>gi|114674781|ref|XP_001140426.	Pan troglodytes
------------------------------------------------------------
------------------------------------------------------------
---MGSEDHGA---QNPS-------------------------CKIMTFRPTMEEFKDFN
KY-VA--YIESQGAH-RAGLAKIIPPKEWKPR----QTYDDID--DVVIPAPIQQVV---
-TGQSGL-----------------------------FTQYNI------------------
--QKKAMTVGE---------YRRL--------------------------ANSEKYCTP-
------------------------------------------------------R-HQDF
------------------------------------------------------DD----
------------------------------------------------------------
-------------LERKYWKNLTFVSP-I---YGADI----SGSL-----YDD-------
------------------------------D-VAQWNIGSLR----TILDMVERECGTII
EGVNTPYLYFGMWKTTFAWHTEDMDLYSINYLHFGEPKSWYAIPPEHGKRLERLAI---G
FFPGSSQGCDAFLRHKMTLISPIILK-KYGIPFSR-------------ITQEAGEFMITF
P--------------------YGYHAGFNHGFNCAESTNFATLRWIDYG---KVATQCTC
RKDMVKISMDVFVRILQPERYELWKQGKDLTVLDHTRPTALTSPELSSWSASRASLKAKL
LRRQISLKENRHWRKTEEERKPSLERKKEQTKRPGLSSHRKRSQPKKPKPEDPKFPGEGT
AGAALLEEAGGSVKEEAGPEVDPEEEEEEPQPLPHGREAEGAEEDGRGKLRPTKAKSERK
KKSFGLLPPQ---LPPPPAHFPSE-----------EALWLPSPLEPPVLGPGPAATEESP
LPAPLN----VVPPEVPSEELEA--KPRPI--IPMLYVVPRPGKAAFNQEHVSCQQAF-E
HFAQKGPTWKEPVSPMELTGPEDGAASSGAGRMETKARAGEGQAPSTFSKLKMEIKKSRR
--HPLGRPPTRSPLSVVKQEASSDEEASPFSGEEDVSD---PDALRPLLSLQWKNRAASF
QAERKFNAAAARTEPYCAICTLFYPYCQALQTEKEAPTASLGEGCS--ATLPSKSRQKTR
PLIPEMCFTSGGE----------NTEPLPAN------------------------SYIGD
DGTS-------------------PLIACGKCCL-----------QVH-------ASCYGI
RPELVNEG--WTCSRCT----AHAWTAECCLCNLRGGAL---QMTTDRRWIHVIC-----
-AI-AVP--------EARFLNVI---ERHPVDISAIPEQRW---------------KLKC
VYCR-KRMKKVSGACIQCSYEHC------STSFHVTCAHAAGVLMEPDDWPYVVSITC-L
KHKSGG---------------------------HAVQLLR----AVSL-----GQVV-IT
K---NRNGLYYRCRVIGAASQTCYEVNFD-DGSYSDNLYPESITSRDCVRLGPPSEGE--
-LVELRWTDGNLYKAKFISSVTSHIYQVEFEDGSQLTVKRGDIFTLEEELP--KRVRSRL
SLST------GAPQEPA--FSGEEAKAAKRPRVG-----TPLA--TE------DSGRSQD
------------------------------------------------------------
----------------------------YVAFVESLLQAQ----GRPGAPF
>gi|149028204|gb|EDL83642.1|	Rattus norvegicus
------------------------------------------------------------
------------------------------------------------------------
---MGSEDHSA---QNPS-------------------------CKIMTFRPTMDEFRDFN
RY-VA--YIESQGAH-RAGLAKIIPPKEWKPR----QTYDDID--DVVIPAPIQQVV---
-TGQSGL-----------------------------FTQYNI------------------
--QKKAMTVGE---------YRRL--------------------------ANSEKYCTP-
------------------------------------------------------R-HQDF
------------------------------------------------------DD----
------------------------------------------------------------
-------------LERKYWKNLTFVSP-I---YGADI----SGSL-----YDD-------
------------------------------D-VAQWNIGNLR----SILDMVERECGTII
EGVNTPYLYFGMWKTTFAWHTEDMDLYSINYLHFGEPKSWYAIPPEHGKRLERLAI---G
FFPGSSQGCDAFLRHKMTLISPIILK-KYGIPFSR-------------ITQEAGEFMITF
P--------------------YGYHAGFNHGFNCAESTNFATLRWIDYG---KVATQCTC
RKDMVKISMDVFVRILQPERYEQWKQGRDLTVLDHTRPTALSSPELSSWSASRTSLKAKL
LRRQISVKESRPWRKAEEERRPSLERRREPTRRPGPASHRRRSQPKKSKPEDSRSPGEAT
AGVAGLDEARGCSRRETMPE----EEEEEELSPSQGHEAEGVEEDGRGKPRPTKARSKKK
TPSLLSPPLL----SAPPALFPAE-----------EVLRLPPQPKSPGPAMGPMAAEGGP
PPTALN----VVPPGVPGEETEV--RPRPI--IPMLYVLPRANSSDGDREHAAHPQ---L
APMELGPEEEDQAQAGDSQGTTSFSK------------------------LKVEIKKSRR
--HPLGRPPTRSPLSVVKQEASSDEEAFPFSGEDDGSD---PEALRSLLSLQWKSKAASF
QAERKLNAAAALSEPYCAVCTLFYPYSQSVQTEREVLATPGDS--A--VQPPSKSGQRTR
PLIPEMCFTSSGE----------NTEPLPAN------------------------SYVGE
DGTS-------------------PLISCAHCCL-----------QVH-------ASCYGV
RPELAKEG--WTCSRCA----AHAWTAECCLCNLRGGAL---QRTTEHRWIHVIC-----
-AI-AVP--------EVRFLNVI---ERNPVDVSAIPEQRW---------------KLKC
VYCR-KRMKRVSGACIQCSYEHC------STSFHVTCAHAAGVLMEPDDWPYVVSITC-L
KHRASG---------------------------AGGQLLR----TVSL-----GQIV-IT
K---NRNGLYYRCRVIGTTAQTFYEVNFD-DGSYSDNLYPESITSRDCLRLGPPPEGE--
-LVELRWTDGNLYRARFISMATSLIYQVEFEDGSQLTVKRADIFTLEEELP--KRVRSRL
SLST------GTPQEPS--FSGDGVKAAKRPRVA-----TVLATTTE------DTGRSPE
------------------------------------------------------------
----------------------------YLAFMESLLQAQ----GQPGAPF
>gi|109123032|ref|XP_001083379.	Macaca mulatta
------------------------------------------------------------
------------------------------------------------------------
---MGSEDHGA---QNPS-------------------------CKIMTFRPTMEEFKDFN
KY-VA--YIESQGAH-RAGLAKIIPPKEWKPR----QTYDDID--DVVIPAPIQQVV---
-TGQSGL-----------------------------FTQYNI------------------
--QKKAMTVGE---------YRRL--------------------------ANSEKYCTP-
------------------------------------------------------R-HQDF
------------------------------------------------------DD----
------------------------------------------------------------
-------------LERKYWKNLTFVSP-I---YGADI----SGSL-----YDD-------
------------------------------D-VAQWNIGSLR----TILDMVERECGTII
EGVNTPYLYFGMWKTTFAWHTEDMDLYSINYLHFGEPKSWYAIPPEHGKRLERLAI---G
FFPGSSQGCDAFLRHKMTLISPIILK-KYGIPFSR-------------ITQEAGEFMITF
P--------------------YGYHAGFNHGFNCAESTNFATLRWIDYG---KVATQCTC
RKDMVKISMDVFVRILQPERYELWKQGKDLTVLDHTRPTALTSPELSSWSASRASLKAKL
LRR----------------------------------SHRKRSQPKKPKPEDPKSPGEGT
AGATLLEEAGGSVKEEAGPEADPEEEEEEPQPLPHGREAEGAEEDGRGKLRPTKAKNERK
KKSFGPLPPQ---LPTPPAHFPSE-----------EALWLPSSLEPAVLGPGPSAMEENP
LPAPLN----VVPPEVPSEELEA--KPRPI--IPMLYVVPRPGKAAFNQEHMSCQQAF-E
HFAQKGPTWKEPASPMELMGPEDGGTSSGAGRVETKVRAGEGQAPSTFSKLKMEIKKSRR
--HPLGRPPTRSPLSVVKQEASSDEEASPFSGEEDVSD---PEALRPLLSLQWKNRAASF
QAERKFNATAARTEPYCAICTLFYPYCQALQTEKEAPTASLGEGSS--ATLPSKSGQKTR
PLIPEMCFTSGGE----------NTEPLPAN------------------------SYIGD
DGTS-------------------PLIACGKCCL-----------QVH-------ASCYGI
RPELVNEG--WTCSRCA----AHAWTAECCLCNLRGGAL---QMTTDRRWIHVIC-----
-AI-AVP--------EARFLNVI---ERHPVDISAIPEQRW---------------KLKC
VYCR-KRMKKVSGACIQCSYEHC------STSFHVTCAHAAGVLMEPDDWPYVVSITC-L
KHKSGG---------------------------HAVQLLR----AVSL-----GQVV-IT
K---NRNGLYYRCRVIGAATQTCYEVNFD-DGSYSDNLYPESITSRDCVRLGPPSEGE--
-LVELRWTDGNLYKAKFISSVTSHIYQVEFEDGSQLTVKRGDIFTLEEELP--KRVRSRL
SLST------GAPQEPA--FSGEEAKAAKRPRVG-----TPLA--TE------DSGRSQD
------------------------------------------------------------
----------------------------YVAFVESLLQAQ----GRPGGPF
