>gi|91088391|ref|XP_972597.1|	Tribolium castaneum
------------------------------------------------------------
--------------------------MNTSLSRGCSYSPRESF-----------------
------------------------------------------------------------
-----------------------------EYTAL-QFAARRGSLEQVRYLIESGTDLD--
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-----------------------------TGPDPALHLALRKQNTAIAHVLLHAGADFEI
KDSHGDYPIHIACTLGLLDVVHALCALGCSVE---VLTAKGLSPLHLAAKNGHIHVVRCL
CAAGCNIDIRNSDN----------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
----------------------IRADITALK---------------------------YG
HNDIAELLDR----LRVTGQRDTLARQLVPTSKPALRLNLRLLGHC------GVGKTSLV
KSLSAG--------LFARPSSPIN---------------------------TQIEMDVTS
RQNSLSFE-------------------SSGNYQSTNGISVQNMDISNVGETTVWEFSGQE
NYFPIYHHFLWPSPHSLTLVLFSLEDSPSIQVQQVCFWLNFLLARQPADLPSCKKKKLQN
YLKFMLVATHVDLTRAVKTQNGEWICPDAQKTLETVRKIIPHVPNLMSSVVIMDTNVPAS
YPFKQLKSTLAELKQECLQDYLTSRKGYNLITSRVLKQTVGTWTGLLEATLAWLNSLQKD
YEQFPVLSRSTFSELLRSQVNILASDHHIQELLQQLHFMGEVF-----CVQDLVVVSVSW
L------------------GGQLLGELFSSDFFLH----ARVTGVYTSEDFQASFNQCDA
LGALDLLEALDVCVQCDIEGEIEY-------EFPIYNHVETLEGLWDSEDPRYASKGSQY
GGLRLYTPPGTYHQFKSIFPHIQVE--LRRAILANYSNNDS----DMDLYQWHLGSKLCN
TELESLITLEEDEVALQFIEIKIRGPNNSSQYCFYFLEQIMQTINHALLRVCPGLLIEKH
VLSPLELKRHSEGPFCYPSDIITTAML--EAESTLDVALYNPNVDAQE---TIAQLIMF-
------------------SDLDLAGNIQWGCALRIQDLAPPIKLKLC--GLLDPP-----
----------------ERHGRDWCLLAL-RLGLCQDKI--------------AALDSQHS
SHTMRLLTTADCSIGALITSLHELDRLDAAEVVLRSAPIFKIIEHVSV------------
------------------------------
>gi|157106389|ref|XP_001649301.	Aedes aegypti
---------------------------------------------------TPLHTAAGK
GNIEMVKLLIDHNANIDTKDDEGCTPLHYASRNGNLEMVKLLIDNRAN------------
------------------------------------------------------------
--------------------VDTTQN--EGWTPL-HYASQNGHIDVVKLLIDNRANVDT-
--------T---------------------------------------------------
------------------------------------------------------------
-------------------------------------------------QNEGCTPLHKA
AENGHLDVVKLLIDNKANVDTAQ------SEGWTPLHYASRNGNLELVKLLIDNRANVDT
AQYEGWTPLHYASRNGQLDVVKLLIDNRANVD---TTQNEGCTPLHYASQNGNLELVKLL
IDNRANVDTAQYEGWTPLHYASQN------------------------------------
------------------------------------------------------------
-GQLDVVKLLIDNRANVDTTQNEGCTPLHYASRNGNLELVKLLIDNRANVDTAQY----E
GWTPLHYASRNGQLDVVKLLIDNRANVDTTQNEGCTPLHYASR---------------NG
NLELVKLLIDNRANVDTAQYEGWTPLHYASQNGQLDVVKLLIDNRANVDTTQNEGCTPLH
YASRNGNLELVK--LLIDNRANVDTAQYEGWTPLHYAS-------------RNANVDTTQ
NEGCTPLHYASRNGNLELVKLLIENRANVDTAQNEGWTPLHYSSQNGHLKVVKLLIEN--
--------KANVDTTQNEGWTPLHYAFQNGHLEVVKFLID-----NGANVDTMNTRGSTS
FHIVSQNGRLVLVKLLIDNRANVDTTDNEGWTPLHYASQNGH-LEVVKFLIDNGANFDTK
NTRGSTSFHIASKNGRLEVVKLLIDNGANV---------------DTTNNEGWT------
------------------PLHYASRNGHLEVVKLLIDNGANVDTKNA-RGSTSFHIVSQN
G------------------RLEVVKLLIDNRANVD---TTDNEGWTPLHYASRNGHLEVV
KLLIDNGANVD---TKNTRGSTSFHIASKNGRLEVVKLL--IDNGA--NVDT--TNNEGW
TPLHYASRNGHLEVVKLLI-----------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------DNGANVDTKNARGSTSFHIVSQN--GRLEVV-----
----------------KLLIDNGANVDT--------------------------------
TYNERWTLLHDASLNGHLEVVKLSID----------------------------------
------------------------------
>gi|21356447|ref|NP_648148.1|	Drosophila melanogaster
---------------------------------------MVTENGAQGDGNTSFLRAARA
GNLERVLEHLKNNIDINTSNANGLNALHLASKDGHIHVVSELLRRGAI------------
------------------------------------------------------------
--------------------VDSATK--KGNTAL-HIASLAGQEEVVKLLLEHNASVNV-
