>gi|109508008|ref|XP_341677.3|	Rattus norvegicus
------------------------------------------------------------
---------------------------MLTAHWLSKADLVALL--------------PAP
SDTIAAPSKMAAATADPGAGN-PQAGDSSGGDSGGGLP----------------------
-----------SPGEQELS----------------RRLQRLYPAVNQHETPLP--RSW--
SPKDKYNYIGLSQGNLRVHYKG-HGKNH-KDAA-SVRATHPIPAACGIYYFEVKIVSKGR
DG----------YMGIGLSAQ--GVNMNRLPGWDKHSYGYHGDDGHSF--CSSGTGQPYG
PTFTTGDVIGCCVNLINGTCFYTKNGHSLGIAFT----DLPA-NLYPTVGL-QTPGEIVD
ANFGQQPFLFDIEDYMREWRTKVQGTVHGFPISARLGEWQ--AVLQNMVSSYLVHHGYCA
TATAFARMTETP-----------------IQEEQASIKNRQKIQKLVLEG-RVGEAIETT
QRF------YPGLLEH--SPNLLFMLKCRQFV-------------EMVNGTDSEVRSLSS
RSPKSQDSYPGSP------SLSPRHGPS--------SSHIHNTGADSPSCSNGVASTKNK
QNHSKYPAPSSSSSSSSSSSSSSPSSVNYSESN-STDSTKSQPHS-------STSNQETS
DSEMEMEA-EHYPNGVLA-------SVSTRIVNGAY------------KHDDLQTDES--
----SMDDGH----PRRQLCGGNQAATERIILFGRE---------LQALSEQL------G
REYGKNLVHTEMLQDAFSLLAYSD--------PWSCPVGHQLDPIQREPVCAALNSAILE
SQNLPKQPPLMLALGQASECLRLMARAGLGS-CSFARVD-DYLH-------
>gi|108882110|gb|EAT46335.1|	Aedes aegypti
------------------------------------------------------------
-----------MTAFEEFGVMPEIGKAIDEMEWM--------------------------
---LPTDVQAEAIPLILGGGD-VLMAAETGSGKTGAFC----------------------
--------LPILQIVWETL----------------RDIREGKAGKAVGNMGKP----WTL
SFTDRGNAMAVTPDGLRC-----QSREF-KEWH-GCRATTGVRGK-GKYYYEATVTDEG-
------------LCRVGWSTE--IANLD--LGTDKFGFGFGGTGKKSN--CKQFD--SYG
EAFGKMDVIGCMLDLDRGEVSFTKNGTSLGLAFKINDAKMRESSFFPAVVL---KNAEMS
FNFGETDFKYAIPDGFVAVCKVPHDYLAVNPNTGSEAAVD---SKPKPNAPQAI---VIE
PSRELAEQTFNQ-----------------IQKFKKYLKDPEVRELLLIGGVNIKDQMEVL
QRGVDIIVGTPGRLEDLIGNGYVLLSGCRFFVLDEADGLLKQGYTELIERLHKQIPKITA
DGRRLQMVVCSATLHSFEVKKLAEKLMHFPTWVDLKGEDAVPETVHHVVCMVDPQKDNSW
QSLRS---HIQTDGVHARDNVRPGSNTAETLSE-AVKMLKGEYTLNAINEHNMDRAIIFC
RTKLDCDNLERYLRQVGG------NKYSCVCLHGDRKPQERKANLEKFKNKQVKFLICTD
VAARGLDVTGLPFIINVTLPDEKSNYVHRIGRVGRAERMGLAISLVSTVPEKVWYHGQWC
ASRGKNCWNTNLTDVKGCCMWYDEKMYLAEIEDHLNVTIQQIDKNLKVPMNDFDGKVVYG
EKRLNTGTGYKDHVEQLTPVVKELAKLEREAQNLFLKRM--TVQ-------
>gi|148725878|emb|CAN87952.1|	Danio rerio
------------------------------------------------------------
------------------------------------------------------------
-------------MAELGAGS-LLTGDPA-------------------------------
----------FNYQEHELN----------------ERLKRLYPAVNEEETPLP--RSW--
SPKDKYSYIGLSQNNLRVHYKG-HGKNH-KDAA-SVRATHPIPAACGIYYFEVKIVSKGR
DG----------YMGIGLSAQ--GVNMNRLPGWDKHSYGYHGDDGHSF--CSSGTGQPYG
PTFTTGDVIGCCVNLINNTCFYTKNGHSLGVAFT----DLPP-NLYPTVGL-QTPGEIVD
ANFGQQPFVFDIEDYMSEWRAKIHSMIARFPIGERLGDWQ--AVLQNMVSSYLVHHGYCA
TAMAFARATETM-----------------IQEDQTSIKNRQRIQKLVLAG-RVGEAIDAT
QQL------YPGLLEH--NPNLLFMLKCRQFV-------------EMVNGTDSEVRCFSV
RSPKSQDSYPGSP------NMSPRHGAT--------NPHLHSTGADSPTCSNGVTPPNKN
KSHNKY----TGISSASSSPSSSPSSVNYSESN-STDSTKSQPHS-------ATSNQETS
DSEMEIEA-EHYSNGVTE-------S-STRIMNGTY------------KHQEILQADDNS
VGNGVADDTC----SSRQLCGGNQAATERMIQFGRE---------LQTLSEQL------C
RQYGKNATHKKMLQDAFSLLAYSD--------PWNCPVGQQLDPMQREAICSALNSAILE
SQNLPKQPPLMLALGQATECVQLMARVRSGS-CSFARVD-NFLH-------
