASG------------S
LTESECFGSLTEVSL-PLAEQIESPDTKSRNE----------------------------
--------------------VVTPEKV--CKNYLTSKKSLPLENNGKRGHHSRLSS--PI
SKRCRTS-------------ILSTSGDFV--KQTVP-----SENIPLPECSSPP------
----SCKRKVGGTSGRKNSNMSDEFISLSPGTPPST--LSSSSYRRVMSSPSAV------
----------------KLLPNMAVKRNHRGETLLHIASIKGDIPSVEYLLQNG-SDPNVK
DHAGWTPLHEACNHGHLK-VVELLLQHKALV-----------------------------
---------NTTGYQNDSPLHDAAKNGH---VDIVKLLLSYGASR---------------
------------------------NAVNIFGLRPVDYTD--DESMKSL--LLLPEKNESS
SASHCS---VMNTGQRRDGPLVLIGSGLSSEQQKMLSELAAILKAKKYTEFDSTVTHVVV
PGDAVQ----STLKCMLGILN----GCWILKFEWVKACLRRKVCEQEEKYEIPEGPRRSR
LNREQLL--------PKLFDGCYFYLWGTFK-HHPKDNLIKLVTAGGGQILSRKP-----
---------KPDSDVTQTINTVAYHARPDSDQRFCTQYIIY--EALCNYHPER-------
-----------------------------VRQGK-VWKAPSSWFIDCVM-----------
----------------------SFELLPLDS-----------------------------
------------------------
>gi|74001471|ref|XP_544897.2|	Canis familiaris
MTVRAQLCTRLPERKGHATV--------CDPRPRS------------------------R
AGRLRARAAYGRVYSGRPCALEAAAHHRVLGQF---------------------------
-----------------AGW------------DDRSG----------ARAASGRCYKVPP
DVHWKTWLAIKCSPS---LHVDD-RERVELLEEAKKMEMAKFRYILPVYGICQE-PVGLV
MEYMETGSLEKLLASEPLPWDLRF---RIIHET---AVGMNFLHCMAPPLLHLDLKPANI
LLDAHYHVKISDFGLAKCNGLSHSHDLSMDGLFGTIA----YL----PPERIREKSRLFD
TKHDVYSFA---------------IVIWGVLTQKKPFADEKNILHIMVKVVKGHRPELPP
VCRARPRACGALLRL-MQRCWHGDPRERPTFQ----------------------------
--------------------EITCETEDLCEKPDSDVKETA-QDLDTKQPPEPKSP--PV
CTPLKRASAPTFDSDYSLSELLSQLDSGT--SQTLD--GPEELSRSCSESRLPSA-----
----SSGKRLSGVSSVDSAFSSRGSLSLSFEREPSTGDLGTTDIQKKKLVDAIVSGDTSR
LMK-------------ILQPQDVDLVLDGGASLLHLAVEAGQEECVKWLLLNN-ANPNLT
NRKGSTPLHVAVEKRVRG-VVELLLARKISV-----------------------------
---------NAADEDQWTALHFAAQNGD---ECSTRLLLEKHASV---------------
------------------------SEVDCEGRTPMHVAC--QHGQEGIVRILLRRGVDVS
LRGKDAWVPLHYAAWQGHLPIVRLLAK--------------------------------Q
PGVSVN---AQTLDGRTPLHLAAQRGHYRVARVLIDLRSDVNVCSLLSQTPLHVAAETGH
TSTARLLLHRGADKEAVTAEGYTALHLAS---RNGHLATVKLLVEEKADVLARGPRNQTA
LHLAA---ARGHSEVVEELVSADA-LDLSDEQGLSALHLAA--QGKHTKTVETL------
-----------------------------LKHGA-HVNLQSLKFQGGRSP----------
----------------------DAALLRRSKT----------------------------
------------------------
>gi|115939150|ref|XP_001196293.	Strongylocentrotus purpuratus