--------Q---------------------------------------------------
------------------------------------------------------------
-------------------------------------------------SQNGFTPLYMA
AQENHDAVVRLLLSNGANQSLAT------EDGFTPLAVAMQQGHDKVVAVLLES----DT
RGKVRLPALHIAAKKDDVKAATLLLDNDHNPD---VTSKSGFTPLHIASHYGNQNIANLL
IQKGADVNYSAKHNISPLHVAAKW------------------------------------
------------------------------------------------------------
-GKTNMVSLLLEKGGNIEAKTRDGLTPLHCAARSGHEQVVDMLLERGAPISAKTK----N
GLAPLHMAAQGEHVDAARILLYHRAPVDEVTVDYLTALHVAAH---------------CG
HVRVAKLLLDRNADANARALNGFTPLHIACKKNRLKVVELLLRHGASISATTESGLTPLH
VAAFMGCMNIVI--YLLQHDASPDVPTVRGETPLHLAARANQTDIIRILLRNGAQVDARA
REQQTPLHIASRLGNVDIVMLLLQHGAQVDATTKDMYTALHIAAKEGQDEVAAVLIEN--
--------GAALDAATKKGFTPLHLTAKYGHIKVAQLLLQ-----KEADVDAQGKNGVTP
LHVACHYNNQQVALLLLEKGASPHATAKNGHTPLHIAARKNQ-MDIATTLLEYGALANAE
SKAGFTPLHLSSQEGHAEISNLLIEHKAAV---------------NHPAKNGLT------
------------------PMHLCAQEDNVNVAEILEKNGANIDMATK-AGYTPLHVASHF
G------------------QANMVRFLLQNGANVD---AATSIGYTPLHQTAQQGHCHIV
NLLLEHKANAN---AQTVNGQTPLHIARKLGYISVLDSLKTITK----EDET--AAAPSQ
AEEKYRVVAPEAMHESFMSDSEEEG--GEDNMLSDQPYRYLTVDEMKSLGDDSLPIDVTR
DERMDSNRMTQSAEYASGVPPTIGEEVISPHKTQVYGSSPKATVDGVYIANGSGHDEPPH
VGRKLSWKSFLVSFLVDARGGAM------RGCRHSGVRMIIPSRSTCQ----PTRVTCR-
------------------YVKPQRTMHPPQLMEGEALASRVLELGPCSTKFIGPVVMEVP
HFASLRGKEREIIILRSDNGETWREHTIDNSEEIIHDVLQQCFEPEEIAQLEEQAGNHVC
RFVTYDFPQYFAVVSRIRQEVHAIGPEGGMVSSTVVPQVQAVFPQGALTKKIKVGLQVNL
FKPRKGVAPEKLRKISVNHVPKKKRFSLIW
>gi|115753797|ref|XP_001193298.	Strongylocentrotus purpuratus
--------------------MTPLNIAARYDDLHDTNNLISQGAEGDNDGWTALHVAAHE
GRLDVTKYLTSQGA---QGDNDGWTALHNAAHEVYLDITKCLISQGAE------------
------------------------------------------------------------
--------------------VNKGDN--DGWTAL-HVAAQKGHLEVLKYHIDHGAEVNKG
DNDAEVNRE---------------------------------------------------
------------------------------------------------------------
-------------------------------------------------NNDGRTALHVA
ARNGRLDVTKNLTTQGVEVNKGD------NDGITALHSAAQKGHLDVTKCLVTQRAEVNK
GRNDGRTALHSAAQEGHLDVTKYLITQGAELN---KGDNDGRTALHSTAQEGHLDIAKYL
TSQEAEVNRENNDGRTALHVAAQKGRLDVTKHLIRQGVDVNTGDNDGITALHTEVNKGRN
DGWTALHSAAHEGHLEVTKYLISQGAEVNKGRNDGWPALNSAAQEGHLDVTKCLITQGAE
EGHLDVTKYLITQGAELNIGDNDGRTALHSAAQEGHLDITKCLITQGAEVNKGRN----D
GWTALNSAAQEGHLDVTKYLINRGAEVNRENNDGRTALHVAARNGRLDVTKNLTTQGVEG
HLDVTKCLVTQRAEVNKGRNDGRTALHSAAQEGHLDVTKYLITQGAELNKGDNDGRTALH
STAQEGHLDIAK--YLTSQEAEVNRENNDGRTALHVAAQKGRLDVTKHLIRQGVDVNTGD
NDGITALHSAAQKGHLDVTKYLIGQGAEVNKGDNDGWTALYTAAQDGHLDVTRYLITQ--
--------GAEVNKGRNDGWTALHSAAHEGHLEVTKYLIS-----QGAEVNMGRNDGWTA
LHSAAHEGHLEVTKYLISQGAQVNKGDNDGWTALHVAAQKGH-FEVTKYLICQGAEVNNG
DNDGWTALYTAAQEGHLDVTNYLISQGAEV---------------NNGDNDGWT------
------------------ALHVAAQNDHLDVTKHLISQGAEVNKGDN-DGRRALYAAVQE
S------------------HLDITNYLISQGAEMNEGDNEDNEGRNSLHSAAQKGFFDVT
KYLISQGAEVN---RGDNKGGTALHSATQKGLLDVTKYL--ISQGA--EMNR--GDIEGK
TVLHSAAQEGHLGVTKYLLALGISVNIVDRNGSTPLHNAAMNGDFDIVKVLLEEGALVDV
KDVNGQNPLHLSSKKGNPDSSDSLAKHAKITGILDDRDDDGLTAIHLATQNGHTPVVESL
VSHGASLNIRSHKGKTCLHEAITLSDHEDRKEQTQGKSKQISEDFYQQ---ELSPEKALV
LYLLEHGAKLDIRDGEGKLPVHYATNEVFRQMIFSKGTTEAEENDYD--KLPEMA-----
----------------QSDGTDDVEQVNHALDGSYASGKFGALGGKLSTKSHGFTLHIPP
GALEEDEKISLRVLTEIPNGLTLKEDELLVSHGFKCYPSGLRFKKPAKLIIPHCALVTAP
NK----------------------------
>gi|110757319|ref|XP_395446.2|	Apis mellifera
MMPGTSRQLGTSNGGPEWDTLMEVHHEPIEKNYKLLEEIGKGQFAIVRKCMEIKTGEFYA
AKIMRKRRVA---RGVAAADIAREAGLLARLRHPNIVSLHKVVDTGTTVVLLLELISGGE
LFHWVPSGEL----EAAHVVRQVLMALSHLHSHQVAHLDIKPENI-LLSTPPPMPSIKLI
DLGLSHRLVPGSEHRALFGTPEFVAPEIVNYEPL-SLGTDLWAVGVLTYILLSGASPFLG