>gi|83774229|dbj|BAE64354.1|	Aspergillus oryzae
---------------MTDAPFPPSGGARGA--PVTTTYSGPSISTIPRRSSYASVLSGTA
-LSPPSNS-GPFSQLLTSNST-SYPPPFHPDGRHLRPSADV-DADMQMNSSWR----MSS
GDTLPPYSRKYASFTRSDPFP-PNPGSFSDAASSSFTPSYLRNSRYISRLDAARRAKLAS
QRDTVYSSSTSNPISTSSSQASLPRIAPSHRGMTYDIIEREPPGDDEHVMPLP--SRW--
NDGDKYSGLELTSGGLEVRYTGPVNKHD-HEAA-AVRADNPMPPQCGIYYFEITILSKPK
EG----------MIGIGFSSN--KASVERLPGWEQESWAYHGDDGKSFFGESQGQGRQYG
PTFGVNDTVGCGVNFSTGCAFFTKNGVFLGNAFR----ELRNLKVYPSVGMKKQPPVHLA
ANFGQHPFMFDIDGMVKKEKFAIHSEIRATSTANLQPPLDESALLQELVAQFLAHDGYVE
TARAFAEEVAAESAAL-QNGRAEPLKKYEVEEDVEAI-NRQKIRAAILDG-DIDKALKYT
NAY------YANVLQN--FPHIHFKLRCRKFL-------------EMMR------RC---
------------------------------------------------------------
-----------------------------NEPS-WAASRRDKPSN--------GLSDGSA
VFDEEMELDEHMHHGGGW------------------------------NADGMDTEEPEN
A-------------------AKFNELLTEAVQYGQQ---------L-----RL------D
YPNDERGGNKKMLDDIFSLVAYPD--------PMQSVHGHYLDPAGRIAVAEELNSAILV
SLGKSSSAALERLYQQTEVLVNEISEEG-GA-GAFINVRNDFLL-------
>gi|118086379|ref|XP_418927.2|	Gallus gallus
---------------------------------------------------MKQQCVGKK
IRYRTPRRPGSPEPHGPLRAAPLRSPPESDTHRPRASP-------------------PTQ
PQRLAPPPAREGGG---GGGA-PGLAAGSGGGAPAAFP----------------------
-----HGDPALNEQEKELK----------------RRLKRLYPAVDEQETPLP--RSW--
SPKDKFSYIGLSQNNLRVHYKG-HGKTP-KDAA-SVRATHPIPAACGIYYFEVKIVSKGR
DG----------YMGIGLSAQ--GVNMNRLPGWDKHSYGYHGDDGHSF--CSSGTGQPYG
PTFTTGDVIGCCVNLINNTCFYTKNGHSLGIAFT----DLPP-NLYPTVGL-QTPGEVVD
ANFGQHPFVFDIEDYMREWRTKIQAQIDRFPIGDREGEWQ--TMIQKMVSSYLVHHGYCA
TAEAFARSTDQT-----------------VLEELASIKNRQRIQKLVLAG-RMGEAIETT
QQL------YPSLLER--NPNLLFALKVRQFI-------------EMVNGTDSEVRCLGG
HSPKSQDSYPVSPRSFSSPSMSPSHGMNIHNLATGKGSSTHFSGFES-SCSNGVISNKGH
QSYCH-------------S-KHTATSLNVPELN-NINVSRSQQVN------------SYS
SNDVDMET-DHYSNGVAE-------TSSNGFLNGSS------------KHDHEMEECDTE
M---EVDSSQ----LRRQLCGGSQAAIERMIHFGRE---------LQAMSEQL------R
RECGKNTANKKMLKDAFSLLAYSD--------PWSSPVGNQLDPIQREPVCSVLNSAILE
THNLPKQPPLALAMGQASQCLGLMARSGIGS-CAFATVE-DYLH-------
>gi|109128957|ref|XP_001089228.	Macaca mulatta
MATRPQKPPRYQNWGRGMNRGNGERSRLRGRSRFAGGNCSFRILYQPELLRLSRALHCGV
WSSKCGKGVSVSKERCRTRTRFPCGPRRLTGHWLSVADLVPHL--------------PAP
SDTIAAPSKMAAATADPGAGN-PQAGDSSGGGAGGGLP----------------------
-----------SPGEQELS----------------RRLQRLYPAVNQQETPLP--RSW--
SPKDKYNYIGLSQGNLRVHYKG-HGKNH-KDAA-SVRATHPIPAACGIYYFEVKIVSKGR
DG----------YMGIGLSAQ--GVNMNRLPGWDKHSYGYHGDDGHSF--CSSGTGQPYG
PTFTTGDVIGCCVNLINGTCFYTKNGHSLGIAFT----DLPA-NLYPTVGL-QTPGEIVD
ANFGQQPFLFDIEDYMREWRAKVQGTVHCFPISARLGEWQ--AVLQNMVSSYLVHHGYCA
TATAFARMTETP-----------------IQEEQASIKNRQKIQKLVLEG-RVGEAIETT
QRF------YPGLLEH--NPNLLFMLKCRQFV-------------EMVNGTDSEVRSLSS
RSPKSQDSYPGSP------SLSPRHGPS--------SSHMHNTGADSPSCSNGVVSTKSK
QNHSKYPAPSSSSSSSSSSSSSSPSSINYSESN-STDSTKSQPHS-------STSNQETS
DSEMEMEA-EHYPNGVLG-------SMSTRIVNGAY------------KHEDLQTDES--
----SMDDGH----PRRQLCGGNQAATERIILFGRE---------LQALSEQL------G
REYGNNLAHTEMLQDAFSLLAYSD--------PWSCPVGQQLDPIQREPVCAALNSAILE
