>gi|20521960|dbj|BAB33332.2|	Homo sapiens
KSTFGCLPRTSCARRDNPRASSRNRTIQRDNPRTSCAQRDNPRASSPNRTIQQENLRTSC
TRQDNPRTSSPNRATRDNPRTSCAQRDNLRASSPIRATQQDNPRTCIQQNIPRSSSTQQD
NPKTSCTKRDNLRPTCTQRDRTQSFSFQRDNPGTSSSQCCTQKENLRPSSPHRSTQWNNP
RNSSPHRTNKDIPWASFPLRPTQSDGPRTSSPSRSKQSEVP-------------------
------------WASIALRPTQGDRPQTSSPS---RPAQHDPPQSSFGPTQYNLPSRATS
SSHNPGHQSTSRTSSPVYPAAYGAPLTSPEPSQPPCAVCIG-HRDAPRASSPPRYLQHDP
FPFFPEPRAPESEPPHHEPPYIPPAVCIGHRDAPRASSPPRHTQFDPFPFLPDTSDAEHQ
CQSPQHEPLQLPAPVCIGYRD-APRASSPPRQA-PEPSLLFQDLPRASTESLVPSMDSLH
ECPHIPTPVCIGHRDAPSFSSPPRQAPEPSLFFQDPPGTSMESLAPSTDSLHG--S---P
VLIPQVCIGHRDAPRASSPPRHPPSDLAFLAPSPSPGSSGGSRGSAPPGETRHNLEREEY
TVLADLPPPRRLAQRQPGPQAQCSSGGRTRSPGRAEVERLFGQERRKSEAAGAFQAQDEG
RSQQPSQGQSQLL--RRQSS----PAPSRQVTMLPAKQAELT-RRSQADPPHPRSPEKRP
EGDR-------QLQGSPLPPRTSARTPERELRTQRPLESGQAGPRQPLGVWQS-QEEPPG
SQGPHRHLERSWSSQEGGLGPGGWWGCGEPSLGAAKAPEGAWGGTSREYKESWGQPEAWE
EKPTHEL----PRELGKRSPLTSPPE-------NWGGPAES-SQS--WHSGTPTAVG---
----WGAEGACPYPRGSERRP------------ELDWRDLLGLLRAPGEGVWARVPSLDW
EGLLELLQARLPRKDPAGHRD-----DLARALGPE---------LGPPGTNDVPEQESHS
QP--EGWAEATPVNGHSPALQSQSPVQLPSPACTSTQ---WPKI--KVTRGPATATLAGL
EQTGPLGSRSTAKGP-------SLPELQFQP--EEPEESEPSRGQDPLTDQKQADSADKR
PAEGKAGSPLKGRLVTSWRMPGDRPTLFNPFLLSLGVLRWRRPDLLNFKKGWMSILDEPG
EPPSPSLTTTSTSQWKKHWFVLTDSSLKYYRD-STAEEADELDGEIDLRSCTDVTEYAVQ
RNYGFQIHTKDAVYT--LSAMTSGIRRNWIEALRKTVRPTSAPDVT--KLSDSNKENALH
SYSTQKGPLKAGE--QR--------AGSEVISRGGPRKA--DGQRQALD-----------
--------------YVELSPLTQASPQRARTP-AR-TPDRLA--KQEELERDLAQRS---
-------------EERR--K-------WFEATDSRTPEVPAGEGPRRGLGAPLT--EDQQ
NRLSEEIEK----KWQELEKLPLRENKRVPLTAL---------------LNQSRGERR-G
PPSDGHEALEKEV-QALRAQLEAWRLQ--------------------GEAPQSALRSQED
GHIPPGYISQ--EACE-----RSLAEMES--SHQQVMEELQRHHERELQRLQQEKEWLLA
EETAATASAIEAMKKAYQE------ELSR--------ELSKTRSLQQGPDGLRKQHQSDV
EALKRELQVLSEQ--YS--QKCLEIGAL--MRQAEEREHTLRRCQ-QEGQELLRHNQELH
GR----------------------------------------------------------
-LSEEIDQL---RGFIASQGMGNGCG----------------------------------
-----------------RSNERSSCELEVL-LRVKENELQYLKK----------EVQCLR
DELQMMQKDKRFTSGKYQDVYVELSHIKTRSEREI--EQLKEHL----RLAMAALQEKES
MRNSLAE-----------------------------------------
>gi|126277707|ref|XP_001377867.	Monodelphis domestica
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
----------------------------------MELYFGE-------------------
------------YKHVQQEYGVHLRLESE------ETKKSRLSQNAKTGSYGVSIRVQGI
DGHPYIVLNNTERCLAGIPFAENGPSFTSPGINDLGLHSNMDPRLEEKASE---------
---------------------------------EIQFPENPYVQPSAFRSLKPASLYEGK
NGLLEHKDSSLKSSSMLNFQR-HPELLQPYNPEKNELNLETHKSPECNWTKMLTDETKN-
------------DKRSRTCFSKPASSQPASMPSGDMSKCNVTAIRLCSSIVID--D---P
KKQASVCLNVQSCANEGLTT------------------GSSTPSEKPLTTIHPDTHQESK
KIRPDVLPFRRQDSAGPVLDGYRSRRSSSSSV---TPTSANSLYKFLLDDQDYAIHADNV
NRHENRRYIPFMPGTGRDIDTGSIPGVDQLIEKFDQKVGSQ--RRGRSGKRNRIHPDDRK
RSRSVDSAFPFGLQGDSEYLDEFSRNLGKSS---------EHLLRPSQVWQQKPLSRERR
LLSGGKH------------------TMVVQTSGKL---------------KEQGQDSLDG
QPRLSQLNNANKVHENKVNKDSGMMGPTILSAQNKKEEMKT-ATATVVLQNQAASIL---
----PDAGTKKISIKTLSS--------------ATNTQATPDLLKGQQELAQQTNEETAK
QILYNYLKEGSTDNDDATKRKVNLVFEKIQTLKSR---------AAGSAQGNNRVSDSSA
EVR-ELLEQRNKLNREVSELQKQLNLEIKNQQNIKEERDRMRSNLEELQSQHEEKEKETL
TLQKRLDDSEMELRK-------NLEELFQVK--MEREQHQTEIRDLQDQ-----------
------------------------------------------LSEMHDELDNAKHSDDGE
K----------GALIEELLQTKRDLQDILIAK-EEQEDLLRKRERELTALKGALKEEVSS
HDQEMDKLKEQYDAE--LQALRESVEEATKNVAVLAHRSSTSQPTQ--VEAENQVKILTE
ENEKLQKKIKELE--VS---------MTKLQTVVDEMKLDDVKMKEKIK-----------
---------KYEGEKQQLEEALLSAREQEKEI-LSAKRTLEN--QLEDIKKNLSQAT---
-------------QEQQ--H-------LSEKLQDETDQKEQLRRLKNEMENERWQLDKTI
EKLHKEMAD----------IVEVSRTSTLELQNQ---------------LDEYKEKNRRE
LAEMQRQLKEKTM-EAEKSRLTVIKMQ--------------------DEMRLMEEELQDY
QRAQDEALTK-RQLLE-----QTLKDVEYELETKSHLKEDRSRQVKQMEDKISQLEMELD
EERNNSDLLSDRITRSREQI-----EQMRS-------ELLQERAVRQDLECDKISLERQN
KDLKSRMVHLEGS--YRS-SKEGLVVQM--EARISELEDRLENEE-RDRANLQLTNRRLE
RK---------------------------------------------VKELVMQVDDEHL
SLTDQKDQL---SLRLKAMKRQVEEAE---------------------------------
-----------------EEIDRLESSKKKL-QRELEEQMDV-------------NEQLQG
QLNNMKKNLRHKKMPSKVLDDLDDDDDD---------DDFSTDGGSLYEAPMGYPFSKEN
