>gi|115918041|ref|XP_780071.2|	Strongylocentrotus purpuratus
------------------------------------MVHPTCVSNATLRSQRTG------
------------------------------------------------------------
----------------------------------DASNMKDVANSLSS----CPSI----
----------KLLSKRDQPLKPTGDAQLKYFPKVADFGDIIAFLSRQSYLPELSKTG---
SKDIENTPKKTGIKPIPLERQKKRKEEKDKVWEENVEKKVNSPCARV-TNMDNREAEKNL
GKESEEEVK-TVE--LKTIETNTTGVTPP---PFKFTDLLDITKSRRLQRYQN------R
TKPTESPDKNRGPVPDPRTPAP--R-------------KQYPKPIMIETSFLDNSPYIIP
VKKPEK----EKLPFDDNKDGPLIIPLDSEKAKLFESLNSYAPQVPFIPPPPLWSMVSTL
PRVPQPMMD--PPSYSPPSSPPPFYQPPSPEYTNPPPPIDY-DENVPRFRSNTLNYLHEV
KDYLTMTKKRNQVKQKLYHLQLEAPKPRLIPC------QSIGVYGPPHYGDEFHG--P--
VSREEADRLLTNGGDGSYLI-RESLRARGS-------FTLGLRLLGAT-------KHFRL
YFDGQHYVADKRFDTVHDLVADGLITMYVETKAADYIGRIEFEEPIYDKYSKQATFM---
---RPQESNSNGSTP-QSMPDHSPPGPPTKNSMVDGRNTRPFPG----PITVEKD-----
--HVFKVRIRYYDSGRSRVSSFEVHTFVGLNWCMFCGNFLWGLKSQGVKCTDCGLSTHKQ
CSKRVPRDC---TPDLRLIKRVYSVDLTTLARAHGVTTSLVIERCVEEIE--SRGLGLEG
LYRIPGMQDDVELIRQRFDKDGMI--ARIGSKDFPDTNAISG-AMKLYLRELPIPLVPFK
MYHAFVEATKK--------------------TNIHEKIEEFCV--ALDELYQT-------
FP-AHYHTLKLLMAHLVRVVQLQEENKMSIENLGIVFGPTLMRPPSN------QPVIDDL
YMIHFQKKSVEIMIEEFDTLFQ--------------------------------------
-------------------------------K----------------------------
------------------------------------------------------------
------------------------------------------------------------
----------------------------------------
>gi|73985844|ref|XP_541917.2|	Canis familiaris
------------------------------------MGAVAEMWQGLPL-----------
------------------------------------------------------------
----------------------------------APESRKRYSDIFRS----LDNL----
----------EI---------SLGNVTLEMPPGDP-------VLSGDPE-SDKTPTA---
TETNETSLWSGPSLEGPAP--LTGEELDLRLIRTKGGVDAALDYAKT-WSRYAKELLAWT
EKRASLELE-FAKSIMKIAEAGKVSIHQQSHMPLQYIYTLFLEHDLSLGALAM------E
TVAQ-QKRDYYQPLAAKRTEIEKWR-------------KEFKEQWLKEQKRMNEA-----
VQALRR----AQLQYVQRSE-------D------LWVRSQASPEDPAPQASP--GPSKQQ
ER--RRRSR--EEAQAKVQEAVALYQASVREAN------AR-QQDLEAAKQRIVSHVRK-
---LVLQGDEVLRRVTLGLFGLRGAQAERGPRAFAALAECCEPFEAGQRYQEFVR--A--
LQPEAPPPP-----PPAFSF-QEFVPTAHS-------SPLDIRKKPSG-------PPPPR
LDESAAEAGP-----WED---TGISW--QGTPG----PTPGSDVDSVGGGSESRSLD---
---SP--TSSPGSGT-RRLMKVSSIGT-ESSDDFEERDPDLVDG-------LENG-----
----PGTPFRKW-TLSSAAQTHRLRRLRGPAKCRECEAFMV----SGTECEECFLTCHKR
CLETLLILC--GHKRLPARTPLFGVDFLQLPRDFPEEVPFVITRCTAEIE--QRALGVQG
IYRVSGSRVRVERLCQAFENGRAL--VDMSGNSP---HDVSS-VLKRFLQELTDPVVPFH