EDKQETYANVAACQYQFDNEYFSTVSEIAKDFIRSLLIKDPKERGTAESCLKHPWILTES
E-----------------------------------------------------------
------------------------------------------------------------
---------------------AS------QGLGGAMISAVKRGCVEAVSQLLLQGAPLNV
KDSKEDTLLHIACEAGDEGMVTFLIENGIDLD---TPNKKGLTPLHVAARYGFINLVRHL
CLAGCDVDKTNR------------------------------------------------
------------------------------------------------------------
-G----------------------------------------------------------
----------------------IRADVTAIK---------------------------YG
HPDIASLLDK----LRNPIQRENYIKQLQPTHRPIDRLHIRLLGHC------ASGKSSLI
NSLKSGIFSFG---FFRRSRSQNYTAKREP----------------------SIELDVTS
KHGSLSFEY--------------------SDSEYEGTQGVEWSRGNVGGECIFWELCGRE
EFLASYHYVLTFQQPAVHLITVSLREPLTVQLQQVKFWLRFIS--DRIASTNFGFGGKYN
DLKVILVGTYAPEPLAPNSNS-----GSLLAPLLPFLKEFTPILGDEPQMVAVDATNPSS
PGLKLLRSYLNNARMEFLESALV----------------------WTGLAESWRSYMQSL
EVPPVMLTQEEFLKEVR-KINPLVSLEHCRHLGLQLQNLGECML----LPGNLIVLSPEW
F------------------WQDVINW--QLSLEQRGRLGGRTTGVYALEDFQARCPCPAG
QAL-QALQAVNLCVPCEVDDDEVEY------EIPCLNLVERLPGLW--EPWKPCSNVLPH
TGLRLCPSEAPLYHLIAIFPHLQAQ--LRKITQTWDPS-------NSDLYQWWRGSKLCI
GPCESIITFEEEEQS--CIEIRVRGPRGTSAQCFALFSIILDAIETTIELVAPGMLLERY
WLSPSQLREYDEIIYSWEPTSIISAL---IDKGLEEATLKNPLNSREE---SIWEIVGC-
------------------GLPLIENCLPGPKQP-IKQIKAAVQRRLA--QMLDPP-----
----------------DRHGRDWCLLAV-RLGLGDRVAQ-------------LDSTVDSP
TLRLINTAGADCTVGSLIQQLRALDREDAVHLLLSYTPTYILSTTTDSETGSNLSR----
------------------------------
>gi|148709352|gb|EDL41298.1|	Mus musculus
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
--RQGKTMPLRRTRYGHADVGQLLCSFGSNPD---FQDKEEETPLHCAAWHGYYSVAKAL
CEVGCNVNIKNREGETPLLTASARGYHDIVECLAEHGADLNASDKDGHIALHLAVRR---
------------------------------------------------------------
-CQMEVIKTLLGHGSFVDFQDRHGNTPLHVACKDGSAPIVVALCEASCNLDISNK----Y
GRTPLHLAANNGILDVVRYLCLMGANVEALTSDGKTAEDLAKA---------------EQ
HEHVAGLLAR----LRKDTHRGLFIQQLRPTQNLQPRIKLKLFGHS------GSGKSTLV
ESLKCGLLRS----FFRRRRPRLSSTNSTRFPPSPLAAKPTVSVSINNLYPGCENVSVRS
RS--MMFEPGLTKGMLEVFVAPSHHLHCSTDDQSTKAIDIQNAYLNGVGDFSVWEFSGNP
VYFCCYDYFAANDPTSIHIIVFSLEEPYEIQLNQVIFWLSFLKSLVPVEEPIAFGGKLKN
PLRVVLVATHADIMNIPRPAGGEFGYDKDTSLLKEIRNRFGNDLHVSNKLFVLDAGASGS
KDIKVLRNHLQEIRSQIVSGCSPMTHLCEK---------------IISTLPSWR----KL
NGPNQLMSLQQFVYDVQDQLNPLASEDDLRRIAQQLHSTGEINIMQSETVQDVLLLDPRW
L------------------CTNVLGKLLSVETPRA---LHHYRGRYTMEDIQRLVPDSDV
EELLQILDAMDICARDLSSGTMVD--------IPALIKTDSLQRSW--ADEE--DEVMVY
GGVRIVPVEHLTPFPCGIFHKVQVN--LCRWIHQQSAEG------DADIRLWVSGCRIAN
RGAELLVLLVNHGQG---IEVQVRGLETEKIKCCLLLDSVCSTIETVMATTLPGLLTVKH
YLSPQQLREHHEPVMVYQPRDFF------RAQTLKESSLTNTMGGYKE---SFSSITCF-
------------------GCHDVYSQASLGMDIHASDLSLLTRRKLS--RLLDPP-----
----------------DPMGKDWCLLAM-NLGLPDMVAKHNVNNRASR----DFLPSPVH
ALLQEWTSYPESTVGILISKLRELGRRDAADFLLKASSVFKINLD--GNGQEAYASSCNS
GTSYNSISSVVSRRDSHAWTPLYDL-----
>gi|119583130|gb|EAW62726.1|	Homo sapiens
--------------------MTVFRQENVDDYYDTGEELGSGQFAVVKKCREKSTGLQYA
AKFIKKRRTKSSRRGVSREDIEREVSILKEIQHPNVITLHEVYENKTDVILILELVAGGE
LFDFLAEKESLTEEEATEFLKQILNGVYYLHSLQIAHFDLKPENIMLLDRNVPKPRIKII
DFGLAHKIDFGNEFKNIFGTPEFVAPEIVNYEPL-GLEADMWSIGVITYILLSGASPFLG
DTKQETLANVSAVNYEFEDEYFSNTSALAKDFIRRLLVKDPKKRMTIQDSLQHPWIKPKD
TQQALSRKASAVNMEKFKKFAARKKWKQSVRLISLCQRLSRSFLSRSNMSVARSDDTL--
-----------DEEDSFVMKAIIHAINDDNVPGLQHLLGSLSNYDVNQPNKHGTPPLLIA
AGCGNIQILQLLIKRGSRIDVQD------KGGSNAVYWAARHGHVDTLKFLSENKCPLDV
KDKSGEMALHVAARYGHADVAQLLCSFGSNPN---IQDKEEETPLHCAAWHGYYSVAKAL
CEAGCNVNIKNREGETPLLTASARGYHDIVECLAEHGADLNACDKDGHIALHLAVRR---