DPTKSASASHGV------------------------------------
>gi|74199130|dbj|BAE33111.1|	Mus musculus
------------------------------------------------------------
------------------------------------------------------------
---------------------------------------------------------GNS
RNPSPHRTNKDIPWASFPLRPTQSDSPRTSSPSRTKQNQVP-------------------
------------WASISLRPTQGDKPQTSAPT---RLAHNDPPQ-----QYSPSLATTSS
SSHNPGHSSASRTSSPLHAAPRGAPQTSLESSQPPCTVCIG-HRDAPRASSPPRYFQYDP
FPFFPDPRSSESESPHHEPPYMPPAVCIGHRDAPRATSPPRHTQFDPFPFLPDTSDADNE
--SPQHDPPQFPPPVCIGYRD-APRASSPPRQF-PEPS-FFQDLPRASTESLVPSTDSMH
EPPHIPTPVCIGHRDAPSFSSPPRQAPEPSLFFQDPPGTSMESLAPSIDSLHG--C---P
LLPPQVCIGHRDAPRASSPPRHPPSDIGLLAPSPPPG-SSGSRGSAPPGETRHNLEREEY
TMLADLPPPRRLAQRGPEPQAQGSNEGRTRSPGRAEVERLFGQERRKSEAPGAFQTRDEG
RSQRPSQAQSQL---RRQSS----PAPSRQVTKPSAKQAEPT-RQSRTGSPHPKSPDKRP
EGDR-------QLQRTSPPARTPARPPERKAQIERHLESGHTGPRQSLGGWQS-QERLSG
PQSPNRHPEKSWGSQKEGPSLGGWPELEGPSLEGI------WRGPPQEHREQWGHSEAWE
EPPSNGIQGAPPRGQGRLQELSRPHQPTPSSENSWAGPAEC-SCA--LQPEASTAVG---
----WRAEGTSPHQRSAERPP------------DLDWRDLLGLLRAPEDGAWTRLPRLDW
EGLLELLQARLPQKDPARHWH-----DPAKASGPE---------QGSSGTEDTLKTEPQT
QP--EGRAKATLANGHRPGQQSESPAQLPSPACTSTQ---WPTT--KVTSGPETSPLAAL
EQIDHLESH-------------SPPDLEFQP--EEPEASEPSRGEDSRAVQKQADS----
------------------------------------------PDLLNFKKGWMSILDEPG
E-------------WKKHWFVLADSSLKYYRD-STAEEADELDGEIDLRSCTDVTEYAVQ
RNYGFQIHTKDAVYT--LSAMTSGIRRNWIEALRKTVRPTSAPDVT--KLSDCNKENTLH
GYGTQKSSLKIGE--QR--------TGSEVIGRGGPRKA--DGPRPSLD-----------
--------------YVELSPLAPSSPQRMRTL-SRSTPERPT--KQEDLERDLAQRS---
-------------EERR--K-------WFESTDGRTPETPSGDGSRRGLGAPLT--DDQQ
SRLSEEIEK----KWQELEKLPLRENKRVPLTAL---------------LNQAHNDRRRG
PTSDSHEALEKEV-QSLRAQLEAWRLR--------------------GEAPQNAPRLQED
SHIPPGYISQ--EACE-----RSLAEMES--PHQQVMEQLQRHHERELQRLQQEKEWLLA
EETAATASAIEAMKKAYQE------ELSRE--------LSKTRSLQQGPESLRKQHQLDM
EALKQELQVLSER--YS--QKCLEIGAL--TRQAEEREHTLRRCQ-QEGQKLLRHNQELH
SH----------------------------------------------------------
-LSEEIDRL---RSFIASQGTGNSCG----------------------------------
-----------------RSNERSSCELEVL-LR---------------------------
------------------------------------------------------------
------------------------------------------------
>gi|149052973|gb|EDM04790.1|	Rattus norvegicus
----------------------------MSNKKPELIDLLLISTNPFDFPFVSQGEVTVA
SIDDSEELLATDNAIDILGFSPEEKVGIYKLTGAVMHYGNMKFKQKQREEQAEPDGTEVA
DKAGYLMGLNSAEMLKGLCCPRVKVGNEYVTKGQNVQQVTNSVGALAKAVYEKMFLWMVT
RINQQLDTKQPRQYFIGVLDIAGFEIFDFNSLEQLCINFTNEKLQQFFNHHMFVLEQEEY
KKEGIEWEFIDFGMDLAACIELIEKPMGIFSILEEECMFPKATDTSFKNKLYDQHLGKSN
NFQKPKPAKGKAEAHFSLVHYAGTVDYNIAGWLDKNKDPLNETVVGLYQKSSLKLLSFLF
SNYAGAEAGDSTGGKKGGKKKGSSFQTVSAVFRENLNKLMTNLRSTHPHFVRCLIPNETK
TPGVMDHYLVMHQLRCNGVLE-GIRICRKGFPS-RILYADFKQRYRILNASAIPE-----
-GQFIDSKNAS-EKLLNSIDVDREQFRFGHT---------KVFFKAGLLGLLEEMR---D
EKLVTLMTRTQAVCRG-------------------YLMRVEFKKMMERREAIFCIQYNVR
SFMNVKH-----------------WPWMN------LFFKIKPLLKSAEAEKEMATMKEDF
ERAKEELARSEAR--RKELE----EKMVSLLQEKNDLQLQV--QSETENLMDAEER----
--CE-------GLIKSKIQLEAKVKELNERL---------EEEEETNSELVAK-KRNLED
KCSSLKR------------------DIDDLELTLT-------------------------
----------------KVEKEKHATENKVKNLSEEMTALEE-TISKLTKEKKSLQEA---
----HQQTLDD----------------------LQVEEDKVNGLMKINVKLEQQTDDLE-
GSLEQEKKLRADLERVKRKLE-----GDLKMSQES---------IMDLENDAQQLEEKLK
KKE-FEMSQLQTRIDDEQILSLQLQKKIKELQARTEE---LEEE---IEAEHTVRAK---
-----IEKQRSDLAR-------ELEEISERL--EEASGATSAQIEMNKKREAE-------
------------------------------------------FQKLRRDLEEATLQHEAT
A----------ATLRKKHADTVAELGEQIDNL-QRVKQKLEKEKSELKMEIDDMASNIEA
V--------SKSKSN--MERMCRSV---EDQFNEIKAKDDQQTQLI--HDLNMQKARLQT
QNGELNHQVEEKE--SL---------VSQLTKSKQALTQQLEELKRQLE-----------
---------EETKAKNALAHALQSSRHDCDLL-REQYEEEQE--GKAELQRALSKAN-SE
VAQWRTKYETDAIQRTE--E-------LEEAKKKLAQRLQEAEENTEASNSKCASLEKTK
QRLQGEVDD------LMLDLEKANTA-CATLDKK---------------QRNFDKVLAEW
KQK--LDESQAEL-EAAQKESRSLSTE---------------IFKMRNAYEEVVDQLETL
RRENKNLQEEISDLTE---------QIAETGKNLQEVEKTKKQMEQEKSDLQAALEE--G
SLEHEESKILRVQLELSQV------KSELD---------RKVTEKDEEIEQIKRNSQRAV
EAMQSVLDAEIRS--RN--DALRLKKKM--EGDLNEMEIQLSHAN-RQVAETQKHLRTVQ
GQ----------------------------------------------------------
-LKVSISQF---GT----------------------------------------------
