>gi|109485753|ref|XP_236919.4|	Rattus norvegicus
------------------------------------------------------------
-----------------------------------------------------MDRCKHV
GRLRLAQDHSILNPQKWCCLECATT-----------------------------------
----ESAWACLKCSHVACG---RYIEDHALKHFEETGHPLAME--VRDLYVF--------
----------------------------CYLCKDYVLND---NPEGDLKLLRSSLLAVRG
QKQDLPARRGRTLRSTAAGEDVVPPQRTPQGQPQMLTALWYRRQRLLAKTLRLWFEKS--
----------SRGRAQLEQRRQEEALERKKEAARQRRREVKRRLLEELASAPPRKSARLL
LHAPGPVA----VRPATLATSRRMSAAALKPRRQLAVAPGVTGLRNLGNTCYMNSILQVL
SHLQKFRECFLNLDPSTSEHLFPQATNGKAQIPSRPASSTAAGFSVRSDRAQGFEPQGFC
WSSGASISRSLELIQNKEPSSKHISLCHELHTLFRVM----WSGKW----ALVSPFA---
-MLHSVWSLI--PAFRGYDQQDAQEFLCELLHKVQQELES--------------------
------------------------------------------------------------
-----------------------------------------EGSTRRILIPFSQRKLT--
---------------KQVLK----------------------------------------
--------------------VVN----------TIFHGQLLSQVTCVSCNYK-SNT-IEP
FWDLSLEFPERYHCVEKG--FV-PLNQTECLLTEMLAKFTETEALEGRIYA-CDQCNSKR
RKSNPKPLV--------------------------------------------------L
SEA------------RKQLMIYRLPQVLRLH-----------------------------
---------------------------------------------LKRFRWSGR-NHREK
IGVHVVFD-QVLTMEPYCCGDMLSSLDKD-------------------------------
-----------------------------------TFAYDLSAVVMHHGKGFGSGHYTAY
CYNT--------------------EGGFWVHCNDSKLDVCSVEEVCKTQA-YILFYT-RR
TVQGSAKLSEPHLRAQVHSSSKDDRRTYTFP-----------------------------
---------------------------
>gi|3800762|gb|AAC68864.1|	Gallus gallus
------------------------------------------------------------
------------------------------------------------------------
----MGGHYTAYCKSP---------ISSEWHSF---------------------------
--------------------------NDSRVTPMSSGH-------------V--------
----------------------------STSTL----------------LSRRRAVSHSD
LAQEF--SGLHTSDS-AYAPSP---------------------------------SAL--
----------YQAATRSDYVRDYLE----KSSHCSLPSSPSSSQLCER------------
--DDGYGG----TH--------GPDPTSSK------VVQGLTGLGNLGNTCFMNSILQCL
SNTKELRDYCLQN-----------------------------------------------
----------QYLRDLNNNSRMRTALMSEFAKLIQLL----WTSSPN---HSVSPSE---
-FKTQIQRYA--PRFVGYNQQDAQEFLRFLLDGLHGEVNR--------------------
------------------------------------------------------------
------------------------------------------VLVRPRANADTLDHLP--
---------------DDEKS-----------------------------RQMW----RRY
QER--------------EDSRVS----------DLFVAQLKSSLTCSECGYC-STA-FDP
FWDLSLPIP------KKG--YG-EVTLMDCL-----RLFTKEDVLDGDEKPTCCRCKA--
-----------------------------------------------------------R
TRC------------TKKFSIQKFPKILVLH-----------------------------
---------------------------------------------LKRFSEAR--IRASK
LTTFVNFPLKDLDLREFASQSCNHA-----------------------------------
-------------------------------------VYNLYAVSNHSGATMG-GHYTAY
CKSP--------------------ISSEWHSFNDSRVTPMSSSHVPTSDA-YLLFYD---
LASPSSRM----------------------------------------------------
---------------------------
>gi|140832741|gb|AAI35926.1|	Xenopus tropicalis
------------------------------------------------------------
------------------------------------------------------------
MSWAPVSTWSRRTPLAACCSAPELPPAGAW------------------------------
-------KACAAGSLRIGP---QGRCKMMKNWGMIGGIAAALA--AGIYVLW--------
----------------------------GPIS-DRKKYR---------------------
-------KGL--------------------------------------------------
------------------------------------------------------------
----------------------------------------VPGLLNLGNTCFMNSLLQGL
ASCPSFIRWLADF-----------------------------------------------
----------TSKYRQENNTTEHQHLSVTLLHLLKAL----CNQEGTED-EVLDASP---
-LLEVLRAHR--WQISSFEEQDAHELFHVLTSSLEDERDR--------------------
------------------------------------------------------------
--------------------------------------------RPHVTHLFDLDSLE--
---------------FPLEP----------------------------QRQIH----CRT
QVPIYPIP---------SQWKSQ----------HPFHGRLTSNMVCKHCQHQ-SPMRYDT
FDSLSLSIP------VAT--WGHPITLDQCL-----QHFISTESVKDVV---CENCTKIH
AAQIPNSQSVENR----------------------------------------------K
TTF------------VKQLKLGKLPQCLCIH-----------------------------
---------------------------------------------LQRLSWSNQ-GSPLK
RNEHVQFS-EFLAMDRFKYRISGCSTSKQ--PANHLSAAEQETTDGKEGGAQNPTMPFLN
GA------CSTS----YISPPFTSPLPTNPEWTSSSYLFRLMAVVVHHGDMHS-GHFVTY
RRSP-------------AAKNQKLTSQQWLWISDDTVRRTNFQEVLSSSA-YLLFYE---
RIQSNLHHPEDQRAAEK-------------------------------------------
---------------------------
>gi|21361712|ref|NP_004196.3|	Homo sapiens
------------------------------------------------------------
------------------------------------------MSQLSSTLKRYTESARYT
DAHYAKSGYGAYTPSSYGANLAASLLEKEKLGFKPVPTSSFL-TRPRTYGPSSLLDY---
----DRGRPLLRPDITGGG---KRAESQTRGTERPLGSGLSGG--SGFPYGV--------