SQNLPKQPPLMLALGQASECLRLMARAGLGS-CSFARVD-DYLH-------
>gi|74004091|ref|XP_535893.2|	Canis familiaris
--------------------------------------------------MERNLRGVQL
LRLGSGGGADAIRSRNLLVRREKHGQP-EKLECLSVGQCTRAA--------------LPS
SDVFRLELEGEGCTKPLCKAD-VIKGAFQGGDFGSKQNARIHSTEFTRVEIDFCPLKGRM
VQTKPSGEDKLGMRGW-LQ----------------RRLRCLYPAVDEQETPLP--RSW--
SPKDKFSYIGLSQNNLRVHYKG-HGKTP-KDAA-SVRATHPIPAACGIYYFEVKIVSKGR
DG----------YMGIGLSAQ--GVNMNRLPGWDKHSYGYHGDDGHSF--CSSGTGQPYG
PTFTTGDVIGCCVNLINNTCFYTKNGHSLGIAFT----DLPP-NLYPTVGL-QTPGEVVD
ANFGQHPFVFDIEDYMREWRTKIQAQIDRFPIGDREGEWQ--TMIQKMVSSYLVHHGYCA
TAEAFARSTDQT-----------------VLEELASIKNRQRIQKLVLAG-RMGEAIETT
QQL------YPSLLER--NPNLLFTLKVRQFI-------------EMVNGTDSEVRCLGG
RSPKSQDSYPVSPRPFSSPSMSPSHGMNIHNLASGKGSTAHFSGFES--CSNGVISNKAH
QSYCH-------------S-KHQSSNLNVPELN-SINMSRSQQVN------------NFT
SNDVDMET-EHYSNGVGE-------TSSNGFLNGSS------------KHDHEMEDCDTE
M---EVDSSQ----LRRQLCGGSQAAIERMIHFGRE---------LQAMSEQL------R
RECGKNTANKKMLKDAFSLLAYSD--------PWNSPVGNQLDPIQREPVCSALNSAILE
THNLPKQPPLALAMGQATQCLGLMARSGIGS-CAFATVE-DYLH-------
>gi|24668515|ref|NP_524212.2|	Drosophila melanogaster
------------------------------------------------------------
-----------MTAFEEFGVLPELGMATDELDWT--------------------------
---LPTDVQAEAIPLILGGGD-VLMAAETGSGKTGAFC----------------------
--------LPILQIVWETL----------------RDLEEGKAGKGGAIGGAV--TPWTM
SFFDRGNALAVTPDGLRC-----QSREF-KEWH-GCRATTGVRGK-GKFYFEATVTDEG-
------------LCRVGWSTQ--QANLD--LGTCRMGFGFGGTGKKSN--NRQFD--DYG
EAFGKADVIGCLLDLKNQEVSFTKNGQNLGVAFRLPD-NLAKETFYPAVVL---KNAEMQ
FNFGKTDFKYAPGNGFVGACQAGPEHSKANPITGPAAGAP--SAKPAPNAPQAI---IME
PSRELAEQTYNQ-----------------IEKFKYHLSNPEVRSLLLIGGVRLEEQKAQL
MQGTHIVVGTPGRLEEMINSGLVLLTHCRFFVLDEADALLKQGYTELIDRLHKQIPKITS
DGRRLQMVVCSATLHAFEVKKMAERLMHFPTWVDLKGEDAVPETVHHVVCLVDPQMDTTW
QSLRQ---PIGTDGVHDRDNVHPGNHSKETLSQ-AVKLLKGEYCVHAIDKHNMDRAIIFC
RTKQDCDNLERFLRQRGG------KHYSCVCLHGDRKPQERKENLEMFKRQQVKFLICTD
VAARGLDITGLPFMINVTLPDDKTNYVHRIGRVGRAERMGLAISLVATVPEKVWYHGEWC
KSRGRSCNNTNLTEVRGCCIWYNEPNLLAEVEDHLNITIQQVDKTMDVPVNDFDGKVVYG
QKNLRTGSGYEDHVEQLVPTVRKLTELELQSQSLFLKRL-KV---------
>gi|149699690|ref|XP_001496629.	Equus caballus
------------------------------------------------------------
----MWRGIAVSKERCRTRTRFPCGPRWLTGHWLSGADLVPLL--------------PAP
SDTIAAPSKMAAATADPGAGN-PQAGDSSGGGAGSGLP----------------------
-----------SPGEQELN----------------RRLQRLYPAVNQQETPLP--RSW--
SPKDKYNYIGLSQGNLRVHYKG-HGKNH-KDAA-SVRATHPIPAACGIYYFEVKIVSKGR
DG----------YMGIGLSAQ--GVNMNRLPGWDKHSYGYHGDDGHSF--CSSGTGQPYG
PTFTTGDVIGCCVNLINGTCFYTKNGHSLGIAFT----DLPA-NLYPTVGL-QTPGEIVD
ANFGQQPFLFDIEDYMREWRAKVQGTVHCFPISARLGEWQ--AVLQNMVSSYLVHHGYCA
TATAFARMTETP-----------------IQEEQASIKNRQKIQKLVLEG-RVGEAIETT
QRF------YPGLLEH--NPNLLFMLKCRQFV-------------EMVNGTDSEVRSLSS
RSPKSQDSYPGSP------NLSPRHGPS--------SSHMHNTGADSPSCSNGIASTKNK
QNHSKYPAPSSSSSSSSSSSSSSPSSVNYSESN-STDSTKSQPHS-------STSNQETS
DSEMEMEA-EHYPNGVLE-------SMSTRIVNGAY------------KHEDLQTDES--
----SMDDGH----PRRQLCGGNQAATERIILFGRE---------LQALSEQL------G
REYGKNLAHTEMLQDAFSLLAYSD--------PWSCPVGQQLDPIQREPVCAALNSAILE