>gi|47216587|emb|CAG00622.1|	Tetraodon nigroviridis
------------------------------------------------------------
------------------------------------------------------------
---------GA---KNPS-------------------------CKIMTFRPTVEEFQDFA
RY-IV--YMESQGAH-RAGLAKVIPPEGWKPR----KSYDTIE--DMVIPAPITQVV---
-TGQSGL-----------------------------FTQYNI------------------
--QKKSMTVGE---------YRKL--------------------------ANSKKYCTP-
------------------------------------------------------R-HKDF
------------------------------------------------------DD----
------------------------------------------------------------
-------------LERKYWKNLTFVSP-I---YGADV----SGSI-----YDE-------
------------------------------G-IQEWNIGHLN----TLLDMVEQECGIVI
EGVNTPYLYFGMWKTTFAWHTEDMDLYSINYLHFGQPKSWYSVPPEHGKRLERLAQ---G
FFPGSSQGCDAFLRHKMTLISPSILK-KYGIPFDRASNEYIYCVFSEQVTQNEGEFMITF
P--------------------YGYHAGFNHGFNCAESTNFATLRWVDYG---KMATQCSC
RKDMVKISMDVFVRCLQPDRYELWKQGKDSTVLDHLKPTKLSSPELESWRQRRILYRENL
LRR----------------------------------AMQKIKQFRRLKLEEVKVLAEEG
FELNAAEYQQQVEKREAQRR----QEREERLAREAMMTLKAMEQEEQRAAETAAKEAETI
TAQVPVVPFKVSYL---------------------DTVYFVEPEPEAELEENPQNLTEGI
DNKTHK-----KPKKILNTHTSITGFEKAFEQFATASVQNTQDGMDIGSEEGGPLAPKQT
ELPQETQLDLSPTQGSFTKMK-----------------------------MPTEITKSRR
--HPLSKPPMRSPLSILKQDPAPDKEPSPIIPLESDIK---------KQEHLWQNHSPNF
LAEKAFNAAVSALEPHCAICSLFHPYTQPSKDGASSGMR---------FSPLPRHGSRTR
PLIPEMCFSVGAC----------NSEPPPTN------------------------SHIGE
DGTS-------------------LLLACSSCQM-----------QVH-------ASCYGV
KPDSVGKS--WMCSRCT----KGAWIVECCLCNLRGGAL---KMTVDNQWVHVIC-----
-AI-AVP--------EARFVNAI---DRQPVDVSAVPESRK---------------NLKC
VFCHSKSASQNRGACIQCSQEKC------ATSFHVTCAQIAGVVMTPADWPYVVSVTC-H
KHKKVP---------------------------TKSRRVSKGPESMTL-----GQRV-IG
R---NADGWYYHCTIIGMATQIFYEVSFD-DGSYCDNLHPENVLSHDCLQNGPPDSGE--
-LIVVAMPNGQVANASFVRSHTNIYYQVEFQNQSQQMVKPSELHHLDQELP--KRVRARL
AIP-------GSQDGPS----ADGAQAAKRPRLP-----SGSAACTKTAMETVEPSRPPT
TKSATAPAEHDSISTPPTSQQSTTAAKGFQMDVSTALTDAPSVSTSDPMLTPQSTPFQSM
LNSDPLLSTPSPTPPPQHMVDNYILSTGYVSYMETLLSSHFPQDDESTALY
>gi|50510631|dbj|BAD32301.1|	Mus musculus
-----------------------------------------------RPRRLPPTSEPGG
RGARRRDSVVAPRARAQRTAVTQCGTSLPKIPKTLRGGRTFHPFHSGGVWTSASGAETSV
AIMEVVEVESP---LNPS-------------------------CKIMTFRPSMEEFREFN
KY-LA--YMESKGAH-RAGLAKVIPPKEWKPR----QCYDDID--NLLIPAPIQQMV---
-TGQSGL-----------------------------FTQYNI------------------
--QKKAMTVKE---------FRQL--------------------------ANSSKYCTP-
------------------------------------------------------R-YLDY
------------------------------------------------------ED----
------------------------------------------------------------
-------------LERKYWKNLTFVAP-I---YGADI----NGSI-----YDE-------
------------------------------G-VDEWNIARLN----TVLDVVEEECGISI
EGVNTPYLYFGMWKTTFAWHTEDMDLYSINYLHFGEPKSWYAIPPEHGKRLERLAQ---G
FFPSSSQGCDAFLRHKMTLISPSVLK-KYGIPFDK-------------ITQEAGEFMITF
P--------------------YGYHAGFNHGFNCAESTNFATVRWIDYG---KVAKLCTC
RNDMVKISMDIFVKKFQPDRYQIWKQGKDIYTIDHTKPTPESTPEVKTWLQRKKKLR-KP
PKS----------------------------------LQGNKPLCKRPKPEEDEE-FAEF
SGEEGANPAMGPRHLKVTEK------------------PEKALKLGKLEESSAKEALDTR
IQVDQSLLNDTKLSGKGCISSS-------------VTAEIPPEDNRASAVISPSQLKEGA
DCIPLS----HGHQAGKESHLLK--ILKLE--SPKIPSPLPESNKVLTEGEENDEE---G
HGSNLEPGEIPEALSEERNGLNIPKIIE----------------------GQPKTTKSWR
--HPLGKPPARSPMTLVKQQVASDEELPEVLSIDEEVE--ETESWAKPLIHLWQTKSPNF
MAEQEYNATVAKMEPNCAICTLLMPYYKPDSSKEENDSRWET---A--VNEVVQSGRKTK
PIIPEMCFIYSEE----------NVDYSPPN------------------------AFLEE
DGTS-------------------LLISCAKCFV-----------RVH-------ASCYGV
PSHEVCDG--WLCARCK----RNAWTAECCLCNLRGGAL---KQTKNNQWAHVIC-----
-AV-AVP--------EVRFTNVP---ERTQIDVDRIPLQRL---------------KLKC
IFCR-HRVKKVSGACIQCSYGRC------PASFHVTCAHAAGVLMEPDDWPYVVNITC-F
RHRVNS---------------------------NAKSKTC--EKAISV-----GQTV-IT
K---HRNTRYYSCRVIDVTSQTFYEVMFD-DGSFSRDTFPEDIVSRNCVKLGPPAEGE--
-VIQVKWPDGKLYGAKYLGSNVAYMYQVEFEDGSQIAMKREDIYTLDEELP--KRVKARF
STAS------DMRFEDT--FYGADVIQGERKRQR-----VLSSRLKN------EYVDDPV
------------------------------------------------------------
----------------------------YRTFLKSSFQKK----CQKRQ--
>gi|151942084|gb|EDN60440.1|	Saccharomyces cerevisiae
------------------------------------------------------------
------------------------------------------------------------
--MEIKPVEVI--------------------------------DGVPVFKPSMMEFANLQ
YF-ID--EITKFGI--ENGIVKVIPPKEWLELLEGSPPAESLK--TIQLDSPIQQQAKRW
DKHENGV-----------------------------FSIENE--Y---------------
--DNKSYNLTQ---------WKNL--------------------------AES--L----
-----------------------------------------DSRI----------SQGDF
------------------------------------------------------ND----
----------------KTLKENCRV--DSQQ-----------------------------
---DCYDLAQLQILESDFWKTIAFSKP-F---YAVDE----NSSI-----FPY-------
------------------------------D-LTLWNLNNLP----DSINSSNRR-----
-------LLTGQSKCIFPWHLDEQNKCSINYLHFGAPKQWYSIPSANTDQFLKILS---K
EPSSNKENCPAFIRHQNIITSPDFLR-KNNIKFNR-------------VVQFQHEFIITF
P--------------------YCMYSGFNYGYNFGESIEFILDQQAVVR---KQPLKCGC
GNKKEERKSGPFSNLS--------------------------------------------
-------------------------------------YDSNESEQRGSITDNDNDLFQKV
-----------------------------------------------RSFDELLNHSSQE
LQNLEDNKNP-------------------------------LFSNINMNRPQSSSLRSTT
PNGVNQ----FLN------------MNQTT--ISRISSPLLSRMMDLSNIVEPTLDDPGS
KFKRKVLTPQ----------------------------------------LPQMNIPSNS
--SNFGTPSLTNTNSLLSNITATSTNPSTTTNGNQNHNNVNANGINTSAAASINNNISS-
-----TNNSANNSSSNNNVSTVPSSMMHSSTLNGTSGLGGDNDDNM--LALSLATLANSA
TASPRLTLPPLSSPMNPNGHTSYNGNMMNNN------------------------SGNGS
NGSNSYSNGVTTAAATTTSAPHNLSIVSPNPTY---------------------------
SPNPLSLY--LTNSKNP----------------LNSGLA---PLSPSTSNIPFLK-----
-RN------------NVVTLNISREASNSPISSFVND-----------------------
-----YRSPLGVSNPLMYSSTIND-Y-SNGTGIRQNSNNINPLDAGPSFSPLHKKPKI-L
NGNDNS------------------------------------------------------
----NLDSNNFDYSFTGNKQES--------NPSILNNNTNNNDNYRTSSMNNNGNNYQ--
-AHSSKFGENEVIMSDHGKIYICRECNRQFSSGHHLTRHKKSVHSGE---------KPHS
CPRC------GKRFKRR--DHVLQHLNKKIPCTQ-------------------EMENTKL
------------------------------------------------------------
-------------------------------AES-----------------