----------------------------TNNCLSYLPIN---AYDQGVTLTQK-LDSQSD
LARDF--SSLRTSDSYRIDPRNLGRSPMLARTRKELCTL----------------QGL--
----------YQTASCPEYLVDYLENYGRKGSASQVPSQAPPSRVPEIISPTYRPIGRYT
LWETGKGQ----APGPSRSSSPGRDGMNSK------SAQGLAGLRNLGNTCFMNSILQCL
SNTRELRDYCLQR-----------------------------------------------
----------LYMRDLHHGSNAHTALVEEFAKLIQTI----WTSSPN---DVVSPSE---
-FKTQIQRYA--PRFVGYNQQDAQEFLRFLLDGLHNEVNR--------------------
------------------------------------------------------------
------------------------------------------VTLRPKSNPENLDHLP--
---------------DDEKG-----------------------------RQMW----RKY
LER--------------EDSRIG----------DLFVGQLKGSLTCTDCGYC-STV-FDP
FWDLSLPIA------KRG--YP-EVTLMDCM-----RLFTKEDVLDGDEKPTCCRCRG--
-----------------------------------------------------------R
KRC------------IKKFSIQRFPKILVLR-----------------------------
---------------------------------------------LKRFSESR--IRTSK
LTTFVNFPLRDLDLREFASENTNHA-----------------------------------
-------------------------------------VYNLYAVSNHSGTTMG-GHYTAY
CRSP--------------------GTGEWHTFNDSSVTPMSSSQVRTSDA-YLLFYE---
LASPPSRM----------------------------------------------------
---------------------------
>gi|109108985|ref|XP_001105333.	Macaca mulatta
------------------------------------------------------------
------------------------------------------MSQLSSTLKRYTESARYT
DAHYSKSGYGAYTPSSYGANLAASLLEKEKFGFKPVPASSFL-TRPRTYGPSSILDY---
----DRGRPLLRPNITGGG---KRAESQTRGTERPSGSGLSGG--SGFPYGV--------
----------------------------SNNCLSYLPMN---AYDQGVTLTQK-SDSQSD
LARDF--SSLRTSDNYRIDPGNLGRSPMLARTRKELCTL----------------QGL--
----------YQAASRPEYLVDYLENYGRKGSASQVPSQTPPSRVPEILSPTFRPIGRYT
LWEKGKGQ----APGPSRSSSPGRDSMNSK------SAQGLAGLRNLGNTCFMNSILQCL
SNTRELRDYCLQR-----------------------------------------------
----------LYMRDLHHSSNAHTALMEEFAKLIQTI----WTSSPN---DVVSPSE---
-FKTQIQRYA--PRFVGYNQQDAQEFLRFLLDGLHNEVNR--------------------
------------------------------------------------------------
------------------------------------------VTLRPKSNPENLDHLP--
---------------DDEKG-----------------------------RQMW----RKY
LER--------------EDSRIG----------DLFVGQLKSSLTCTDCGYC-STV-FDP
FWDLSLPIA------KRG--YP-EVTLMDCM-----RLFTKEDVLDGDEKPTCCRCRG--
-----------------------------------------------------------R
KRC------------IKKFSIQRFPKILVLH-----------------------------
---------------------------------------------LKRFSESR--IRTSK
LTTFVNFPLRDLDLREFASENTNHA-----------------------------------
-------------------------------------VYNLYAVSNHSGTTMG-GHYTAY
CRSP--------------------GTGEWHTFNDSSVTPMSSSQVRTSDA-YLLFYE---
LASPPSRM----------------------------------------------------
---------------------------
>gi|16198231|gb|AAL13936.1|	Drosophila melanogaster
------------------------------------------------------------
---------------------------------MRACVCVCVQCEIETRKASEKSQKFTK
KKPNYFQNWAARRRTAKVAKIRRKQRKCDKAFVPLQSSAKRAKTKENSVDSNTSVFSSSS
SSSSGRSFGRGTERWAVGA---EAGRGTAENETLAVAAAAATTTNAGRFITADLIKTVNS
DKQRDRVAKGHRDAKNPLDATKHLRLSDCLRTVQKLAIE-LESADAGSDASAQANASADA
SSAVMSETGCRHYQSYVKEHSYDTFRVIDAYFAACVNRDARERKAIHCNCFECGSYGIQL
YACLHCIYFGCRGAHITSHLRSKKHNVALELSHGTLYCYACRDFIYDARSREYALINRKL
EAKDLQKSIGWVPWVPTTKETNLLLANARRRLVRPNQTIGLRGLLNLGATCFMNCIVQAL
VHTPLLSDYFMSD-----------------------------------------------
-------------RHDCGSKSSHKCLVCEVSRLFQEF----YSGSR----SPLSLHR---
-LLHLIWNHA--KHLAGYEQQDAHEFFIATLDVLHRHCVK--------------------
------------------------------------------------------------
----------------------------------------------AKAEHESKSNSS--
---------------GSGSG-------------------------TNSSNSSS----SHC
YGQ--------------CNCIID----------QIFTGMLQSDVVCQACNGV-STT-YDP
FWDISLDLGETT---THG--GVTPKTLIDCL-----ERYTRAEHLGSAAKIKCSTCKS--
-----------------------------------------------------------Y
QES------------TKQFSLRTLPSVVSFH-----------------------------
---------------------------------------------LKRFEHSA--LIDRK
ISSFIQFP-VEFDMTPFMSEKKNAY-----------------------------------
----------------------------------GDFRFSLYAVVNHVGTIDT-GHYTAY
VRHQ---------------------KDTWVKCDDHVITMASLKQVLDSEG-YLLFYH---
--KNVLEYE---------------------------------------------------
---------------------------
>gi|115722937|ref|XP_781718.2|	Strongylocentrotus purpuratus
------------------------------------------------------------
------------------------------------------------MECPHLSQNVKQ
EVCQIIKKSHGESTSSWVCAVCRSN-----------------------------------
----KNPWMCLACGVVLCG---RYVNGHAKKHYEENQHSASIN--CENLAVY--------
----------------------------CYVCDDHALND---NKTETIKHVRQFLQAKVN
LQYE---KQLKTLTGDVAGDHIDG------------------------------------
---------------------------------------PPRKKLAAN------------
------------------------------------TRANIPGLRNLGNTCFMNAVLQSL
