>gi|50307403|ref|XP_453680.1|	Kluyveromyces lactis
------------------------------------------------------------
--------------------------------------------------------MKVY
LRKSPRAIALVSNGYVLIFEKRQNSTSSFLKGGSPKVTVQSVLESAFDTEPYTQLNHTTF
TALFGLITVKGQVFIGIITSNKKVGSPRWKLNE----------QDKVIEEETIYQILNIN
FYCIDSDKYDSM----FQDLSDI--GYERQLTEHPCGHLKML-----ISDGSFYYSNDFD
ITNSLQERG-----LVHRIEYTIDNQDQRYVWNYNQISEIVQL----RSRIAVQERPYFD
SGSFLVFLVRGFCQTITDGISSSCTLISRISTEGMNNLSEF----KGIDQSGKVSNFVET
EIIVQTRRNVFSYTMTGGDIPLNWELVEGQFLHGKKPKLLSKA-------STVQPSFDLH
FDEL-----MSKYGVVSIVNV--------SKPKNDAYEAMINTYQKCASSKGIDLTLIED
STSAL--NRIPHRIIYL--------------LQQKIYEFGSFAYDMDKKIYVGKQTGVFR
ISAVNLFKKLNIVEKVISADVLELTINELEEKDISSDFWKSHDSLWKSNDFWLERLNSKH
SKNPSKYKKIYRGLFDPSAIVALYDPLHIYVT----------------------------
-----RFLRQR-----------RHEYTFEKEISIFAGTFNVNGKL---SKEK-LEGWLKP
ENESP-----------DLYVIGLEEIVELSPGHMLATDPYI--KTFWEKKLLSEINSYND
--KKYHAVFNSQLGGLALLVFTDEENKSRIKHIEGDMKKTGF---GGISSNKGAIAVHLW
LSNTKFCFVVSHLSAGLENVEQRHNDYKSIAKHIRFS---------------KGTRI-KD
HDGVIWMGDFNFRI--LL------SNDDVRQAIIDKNYHR-------LFEKDQLNQQMIS
GESFPFFDE-MEITFPPTYKFNPGTDV---YD----TSEKMRIPAWTDRIL--SR-----
G-----------------EILRQEL-YGSAEDIVFSDHRPVYGLFTAKL--TVIDEPKKA
KLVASIKDSINETLK------DLTEEEKLAYLEENDILASKEEYSSSNPATANEPKKNKK
LP-----------PPSSDQHK-------W-------------------------------
---------------------WVGNGK--Q-----AKVSL--------------------
-------------------QVNPKK---YIL---NPERS------SNPFQQSEL------
------------------------------------------------------------
------------------------------------------------------------
--------------------------------------------------------PVFM
ERGQLSESDLQNKME---------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
---
>gi|125818583|ref|XP_687502.2|	Danio rerio
------------------------------------------------------------
------------------------------------------------------------
----------------------MEELQRAASEGVPIRFFS----------ALPDLVDAYY
KENMGL-----------------ITHLQYAVQK-----------EEEPPEEEPEPLSLPP
QLPPRNI---------FSNDSKESHNDPSRGTDRGTEPSRPS-----ISDTYFQRLQQID
ISNLPEDHQ----------------------------KSIQEYFRASVCLDAEQVQNGNQ
TLPHFKKLTQNICKNLNSEIARTL---------------------PSFEALQKVLDQPLS
PGAGRLRTQLSADANPSVAFRLEQLTKLIQSIEDKTKNAVFEFVGYDGGHRNSLIPPVTF
EVKS-DSLGISNKMYLKVDVEGGKVYFKKSKDGPEDKYFVHNKILQLVKSQKMHNRLVLV
VETE---KGKTQSKDFV-------------------------------FDDTKKREGFCQ
LL----------------------------------------------------------
------------------------------------------------------------
-----QQMKNK-----------HSGKPEPDMITIFVGTWNMGNAN---PPQN-ITSWFQS
KGQGKTHDDTANQIPHDIYVIGTQED-PLG-------------EKEWIETIRGALRDITN
--ISFKQIATQTLWSIRIVVLAKPEHENRFSHIFSDSVKTGI---ANALGNKGAVGVSFM
FNRTSFGFVNSHLTSGSEKKLRRNQNYVSILRFLNLG-----------DKKVNPFDITHR
FTHLFWLGDLNYRV--DLPS---HEAENIVMKIKQQQYKE-------LLAQDQLKIEKDE
EKVFLEYVE-EEITFAPTYRFERDTRERYAYTKAKATGTKYNLPSWCDRVL--RKSY--P
L-----------------VHVVCNS-YGCTNDIMTSDHSPVFATFDVGVTSQFVSKNDLS
N-DARGAIKILNCVA------VLCTKSKTKFFIEYHSSCLEKFV-RSPDGENQEME--GS
IKVRFGE-MTLQLTPIIADPEYLLDQHILICIKSTDSDESYGEGC---VALRSAESSYTE
FSIKLTHHGERTGWLTGAIQLPKSEGK--QTEKLYDFIKVGDDPGAGKGKTGENTKMSSS
VLATDISNPSYMGVGYKSGIQAPGS---LTS------QR------TGPSKDMT-------
-----------HGNISPKKTSYDHATSSPTA-----------------KTSNPIPVDGQP
PEMFDNPLYGSMSGSRGAKE--HHPPPDALFAFPKPT-----------------------
DFDSDRQPPVPTPRLRSYTCSETKPQS-----------------------------SSST
NLNMSSLLPQSITKKPVVPSRSEGGMIGPNRPPVPMKSRSGQTQEPQTKPRDYRDSSELP
SKIRPPT---------------------------RAGQTKDVHSETPPLKMGRQLK----
------------------------------------------------------------
---
>gi|68483026|ref|XP_714547.1|	Candida albicans
------------------------------------------------------------
--------------------------------------------MRLYLIEKPRTFVITT
NTHALIIRHPSPTYKHSGIKGLVSGHSKDKDQNKDTKVLVEFVLKEYLDLSLYRDITPKH
GGLLGL------------LGLLNVKGKTFIGFI-----TRDEWTASATVTDRIYKITDTE
FYCINNDEYDYL----LDKEYENMSHQERERLRYPAASVQRL-----LSSGAFYYSKQFD
MTSNIQERG---FVSSDYKLIADSSFFKSFMWNGFMTEELIET----RKRMSPAEQKIID
KSGLLIIVIRGYAKTVNTTVGGCEALMTLISKQSCAKEGPLFGD-WGSDGDGYVSNYLES
EIIIYTEKFCLSYVIVRGNVPMYWELENNFSTKTI-LAANGKQIAFPRSFEASQEALVRH
FDRL-----SSQYGDIHVLNT--------LSDKSYKGVLNSAYEEQLKYFLQNRESTDIG
YKVLYTRIPIASSRIKKIGYSGQNPYDIVSLLSNSIIDFGALFYDSKPNSFIGKQLGVFR
INSFDSLNKANFLSKIISQEVIDLAFRDI-GLELDRELYVKHAQLWEENDLWISKLTLNF
ASTSDKLHTSHNSIKSSFVKSHITKKYFGGVVESKPNEIAMLKLLGRLQDQSPVTMFNPI
HNYVNKELNKR-----------AKDFTSKLDLSVYASTFNVNGSV---YEGD-IDKWIYP
EENDY-----------DLIFIGLQEIVVLNAGQMVNTDFRN--KTQWERKILGVLQKR--
--NKYMVMWSGQLGGVALYFFVKESQVKYVSNVECSFKKTGL---GGVSANKGGIAVSFK
FSDTTICFVSAHLAAGLSNIEERHQNYKALIKGIQFS---------------KNRRI-QN
HDAVIWLGDFNYRI--DL------TNDQVKPMILQKLYAK-------IFECDQLNKQMAN
GESFPFFSE-QEINFPPTYKFDKGTKV---YD----TSEKQRIPAWTDRILFLSR-----
Q-----------------NLIEPLS-YNSCQNLTFSDHRPVYATFKITV--KIINHTI--
--KKNLSDEIYKNYK------------------DSHNGIFDILV-KSFDNKELNEGKDAS
LP-----------APSSDKHK-------W-------------------------------
---------------------WLEGGK--A-----AKIII--------------------
-----------------PGLEDD-N---M------VMNP------WRPINPFE-------
----------------------KSNEPEFVS-----------------KN----------
----------------------DLEAIQN-------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
---
>gi|47209984|emb|CAF94205.1|	Tetraodon nigroviridis
------------------------------------------------------------
------------------------------------------------------------
----------------------------------------------FQKHVHTYRILPDE
EGFLAV------------QTSQGVQPKRFKKLP----------ELVSLYLQPNQGLVTTL
LYAVDREETA------FTDERDY------SDGEDEKPPLPPR-----LASTSTPPASEAP
TDSAPATNG--------------------------LSTISHDYLKGSYALDLEAVKQGAC
SLPHLNKALVTSCKRLNGEVDKVL---------------------SGLEVLSKVFDQQ--
------------------------------------------------------------
------------------------------------------------------------
-------SAFMVSKMIQ------------------------------QSVNQGGDQEL--