LYDAFISLAKT------------LHADPGHDPGTPSPSPEVIR--SLKTLLVQ-------
LPDSNYNTLQHLVAHLFRVAAQFEENKMSANNLGIVFGPTLLRPPDGPGAAG-AGSVTCL
LDSGHQAQLVEFLIVYYEQIFGM---------DDLPVATEPPPQDPSPAPGPLTNNP-QP
PPS-NLAPDPLPLVLASDPDTDSELHGTLE-KHPEATPPEIPTPQSDHRE-VAEDTKKEE
EEVSSQGPEDSLLGTQSRGHFSRQPVKYPRGGARPITHQLSSFALVASKLCEETPITSVT
RGSLRRRGPGPVTSSPEGSPLRRTPLPKHFEITQETARLLSKLPSEAMPK-----ATCCP
DPQPEEAEDHL-----------------------------
>gi|118116753|ref|XP_423689.2|	Gallus gallus
---------------------------MNGLGSRDDARVADGFPAGFLPPEHNSHLGIPA
ASWAPSHCPTPEHRAGEVLRVTQHLKSIDGKFQCLRELFQKGEDFSGPVKAKLSDLLHSI
FSFLNTYPAVTGDAIHLAIATLIANINGLDHQERAPENKKRYSEIFRS----LDAI----
----------EI---------SIGNAAVDMFIGDA-------DGTGDAE-LSTEREI---
IVPSEDLSKSKSSLERQMQGDLTVEEADEMLIKCEGGIDAALEYAKM-WCKYVKELLSWI
EKRLNYETE-FAKGIMKIAESGRNAIIHQSNMPLRMLYVMVLENDIKIGNAAS------E
TVGLLQQKEFYQPLSAKKNEIEKWR-------------KEFKDQWTKEQKRMNES-----
LSLLRK----ARLQYIQRCE-------EMEKAKQLSAKAEDEYQNSAIISPS--SAIKHL
EK--RRRSC--EEAQAKVQEAEALYRMCIGDAN------FR-RQELEKVRARIVSHIRK-
---LIYQGDEVLTWVTLRMFKQRQTQSEQIPVGYQHLSEVCKPYRVGEKYLEFIQ--A--
LQKKDIPME-------HFEF-EPLSSGGQR-------SPPSNKKK-----------TPLH
YTGCSKDGST-----PED---TPRRQFSPNGVN----KSLCSDTESLSGSCESRSLD---
---SP--SSSPGNST-RKLLKASSTGTMSSSDDFEERDSLQTSE-------NENG-----
---TSQQQFRNA-LLSSAAQTHRLRKLRGPTKCRECDTFMV----NGFECEECYLTCHKK
CLENLLITC--GHKKLPNRVPLFGIDFTQVPRDFPEEVPFIVVKCTSEIE--ARALGVQG
IYRISGSKARVEKLCQAFENGRSL--VELSEHSP---HDITG-VLKHFLKELSGPILLYQ
LYDNLIALAKE------------LQKAGEEKVDCTSFPSDPIQ--SMKDLLSK-------
LPGSNYNTLRHLIAHLYRVAEKYEENKMSPNNLGIVFGPTLIRPGSGS-----DVSMSCL
VDSGYQAQIVEFLIQNYERVFGM---------EDLPS-----------------------
----SLSLGCENPLQEASTEKDEEHQ-----SPNTAQNVTLEV-----------------
------------------------------------------------------------
------------------------------ELADTELGLLTLL-----------------
----------------------------------------
>gi|148227826|ref|NP_001085770.	Xenopus laevis
---------------------------------------MASGGGGVSGTSTPSG-----
------------------------------------------------------------
----------------------------------SSEGRKRFSEIFRD----FDAL----
----------EI---------SLGNETVEMFLNDSE------HLELHPD-EEEESLI---
STPLELSRASVD---------QGVEETDDILLHSEGGVESALNYAKR-WCKYVREVLGYM
EKRLNYELE-FAKNITKLAESTRFIFTQQASMPLQCVYLLLMDHETQTANAAH------D
TVAQLQLKKYCQPLSAKKTEIEKWR-------------KEFREQWQREQKRMIDS-----
CAALRK----SRQLYIQRCD-------DLEKAKQLSAKIEEEQGHTG-------SANKLV
EK--RRKSR--EEAQSKATEAEMAYRYCVQEAN------AR-SQQQEKVRERIVSHIRK-
---LIIQGDQVLKEVTMNLLRMKQSQCEVIPCGYGDLLTTCDPYESGTRYLQFIL--T--