SNINQFCGYFKDL----------------------------PAVELRSGKTAG-------
----------KRIYNTRNMKHDDVSLVEEIRKTLCAL----WQGDQ----TAISPDS---
-LFTVMWKIF--PRFRGYQQQDAHEFMRYLLDRLHTELQG--------------------
------------------------------------------------------------
---------------------------------------------------STWPTTP--
---------------KKQTN----------------------------------------
----------------GHATIVS----------VIFGGLLLSEVTCRPCGSL-YKK-IDP
FLDVSLDIPERFRPRSKNKDGSQVCRLQDCM-----QSFIAVEELEETEQYMCPKCQQ--
-----------------------------------------------------------R
QPS------------TKKFWLKAIPNVLCIH-----------------------------
---------------------------------------------LKRFTWSG--FLRTK
IDTYVQFPMKGLDIQPFMLGPENVSTT---------------------------------
-------------------------------------VYDLAAVIVHQGSGAGAGHYIAF
AVNN----------------------GQWYCFNDSTVTPVEEKVITRCKA-YILFYVSHQ
FKDDFLSFSSIHNGNIPS------------------------------------------
---------------------------
>gi|149634278|ref|XP_001508127.	Ornithorhynchus anatinus
------------------------------------------------------------
------------------------------------------------------------
-MLSPRGLRRLLRTGA--------------------------------------------
----------------------AVRYKVMKNWGVLGGIAAALV--AGIYVLW--------
----------------------------GPIT-ERKKRR---------------------
-------KGL--------------------------------------------------
------------------------------------------------------------
----------------------------------------VPGLLNLGNTCFMNSLLQGL
SACPAFIKWLEDF-----------------------------------------------
---------TAQYSTDQKETSTDRYLSLTLLRLLKAL----SCQDVMND-DVLDASC---
-LLEVLRLYR--WQISSFEEQDAHELFHVITSSLEDERDR--------------------
------------------------------------------------------------
--------------------------------------------QPRVTHLFDIQSLE--
---------------QQPEI---------------------------IPQQVT----CRT
RGTPHPLP---------SHWNSQ----------HPFHGRLTSNMVCKHCERQ-SPVRYDT
FDSLSLSIP------AAT--WGRPVTLDHCL-----HHFISSESVRDVV---CDNCTKIE
AEGTLNGEMVENQ----------------------------------------------R
TTF------------VKQLKLGKLPQCLCIH-----------------------------
---------------------------------------------LQRLSWSNH-GTPLK
RHEHVQFN-EFLIMDIYKYHLPGHKASQHNPKKKDPALEMKTAAAIKRAAVDQPGGPKTL
VM-------NGACSPALLPSPITLSLPVIPDYSSSSYLFRLMAVVVHHGDMHS-GHFVTY
RRSPP------------PAKSPRSASSQWLWISDDTVRKASLQEVLSSSA-YLLFYE---
RVLSKTEPRGQEYKSEE-------------------------------------------
---------------------------
>gi|125815963|ref|XP_687498.2|	Danio rerio
------------------------------------------------------------
----------------------------------MLQMKDVWDGFFCIVFIMHGIEAELS
SISTIKSAAIMISAQLQMATGPKAKHQQHRNNI---SMRGRFCQRARLNANTAVKVRVSL
LSSTGVPAVCAVCPTFKNTCIALFRNKMMKNWGVIGGIAAAMA--AGVYVLW--------
----------------------------GPIS-DRRKKR---------------------
-------KGM--------------------------------------------------
------------------------------------------------------------
----------------------------------------VPGLLNLGNTCFMNSLLQGL
AACPSFIRWLEDF-----------------------------------------------
---------TSQNSADRERTERETQLSRSLMQLLKAL----SSHDPGED-DVLDAGG---
-LLEALRLYR--WHISSFEEQDAHELFHVLTSSLEEEQER--------------------
------------------------------------------------------------
--------------------------------------------QPRVAHLFDMQTLE--
---------------KSVES---------------------------KEKNIS----CRS
GGPLHPIP---------SLWRTR----------HPFHGRLTSYMACKRCEQQ-SPVHYDS
FDSLSLSIP------SIQ--WGRPVTLDQCL-----QHFISSETIKEVE---CENCTKQQ
AGELVNGEVLESQ----------------------------------------------R
TTF------------VKQLKLGKLPQCLCIH-----------------------------
---------------------------------------------LQRLTWSKE-GSPIK
RQEHVQFT-EYLSLDRYKHCSAAQSQQKTSRTNKAKASADPKDKAIANGVDSEHCNNNKP
QS------NGTFPSVFLHSPGLSSQLNLTYDYSTSEYLFRLTAVLVHHGDMHS-GHFITY
RRCPA------------APRGTSPFSSQWLWVSDDSVRKASLQEVLSSSA-YLLFYE---
RMQRPGLRVEE-------------------------------------------------
---------------------------
>gi|74006273|ref|XP_536136.2|	Canis familiaris
MALQDQHSPPSRDLLIPLCSAGCCSTGLRAGRTLQLLPGKALCCKPGGQATAGCRWPGGT
NKPFGGPCGGTDLGIGCCHGCSPALGGAARGEQGVALSWGSAPAGLPRRLTGGQVQPVVS
TMPQASEHRLGRTREP---PVNVQPRVGSKLPFAPRARSKE--RRNPAPGPNPMLRP---
----LPPRPGPPEERLKKL---ELGRGRTSG-PRPRGP-LRAD--HGVPLPG--------
----------------------------SPPPTVALPLP---SRTN---LARSKSVSSGD
L------RPMGIALGGHRGAGELG-------------------------------AAL--
----------SRLALRPE-----PPTLRRSASLRRLGGFPGPPTLLSIRTEPPTSHGSFH
VISARPSE----SF----YSDDKMAHHTLL------LGSGHVGLRNLGNTCFLNAVLQCL
SSTRPLRDFCLRR-----------------------------------------------
-----------DFRQEVPGGGRAQELTEAFADVIGAL----WHPDSC---EAVNPTR---
-FRAVFQKYV--PSFSGYSQQDAQEFLKLLMERLHLEINRRGRRAPPILASSPA------
------------------------------------------------------------
-----------------------------------------PAQPRRGGALLEEPELS--