-MENINKQLHEAALRGEIKSVQKLLKQGSNINQKD------------------------R
HGNTPLHMAVQ---NGHENVLEYLINHGADVEK---------------------------
-----------------TTA-----------------------------GGHTPLHL---
AASLGRLKATKCLLS----------HGANVSREDKDSFCALYSAVW---------NGAEV
NEGENDGRTALHLAAHKGHLDVT----KYLIMQ---GAEVNRGDNVGVTALQLAAQNGHL
HITKYLNIQGAELNKGENVGVTALHRSAKNGHLEVTK----NL----RSQGAEMNEGEND
GW-TSLHFA----------------------AFSGDLHVTNDLISQGAEVNNGNNGGWTA
LHIAANNGHLDVTKYLITEGAEVNKGNNGGWT----------------------------
--------------------ALFSAA---QNGHLDVTKYLISQGAKMNERDDKGWT--PL
HNAAFIG-------HLDVTRYLISQGAEMIREDAVDNGGWTALHIAAQNGHR--------
----DVAIYLTSHGAEVNTGNNDGFTALHSAAFSCKLDVTEYLISQGAELNKGDNVGVTA
LHHSAQNGHLDITKYLISQGAEVKKRDNEGRTALHIAVQNGHLDVTEYLISQG-AEVNKR
DNKGRTALRSAAFYGQLH-VSKYLISQASEL-----------------------------
---------NKVNNDGSTALHSAAKYGH---LDVLRLCISRGAKV---------------
------------------------NQCNTKGRTPLSIAT--MHGNLDVVKYLVSVG-EVN
KGDTDGWTALHGASQNGHLDVTRYLISQGAQMNKGNNDGRTALHIASHKGHLDVTKYLIS
RGAEVN---KEDNNGRPPLHGAAQNGHLDVTEYLISQKAEEN---NGAWTALQVAAHNGH
LDVTKFLISQGAEVNKGNNDGRTALHSAV---QNGSIDVVKYLLAAGARVDTSDIHGQTP
LQLSF---ILGFENIADVFIDSSK--SKLDQNDLKAIHLAI--QHGHTSIIEKL------
-----------------------------VSAGA-DLNIQSTDGQTCLHKAIKLCNKSEE
IMQGTDTLKDNSDEGELSPEKALVFYLLENGAKLDVKDKTGNLPIQYAKDE---EIKQMI
FSR---------------------
>gi|114684393|ref|XP_001134659.	Pan troglodytes
-----------MEGDG---------------GTPW------------------------A
LGLLRTFDA---------------------GEF---------------------------
-----------------TGW------------E-KVG----------S-GGFGQVYKVR-
HVHWKTWLAIKCSPS---LHVDD-RERMELLEEAKKMEMAKFRYILPVYGICRE-PVGLV
MEYMETGSLEKLLASEPLPWDLRF---RIIHET---AVGMNFLHCMAPPLLHLDLKPANI
LLDAHYHVKISDFGLAKCNGLSHSHDLSMDGLFGTIA----YL----PPERIREKSRLFD
TKHDVYSFA---------------IVIWGVLTQKKPFADEKNILHIMVKVVKGHRPELPP
VCRARPRACSHLIRL-MQRCWQGDPRVRPTFQ----------------------------
--------------------EITSETEDLCEKPDDEVKETA-HDLDVKSPPEPRSEVVPV
SARLKRASAPTFDNDYSLSELLSQLDSGV--SQAVE--GPEELSRSSSESKLPSS-----
----GSGKRLSGVSSVDSAFSSRGSLSLSFEREPSTSDLGTTDVQKKKLVDAIVSGDTSK
LMK-------------ILQPQDVDLALDSGASLLHLAVEAGQEECVKWLLLNN-ANPNLT
NRRGSTPLHMAVERRVRG-VVELLLARKISV-----------------------------
---------NAKDEDQWTALHFAAQNGD---ESSTRLLLEKNASV---------------
------------------------NEVDFEGRTPMHVAC--QHGQENIVRILLRRGVDVS
LQGKDAWLPLHYAAWQGHLPIVKLLAK--------------------------------Q