------------------------------------------------------------
------------------------------------------------------------
-----ENLVTK-----------------LAILKDLLSSMEKKALK---ALQD-MSLSSSC
SPLLSSHHSKAIPVKLDVYLAELTKI-------------GK--SQKYTLSVDVEKGRL--
--VVMKKIAVQTLWNIKLAVLVKPEHENRISHVGMSSVKTGI---ANTLGNKGAVGVSFM
FNGTSFGFVNCHLTSGNEKITRRNQNYLDILRLLSLG-----------DKQLSSFDISLR
FTHLFWLGDLNYRL--DM------DIQEILNYINRKEFEP-------LLKVDQLNLEREK
NKVFLRFAE-EEILFPPTYRYERGSRDTYVWQKQKATGMRTNVPSWCDRIL--WKSY--P
E-----------------THIICNS-YGCTDDIVTSDHSPVFATFEVGVTSQFVSKKGLP
KCSEQAYIEFESIEA------IVKTASRTKFFIEFYSTCLEEFK-KSYDNDSQSSDNINF
LRVGWSNKQLTTLKPLLSEIEYLQDQHLLLTVKSVDGYESYGE-CVLALKSMIGSTPQQF
H-TYLSHRGEETGNIRGSMRVRVPSERIGTRERLYEWISVDKDETGGPKGKSAILSRVGH
EYI-------------KSGLVCK-QLSELGKLTEDVERISKEETSTRPKQDGSEGDLSMC
KNSYNNPAYYILEGVPNQSAAAISPELLQPPTSCSPSMAKAPPQSARSKSSYVTSGHCLR
RPMSGHPVCAINEEGSSEDDGGTQGGVESTLNRPPPDFPPPPLPKGALGMVIDP------
SFSKAQPTYPDLGDIRIPAAITSAPLAT----------------------------GESF
RRGGAGALDDQSC---SVLQMAKSLSES-EFQGQPPRASSAPPPSKGQPVSSGLDTTCSF
PPRHTIT--ESIAEDLPEEALWGSSSSSLSVGESSVGEWLQ-RLGLERYEQGLLHNGWDD
LEFLS-----------------------------DITEEDLEEAGVLDPSHKQILLESLK
---
>gi|45187872|ref|NP_984095.1|	Ashbya gossypii
------------------------------------------------------------
------------------------------------------------------MKLFVR
KEPRAIALASNDYVLVFERSKNNPKQPQVKNAPPTIMVKTMSEASLVNGGGFVEWTAFLI
KGLLGVIHVRNQVFIGLITGVKDVAKPRWRIRD-----------GKMKSIESIFQILSVN
FYCLDSPLYD------QWLYYVSEICQEKLLTEHPCAPLKKL-----FSDGTFYYSRDFD
ISNVLQERG-----LKHRIENTIENQEKKFIWNLNLMSEILQL----RGRITPAELQAFD
GGQFLTFLIRGFCKTVFANEIHSPTSLTLISKTSIEDLDSINDFQKGIDEEGNVARFIES
ELIIQTERYLFAYVQTSADIPLSWEVVEGQLLHSKKLKLTKSP-------ERIQATFDRH
FDDM-----ISRYGVISIVNL--------VKHRSSSQETLSGAYKACAEVKELHYTAVDY
PVDVI--KKSPYKLMYF--------------LRDDIYEFGAFAYDIARGVYVGKQTGSFR
VSAVDATSKMNLVEMCISREVLDLTTDELEDFAITTSLVKKHEALWSDNDFWLHRIHTKN
IKNPAKYKKVYSQVFSLSSKVLLYDPLHAHIA----------------------------
-----KCLKKL-----------KNEYTYEKEISIFAGTFNVNGKQ---CKDEAMGTWLFP
PNGESEGNYA------DIYVIGLEEVVELTPGHMLSTDPMS--KQFWEKTILRHLNSQEG
--RHYNCIGTNQLGGVLLLLYVNESECSKIKHLEYDVKKTGF---GGISANKGAAAIRFM
YSATKFCFIVSHLAAGLENVEQRHSDYKTIMKSIGFS---------------RGKRI-KD
HDGIIWMGDFNYRI--LL------SNEEVRRAILEGDYGK-------LFEKDQLNQQMIA
GESFPYFNE-MEITFPPTYKFDPGTKS---YD----TSEKMRIPAWTDRIL--NR-----
G-----------------EILKAIS-YGCAEDVIFSDHRPVYATFKART--TVVDEEQRG
QLSRIIHERLTEMFS------GLNDEQKYAFLVD-SELIVDKIEM------------EGK
LPLVSQVKKGKRLPPPSSDL---RK---W-------------------------------
---------------------WIGNGK--Q-----VRITL--------------------
-------------------DVDPKK---------QMLNP------ERPVNPFI-------
--------------------PGEDGQAYVVP-----------------KSRLNN------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
---
>gi|110761623|ref|XP_396184.3|	Apis mellifera
------------------------------------------------------------
------------------------------------------------------------
---------------MSSSEQSMIVQSKFVSGETAME-------------ASLIQGWVKA
ARIIAL---------------LNKGTTHALVIL----------ITSRTPPQVYSDLTIER
VLPIDQD---------FKCNINT--------DDKQQDSLDVY-----LNVTSRKLHLIFE
MRPGVVTIY--------------------------------------------QKTKNSA
SEFLWIQKLTGNTRNLNSNTNEEV------------------------------------
------------------------------------------------------------
QDNT-----DP------------------LVDLESPV-----------------------
-------LVVTRRSIAS------------------------------GKSPVAARESAVR
------------------------------------------------------------
------------------------------------------------------------
-----YQMACK-----------EDDYTYSKTFRIFIGTWNVNGQP---PNGIKLHRWLSY
DKTPP-----------DVYAIGFQEL-DLTKEAFLFNDTPR--EEEWRQVVAKSLHPN--
--GIYEQVAIVRLVGMMLLIYALHNHVPYIKDVSVDTVGTGI---MGKMGNKGGVAVSCS
IHNTSICFVNAHLAAHCEEYERRNQDYADICARLSFT------------KYVPPKNF-KD
HDQIYWLGDLNYRI--TEM-----DVMVAKQYIDEENYSA-------VLVLDQLGQQRRL
GRVLQGFQE-AEITFKPTYKYDPGTDN---WD----SSEKGRAPAWCDRIL--WK-----
G-----------------EAITSID-YRSHTELKISDHKPVSAIFDSQI--RIIDMAK--
--YRKIHEEVMKKLD------KLENEFLPQVMVDTTEIIFDTLKFLEPSSKELIIANTGQ
VPVQFEF------IKKLGDTSYCKE---WLDIEPFKGFIKPGEKCDTRFEIYVDKRSACK
L-------NSGEDKLYDILILHLEGGK--D-----IFITV--------------------
-----------------TGTYERSC---FGSSMEALVHI------PVPIREIPIGRLMEL
ENN-----------------KNLSQEPYAIP-----------------KEIWLLVDRLYR
HGIKTTGLF----ETPGLPS--EIIAIRDWLDNWSQD-----------------------
PMP--GSVHSVAEALLL--LLESTAEPL----------------------IP----YNLH
SVCLSA----------IVMQLPEIRRTVFVYICYFLQELLNHTQDNELDAKTLATIFGSI
FLRDPPR---------------SRGDKNQRSRTQVVQATID-RKKA-AFVYHFLINDQSD
FILGR-------------------------------------------------------
---
>gi|109511192|ref|XP_229106.4|	Rattus norvegicus
MCPFVLLQYDTRQTLKSSKKFSERYKEALLHRNWSIPFQPSSNERRASKQTALLRGRNLR
RPGRRAGAGGAALSRVRLSPPGSPAPRLAPRLPGSRAPRLPAPSGAGALPLRLGKAGGRA
AGRRRRCRGIRWQSAAPQSLEAALMEPRLPIGAQPLAMVA----------GLEMKGPLRE
PCVLTL----------------ARRNGQYELII----------QLH------GKEQHVQD
IIPINSH---------FRCVQEA--EETLLIDIASNSGCKIR-----VQGD-WTRERHFE
IPDEERCLK--------------------------FLSEVLAA----QEAQSQLLVPEQK
DSSNWYQKLDTKDKPAYSGL-------------------------LGFEDN---------
-----------------------FSSMNLDKKMNTQNPPTGIH---------REPPPPPS
SNRM-----LPR------EKE--------ALNKEQPK-----------------------
-------VTNTMRKLFA------------------------------PNSQSGQREGLIK
------------------------------------------------------------
------------------------------------------------------------
-----HILAKR-----------EKEYVNIQSFRFFVGTWNVNGQS---PDSS-LEPWLNC
DPNPP-----------DIYCIGFQEL-DLSTEAFFYFESVK--EQEWAMAVERGLPSK--
--AKYKKVQLVRLVGMMLLVFAKKDQCQYIRDIATETVGTGI---MGKMGNKGGVAMRFV
FHNTTFCIVNSHLAAHVEEFERRNQDYKDICARMSFS---------VPNQTLPQVNI-MK
HDVVIWLGDLNYRL--CMP-----DANEVKSLINKNELQK-------LLKFDQLNIQRTQ
KKAFVDFNE-GEIKFIPTYKYDSKTDR---WD----SSGKCRVPAWCDRIL--WR-----
G-----------------INVNQLH-YRSHMELKTSDHKPVSALFHIGV--KVVDERR--
--YRKVFEDIVRIMD------RMENDFLPSLDLSRREFMFENVKFRQLQKEKFQISNNGQ
VPCHFSF------IPKLNDTQYCKP---WLRAEPFEGYLEPNETIDISLDVYVSKDSVTI