---------------DDDRA-----------------------------NLMW----KRY
LER--------------EDSKIV----------DLFVGQLKSCLKCQACGYR-STT-FEV
FCDLSLPIP------KKGFAGG-KVSLRDCF-----SLFTKEEELESENAPVCDRCRQ--
-----------------------------------------------------------K
TRS------------TKKLTVQRFPRILGLD-----------------------------
---------------------------------------------LNRFSASR--GSIKK
SSVGVDFPLQRLSLGDFASDKAGSP-----------------------------------
-------------------------------------VYQLYALCNHSGSVHY-GHYTAL
CRCQ---------------------TG-WHVYNDSRVSPVSENQVASSEG-YVLFYQ---
LMQEPPRCL---------------------------------------------------
---------------------------
>gi|70997075|ref|XP_753292.1|	Aspergillus fumigatus
------------------------------------------------------------
------------------------------------------------------------
-MNARRGGFDILTQSPFHNPQNSQH-----------------------------------
----------------------ETFLQRLQSNNNTLTYGVAIG--LLVYFVL--------
----------------------------NYFGVAPILIS-RALWNLIVYLTPSRIVVALD
SKTSNLDSTDKALLSMNFQTKSEAMQRIL-------------------------------
-----------------------------GLNNSSLSSFLPCSTTFSGFGTALLGAKNHL
----------------------------------------PPGLGNWDNSCYQNSIIQGL
ASLLSLAEFLEHN-----------------------------------------------
--------------IRTLGDKGSFSTHQALRGVIERL----NNADN--------------
-HDQRLWIPAELKSMSSWQQQDAQEYFSKVVGQVDHEVQQATKRRTRNLG----------
------------------------------------------------------------
-----------------------------------------LKMAGPVENIIGAEPHT--
---------------DVDGA-------------------------DSSSPRLA----ERH
LTR------------------------------NPLEGLLAQRVGCMKCGWT-EGLSLIP
FNCLTVPLG--------G--QY-EYDVRQCL-----DQYMHLEPIEGVE---CAKCTLLR
AKDQLENLLNQIEEDMKLPNTPDSSKVSGALRTSAEERLRAVEEALEEDDFAEKT---LS
KKCHIPSKNRVTSTKSRQAVIARTPKCLVIH-----------------------------
---------------------------------------------INRSMFDENTGMLRK
NYAAVRFP-NVLDLNEWCLGTKSSSWGQM-------------------------------
-----------DIERWGTDPRESMLPEAGSASDVPGRFFELRAVVTHYGRHEN-GHYICY
RKYPSDVFPAHVPDTVLEADGEKDKAERWFRLSDDDVQMVSEASVMSQGGAFMLFYE---
AIDRQGSDYTPTHGTHAVEDEKLESVCDLTTSNDMSTTSTITDGSPDTSPATSVSAADRF
DVPLYKLQLLTDDHASSLGESSLEVTP
>gi|66549197|ref|XP_392918.2|	Apis mellifera
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
--------------------------MDVEKVAVFASIGFAIA--IAIFVLW--------
----------------------------GPSPKPRKKGK---------------------
------------------------------------------------------------
------------------------------------------------------------
----------------------------------------VIGINNLGYTCFLNSLLQAL
AACPIFIGWL--------------------------------------------------
--------------KKQYDKNGKVNFISTLLSVFEKI----NGYAE----DLYGDVT---
-PIEIISSLGNQWKFAP-GHQDVHELFHIVLNALQAEIQS-GSRKGCLSDALPQSPIM--
------------------------------------------------------------
-----------------------------------------ITDTKKLGDPLTFRSVSCN
DIVSVNKNPNIPNGFDKNCNNHVISSTTSISSIPMAYNK--PGIILARSSELL----SRN
VKLEGNK-ESFKPWSSLCAMSFSNT--TISVEVHPFSGSLTSQLQCSCCKWK-SAVHYDK
LETISLPLPPLG---TYI--KS-YHTVEELL-----TRFVTSEIVQDVL---CDGCGM--
-----------------------------------------------------------R
CLA------------TKTLTLGKLPKCLCLH-----------------------------
---------------------------------------------ISRTTWSSS-GIPIK
RDDPVKFP-EILTLDPYTFTETKKRNAQG-------------------------------
--------------------DPEATMLLSRTTIQDKHKYQLRAIVEHRGPVDS-GHFVCY
RRGN--------------------KMNQWLYTSDNVVEI----NLEICDD----------
------------------------------------------------------------
---------------------------
>gi|149720502|ref|XP_001496995.	Equus caballus
------------------------------------------------------------
---------------------------------------------------------MAL
TWWWWKTSSGGFSTGVLDSSRAASSLRRQLLGG-GSRQGPAHETKPPPPG----------
----DRGETPVAKEKKDNKDVVRRLLLSGSGSFRSPGEPVLRPTFPEELGVW--------
----------------------------LRVPPPREPAE---AWVRP-------------
-------RGCGGFRGRDAELRA--------------------------------------
--------------------------------ERVTARQAHPALPADRGGRQYKVMKNWG
VIGGIAAALAAGIYVIWGPITERKKRRKGL----------VPGLVNLGNTCFMNSLLQGL
SACPAFIRWLEEF-----------------------------------------------
---------TSQYARDQMEPPPHQYLSLTLLHLLKAL----SCQEVTDD-EVLDASC---
-LLDVLRMYR--WQISSFEEQDAHELFHVITSSLEDERDR--------------------
------------------------------------------------------------
--------------------------------------------QPRVTHLFDVHSLE--
---------------QQSEA---------------------------TPKQIT----CRT
RGSLHPTF---------THWKSQ----------HPFHGRLTSNMVCKHCEHQ-SPVRFDT
FDSLSLSIP------AAT--WGHPLTLDHCL-----HHFISSESVRDVV---CDNCTKIE
AKGTLNGEKVEHQ----------------------------------------------R
TTF------------VKQLKLGKLPQCLCIH-----------------------------
---------------------------------------------LQRLSWSSH-GTPLK