SQNLPKQPPLMLALGQASECLRLMARAGLGS-CSFARVD-DYLH-------
>gi|149264098|ref|XP_001473804.	Mus musculus
------------------------------------------------------------
-----------MSVSSNKNGRHLCGKEGMTFANSRRRSRARLLSPGR----------AAA
SRRLRGTARRDATRPPVGAARIPQPPEARGRTRARVLA-------------------RAG
EPQAAEKASALNEQEKELQ----------------RRLKRLYPAVDEQETPLP--RSW--
SPKDKFSYIGLSQNNLRVHYKG-HGKTP-KDAA-SVRATHPIPAACGIYYFEVKIVSKGR
DG----------YMGIGLSAQ--GVNMNRLPGWDKHSYGYHGDDGHSF--CSSGTGQPYG
PTFTTGDVIGCCVNLINNTCFYTKNGHSLGIAFT----DLPP-NLYPTVGL-QTPGEVVD
ANFGQHPFVFDIEDYMREWRTKIQAQIDRFPIGDREGEWQ--TMIQKMVSSYLVHHGYCA
TAEAFARSTDQT-----------------VLEELASIKNRQRIQKLVLAG-RMGEAIETT
QQL------YPSLLER--NPNLLFTLKVRQFI-------------EMVNGTDSEVRCLGG
RSPKSQDSYPVSPRPFSSPSMSPSHGMSIHSLAPGKSSTAHFSGFES--CSNGVISNKAH
QSYCH-------------S-KHQLSSLTVPELN-SLNVSRSQQVN------------NFT
SNDVDMET-DHYSNGVGE-------TSSNGFLNGSS------------KHDHEMEDCDTE
M---EVDCSQ----LRRQLCGGSQAAIERMIHFGRE---------LQAMSEQL------R
RECGKNTANKKMLKDAFSLLAYSD--------PWNSPVGNQLDPIQREPVCSALNSAILE
THNLPKQPPLALAMGQATQCLGLMARSGVGS-CAFATVE-DYLH-------
>gi|115908428|ref|XP_784362.2|	Strongylocentrotus purpuratus
------------------------------------------------------------
------------------------------------------------------------
-------------------------MATNGEGTSSAIN----------------------
----------QNTENTDPT----------------DRLKRLYPVVNEDETPLP--RTW--
NPRTKSTFIGLSQNNLRLHYKG-MGKTH-KDAA-SVTTAHSIPASCGIYYFEVTVVSKGR
EG----------YMGIGLSTEEFGNNMSKLPGWDKHSYGYHGDNGHTF--NSAGNGQPYG
PTFTTGDVVGCGVNLVDNTCFYTKNGVHLGIAFT----DLPG-NLYPTVGL-QTPGEIVD
TNFGQSPFVFNIEDLMQEMRMKTKMTIKNYPVPNDQGEWQ--SVLHRIVSTYLVHHGYSQ
TAESFARSTGQT-----------------IAEDVMSIKNRQKLQRLVLAG-CMGEAIATT
QRL------YPSLLQQ--NPNLEFMLKCRQFV-------------EIVSGTESEIRPPRS
EPRSSRSSRSSSRH--ASPAMSPHRDTT--------APSSSSSSSAHLSISSPLATDPLQ
MHHSGIPAYNSSNNNNNSSNNNSNSSNNSSNNN-NNNSKKDYPQT--LVMNGSSSRIINQ
ELDIDMDVDSHETNGVHTNGN---SSNGHAVTNGKA------------LSSSVNGVCPPA
EDMETDDLEGTSLPPVRQLCGGSYSAIEHMLKFGRE---------LQCFYDKI------T
RDNGKNETNANALREAFSLLAYAD--------PWNSEKGYQLDPLLREPVCAALNSAILE
SQNMPKHPPLELALCHVKETIKLMSKYGAGFWGPVLPQE------------
>gi|146324604|ref|XP_746721.2|	Aspergillus fumigatus
---------------MTDAPLPPSGGARRA-PPLSTSYSGPSISSVPRRSSYASVLSGTA
-LSPPSNS-SPPSHPLISNSTTSYPPPYYPDGRLLRPSSSALDADMQLNSPWR----TTP
GDSLPPYSRKFANLPRYDTLF-QNPGSFS--DPSLFTPSYLRNSRYIARLEAARRTKLAS
QRDVPPSASTSNPLSASSSHASLPRIAPSHRGMTYDIIEREPPSDDDHLPPLP--SRW--
SDNDKYSGIELTNGGLEIRYPGPANKHD-HEAA-AVRADHPMPPQCGIYYFEITILSKPK
EGQVFRVDLTRRMIGIGFSSS--KASVERLPGWEQESWAYHGDDGKSFFGENQGQGRPYG
PTFGANDTVGCGVNFVTGCAFFTKNGVFLGNAFR----ELSNLKVYPSVGMKKQPPVHLV
ANFGQQPFMFDIDGMVKREKFSIHSEIYATSTANLQPPLDENALLQELVAQFLTHEGYVD
TARAFSEEVAAESAAL-ENGRKESLTKYEAGEGLDAI-NRQKIRAAILEG-DIDKALKYT
NAY------YGNVLES--YPHIQFKLRCRKFL-------------EMMR------RC---
------------------------------------------------------------
-----------------------------NELS-SAASKKGKASN--------GLSDGSA
VFDQEMELDEQLQEGDGW------------------------------DTEGMDTEESEN
S-------------------GKFHELLTEAVQYGQQ---------L-----RM------D