LPRKHTDPE-------RFTF-EEYIPTGQR-------SPSVGRRKNA--------VQLVR
VSSSLSDLNV-----KNE---DGTVKMYAGERGSWGSKFPSSDSESMGATSESRSQE---
---ST--SDSPGDFA-RRVPKASSTGT-MSSDDLDERDSFNTEDVDSTDANSENG-----
---LPLQSMERLGVLSLAAQSHRLKRTRVPSKCRECENFMV----SGVECEECLLTCHRK
CLENLLIKC--GHRKLPPKVPLFGVDFSQFPRYFPEEVPFIIVRCTAEIE--QRALGQQG
LYRISGAKARVEKLLQAFENGREL--VDLSGHSP---HDITS-SLKHFLKQLPDSVVPYQ
LYEQFMAFSRD----------------YLEDTKENETGHSAIH--QMKELLCR-------
MPHSHYNTLRHLTAHLYRVSERFEDNKMNPNNLGIIFGPTLIRPLPGQ-----DISVNCL
IDTGYQSQAVEFLINNYEKIFGM---------DDLPSARPQNSEE---------------
--------------EPADVEGAEDSRRPFDVKGVTETSSDKGLSDADRLQ----------
--EEVEEDQEVENATYSRNHFSRLPIR---------------------------------
---------------------------------------LVRMEQSKTEG-----AETDG
EAEGEEG---------------------------------
>gi|148676178|gb|EDL08125.1|	Mus musculus
MAQWLRALAACSSRGPEVGGSIRPWKQMYVVLRGHSLYLYKDRREQTTPSEEEQPISVNA
CLIDISYS----------------------------------------------------
----------------------------------ETKRRNVFRLTTSD----CECLFQAE
DRDDMLSWIKTIQESSNLNEEDTGVTNRDLISRRIKEYN---SLLSKTEQLPKTPRQ---
SLSIRQTLLGAKSEPKTQSPHSPKEESERKLLSKD---DTSPPKDKGTWRRGIPSIV---
--RKTFEKKPAATGTFGVRLDDCPPAHTNRYIPLIVDICCKLVEERGLEYTGIYRVPGNN
AAISSMQEELNKGMADIDIQDDKWRDLNVISSLLKSFFRKLPEPLFTNDKYADFIEANRK
EDPLDRLRTLKRLIHDLPEH-------HFETLKFLSAHLKTVAENSEKNKMEPRNLAIVF
GPTLVRTSE--DNMTHMVTHMPDQYKIVETLIQ------HHDWFFTEEGAEEPLTAVQE-
-----ENTVDSQPVPNIDHLLTNIGRTGVLPGDVSDSATSDSAKSKGSWGSGKDQ--Y--
SRELLVSSI-----FAAASR-KRKKPKEKA-------QPSSSEDELDS-------VFFKK
ENTEQSHSEI-----KEE---SKRESETSGSKQRVVVAKESNTKKDSGTTKEEKKIP---
---WE--EPSPPHSS-K---RNRSPTLSCRLAMLKEGPRSLLTQ---KPHCEETG-----
---SDSGTLLS--TSSQASLLRSSTKKSTSPETKHSEFLSI----AGTTTSDYSTTSSTT
YLTSLDSSR--LSPEVQSVAESKGDEADDERSELVSEGRPVETDSESEFPVFPTTLTSDR
LFR--GKFQEVARVSRRNSEGSEA-------------SCTEG-SLTPSLDSRRQQFSSHR
LIECDTLSRKKSAR---------FKSDSGSPGDTRTEKETPALA-KMFDVMKKGKSTGSL
LTPSRSESEKQEATWKTKIADRLKLRPRAPAD--DMFGVGNQKPTAETAK---RKNIKRR
HTLGGHRDATEISVLSFWKAHE-------------------QSADKESELSAVNRLKPKC
SAQ-DLSISDWLARERVRTSASDLSRGEGL-EPQAESPSVLGTPISTHSP----------
---PSQQPEARVAATSTLASTSQSPLFTPPQSPDQINRES--------------------
-----------------------------FQNMSQNASSTANIHPHKQSESPDTKAETPP
----------------------------------------
>gi|149757303|ref|XP_001503565.	Equus caballus
---------------------------------------MDAAEPGLTP-----------
------------------------------------------------------------
----------------------------------APESRKRYSDIFRS----LDNL----
----------EI---------SLGNVTFEMLVGDP-------VLSGDPE-PDKTPTA---