PGVTVN---AQTLDGRTPLHLAAQRGHYRVARILIDLCSDVNVCSLLAQTPLHVAAETGH
TSTARLLLHRGAGKEAVTSDGYTALHLAA---RNGHLATVKLLVEEKADVLARGPLNQTA
LHLAA---AHGHSEVVEELVSADV-IDLFDEQGLSALHLAA--QGRHAQTVETL------
-----------------------------LRHGA-HINLQSLKFQGGHGP----------
----------------------AATLLRRSKT----------------------------
------------------------
>gi|149633829|ref|XP_001511321.	Ornithorhynchus anatinus
-----------MDKES--------------SGSPG------------------------E
MGLLRAFDS---------------------AEF---------------------------
-----------------VSW------------E-KIG----------S-GGFGQVYKVR-
HVHWKTWLAIKCSPG---LHVDD-KDRVELLEEAKKMEMAKFRYILPVYGICRD-PVGLV
MEYMETGSLEKLLASEPLPWELRF---RIIHET---AVGMNFLHCMSPPLLHLDLKPANI
LLDAHYHVKISDFGLAKCSGLSHSHDLSMDGLCGTIA----YL----PPERIKEKNRFFD
TKHDVYSFA---------------IVIWGVLTQKKPFADEKNILHIMVKVVKGHRPELPP
VSKSRPRSCNNLIRL-MQKCWRDNPRERPTFQ----------------------------
--------------------EITSETEDLCEKPDDEIKET--QELDIKNPHEPKTEEMPA
LPAPKRASAPAFDADYSLSELLSQLDSET--SQTME--GPDELSRSSSESKLVST-----
----SSGKRLSGVSSVDSAFSSRGSLSLSFERENSVSDISTTDLHKRKLAEAITSGDTGK
LMK-------------ILQPQDVDLVLDGQSSLLHLAVEAGQEECVKWLLLNN-ANPNLT
NKRGSTPLHVAIEKKVRS-VVELILARKINV-----------------------------
---------NAKDEDQWTALHFAAQNGD---ECSTRLLLEKNASP---------------
------------------------SEVDFEGRTPMHVAC--QHGQENIVRILLRRGVDVS
PQGKDDWLPLHYAAWQGHLPIVKLLAK--------------------------------Q
PGVSVN---AQTLDGRTPLHMAAQRGHYRVARILIDLRSDVNVRNRLLQTPLHVAAETGH
TSTSRLLLNRGAEKEALTVEGCTALHLAS---RNGHLATAKLLLEEKADVLGAGPLSRTA
LHLAA---ANGHAGVVEELLGAVA-IDAADREGLTALHLAV--RGGHAETMEVL------
-----------------------------LKHGA-RINLQSLGAQAPPLLPGNSP-----
----------------------VATLLRRRNT----------------------------
------------------------
>gi|126337931|ref|XP_001368644.	Monodelphis domestica
----------MEKAKNVQLVVILAYYLLDTFGGPWVGVKFRSTTRRSAEDGRFNTPQAQV
VGLFPRFAPRPIAERALLEASGESSLFPGLGSLQRPKKFLVCGGAAMQRDQPLKVRSGNE
QWPESSMQPAGGGGVGAGAWNHSREALELLETQLRCSRCLNILREPVCLGGCEHIFCSVC
VGDCIGTECPVCHTPAWIQDVKINRQLDNMIQLCSRLRNLLHN--TTGTDEEESTPRT-R
ASLDEDENNKKFIKMWFSPRSKKV---RYVLNKTLVQTQPQPVENEQDYQ-AFEFSSSSL
EKDSPQRPKKVTRKTRKKQKKRSLVEINKKWDLEEEKQKEIHQ----PDESFNEKPKE--
-KSVSFCNQ---------------PSVLGTPENPPVLNG--DLLDHG------------S
VTEAVPTAVVTESSP-LPVTQADSVEMDRDSE----------------------------
--------------------VASSHPESFCEDNFTSETSLPLRNGGAWERQQPNSFVVPV
SKRPRRR-------RSQQRVRRASLSSDV----PLESLTPREESAPSPTSKS--------