>gi|14133223|dbj|BAA74899.2|	Homo sapiens
------------------------------------------------------------
----------------------------------------RIFGASPPRNLAIQKCASRT
AAAMGSEDHGA---QNPS-------------------------CKIMTFRPTMEEFKDFN
KY-VA--YIESQGAH-RAGLAKIIPPKEWKPR----QTYDDID--DVVIPAPIQQVV---
-TGQSGL-----------------------------FTQYNI------------------
--QKKAMTVGE---------YRRL--------------------------ANSEKYCTP-
------------------------------------------------------R-HQDF
------------------------------------------------------DD----
------------------------------------------------------------
-------------LERKYWKNLTFVSP-I---YGADI----SGSL-----YDD-------
------------------------------D-VAQWNIGSLR----TILDMVERECGTII
EGVNTPYLYFGMWKTTFAWHTEDMDLYSINYLHFGEPKSWYAIPPEHGKRLERLAI---G
FFPGSSQGCDAFLRHKMTLISPIILK-KYGIPFSR-------------ITQEAGEFMITF
P--------------------YGYHAGFNHGFNCAESTNFATLRWIDYG---KVATQCTC
RKDMVKISMDVFVRILQPERYELWKQGKDLTVLDHTRPTALTSPELSSWSASRASLKAKL
LRR----------------------------------SHRKRSQPKKPKPEDPKFPGEGT
AGAALLEEAGGSVKEEAGPEVDPEEEEEEPQPLPHGREAEGAEEDGRGKLRPTKAKSERK
KKSFGLLPPQ---LPPPPAHFPSE-----------EALWLPSPLEPPVLGPGPAAMEESP
LPAPLN----VVPPEVPSEELEA--KPRPI--IPMLYVVPRPGKAAFNQEHVSCQQAF-E
HFAQKGPTWKEPVSPMELTGPEDGAASSGAGRMETKARAGEGQAPSTFSKLKMEIKKSRR
--HPLGRPPTRSPLSVVKQEASSDEEASPFSGEEDVSD---PDALRPLLSLQWKNRAASF
QAERKFNAAAARTEPYCAICTLFYPYCQALQTEKEAPIASLGEGCP--ATLPSKSRQKTR
PLIPEMCFTSGGE----------NTEPLPAN------------------------SYIGD
DGTS-------------------PLIACGKCCL-----------QVH-------ASCYGI
RPELVNEG--WTCSRCA----AHAWTAECCLCNLRGGAL---QMTTDRRWIHVIC-----
-AI-AVP--------EARFLNVI---ERHPVDISAIPEQRW---------------KLKC
VYCR-KRMKKVSGACIQCSYEHC------STSFHVTCAHAAGVLMEPDDWPYVVSITC-L
KHKSGG---------------------------HAVQLLR----AVSL-----GQVV-IT
K---NRNGLYYRCRVIGAASQTCYEVNFD-DGSYSDNLYPESITSRDCVQLGPPSEGE--
-LVELRWTDGNLYKAKFISSVTSHIYQVEFEDGSQLTVKRGDIFTLEEELP--KRVRSRL
SLST------GAPQEPA--FSGEEAKAAKRPRVG-----TPLA--TE------DSGRSQD
------------------------------------------------------------
----------------------------YVAFVESLLQVQ----GRPGAPF
>gi|149736989|ref|XP_001492946.	Equus caballus
------------------------------------------------------------
----------------------------------------------MGGSLPGEETETVP
AIMEEAEVESP---LNPS-------------------------CKIMTFRPSMEEFREFN
KY-LA--YMESKGAH-RAGLAKVIPPKEWKPR----QCYDDID--NLLIPAPIQQMV---
-TGQSGL-----------------------------FTQYNI------------------
--QKKAMTVKE---------FRQL--------------------------ANSGKYCTP-
------------------------------------------------------R-YLDY
------------------------------------------------------ED----
------------------------------------------------------------
-------------LERKYWKNLTFVAP-I---YGADI----NGSI-----YDE-------
------------------------------G-VDEWNIARLN----TVLDVVEEECGISI
EGVNTPYLYFGMWKTTFAWHTEDMDLYSINYLHFGEPKSWYAIPPEHGKRLERLAQ---G
FFPSSSQGCDAFLRHKMTLISPSVLK-KYGIPFDK-------------ITQEAGEFMITF
P--------------------YGYHAGFNHGFNCAESTNFATVRWIDYG---KVAKLCTC
RKDMVKISMDIFVRKFQPDRYQLWKQGKDIYTIDHTKPTPESTPEVKAWLQRRRKVRKAS
KS-----------------------------------FQGTSSQSKRPKNEEDGEVLAAV
EGAEGPTSDPHPDDLKASEK------------------PEAAAKLGNTQAPSEEEASASR
MQLDQNSSENIRLSGNSCSSTSIM-----------EETKTENDQACVTIPP------SNP
SEADNS----ASSGHVTSEELDPPKLPWPK--SPESCSSMAESNSVLTEGEESDVE---S
RGSGLEPGEVPAVPSGERNGFKVPTRIE----------------------GETKTAKSWR
--HPLSKPPARSPMTLVKQQATSDEELLEVPSIEEEVE--ETESWAKPLVHLWQTKSPNF
AAEQEYNAAVARMEPHCAICALLMPYYKPDSSNEENDSRWET---K--LDEVVTSGGKTK
PLIPEMCFIYSEE----------NIEYSPPN------------------------AFLEE
DGTS-------------------LLISCAKCCV-----------RVH-------ASCYGI
PSHEICDG--WLCARCK----RNAWSAECCLCNLRGGAL---KETKNNKWAHVMC-----
-AV-AVP--------EVRFTNVP---ERTQIDVGRIPLQRL---------------KLKC
IFCR-HRVKKVSGACIQCSYGRC------PASFHVTCAHAAGVLMEPDDWPYVVNITC-F
RHKVNP---------------------------NVKSKAG--EKGISV-----GQTV-IT
K---HRNTRYYSCRVMAVTSQTFYEVVFD-DGSFSRDTFPEDIVSRDCVKLGPPAEGE--
-VVQVKWPDGKLYGAKYLGSNVAHMYQVEFEDGSQIAMKREDIYTLDEELP--KRVKARF
STAS------DMRFEDT--FYGADIIQGEKKRQR-----VLSSRFKN------EYVDDPV
------------------------------------------------------------
----------------------------YRTFLKSSFQKK----CQKRQ--
>gi|50306059|ref|XP_452991.1|	Kluyveromyces lactis
------------------------------------------------------------
------------------------------------------------------------
--MSYEPDHYE--------------------------------GSVPVFKPDYETFRDFY
KF-MC--EVNKYGM--KSGIIKIVPPEQWVDKVAFPPSAETLQ--KIKIKTPIQQHI---
-SGSKGV-----------------------------FVVQNV--E---------------
--KPKSYNVIQ---------WKHL--------------------------SHD--YKLPE
----GRHSAK------------NEDSSGIEPHQQ-------SNKVR-------SKCLDSF
------------------------------------------------------TL----
-------------DDFEKFRENFNC--DHLE-----------------------------
---QFDDEQRVEFLESYYWKTLNFTEP-M---YGADS----LGSL-----FED-------
------------------------------S-VKEWNISSLP----SILEYLDEK----V
PGVNESYLYAGLWKASFAWHLEDQDLYSINYIHFGAPKQWYSIPQEDSEKFYNFMK---E
QFPEESKNCSEFLRHKMFLVSPKLLQ-SNGIRCNH-------------IVHRQQEFIVTY
P--------------------FGYHAGFNYGYNLAESVNFALPSWLDIG---AKAKKCLC
IDDAVGINVQKLRSNYMHS-----------------------------------------
-------------------------------------PNGGAQKETGKEVQNDKSISSSK
TLEEVLEERPPLKKFKMG--------------------------DSDRSFDSVKSTPEFL
LKTNSDLLDE-------------------------------KANLDNLNNNNNSSIRSTT
PNSQKT----GLYGFGIKKEGAF--NSNTS--ISRVSSPLLSRMMDLSHIVEPTLEDPTL
KFKKKQS-------------------------------------------QFMPLSMAQQ
--QAIFPPPAQNPLP---------------------------------------------
-------APSGQMSPSENAF--FSPSHDHEDN-------------M--IALSLALMANSS
PAFNQ--LPPLNI-----------SNPRPYS------------------------PILQD
------------------------SILSPRPSY---------------------------
NSNVLSYG-------------------------QAGNTKSPLGGFSSSTQLPFIK-----
-RI-QSP--------NRVTLNISRESSRSPVSLSGM------------------------
-----YGNPNAMMVPIPHPYQSSQ-T---STLNQVSTAERSPAVTPPTSP---------S
KNKPAR------------------------------------------------------
----KKAPKQPKAKID--------------PESPTSALAQSKINDEEIMFLDDGS-----
------------------KVYVCQECARQFSSGHHLTRHKKSVHSGE---------KPHS
CPKC------GKKFKRR--DHVLQHLNKKIPCVP-------------------DQDTAPK
------------------------------------------------------------
-------------------------------VGS-----------------