TVTSETSHWSGPSSEGPAP--LTGEELDLRLIRTKGGVDAALEYAKT-WSRYAKELLAWT
EKRASYELE-FAKSIMKIAEAGKVSIHQQSHMPLQYVYTLFLEHDLNLGTIAM------E
TVAQ-QKRDYYQPLAAKRTEIEKWR-------------KEFKEQWLKEQKRMNEA-----
VQALRR----AQLQYVQRSE-------D------LRVRSQASPEDMTPQASL--GPSKQQ
ER--RRRSR--EEAQAKAQEAEALYQACVREAN------AR-QQDLEAAKRRIVSHVRK-
---LVLQGDEVLRRVTLGLFGLRGAQAERGPRTFATLAECCKPFEPGQRYQEFVR--T--
LQPEAPPPP-----PPAFSF-QEFVPTVHSPQTSPFTSPLDTRKKLSG-------PLPPQ
LDETVAEPGP-----WED---AGTGW--QGTPG----PTPGSDVDSVGGGSESRSLD---
---SP--TSSPGSGT-RRLMKVSSTGT-ESSDDFEERDPDLGDG-------LENG-----
----TGSPFRKW-TLSSAAQTHRLRRLRGPAKCRECEAFMV----SGTECEECFLTCHKR
CLETLLILC--GHRRLPARTPLFGVDFLQLPRDFPEEVPFVITRCTAEIE--QRALGVQG
IYRVSGSRVRVERLCQALENGRAL--VDLSGNSP---HDVSS-VLKRFLQELTDPVVPFH
LYDAFISLAKT------------LHAEPGLDPRTPSPSPEVIR--SLKTLLVQ-------
LPDSNYNTLRHLVAHLFRVAAQFEENKMSANNLGIVFGPTLLRPPDGPGAVG-AGPVTCL
LDSGHQAQLVELLIVYYEQIFGM---------DELPLATQPAPQDPSPAPGPLTTSP-QP
PPP-HLALEPLPPALTSDPDPDPEPHGTLE-KHPEAMPPKIPTPQSDQREEVAEDTKDEG
REAPSQGPEDSSLGTQSRGHFSRQPVKYPRGGVRPVTHQLSSLALVASKLCEETPDTSVP
QGSLRRRGPGPAAASPEGSPLRRTPLPKHFEITQETARLLSKMHNEAVPK-----ATCSR
DPQPEEVEDHL-----------------------------
>gi|149640476|ref|XP_001510811.	Ornithorhynchus anatinus
---------------------------MHSLLYTSSEFATVSGRLRFPQVTTAAGVRG--
------------------------------------------------------------
----------------------------------CGESGNHSPVLFPP----SSGL----
----------EFPVFFLSPSSPRHPESFPKFEMGPRSHRA--SLQGCTILKRFRCLF---
STFVFLSPIYPQTPRGKEPYSLIKTVAYVPIHQVGEEVENLRRLSAA-QRKFAHSL----
---RDFKFE-FIGDAETDDERCIDASLRE-----FSNFLKNLEEQREIMALSV-----TE
TLIKPLEKFRKEQLGAVKEEKKKFD-------------KETEKNYSLVDKHLNLS-----
----AK----KKDSHLQEAD----------------VQVEQNRQHFYELSLE--YVCKLQ
EIQERKKFEFVEPMLSFFQGMFTFYHQGHELAK------DF-NHYKMELQINIQNTRNR-
-----FEGTRSEVEDLMNKIRKNPKEQKRASQFAAEGYLYVQEKRPAPFGSSWVKHYC--
MYRKTAK---------KFTM-IPFEHRSG--------GKLGDGEIFS-------------
LIECTKRPMD-----STD-------------------RRFCFDVET--------------
-------SDRPGIPI--------------TMQAFSEEERKQWME-------ALGG-----
----------------KEALFHNLNRAS-P------------------------------
--------------RPEERAQLDKMGFT------------ILRKCISAVE--TRGINDQG
LYRVVGVSSKVQRLLSVLMDAKTCSEVDLENSSDWEVKTITS-ALKQYLRSLPEPLMTYE
LHGQFIVPAKC---------------------GTPESRVNAIH-----FLVHK-------
LPEKNREMLDILVKHLTNVSNHSKQNLMTVANLGVVFGPTLMRPQ--------EETVAAI
MDLKFQNIVVEILIENHEKIFRTLPDATLSEPTSMSISPPNAPPRQSKRQGQRNKRPVAV
YNL-CLELEDVDNYTSPKEDTPTGSQESLS-SQSPTPAMSSSPTGPDKNHLIPDAVDCVD
WTSNHPNQPRAPMVQWLNPQPPSSPVSTSAAAPPSPVSPSFPTPFLTLPLLAASDKSVES