----LADEPFLRVRNSDVLNDSINFSPHKSSGTSSSSLLNSPCQPWIVSSPSVVKMSPTS
PMT--------------------VKRNHRGETLLHIASIKGDIPSVERLLQNG-SDPNVK
DHAGWTPLHEACNHGHQK-VVELLLEHKALV-----------------------------
---------NTTGYQNDSPLHDAVRNGH---VSIAKLLLSHGASR---------------
------------------------SAVNIFGLRPVDYAE--TEAMKSV--LLLPEESEIY
EIGQCS--KSLNTSYRRDDPLVLLSSGLTSDQQKLLSKLSAVLKAKKCTEFNSMVTHIIV
PGDTAQ----RTMKCILGIIS----GCWILKFDWVKACLESRMCEPEEKYEILGGPQRSR
LNREQLL--------PKLFDGCYFYFEGIFK-HHSKDELVKLAKESGGQILNRKP-----
---------KPDSDVTQTINTVSYHARPDSDQRFCTQYIIY--DAFSNYHPER-------
-----------------------------VRQGK-VWMAPSNWFIDCLM-----------
----------------------AFQVLPVTK-----------------------------
------------------------
>gi|109299846|gb|ABG29498.1|	Danio rerio
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-------------------------------MGNQELEEVFVAVIRPKN------TTSLN
SKEYRAKSYEILLIEVPLEGKEKK---RKEVLL---GTKIHADSDRTKSILGF-VDETTK
PISNNQGIIGKRVVHMRKFLLDGDSGGKEASLFIVPI-----------NVKDNSKSVHHP
GSPSFYCLQ---------------DIMRVCSETSAHFSSSTSKMLLALD-------KWLA
EQHTVPHAIPALFRP--------APVDRVKTN----------------------------
--------------------VSNPAYAV-E-KQTDGTLHMGYTALEIKSKLMSLEKADLC
IQNPLYGSDLQYTNRVDKVIINPYFGLGA---------------PDYSKIQIPKR-----
----DKWQHSMTSVTEDKERQWVDDFPLHRSACEGDTELLSKLLDGGFSVKQLDSDHW--
-------------------------------APIHYACWHGKVEATKLLLEKGNCNPNLL
NGQLSSPLHFAAIGGHAE-IVQLLLQHPEIDR----------------------------
---------HIEDQQKRSPLQVCEENKQNNWEETVNLLQQASNKP---------------
-----------------------YEKVRIYRMDGSYRSVELKHGNNTTVQQIME-GMRLS
QETQQ-----YFTIWICSENLSLQLKPYHKPLQHLRMWSEIVTDLTALDPQRESPQLFLR
RDVRLPLEVEKKVEDPLSILILFDEARHCLLKGFLSTSDNKLITLASLLLQIIYGNYDSK
KHKRGFL----NEENLKSIVPISKVKSKAHHWTNRILHEYKSLSTSEGVSKEMHHLQRLF
LQNCWDIPTYGAAFFTGQVFTKAS----SSTHKVIRVYVGVNTKGLHLMNMETK------
------------------------VLHLSLEYGTFMWQLGQADQYVQIHSL---------
--ENKKNFVVHTKQAGL-----IVKLLMKLSGQIAPNDRAVSDKYAYG------------
------------------------
>gi|47219438|emb|CAG10802.1|	Tetraodon nigroviridis
------------------------------------------------------------
MGNEDSLED---------------------------------------------------
------------------------------------------------------------
-----VFVAVIRPKSQVSLSSKEYRAKAYEVNGGTRRQMIH----APLWCLS---PPALC
LLL-----IKILLIEVPLEGKEKK---RKKVLL---ATKIQSGGDKSKSILDY-VDTTVR