-----------------SGLMVHTEALPSL------------------------------
-------------------------------------------------LVSLQGFPAAP
GRCPEKQ-----------------------------------------
>gi|149720701|ref|XP_001496902.	Equus caballus
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-----------------------MSLLKPSGLKAPTKILKP-------------------
------------GSTTLKTPAAVAAPVEKVIS---SEKASSSPSSE---TQEEFVDDFRV
GERVWVNGNKP-----GFIQFLGETQFAPGQWAGIVLDEPI-GKNDGSVAGV--------
---------------------------------RYFQCEPLKGIFTRPSKLTRKVQAEDE
ANGLQTTHASRATSPLSTSAA-SMMSSTSATPS-NIPHKSSQPAPKEPSATSQISNLTKT
ASESISN-----LSEAGSIKKGERELKIGDRVLVGGTKAGVVRFLGETDFAKGEWC---G
VELDEPLGKNDGAVAGTRYFQCQPKYGLFAPVH--KVTKIGFPSTTPAKAKAAAVRRVMA
TTPASLKRSPSASSLS-------------------SVSSVASSVSSKPSRTGLLTETSSR
YARKIS-GTTALQEALKEKQ----QHIEQLLAERDLERAEV--AKATSHVGEIEQE--LA
LARD-------GHDQHVLELEAKMDQLRTMV---------EAADREKVELLNQ-LEEEKR
KVEDLQF------------------RVEEESITKG-----------DLEQKSQISEDPEN
TQTKLEHARIKELEQSLLFEKTKADKLQRELEDTRVATVSE-KSR-IMELEKDLALR---
----VQEVTELRRRLESSKP-------------AGDVDMSLSLLQEISS-LQEKLEATHT
DHQREITSLKEHFGAQEETHQ-----KEIKALQVS---------TEKLSKENESLKSKLD
HAN-KENSDVIALWKCK------LETAIASHQQAMEE---LKVS---FSKGVGTETAEFA
ELKTQIEKMRLDYQH-------EIENLQNKQ--DSERSAHAKELEALRAKL---------
------------------------------------------MKVIKEKENSLEAVKSKL
D--------------KAEDQHLVEMEDTLNKL-QEAEIKV-KELEALQAKCREQARVLDN
VTSQLKAAEEKLVD---LDALRKASSEGKSETETLRQQLEAAENQI--KTLEIEKSAESD
KASSVTRELQGKE--LM---------LNNLQENLSEVSQVKEALEKELQ-----------
---------ILKEKFSDASEEAVSVQRSMQET-VNKLRQKEE--QFNALSSELEKLR-EN
LTDMEAKFRERD-EKEE--Q-------LIKAKEKLENDIAEIMKMSGDNSSQLTKMNDEL
RLKERNVEE------LQLQLTKANEN-ASILQKSIGEATLKAEQSQQEAAKKHEEEKKEL
LRK--LSDLEKKM-EMSHNQCQDLKARYEEASSETKAKHEEVLQNLQKMLSDTEERLKAA
KKENSDLLQEMVELKKQADKAKAAQTAEDAMQIMEQMTKEKTETLASLEDTKQTNEKLQN
ELDTLKENNLKNVEELNKS------KELLTVENQKMEEFRKEIETLKQAAAQKSQQLSAL
QEENVKLAEELGR--SR--DEVTSHQKL--EEERSALNNQLLEMK-KRESKLIKDTDEEK
AS-------LQKSISITSALLTEKDAELEKLRNEVTVLRGENASAKSLHSVVQSLESDKV
KLELKVKNL---ELQLKENKRQLSSSSGNTDTQA-------------------------D
EDERAQESQI-------DFLNSVIVDLQRK-NQDLKMKVEM---------MSEAALNGNG
DDFNNYDSDDQEKQSKKKPRLFCDIC-DCFDLHDT--EDCPTQA----QMSDDPPHSTHH
GSRSEERPYCEICEMFGHWATNCNDDETF-------------------
>gi|125987223|ref|XP_001357374.	Drosophila pseudoobscura
------------------------------------------------------------
------------------------------------------------------------
----------------------------ASRKVSKCGYLFVAPDWDFSNPLYRTKRWQRR
WFVLYDDGELTYSVDDYPETIPQACIDMTKVLEVTGAVEVTGHPNSIAITAPERVTFVKG
TSSEESQWWLNILAAFPKSKGRHKRSATLPGG---QVVGSLRQSSNM--DMSTKLGNRHS
SYHKDTLTSSQSAGNLLSSLDLSPSSTNTGGSTTV-TNTQGTVDDDEEDDGVETGEDVDE
E--------------------------------DEEDVQPRKSKPSTSCIIGQDENNRNA
GNEITNRVSQPTTCLLIEDIRRDEKTIKDIANTITNLSQQQNKRWSTAVNNALNNQHSSH
YHTHGHGQYQT-SRDETDFQVSSAASNNNNS---NKSPSSGGSERPKSLPLAANST---P
AIVSAIVKKIPPVMVL-SKTKTPTRLQLQLKP------AKHYQHERGDPDGGCNMDELCP
NYMAKTDELRSVKGGLSIKSSSSSSSGAS------KPSAKAATEESLNAKKGWLMKQDN-
RTGEWSKHWFTLS--GAALF----YYRDPLCEERGVLDGVLDVNSLTNVLPEPSASKQHA
FQLI-------TWDKQRLLLASLSPSSRNSW---------LAVLRSAAGLPQQ-LDTTTP
TTGAKQT------------------DIEQDFIKAQ------------------LQPVASP
ATTPGTPAGTGPHFSSDEEYRTASEGGRRDSLD-WGSPLSP-SPPVLRSCLRNRSLA---
----SLHKRSRSSPPSSRRSTV-----------DSVASDELPLLVVPEE-LLQPDRELK-
-------QQCETLRAEATLRE-----ARMSEL------------LTTLQRTEQQLTARLQ
EQQQQLNGELAQAKQSAAELMHSLSLQLSDSQCKIKQ---LEDR---LAQGIEENES---
-----LYKRLRELQAEGSQVA-SLSNLQRHK--MKRMDSLSDLTTISDIDPYCLQ-----
------------------------------------------RDSLAEEYNELRSRFEKA
V-----------NEIRAMKRELKQSQNQYDAL-ELAQAALQQKLERCQLEDGAQLQLMAA
RIQDLTLKYSSSERQ--VRALKQKL---AKSERRRSLSLKGKEQLEL-KLSELQRETIER
KSVESISPPTESS---SSESASQSPLNAHLLQRLHSLEHVLLGSKERLE-----------
------------QSLTQLQQIRAGQRSRRS---VSPMNDRKD--GLRQLERALAETCVMV
SEQMELTCVQDACHKCC--D-------LRQRVEKLSALQQQTETDLQRSEQLLEQRESDL
AQALEKCAS------QEQEQELLLRQ-RNELSDE---------------LGKQQERCKRL
EKR--LELLEREHGKQLECLREVYHNE-----------------------HVNAADEQSF
RKRYQLEIEQLRTLCE-----KGLSAMET--SHRRITCDLEQQHKLEIERLLAEKETALA
EETQATLAALDAMRKAHQS------EVQREVARFKQEFLRQVQRGEHMREDGTTLKEEEL
EELRLEILSFSEK--YS--IKCVENAAL--EEKLHLANSRLRHF--QQMQQLELRNKQFR
AH----------------LASEDPANDVHFVQGLTTDHTREGAHCEDSECAPEIVAEPRT