TVNRKARAVYPCVAEHSS------------ELSFDVGAIFEDVQTSREPGWLEGTLNGKR
GLIPQNYVKLL-----------------------------
>gi|47223057|emb|CAG07144.1|	Tetraodon nigroviridis
-------------------------------------INFKEVNP---------------
------------------------------------------------------------
-----------------------------------DSAKAIFGDIHTS----IDTL----
----------AF---------TFGNVVSDFLMGDVDSG----SGLGTPQ-ARRSRSFDNL
SVDPEGYVSEKTVFDGPRVPLSREEEVDLALLKHDSGVESALLYAKA-WSRYIKDLLAWM
EKRLAMDIE-YAKYYAKMAESAKTLASQRDYMPFSHIYVSTFKQEAEYRQLLI------Q
TALALQTNKFMQPLVARKNELDKLR-------------KDVKEQWQKEQKKMQEA-----
EAALRK----AGALKTQRRE-------EYEKAQSSTNRSLEEQSN---------AVNKQL
EK--KRKLE--EEALQKAEEAQEQYQSCVADAG------IR-KMDLANAKSTILTQIRK-
---MVFQCDLTLKAATVNWFQMQQAQVVSLPAHYQALSDNAKLYEPGECYADFVRNLPKN
LQKEQLHSDSIPTDSSRFMFNKRSVGSSHSSHGNLSQASITSCDVLSGDGVDIPQQHPPT
MSEQRSHSSADIQALRGQ---PTVRPWASGSPGSH--GGMCSDSESAGGSSESRSMD---
---SP--TASPGDFK-RRLPRTPSTGTMSSADDLDEREPPSPSDNGLADMVTGTA-----
---SSPGPFRNV-QMSKAALTHKLRKLRAPSKCRECDSLVV---FHGAECGECSLACHKK
CLETLAIQC--GHKKLQGRLQLFGIDFAQASRNSPDGIPFIIKKCTSEIE--SRALNIKG
IYRVNGAKSRVEKLCQAFENGKDL--VELSDLSP---HDISN-VLKLYLRQLPEPLVLYR
YYNDLIGLAKECQRAIVEEADKLQKNQTGDKPGSSVQLNRVVI--KMRDFLLQ-------
LPTANYRTLHFVIAHLHRVSEQAEENKMTASNLGIIFGPTLIKPRQADA----EVSLSSL
VDYPYQALIVEMLVRHFHTVFDV---------SLLPA-----------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
----------------------------------------
>gi|109075868|ref|XP_001096942.	Macaca mulatta
------------------------------------------------------------
------------------------------------------------------------
----------------------------------MTSDHRIQSPCVHS----LWSS----
---------------------NRASSLEVMMPGGK------------------TAAV---
WLELMSVTRSMR---------VRGSVIQKV---NEEGLSVA-------QRKFAHSL----
---RDFKFE-FIGDAVTDDERCIDASLRE-----FSNFLKNLEEQREIMALSV-----TE
TLIKPLEKFRKEQLGAVKEEKKKFD-------------KETEKNYSLIDKHLNLS-----
----AK----KKDSHLQEAD----------------IQVEQNRQHFYELSLE--YVCKLQ
EIQERKKFEFVEPMLSFFQGMFTFYHQGHELAK------DF-NHYKMELQINIQNTRNR-
-----FEGTRSEVEELMNKIRQNPKDHKRASQFTAEGYLYVQEKRPAPFGSSWVKHYC--
MYRKAAK---------KFNM-IPFEHRSG--------GKLGDGDVFF-------------
LKECTKRHTD-----SID-------------------RRFCFDIEA--------------
-------ADRPGVSL--------------TMQAFSEEERKQWLE-------ALGG-----
----------------KEALSHSFNTAIIP------------------------------
--------------RPEGSAQLDKLGFT------------IIRKCISAVE--TRGINDQG
LYRVVGVSSKVQRLLSMLMDVKTCHEVDLENSADWEVKTITS-ALKQYLRSLPEPLMTYE
LHGDFIVPAKS---------------------GSPESRVNAIH-----FLVHK-------