>gi|83766693|dbj|BAE56833.1|	Aspergillus oryzae
------------------------------------------------------------
----MATALDQPLFESVAGPATAAASITPPHSANGKKEVPDGVPSELSDLELDPNAVGVP
EAASVEEEEED---IEPDHYYGG--------------------GKIPVFKPTMDQFRDFQ
SF-IN--KVEKYGM--RSGILKVIPPKEWTDSLP--ALDEAVK--KIRVKNPIMQEF---
-HGSHGT-----------------------------YTQANI--E---------------
--RQRSYNLPQ---------WKGL--------------------------CEESSHQPPA
R---------------------RDTIDKIKPEGPPTPVSPESNPV-------EAK-TEEL
------------------------------------------------------SDGESL
P------------APKPKGRQPKSV--TSRRKHNKGDAIDYVDEEAFKDFDYR---IHDN
---EEYTQERCEELETAYWKSLMFNNP-L---YGADM----PGSL-----FDE-------
------------------------------NITTSWNVARLP----NLLDVLGQK----V
PGVNTAYLYLGMWKATFAWHLEDVDLYSINYIHFGAPKQWYSISQEDAPKFEQAMK---S
IWPSDAKNCDQFLRHKTYLVSPSLLKSQYGITVNR-------------LVHYEGEFVITY
P--------------------YGYHSGYNLGYNCAESVNFATEKWLDYG---RVAKKCHC
ESDSVWIDVDEIERKLRGEATPEYYP----------------------------------
------------------------------------------------EFESDLDEFEGA
SDLLTPPRSVPEKSNR-----------------------------GRKRKHDGDTTKAKR
MRVNVHVPRK--------------------------------------------------
--------------------------------IPCVLCPND------------------L
DYEDLLPTEDG------------------------------------------KNHAHRR
------------------------------------------------------------
-------------------CALYTEETSILRDETGKE--------V--VCDIDKIPKARM
GLKCLFCREVRGA-----------------------------------------------
---------------------------CFQCNF---------------------------
------------------------------------------------------------
------------------------------------------------------------
--------------------GKC------TRSYHATCALLAGVQVEQGEIAVI-------
------------------------------------------------------------
----ADDGIHYSIPSVDL------------KCKYHRQKKPSWMTGGDSPDFDRK------
----------------------LIESAQRMVAGDLVQFQADKEINGAVVLE---------
----------NRPAERT-------LLVKVLPRG---------------------------
------------------------------------------------------------
---------------------------------------------------
>gi|118785123|ref|XP_314337.3|	Anopheles gambiae
------------------------------------------------------------
-------------------------------------------------MNHHNNPHRPH
ISLDKCDDFQF---NVP--------------------------PEAPVFEPSEEDFKNPL
VY-IN--KIRPTAE--KFGICKIRPPSSWQP-----PFTVDVE--KLTFTPRIQRLNELE
AETRIKLNFLDQIAKFCELQGTTLKIPMVERKPLDLYTLHKIVNQEGGLEVVTKERKWSK
VACRMGYQQGKSVGSNLRTHYDRL-LYPFDVYRSGKVVDLANIDPEPSEDCEYEPHCIES
RQQVQPPMTAARRSQRFAQQQNNSKPSSTTGSSAGGSVRGSSDEMSPSKKELRHRSMLEF
ASKLAAAARDQAATNGGASKEEKVGVGGTHGYDPMAKYICHMCNRGDVEESMLLCDGCDA
SYHTFCLMPPLQDIPKGDWRCPKCIVEEHSKPVEAFGFEQAQREYTLQQFGEMADQFKSN
YFNMPVHLVPTELVEREFWRIVSSIDEDVTVEYGADLHTMDHGSG-----FPT-------
-------------------KSSSLSSTDQEYAESSWNLNNLPVLDESILGHINAD----I
SGMKVPWMYVGMCFATFCWHNEDHWSYSINYLHWGEPKTWYGVPGSRAEDFELAMK---S
AAPELFHSQPDLLHQLVTIMNPNILM-NANVPVYR-------------TDQHAGEFVVTF
P--------------------RAYHAGFNQGYNFAEAVNFAPADWMKMG--------REC
VNHYSKLR-----------RYCVFSH----------------------------------
----------------------------------------DELVCKMALEPDRLNLGIAT
--------------------------------------------ACYIDMAEMVDTEKKL
RKNLLEWGVS------------------------------NAEREAFELLTDDARQCEIC
-------------------------KTTCF--LSAVNCKCTKNLACLRHFAELCECPPEN
HTLKYRYTLDELPLMVQK--------------------------------LKVKAESFEK
----------------------------------------------------WLFRVRDV
L------------DPSVASSITLEELQSIAHEAESQKFPNSVILER--LNLSILEAQKCI
TVIQQLDINKIRT-----------------------------------------------
-RTR-------------------NSLECAKYKL------------------------SMD
ELELFINE--INNLRCV----------------IREGDSVRELQRIGQEWLRQAD-----
-KAL-----------KLRF---------KDTNVQQLN-----------------------
-----QLIEEGNALCIELPQIVEL-R-DRLTQYK-------------------------W
YREVRT----------------------------LRENTVDRLSLEEI-----KKLI---
----NEGMRILPHTVLEKELSQLHGIMLQ--------IVDWEQSANQCFKTETQHKIS--
-EIDSLLERAQ---------NIEEFLPLAGQLKDALHKSKEWLHAIE-------------
TLES------SKNYNF---FHTLQNLANRAKLLP-------------------VEVE---
------------------------------------------------------------
---------------------------------------------------
>gi|149633755|ref|XP_001507384.	Ornithorhynchus anatinus
------------------------------------------------------------
------------------------------------------------------------
----MASESES---LNPS-------------------------ARIMTFYPTMEEFRNFS
RY-IA--YIESQGAH-RAGLAKVVPPKEWKPR----TCYDDID--DLVIPAPIQQVV---
-TGQSGL-----------------------------FTQYNI------------------
--QKKAMTVRE---------FRKI--------------------------ANNDKYCTP-
------------------------------------------------------R-YSEF
------------------------------------------------------ED----
------------------------------------------------------------
-------------LERKYWKNLTFNAP-I---YGADV----NGTL-----YDK-------
------------------------------H-VDEWNIGRLN----TILDVVENESGITI
EGVNTPYLYFGMWKTSFAWHTEDMDLYSINYLHFGEPKSWYSIPPEHGKRLERLAK---G
FFPGSAQSCEAFLRHKMTLISPSILK-KYGIPFDK-------------VTQEAGEFMITF
P--------------------YGYHAGFNHGFNCAESTNFATLRWIEYG---KQSVLCSC
RKDMVKISMDVFVRKFQPERYKLWKAGKDVSVIDHTLPTPEAAEFHRGEFQ---------
-------------------------------------QKSKNGKDCGDEMEAAGAKDEVD
QKRSLAKHRIGTKRHRVCLEVPQEVSESEAFPKEELNPGQFEVEERQTTGVHAVKPTSEP
VRQGEDDPTLPDYPDSTEVKFEELKN---------VKLEEEEEEEEQEAAALDLSVSNSV
NLAAAGRGPAPPPSKESGTSGFRCKRGADSGSSDSETAEPLPKRTQSPPGVLTVHSYAKG
DGTAADSEQTSGKKASSTANMSEQELAEVAEEYMR---------------SLEESKKSKG
RRQPLSKLPRHHPLVV--QDCVSDDEMAEQLTPEEEAE--ETEAWAKPLSQLWQNRPLNF
EAEKEYNQAMAKQPPHCAVCMLFQTYQQSECGGQSQNCGS--------APGAAPGKLRTK
PLIPEMCFTTTGC----------NTDLNLST------------------------SYLEE
DGTS-------------------VLIICKKCSV-----------CVH-------ASCYGV
SPERATED--WMCSRCA----ANALEEDCCLCSLRGGAL---QRANDDRWVHVMC-----
-AV-AVL--------EAKFVNIA---ERSPVDVSKIPLLRF---------------KLKC
IFCK-KRRKRIAGCCVQCSHGRC------PTSFHVSCAQAAGVMMQPDDWPFVVFITC-F
RHKVPS----------------------------YAERTKGALQDISA-----GQKV-IS
K---HKNGRFYQCEVVRLTTETFYEVNFD-DGSFSDNLYPEDIVSRDCLQLGPPPEGE--
-VVQVRWTDGQVYGAKFVASHAIQMYQVEFEDGSQLVVKRDDVYTLDEELP--KRVKSRL
SVAS------DMRFTEI--FTEKEVKQ-EKKRQR-----VINSRYRE------DYIEPAL
------------------------------------------------------------
----------------------------YRAIME-----------------