TTTLETSSD---TESIPNPQNPDPAPATANEFVE-------------QSLFVIPSHMLNC
SPVPAANQNQNQSPNSSDQMRAIQSEYPAL-EDGYEPCYRPFDIFAIYQNRL--SFQGLR
GSSTFGKSLRKSTAQTASPASSELIAPRYSSSTHTAPTTNPN------KPSHKQMFKTAA
VINMQLHEEKAQ------------------------------------
>gi|114609099|ref|XP_001163920.	Pan troglodytes
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-----------------MSWQQHYYGGSAAG----AAKFAPSPATA-------QLAGHSM
DYSQEMHLKMSKKIAQLTKVIYALNTKNDEHESA--------------------------
---------------------------------IQALKDAHEEEIQQILAETREKILQYK
SKVTEELDLRRKIQVLESSLEDHIKMKQQALTE--------FEAYKHRVEDMQLCAEAQH
VQRIVTMSREV-EEIRRKFEEKLRSFGQLQVQFEKDKRLALEDLQAAH-----------R
REIQELLKSQQD----------------------------HSASVNKGQEKAEELHRMEV
ESLNKMLEELRL-----------------------------ERKKLIEDYEGKLNKAQSF
YERELDT-----------------LKRSQLFTAESLQASKEKEADLRK------------
-----------EFQGQEAILRKTIGKLKTEL---------QMVQDEAGSLLDK-CQKLQT
ALATAEN------------------NVQVLQKQLD-------------------------
-----------DAKEGEMALLSKHKEVESELAAARERLQQQ-ASDLVLKASHIGMLQ---
----ATQMTQEVTIKDLESE-------------KSRANERLSQLEEERAFLRSKTQSLDE
EQKQQILELEKKVNEAKRTQQ--------EYYERE---------LKNLQSRLEDEVTQLN
EAHSKTLEEL--AWKHHMAIEAVHSNAIRDKKKLQMD----------LEEQHNKDKLN--
-----LEEDKNQLQQ-------ELENLKEVL--EDKLNTANQEIGHL-------------
------------------------------------------QDMVRKSEQGLGSAEGLI
A-------------------SLQDSQERLQNELDLTKDSLKETKDALLNVEGELEQERQQ
HEETIAAMKEEEKLK--VDKMAHDLEIKWTENLRQECSKLREELRL--QHEEDKKSAMSQ
LLQLKEREKNAAR--------------DSWQKKVEDLLNQISLLKQNLE-----------
--------IQLSQSQTSLQQLQAQFTQERQRL-TQELEELEE--QHQQRHKSLKEAHVLA
FQTMEEEKEKE--QRAL--E-------NHLQQKHSAELQSLKDAHRESMEGFRIEMEQEL
QTLRFELED---------EGKAMLASLRSELNHQ---------------HAAA-------
-----IDLLRHNHHQELAAAKMELERS-----------------------------IDIS
RRQSKEHICRITDLQE---------ELRHREHHISELDKEVQHLHENISALTKELEFKGK
EILRIRSESNQQIRLHEQDLNK---RLEKELDVMTADHLREKNIMRADFNKTNELLKEIN
AALQVSLEEMEEK--YL--MRESKPEDI---QMITELKAMLTERD-QIIKKLIEDNKFYQ
LE----------------------------------------------------------
LVNRETNFN---KVFNSSPTVGVINPLAKQKKKN--------------------------
------DKSP-------TNRFVSVPNLSAL-ESGGVGNGHP---------------NRLD
PIPNSPVHDTEFNSSKPLPQPVPPKGPKTFLSPAQ-------------SEASPVASPDPQ
RQEWFARYFTF-------------------------------------
>gi|118099530|ref|XP_001237034.	Gallus gallus
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
----MEHELVLHQLRCNGVLE-GIRICRKGFPS-RVLYADFKQRYRVLNASAIPE-----
-GQFMDSKKAS-EKLLGSIDVDHTQYRFGHT-----------------------------
-------------------------------------------------------KYNVR
SFMNVKH-----------------WPWMK------LFFKIKPLLKSAESEKEMANMKEEF
EKTKEELAKSEAK--RKELE----EKMVVLLQEKNDLQLQV--QAEADSLADAEER----
--CD-------QLIKTKIQLEAKIKEVTERA---------EDEEEINAELTAK-KRKLED
ECSELKK------------------DIDDLELTLA-------------------------
----------------KVEKEKHATENKVKNLTEEMAVLDE-TIAKLTKEKKALQEA---
----HQQTLDD----------------------LQVEEDKVNTLTKAKTKLEQQVDDLE-
GSLEQEKKLRMDLERAKRKLE-----GDLKLAHDS---------IMDLENDKQQLDEKLK
KKD-FEISQIQSKIEDEQALGMQLQKKIKELQARIEE---LEEE---IEAERTSRAK---
-----AEKHRADLSR-------ELEEISERL--EEAGGATAAQIEMNKKREAE-------
------------------------------------------FQKMRRDLEEATLQHEAT
A----------AALRKKHADSTAELGEQIDNL-QRVKQKLEKEKSELKMEIDDLASNMES
V--------SKAKAN--LEKMCRTL---EDQLSEIKTKEEQNQRMI--NDLNTQRARLQT
ETGEYSRQAEEKD--AL---------ISQLSRGKQGFTQQIEELKRHLEEEI--------
------------KAKNALAHALQSARHDCELL-REQYEEEQE--AKGELQRALSKAN-SE
VAQWRTKYETDAIQRTE--E-------LEEAKKKLAQRLQDAEEHVEAVNAKCASLEKTK
QRLQNEVED------LMVDVERSNAA-CAALDKK---------------QKNFDKILAEW
KQK--YEETQTEL-EASQKESRSLSTE---------------LFKMKNAYEESLDHLETL
KRENKNLQQEIADLTE---------QIAEGGKAVHELEKVKKHVEQEKSELQASLEEAEA
SLEHEEGKILRLQLELNQI------KSEID---------RKIAEKDEEIDQLKRNHLRIV
ESMQSTLDAEIRS--RN--EALRLKKKM--EGDLNEMEIQLSHAN-RMAAEAQKNLRNTQ
GT-----------------------------------------------LKCHENRKNIL
RLQDLVDKL---QMKVKSYKRQAEEAE---------------------------------
-----------------ELSNVNLSKFRKI-QHELEEAEER-------------------
-------------------------------------ADIAESQ----VNKLRVKSREIH
GKKIEEEE----------------------------------------
>gi|47225968|emb|CAG04342.1|	Tetraodon nigroviridis
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
---------------------------------------KDNPCRKFQANIFNKSKCQNC