LPEKNKEMLDILVKHLTNVSNHSKQNLMTVANLGVVFGPTLMRPQ--------EETVAAL
MDLKFQNIVVEILIENHEKIFRMPPDTTFPEPTCLSASPPNAPPRQSKRQGQRTKRPVAV
YNL-CLELEDGDNPNPSKEDTPTGSLDSLS-SPSPVTAALPGPPGPDKNHLLADGGSFGD
WASTIPGQTRSSMVQWLNPQSPTTTSSNP--AVTPPSPGSSPFLFSPPATVVDKPPESVS
--SRKARAVYPCEAEHSS------------ELSFEIGAIFEDVQTSREPGWLEGTLNGKR
GLIPQNYVKLL-----------------------------
>gi|2896796|gb|AAC03237.1|	Homo sapiens
-------------------DLLEARRPRAHECLGEALRVMHQIISKYPLLNTVETLTAAG
TL----------------------------------------------------------
----------------------------------IAKVKAFHYESNND----LEKQ----
----------EFEKALETIAVAFSSTVSEFLMGEVDSS----TLLAVPPGDSSQSME---
SLYGPGSEGTPPSLEDCDAGCLPAEEVDVLLQRCEGGVDAALLYAKN-MAKYMKDLISYL
EKRTTLEME-FAKGLQKIAHNCRQSVMQEPHMPLLSIYSLALEQDLEFGHSMV------Q
AVGTLQTQTFMQPLTLRRLEHEKRR-------------KEIKEAWHRAQRKLQEA-----
ESNLRK----AKQGYVQRCE-------DHDKARFLVAKAEEEQAGSAPGAGS--TATKTL
DK--RRRLE--EEAKNKAEEAMATYRTCVADAK------TQ-KQELEDTKVTALRQIQE-
---VIRQSDQTIKSATISYYQMMHMQTAPLPVHFQMLCESSKLYDPGQQYASHVR--Q--
LQRDQEPDV-------HYDF-EPHVSANAW-------SPVMRARKSS-------------
--FNVSDVAR-----PEA---AGSPPEEGGCTE----GTPAKDHRAGRGHQVHKSWPLSI
SDSDSGLDPGPGAGDFKKFERTSSSGTMSSTEELV--DPDGGAGASAFEQADLNGMTPEL
PVAVPSGPFRHE-GLSKAARTHRLRKLRTPAKCRECNSYVY---FQGAECEECCLACHKK
CLETLAIQC--GHKKLQGRLQLFGQDFSHAARSAPDGVPFIVKKCVCEIE--RRALRTKG
IYRVNGVKTRVEKLCQAFENGKEL--VELSQASP---HDISN-VLKLYLRQLPEPLISFR
LYHELVGLAKDSLKAEAEA----KAASRGRQDGSESEAVAVALAGRLRELLRD-------
LPPENRASLQYLLRHLRRIVEVEQDNKMTPGNLGIVFGPTLLRPRPTEA----TVSLSSL
VDYPHQARVIETLIVHYGLVFE--------------EEPEETPGGQDESSNQRAEVVVQV
PYL-EAGEAVVYPLQEAAADGCRESRVVSN-DSDSDLEEASELLSSSEASALGHLSFLEQ
QQSEASLEVASGSHSGSEEQLEATAREDGDGDEDGPAQQLSGF-----------------
------------------------------NTNQSNNVLQAPLPPMRLRG-GRMTLGSCR
ERQPEFV---------------------------------
>gi|114676286|ref|XP_512530.2|	Pan troglodytes
----------------------------------MDSLITTQELQRLPP-----------
------------------------------------------------------------
----------------------------------GPEGRKRYSDIFRS----LDNL----
----------EI---------SLGNVTLEMLAGDP-------LLSEDPE-PDKTPTA---
TVTNEASCWSGPSPEGPVP--LTGEELDLRLIRTKGGVDAALEYAKT-WSRYAKELLAWT
EKRASYELE-FAKSTMKIAEAGKVSIQQQSHMPLQYVYTLFLEHDLSLGTLAM------E
TVAQ-QKRDYYQPLAAKRTEIEKWR-------------KEFKEQWMKEQKRMNEA-----
VQALRR----AQLQYVQRSE-------D------LRARSQGSPEDSAPQASP--GPSKQQ
ER--RRRSR--EEAQAKAQEAEALYQACVREAN------AR-QQDLEIAKQRIVSHVRK-
---LVFQGDEVLRRVTLSLFGLRGAQAERGPRAFAALAECCAPFEPGQRYQEFVR--A--
LRPEAPPPP-----PPAFSF-QEFLPSSNS-------SPLDIRKKLSG-------PLPPR