PISNNQGFIGKRVVYMRKFLLEGENEGKEASFFVVPV-----------GVKDNSKPVYSA
GSPSFYCFQ---------------DIMRVCSETSVHFCPITSKMLLALD-------KWLA
EQHTVPHAIPALFRP--------APVERVKTN----------------------------
--------------------VFNPAYSS-EGKLNDEGLLMGYNLLEIKTKMMSLEKADMC
ITNPLYGSDLQYTNRVDKVIINPYFGLGA---------------PDYTKIQIPKR-----
----DKWQHNPNCVNEDKDRQWVDDFPLHRSACEGDTELLSKLLDSAFSVTQMDSDQW--
-------------------------------APIHYACWHGKVEATKLLLEKGNCNPNLL
NGQLSSPLHFAAGGGHAE-IVQLLLQHPEIDRVGNMCLCSAYTPHTTEILYRLCEDFAVK
GVGITSPYQHIEDQQKRTPQQVCEENKQNDWEETVKLLQQAGSKPVRHTSGGYYYGRWPL
GRSKLLVLLCDLVCVCVCVLLLQYEKVRIYRMDGSYRSVELKHGNNTTVQQIME-GMRLS
QDTQQ-----YFTIWICSENLHLQLKPYHKPLQHLRIWTEIVTDLTVLDPQRETPQLFLR
RDVRLPLDVEKKVEDPLAILILFDEARHCLLKGFFPAPDSKLITLASLLLQIIYGNYESK
KHKQGFL----NEENLKSIVPISKVKSKAYHWTSRILHEYKALSTSEGVSKEMHHLQRLF
LQNCWDIPTYGAAFFTGQVFTKAS----ASNHKVLRVYVGVNTKGLHLMNMETKVKEKSR
LFSSERFRRKRCVWLDCCSVSYTQVLLISLEYGTFMWQLGHADQYVQIHSG---------
--NNKMNFIVHTKQAGL-----IVKLLMKLSGQMTPNDKG--------------------
------------------------
>gi|10719883|sp|P57078|RIPK4_HU	Homo sapiens
-----------MEGDG---------------GTPW------------------------A
LALLRTFDA---------------------GEF---------------------------
-----------------TGW------------E-KVG----------S-GGFGQVYKVR-
HVHWKTWLAIKCSPS---LHVDD-RERMELLEEAKKMEMAKFRYILPVYGICRE-PVGLV
MEYMETGSLEKLLASEPLPWDLRF---RIIHET---AVGMNFLHCMAPPLLHLDLKPANI
LLDAHYHVKISDFGLAKCNGLSHSHDLSMDGLFGTIA----YL----PPERIREKSRLFD
TKHDVYSFA---------------IVIWGVLTQKKPFADEKNILHIMVKVVKGHRPELPP
VCRARPRACSHLIRL-MQRCWQGDPRVRPTFQGNGLNGELIRQVLAALLPVTGRWRSPGE
GFRLESEVIIRVTCPLSSPQEITSETEDLCEKPDDEVKETA-HDLDVKSPPEPRSEVVP-
-ARLKRASAPTFDNDYSLSELLSQLDSGV--SQAVE--GPEELSRSSSESKLPSS-----
----GSGKRLSGVSSVDSAFSSRGSLSLSFEREPSTSDLGTTDVQKKKLVDAIVSGDTSK
LMK-------------ILQPQDVDLALDSGASLLHLAVEAGQEECAKWLLLNN-ANPNLS
NRRGSTPLHMAVERRVRG-VVELLLARKISV-----------------------------
---------NAKDEDQWTALHFAAQNGD---ESSTRLLLEKNASV---------------
------------------------NEVDFEGRTPMHVAC--QHGQENIVRILLRRGVDVS
LQGKDAWLPLHYAAWQGHLPIVKLLAK--------------------------------Q
PGVSVN---AQTLDGRTPLHLAAQRGHYRVARILIDLCSDVNVCSLLAQTPLHVAAETGH
TSTARLLLHRGAGKEAMTSDGYTALHLAA---RNGHLATVKLLVEEKADVLARGPLNQTA
LHLAA---AHGHSEVVEELVSADV-IDLFDEQGLSALHLAA--QGRHAQTVETL------
-----------------------------LRHGA-HINLQSLKFQGGHGP----------
----------------------AATLLRRSKT----------------------------
------------------------