YPNDERGGDKKVLDDIFSLVAYQD--------PKRSVHGHYLDPAGRVAIAEELNSAILV
SLGKPSSAALERLYQQTEVLVNEISEEG-GA-GAFINVRNDFLL-------
>gi|47228164|emb|CAF97793.1|	Tetraodon nigroviridis
------------------------------------------------------------
-MSGQSSGSGFLMSAVVHGDSVLNEQEKELNQRLRRLYPAVN---------------ENE
TPLPRSWSPKDKFSYIGLSQN-NLRVHYKGHGKTPKDAASVRATHPIPAACGVYYFEVKI
ISKGRDGYMGIGLSAQGVN------------------MNRLP--VNENETPLP--RSW--
SPKDKFSYIGLSQNNLRVHYKG-HGKTP-KDAA-SVRATHPIPAACGVYYFEVKIISKGR
DG----------YMGIGLSAQ--GVNMNRLPGWDKHSYGYHGDDGHSF--CSSGTGQPYG
PTFTTGDVIGCCVNLINNTCFYTKNGHSLGIAFT----DLPP-NLYPTVGL-QTPGEVVD
ANFGQHPFVFDIEDYMREWRTKIQAQIDHFPIGEREGEWQ--SMIQKMVASYLVHHSYCA
TAEAFAKSTDQA-----------------VQEELASIKNRQKIQKLVLSG-RMGEAIDTT
QQL------YPSLLER--NPDLLFMLKVRQFI-------------EMVNGTDSEVRCLGG
RSPKSQDSYPGSPRPFGSPSHKPA------------SSQLYLSGFDSNCCNGVTSKSHSS
SPHSH-------------KPCPPGPASNPPASDISLNGSRSQQNI---------SRCFLR
STDVDMEV-DHFSNGVAE-------SSSNGFLNGSS------------KHAGEADDCEAD
M---EVESAQ----NKRQLCGGSQAAIERMIHFGRE---------LQSMSEHL------R
RECGKNSANKKMLKDAFSLLAYSD--------PWSSPVGYQLDAIQREPVCSTLNSAILE
THNLPKQPPLAQAVGQAAQCLALMARTGSGS-CAFASVD-DYLH-------
>gi|121709181|ref|XP_001272333.	Aspergillus clavatus
---------------MTDAPFPPSGGARGAPPPLPTSYSGPSISSIPRRSSYASVLSGTA
ALSPASNSTSPPAHLLISNSTSSYPPPSHPDGRLLRHSSAADA-DMQLNSSWRTATTTAP
GDSLPLYSRKFANLPRYDTIF-QSPGSFS--DSSSFTPSYLRNSRYIARLDAARRAKLAS
HRDVSSSASASNPLSTSSSHTSLPRIAPSHRGMTYDIIEREPSSDDDRLMPLP--SRW--
SPTDKYAGLELTNGGLEVRYSGPVNKHD-HEAA-AVRADHPMPPQCGIYYFEITILSKPK
EG----------MIGIGFSSN--KASVERLPGWEQESWAYHGDDGKSFFGESQGQGRPYG
PTFGANDTVGCGVNFSTGCAFFTKNGNFLGNAFR----ELRNLKVYPSVGMKKQPPVHLV
VNFGQQPFMFEIDGMVKREKFSIHSEIYATSTANLQPPLDENALFQELVAQFLAHEGYVD
TARAFAEEVAAESAAL-DNGRKDSLKKYEVEEGLDAI-NRQKIRAAILEG-DIDKALKYT
TAY------YGNVLES--HPHIQFKLRCRKFL-------------EMIR------RC---
------------------------------------------------------------
-----------------------------NELS-TASSKKGKATN--------GLSDGSA
VFDQEMELDEQLHEGDGW------------------------------DAEGMDTEEPES
L-------------------GKFHELLTEAVQYGQQ---------L-----RM------D
YPNDERGGDKKVLDDIFSLVAYQD--------PKRSVHGHYLDPAGRLAIAEELNSTILV
SLGKPSSAALERLYQQTEVLVNEIGEDG-GA-GAFINVRNDFLL-------
>gi|114663170|ref|XP_523396.2|	Pan troglodytes
------------------------------------------------------------
------------------------------------------------------------
---------MAAATADPGAGN-PQPGDSSGGGAGGGLP----------------------
-----------SPGEQELS----------------RRLQRLYPAVNQQETPLP--RSW--
SPKDKYNYIGLSQGNLRVHYKG-HGKNH-KDAA-SVRATHPIPAACGIYYFEVKIVSKGR
DG----------YMGIGLSAQ--GVNMNRLPGWDKHSYGYHGDDGHSF--CSSGTGQPYG
PTFTTGDVIGCCVNLINGTCFYTKNGHSLGIAFT----DLPA-NLYPTVGL-QTPGEIVD
ANFGQQPFLFDIEDYMREWRAKVQGTVHCFPISARLGEWQ--AVLQNMVSSYLVHHGYCA
TATAFARMTETP-----------------IQEEQASIKNRQKIQKLVLEG-RVGEAIETT
QRF------YPGLLEH--NPNLLFMLKCRQFV-------------EMVNGTDSEVRSLSS
RSPKSQDSYPGSP------SLSPRHGPS--------SSHMHNTGADSPSCSNGVASTKSK
QNHSKYPAPSSSSSSSSSSSSSSPSSVNYSESN-STDSTKSQHHS-------STSNQETS
DSEMEMEA-EHYPNGVLG-------SMSTRIVNGAY------------KHEDLQTDES--
----SMDDGH----PRRQLCGGNQAATERIILFGRE---------LQALSEQL------G