------------------------------------------------------------
-CQMEVIKTLLSQGCFVDYQDRHGNTPLHVACKDGNMPIVVALCEANCNLDISNKLSSQY
GRTPLHLAANNGILDVVRYLCLMGASVEALTTDGKTAEDLARS---------------EQ
HEHVAGLLAR----LRKDTHRGLFIQQLRPTQNLQPRIKLKLFGHS------GSGKTTLV
ESLKCGLLRS----FFRRRRPRLSSTNSSRFPPSPLASKPTVSVSINNLYPGCENVSVRS
RS--MMFEPGLTKGMLEVFVAPTHHPHCSADDQSTKAIDIQNAYLNG-------------
------------------------------------------------------------
------------------------------------------------------------
-------------------------------------------------MPSWR------
------------------------------------------------------------
------------------------------------------------------------
--------------------------------------------------FQ--RVGVLW
KS----------------------------------------------------------
--------------------------------CVFLLL----------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------
>gi|47221525|emb|CAG08187.1|	Tetraodon nigroviridis
----------------------------------------SGQFAVVRRCRHRSTGVEYA
AKFIKKRRSKSSRRGVSREDIEREVNILKEIQHANIITLHEVFENKAE------------
-----------------------------------------PENIMLLNRSVPHPRIKII
DFGLAHKIDFGNDFKNIFGTPEFVAPEVVNYEPL-GLEADMWSVGVITYILLSGASPFLG
DNKQETLANVSAVDYTFDEEFFSNTSILAKDFIARLLVKDPKKRMAIQDSLQHPWIKPKD
TQQALSRKESAVNMEKFKKFAARRKWKQSVRLISLCNRLSRSFLSRSNISVARSDDTLQS
ITADLCAVLLQDEEDSFVMKAIIHAINDDNVPGLTHLLGSLNSYDVNQPNKHGIPPLLIA
AGCGNIQIIEVLMRKGAEIQAGD------KSGANAIYYAARHGHVDTLKFLHEKNCPLDI
QDKSGETALHVAARYGNVDVVGYLCSIRANPD---LADREQETPLHCAAWHGYSTVARAL
CQAGCRVDAKNREGESPLLTASAR------------------------------------
------------------------------------------------------------
-GFVDIVECLVEHRANLETCDK--------------------VINHECC----------F
PLMTMDTQPSTWPYGGVRLKCMAGLLFTWLPAMGAWRWFVT-----------------CV
WLELTLTLSP---------------ISCGPLRPSSPGIKLKLFGHP------GAGKSTLL
ESLKCGILRS----FFRRRRTRM--TNTARQPNSPVNSKPPVSVSISNLYPGCENVSVRS
RS--MMFEPSLTKGVLEVF-SPVHSTLSTADEQATKAIDIQHANIHSVGDFSVWEFSGNP
VYYCSYDYFAANDNTAIHLVLFSLEEPYETQLSHVTYWLNLLKALTLPQDNIGFGGRIQQ
PLLVVLVATHADLADIPRAFSGEFTYDKEKVLLKEVRNRFGLDLQISEKLFVMDAGASNS
KDLKLLRSHLLELRSSIISKCSPMTQLTER---------------LLNTLPAWR----KL
SGPNQLTSWQQFVSDVQEHINPLVSQDHLRALTMQLHSMGEINIMQSETVQDVVLLEPRW
L------------------CSSILGKLLSVETPKA---IHHYRGRYRLEEVQALVPESDV
EELLQILDAMDICARDTTNPFMVD--------VPTLIKTSGLHRSWTEEDEE--DEALIY
GGVRLVPAEHLTPFPCGLFHKLQVN--LCRWSHQQKSEEEGGDDFDGDIHLWTNGAKVSQ
TGVEALVLLVNHGQG---VEIQVRGHDSERAKCYTLLDTICSITENLLTSTLPGLLTAKY
YLSPQQLRERHTPIMIYQPKDFF------RAQAQRETSLTNTMGGYRE---SFSSILSF-
------------------GCAEVYQQGTLGTDVHISDVPLLARRKLC--RMLDPP-----
----------------DAMGKDWCLLAM-NLGLTELVAKHSNGTSNGAAEPDSPQPSPTA
ALLQEWSGRADSTVGVLMGKLRELGRRDAADFLLKASPVFRVNVEAIGRAANGYPPICNG
GTSYNSISSVISR-----------------
>gi|149723050|ref|XP_001500798.	Equus caballus
------------------------------------------------------------
------------------------------MSQQDA--VAALS-----------------
------------------------------------------------------------
-------------------------------ERL-LIAAYKGQVENVVQLINKGAK----
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-----VAVT--------------------KHGRTPLHLAANKGHLSVVQILLKAGCDLDV
QDDGDQTALHRATVVGNTEVIAALIQEGCALD---RQDKDGNTALHEASWHGFSQSAKLL
VKAGANVLAKNKAGNTALHLACQN------------------------------------
------------------------------------------------------------
-SHSQSTRILLLGGSRADLKNNAGDTCLHVAARYNHLSIIKLLLSAFCSVHEKNQ----A
GDTALHVAAALNHKKVVKILLEAGADGTIVNNAGQTPLETARY---------------HN
NPEVALLLTKAPQVLRFSRGRSL----------RKKRERLKEERRAQSVPRDEVAQSK--
GSVSAGDTPSSEQAAPRKEEPREDFLSASPEPRAK----------------DNRQRKSRP