L-------NSGEDKIEDILVLHLDRGK--D-----YFLTI--------------------
-----------------SGNYLPSC---FGTSLEALCRM------KRPIREVPVTKLIDL
EEDSFLEKEKSLLQMVPLD-EGTSERPLQVP-----------------KEIWLLVDHLFK
YACHQEDLF----QTPGMQE--ELQQIIDCLDTSIPE-----------------------
TIP--GSNHSVAEALLI--FLEALPEPV----------------------IC----YELY
QRCLDSAHDPRICKQ-VISQLPRCHRNVFRYLMAFLRELLKFSDYNNVSTNMIATLFTSL
LLRPPPN---------------LMAR----------QTPSD-RQRAIQFLLVFLLGSEED
------------------------------------------------------------
---
>gi|108881371|gb|EAT45596.1|	Aedes aegypti
------------------------------------------------------------
------------------------------------------------------------
-----------MSSGSHDSAIIAAVTRKFRTGESVLAIFE----------VYQILGSKHQ
NQLLVI----------------VSSNCTSALFA---------FSISRYPPETISDLTVVA
VYAIDDS---------FWINPES-----GGHGSISSHQCTVF-----SHDE-PTVYYYQG
TPDAIVSRD-------------------------NFISKLKSLISTYKSASSQAATVSIS
LDFTWLDYYKRAD-----------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-------MLAIDRSIAE------------------------------GSQAPKSRDSKFK
------------------------------------------------------------
------------------------------------------------------------
-----EELERR-----------RHEYIVYEPYKIYTATWNVNGQT---SENIELPEWLST
TEDPP-----------DIYAVGFQEI-EWTPEKIIMNETKI--DRTWVDKVMSGLHNG--
--AEYEEVASVRLVGMMLTVAVKKSLRDRISDCLTAAVGTGT-------LKWGGVGVSFQ
MNEALFCFVNTHLAAHTQEVERRNEDHDEIIRRMSFE------------KTFRGRSI-DE
HHHIFWIGDLNYRL--SG------DVSQEAVNLKDGDYNQ-------LYPFDQLYVEKLR
KRIFRGYNE-GKILFCPTYKYNPGTDD---WD----SSEKSRCPAWCDRVL--WK-----
G-----------------QRMELLK-YDSVMQLRRSDHKPVYAVFNVDV--ETKDDHK--
--FKRVHEEVLKTVD------KYENDNQPQITVEQTDLDFGLIRFNERYSRELLVANNCH
LPVQFNF-----SAKDDRNSSVCEE---FIHISKKSGELLTGDSRSIRIDIFIDAKAASK
MLKKLKDAKAGVKIPLDILVLHVKNGR--D-----IFITI--------------------
-----------------FGEYKSSC---FGLSLDTLIKL------TKPVFEYEINELIAM
ERE---------EKLVDLN----NGTDLKVP-----------------REIWRLIDYLYT
EGMDTHQLF--VNRAYGQHE--NIVEIRDWLDSWSSA-----------------------
PCP--ATPKTAAEALLI--FLESLPEPL----------------------V-----TISE
RECIVNADNYERCRELIRVKLKPVNRIIFLHICLFLIEL--QRKNPSVRLNNLATTFGRI
LIRSQLT---------------PGRTPTGNDVYA--YTEGE-RDQRRRFMMTFLTNNNGV
QEFAR-----------------------------AEMNGTGT------------------
---
>gi|109107815|ref|XP_001114749.	Macaca mulatta
------------------------------------------------------------
------------------------------------------------------------
------------------MVTRLLQQQNLPQTGEQELE------------SLVLKLSVLK
DFLSGI-----------------QKKALKALQD----------MSSTAPPAPQPSTRKAK
TIPVQA----------FEVKLDVTLGDLTKIGKSQKFTLSVD-----VEGGRLVLLRRQR
DSQEDWTTF--------------------------------------THDRIRQLIKSQR
VQNKLGVVFEKE------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-------KDRTQRKDFI-------------------------------FVSARKREAFCQ
LL----------------------------------------------------------
------------------------------------------------------------
-----QLMKNK-----------HSKQDEPDMISIFIGTWNMGSVP---PPKN-VTSWFTS
RGLGKTLDEVTVTIPHDIYVFGTQEN-SVG-------------DREWLDLLRGGLKELTD
--LDYRPIAMQSLWNIKVAVLVKPEHENRISHVSTSSVKTGI---ANTLGNKGAVGVSFM
FNGTSFGFVNCHLTSGNEKTARRNQNYLDILRLLSLG-----------DRQLSAFDISLR
FTHLFWFGDLNYRL--DM------DIQEILNYISRKEFEP-------LLRVDQLNLEREK
HKVFLRFSE-EEISFPPTYRYERGSRDTYAWHKQKPTGVRTNVPSWCDRIL--WKSY--P
E-----------------THIICNS-YGCTDDIVTSDHSPVFGTFEVGVTSQFISKKGLS
KTSDQAYIEFESIEA------IVKTASRTKFFIEFYSTCLEEYK-KSFENDAQSSDNINF
LKVQWSSRQLPTLKPILADIEYLQDQHLLLTVKSMDGYESYGE-CVVALKSMIGSTAQQF
L-TFLSHRGEETGNIRGSMKVRVPTERLGTRERLYEWISIDKDEAGA-KSKAPSVSR-GI
QEP-------------RSGSRKP-A---FTEASCPLSRL------FEEPEKPPPTGRPPA
PPRAAPREEPLTPRLKPEGTPEPEGVAAPPP-----------------KNSFNNPAYYVL
EGVPHQLLPPEP-PSPARAPVPPATKNKVAITVPAPQLGRHRPPRVGEGSSSDEESGGTL
PPPDFPPPPLPDSAIFLSPSLDPLPGPVVRGRGGGEARGPPPPKAHPRPPLPPGPSPAST
FLGEVAGGDDRSC---SVLQMAKTLSEVDYAPAGPARSALLPGPLELQPHRGLSSDYGRP
LSFPPPRIRESIQEDLAEEAPCPQGGRASGLGEAGMGAWLR-AIGLERYEEGLVHNGWDD
LEFLRWRRGWPRGRSWGPQDPLAHLTSQAVLLHSDITEEDLEEAGVQDPAHKRLLLDTLQ
LSK
>gi|50290731|ref|XP_447798.1|	Candida glabrata
------------------------------------------------------------
---------------------------------------------MRIFVGRNPRSVVLS
SESYSLKFERLYDRSNQTQGNVQAQQGQPNQIKAPTVSIKNVSASELVKDGYRELRALRL
NGLLGLLTINGDVYVVVVGGVQSIGYPRWHLDD----------SSKITPEQSINKILEVD
FISLDTEIYDHL----FFDRSEQ--NFDKLLHEHPCGVYKRL-----FADGSFYYTKDYD
LTNAVKSPG-----LTHNLDYAIDNFDTSFIWNANLIGEIINW----RGRLSMKEKQAFD
NAPFLMFVIRGFCKTSIVNDPDLTATVTVLSRVSTEGHKSISDS-EGMHEDSRVSTIIET
ETIVTTDSFILSYTQIAGNIPLFYEIIDGQLLSGKKLKLLKQP-------GEGQNEFNKH
FDTL-----ESKFGIVSVVNL--------VKSRSDSQETLASIYKQYSDTRGIKISNIPC
GSQTL--NKSPHKVLYS--------------LKQDIYECGAFAYNIKKGIYFGKQTGVIR
ISAADPIEKPILLEKLISKEVLELATKELDGFSITSPLLEVHDKLWSENHFWLERVYAKN
QKNYNKSAKIYLKLFSSHVKLFDPVHFYIS------------------------------
-----QYLRQF-----------RSSFTHMKDIKVFAGTFNVSGKL---SKDD-ISQWIFP
NGVTTEEDFA------DVYVFGLEEVVELTPGHMLAIDPYI--KQFWEKKLLDTINYYDK
D-SSYTKVWSSQLGGVLLILLMKSSESLKVKHVEGDVKKTGF---GGITSNKGAVAVSFN
YSATRFCVLVSHLAAGLENVEQRHNDYKMISKNIRFS---------------RGLRI-KD
HDAIIWMGDFNYRI--LM------SNEEVRKLIALKDYKS-------LFEKDQLNQQMIA
GESFPYFHE-MPIEFPPTYKFDPGTRQ---YD----TSEKLRIPAWTDRIL--GR-----
G-----------------DVLRQLT-YTYAPDVLFSDHRPVSAVFSANV--TVVDEKKKA
ELSSVIHTKLMERLE------GCDEDERIEILND------GNFKLNELDDEISNITNMNA
KPEQKRARK---LPPPSSEI---RK---W-------------------------------
---------------------WVGNGK--Q-------VKV--------------------
-----------------FLDTDPEE---FMLNPEHT---------PNPF-----------
--------------------DSNDTSPLFVP-----------------RS----------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
---
>gi|150865111|ref|XP_001384196.	Pichia stipitis
------------------------------------------------------------
----------------------------------MKLYLNERPRTFLVISNSYALIIRHP
RPKYRSSGLASHLHIHNGANKKDPSGANFSNKVLVEFVRKDDLDLSQFKDITPSKTKSRK
QILAFI-------------GLLNMKSNIYLGFI-----TSEETIASPTIGEKVSQIKTVD