REYGKNLAHTEMLQDAFSLLAYSD--------PWSCPVGQQLDPIQREPVCAALNSAILE
SQNLPKQPPLMLALGQASECLRLMARAGLGS-CSFARVD-DYLH-------
>gi|113205900|ref|NP_001037977.	Xenopus tropicalis
------------------------------------------------------------
------------------------------------------------------------
-----------------MSSP-PLHGLSSG------------------------------
-----------------------------------GHLSRDPP---------P--RSW--
SPRDKCSYLGLSHGNLRVHYKG-HGKTS-KDAA-SVRSTHPIPAACGIFYFEVKIISKGR
DG----------YMGIGLSTQ--GVNLSRLPGWDKHSYGYHGDDGHSF--CSSGTGQPYG
PTFTTGDVIGCCVNLIDNTCFYTKNGHSLGIAFT----DLPP-NLYPTVGL-QTPGEVVD
ANFGQSPFVFDIEDYIREWRTKIQAQIERFPVG---GEWQ--SMIQRMVSSYLVHHGYCS
TAEAFAKSTDQT-----------------VQEELASIKNRQRIQKLVLSG-RMGEAIETT
QQL------YPSLLER--NPNLLFTLKVRQFI-------------EMVNGTDSEVRCLGN
RSLKSLDGC---------------------------------SGSDS-NCSNGIISNKAH
QTHCH-------------S-KSQSSNLNVTELN-SINMTMSHQLN------------SYS
SNDVEMET-DHYSNGFSA-------STSNGFLNGSS------------RHEPELEECDTE
M---EVDTSH----GRRQLCGGSQAAVERMICFGRE---------LQAMSEQL------R
RERGKNATNKNMLKDAFSLLAYSD--------PWNSPVGYQLDPIQREHVCSSLNSAILD
IHNLPKQPPLSLALEQASQCLEMMAQCGIGS-CAFARVA-DYLH-------
>gi|125977718|ref|XP_001352892.	Drosophila pseudoobscura
------------------------------------------------------------
----------------EFGVLPELGKATDEADWT--------------------------
---LPTDVQAEAIPLILGGGD-VLMAAETGSGKTGAFC----------------------
--------LPILQIVWETL----------------RDLEEGKGGKGGGGTAAAV-TPWTM
SFFDRGNALAVTPDGLRC-----QSREF-KEWH-GCRATTGVRGK-GKFYFETTVTDEG-
------------LCRVGWSTQ--QANLD--LGTCRHGFGFGGTGKKSN--NRQFD--DYG
EAFGKADVIGCLLDLQRLEMSFTKNGQSLGVAFRVPE-NLSKETFYPAVVL---KNAEML
FNFGKTDFKYSPGNGFVGVCQAGPEHSKTNPLSSPTTNAA--AAKPAPNAPQAI---IIE
PSRELAEQTYNQ-----------------IEKFKYHLRNPEVRSLLLIGGVRLDEQKAQL
QQGIHIVVGTPGRLEELINSGYVLLTHCRFFVLDEADALLKQGYTDLIDRLHKQIPKITA
EGRRLQMIVCSATLHAFEVKKMAERLMHFPTWVDLKGEDAVPETVHHVVCLVDPQADRSW
QSLRQ---AIRTDGVHDRDNVHASNPSQETHSQ-AVKLLKGEYCFHAIEKHQMDRAIIFC
RTKQDCDNLEQYLKQRGG------QRFSCVCLHGDRKPQERKQNLEMFKQQKVKFLICTD
VAARGLDITGLPFMINVTLPDDKANYVHRIGRVGRAERMGLAISLVSTVPEKVWYHGEWC
KSRGRNCSNTNLTDVRGCCTWYNEPNLLAEVEDHLNITIQQVDKAMEVPVNDFDGKVVYG
QKNLNTGTGYKDHVEQLVPTVRKLTDLELQSQSLFLKRL-KV---------
>gi|6682820|dbj|BAA88895.1|	Xenopus laevis
------------------------------------------------------------
------------------------------------------------------------
-----------------MSSP-PLHGLSSV------------------------------
-----------------------------------GHLSRDPP---------P--RSW--
SPRDKCSYLGLSHGNLRVHYKG-HGKTS-KDAA-SVRSTHPIPAACGIFYFEVKIISKGR
DG----------YMGIGLSTQ--GVNLNRLPGWDKHSYGYHGDDGHSF--CSSGTGQPYG
PTFTTGDVIGCCVNLIDNTCFYTKNGHSLGIAFT----DLPP-NLYPTVGL-QTPGEVVD
ANFGQSPFVFDIEDYIREWRSKIQAQIERFPVA---GEWQ--SMIQRMVSSYLVHHGYCS
TAEAFAKSTDQT-----------------VQEELASIKNRQRIQKLVLSG-RMGEAIETT
QQL------YPSLLER--NPNLLFTLKVRQFI-------------EMVNGTDSEVRCLGN
RSLKSPDGC---------------------------------LGSDS-NCSNGIISNKAH
QTHCH-------------S-KSQSSNLNVTELN-SINMTMSHQLN------------SYS
SNDVEMET-DHYSNGFSA-------STSNGFLNGSS------------RHEPELEECDTE
M---EVDTSH----GRRQLCGGSQAAVERMICFGRE---------LQAMSEQL------R