>gi|126335747|ref|XP_001371772.	Monodelphis domestica
------------------------------------------------------------
------------------------------------------------------------
--MEAAEVDSP---PNLS-------------------------CKIMTFRPSMDEFREFN
KY-LA--YMESKGAH-RAGLAKVIPPKEWKPR----QRYDDID--NLIIPAPIQQMV---
-TGQSGL-----------------------------FTQYNI------------------
--QKKPMTVKE---------FRQL--------------------------ANSDKYCTP-
------------------------------------------------------R-YLDY
------------------------------------------------------ED----
------------------------------------------------------------
-------------LERKYWKNLTFVAP-I---YGADI----NGSI-----YDEARVRRVP
LMDFENGCNRGCSNNLWNCQLRDGNGIKQLG-VDEWNIAHLN----TILDVVGEECGISI
EGVNTPYLYFGMWKTTFAWHTEDMDLYSINYLHFGEPKSWYAIPPEHGKRLERLAQ---G
FFPSSSQGCDAFLRHKMTLISPSVLK-KYGIPFDK-------------VTQEAGEFMITF
P--------------------YGYHAGFNHGFNCAESTNFATVRWIDYG---KVAKLCTC
RKDMVKISMDIFVKKFQPDRYHLWKQGKDIYTIDHTQPTPESTPEVKLWMQRKKIRKPSR
S------------------------------------LQHTRSRSKKLKTPEDEKISAMV
IGAEVVATESTTDDFKVNEK---------------PVEKKGLVNTGISSGEETTIKGMQV
DQSLSDNVKVSGSNGVSTSFHSDS-----------IEQEIKCEKDKVDSSIPSSDLMESS
ASMPLA--AECIIEDNLKSESDCVSRPKSCDSVSS-EAEILEKEENSSISTEEDDSDLES
SESVLEPGEIPAKTKGERNDFKIPSFCNRRAE------------------GEPKTSKSWR
--HPLSKPPARSPMTLVKQQAGSDEELPEVPSVEEEVQ--ETESWAKPLVYLWQSKAPNF
VAEQEYNAAVAKMEPYCAICTLLMPYYKPDNSNEDSFCKWESK-----SNEVTSALEKTK
PLIPEMCFIYSEE----------NTEHSPSN------------------------AFIEE
DGTS-------------------LLISCAKCCV-----------QVH-------ASCYGV
PSQDIRDE--WLCSRCK----RSAWTAECCLCNLRGGAL---KQTKNKKWAHVMC-----
-AV-AIP--------EVRFVNVT---ERTPIDISRIPLQRL---------------KLKC
IFCR-QRVKKVSGACIQCSYGRC------PASFHVTCAHATGVLMEPDDWPYVVNITC-F
RHKINQ---------------------------NVRSKPC--EKAITV-----GQTV-IS
K---HRNTRYYSCRVIEVTSQTFYEVVFD-DGSFSRDTFPEDIVSRDCLKLGPPAEGE--
-VVQVKWPDGKLYGAKYLGTNVAHMYQVEFEDGSQIAMKREDIYTLDEELP--KRVKARF
STAS------DMRFEDT--FYGADIIQGEKKRQR-----MLSSRFKN------EYVDDPV
------------------------------------------------------------
----------------------------YRTFLKSSFQKK----CQKGL--
>gi|58270824|ref|XP_572568.1|	Cryptococcus neoformans
MSTSETQIPALPSSGGRPSHPSSSSSAASISNTSIPSVVEQQNGIPIPPTNIPEEAVSGT
VTASTSDTPQASRNSQVPTEENTKSIDLQEPTVPEKNASVEEPSGVESSEVGGEDQEIKE
GPKFIQPDHFSPLTNNPNGSRPARGIPNIGDGWLSPEDDPHALRGIPVFKPSMEEFLDFE
GY-AR--KTTAWGQ--YSGIVKVIPPAEWIESVP-PITKSSLA--SVRVTDPIQQNL---
-IGSSGL-----------------------------FRIANVVRN---------------
--KRRPLTVEE---------WFKK--------------------------CKDKKFSGPG
PKDVGSTTNRDSKEAEERRQRVRDDMRKEKEKRREKRLAAEANRARKATGIEDIK-EEEE
------------------------------------------------------VNGQAP
SVLDRKDEASTEFVNNPQECQPASL--EPDSR-TKGIMVEKSINSWYESFDPKEDWLPEN
TRREDYSLEACVALERRFWKNMGLGEPSW---YGADM----EGSL-----FMD-------
------------------------------E-KTPWNVAHLP----NLLNRWDLRH---L
PGVNAPYLYFGMWGASFAWHVEDMDLFSINYIHFGAPKFWYAIPQQQAERFERILQ---G
YFPEDARNCDQFLRHKSFAVSPYRLA-SDGMRVNM-------------LVHNQGEFVITY
P--------------------RGYHAGFNMGFNCAESVNFALDSWVELG---RRAKACNC
VNHSVRIDVDEMLAK-DAVRFQGEEELLSAIAEERNKKRQHRRP----------------
-------------------------------------SAGDNHTPRKRAKPDSQTPSGGL
VSSHTP-----------------------------------IVIEATDQSKPVKVPGKRT
PKAVIDISSN------------------------------------------QQRAKANS
IKDPNS--------------------------FPCLFCP-GFARDDLLPVFDPSDS----
----VKARWKP---------------------------------------RHGEVMAHHS
------------------------------------------------------------
-------------------CALAIPGVGIEDREVPGGLGTF-------VVGVENVESARW
KLKCLLCKDKKLQ-----------------------------------------------
-----------------------KTGAKIQCTK-------------------------GK
CPRAFHVS----CARESDVANLKIWEVETPMLPREGE-----PPLPEGAEVPTMI-----
-DI-KVELLCPQHNPEVKEKLEQRKAETFRDKVMSIPSGSK-------------------
-----IKIKVRTGASLEYTLVEAR-----ETTQQVYVHDAQG------QFPTPIPPLQ-V
SHRMSY------------------------------------------------------
------DLGLHRQTHQSVPQQVFYPQPPSQEHQPLHSIPHPPISRRPHHPIPPSDTSQ--
-RVANHQAPHDSYYPRPASVPMLHRYHHQPLQPSYPSRYQTPPQTHYPSHPY-PRHEPHI
QPPAPSAHPMNNQATDASHFHGQMYEPYRRHSAP--HPVYPTHFMSSVNSVTAEQTRVWD
------------------------------------------------------------
----------------------------RKASAPNGAVHPSIPDGYRQGYY
>gi|125805606|ref|XP_693231.2|	Danio rerio
------------------------------------------------------------
------------------------------------------------------------
-----------------------------------------------MYGRYTQELGAYA
KEEAA--RLREDG-----GLRRTTSVRGQAPE----LLEYEKD------PCAKCQVC---
-TSRCKK-----------------------------FLISRV------------------
--GEDWIFLIL---------LGLL--------------------------MALVSWAMD-
-------------------------------------------------------YTIAF
------------------------------------------------------CQQAQK
W-----------------------------------------------------------
---MYRGLHSNMLLQYLAWVTYPVVLI-T---FSAGF----TQIL-----APQ-------
--------------------------------AVGSGIPEMK----TILRGV--------
--VLKEYLTFK----TFVAKVIGLTCALGSGMPLGKEGPFVHVASLCAALLSKFMALFGG
IYMNELRNTEMLSAACAVGVGCCFAA-PIGVLFSIEVTSTFFAV----RNYWRGFFAATF
SAFIFRVLAVWNKDEETITALFKTRFRLDFPFDLQELPAFAVLGFVSYLCLFAFPKQCSC
RKDMVKISMDVFVKKFQPERYELWLEGKDNAPIDHSKPTPEAAE----------------
-------------------------------------FLGGEAGAQELRIENQSNEGQKK
---SLAKQRIGTKRHRVCLD-----FPEEVLPKTETNDEAEYGKKGRLTPYTEQCKEYTE
LKHEDRTLPL--MGSTSLKMLPGS-----------RSAEFSENVRGAGFSDADLDAKATS
HISACA----QPFPKHHLSIASVPTVPHCLSAVPRVSTKPGVASLLFHRTLSPTDALQVH
SYAAKAALCKPQTPSPEKPREDLHIPDISLDVRPNTPTPPPDTPEHEIE-GEKENNSMKR
KLQPLSKLPRLHPLL---RENSSDDEIQEPTAEPEETD-----PWAKILAPMWQSRQRNF
QIEKEFNFRMGLHPPYCAVCSLFHTYNESDVISLGG------------FAAVGGNPQRTK
PLIPEMCFTSSSE-----------GHLSTPN--------------------------LEA
DGTS-------------------QLISCSVCSV-----------RVH-------TSCYGV
SQDAKLDS--WRCSRCE----ANAITQDCCLCSLRGGAL---QRANNDKWVHVLC-----
-AV-AVL--------EARFVNIA---ERRPVDLSTIPFQRF---------------KLKC
QFCR-KWVKKTTGCCVQCSHGRC------STSFHATCAQAAGVQMHPDDWPFVVYFTC-W
RHKGGT---------------------------HIERNMA-SMRELEK-----GQKV-IC
K---HKNGRYYHCEVVELTKATFYEVIFD-DGSFSDNLFPEDIVNRDCTRHGPPSEGE--
-VVQVQWTDGLIYGAKFVSDHIIPMYQVEFEDDSQLTVKREDVFSLDEELP--KRVKSRL
SVAS------DMRFKGV--FVEKEVKQ-DSKRQR-----VINSRYRE------DYIEPAI
------------------------------------------------------------
----------------------------YRAILE-----------------