FYCLNNDEYDHLLNRQFDEEPDQSQERDKLRSESPASSVRKL-----LSSGSFYYSRNFD
ICSNIQERGIPDTANPKFSLMADSPYFKRFMWNSFMNAELIEF----RNRLSLFEQQQFD
SSGFLITMIRGYAKTVNATVNNEDALLTLISKQSCIKNGPLFGD-WGCDDDGAVSNFVET
EVVIYTAKYCLAYVIVRGNVPIYWELDNYFSKKNILPNKNNRKIVYSRSFEASQHAFTRH
FDRL-----ANQYGEVHVLSALSTDKTTYKGDLNQAFEEHIESFNSTAPDLDNGAYNALS
YNLEYTRVPLTVSMMKKLGYGAQNPHDIVALLVESIVDYGALFFDLSKKTYTGKQLGVFR
VNSFDSLRKANYISKIISQEVIELAFRDI-GSTIDLDLYIKHAKLWSENEDILSKLTLNF
VSTSSKLQSSSATSTKSTVKSHLTKKYLSGVVDTKPNEMAILKLLGRLQDQVSITLHNPI
HDYVARELTKR-----------TKEYSSYKNISVFSSTFNVNGTF---NDGD-INKWLFP
SDADVDKAY-------DLVFIGMQEIVELNASQMVNINVGN--KFMWERKIKQVLDTSNA
KGLKYVSLWSGQIGGIALFLFIREDEIKSISNVEGSFKKTGL---GGMTANKGGVAVSFN
YSNTDLCFVCSHFAAGMSNIEERHHNYKTLIKGMLFS---------------KNRKI-RN
HDGVIWLGDFNFRI--GL------PNDQVKPLIEQRQFTK-------LFEYDQLNRQMAN
GESFPFFDE-MEIKFAPTYKFDNGTTT---YD----TSEKQRIPAWTDRILNMSR-----
E-----------------KIIKQLY-YNSCEDVIFSDHRPVSAVFKIKV--HIVNQTI--
--KKNLANEL-----------------------------YDSYRKNIGDINDILSNNSNV
MKF---FEEDKVLPPPSSEI---QK---WWL-----------------------------
------------------------EGK--P-----AKINI--------------------
------------------SELNNEQ---VEDGDVNVINP------KLPSNPFE-------
------------------------------------------------------------
-------------------------------ESTEPE-----------------------
------------------------------------------------------------
----------------------------FIHKSELLKLLSKA------------------
------------------------------------------------------------
------------------------------------------------------------
---
>gi|157016841|gb|EAL40350.3|	Anopheles gambiae
------------------------------------------------------------
------------------------------------------------------------
-----------MNCSNHDSIIIRTVTQKFREGESVLAILA----------AYQIVGNNFQ
NRLLVT----------------VSSSESAALFS---------FSVSREPPESISDLTILA
VVPINES---------FFVNTES------SFGSVSSHQFTVF-----SDNQPTTYYYHAT
EEISAAKEH--------------------------FLTSLKNL-----KASYRAVPVHSP
GAFDWLHYYKPADERTS-------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-------LLAIDRSVAD------------------------------GSQAPKTRDAKFR
------------------------------------------------------------
------------------------------------------------------------
-----EELERR-----------RHEYTVYEPYHVYTATWNVNGQT---SETIELPEWLAT
TDSPP-----------DIYAVGFQEI-EWTPEKILMNETKI--DRTWVDKVMSGLHKG--
--AIYTELASVRLVGMMLTVAVKSTIYPKINDCLTAAVGTGT---LK-WGNKGGVGVSFK
LNEALFCFVNTHLAAHTQEVERRNDDHDDIIRRMSFD------------NGFRMRSI-DE
HHHIFWIGDLNYRL--DGP-----EVSQEYVNRKDRDYNQ-------LYQHDQLYVEKRR
NRIFRDYKE-GKILFPPTYKYNPGTDE---WD----SSEKSRTPAWCDRIL--WK-----
G-----------------QRIEMLR-YNSVMQLRKSDHKPVYADFKVDA--QAKDQAK--
--LKKVSEEVLKTVD------KYENDNQPQITVEQTDLDFGLIRFNEKYSRELLVANNCH
LPVRFRF-----ACKDDRNSQVCED---FIHISHSKGELLTGNSLSIRIDILVNAPAASK
MLRKLKDAQAGSKVPLDILVLHVENGR--D-----IFITI--------------------
-----------------FGEYKPSC---FGVSLDTLMKL------NKPVSMYAIHELVSL
DHE---------EKLIDLVGDNVGGSNLRFP-----------------REIWRLVDNLRK
MGLQTPQLF-TLDRKLGQSDAANLLEIRDWLDSWSTD-----------------------
DFP--GTPHTTAEALLM--MLEALPEPV----------------------V-----TISE
RECIIASDNFERCKELLRTKLNSVNRILFLYICLFLQDF--WNANKSIRIDTIAGLFGRI
LIRSQL----------------PAKPEFSNSIYA--YSEGE-RDQRRRFMMTLLNNN--V
REFAR-----------------------------QEMSTL--------------------
---
>gi|126342340|ref|XP_001373660.	Monodelphis domestica
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
---------------------------MWLIIQ-----------------YYEKEMPTQD
VIPINSH---------FKCIQEA--AETLLIDIAANTPCKIR-----IQGD-CIGERLFE
IPDEDQCLA--------------------------FLTDILAA----QDAHKTASVPEFR
ESTSWYQKLDVSEKTPSETDVSGV---------------------LGFEDN---------
-----------------------FTEMSLEKKRNIHNKQMRTR--------REPPPPPSQ
TSKS-----FLR------EKE--------GGGRDQPK-----------------------
-------VSSTMRKLFV------------------------------PTSQSGQREGLIR
------------------------------------------------------------
------------------------------------------------------------
-----HILAKR-----------EKEYVNLQTFRFFIGTWNVNGQS---PDSA-LEPWLNC
DTDPP-----------DIYCLGFQEL-DLSTEAFFYFESTK--EQEWLTSVDRALHYK--
--CKYKKVQLVRLVGMMLLIFAKKDQCKYLHDVVTETVGTGL---MGKMGNKGAVAVRFL
FHNTTFCIVNSHLAAHVEDFERRNQDYKDICSRMTFS-----------VPNQGHLNI-MK
HDVVIWLGDLNYRL--CMP-----DANEVKTLINRNELPK-------LLKLDQLNIQRSH
KKAFADFTE-GEIRFMPTYKFDPKTDR---WD----SSGKCRTPAWCDRIL--WR-----
G-----------------TNVNQQR-YWSHMELKTSDHKPVSSLFLIGV--KVVDDRR--
--YRKVFEDSVRIMD------RMENDFLPSLELSKREFVFEKVKFRQLQKQKFQVTNNGQ
VPCHFSF------IPKLSDSQYCKP---WLRAEPCEGYLEPNEMVDISLDVYVSKDSVTL
L-------NSGEDKIEDILVLHLDRGK--D-----YFLTI--------------------
-----------------SGSYLPSC---FGTSLEALCRM------KRPIREVPVTKLIDL
GEDSFVEKESPLLPLAPVE-GNASERPLQIP-----------------KEIWLLVDHLYK
NGCQQEDLF----QTPGMQE--ELQQIIDCLDTSIPE-----------------------
TIP--GSNHSVAEALLI--FLEALPEPV----------------------IC----YELY
QRCLDYSHDPCLARQ-VVSHLPRCHRSVFRYLMSFLRELLKHSKANNVNVNMIANLFSGL
LLRPSPN---------------LMSR----------QTAND-RQHAIQFLLGFLLSGDED
------------------------------------------------------------
---
>gi|91090171|ref|XP_972767.1|	Tribolium castaneum
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-----------------------------------------------------MTDQSSD
IPVLRHQLA---------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-----------------------------------------------QGQAASNRESILR
------------------------------------------------------------
------------------------------------------------------------
-----YQLKLK-----------EPEYTQQQEFSIFVGTWNVNGQP---PSVS-LRPWLSF
DEEPP-----------DLYAIGLQEI-DLSKEAFLFNDTPR--EAEWVKYVMDGVHSK--
--AKYKSVAVTRLVGMQLIVLVNSKHYQFVKNVAVDTVGTGL---LGKMGNKGGVAVRLE
LHNTSLCFVNCHLAAHIEEFERRNQDYKDINARINFR--------------KQPQSI-KD
HEQVYWLGDLNYRI--TDL-----NTQQVKTLLARNEIVT-------LLKADQLNQQKDR
GHVLLDYTE-GDITFHPTYKYDLNTDT---FD----TSEKARPPAWTDRIL--WR-----
G-----------------EGIYQTA-YRSHMDVRISDHKPVSALFKSEI--SVIDQNK--
--FRRVHEDLLKKMD------KLENEFLPQVMVDQTEVVFDLVKFREPQAREIIIANTGQ