FKPRESHLLNDEDLTQAKPIYGGWLLLAPEGTNF--------------------------
---------------------------------DNPLHRSRKWQR-RFFILYEHGLLRYA
LDEMVNALAHLPTTLPQGTI--NMNQCSDVVDGESRTGQKNSLCILTPEKEHFIRAECKE
IINGWQEALTVYPRTNKQNHKKKRKVDPQTHQEPGPAKVTVTS------SSSGGGI---P
SLPSSIASAERVPISRATLWQEESRW---------------TRATIPCSRSTSCISQLSQ
SHPD-------------------------------------TSATSQDDGSTIFT----G
RKVRVESGYFSLEKTKSEPF----PQPAQHSQPPQHLPLC--------------------
----------------------------------------SSAPSSSVGGLS--------
------------------------------------------------------------
-----------PRYNSESEPQLSPYQPSQDPLPSPGTLVSP-SCSAISSSQSSMDSE---
----PNGTTPILEGGKESNDR------------TCGGGNRLGRSGSEYT-ALSDVPRAR-
-----RLSYREAFRSEKRHQE----------LRAR---------TRSPGREEVARLFGQE
RRRSQIISRFEE--GQQADHMDTSSPSEPSADTTSSQ-----------RQGRS-------
----------------------ERRNLTNKHVCTYQNDSLPDSDTTSDEAQQK-------
------------------------------------------QDLLNFKKGWMTKLYEDG
M-------------WKKHWFVLTDQSLRYYRD-SIAE-------ECKEGACT--------
-----------------LSAMTSGIRRNWIQAIMKNVRPTIPPDVT--RSLPEKTNVMLE
PCPLKTSEPSSSPDIHRQPSGSSTSVPSSEPRKSRVRERRREGRSKTFD-----------
--------------WSEFKMEPNEKPLRERSE-TVDFSSSLS--TASSYCSPSSSSSSLA
SSPISASSIQASCVSGAPPP-------MIEDAEKENVWRKQGKMEVDHPAALHPCSDDQK
DFRSSDVQEEIEQRWHQVETTPLREEKQVPINTA---------------LRSSD----RL
PAHELAALLDSEL-EAQKRKQDVAQQQ-------------------IRTLKRSYTEAQDA
VDRHETDIQALQV--------KLASAMAEILASEEAVTRMRNELKLEQERSKEQEEEHSR
SETTLRAQLKESEDRLREV------EASLL-------ERNQALRHLERQQALQRDHMREI
QRLQERLQEVTAR------LNATEEGQVLKEERLRSQRQTLQESHEKEKQNLCKRLAEAE
NA----------------------------------------------------QKELQN
RVVEAEEQV---EALLRGKQGSAGKECWEEMQKL--------------------------
--QGELAQKT-------DMVESLRENVRRLEEEKGHLTCRC-------QELLNQIVEADR
EVNKFRNRLETEEADYNTLEHSYTRATQEFQKISLFLREKEDEI----RQTKEMYERLVE
RKEEDLKEAL--------------------------------------
>gi|109016677|ref|XP_001108773.	Macaca mulatta
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-MTLSQEQKRDFDSGSCFIVLGLLELEGKKKMSPLLRSICD-------------------
------------ITEIFNQYVSHDCDGAALT----KKDLKNLLEREFGAVLRRPHDPKTV
DLILELLDRDRNGRVDFNEFLLFIFKVAQACYYALGQATGLDEEKRARCDGKESLLQDRR
QEEDQRRFESRD---------------------RQLEEEPGQRRRQKRQEEERELAEGEE
QSEKQERLQQRDRQRRDEELW-RQRRERREQEE-RRAEEEQLQRCKGHETEAFPDEE---
-QQRRRELQEL-RRERREEKQQQRRERQERVLQEEEEKEWRKRERVHRQEEKLQEE---E
PQLQRELQEEEEQLQK-LEREQERREQRLKRQEEEERREQRLKRQEEEERREQLLKREEE
RLQQERR-----------------EQWLKREQE--ERREQWLKREQEEERRDQLLKREEE
EKRRQQEERREQRLKRQEEE----ERREQLLKREEEERLEQEERREQRLKREQEERREQR
LKRE-------QEERREQRLKREQEERREQL---------LKREEEEERLEQE-ERREQR
LKREQEE------------------RREQEERREQ------------------RLKREEE
ERLEQEKRREQLEERRQQWLRREQELAEEEQEQARERIKSQ-TPKWQWQLESEADAR---
----QSKVYSRPRKQEGQRRRQEQEEKRRRRERELQWQEEEQARRQQQEEEQRRDFTWQW
QAEEERQRGRQRLSARPSLRE-----QRERQLRAEERQQREQRFLQEEEKEQRRRQRRER
ERELQFLEEEEQLQRKEQQLQQQEEEELQREEREKRR---RQEQERQYREEEQLQQEEEQ
LLREEREKRRRQERERQYREDEELQQEEEQLLGEEREKRRRRERERQYRKEEELQQEE--
------------------------------------------EQLLREEREKRRRQEQER
E-------YRKEEELQQEEEQLLREEREKRSL-QERERQYRKEEELQQEEEQLLREEREK
RRLERERRYREEEEL--QQEEKQLLR--EEREKRRRQELERQYREE--EELQQEEEQLLR
EEQEKRRQEPERQ--YL--------EEEELQHQERKRRYRDEDQRRDLKWQWEPEKENAV
RNNRVYCKRRENEQFRQSEDSQVRDRQSQQDL-QPLLDEPQE--RGGKQEKRRWQQRDRH
FPEEEQLEREE--QKEA--K-------RRDRKFQEEKQLLREEKEKRVRQGRDRRFREEE
QLLQEREEQ----QLSRQERDRKFREEELRRQER---------------ERKFLEEEQQL
RRQELEQQLRHDRDRKFREEEQLLQER---------EEQQLSRQERDRKFLEEEQQLRQD
RDRKFREEEQLLQERE-EQQLRRQERDRKFLEEEQQLRQDRDRKFREEEQLLQEREEQQL
RRQERDRKFLEEEQQLRQDRDRKFREEEQLLQEREEQQLRRQERDRKFLEEEQQLRQDRD
RKFREEEQLLQEREEQQLRRQERDRKFR--EEEQQLRRQELERKF-LEEEQLRQETEEEQ
LH--------------------RQERDRKFLEEEQLRQEREEKQLRRQERDRKFREEEQL
RQEREEQQL---RRQERDRKFREEEQLPQEREEQ---------------------QLRRQ
DRDRKYRWEE-------EQLQLKKQEEQRL-RQERDGQYRAEEQFATQEKSRRQAQELWQ
EEEQKRRQERERKLREDHLRSQQEEEQRRRQVRETQSQEGKGHG----RLLEPGSHQFAS
VPVRSSPLYEYIQEQKSQYRP---------------------------
>gi|28574437|ref|NP_723879.2|	Drosophila melanogaster
------------------------------------------------------------
---------------------MSTTTITTTVPAAPSKSAPPTPTTTGAAGATTNARTADC
RKFTPNIFNKSKCSHCFRQREEHSAAALECNRVSKCGYLFVAPDWDFSNPLYRTKRWQRR
WFVLYDDGELTYSVDDYPETIPQACVDMTKVLEVTSAVEVTGHPNSIAITAPERVTFVKG