RHEHVQFN-EFLMMDIYKYHLLGHKPGQRGPKLKENPGPVVELQDGPAAPRSVLNQPGGP
KTQIFMNGACSPSLLPTLPTPMPFPLPVVPDYSSSSYLFRLMAVVVHHGDMHS-GHFVTY
RRSPP------------SAKNPLSTSSQWLWISDDSVRKASLQEVLSSSA-YLLFYE---
RVLSRTQQQSPEYKSEE-------------------------------------------
---------------------------
>gi|114052120|ref|NP_001039841.	Bos taurus
------------------------------------------------------------
------------------------------------------------------------
-MPQASEHRLGRTREP---PLNIQPRVGSKLPFAPRARSKE--RRNPAPGPNPMLRP---
----LPPRPGPPEERLKKL---ELGRGRTSG-PRPSGP-LRAD--HGVPLPG--------
----------------------------SPPPTVALPLP---SRTN---LARSKSVSSGD
L------RPMGIALGGHRGTGELG-------------------------------AAL--
----------SRLALRPE-----PPPLRRSTSLRRLGGFPGPPTLFSIRTEPPTPHGSFH
VISARPSE----PF----YSDDKMAHHTLL------LGSGHVGLRNLGNTCFLNALLQCL
SSTRPLRDFCLRR-----------------------------------------------
-----------DFRQEVPGGGRAQELTEAFADVIGAL----WHPDSC---EAVNPTR---
-FRAVFQKYV--PSFSGYSQQDAQEFLKLLMERLHLEINRRGRRAPPILASSPA------
------------------------------------------------------------
-----------------------------------------PHPPRLGGALLEEPELS--
---------------DDDRA-----------------------------NLMW----KRY
LER--------------EDSKIV----------DLFVGQLKSCLKCQACGYR-STT-FEV
FCDLSLPIP------KKGFAGG-KVSLRDCF-----NLFTKEEELESENAPVCDRCRQ--
-----------------------------------------------------------K
TRS------------TKKLTVQRFPRILVLH-----------------------------
---------------------------------------------LNRFSASR--GSIKK
SSVGVDFPLQRLSLGDFASDKAGSP-----------------------------------
-------------------------------------VYQLYALCNHSGSVHY-GHYTAL
CRCQ---------------------TG-WHVYNDSRVSPVSENQVASSEG-YVLFYQ---
LMQEPPRCL---------------------------------------------------
---------------------------
>gi|6323879|ref|NP_013950.1|	Saccharomyces cerevisiae
------------------------------------------------------------
----------------------------------------------------------MS
ICPHIQQVFQNEKSKDGVLKTCNAARYILNHSV------------PKEKFLNTMKCGTCH
EINSGATFMCLQCGFCGCW-----NHSHFLSHSKQIGHIFGIN--SNNGLLF--------
----------------------------CFKCEDYIGNI---------------DLINDA
ILAKYWDDVCTKTMVPSMERRD--------------------------------------
------------------------------------------------------------
---------------------------------------GLSGLINMGSTCFMSSILQCL
IHNPYFIRHSMSQ-----------------------------------------------
-----------IHSNNCKVRSPDKCFSCALDKIVHELYGALNTKQASSSSTSTNRQTGFI
YLLTCAWKIN--QNLAGYSQQDAHEFWQFIINQIHQ------------------------
------------------------------------------------------------
------------------------------------------------SYVLDLPNAK--
---------------EVSRA---------------------------NNKQ---------
-----------------CECIVH----------TVFEGSLESSIVCPGCQNN-SKTTIDP
FLDLSLDIKD-------------KKKLYECL-----DSFHKKEQLKDFNYH-CGECNS--
-----------------------------------------------------------T
QDA------------IKQLGIHKLPSVLVLQ-----------------------------
---------------------------------------------LKRFEHLLN-GSNRK
LDDFIEFP-TYLNMKNYCSTKEKDKHSEN-------------------------------
-------------------------------GKVPDIIYELIGIVSHKGTVNE-GHYIAF
CKIS---------------------GGQWFKFNDSMVSSISQEEVLKEQA-YLLFYT---
IRQVN-------------------------------------------------------
---------------------------
>gi|91092390|ref|XP_968702.1|	Tribolium castaneum
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
--------------------------MESDRILVAAGLTAAAV--VGAFVFW--------
----------------------------GPATTSGSG-----------------------
-------RGR--------------------------------------------------
------------------------------------------------------------
----------------------------------------LAGLVNLGKTCFLNAVLHAL
AACPQFIEWLEKD-----------------------------------------------
------------------RCVKETSLRRTLATVLSVV----NGTNKSVK-ETYAPAA---
-VINALKRLG--WVIPA-GEQDAHELLNVLLTTLDEETHKITRKAGCLSDALGMNELDVT
EPEEE-------------------------------------------------------
-----------------------------------------TSEFNTLGSVMSLNELC--
---------------RPSSL---------------------NWRGTAIRRNRWISRSCRA
LQMSGP-----------PQQPVS----------HPFTGTLTSQLRCTECGHK-SSVRYDK
FESLSLALPSGAG--DLG--WG-RHKLHQLL-----TNFVTPEVVPDVQ---CEGCNSGR
DPAMPAI----------------------------------------------------L
SKQ------------IKILNFGKLPVCLCIH-----------------------------
---------------------------------------------ISRNTWQP--GGISK
RQDYVQFP-MRLSLAAYTFVHAHYQRKLT--------------------------NSVYT
ST------SEGGSPLSSSMPMSWGVGSLSEMANEFRNVYQLAAVVVHTGDAHS-GHFITY
RRGH-------------HNTNYVLINYRWYYTSDVEIREVMVDEVLQSTA-YMLFYE---
RTSNLSGF----------------------------------------------------
---------------------------
>gi|157018877|gb|EAA06470.4|	Anopheles gambiae
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
--------------------------MESEKLLMAAGVTAAVV--VGAFVFW--------