VPAEFEF------IKKLDEATYCKD---WLRITPFCGTIDPGDKCDIKFEVNLEREM---
------------DKVYDILVLHLKGGK--D-----MFIIV--------------------
-----------------TGECQRSC---FTSSISTLCRA------PVPLLQMS-------
------------EEQRKQAENMESRVLYSIP-----------------RELWHLVDNLYR
YGLKTRDLF----ESCALHE--EIIRIRDWLDYGSVD-----------------------
SLP--GTVQAVAEALLL--FLSYTKDPI----------------------VP----FELH
DSCIAAANNFQNCRLIIQQKMSDVHRNVFLYICMFLKELLKYSNENGYDAKTLASLFGDI
LLRDPIR----------------------------NSKPQA-NRGKANFVYNFLVNDLSS
SIIPN-----------------------------K-------------------------
---
>gi|125978663|ref|XP_001353364.	Drosophila pseudoobscura
------------------------------------------------------------
------------------------------------------------------------
-----------------MQHSTAGSEERITSSTSSPRSGHKTGSSLF---GLLTKRPSKV
EPHPVTPD------SPSLQRRPLSACGHYDVSFAKASAEQAGNHVAVSSSNNSNSNHKSQ
TLPLEKSHSGLIS---FHRRTKPPSKSKGHAHRYSSDAGSQS-----DGGADVVMRRKSP
KHRSPNHNR--------------------------FSHQFSLC-------CKAEKKPLTP
PVTVRYNSIPDSTSNSVLRRDNLSLS-------------------WSMVDNNSVSMNSSE
GGTSFQRPRLSSECASAPESPVGTKTFFAQCSKSESMPRSPIRPIAVSACRSRLRLKLYP
PGKE-----LPQLHTAEESTD--------IKRATTPQHMSSPNIASQPDGFEAAMQEQPG
V------RFMSHENMTL---------------------------QRQGSGSNLARQALVA
AHALNLIPAEKARER---------------------------------------------
------------------------------------------------------------
-----SYLDGRLGSSSLLGPSELSRVLPQKEVTIFVGTWNMNGHS---PPKQ-LNDFVLP
ANVEHVP---------DIVVMGTQES-TPD-------------RFEWEVTLQETLGPS--
----HVLFHSTTLGTLHLAVYMRRDLIWYCSAPEDASMSVRT---GSAFRTKGAVAISFC
LFGTSMLFVTSHLTAHQQKVKERVSDVKRIINALDLP-------RNLPNLRHKNKDVTQN
FDNVFWCGDLNFRL--GE------PREKLMEWIQNTKFPLPSHLPHGYMHTDQLSSVLAD
GAAFRGFME-ANITFPPTYKYDPGSQN---FD----TSSKQRAPAYTDRILYKYRQV--Q
GLVIRRQTIIPGVSTPTQPYVQCLL-YDSVPSITTSDHKPVWALFKTLI--RA-------
------------------------------------------------------------
------------------------------------------------------------
-------------------------GT--D-----AIPLA--------------------
-----------------AGLFSRDI---Y------LEGM------RRRLNN---------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
----QYTGASAVCAIQ--------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
---
>gi|114639232|ref|XP_001174654.	Pan troglodytes
------------------------------------------------------------
------------------------------------------------------------
------------------MVTRLLQQQNLPQTGEQELE------------SLVLKLSVLK
DFLSGI-----------------QKKALKALQD----------MSSTAPPAPQPSTRKAK
TIPVQA----------FEVKLDVTLGDLTKIGKSQKFTLSVD-----VEGGRLVLLRRQR
DSQEDWTTF--------------------------------------THDRIRQLIKSQR
VQNKLGVVFEKE------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-------KDRTQRKDFI-------------------------------FVSARKREAFCQ
LL----------------------------------------------------------
------------------------------------------------------------
-----QLMKNK-----------HSKQDEPDMISVFIGTWNMGSVP---PPKN-VTSWFTS
KGLGKTLDEVTVTIPHDIYVFGTQEN-SVG-------------DREWLDLLRGGLKELTD
--LDYRPIAMQSLWNIKVAVLVKPEHENRISHVSTSSVKTGI---ANTLGNKGAVGVSFM
FNGTSFGFVNCHLTSGNEKTARRNQNYLDILRLLSLG-----------DRQLNAFDISLR
FTHLFWFGDLNYRL--DM------DIQEILNYISRKEFEP-------LLRVDQLNLEREK
HKVFLRFSE-EEISFPPTYRYERGSRDTYAWHKQKPTGVRTNVPSWCDRIL--WKSY--P
E-----------------THIICNS-YGCTDDIVTSDHSPVFGTFEVGVTSQFISKKGLS
KTSDQAYIEFESIEA------IVKTASRTKFFIEFYSTCLEEYK-KSFENDAQSSDNINF
LKVQWSSRQLPTLKPILADIEYLQDQHLLLTVKSMDGYESYGE-CVVALKSMIGSTAQQF
L-TFLSHRGEETGNIRGSMKVRVPTERLGTRERLYEWISIDKDEAGA-KSKAPSVSR-GS
QEP-------------RSGSRKP-A---FTEASCPLSRL------FEEPEKPPPTGRPPA
PPRAAPREEPLTPRLKPEGAPEPEGVAAPPP-----------------KNSFNNPAYYVL
EGVPHQLLPPEP-PSPARAPVPSATKNKVAITVPAPQLGRHRHPRVGEGSSSDEESGGTL
PPPDFPPPPLPDSAIFLPPSLDPLPGPVVRGRGGGEARGPPPPKAHPRPPLPPGPSPAST
FLGEVASGDDRSC---SVLQMAKTLSEVDYAPAGPARSVLLPGPLELQPPRGLPSDYGRP
LSFPPPRIRESIQEDLAEEAPFLQGGRASGLGEAGMSAWLR-AIGLERYEEGLVHNGWDD
LEFLS-----------------------------DITEEDLEEAGVQDPAHKRLLLDTLQ
LSK
>gi|115529017|gb|AAI24574.1|	Xenopus tropicalis
------------------------------------------------------------
------------------------------------------------------------
----------AEPADEPGPGKRRAGKERYSMDRHKQVPSGGVT-------GHELKSGRKE
PCLLIL---------------SQLRDGQYALVI----------------HNQGRNSVSED
ILPITSN---------FKFVQEA--EETLLIDIPTNSGCKLR-----VQADPWSIERRFE
IQDEEKCMD--------------------------LLAEMKLV----QEGRVRHSRSEKK
ESSNWYQPANKTDDAGTSSKEPTEGT-------------------LGFEDN---------
-----------------------FSSVNLEKRRNIQNQQMGSR-------REPPPPPPAP
VERP-----LPPDR----ERD--------SSGWEKPR-----------------------
-------VTNSMRKLFT------------------------------PNTQSGQREGLIK
------------------------------------------------------------
------------------------------------------------------------
-----HILAKK-----------ENDYVNIKNFRFFVGTWNVNGQS---PDGG-LEPWLQA
DAEPP-----------DVYVIGFQEL-DLSTEAFFYFDSGK--EQEWLEAVERCLHTK--
--AKYKNVRLIRLVGMMMLVFAKHEHFKHIREVVAESVGTGI---MGKMGNKGGVAVRFV
FHNTSFCFVNSHLAAHVEDFERRNQDYKDICARLNFT---------VPDQNIPISNI-MK
HDVVIWLGDLNYRL--CKF-----DAAEVKSLIAKNDIQT-------LLKYDQLNIQREM
KNVFSDFTE-GTINFIPTYKFDAKTDR---WD----SSGKCRVPAWCDRVL--WR-----
G-----------------TNITQLK-YRSHMELKTSDHKPVSSLFSIGV--KVVDERR--
--YRKAFEDIVRMMD------RMENEFLPSLNLSRREFVFERVRFRQLQKEKFQIKNDGQ
VTCHFSF------IPKLNDTQYCKP---WLRAEPCEGYLEPEETVDISLEVYVSKDSVTM
L-------NSEEDKIEDILVLHLDRGK--D-----YFLTI--------------------
-----------------SGSYLVSC---FGTSLEALCRM------KRPIREIPVTKLIDL
GEDSFSEKEKAALQMLPLESDETADKPMKIP-----------------KEIWLLVDHLYK
NACRQEDLF----QTPGKQE--ELQQIIDCLDTSIPE-----------------------
TIP--GSNHSVAEALLI--FLEALPEPV----------------------IC----YELY
QRCIDCSHDTRLCRQ-VISQLPRCHRNVFRYLMAFLRELLKYTGDNNLSANMIATVFTSL
LLRPPPN---------------LIGK----------QTPSE-RQRAINFILGFLLSVDEE
------------------------------------------------------------
---
>gi|125981035|ref|XP_001354524.	Drosophila pseudoobscura
------------------------------------------------------------
------------------------------------------------------------