LDENSAEPGP-----WED---PGTGWRWQGTPG----PTPGSDVDSVGGGSESRSLD---
---SP--TSSPGAGT-RQLVKASSTGT-ESSDDFEERDPDLGDG-------LENG-----
----LGSPFGKW-TLSSAAQTHQLRRLRGPAKCRECEAFMV----SGTECEECFLTCHKR
CLETLLILC--GHRRLPARTPLFGVDFLQLPRDFPEEVPFVVTKCTAEIE--HRALDVQG
IYRVSGSRVRVERLCQAFENGRAL--VELSGNSP---HDVSS-VLKRFLQELTDPVIPFH
LYDAFISLAKT------------LHADPGDDPGTPSPSPEVIR--SLKTLLVQ-------
LPDSNYNTLRHLVAHLFRVAARFMENKMSANNLGIVFGPTLLRPLDGPRAAS-AIPVTCL
LDSGHQAQLVEFLIVHYEQIFGM---------DELPQATEPPPQDSSPAPGPLTTSS-QP
PPP-HLDPDSQPPVLASDPGPDPQHHSTLE-QHPTATPTEIPTPQSDQREDVAEDTKDGG
GEVSSQGPEDSLLGTQSRGHFSRQPVKYPRGGVRPVTHQLSSLALVASKLCEETPITSVP
RGSLRGRGPSPAAASPEGSPLRRTPLPKHFEITQETARLLSKLDSEAVPR-----ATCCP
DVQPEEAEDHL-----------------------------
>gi|52345804|ref|NP_001004948.1	Xenopus tropicalis
--------------------------------------MPRNQSPVISDTSTPSG-----
------------------------------------------------------------
----------------------------------SSEGRKRFSEIFRD----LDAL----
----------EI---------SLGNETVEMFLNDSE------QLESHPD-EEEESLI---
STPLELSRTSAD----------HVEEADDVLLHSEGGVESALNYAKR-WCKYIREVLGYM
EKRLNYEIE-LAKNTVKLSESTRLIFTQQASMPLQGVYLLLMDHETHTANAAI------D
MVGQLQMKKYYQPLSAKKTEIEKWR-------------KEFREQWQREQKRMMDS-----
CAALRK----SRQLYIQRCD-------DLEKAKLLSAKIEEEQIASGHTG----SANKLV
EK--RRKSR--EEAQSKAIEAEASYRSCVQEAN------AR-SQQQEKVRERIVSHIRK-
---LIIQGDQVLKEVTMNLLRMKQSQFEAIPCGYGDLLTTCDPYESGTRYLQFIL--T--
LPRKHTDPE-------KFTF-EEYIPACQR-------SPSVGRRKNA--------VQLVR
VSSSLSELYA-----KTE---DGILKISAGERGSWGSKIPSSDSESMGGTSESRSQE---
---SP--SDSPGDFV-RRVPKASSTGT-MSSDDLDERDSFNAEDVDSTDATSENG-----
---LPLHSMDRLGVLSLAAQSHRFKRTRVPTKCRECENFMV----SGVECEECFLTCHRK
CLENLLIRC--GHRKLPSKVPLFGVDFSQFPRYFPEEVPFIIVRCTAEIE--QRALGQQG
LYRISGAKARVEKLLQAFENGRDL--VDLSGHSP---HDITS-ALKHFLKQLPDSVVPYH
LYEQFMAFSRE----------------FLEDTKENETGNDAIH--QMKDLLCS-------
MPHSNYNTLRHLTAHLYRVSERFEDNKMNPNNLGIIFGPTLIRPLPGQ-----DISVNCL
IDTGYQSQAVEFLINNYEKIFGM---------DDLPSTRPQNSEEEAADVG---------
----GAEAAEVGGAEAAEVGGAEDSRGSFVIKEVTETSSDGGLPGISDGDRLPHDVKEDQ
EAENA---------TYSRNHFSRLPIK---------------------------------
---------------------------------------LVRMEQTKTEG-----AETDG
EAEDEEG---------------------------------
>gi|149021184|gb|EDL78791.1|	Rattus norvegicus
---------------------------MYVVLRGHSLYLYKDRREQTTPSEEEQPISVNA
CLIDISYS----------------------------------------------------
----------------------------------ETKRRNVFRLTTSD----CECLFQAE
DRDDMLAWIKTIQESSNLNEEDTGVTNRDLISRRIKEYN---SLLSKTEQLPKTPRQ---
SLSIRQTLLGAKSEPKTQSPHSPKEESERKLLSKD---DTSPPKDKGTWRRGIPSIV---