KA--SAFS----------------DPTPPADQQPGHQKNLHTHNHPKKKARH--------
--------RCSPPPPPHEFRAYQLYTLYRGKDGKV----------MQAPIDGCRCEPLIN
KLENQLEATVEEIRAELGSVQ-----DKMNTKLGHMESKTQHQMRVLDKLMVERLSAERT
ECLNRLQLHSDTEKQEGEKRQMS----------------------LVDELKTWC------
---------------------------MLKIQNLELKLSGDSRASR--TKSTPSTCESST
G--------------------------VDQSVVTAGPVAASDTSPQVVRPKEKALNATAT
HRLQQEL-------------SSSDCTGSRLRNVKVQTALLPLKEAA--KCDQ--QAGP--
------------------------------------------------------------
--------------------------------CVD-------------------------
-----------------------------RGTQTKKSGKSGQTRHRAQ---QPAPAASC-
------------------GPPP--AAGSEQTAPHLRDTSQALEITQY---FFEAV-----
----------------STQMEKWYERKI------------------------EEARSQAS
QKAQQDKATLKEHIKSLEEELAKLRTKVQKEN----------------------------
------------------------------
>gi|149039748|gb|EDL93864.1|	Rattus norvegicus
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
----------MPPRYGHADVVQLLCSFGSNPD---FQDKEEETPLHCAAWHGYYSVARAL
CEVGCNVNIKNREGETPLLTASARGYHDIVECLAEHGADLNASDKDGHIALHLAVRR---
------------------------------------------------------------
-CQMEVIKTLLGHGCLVDFQDRHGNTPLHVACKDGSAPIVVALCEASCNLDISNK----Y
GRTPLHLAANNGILDVVRYLCLMGANVEALTLDGKTAEDLAKA---------------EQ
HEHVAGLLAR----LRKDTHRGLFIQQLRPTQNLQPRIKLKLFGHS------GSGKSTLV
ESLKCGLLRS----FFRRRRPRLSSTNSTRFPPSPLATKPTVSVSINNLYPGCENVSVRS
RS--MMFEPGLTKGMLEVFVAPSHHLHCSTDDQSTKAIDIQNAYLNGVGDFSVWEFSGNP
VYFCCYDYFAANDPTSIHIIVFSLEEPYEIQLNQVIFWLSFLKSLVSVEEPIAFGGKLKN
PLRVVLVATHADIMNIPRPAGGEFGYDKDTSLLKEIRNRFGNDLHVSNKLFVLDAGASGS
KDIKVLRNHLQEIRSQIVSGCPPMTHLCEK---------------IISTLPSWR----KL
NGPNQLMSLQQFVYDVQDQLNPLASEDDLRRIAQQLHSTGEINIMQSETVQDVLLLDPRW
L------------------CTNVLGKLLSVETPRA---LHHYRGRYTMEDIQRLVPDSDV
EELLQILDAMDICARDLSSGTMVD--------IPALIKTDSLQRSW--ADEE--DEVMVY
GGVRIVPVEHLTPFPCGIFHKVQVN--LCRWIHQQSTEG------DADIRLWVSGCRIAN
RGAELLVLLVNHGQG---IEVQVRGLETEKIKCCLLLDSVCSTIETVMATTLPGLLTVKH
YLSPQQLREHHEPVMVYQPRDFF------RAQTLKESSLTNTMGGYKE---SFSSITCF-
------------------GCHDVYSQASLGMDIHASDLSLLTRRKLS--RLLDPP-----
----------------DPMGKDWCLLAM-NLGLPDMVAKHNVNTRASR----DFLPSPVH
ALLQEWTSYPESTVGILISKLRELGRRDAADFLLKASSVFKINLD--GNGQEAYASSCNS
GTSYNSISSVVSR-----------------
>gi|109072030|ref|XP_001097628.	Macaca mulatta
------------------------------------------------------------
------------------------------MSQQDA--VAALS-----------------
------------------------------------------------------------
-------------------------------ERL-LIAAYKGQTENVVQLINKGAK----
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-----VAVT--------------------KHGRTPLHLAANKGHLPVVQILLKAGCDLDV
QDDGDQTALHRATVVGNTEIIAALIHEGCALD---RQDKDGNTALHEASWHGFSQSAKLL
VKAGANVLAKNKAGNTALHLACQN------------------------------------
------------------------------------------------------------
-SHSQSTRVLLLAGSRADLKNNAGDTCLHVAARYNHLSIIRLLLSAFCSVHEKNQ----A
GDTALHIAAALNHKKVAKILLEAGADTTIVNNAGQTPLETARC---------------HN
NPEVALLLTKAPQVLRFSRGRSL----------RKKRERLKEERRAQSVPRDEVAQSK--
GSVSAGDTPSSEQAVARREEAREEFLSASPEPRAK----------------DDRRRKSRP
KV--SAFS----------------DPTPPADQQPGHQKNLHAHNHPKKRNRH--------
--------RCSSPPPPHEFRAYQLYTLYRGKDGKV----------MQAPINGCRCEPLIN
KLENQLEATVEEIKAELGSVQ-----DKMNTKLGQMENKTQHQMRVLDKLMVERLSAERT
ECLNRLQQHSDAEKHEGEKRQIS----------------------LVDELKTWC------
---------------------------MLKIQNLEQKLSGDSRACR--AKSTPSTCESST
G--------------------------VDQSVVTAGPAAASDSSPPVVRPKEKALNSTAT
QRLQQEL-------------SSSDCTGSRLRNVKVQTALLPMNEAA--RSDH--QAGP--
------------------------------------------------------------
--------------------------------CVN-------------------------