---MESVGDHVPNGLTGVKSNLEIVRERFKEDEIILYLFE----------AYQIKGPEDA
NRLLAL--------------VSSESGGTFAIIS---------FSFVRTPLTSVNELIVNK
VFAIDES---------FQLQQDC-------KGSITAYQFDLS-----TAEDGPIKYYFYP
SESASYEE---------------------------FVAKIISC-----KSSMARSDPETV
LNFRWLNDYR--------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------QIGEVK
------------------------------------------------------------
------------------------------------------------------------
-----QELKKR-----------ESEYIVYKDIIIYCATWNVNNKPCCDSPDG-LRSWLGC
SERAP-----------DIYAIGLQEL-DTPAKAMLNSTQVQASVAQWNEKMVQSVHPD--
--VEYEILQYHRLVGIMLTVIVRKQLRQHILRCRFKSVARGV---LNTLGNKGGVAISLQ
LNEGHICFVNSHLAAHMGYVEERNQDYNAIVDGLRFD---------------DGRTI-SD
HDHIFWLGDLNYRI--QEPP----GQQRPGPLTDAQTYEL-------LLQYDQLRQEMRK
GKCFEGYTE-GEIKFRPTYKYDPGTDN---YD----SSEKQRAPAYCDRVL--WK-----
G-----------------TRIEQLA-YNSIMDIRQSDHKPVYAVFRVKI--KTRDEVK--
--YKRVQEEVLKAVD------KRENDNQPQISVEKTVIDFGRVRFNEPCMQDFNVYNSCP
LPVDFSF-------KEKDIHDICEK---WLQVDPRKDSLMIDSARSIRIKMVADVHTIRG
L-----LKKIRTSDNFDILILHVENGR--D-----IFITV--------------------
-----------------TGDYQPSC---FGLSMETMCRT------DRPLSEYS-------
-----------QEQIKHLMNDDSQEYCVTMP-----------------REFFLLIDYLHK
QGSKLEGGFHTFEPRKSVNA--HFNVVRDWLDTWSDE-----------------------
EFP--GTPQSAAQALLL--LLDLPEQAL----------------------------LEPF
VEDLLACNSKSKAMD-YIALLSPPKRNVFMHLCMFLRE---GIECQYYELHQVAVTFGRI
LLRSSEC-----------------------------KAWPDYKVRCSQFMRLFIESDGAD
SLANR-----------------------------NEGAGAGS------------------
---
>gi|74008387|ref|XP_852376.1|	Canis familiaris
------------------------------------------------------------
------------------------------------------------------------
------------------------MEPPLSVGAQPLACLHTIE-------GMEMKGTLRE
PCALTL----------------AQRNGQYELII----------------QLHEKEQHVQE
VIPINSN---------FKCVQEA--EETLLIDIASNSGCKIR-----IQGD-RIRERCFE
IPDEEHCLK--------------------------FLSEVLAA----QEAQSQLLVPEQK
DSSSWYQKLDTKDKPVFSGL-------------------------LGFEDN---------
-----------------------FSSMNLDKKIISQNHPTAIH--------REPPPPPPS
VNRM-----LPR------DKE--------GSNKEQPK-----------------------
-------VTNTMRKLFV------------------------------PNTQAGQREGLIK
------------------------------------------------------------
------------------------------------------------------------
-----HILAKR-----------EKEYVNIQTFRFFVGTWNVNGQS---PDSE-LEPWLNC
DSNPP-----------DIYCIGFQEL-DLSTEAFFYFESVK--EQEWSMAVERSLHSK--
--AKYKKVQLVRLVGMMLLIFARKDQWRYIRDVATETVGTGI---MGKMGNKGGVAVRFV
FHNTTFCIVNSHLAAHVEDFERRNQDYKDICARMSFV---------VPNQTLPQLNI-MK
HDVVIWLGDLNYRL--CMP-----DANEVKSLINKNDLQR-------LLKFDQLNIQRTQ
KKAFVDFTE-GEIKFIPTYKYDSKTDR---WD----SSGKCRVPAWCDRIL--WR-----
G-----------------TNVNQLH-YRSHMELKTSDHKPVSALFHIGV--KVVDERR--
--YRKVFEDIVRIMD------RMENDFLPSLELSRREFVFENVKFRQLQKEKFQISNNGQ
VPCHFSF------IPKLNDSQYCKP---WLRAEPFEGYLEPNETVDISLDVYVSKDSVTI
L-------NSGEDKIEDILVLHLDRGK--D-----YFLTI--------------------
-----------------SGNYLPSC---FGTSLEALCRM------KRPIREVPVTKLIDL
EEDSFLEKEKSLLQMVPLD-EGASERPLQVP-----------------KEIWLLVDHLFK
YACHQEDLF----QTPGMQE--ELQQIIDCLDTSIPE-----------------------
TIP--GSNHSVAEALLI--FLEALPEPV----------------------IC----YELY
QRCLDSAQDPQNCRQ-VISQLPRCHKNVFHYLMAFLRELLKFSKYNNVSENMIATLFTSL
LLRPPPN---------------LMAR----------QTPSD-RQRAIQFLLGFLESDED-
------------------------------------------------------------
---
>gi|149413779|ref|XP_001517168.	Ornithorhynchus anatinus
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------LII----------------QSREKEMPAQD
IIPINSR---------FRCVQEA--EETLLIDIASNTGCKIR-----VQGD-FTGERLFE
IPDEERCLR--------------------------FLADVLAA----QEALLKPTIPDSK
DSSSWYQKLPPVDKPLNESTAPGI---------------------LGFEDN---------
-----------------------FTSLSLEKKRNLQNQQMGTR---------REPPPPPA
GNRV-----LPR------ERE--------ATSKEQPK-----------------------
-------VTNTMRKLFV------------------------------PNTQSGQREGLIK
------------------------------------------------------------
------------------------------------------------------------
-----HILAKR-----------EKEYVNIQNFRFFVGTWNVNGQS---PDSG-LEPWLNC
DPDPP-----------DIYCIGFQEL-DLSTEAFFYFESMK--EQEWLMAVEKGLHPR--
--AKYKKVQLVRLVGMMLLVFARKDQLSHIRDIAAETVGTGI---MGKMGNKGGVAVRFV
FHNTTFCIVNSHLAAHVEDFERRNQDYKDICARMSFL---------VPDQSLPQMNI-MK
HDVVIWLGDLNYRL--CIP-----DANEVKSLISRNDIQK-------LLTLDQLNIQRSH
KKAFADFIE-GDIKFIPTYKFDSKTDQ---WD----SSGKCRVPAWCDRIL--WR-----
G-----------------TNVQQQY-YRSHMELKTSDHKPVSSLFHIGV--KVVDDRR--
--YRKVFEDIVRIMD------RMENDFLPSLELSRREFVFEKVKFRQLQKEKFQITNNGQ
VPCHFSF------IPKLNDSQYCKP---WLRAEPCEGYLEPNETMDISLDVYVSKDSVTI
L-------NSGEDSIEDILVLHLDRGK--D-----YFLTI--------------------
-----------------SGNYLPSC---FGTSLEALCRM------RRPIRDIPVTKLIDL
EEDSFLEKDNTVCEMFPLENDDVSERPLQIP-----------------KEIWFLVDHLFK
NACHQEDLF----QTPGMQE--ELQQIIDCLDTSIPE-----------------------
TIP--GSNHSVAEALLI--FLEALPEPV----------------------IC----YELY
QRCLDYAHDTRLCRQ-VISQLPRCHRNVFRYLMAFLRELLKYSEDNNVSTNMIATLFTSL
LLRPPPN---------------LVTR----------QTQSD-RQRAIQFIMGFLLGGDEE
------------------------------------------------------------
---
>gi|55665969|emb|CAH69928.1|	Homo sapiens
------------------------------------------------------------
------------------------------------------------------------
------------------MDQSVAIQETLAEGEYCVIAVQ----------GVLCEGDSRQ
SRLLGL-----------VRYRLEHGGQEHALFL----------YTHRRMAITGDDVSLDQ
IVPVSRD---------FTLEEVS------PDGELYILGSDVT-----VQLDTAELSLVFQ
LPFGSQTRM--------------------------FLHEVARA---CPGFDSATRDPEFL
WLSRYRCAELELEMPTPRGCNSALVTWPGYATIGGGRYPSRKKR-WGLEEARPQGAGSVL
FWGGAMEKTGFRLMERAHGGGFVWGRSARDGRRDEELEEAGREMSAAAGSRERNTAGGSN
FDGL-----RPNGKGVPMDQS--------SRGQDKPESLQPRQNKSKSEITDMVRSST--
-------ITVSDKAHIL------------------------------SMQKFGLRDTIVK
------------------------------------------------------------
------------------------------------------------------------
-----SHLLQK-----------EEDYTYIQNFRFFAGTYNVNGQS---PKEC-LRLWLSN