TSSEESQWWLNILAAFPKSKGRHKRSATLPGG---QVVGSLRPTSNGDLTLSTKLGNRHS
SYHKDTLTSSQSAGNLLSSLDLGPSSTKTAGS--PLTTTQSALADDEEDDGVETGEDVDE
---------------------------------DEEDETSVPRKSKTVSMGGQDENNRNA
GNEITNRVSQPTTCLLIEDIRRDEKTIKDIANTITNLSQQQNKRWSTAVNNALNNQH---
-HFGHHSQYQVTSRDETDFQMSSNSSSTKSQ--------NPASERPKSLPLASNST---P
AIVSAIVKKIPTVMEQGDKTKPTARLQLHLKS------PKHYQHERGDPDGGCNLDELCV
NYMAKTDELRSVGKANSKSSS--------------GQGKPPVKEESLNAKKGWLMKQDN-
RTCEWSKHWFTLS--GAALF----YYRDPLCEERGVLDGVLDVNSLTSVIPEPAASKQHA
FQLT-------TWDKQRLVLASLSPSSRNSW---------LAVLRSAAGLPQ--LDTPPK
QT-----------------------DIEQDFIKAQ--------------------LQQPS
SSPVTPGTPAGPHFSSDEEYRTASEGGRRDSLD-WGSPLSP-SPPVLRSCLRNRSLA---
----SLHKRSRSSPPSSRRSTV-----------DSVASDELPLLVVPEEMQPTESRELK-
-------QQCETLRAEASLRE-----ARMSEL------------LATLQRTEQQLTARLQ
EQQQQLNSELTQAKQSASDLMHNLGMQLTESQCQIKQ---LEDR---LAQGIEENEG---
-----LYKRLRELQAQDHSGGAALSNLQRHK--IKRMDSLSDLTTISDIDPYCLQ-----
------------------------------------------RDSLAEEYNELRSRFEKA
V-----------NEIRAMKRELKQSQNQYDAL-ELAQAALQQKLERRQHEDGAQLQLMAA
RIQDLTLKYSSSERQ--VRALKQKL---AKSERRRSLSLKGKEQLEL-KLSELQRETVER
KEGTPPESSSSESSSQS-------PLNAHLLQRLHSLEHVLLGSKERLE-----------
------------QSLTQLQQIRAGQRTRRS---VSPMNDRKD--GLRQLERALAETCVMV
SEQMELTCLQDSCHKCC--D-------LRQRVEKLSALQQQTETDLQRSEQLLEQRETDL
AQALEKCAS------QEQEQELLLQQ-RQELSEE---------------LGRQQERCRRL
EKR--LELLEREHGKQLECLREVYHTE-----------------------HANAADEQSF
RKRYQTEIEQLRTLCE-----KGLSAMET--SHKRLTMDLEQKHKMEIERLLAEKETALA
EETQATLAALDAMRKAHQS------EVQREVARFKQEFLRQVQRGEQMRGDGAKLKEEDL
GELRMEILAFSEK--YS--IKCVENAAL--EEKLHMANSKLRHF--QQMQQLELRNKQFR
AH----------------LASDDPSNDVHFVQGLTSD-AREDADCEDSEPAPQILGATAT
RTTATTTTT---ATATTTSAAPSETESNPDSDRETADSSRAPPEKMEQSLFVIPSHMLNS
SLVPAANASDQ------SQRSQLYRDLDGP-EDGYEPCYRPFDIFAIYQNRL--SYQGLK
GSSTFGKSLRKSAAQTSPASSEITTTTTAPTTDPK-------------KPSHKQMFKTAA
VINIQQQVAQEEKAQ---------------------------------
>gi|115768313|ref|XP_783376.2|	Strongylocentrotus purpuratus
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-------------------MSQAASPSAQEGG---DTKQSPAPKAG---KLESLPKEDLI
KYVKKQAMQVQKMKAKCEDLAKKNAELQSEKKSSPTSAASD-GKTSKMEEE---------
---------------------------------LKELREENEGVQAAYNAVQQQLAQAAE
VQETLQEALNAAS---------DQRSEAEKQQQ-AAVAQLEKANSKMKGLEEQIQCMEMK
EETMRTTFQCL-QEDQQAITNENKSLKEQITILTEARDQTIESLKALKQSMSSESS---K
D--DETKRRLDEVISE----------------------------KNELAQKISCLQEDQV
TMLQEMDSLKS------------------------------ELKSIMEEEKQVMMKAGVE
LQEQVENLQNQLADAEEGYK----TRLETLMQTSEEASGCA--QQLREELKTMNED----
--LA-------RLLQEKEDLIITKDEANARA---------NALEEKAHEWERE-KEREQT
KMEEYEE------------------DMSRLKVQVE-------------------------
-------------ELNTLKDQLTKLGAEKDSLKTEGERLSE-DNSRLTASMRETAEE---
----RTHLSEELESLKSGQTDL-----------NQVLQKQLDDTTKEKNSLKKNLQELE-
-------LSYGCLQKEATAKE-----AELEEIKRS---------VGEKEQQLEKLQE---
----DKLKKEEEMTKIEGSLQQSLDSAKEDAERMKEE---LKSVGEGVSSEENKKVEDLT
NAKGELEKIIKEMKEDVVRKDEEMKDLKEKL--EEVEGALESSREEKRKKAQL-------
------------------------------------------VEDLEKELTALKHTMMKG
D----------NEKIEEMCRKEEELQLALGTAKEDAQKKEEEMKELKEEMDVVKEQLMLI
RMAHLESMQQSSEYQQQVETLQKTQSSTSKGDDIRASKLESKK-----AELEQEKGEIEK
KVTALQKEVDQGK--KI---------IEELQEQKEQLQACITKLETEMS-----------
------------STMKELQDQMTLHEQEKETY-QASLQELLDQMTLHEQEKETYQARLQE
LQDQMTLHE----QEKE--T-------YQASLKELQDQMTLHEQEKETYQASLKELEQGA
VQERRRLEE------KILELEGSKEKYASNFEKL---------------KKASTAKVQEL
QEQ--IKELRSSR-EQGDNNKETQLVQ---------------LQDKISSLSDTVTQLQDA
NDSLQSRLDELLSEKN-----ALYADLETAMHQNEVMGQKESDITHQVNDLEVTRQKLIG
NLSYAK-NVLEPHQLCRPM------RESLE----KLLVLLLCRCPRTRGGDLRDGRPVFY
HGLETILVCKVIH------VRCMMDGAM--ASFPTRSNDAVVDLH-KTLISVTGLPADQH
LL----------------------------------------------------LLAHGE
RLTDGTTIL---HSLFKNHAFQNGDRIVYLYPKS--------------FPVKANFYIPPK
TPMVEALMTG-------KHLQVSENGFKVMWKQSIHYCHNL-------------IREALA
RQTGFIAYLNYNLKRKASLNQCAEEMKRCLH-----------------RLQAKAEFFLES
MSTDTQQYARQVATGF--------------------------------
>gi|6320562|ref|NP_010643.1|	Saccharomyces cerevisiae
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-----------------------------------MDEASHLPNGS--------------
---------------------LKNMEFTPVGF----------------------------
-------------------------------------IKSKRNTTQTQVVSPTKVPNANN
GDENEGPVKKRQRRSIDDTID-STRLFSEASQF---------------------------