----------------------------GPSGSSKLRQR---------------------
-------RGQ--------------------------------------------------
------------------------------------------------------------
----------------------------------------IAGLHNFGKTCFLNTLLQAL
AACPQFIAWL--------------------------------------------------
---------------QLHNTKDKKSLVSSLQNVLEVV----NGTHPTLRGDPYAPGA---
-VIRALHALG--WVISP-EEHDAHELLLVMLSSLEEEVSK-PRKIGCLSDALDDVVGGGG
GGG---------------------GDLGFHAI---PARPSSAMLSDFCNAEYDESTSLMR
YTRSEAHTPDSPHSVCTENEEQSQESSLVEFGASPSHAISVAFGGRRFGSRMQLQQQQ--
---------------QQTMV--RPTPMGRDEQTSVGMGDAGGNHFAGKRHSAS----YRS
LERLNRGPGRVSVWGDRQQAQIP----------HPFRGGMGSQLCCGGCGHK-STVRYDK
FDSITLPLP------ETA--AP-GLGIGNLL-----SDFIQPETLDAVQ---CDACHE--
-----------------------------------------------------------T
TAH------------TKTLTFSKLPACLCIH-----------------------------
---------------------------------------------IARTTWHAS-GHVHK
RLDSVHFP-ETLSMAPYSFVQPGLNSNIS-TPWG-------STTSLYSAGLMASGLDAVG
GG------AQAGPGAADAPSGSMTFGSYTFGAMFPRNLYRLLAVIVHSGEANA-GHFVTY
RRGA------------------LRNSYKWYYTSDTIVREVPIEEVLNSSA-YMLFYD---
RGSSSKYP----------------------------------------------------
---------------------------
>gi|38259220|ref|NP_940813.1|	Mus musculus
------------------------------------------------------------
-----------------------------------------------------MDRCKHV
GRLRLAQDHSILNPQKWCCLQCATT-----------------------------------
----ESAWACLKCSHVACG---RYIEDHALKHFEETGHPLAME--VRDLYVF--------
----------------------------CYLCKDYVLND---NPEGDLKLLRSSLLAVRG
QKQDLLARRGRTLRSTAAGEDVVPPQRTPQGQPQMLTALWYRRQRLLAKTLRLWFQKS--
----------SRGRAQLEQRRQEEALERKKEAARQRRREVKRRLLEELASAPPRKSARLL
LHAPGPVA----VRPATLATSRRLSAAALNPRRQPAVAPGVTGLRNLGNTCYMNSILQVL
SHLQKFRECFLNLDPSTSEHLFPQATNGKAQLSGRPASSSAAELSVRSVRAQGCEPQGLC
WSSGASISRSLELIQNKEPSSKHISLCHELHTLFRVM----WSGKW----ALVSPFA---
-MLHSVWSLI--PAFRGYDQQDAQEFLCELLHKVQQELES--------------------
------------------------------------------------------------
-----------------------------------------EGSTRRILIPFSQRKLT--
---------------KQVLK----------------------------------------
--------------------VVN----------TIFHGQLLSQVTCISCNYK-SNT-IEP
FWDLSLEFPERYHCIEKG--FV-PLNQTECLLTEMLAKFTETEALEGRIYA-CDQCNSKR
RKSNPKPLV--------------------------------------------------L
SEA------------RKQLMIYRLPQVLRLH-----------------------------
---------------------------------------------LKRFRWSGR-NHREK
IGVHVIFD-QVLTMEPYCCRDMLSSLDKE-------------------------------
-----------------------------------TFAYDLSAVVMHHGKGFGSGHYTAY
CYNT--------------------EGGFWVHCNDSKLDVCSVEEVCKTQA-YILFYT-RR
TVQGSAKLSEPHLQAQVHSSSKDERRTYTLP-----------------------------
---------------------------
>gi|156544454|ref|XP_001607643.	Nasonia vitripennis
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
--------------------------MDVDKISVFTAVGFALA--VGAFVLW--------
----------------------------GP---SPRPRR---------------------
-------KGQ--------------------------------------------------
------------------------------------------------------------
----------------------------------------VVGIKNLGYTCFLNSLLQSL
AACPAFIEWL--------------------------------------------------
--------------RRRQEDVKGESFTSSLMLVIDKI----NGFTD----DMFGSVR---
-PVEVITSLGPLWNFAP-GHQDAHELFHVFLSALQAELQTACRK-GCLSDALPKAPLV--
------------------------------------------------------------
-----------------------------------------ITDIKGSGDPVNLRSVSCN
DIASANERCEVPRETNKNLSNHVVTYAQSITNVSASMTSIKPGIILARSSEII----SKI
IGESGDDGDSLRPWSSMCAIPSQNTTPSFSNKVHPFSGLLTSQLICTACEWK-SPVHFDK
LESVSLPLPPV----TDGFMWK-RLTLVDLL-----SRLVSKEVINDVQ---CDGCNN--
-----------------------------------------------------------R
CAA------------YKTLTFGKLPKCLCLH-----------------------------
---------------------------------------------IPRTTWSSS-GKPIK
RDDPVIFN-EALILDPFTYTDTKRKNTQS-------------------------------
-----------------QGSLHSMALLNGQSLQRGKHKYYLYAVIEHRGPVDA-GHFVCY
RRGN--------------------RPGQWLYTSDTIVQKTTLEDVLSASP-YLLFYE---
RAVTRDQQ----------------------------------------------------
---------------------------
>gi|125979911|ref|XP_001353988.	Drosophila pseudoobscura
------------------------------------------------------------
--------------------------------------------AKVAKIRRKQRKSDKA
FVPQPCSKRTKTKENSVDSTTSVISITSSSSST-----HSAAGRCVATEENETVARS---
----GRGRGVERG---------KDDKDEATGSESDGGAKLTKGPLNAAYLSA--------
----------------------------CLRTVQKLAIELDVSVDAKSVASREREASGVM
SE-----TGCRHYQSYLKEHGYDTYRVIDAYFSACVNKDARLKKAIHCYCFECGSASIQL
YACLHCIYFGCRGSHIHSHLRAKKHHVALELSHGTLYCHACRDFIYDSRSREYALINRKL
EAKDLQKSLGWQPWIPSAKDSNLLLANPRRRLVRPNQTIGLRGLLNLGATCFMNCIVQAL
VHTPLLSDYFMSD-----------------------------------------------
--------------RHDCGKSSHKCLVCEVSRLFQEF----YSGSR----SPLSLHR---