GIQAP-----------DVYCVGFQEL-DLSKEAFFFHDTPK--EEEWFKAVSEGLHPD--
--AKYAKVKLIRLVGIMLLLYVKQEHAAYISEVEAETVGTGI---MGRMGNKGGVAIRFQ
FHNTSICVVNSHLAAHIEEYERRNQDYKDICSRMQFC---------QPDPSLPPLTI-SN
HDVILWLGDLNYRI--EEL-----DVEKVKKLIEEKDFQM-------LYAYDQLKIQVAA
KTVFEGFTE-GELTFQPTYKYDTGSDD---WD----TSEKCRAPAWCDRIL--WK-----
G-----------------KNITQLS-YQSHMALKTSDHKPVSSVFDIGV--RVVNDEL--
--YRKTLEEIVRSLD------KMENANIPSVSLSKREFCFQNVKYMQLKVESFTIHN-GQ
VPCHFEF------INKPDEESYCKQ---WLNANPSRGFLLPDSDVEIDLELFVNKMTATK
L-------NSGEDKIEDILVLHLDRGK--D-----YFLSV--------------------
-----------------SGNYLPSC---FGSPIHTLCYM------REPILDLPLETISEL
----------TLMPVWTGDDGSQLDSPMEIP-----------------KELWMMVDYLYR
NAVQQEDLF----QQPGLRS--EFEHIRDCLDTGMID-----------------------
NLS--ASNHSVAEALLL--FLESLPEPV----------------------IC----YSTY
HNCLECSGNYTASKQ-VISTLPIFHKNVFHYLMAFLRELLKNSAKNHLDENILASIFGSL
LLRNPAG---------------H-QK----------LDMTE-KKKAQEFIHQFLCNPL--
------------------------------------------------------------
---
>gi|76671314|ref|XP_582780.2|	Bos taurus
------------------------------------------------------------
------------------------------------------------------------
-----MPSKLVSLGHSETASQQPTAQGCLCPE------------------GSMLKGLLPN
SDEEPVPC------LGSPAAGGRQGPERSPELP------------LDTPEQVSNEDPRAQ
ARPFTPKPPPPRPRLERALSLDE-KGWRKRRFRTSREDLTVR-----NGASPSGGSLQDE
VPGTPARSG--------------------------SPPCLSAS---LQEIPTARRAPGSG
GPSSWGNCLSGMISTSLDLLHR-----------------------EGASAG---------
------------------------STPRLASLLSPRPLPAMARNMASEGLRTANKVDPDH
ADYK-----LRLQARLFRAHS--------SLGPGRPPSPLAYDDC---------------
-------SLHSSRSTFS------------------------------LLAPIRAKDVRSR
SYLEGSLLATG-------------------------------------------------
------------------------------------------------------------
-----ALMGAD----------ELARYFPDRSVALFVATWNMQGQKELPPN---LDELLLP
AEADLAQ---------DLYVVGVQEG-CSD-------------RREWEARLQETLGPH--
----YVMLYSAAHGALYMAVLIRRDLIWFCSEVESSTVTTRI---VSQIKTKGALGVSFT
FFGTSLLFITSHFTSGDGKVGERLVDYSKTVQGLALP----KNVPDTSPYRSDAADVTTR
FDEVFWFGDFNFRL--SGGR---AAVEAILKQDLSSSVQA-------LLQHDQLTREMQR
GSIFKGFQE-PDIHFLPSYKFDVGKDS---YD----TTSKQRTPSYTDRIL--YRSR--H
Q-----------------GDICPVK-YSSCPGVRTSDHRPVYGLFRVKV--RP-------
------------------------------------------------------------
------------------------------------------------------------
-------------------------GR--D-----NIPLA--------------------
-----------------AGKFDRDL---Y------LLGI------KRRISR---------
------------------------------------------------------------
------------------------------------------------------------
--------------------------------------------------------EIQR
QQALKSQHASAICTVS--------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
---
>gi|24639220|ref|NP_569962.2|	Drosophila melanogaster
------------------------------------------------------------
------------------------------------------------------------
-MDTLSEAVANGTATAATRTTKDIVKERFKEDETIEYIFE----------AYQIKGPEYS
NRLLAL--------------VSSQSGGTFAIIA---------FSYLRTPLSSANELIINK
VFAIDHN---------FQLRQDS-------KSSITTQQFDLS-----TAEDGPIKYYYYA
TESHHYEE---------------------------FVAKVISF-----KSTMAQHDPETV
LNFRWLNDYR--------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------QIGEVK
------------------------------------------------------------
------------------------------------------------------------
-----QELKKR-----------ESEYIVYKDIIIYCATWNVNNKTCSDSNNP-LRAWLAC
SEKPP-----------DIYAIGLQEL-DTPTKAMLNSTQVQAIEKQWIDKMMDSVHPD--
--VEYEILMSHRLVATMLTVIVRKQLRQHIIRCRPKSVARGI---FNTLGNKGGVAISLQ
LNEGNICFVNSHLAAHMGYVEERNQDYNAIVEGIRFD---------------DGRTI-SD
HDHIFWVGDLNYRI--QEPP----GQQRPGPLSDAQTYEL-------LLQYDQLRQEMRR
GKCFEGYTE-GEIKFRPTYKYDPGTDN---YD----SSEKQRAPAYCDRVL--WK-----
G-----------------TRIEQLA-YNSIMEIRQSDHKPVYAVFQVKV--KTRDEVK--
--YKRVQEEVLKAVD------KRENDNQPQINVEKTVIDFGTVRFNEPSTRDFNVYNNCP
LPVDFSF-------KEKDIHAICEP---WLHVDPRQDSLLIDSARSIRLKMNANVRTIAG
L-----LRKIRASDNFDILILHVENGR--D-----IFITV--------------------
-----------------TGDYQPSC---FGLSMETMCRT------DRPLSEYS-------
-----------QDQIKQLMNDESPEYRVTMP-----------------REFFLLIDYLYR
QGSKQVGAFPSYDSRLSLGA--QFNSVRDWLDTWSDD-----------------------
PFP--ANAETAAQALLL--LLDLPEHAL----------------------------LEPV
VENLLECTNKSQAMD-YISLLSPPKRNVFMHLCMFLRA---GIESQFYDLHQVASTFGRI
LLRSTER-----------------------------AAWMDYHSRCIQFMRLFIDTDVEA
MGNGN-----------------------------EGAGTGTGSGSGTRAGLQA-------
---
>gi|118089291|ref|XP_426250.2|	Gallus gallus
--------------------------------------------------MTMLFLVGKQ
RVSPKHGLWDGLRAGVGGGARRLSHTRGEQSVKEEECGQAQQCRAGTASGGPGCRGQAVG
AQAASWYHRDISRVVAEELLAKAGRDGCFLLRDSESIAGAYALCLLFQRHVHTYRILPDE
EGLLSV------------QTIQGIQAKCFRSLP----------ELISAYQQPNNGLVTPL
LYPVHRLREA------ADEDSDGEDGRGGHVGSMVPAGVGPRQLLAGVNGGSTGPGAPPT
HPHISQQLQLRLQEQVHSSPSSD------------FMGFMADYLAQHLPLDLAALRSGHP
QLRHLSAALVTACRALHSEIDFTL---------------------AGLETLARVFDPPVS
P-RSPAREQGFSASSPDLELLLSKISAVNHLLSSLEKKVLMSLQDTVSRHNLALPSPVSP
LPDT-----KPMATQCFEVKVGKSQRAALTVDVEEGTVTITKRGGGSPE-----------
-------EVIPQDKILQ----------------------------LIKYQSVQSKVRLVY
NRDLQRSLSKDFVFPSAKKREAFCQLL---------------------------------
------------------------------------------------------------
-----QLMKIQ-----------HSNLDEPDLISIYVGTWNMGSTP---PPRS-LASWLTS
RGLGHTQDETTACIPHDIYVIGTQEN-SLG-------------DREWVDFLRASLKTLMA
--IDYQVVALQCLWSIKMVVLVKPEHKRRISHVHTSSVKTGI---ANTLGNKGAVGVSFL
FNGTSFGFVNCHLASGSEKTHRRNQNYSDILRSLALG-----------DKRLSAFDLTLR
FTHLFWFGDLNYRL--DM------DVQDILTHITKKEFDI-------LLAMDQLNLEREK
NKVFLQFRE-GDISFPPTYRYERGSRDSYMWQKFKTTGMRINVPSWCDRIL--WKSL--P
E-----------------THLVCSS-YGCTDDIVTSDHSPVFATFEVGVTSQFVPKKG--
--KDKGMWSPLACIEWDSIEVIVKTASRSKCYIEFHSYCLEEAQ-RSGENTSQSCDVPGF
LRMCWSAKQLPVLKPVVAQVEHLEQVGTPSLLPAKQLQGIVAQVQDLQLPQTEAGEAVQG
VQGQVEHRQLSQCLKRSLLDVH--------------------------------------
------------------------D---VVVAEVQLSQL------WGALEDAH-------