>gi|45201213|ref|NP_986783.1|	Ashbya gossypii
------------------------------------------------------------
------------------------------------------------------------
--MSGNPDHFE--------------------------------GGVPVFRPSWEEFQDFY
KY-MF--LIDEYGM--KSGVVKIIPPREWVERLGERPGVEQLR--RIHIRSPIQQHV---
-SGSKGV-----------------------------FVVQNV--E---------------
--RQKSYNIIQ---------WKDL--------------------------AQD--YQLPD
MRGYGGSLSR------------SAAAGGARP--R-------PSNIR-------TRTQDSF
------------------------------------------------------SD----
-------------EDFREFQEHYNV--EGLA-----------------------------
---QYDDESFLRGLENYYWKTLNFTEP-M---YGADT----LGTL-----FPD-------
------------------------------S-LHQWNVSRLP----NLLDHLEEK----V
PGVNQSYLYAGLWKASFAWHLEDQDLYSINYLHFGAPKQWYSIPQEDSHKFFKFMQ---E
QFPEESAQCREFLRHKMFMVSPKVLE-RNGIRCNS-------------IVHRQHEFMVTY
P--------------------YGYHSGFNYGYNLAESVNFALESWLPIG---EKAKKCMC
VDDSVGIDIQKLKSAY----FRSLQE----------------------------------
-------------------------------------DRAGSADPEPPRKRLKQEPNTSS
FVQAPILDTG----------------------------------DSLKSFNELINHSAYE
LQAMEDNPNQ-------------------------------------------RSIRSTT
PNQY---------------------FSNPS--ISRMSSPLLSRMMDLSNIVEPTLEDPTL
KFKRKV--------------------------------------------VAQDTSNAMA
------------------------------------------------------------
-----PNPVSGVGAPVTSVC--VGPPALNNLHEESV------------LALSLASMANSG
NSSPRNALPPLNS------AVGNSRPYTPTG-----------------------------
-----------------------DAILAPRPSY---------------------------
DQNPLSYY----------------------------------STQTTKSPMPLFK-----
-RI-NSP--------NRVTLNISRESSRSPISFG--------------------------
-----------------SEYGK-------PPLSKPHPLNAGAVNLTSLNQVSTIERNI-P
SHRDRS------------------------------------------------------
----AKAYHGDKVNIHGVSSGKFVGHQIN---DSLALLNDDALTNSVLPGAGRPERAT--
-SPTSKISAEEIIISDKGKAYVCQECQRQFSSGHHLTRHKKSVHSGE---------KPHS
CPKC------GKKFKRR--DHVLQHLNKKIPCVT-------------------EKHEDPA
------------------------------------------------------------
-----------------------------------------------TATA
>gi|119894919|ref|XP_584880.3|	Bos taurus
------------------------------------------------------------
------------------------------------------------------------
---MGSEDHGA---QNPS-------------------------CKIMTFRPTMEEFKDFN
KY-VA--YIESQGAH-RAGLAKIIPPKEWKPR----QTYDDID--DVVIPAPIQQVV---
-TGQSGL-----------------------------FTQYNI------------------
--QKKAMTVGE---------YRRL--------------------------ANSEKYCTP-
------------------------------------------------------R-HQDF
------------------------------------------------------DD----
------------------------------------------------------------
-------------LERKYWKNLTFVSP-I---YGADI----SGSL-----YDD-------
------------------------------D-VAQWNIGNLR----TILDMVERECGTII
EGVNTPYLYFGMWKTTFAWHTEDMDLYSINYLHFGEPKSWYAIPPEHGKRLERLAI---G
FFPGSSQGCDAFLRHKMTLISPIILK-KYGIPFSR-------------ITQEAGEFMITF
P--------------------YGYHAGFNHGFNCAESTNFATLRWIDYG---KVATQCTC
RKDMVKISMDVFVRILQPERYELWKQGKDLTVLDHTRPTALSSPELSTWSASRASLKAKL
LRR----------------------------------SHRKRSQPKKPKPDDPRSPGEGA
AGVALLEEAGGSTKEEAAPEADPEEEEEEAQLLPQGREAEGSEEDGRGKLRLAKAKSDRK
KKSYGSLHPHHPLLPPPPSS---------------QFTEEAPLLDIPGPAPGLEAAEESP
LPPPLN----VVPPKAPGEEPEA--KPRPV--IPMLYVVPRPGPT-GNKGRVSCQQAS-E
HFAQKGPTWKEQATPMELTGPEEESGAS------------EGQNPSTFSKLKMEIKKSRR
--HPLGRPPTRSPLSVVKQEASSDEESFPFSGDEDVGD---PEALRSLMSLQWKNKASNF
QAERKFNVAAALTEPYCAICTLFYPYSQSLQTEKEAPQAALGEGSS--AIPPSRSGQKTR
PLIPEMCFTASGE----------NTEPLPAN------------------------SYIGD
DGTS-------------------PLIACAKCCL-----------QVH-------ASCYGI
RPELVNEG--WTCSRCT----AHAWTAECCLCNLRGGAL---QMTTDRRWVHVIC-----
-AI-AVP--------EVRFLNVM---ERHPVDISGIPEQRW---------------KLKC
VYCR-KRMKKVSGACIQCSCEHC------STSFHVTCAHAAGVLMEPDDWPYVVSITC-F
KHKSGG---------------------------HSVQVMR----AVSL-----GQVV-IT
K---NRNGLYYRCRVIGTTTQTFYEVNFD-DGSYSDNLYPESITSRDCARLGPPPEGE--
-FVELRWTDGNLYRAKFISSVTSHIYQVEFEDGSQLTVKRGDIFTLDEELP--KRVRSRL
SVST------GAPQESV--FSGEEVKAAKRPRVG-----TPRA--AE------DSGRNPD
------------------------------------------------------------
----------------------------YPAFMESLLQAQ----CWPGAPY
>gi|68485403|ref|XP_713379.1|	Candida albicans
------------------------------------------------------------
------------------------------------------------------------
----MSFDKRL---LTP--------------------------CPVLT--PTDQEFNDPV
GY-LSSDKVSKLGA--TYGLVKIVPPPNWKPS----FHINPDF--KFHVRKQVLSDL--G
ITTRSRD-----------------------------FFRENI------------------
---NRFLKMRR---------KRQLKLYFNVQGTRVYYYDLYREVENLGEPMDKEKWEKL-
--------------------------GARFGVKASALEREYDSTIKYYATYLHTNCTYDF
----------------------------PESDSEDEYDSCLVCGQHDHPSETLLCDNCDN
PYHMKCLNPPLESVPATSWYCDKCLIGTGEYGFDEDVDVKYTIPEFYKMCQDFDAKFIRD
Y--NQNNPLSVDDIERKFWSFVDAEKSDLEVKYGADIHNLRPGEVS---GFPM-------
---------------ADTPSLDTTDPAIQYYINHPWNLNKLPFSNGSLLNFINTS----I
SGMTIPWIYIGSLLSTFCWHVEDHYTLSANYCHFGATKKWYGIPSSFADKFEKLMR---D
SAPDLFKRQPDLLHQLVTLMSPSKLV-EHGIPCVY-------------ADQNSNEFVITY
P--------------------LVYHAGFNCGFNFNEAVNFAIDEWLEFG-----------
-----EKSVNDYRPIKKENVFNHYEL----------------------------------
-------------------------------------------------LENILSRFNAK
HDVSL---------------------------------------DLVKRSLWSFERYVSR
LEELLAQLKD--------------------------------------------------
--------------------------------KSTVEYKPSVDNNDEDDLCDSCKTHIGF
QYFVLEPENSKQL-------------------------------------LTPDASPQEI
------------------------------------------------------------
-------------------------ETKPNKNEEAKKVANS----Q--ASHDLASLNERK
AMVDEFN-----------------------------------------------------
-----------------------SLIEKAKKDV---------------------------
---DNDES----------------------------------TKVRRSKRIHSLK-----
-EK-EVP--------QRPT-------KRAKKNII--------------------------
-----KKKAAQSKLCSEC--------------------------------------VCPM
KGKSIH-----------------------------------------------GKLV---
------------------------------------------------------------
--------------------------------------LRKQLSTLKELIE---------
----------ETKMNLV-------------------------------------------
------------------------------------------------------------
---------------------------------------------------