-LLHLIWNHA--KHLAGYEQQDAHEFFIATLDVLHRHCVK--------------------
------------------------------------------------------------
----------------------------------------------AKAEHESKSNSS--
---------------SSGSG-------------------------TNSTSSST----SSY
GQ---------------CNCIID----------QIFTGMLQSDVVCQACKGV-STT-FDP
FWDISLDLGETT---THG--GVTPKTLIDCL-----ERYTRAEHLGSAAKIKCSTCKS--
-----------------------------------------------------------Y
QES------------TKQFSLRTLPSVVSFH-----------------------------
---------------------------------------------LKRFEHSA--LIDRK
ISSFIQFP-VEFDMTPFMSEKKNAY-----------------------------------
----------------------------------GDFRFSLYAVVNHVGTIDT-GHYTAY
VRHQ---------------------KDTWVKCDDHVITMASLKQVLDSEG-YLLFYH---
--KNVLEYE---------------------------------------------------
---------------------------
>gi|150864363|ref|XP_001383141.	Pichia stipitis
------------------------------------------------------------
------------------------------------------------------------
----MSSNYKFANRSRF-------------------------------------------
----------------------TTRKSKSHRFAIKNGGEIGGLSNDGNTCFM--------
----------------------------NSVLQSLASSR---------------------
-------ELLKFIDSYLFSETALQTP----------------------------------
-----------------------------QGNVISMKSNSPRPEL---------------
--------------------------------------------------IFTNALKTLL
------------------------------------------------------------
--------------DNLNGKYGARGKEFSTKALLNKM----PNGPKQ-------------
------------NFFSGYNQEDAQEFYQLVMSLLEREYKKVSQSRLPTPEPEEK------
------------------------------------------------------------
-----------------------------------------AGNQEKQVRFLDIENVP--
---------------NVVFG-------------------------CEKLGKLG----KVY
VPANQVDPNLVDCDHKVFPLELI----------TPVDGISAERIGCLSCGEV-GGIRYSV
NSGLSLNLPNN----SSY--YS-SFDLLSLM-----NDWITPEIIEDVN---CNRCGLNQ
TKEFLLETLQDLQAKPNGDKLREQFQIRLDAIDSELLKPHITDEVFEKLTIKKHI---RK
SRK------------SKQILLSRPPPLLSIH-----------------------------
---------------------------------------------INRSVFDPRTYMIVK
NSSSVTFP-SKLNLAPYIAEPRDINMDAR-LPFRKQEERTVLQQEQTKNSETLPSTPSDS
SL------SSTPEETKSDSTTSTDIDNLEPLPVDPKLLYNLKAVISHYGTHNY-GHYICY
RQLR----------------------GTWWRISDESVYVVTEEEVLNAQGTFMIFYE---
FDDGHKEFLQDVSDSEEEEEEEED------------------------------------
---------------------------
>gi|114560771|ref|XP_001173063.	Pan troglodytes
------------------------------------------------------------
------------------------------------------------------------
-MPQASEHRLGRTREP---PVNIQPRVGSKLPFAPRARSKE--RRNPASGPNPMLRP---
----LPPRPGPPDERLKKL---ELGRGRTSG-PRPRGP-LRAD--HGVPLPG--------
----------------------------SPPPTVALPLP---SRTN---LARSKSVSSGD
L------RPMGIALGGHRGTGELG-------------------------------AAL--
----------SRLALRPE-----PPTLRRSTSLRRLGGFPGPPTLFSIRTEPPASHGSFH
MISARSSE----PF----YSDDKMAHHTLL------LGSGHVGLRNLGNTCFLNAVLQCL
SSTRPLRDFCLRR-----------------------------------------------
-----------DFRQEVPGGGRAQELTEAFADVIGAL----WHPDSC---EAVNPTR---
-FRAVFQKYV--PSFSGYSQQDAQEFLKLLMERLHLEINRRGRRAPPILANGPV------
------------------------------------------------------------
-----------------------------------------PSPPRRGGALLEEPELS--
---------------DDDRA-----------------------------NLMW----KRY
LER--------------EDSKIV----------DLFVGQLKSCLKCQACGYR-STT-FEV
FCDLSLPIP------KKGFAGG-KVSLRDCF-----NLFTKEEELESENAPVCDRCRQ--
-----------------------------------------------------------K
TRS------------TKKLTVQRFPRILVLHILIFRFLLLLGYLPYILFPPCFQRIEFSL
GKVCHPLFHKMLPVCREWGEDSFQDRRSSPQRPTASQMLLNQGLDLNRFSASR--GSIKK
SSVGVDFPLQRLSLGDFASDKAGSP-----------------------------------
-------------------------------------VYQLYALCNHSGSVHY-GHYTAL
CRCQ---------------------TG-WHVYNDSRVSPVSENQVASSEG-YVLFYQ---
LMQEPPRCL---------------------------------------------------
---------------------------
>gi|126326536|ref|XP_001370349.	Monodelphis domestica
------------------------------------------------------------
------------------------------------------MSQLSSTLKRYTDSSRYT
DTPYSKSSYGSYTPSSYGTNLAASFLEKEKLNFKPAHSSGFLNTRPRTYGPASILDY---
----DRGRPVLRPEVGGII---KRGESQSRITERPSGSGLSGG--SNLPYGM--------
----------------------------PSSSLNYLPIN---SRDQVVPLTQKKSNSHSD
LARDF--SGLRTTDGYRMDPGP-GRSPMLARTRKELCAL----------------QGL--
----------YQAASRSEYLSDYLENYGRKGSASQGPAPAP--RALEALSPTYRPNGRYS
LWEKGKGS----SP----STSPGRDIMTSK------STQGLAGLRNLGNTCFMNSILQCL
SNTRELRDYCLQR-----------------------------------------------
----------LYLRDLNSSSHAHTALMEEFAKLIQTI----WTSSAN---DVVSPSE---
-FKTQIQRFA--PRFVGYNQQDAQEFLRFLLDGLHNEVNR--------------------
------------------------------------------------------------
------------------------------------------VTVRPKSNPENLDHLP--
---------------DEEKG-----------------------------RQMW----RKY
LER--------------EDSRIG----------DLFVGQLKSSLTCTECGYC-STV-FDP