-----------------------------------------------------------D
DSFPEIKANIPPSPRS---------------------------GNVDKSRKRNLIDDLKK
DVPMSQP-----------------------------------------------LKEQEV
REHQMKKERF----------------------DRALESKLLGKRHITYANSDISNKELYI
NEIK-------SLKHEIKELRKEKNDTLNNY---------DTLEEETDDLKNR-LQALEK
ELDAKNK-----------------------------------------------------
-----------IVNSRKVDDHSGCIE-EREQMERKLAELER-KLK--TVKDQVLELE---
----NNSDVQSLKLRSK----------------EDELKNLMNELNELKSNAEEKDTQLE-
-----------FKKNELRKRT-----NELNELKIK---------SDEMDLQLKQKQNESK
RLK-DELNELETKFSENGSQSSAKENELKMLKNKIAE----------LEEEISTKNSQLI
AKEGKLASLMA-----------QLTQLESKL--NQRDSQLGSREEELKKTNDKL------
------------------------------------------QKDIRIAREETVSKDERI
I-------------------DLQKKVKQLENDLFVIKKTHSESKTITDNELESKDKLIKI
LENDLKVAQEKYSKM-------------EKELKEREFNYKISE-----SKLEDEKTTLNE
KISNLAAENSQLK--------------NKIEDNSTATHHMKENYEKQLE-----------
-----------------------SLRKDIEEY-KESAKDSED--KIEELKIRIAE-----
-------------------N-------SAKVSEKRSKDIKQKDEQISDLTQNLKLQEDEI
SSLKSIIDR------YKKDFNQLKSEQSNIQHDL---------------NLQILNLENKL
IES--EDELKSLR-DSQKIEIENWKRK-------------------YNNLSLENDRLLTE
KESASDKEREISILNR---------KLDEMDKEKWNLQESKEKYKRELQKVITANDRLRR
EKEELNENS------------------------------NNIRIMEDKMTRIKKNYLSEI
TSLQEENRRLEER------LILNERRKD--NDSTMQLNDIISYYK-LKYHSEVRHNNDLK
VI----------------------------------------------------NDYLNK
VLALGTRRL---RLDTRKGEHSLNISLPDD------------------------------
-----------------DELDRDYYNSHVY-TRYHDYEYPL-------------RFNLNR
RGPYFERRLSFKTVALLVLACVRMKRIAFYRRSDD------NRL----RILRDRIESSSG
RISW--------------------------------------------
>gi|125809893|ref|XP_001346108.	Danio rerio
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
----------------------------------MSNNENS-------------------
------------ETDACNPPRRRKRSKDQPPSMRILLLGKSVSENSRVGNLILGRSAFDS
EAPADVVERVGGRLKDRHVTLINSPQLLNTQISDDQI-----------------------
---------------------------------TQTVRECVRLSDPGPHVVLLLLQHQQC
SAEDQERVEKLQDSFSERLLQ-HTLVLSTQEPT--EPNQILQKIIQKCSNRHFSLQRSSS
ADHLLQAFEDI-EKSNEGRHLIPAQYEAYKYFSVEQQATQRVSDCERLNVLVCGSDVSLK
SSISELILQHTHRKLESVRTDVDLHGRLINVLELPALFNTGLSEEEVMRQTLRCVSLCHP
GVHAFLL--------------------------------IIPDAPLNNEDRAEMEEIQKI
FSSRINKHIMIL-----------------IMQNSEHQTAELN-EETQAVIQSFGGRHQYF
NSET-------QVSTLMENIEKMLEENRGGVYST------ETFLEVQMKKLKK-YEEMKK
KLHSHDT----------HLLTQGLTECEDELRIVL------------------LGKTGVG
KSSTGNTILGREAFKAEDYFESVTKQSQRETSEINGRRITVIDTPGLFDTELSNEEI---
----QREIRHCIS--------------------MILPGPHVFLLLIPLGQRFTKEEEAS-
-----VKIIQETFGEHSLMFT-----------------------MVLFTKGDSLKNTTID
QCLDRPGSVVRKLIEACGNRYHVFNNNQPEDQRQVSE---LLEK---IDNMVKTNGGSFY
SCKMFREMEREKQEQ-------QMKILMDRV--QEAEEEKERMKMMMEEEEQKQ------
------------------------------------------EKERKRREEELKRERETF
R-----------HEIEEVRKEKEKLQIKYETETDRLMKRIETERKIREEENTEREEKYKT
QIVEKETKMKKKRET-----FRCEIEEMRREKEKLQIQHETETDRLM-KRIEDERESHET
ERKRREDEFNQRE--ER---------YKKEMKEKEEIQDELKSERERFK-----------
------------NENKELKQENENVKKESEKLQVKHQTDIEELMNRIKTEREIHETE---
RKKEGEEFNEREEQYKR--E-------IKEKEESEEKMQETMKRERQEWEKLKQEEKKRR
EEEQREFNE------KLIEEKKQLEREKEEL------------------QSKHEEEENKM
KIQ--REQMNRER-EKLMKRHEEEKER------------------MKMMMEEERQNQETE
RKRREEELKR--EIRE---------EEKHQREMKEEMKRERETFRHEIEEIKREKENLKT
EYETETDRLKNKLENEKKKCEEEHTEREEKYKAQIKEKMEEEREMREEMKRERERLKHET
EQVKTEKEKLQTR--YN-----TDTDRL--MNRIENERESHDKERKRREEEFKERKEQIK
TQ----------------------------------------------------------
-MSREREEW---EKLIQEEKKRREEDEKEKQILD--------------------------
-----------------EQIQKLKSEMEEIIKEKEKLEIKK-----------------QE
QLEDSEKRLKEERKTREDQQKTNEENLKLLEEHEEELKRRRVEW----REEYDREKEEKI
CSETDDSLQVF-------------------------------------
>gi|73994501|ref|XP_859601.1|	Canis familiaris
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-----------------------MSMLKPSGLKAPTKILKP-------------------
------------GSTALKTPAAVVAPVERTTS---SEKASGTPSSE---AQEEFVDDFRV
GERVWVNGNKP-----GFIQFLGETQFAPGQWAGIVLDEPI-GKNDGSVAGV--------
---------------------------------RYFQCEPLKGIFTRPSKLTRKVQVEDE
ANGLQTTPASRATSPLSTSAA-SMMTSSPGAPS-NIPHKSSQPTAKEPSTTSQISNLTKT
ASESISN-----LSEAGSIKKGERELKIGDRVLVGGTKAGVVRFLGETDFAKGEWC---G