-----------------------------RGTQTKKSGKSGPTRHRAQ---QPTASSTC-
------------------GQPP-PAAGGEQTGPHIRDTSQALELTQY---FFEAV-----
----------------STQMEKWYERKI------------------------EEARSQAN
QKAQQDKATLKEHIKSLEEELAKLRTRVQKEN----------------------------
------------------------------
>gi|35903137|ref|NP_919404.1|	Danio rerio
------------------------------------------------------------
------------------------------MSQRDASCVRALS-----------------
------------------------------------------------------------
-------------------------------ERL-LIASHKGQADHVVQLINRGAK----
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-----VAIT--------------------KNGRTPLHLAAYKGHIAVVRILLAAGCDLDI
EDDGDQTALHRAAVVGNTDVISALVQEGCALD---RQDKDGNTALHEAAWHGFSQTVKLL
VKAGANVHAKNKAGNTALHLACQN------------------------------------
------------------------------------------------------------
-GHVQSCRVLLLGGSRPDSKNSVGDTCLHVSARYNHVSVIRALLGAICSVTDRNH----T
GDTALHIAASLNHRKTVRMLLEAGADSRIKNNTGETALDQARE---------------NN
SPEVALLLTKAPAELQSRTHR------------EERRDKMKTEGRAQSVPRDEMLPRKCD
SASPAQDTHGSDGSLRRTDNMFLTEPRAN----------------------KNCHRKARD
RL----------------------SPSDALIYRPNKQSDPKKKSKTERSSP---------
--------SAVPPPPPHNYKAYQLYTLYRGKDGKI----------MQAPLNGCRCEPLIS
KLENQLMATKEEMQSEIHTVQ-----ELMNSKIGQMDRKSKHQIRALDKMTLERVSAERI
ECLHRIDKRAVQERLEAEKRQTS----------------------VVKDLKNWC------
---------------------------LSKIQSLETRLSGERVGSR--LQRSSSLTDTLS
D------------------CTPVLE--PSRAAPSPSPSAEPTDARETAAASSCAEDAPAR
YYVIEVDASADKPSSQNQSAPQSPCIVRPKQRSRACSDPHQLRD----ESEE--------
------------------------------------------------------------
------------------------------------------------------------
-----------------------------RSVEARPSAEHRTIRRHRA---KSKPSAQS-
------------------LTLQTCPAAAEGAFAQERDNMHALEVTQY---FFEAV-----
----------------TLQMERWYEREI------------------------EETRRQAD
HRVQADRELLLDRIQHLEDELRLLRMNTQDG-----------------------------
------------------------------
>gi|73973471|ref|XP_853842.1|	Canis familiaris
------------------------------------------------------------
------------------------------MSQQDA--VAALS-----------------
------------------------------------------------------------
-------------------------------ERL-LIAAYKGQAENVVQLINKGAK----
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-----VAVT--------------------KHGRTPLHLAANKGHLSVVQILLKAGCDLDV
QDDGDQTALHRATVVGNTEVIAALIQEGCALD---RQDKDGNTALHEASWHGFSQSAKLL
VKAGANVLAKNKAGNTALHLACQN------------------------------------
------------------------------------------------------------
-SHSQSTRVLLLGGSRADLKNNAGDTCLHVAARYNHLSIIKLLLSAFCSVHEKNQ----A
GDTALHVAAALNHKKVVKILLEAGADGTIVNNAGQTPLETARY---------------HN
NPEVALLLTKAPQVLRFSRGRSL----------RKKRERLKEERRAQSVPRDEVAQGK--
GSVSAGDTPSSEQAVPRKEEAREDFLSASPEPRAK----------------DNRQRKSRP
KV--SAFS----------------DPTPPADQQPGHQKNVHAHNHPKKRARH--------
--------RCSPPPPPHEFRAYQLYTLYRGKDGKV----------MQAPINGCRCEPLIN
KLENQLEATVEEIKAELGSVQ-----DKMNTKLGHMENKTQHQMRVLDKLMVERLSAERT
ECLNRLQQHSDAEKHEGEKRQMS----------------------LVDELKTWC------
---------------------------MLKIQNLELKLSGDSRASR--TKSTPSTCESST
G--------------------------MDQSVVTAGPVAASDSSPQVVRPKEKAFSSTVP
HRLQQEL-------------SSSDCTGSRLRNVKVQTALVPLKEAT--KCDQ--QAGP--
------------------------------------------------------------
--------------------------------CVD-------------------------
-----------------------------RGTQTKKSGKSGQTRHRTQ---QPAPSNTC-
------------------GPPP-PAAGSEQTAPHVRDTSQALEITQY---FFEAV-----
----------------STQMEKWYERKI------------------------EEARSQAS
QKAQQDKATLKEHIKSLEEELAKLRTKVQKEN----------------------------