>gi|118103351|ref|XP_001233692.	Gallus gallus
------------------------------------------------------------
------------------------------------------------------------
---MGSENPSP---QNPG-------------------------CKIMTFRPTLEEFREFG
KY-VA--YIESQGAH-RAGLAKVIPPKEWKPR----KTYDDID--DMIIPAPIQQVV---
-TGQSGL-----------------------------FTQYNI------------------
--QKKPMTVGE---------YRRL--------------------------ANSEKYCTP-
------------------------------------------------------R-HQDF
------------------------------------------------------ED----
------------------------------------------------------------
-------------LERKYWKNLTFVSP-I---YGADI----SGSL-----YDT-------
------------------------------D-VEEWNIGNLN----TLLDMVEHECGIII
EGVNTPYLYFGMWKTTFAWHTEDMDLYSINYLHFGEPKSWYAIPPEHGKRLERLAK---G
FFPGSSQGCDAFLRHKMTLISPSILK-KYGIPFDR-------------ITQEAGEFMITF
P--------------------YGYHAGFNHGFNCAESTNFATLRWIDYG---KMATQCTC
RKDMVKISMDVFVRVLQPERYDLWKQGKDIAVLDHMKPTALTSPELDAWNETKADLKAKL
LRR----------------------------------SHRKRSQPRRHKTEDQKSLGDVM
AIETALEDVKVKEELKRGPD-----LEEEERSKVIEGEASGVSSDSKVKARPPKVKGERK
KKHLFHQHQH-------HLQTSQK-----------RQQQQHGRQYPQQHLQHPQQTRACX
PLPSTL----SSPRRHQLRKMTL--SLGLS--FPCFMWFHGPKKWCLTKSTCPASRH--L
SSLRLRRVLVGGSRQSLWKSLXKK--------------------------RRVQNQKIQR
LLQRSDKGRQHALLILLLFQKXRWRXRKVVVTHXANHQ--------PAPHCQWLNRRPRV
MRKR-FHFLGRKIXVTQRLXNLYFPSSGRIEHLISQLKG------N--SMQLLPXVSHTV
LSVPSFTHIPSPYRWIKKLSQPLXGRPPLLF------------------------TFLSA
DRRQ--------------------SLXSQRCALPQVEKTQSPFLQIHILEKMEPVPXYPV
-PNAACRF--MLAVMEY----VQIWXMKAGLAH---DAQ---PMHGQRNAACVIS-----
-GE-ELFRXPLMGGGSIXFVLSL---SLRPVFSMXXSVILW----------------ISL
LFQ--SKGGNXNVCTVESGXRKC------LVPASSAPTSTAPL---PSTXPAHTLLVCPW
SPMTGP---------------------------TLCPLPASNTKQPTRIFSFEGRXP-LD
RLXSQRTGMDSTTDVKSLAXQHRLSMKX----TLMMVHTVTTFTQKALLAETASSWDP--
-LQRVRWFNCSGQMESSIRPSLLQLRSVRFIRLS-LKMARNXWXSVVIFIPWRRSFRREX
SLAC------PSALGPLRKMYFREMKX-EQPSVPGWGMQGILKSMDK------TQITWPL
------------------------------------------------------------
----------------------------WRACCRHSTNLELRATCF-----
>gi|50293745|ref|XP_449284.1|	Candida glabrata
------------------------------------------------------------
------------------------------------------------------------
-------MEVV--------------------------------DGVPVFRPAWEEFKDFM
GY-ME--KIRPHGM--ASGIVKVIPPREWLDRAGREPREDLLR--EVRIRNPIQQHV---
-SGSKGV-----------------------------YMISNV--E---------------
--KNKTYNMIQ---------WKDL--------------------------SYD--FRVPD
----DPSSLK------------NKSEESIQDNERSQQRRRSSSGIK-------LKNCDSA
------------------------------------------------------TE----
-------------EDFQNFMKEYNA--ENIR-----------------------------
---DFDDEERLKFLESYYWKTLNFTTP-L---YGADS----SGSI-----FPS-------
------------------------------D-LEEWNVAKLP----NVLSHIDQD----I
PGVNQAYLYAGLWKASFTWHLEDQDLYSINYIHFGAPKQWYSIPQEDHEKFYEFMK---E
KFPEEASKCKEFLRHKMFLVSPKVLK-ENNIKCNK-------------VTHYEHEFIITY
P--------------------YGYHAGFNYGYNLAESVNFALEDWLEIG---KKAGKCRC
ISDSVEVDVDKL-----AENWSNFKKKREIE-----------------------------
-------------------------------------DPETEDSPQKKRKSSTVDSNETI
SNVSATKEDDEVKNEDNDDNSKLIKDVKKEVTDSNEDDLNASVDVQRQSNDNTFGDNSNP
ATNIKMESNKTKIEANVPGVAKKL-----------RGFDELLNRSPQNSPRMETSLKNDP
FFARDS----PLRSNSPGTNL----FFNQS--IQRMSSPILSKMIDLSNIVEPTLDDPTL
KFKRKTNLPSQLIGNSNISSP-----------------------------LLQNIQDQQN
------------------------------------------------------------
--QQQQQQRSQNGTPLSNLS--FGPMRSGLGSNPVLLDNNDDN--M--LALSLTSMANSR
PSSPRLHHINIPNEANSKMKSGSNDTVNAAS------------------------NFVTS
G----------------------SNVQQGMSVV-----------------SPKPVPYYGN
QFERTFNS--MPSPI---------------------------PMSPGGSNMPFIK-----
-RL-KSP--------NIVTLNISREGSKSPVSLQNEV--R--------------------
-----SPLGLNTTLSYPIPTEKQL-S-NLNPVNNSNYQAASPALMDDKNNINPNQNMNSL
LDMGLS---------------------------AFQNSPSNGLRQISS------------
-------ETYESSPLMSLAAAANKDIEL--TNSMMRPSRSKTKLPTDKAR-SKSKSVE--
-AQGPKFEKGEVILSDSGKIYVCQECKRQFSSGHHLTRHKKSVHSGE---------KPHS
CPKC------GKRFKRR--DHVLQHLNKKIPCIP----GVGSSAGTDMVQVMKDDDRIME
------------------------------------------------------------
---------------------------------------------------
>gi|150951254|ref|XP_001387545.	Pichia stipitis
------------------------------------------------------------
------------------------------------------------------------
-MSYVNDPDLV---VTPSYYS----------------------GGVPVFAPTMKQFEDFY
KF-NK--AINKYGM--ESGIVKVIPPREWGASLPRAYTRKNLS--RANIKNPIVQQI---
SITGAGV-----------------------------YSIQNI--E---------------
--KQKKYNIFQ---------WKEL--------------------------SERSNYQPPT
H-------------------RLSDLIPNSTPNSTPSSNANYSTNF--------NTSTNDV
------------------------------------------------------ND----
-------------SPSKRLRHHHHY--DPL----------YNIDS---------------
---SQFTPERCEELEKTYWRTLTYAEP-M---YGADM----LGSI-----FPS-------
------------------------------N-FKSWNVDHLP----NILDLMDTR----L
PGVNDAYLYAGLWKATFAWHLEDQDLYSINYLHFGSPKQWYSIPQAESGRFFSLMK---E
TFTDDYNHCHEFLRHKTFLVSPSFLD-KHGIKYNK-------------IVHNEGEFMITY
P--------------------FGYHAGFNYGYNLAESVNFALDDWFPYG---EVTKKCEC
ISDSVGINVKQLYCKFQGIPYKSE------------------------------------
-------------------------------------SDGIDTEATETEAETKVSPAENT
ASIT---------------------------------------------PKETKQTKQTI
KNAN--------------------------------------------------------
--------------------------------FECYLCPNIFNSAQISSNPLFELVSTDL
HDS-----------------------------------------------KTHQYYKVHR
------------------------------------------------------------
------------------ICAGMFPKELKTSTNSAGDE-------I--VLGLTNISKNQM
KLKCKVCNKGASK-----------KEAAVHG-----------------------------
--------------------------ACFQCSY---------------------------
------------------------------------------------------------
------------------------------------------------------------
--------------------PKC------TRGFHGTCGVSDGVIYSLENH----KPLC-K
YHRSKK------------------------------------------------------
----VSSDRYDKLSKISGDNGSWVQFSFN-TNQYFGLVLTNNLDEHTLTLLVYPNLND--
-RIEVPYD---------------------------FVLTGATLNQLD-------------
----------NSAFIN--------------------------------------------
------------------------------------------------------------
---------------------------------------------------