RERGKNATNKNMLKDAFSLLAYSD--------PWNSPVGYQLDPIQREHVCSSLNSAILD
IHNLPKQPPLSLALEQASQCLEMMAQCGIGS-CAFARVA-DYLH-------
>gi|156550743|ref|XP_001606114.	Nasonia vitripennis
------------------------------------------------------------
-----------MAAFEEMGVLPEISKALEEMEWM--------------------------
---LPTDVQAEAIPLILGGGD-VLMAAETGSGKTGAFC----------------------
--------IPILQIVWETL----------------KDIESGKATAKVGEAVHS--PTWLL
SLYDRGHALAVTPDGLRC-----QSREI-KEWH-GCRATKGIQGN-GKYYYEAIVTDEG-
------------LCRVGWSTQ--QASLD--LGTDKFGWGYGGTGKKSN--SKQFD--NYG
EAFGMNDVIGCLLDLGKGEIKFWKNGADLGPAFFLNQQQKSQ-TFFPAVVL---KNAEMS
FNFGAQPFKYPPPQGYIAVCEAPKEQVKINPVNSSQSQAAKVDLKPPNNAPQAI---VIE
PSRELAEQTFTQ-----------------IQKFKKYIKDPEIRELLVVGGESIKDQITVL
NHGVNIVVGTPGRLESLIQDGCLLLSQCRFFVLDEADGLLKQNYGEMIERLHRQMPKITN
DGKRLQMIVCSATLHAFEVKKMAEKLMHFPTWVDLKGEDAVPETVHHVVVMVDPQKDTLW
QNLRR---HIQTDGVHSRD-NLRATNTAEALSE-AIKKLKGEYCLRAIKEHKMDRALIFC
RTKLDCDNLERYLKQVGD------RELTCVCLHGDRKPHERKQNLEKFKREEARFLICTD
VAARGLDIKGLPFMINMTLPDEKSNYVHRIGRVGRAERMGLAISLVSSVPEKVWYHGEWC
SSRGRNCNNTNLTEQGGCCIWYNEQRLLAEIEDHLNITIQQIENDIKVPIHDFDGKVTYG
EKRVGTGSNYEDHVQEMAPVVAELAALESQAQLIYLRRH-QTVR-------
>gi|91083553|ref|XP_966900.1|	Tribolium castaneum
------------------------------------------------------------
------------------------------------------------------------
-------------MAAVSNGR-SAMDSQSETQNVVV------------------------
-----------------------------------DRLKRLYPAVNEEKSPLP--RAW--
SPKEKYNYIGLSQNNLRVHYKG-HGKTH-RDAA-SVQATHPIPAACGLYYFEVKIVSKGR
DG----------YMGIGLSAQ--GVNMNRLPGWDKQSYGYHGDDGHSF--CSSGTGQPYG
PTFTTGDVIGCGVNLIDNTCFYTKNGHHLGTAFT----DLPP-NLYPTVGL-QTPGEVVD
ANFGQEPFVFDIEDMMRELGTRTRMEINDFPVPESHGEWQ--AILNKMVSTYLVHHGYCN
TAEAFAHITEQP-----------------FNEDIVSIKNRQKILKLVLAG-RMGEAIERT
SRL------YPGLLES--NQNLLFMLKCRQFV-------------EMVNGSDVEV---CH
RKSGYSPSYSVSPRP------------------------------SSPIQTSVIQSTKSY
SNKSK-------------QSVEEMNQNNTTPTH-NGNSCREVPVI------------LAD
DGDVEMDTTEEFRNGHGDACNGKSNSSTNGYQNGNSHSNNVT------QDDGCCDNEDED
M---EVDVP-----VCRKSC--SKPAVERILEFGRE---------LYSMSQRL------T
VDKNSSETNQKMLEDAFSLLAYSN--------PWASPVGWQLQPSQRESVCASLNSAILE
SNKKPRKPPLEVAIAHAHELVKLMSTAGLGS-CAFASLV-DILDQ------
>gi|157014552|gb|EAA13221.5|	Anopheles gambiae
------------------------------------------------------------
-----------MTAFEEFGVMPEIAKAIDEMEWM--------------------------
---LPTDVQAEAIPLILGGGD-VLMAAETGSGKTGAFC----------------------
--------LPILQIVWETL----------------RDIKEGKTCKTSSHKGQP----WTF
SYTDRGQAMAITPDGLRC-----QSREF-KEWH-GSRCTTGVRGK-GKYYYEATVTDEG-
------------LCRVGWSTE--LASLD--LGTDRFGYGFGGTGKKSN--CKQFD--AYG
EAFGKQDVIGCMLDLDGREIAFSKNGTSLGTAFKLSEADAKNNSYFPAVVL---KNAEIA
FNFGQTDFKYPLPAGYAAVCNVAKENLTENPNTGPSGSAEGEAAKPKPNAPQAI---VIE
PSRELAEQTFNQ-----------------IRKFKKHLKDPEVRELLLIGGVNVREQIEVL
QRGVDIIVATPGRLEDLIGGGYVLLNSCRFFVLDEADGLLKQGYTEMIDRLHKQIPKITS
DGRRLQMVVCSATLHSFEVKKMAERLMHFPTWVDLKGEDAVPETVHHVVCMVDPQKDISW
QSMRT---HIQTDGVHARDNVRPGSNTAETLSE-AVKMLKGEYTLKAIDEHNMDRAIIFC
RTKLDCDNMERYLRQVGG------QKYSCVCLHGDRNPKERKANLEKFKNKEVKFLICTD