---------------------------------------------------WQL------
------------------------------------------------------------
AQPVSGQVQHPQ-------CSEAAQEPP-------------------------------H
HVALQAIG-----RQVQHLYTPQCTESHCIVPVVLVQAV---------------------
------------------------------------GAQQQ-------------------
------------------------------------------------------------
---
>gi|148708202|gb|EDL40149.1|	Mus musculus
------------------------------------------------------------
----------------------------------------------------------MP
AMVPGWNHGNITRSKAEELLSRAGKDGSFLVRASESIPRAYALCVLFRNCVYTYRILPNE
DDKFTV------------QASEGVPMRFFTKLD----------QLIDFYKKENMGLVTHL
QYPVPLEEEDAI----DEAEEDTVESVMSPPELPPRNIPMSA-----GPSEAKDLPLATE
NPRAPEVTRLSLSETLFQRLQSMDTSGLPEEHLKAIQDYLSTQ----LLLDSDFLKTGSS
NLPHLKKLMSLLCKELHGEVIRTL---------------------PSLESLQRLFDQQLS
PGLRPRPQVPGEASPITMVAKLSQLTSLLSSIEDKVKSLLHEG--SESTNRRSLIPPVTF
EVKSE-SLGIPQKMHLKVDVESGKLIVKKSKDGSEDKFYSHKKILQLIKSQKFLNKLVIL
VETE---KEKILRKEYV-------------------------------FADSKKREGFCQ
LL----------------------------------------------------------
------------------------------------------------------------
-----QQMKNK-----------HSEQPEPDMITIFIGTWNMGNAP---PPKK-ITSWFLS
KGQGKTRDDSADYIPHDIYVIGTQED-PLG-------------EKEWLELLRHSLQEVTS
--MTFKTVAIHTLWNIRIVVLAKPEHENRISHICTDNVKTGI---ANTLGNKGAVGVSFM
FNGTSLGFVNSHLTSGSEKKLRRNQNYMNILRFLALG-----------DKKLSPFNITHR
FTHLFWLGDLNYRV--ELPT---WEAEAIIQKIKQQQYSD-------LLAHDQLLLERKD
QKVFLHFEE-EEITFAPTYRFERLTRDKYAYTKQKATGMKYNLPSWCDRVL--WKSY--P
L-----------------VHVVCQS-YGSTSDIMTSDHSPVFATFEAGVTSQFVSKNGPG
TVDSQGQIEFLACYA------TLKTKSQTKFYLEFHSSCLES--FVKSQEGENEEGSEGE
LVVRFGE-TLPKLKPIISDPEYLLDQHILISIKSSDSDESYGEGC-IALRLETTEAQHPI
Y-TPLTHHGEMTGHFRGEIKLQTSQGK--MREKLYDFVKTERDES---------------
-----------------SGMKCLKN---LTS--HDPMRQ------WEPSGRVP-------
--------------------------ACGVS-----------------SLNEMINPNYIG
MGPFGQPLHGKSTLSPDQQ-----------LTAWSYD-----------------------
QLPKDSSL----------------------------------------------------
-----GPGRGEGXXXXXXXPTTSVAKEVFIF----------HSQPRSLPQGARGKTWGS-
------------------------------------------GKGGSSAPGGPAADEARD
V-----------------------------------------------------------
---
>gi|6322189|ref|NP_012264.1|	Saccharomyces cerevisiae
------------------------------------------------------------
---------------------------------------------------MRLFIGRRS
RSIVISSNNYCLSFQRLRSIPGASSQQRQLSKTPSVTIKSYPDTDLSSDSNYLEVKSCIF
NGLLGLVCLNGDIYVAVISGVQNVGFPRWKLID-----------HQVRPSESIYKVLDVD
FYSLENDVFD------YLLCERSEQNYDKLIHEHPCGPLKKL-----FSDGTFYYSRDFD
ISNIVKNHG-----LSHNLEYTVDNQDLSFIWNANLASEVINW----RSKISNEEKQLFA
NAGFLTFVIRGYCKTALIEDGPNTASITIISRISTESKQDTLEL-EGISEDGRVSLFVET
EIVVTTEKFIFSYTQVNGSIPLFWESVESQLLYGKKIKVTKDS-------IEAQGAFDRH
FDNL-----TSKYGVVSIVNI--------IKPKSESQEKLALTYKDCAESKGIKITNIEY
SSSVL--TKSPHKLLYL--------------LKQDIYEFGAFAYDISRGIYFAKQTGVLR
ISAFDSIEKPNTVERLVSKEVLELTTNEIDVFELTSPFLDAHDKLWSENYYWLDRTYTKH
TKNSGKYTKVYSKLFGSRVRLYDPLHIYIS------------------------------
-----QYLKQL-----------RSKYTFEKDISIFAGTFNISGKI---PKDD-IKDWIFP
KSMSKEDEMA------DLYVIGLEEVVELTPGHMLATDPYV--RQFWEKKILTLLNGPGR
K-KKYIRLWSTQLGGILLLLFMNETEYSKVKHIEGDVKKTGF---GGMASNKGAVAVSFK
YSATRFCVLVSHLAAGLENVEQRHNDYKTIAKSIRFS---------------KGLRI-KD
HDAIIWMGDFNYRI--LM------SNEDVRRKIVSKEYAS-------LFEKDQLNQQMIA
GESFPYFHE-MAIDFPPTYKFDPGTKN---YD----TSEKMRIPAWTDRIL--SR-----
G-----------------EVLEQLE-YKCCEDILFSDHRPVYAIFRARV--TVVDEQKKT
TLGTQIYEKIMERLE------GLDDDEKIAV-LSDDAFVIESFEGSDSIAGPTHSPTPIP
EPKRG-----RKLPPPSSDL---KK---W-------------------------------
---------------------WIGSGK--Q-----VKVVL--------------------
-------------------DVDPAV---YMI---------------NPKRD---------
------------------------------------------------------------
------------------------------------------------------------
PNP----------------FVENEDEPL--------------------------------
----------------FIER----------------------------------------
------------------------------------------------------------
------------------------------------------------------------
---
>gi|149745642|ref|XP_001491905.	Equus caballus
------------------------------------------------------------
---------------------MECRSLAQRADSAAAWKTGGGARRRSLSGQALGSGSRLW
LPAPALSRSSHDAPRGGRVYGRGGQRRRIRPQSARPHTVE----------GMEMKGPLRE
PCALTL----------------AQRNGQYELII----------QLH------EKEQHVQD
IIPINSH---------FRCVQEA--EETLLIDIASNSGCKIR-----VQGD-WTLERRFE
IPDEEHCLK--------------------------FLSEVLAA----QEAQSQLLVPEQK
DSSSWYQKLDTKDKPSGFSGI------------------------LGFEDN---------
-----------------------FSSMNLDKKINSQNQPMGIH--------REPPPPPPS
VNRM-----LPR------DKE--------ASNKEQPK-----------------------
-------VTNTMRKLFV------------------------------PNTQSGQREGLIK
------------------------------------------------------------
------------------------------------------------------------
-----HLLAKR-----------EKDYVNIQTFRFFIGTWNVNGQS---PDSG-LEPWLNC
DPSPP-----------DIYCIGFQEL-DLSTEAFFYFESVK--EQEWSMAVERALHFK--
--AKYKKVQLVRLVGMMLLIFARKDQWRYIRDIATETVGTGI---MGKMGNKGGVAVRFV
FHNTTFCIVNSHLAAHVEDFERRNQDYKDICARMSFV---------VPNQTLPQLNI-MK
HDVVIWLGDLNYRL--CMP-----DANEVKSLINKNDLQR-------LLKFDQLNIQRTQ
KKAFADFIE-GEIKFTPTYKYDSKTDR---WD----SSGKCRVPAWCDRIL--WR-----
G-----------------TNVNQLH-YRSHMELKTSDHKPVSALFNIGV--KVVDERR--
--YRKVFEDIVRIMD------RMENDFLPSLELSRREFVFENVKFRQLQKEKFQISNNGQ
VPCHFSF------IPKLNDSQYCKP---WLRAEPFEGYLEPNETVDISLDVYVSKDSVTI
L-------NSGEDKIEDILVLHLDRGK--D-----YFLTI--------------------
-----------------SGNYLPSC---FGTSLEALCRM------KRPIREVPVTKLIDL
EEDSFLEKEKSLLQMVPLD-EGASERPLKVP-----------------KEIWLLVDHLFK
YACHQEDLF----QTPGMQE--ELQQIIDCLDTSIPE-----------------------
TIP--GSNHSVAEALLI--FLEALPEPV----------------------IC----YELY
QRCLDSAQDPQICRQ-VISQLPRCHRNVFRYLMAFLRELLKFSEYNNVSTNMIATLFTSL
LLRPPPN---------------LMAR----------QTQSD-RQRAIQFLLGFLLGSDED
------------------------------------------------------------
---