FWDLSLPIA------KRG--YP-EVTLMDCM-----RLFTKEDVLDGDEKPTCCRCRA--
-----------------------------------------------------------R
KRC------------IKKFSIQKFPKILVLH-----------------------------
---------------------------------------------LKRFSESR--IRTSK
LTTFVNFPLRDLDLREFASENTNHA-----------------------------------
-------------------------------------VYNLYAVSNHSGTTMG-GHYTAY
CRSP--------------------VTGEWHTFNDSSVTPMSSSQVRSSDA-YLLFYE---
LASPPSRM----------------------------------------------------
---------------------------
>gi|121714062|ref|XP_001274642.	Aspergillus clavatus
------------------------------------------------------------
------------------------------------------------------------
-MNARRGGYDILTQSPFYDHRNSQH-----------------------------------
----------------------ETLLERLQNSTL-ITYGLATV--LVIYFIL--------
----------------------------NYTGVAPSSIP-QALWNLVVHLTPSRIVVVLD
SKTTNPDSTDQNLHSMSFQAKSEAMQRIL-------------------------------
-----------------------------GLNHSSFAAFLPRSNTFSGFGTALLGNKDSL
----------------------------------------PPGLGNWDNSCYQNSIIQGL
ASLDSLEEFLGRN-----------------------------------------------
--------------IQDLGEKGPLSTHAALKTIIERL----NSADN--------------
-HSQRLWTPADLKSMSSWQQQDAQEYFAKVVGQIDQEVQQATKRQTNNLG----------
------------------------------------------------------------
-----------------------------------------LKMAGPGEHIVGSGALS--
---------------RTLDD---------------------------VQDSLS----RRN
HPP-------------------R----------NPLEGLLAQRVGCMKCGWT-EGLSLIP
FNCLTLPL-------GVK--Y--EYDLRDCL-----DQYMHLEPIEGVE---CAKCTLLR
AKDQLGNLLKQIEDDAKLQSGTESPNMSNALQTSAQERLRAVEEALEEDDFAEKT---LT
KKCHIPTKSRVTSIKSRQAVIARTPNCLVIH-----------------------------
---------------------------------------------INRSVFDENTGMLRK
NHAAVRFP-NVLDLNEWCLGKKSSACDQK-------------------------------
-----------DTEQWDTDPRESMLPEAGSTASVSGRLFQLQAVVTHYGRHEN-GHYICY
RKYSSKTFPTHVPDTVVEADGEKEKSERWFRLSDDDVQMVSEASVMSQGGVFMLFYE---
MIDRLPSEHTEMEHLYAAEGEETESISSFVASEDMSTTSTITEGSCDTSPATSVSASARA
ETPFEKV--------------------
>gi|108870994|gb|EAT35219.1|	Aedes aegypti
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
--------------------------MEGDRFLMAAGVTAAVV--VGAFVFW--------
----------------------------GPSGNSRLRQR---------------------
-------RGQ--------------------------------------------------
------------------------------------------------------------
----------------------------------------IAGLHNFGKTCFLNTLLQAL
AACPQFIAWL--------------------------------------------------
---------------QLHNTKDKKTLVSSLQNVLEVV----NGTHPTLRGDPYSPGA---
-VIRALNAQG--WVIPP-DEHDTHELLHVLLNSLEEEVTK-PKKIGCLSDALGEEELRA-
--------------------------------MMPPARPSSAMLSDFCNAEYDESTNLTR
YVRSEAHTPDSPHSTCTETE---------------------DSMTGLEGSLMDCAGSP--
---------------PSIISTFSGRPSRPKSILATDMGRNGT---LDKRSSGS----CRS
LERLTRGPGRVSVWGDRKQIQVP----------HPFRGGLSSQLCCSGCGYK-SVVRYDK
FDSVTLSLP------EIK--NP-GISVGSLL-----TEFIQPETLNGVQ---CESCNE--
-----------------------------------------------------------T
TTH------------TKTLTFSKLPACLCIH-----------------------------
---------------------------------------------IARTTWLPT-GHAYK
RQDFVHFP-ETLSMAPYSFVQPSLNSAMS--------------------------TPWGS
TMSLYSATPTEQNTPVGSVGSAFNFGSYTFGAMFPKNLYRLLAVIVHSGEANS-GHFVTY
RRGA------------------LRNSHKWYYTSDTVVKEVTIEEVLSTPA-YMLFYD---
-RGPSSKYTQP-------------------------------------------------
---------------------------
>gi|125983104|ref|XP_001355317.	Drosophila pseudoobscura
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
--------------------------MESEKILMAAGVTVAAV--VGAFVLW--------
----------------------------GPSG-ARLRQR---------------------
-------RGQ--------------------------------------------------
------------------------------------------------------------
----------------------------------------IAGLHNFGRTCFLNTLLQAL
AACPQFIAWLQ-------------------------------------------------
--------------LYNGASPDRKSLISSMLNTLEVI----NGTHATLRGDPHSPGA---
-VLRALNTLG--WVIPQ-EEHDAHELFHVLLSSLEEEAIR-PQPLGCLSDALPGPPGHDD
DSSSSIGIETPAGGGFRPLNSVAVGVGASQRMGDQPNRPSSAMLTDFLNMDYDESTNLTR
LVRSEAHTPDSPASVCEREGNDRIGSLLDAISPGTSLMGQQPFGFPLCSEALPIDSLT--
---------------TPTVG------GGERLSRPRQPQSQEVGEGLNRRVSAS----CRS
LERLHRGPGRVSIWSNMMPSQVA----------HPFQGAMGAQLVCNGCGSK-SSVRYDK
FDSIILNLP------TQR--RT-GLSLGHLL-----SEYITSEDLSDVK---CDSCNE--
-----------------------------------------------------------T
TTH------------TKSVTFAKLPGCLCIH-----------------------------
---------------------------------------------IARTVWLPT-GQVCK
RRDYVHFP-ESLSMAPYSFVQPHLNSQAT-TPWG--------------------------
--------STMSLFSSSLPMNNAVGGVEGFGTMFPKNLYRLLAVVVHTGEANS-GHFVTY
RRGS------------------LRNAHRWFYTSDTIVREVSIDEVLSVPA-YLLFYD---
RGQQRPM-----------------------------------------------------
---------------------------