VAARGLDITGLPFIINVTLPDEKSNYVHRIGRVGRADRMGLAFSLVASVPEKVWYHGQWC
SSRGKNCWNTELTDVKGCCMWYDEKMYLAEIEDHLTVTIPQIEKDMKVPLNEFDGKVVYG
EKRMNTGTGYKDHVEQLGPVVRELARLEREAQTLYLKRL-AV---------
>gi|149638666|ref|XP_001515014.	Ornithorhynchus anatinus
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-----------------------HGKTP-KDAA-SVRATHPIPAACGIYYFEVKIVSKGR
DG----------YMGIGLSAQ--GVNMNRLPGWDKHSYGYHGDDGHSF--CSSGTGQPYG
PTFTTGDVIGCCVNLINNTCFYTKNGHSLGIAFT----DLPP-NLYPTVGL-QTPGEVVD
ANFGQHPFVFDIEDYMREWRTKIQAQIDRFPTGDREGEWQ--TMIQKMVSSYLVHHGYCA
TAEAFARSTDQA-----------------VLEELASIKNRQRIQKLVLAG-RMGEAIETT
QQL------YPSLLER--NPNLLFTLKVRQFI-------------EMVNGTDSEVRCLGG
RSPKSQDSYPVSPRSFSSPSMSPSHGMNIHCLASSKGNTTHFPGFES-CCSNGVISNKAH
QTYCH-------------S-KHQSTSLNVPELN-SINVSRSQQVN------------SFT
SNDVDMET-DHYANGVGE-------SSSNGFLNGSS------------KHDHEMEECDTE
M---EVDSSQ----LRRQLCGGSQAAIERMIHFGRE---------LQAMSEQL------R
RECGKNTANKKMLKDAFSLLAYSD--------PWSSPVGNQLDPIQREPVCSALNSAILE
THNLPKQPPLALAMGQATQCLGLMARSGIGS-CAFATVE-DYLH-------
>gi|39812378|ref|NP_005484.2|	Homo sapiens
------------------------------------MSGQPPPPPPQQQQQQQQLSPPPP
AALAPVSGVVLPAPPAVSAGSSPAGSPGGGAGGEGLGAAAAALLLHPPPPPPPATAAPPP
PPPPPPPPASAAAPASGPPAP-PGLAAGPGPAGGAPTPALVAGS--------------SA
AAPFPHGDSALNEQEKELQ----------------RRLKRLYPAVDEQETPLP--RSW--
SPKDKFSYIGLSQNNLRVHYKG-HGKTP-KDAA-SVRATHPIPAACGIYYFEVKIVSKGR
DG----------YMGIGLSAQ--GVNMNRLPGWDKHSYGYHGDDGHSF--CSSGTGQPYG
PTFTTGDVIGCCVNLINNTCFYTKNGHSLGIAFT----DLPP-NLYPTVGL-QTPGEVVD
ANFGQHPFVFDIEDYMREWRTKIQAQIDRFPIGDREGEWQ--TMIQKMVSSYLVHHGYCA
TAEAFARSTDQT-----------------VLEELASIKNRQRIQKLVLAG-RMGEAIETT
QQL------YPSLLER--NPNLLFTLKVRQFI-------------EMVNGTDSEVRCLGG
RSPKSQDSYPVSPRPFSSPSMSPSHGMNIHNLASGKGSTAHFSGFES--CSNGVISNKAH
QSYCH-------------SNKHQSSNLNVPELN-SINMSRSQQVN------------NFT
SNDVDMET-DHYSNGVGE-------TSSNGFLNGSS------------KHDHEMEDCDTE
M---EVDSSQ----LRRQLCGGSQAAIERMIHFGRE---------LQAMSEQL------R
RDCGKNTANKKMLKDAFSLLAYSD--------PWNSPVGNQLDPIQREPVCSALNSAILE
THNLPKQPPLALAMGQATQCLGLMARSGIGS-CAFATVE-DYLH-------
>gi|157017008|gb|EAA09482.5|	Anopheles gambiae
------------------------------------------------------------
-----MADNAPAAAASSVKCSSDGGQPRDSL--------------------------LMS
SSRMFNPNNNVQQQGASGSGN-SGTTPGGGVGGAGGAA----------------------
------AAAGPNAAAAGPI----------------DRLRMLYPNVNEAVDPLP--RSW--
SLQDKCSTIGLTQNNLRVHYKG-IGKSH-TDAA-SVRTAYPIPAACGLYYFEVKIISKGR
DG----------YMGIGLTHT--NFKMNRLPGWDKQSYGYHGDDGHSF--CSSGNGQPYG
PTFTTGDIIGCGVNLVDNTCFYTKNGHHLGIAFR----DLPP-RLYPTVGL-QTPGEVVD
ANFGQEPFKFDIEDMLKELRASTKATIYNFPLPDDQGDWT--VILHKMVSSYLVHHGYSS
TAETFARSAGQT-----------------LQEDMTSIKNRQKIIKLVLSG-RMGQAIEQT
IRL------YPGLLES--NQNLLFMLKCRQFI-------------EMVNGSDFDLGTPSS
RTSPVQTSV--------------------------------------------IQSTKSY
QNGNT---------IIPDNADNQGYLKNNVLSN-NTNNNNGSCIE------------DDY
SNDVEMEN-GHSNN-----------SATNGYKNGSAANRTNTNELVEEEEEEADTGRDED
M---DVDSSLSP--NCKSTSATAKSGVERMLEFGRE---------LFQMSQRL------E
KEHGVNETNQKMLEDAFSLLAYSN--------PWASPLGWQLCPSRREAVCAALNSAILE
SMNYSWRPPLEVCIAHACELLRLMSSSSLGA-CAFVSVD-DILAQQQQH--