------------------------------
>gi|115398530|ref|XP_001214854.	Aspergillus terreus
-------------------------------------------------MDPVSAFGVVS
GAFQVAQIITQTAA--------GLWSLREKYAHADL-TIRSLVGELTT------------
------------------------------------------------------------
--------------------IKSAITQLDDWARLQNTRSTAVTAEYTEY--DEGLNVAL-
------------------------------------------------------------
------------------------------------------------------------
---------------------------------------------------DGCRVVMDV
LSEEVASLTRGAAGTDAHIGFGTRLRAMWNEDVMRGHQERLRSQVVALQLLLQACQC---
RSSSEQIELLRRVENRRI-IRKVAEDAETLRS---SSSYAGSRADTASLSHRQFSVG---
-ETGFDFDTAATVSAPYRRALQPWSRTETLSTMSSGNDSRETDEGYG-------------
------------------------------------------------------------
-SMSQADSLILPIRPHESIGNSHSRS---VTLRPNRTQPNQSGMRRWKSDSTSSS-----
--QPTRSASKLSLRSTWRPWRRSNSTKSNAQLVQQIPTENVA----------------PG
RRSSRRDVTTSIDFASHEGSSAPAIVKAAQSGSREDVERLITSGHEIEARHIHSRRNALL
VASHCGNEAVVD--LLIQRNARLGATDASGWTALHLAASRGHCGVLELLLLEDVDIEART
SNGRTALWIAAEQGQVEAARILIENNAKVNTRADNHMTPLHVAAKVGDVATIELLVSS--
--------KADVEAKDGLMMTALHYACEGGHLGAIKALIN-----NKAKVDTLGSDRRTP
LICAAAMGQLEATQLLLKMKASERHADDASMTALHWAAFNGH-TEVVEILSQKKEALTIT
NIAGRTALHLAVMRSRFAVVELLLRKRTLV---------------EARCLSGMA------
------------------ALHYACMANNIEIARLLLLSGADIEVPTE-DQRRPIHIAAAC
G------------------SMAVLDLLCDKGASLE---ARDALGDRALCTACRHGHAAAV
QNLLNRGSPLYLQYDTRNKEDSPLCLAAMGGHLPVVNIL--LERGA--SVLK--RDEMGW
PPHYHAMHHGHPDVLRLLLARNPAE--VTAGALNLSQTMSRVGFSPVNISE-ARKREVHE
VLSQMQRSSAETGEAAPPLSSPWANDREISQRRPEYITVPRSLQDIPETNSTRHTPRPDY
PSGPQELPGTLEQGLPPSRS---------RTPEHLSGGVDSNAATHAEGSIVPAPASRE-
------------------GSSAWTNQIVMPRAQRPGLAGPVRQAPNN--PLPSTV-----
----------------LDLLEEWSQQRS-------------------TVSPVSVAPGQPP
APVE-NPPVGLSKLKNSPERLPIADRADESSDTDSMTSVHTAPEEAPVDMKL--------
------------------------------
>gi|115941422|ref|XP_001179377.	Strongylocentrotus purpuratus
--------------------------MSKEADL---------------------------
GRTDIVR-----------------TILLNASTEGDIYTVKYIIRKGAN------------
------------------------------------------------------------
--------------------PNSGND--DGYTPM-YIASREGHLDVVECLVNAGADVKK-
--------T---------------------------------------------------
------------------------------------------------------------
-------------------------------------------------AKNGATALDIA
LNRGHVGIVKYLISKGANPNLVQ------NDGYTHLHIASVQGNLDVVECLVNAGADVKK
AAKNGVTSLHTASSAGREDIVKYLISQGANPN---SIDNDGYTPLYIASREGHLNVVECL
VNAGADVNKAAKDGMTSLHAASYT------------------------------------
------------------------------------------------------------
-GHGDIVSYLISQGAKPNSVDNHGYIPLHIASVQGHLYVVECLVKAGADVKKAAN----D
GMTSLDIALKIGHVDIVKYLISQGANPNSIDNDGYTPLYIASR---------------EG
HLNVVECLVNAGADVNKAAKDGMTSLHAASYTGHGDIVNYLISQGAKLNSVDNHGYTSLY
GASKEGHLDVVE--CLVNAGADVNKAAKDGMTSLHAASYTGHGDIVSYLISQGAKPNSVD
NHGYTSLYGASQEGHLDVVECLVNAGADVNKAAKDGATSLHTASYTGHGDIVNYLISQ--
--------GAKPNSVDNHGCTSLYIASQEGHLDVVECLVN-----AGADVNKAAKNGMTS
LHMASYTGHGDIVNYLVSQGANPNSVYNDVNIPLEIASQEGH-IDVVKCLVNAGAGVNKA
AKKGVTSLHTASYGGHVDIVNYLISQGANP---------------NSVDNHGYT------
------------------SLYVASQEGHIDVVKCLVNAGADVNKAAK-NGVTSLHTASYT
G------------------HGDIVNYLISQGANPN---SVDNHGCTSLYIASREGYLQCV
ECLVNAGGDVN---KPAIDGDLPLHAASRGGYIDILKYL--IMKGG--DIEA--RNNFGW
TVFHFAADNGHLESLEIF------------------------------------------
------------------------------------------------------------
-----------------------------LEKQHLHRGQLPPGRNWET------------
----------------------------------LQGVTPLMAAARG--GHLDCV-----
----------------RLLLENNADIET--------------------------------