>gi|91085047|ref|XP_974381.1|	Tribolium castaneum
------------------------------------------------------------
------------------------------------------------------------
----------------------------------------------MVFRPTWDEFKDFS
QY-IQ--HMESKGAH-KAGLAKVIPPPEWVPR----KSGYAIDTLDVTIPAPICQVV---
-TGKQGL-----------------------------YQQINI------------------
--QKKSMTVQQ---------YCEL--------------------------ANSERYATP-
------------------------------------------------------R-HFDY
------------------------------------------------------ED----
------------------------------------------------------------
-------------LERKYWKNITYVAP-I---YGADV----SGSL-----TDD-------
------------------------------T-VNEWNINRLG----TILDYVNEDYGISI
EGVNTAYLYFGMWKTTFAWHTEDMDLYSINYLHFGAPKTWYSIPPEHGRRLERLAN---G
FFPSSYKTCQAFLRHKMTLISPQILK-QYSIPYNK-------------ITQEAGEIMITF
P--------------------YGYHAGFNHGFNCAESTNFACERWIEYG---KRASQCTC
SKDMVKISMDTFVKRFQADRYEMWLKGEDIGPHPE-------------------------
-------------------------------------EPNKQVAAPLPLPQDILCNKNND
SLPAGLIE-GQLKKAKKAGRMMNYSQDYSMVDFPAELQLQLMEEDDMGYVNGEFPPDEQQ
LEVLEDIWLKAGEIEAEDASICDAGYRVTNRRKFLAKKRKPKEPRPRGRPPKKRTKDGEE
EPESNELTGIYAPCNSQSKKVCGQ-IVAPVDTSELVKSLVAQETNKLLHHKKHKHKHKKC
KHHQKTATQTSPDTANSEVKKEIDDII-----------------------RKAHEEHEQT
IMQQEEKPPVKPSLLSELKAYRKVKDPTDQFRMEPKVQ-----------TIHTSKGTITV
LESRPVVPPPPETKPPERKSLYEDAFLNFLTAKTDKPVPDLAGGSMPNLSEPEPVLIERS
EQMPKLEPVPVEE----APTVQVNPNPVPPTYYQRKPNLIWSNHKYYTVNHCTTTTYLNN
DRFY-------------------PMTNNPIVLL---------------------EKATPK
TPDSDSGS-DCSCESCS-----------CSECDE--------QVENSSNSINVVP-----
---------------QNKKLNLEQLKQLTQRVLGVENGTKFYNDKIV---------ALKK
MLTMRRRGRPPKNNSLEKRNNNNT-M-TDFHSYNCKLLEKIAKLTPLEAKVKLVDVLNNF
TNDVQN--------------YLKAGLPLANVSALSLDEPPPNDETSERFPVKLNEFV-WA
K---HLNGRFYKAKIVDIKIVTYFCVYFPLDQSFCKDVELADLVGWDLKKV--PIVGQ--
-KLRVRWKDGTICVAEFLGKNNSSIFTVMFEDESRLELHRDSI-----------------
-------------------VAASESISKKIASLK--------------------------
------------------------------------------------------------
---------------------------------------------------
>gi|73977239|ref|XP_539647.2|	Canis familiaris
------------------------------------------------------------
------------------------------------------------------------
----MASESET---LNPS-------------------------ARIMTFYPTMEEFRNFS
RY-MA--YIESQGAH-RAGLAKVVPPKEWKPR----ASYDDID--DLVIPAPIQQLV---
-TGQSGL-----------------------------FTQYNI------------------
--QKKAMTVRE---------FRKI--------------------------ANSDKYCTP-
------------------------------------------------------R-YSEF
------------------------------------------------------EE----
------------------------------------------------------------
-------------LERKYWKNLTFNPP-I---YGADV----NGTL-----YEK-------
------------------------------H-VDEWNIGRLK----TILDLVEKESGITI
EGVNTPYLYFGMWKTSFAWHTEDMDLYSINYLHFGEPKSWYSVPPEHGKRLERLAK---G
FFPGSAQSCEAFLRHKMTLISPLMLK-KYGIPFDK-------------VTQEAGEFMITF
P--------------------YGYHAGFNHGFNCAESTNFATRRWIEYG---KQAVLCSC
RKDMVKISMDVFVRKFQPERYKLWKAGKDSTVIDHTLPTPEAAEFLKESELAP-------
-------------------------------------RARNEECPEEDDMEGLEDGEEGD
FKRSLAKHRIGTKRHRVCLEIPQEVSQSELFPKEELSTGQYDMTECQAALAPVRPTHSSV
RQVEDNLPFP-DYSDSSEVKFEEL-----------KNVKLEEEDEEEEEEQEAAALDLSV
NPASIGGRLVLSGSKKKSSSSLGSSSSRDSISSDSETSEPLSCRAQGQSGVLTVHSYAKG
DGRVVMGEPCTRKKGGATGSISERELAEVADEYMF---------------SLEENKKSKG
RRQPLSKLPRHHPLVL--QDCVSDDESSEQLTPEEEAE--ETEAWAKPLSQLWQNRPPNF
EAEKEFNETMAQQAPHCAVCMIFQTYHQVEFGGLSQSCG------N--TSALAPQKQRTK
PLIPEMCFTSTGC----------STDINLST------------------------PYLEE
DGTS-------------------LLVSCKKCSV-----------RVH-------ASCYGV
PPTKASED--WMCSRCS----ANALEEDCCLCSLRGGAL---QRANDDRWVHVSC-----
-AV-AIL--------EARFVNIA---ERSPVDVSKIPLPRF---------------KLKC
VFCK-KRRKRTAGCCVQCSHGRC------PTAFHVSCAQAAGVMMQPDDWPFVVFITC-F
RHKIPNLEMAEQKPAKVAEKVQMEATGGGSGASIFFQRAKGALQSITA-----GQKV-IS
K---HKNGRFYQCEVVRLTTETFYEVNFD-DGSFSDNLYPEDIVSQDCLQLGPPAEGE--
-VVQVRWTDGQVYGAKFVASHPIQMYQVEFEDGSQLVVKRDDVYTLDEELP--KRVKSRL
SVAS------DMRFNEI--FTEKEVKQ-EKKRQR-----VINSRYRE------DYIEPAL
------------------------------------------------------------
----------------------------YRAIME-----------------
>gi|37360130|dbj|BAC98043.1|	Mus musculus
------------------------------------------------------------
---------------------------------------------------------LHF
AATMGSEDHSA---QNPS-------------------------CKIMTFRPTMDEFRDFN
RY-VA--YIESQGAH-RAGLAKIIPPKEWKPR----QTYDDID--DVVIPAPIQQVV---
-TGQSGL-----------------------------FTQYNI------------------
--QKKAMTVGE---------YRRL--------------------------ANSEKYCTP-
------------------------------------------------------R-HQDF
------------------------------------------------------DD----
------------------------------------------------------------
-------------LERKYWKNLTFVSP-I---YGADI----SGSL-----YDD-------
------------------------------D-VAQWNIGNLR----TILDMVERECGTII
EGVNTPYLYFGMWKTTFAWHTEDMDLYSINYLHFGEPKSWYAIPPEHGKRLERLAI---G
FFPGSSQGCDAFLRHKMTLISPIILK-KYGIPFSR-------------ITQEAGEFMITF
P--------------------YGYHAGFNHGFNCAESTNFATLRWIDYG---KVATQCTC
RKDMVKISMDVFVRILQPERYEQWKQGRDLTVLDHTRPTALSSPELSSWSASRTSIKAKL
LRRQISVKESRPWRKAEEER------RREPTRRPGPASHRRRSQPKKSKPEESRSPGEAT
AGVSTLDEARGCSRGEAMPE----DEEEEELLPSQGHEAEGVEEDGRGKPRPTKARNKKK
TPSPSSPPLL----SAPPALFPTE-----------EVLRPPPQPKSPGPAMGPMAAEGGP
PPTPLN----VVPPGAPVEEAEV--RPRPI--IPMLYVLPRTSSTDGDREHSAHAQ---L
APMELGPEEENQAQAGDSQ-------------------------------LKVEIKKSRR
--HPLGRPPTRSPLSVVKQEASSDEEAFLFSGEDDVTD---PEALRSLLSLQWKNKAASF
QAERKFNAAAALSEPYCAICTLFYPYSQSVQTERDS---------A--VQPPSKSGQRTR
PLIPEMCFTSSGE----------NTEPLPAN------------------------SYVGE
DGTS-------------------PLISCAHCCL-----------QVH-------ASCYGV
RPELAKEG--WTCSRCA----AHAWTAECCLCNLRGGAL---QRTTEHRWIHVIC-----
-AI-AVP--------EVRFLNVI---ERNPVDVSAIPEQRW---------------KLKC
IYCR-KRMKRVSGACIQCSYEHC------STSFHVTCAHAAGVLMEPDDWPYVVSITC-L
KHRASG---------------------------AGGQLLR----TVSL-----GQIV-IT
K---NRNGLYYRCRVIGTTAQTFYEVN---------------------------------
-----------------------------FEDGSQLTVKRGDIFTLEEELP--KRVRSRL
SLST------GTPQEPS--FSGDDVKAAKRPRVA-----SVLATTTE------DTGRSPE
------------------------------------------------------------
----------------------------YLSFMESLLQAQ----GRPGAPF