--RKTFEKKPAATGTFGVRLDDCPPAHTNRYIPLIVDICCKLVEERGLEYTGIYRVPGNN
AAISSMQEELNKGMADIDIQDDKWRDLNVISSLLKSFFRKLPEPLFTNDKYADFIEANRK
EDPLDRLRTLKRLIHDLPEH-------HFETLKFLSAHLKTVAENSEKNKMEPRNLAIVF
GPTLVRTSE--DNMTHMVTHMPDQYKIVETLIQ------HHDWFFTEEGAEEPLTAVQE-
-----ENTVDSQPVPNIDHLLTNIGRTGVLPGDVSDSATSDSTKSKGSWGSGKDQ--Y--
SRELLVSSI-----FAAASR-KRKKPKEKA-------QPSSSEDELDS-------VFFKK
ENMEPSHSEI-----KEE---SKRESETPGRKQRVVVAKDSNTKKDTGTTKEEKKMP---
---SD--EPSPPHSS-K---RNRSPTLSCRLAMLKESPRSLLTQ---KPHCEETG-----
---SDSGTL-----SSQASLARSSTKKSTSPETRHTEFLSN----AGTITSDYSTTSSTT
YLTSLDSSR--LSPEVQSVAESKGDEADDERSELVSEGRPVETDSESEFPVFPSALTSGQ
-FR--GKLQEVARSSRRNSEGSEA-------------SCTEG-SLTPSLDSRRQQFSSHR
LIECDTLSRKKSAR---------FKSDSGSPGDTRTEKETPALA-KMFDVMKKGKSTGSL
LTPSRSESEKQEATWKTKIADRLKLRPRAPAD--DMFGVGNQKPTAETAK---RKNIKRR
HTLGGHRDATEISVLSFWKAQE-------------------QSADKESELSAVNRLKPKC
SAQ-DLSISDWLARERIRSSASDLSRSEGC-EPQAESPSVLGTPTSTHTP----------
--PPSQQPEARAAASTS-ASTSQPPLSTPPQSPDQINGDS--------------------
-----------------------------FQNTSQNASSAANAHPHKLSESPNTKTESPP
CL--------------------------------------
>gi|50843948|ref|NP_078881.3|	Homo sapiens
------------------------------------------------------------
------------------------------------------------------------
----------------------------------------------MG----LQPL----
----------EF------------------------------------------------
SDCYLDSPWFRERIRAHEAELERTNKFIKELIKDGKNLIAATKSLSVAQRKFAHSL----
---RDFKFE-FIGDAVTDDERCIDASLRE-----FSNFLKNLEEQREIMALSV-----TE
TLIKPLEKFRKEQLGAVKEEKKKFD-------------KETEKNYSLIDKHLNLS-----
----AK----KKDSHLQEAD----------------IQVEQNRQHFYELSLE--YVCKLQ
EIQERKKFEFVEPMLSFFQGMFTFYHQGHELAK------DF-NHYKMELQINIQNTRNR-
-----FEGTRSEVEELMNKIRQNPKDHKRASQFTAEGYLYVQEKRPAPFGSSWVKHYC--
MYRKAAK---------KFNM-IPFEHRSG--------GKLGDGEVFF-------------
LKECTKRHTD-----SID-------------------RRFCFDIEA--------------
-------ADRPGVSL--------------TMQAFSEEERKQWLE-------ALGG-----
----------------KEALSHSFNTAIIP------------------------------
--------------RPEGNAQLDKMGFT------------IIRKCISAVE--TRGINDQG
LYRVVGVSSKVQRLLSMLMDVKTCNEVDLENSADWEVKTITS-ALKQYLRSLPEPLMTYE
LHGDFIVPAKS---------------------GSPESRVNAIH-----FLVHK-------
LPEKNKEMLDILVKHLTNVSNHSKQNLMTVANLGVVFGPTLMRPQ--------EETVAAL
MDLKFQNIVVEILIENHEKIFRTPPDTTFPEPTCLSASPPNAPPRQSKRQGQRTKRPVAV
YNL-CLELEDGDNPYPSKEDTPTSSLDSLS-SPSPVTTAVPGPPGPDKNHLLADGGSFGD
WASTIPGQTRSSMVQWLNPQSPTTTSSNS--AVTPLSPGSSPFPFSPPATVADKPPESIR
--SRKARAVYPCEAEHSS------------ELSFEIGAIFEDVQTSREPGWLEGTLNGKR
GLIPQNYVKLL-----------------------------