VDAEGWTSVHYAAAR---------------------------------------------
------------------------------
>gi|114608474|ref|XP_001158857.	Pan troglodytes
------------------------------------------------------------
------------------------------MSQQDA--VAALS-----------------
------------------------------------------------------------
-------------------------------ERL-LVAAYKGQTENVVQLINKGAK----
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-----VAVT--------------------KHGRTPLHLAANKGHLPVVQILLKAGCDLDV
QDDGDQTALHRATVVGNTEIIAALIHEGCALD---RQDKDGNTALHEASWHGFSQSAKLL
VKAGANVLAKNKAGNTALHLACQN------------------------------------
------------------------------------------------------------
-SHSQSTRVLLLAGSRADLKNNAGDTCLHVAARYNHLSIIRLLLTAFCSVHEKNQ----A
GDTALHVAAALNHKKVAKILLEAGADTTIVNNAGQTPLETARY---------------HN
NPEVALLLTKAPQVLRFSRGRSL----------RKKRERLKEERRAQSVPRDEVAQSK--
GSVSAGDTPSSEQAVARKEEAREEFLSASPEPRAK----------------DDRRRKSRP
KV--SAFS----------------DPTPPADQQPGHQKNLHAHNHPKKRNRH--------
--------RCSSPPPPHEFRAYQLYTLYRGKDGKV----------MQAPINGCRCEPLIN
KLENQLEATVEEIKAELGSVQ-----DKMNTKLGQMENKTQHQMRVLDKLMVERLSAERT
ECLNRLQQHSDTEKHEGEKRQIS----------------------LVDELKTWC------
---------------------------MLKIQNLEQKLSGDSRACR--AKSTPSTCESST
GNPHTESPFVQKEHDQQLLYSPALKGSVDQLVVTAGPAAASDSSPPVVRPKEKALNSTAT
QRLQQEL-------------SSSDCTGSRLRNVKVQTALLPMNEAA--RSDQ--QAGP--
------------------------------------------------------------
--------------------------------CVN-------------------------
-----------------------------RGTQTKKSGKSGPTRHRAQ---QPAASSTC-
------------------GQPP-PAAGSEQTGPHIRDTSQALELTQY---FFEAV-----
----------------STQMEKWYERKI------------------------EEARSQAN
QKAQQDKATLKEHIKSLEEELAKLRTRVQKEN----------------------------
------------------------------
>gi|121703574|ref|XP_001270051.	Aspergillus clavatus
-------------------------------------------------MDPFSWIGAIS
GVLQITQVISQTAI--------GLSKLKGKFDNADL-TIQCLIGELAT------------
------------------------------------------------------------
--------------------IKSAVTHLEDWARF-NVRDTTESEEYI-----EGLNVAL-
------------------------------------------------------------
------------------------------------------------------------
---------------------------------------------------DGCRAVMEH
LGDEVTSLTQTVTGQATVIGFRARVKVIWNEDVMRGHQERLHAQVVALQLLLQACQCRYS
RSSSEQVELLRRAENRQ--IIQKVAYDTATLR---GSSYAGSRVLSSNWSFYQPSISQAA
ADVDRTFAESPSFHRPLPHLRSKSESWSSASQKGDYERDTDEGYASGATASP--------
------------------------------------------------------------
-SLSQTNSVSLPIRSYNSMILGNGHSKSMTYGSAPGRQLSQTQVQRSHSSTNPPL----S
PQSPLGSKRGSVVRSMLRRFSRSNLTSSALSSPARSLTASK-----------------TT
RAMSKKDLEPSIDLASPEGAAAPMIVKLAQSGSRPDVEMLIESGHGVDSRHFSTRRTALL
VAAHCGHESVVD--LLIQKRARLDVVDAGGSTALHLAASRGHCNVLRLLL-EHSMTEVCD
AHGRTALWVAAHRGQLEALRLLIANHARVNVRADNHMTALHTAAKRGDEAIIELLIAC--
--------GADIEAKDGAMMTALHYACEEGHLGAIRLLLD-----GKATIDALGSDRRTP
LICAAAMGRFAATQELLKRKASVRSGDDASMTALHWAAFNGH-TEVVELLSRKKGALAEC
NKLGRTALHLAAMNSRFAVVESLLRMSIPV---------------ETRCLDGLT------
------------------PLHYACLANNLEIVRLLLISDADVEAQTDTDQRRPVHIAAAH
G------------------SMGLLNLLIDKGASLE---ARDSMGDRALGVACRYGHAAAV
QNLLGRGCPLYLKFGDKSQEDSPLCLAAMGGHLPVVSLL--LQHGA--SVVK--KDGFGW
QPHHYAAYNAHPDILALLLSHGPVS--------ASDGTEFGQDASRIGFAPHAGISEEQK
EQIRGLLHRDGTQLEGQTQNMTFQGTQPIVGTCNDTPGVPSIHVQAQPTHSSTAISAV--
--APQELPVTLEQGLPASRSA--------TPEHMRRGGALDSGRIGNP------------
------------------GDSSQMISFEPVGAQSDGGFPPSFYSMPY--WRGTPV-----
----------------SAVHKREAEVEV-------------------------LAPEPTG
GPTSRSPNPRFTSFVTTFDAVNSAGDLASDTDSESSSSVYTAPES---------------
------------------------------