VELDEPLGKNDGAVAGTRYFQCQPKYGLFAPVH--KVTKIGFPSTTPAKAKAAAVRRVMA
TTPASLKRSPSASSLS-------------------SMSSVASSVSSKPSRTGLLTETSSR
YARKIS-GTTALQEALKEKQ----QHIEQLLAERDLERAEV--AKATSHVGEIEQE--LA
LARD-------GHDQHVLELEAKMDQLRTMV---------EAADREKVELLNQ-LEEEKR
KVEDLQF------------------RVEEESITKG----------------------DLE
TQTKLEHARIKELEQSLLFEKTKADKLQRELEDTRVATVSE--KSRIMELEKDLALR---
----AQEVAELRRRLESHKP-------------AGDVDMSLSFLQEISS-LQEKLEAAHA
DHQREIISLKEHFGACEETHQ-----KEIKALQAA---------TEKLSKENESLKSKLD
HAN-KENSDVIALWKSK------LETAIASHQQAMEE---LKVS---FSKGVGMETTEFV
ELKTQIEKMRLDYQH-------EIENLQNKQ--DSERSAHTKEIEALRGKL---------
------------------------------------------MAVVKEKESSLEAIKAKL
D--------------KAEDQHLVEMEDTLSKL-QEAETKV-KELEVLQAKCNEQTKVIDN
FTSQLKATEEKLLD---LDALRKASSEGKSEIKKLRQQLEAAEKQI--KNLEIEKNTESG
KASSITRELQGKD--LI---------LNNLQKNLSEVSQVKEALEKELQ-----------
---------ILKEKFADASEEAVSVQRSMQET-VNKLHQKEE--QFNALSTELEKLR-EN
LTDMEAKFRERD-EREE--H-------LIKAKEKLENDIAEIMKMSGDNSSQLTKMNDEL
RLKERNVEE------LQLKLTKANEN-ANFLQKSIGEVTLQAEQSQQEAAKKHEEEKKEL
LRK--LLDLEKKV-EMSHNQCQDLKARFEEASCDMKAKHEAVLQNLHKMLSDTEERLKAA
QEKNSDLLQEMVELKKQADKAKAAQTAEDAMQIMEQMTKEKSETLASLEDTKQTNEKLQN
ELDTLKENNLKNVEELNKS------KELLTVENQKMEEFRKEIETLRQASAQKSQQLSAL
QEENVKLAEELGR--TR--DEVTGHQKL--EEERSVLNNQLLEMK-KRESKLIKDADEEK
AS-------LQKSISITSALLTEKDAELEKLRNEVTVLRGESASAKSLHSIVQSLESDKA
KLELQVKNL---ELQLKENRRQLGSSSGNTDTQA-----------------------EED
ERAQESQQMI-------DFLNSVIVDLQRK-NQDLKMKVEM---------MSEAALNGNG
DDLNNYDSDDQEKQSKKKPRLFCDIC-DCFDLHDT--EDCPTQA----QASEDPPHSTHH
GSRSEERPYCEICEVFGHWASHCNDDETF-------------------
>gi|118777920|ref|XP_308355.2|	Anopheles gambiae
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
--------------------------------MKTDFRGVA-------------------
------------DFAVVHYAGKVDYSATK------WLMKNMDPLNE---NVVSLLQASQD
PFVVQIWKDAE---------IVGMAQQALTDTQFGARTRKGMFRTVSHLYK---------
---------------------------------EQLAKLMDTLRNTNPNFVRCIIPNHEK
RAGKIDAPLVLDQLRCNGVLE-GIRICRQGFPN-RIPFQEFRQRYELLTPNVIPK-----
--GFMDGKRAC-EQMIKSLELDSNLYRIGQS---------KIFFRAGVLAHLEEER---D
YKITDLIVNFQAFCRG-------------------FLARRNYQKRLQQLNAIRIIQRNCA
AYLKLRN-----------------WQWWR------LYTKVKPLLEVTKQEEKLVQKEDEL
RQIRDKLENLSKN--SQEYE----KKYQQAMEEKTHLAEQL--QAEIELCAEAEEG----
--RA-------RLVARKQELEELMQDLESRI---------EEEEERVNALTSE-KKKLQI
NIQDLEE------------------QLEEEEAARQ-------------------------
----------------KLQLEKVQLDAKLKKMEEDVALIED-QNHKLVKEKKLLEER---
----ANDLSQTLAE-------------------EEEKAKHLAKLKVKHE---STIAELE-
ERLLKDHQQRQEADRSKRKIE-----TEVADLKEQ---------INERRMQIEEMQQQLV
KRE-EELAQTLVRIDEESAAKAAAQKTQRELESQLAE---IQED---LEAEKLARSK---
-----AEKQKRDLNE-------ELEALKNEL--LDSLDTTAAQQELRSKREQE-------
------------------------------------------VATLKKTLEDESANHEST
L----------MDMRHKHAQEISSINEQLENL-KKMKGGLEKSKQQLEAENADLATELRN
VNQSRQENDRRRKQA-------------ETQIAELQVKLADVDRVR--VELQDKVTKLQQ
ESENITQQLDEAE--LK---------ASAAIKSAGNLESQLTEAQQLLE-----------
---------EETRQKLALSSKLRQIESEKEAL-QEQLEEDEE--AKTNYEKKLAELN-FT
IQEMKKRSEEDS-DIAK--E-------LEESKKKMNKDIETLQRQIQELQAANDRLDKSK
KKIQSELED------ATIELDTQRTK-VLELEKK---------------QKNFDKVLAEE
KAI--SEQVAQER-DAAEREAREKETK---------------VLSLTRELDEAFEKIDEL
ETKRKGLQNELDELAN---------TQGTADKNVHELEKAKRALESQLAELKAQNEELED
DLQLTEDAKL---------------RLEVNMQALRAQFERDIQAKEEQSEEKRRGLVKAL
RDLEAELDEERKQ--RA--AAVAAKKKL--EGDLKDMEATLEMNN-KVKEDALKQAKKLQ
AQIKDAIRDAEEAKAAKEELAAISKESERKVKTLEADLMQLTEDLSSSERARRAAEGERD
ELLEEINSNSSKGSLMIDEKRRLEARIAALEEELEEEQS-NLELMVDRNRKAQLTIEQLT
TELATEKSNS-------QNNETLKCGLERL-NKELKAKLSE-QETALRTKLKAATAASEA
KNLNLEKQLENETKERLAVQKANRKLEKRIKELTMNIEDERRHADQYKEQIEKANNRMKT
LKRNLDEAEEEIQKEKTLKRKAQRECEDMLESHEALSREVNALKSKLR
>gi|157119504|ref|XP_001659410.	Aedes aegypti
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
----------------------------------------------SMCYLLDDVRRDEK
LKDIANTITNVNRW--------SSPCIADSIPL-TVVGVSPDEKPTRDENTVPPQ-----
------------YSAKSTGQMRPQSLTIPSTA---------------------------P
AIVSAIVKKIPTGISSSTKSDLSKTHQKTISS---PKLKPSQTHERGDPDGDCGLDDAPA
NYLSKNSELRV---------------------------TIPSTEELINSKKGWLMKQDS-
RSSDWSKYWFSLR--GAALF----YYRDPVAEEKGVLDGVLDVNSITSITEVPVAR-NYG
FQLT-------TWDNRRIVLSTVTISNRNNW---------INVLKNAAGLPQT-KVTLNN
NNLGLNN------------------QNDENFKTPV-------------------------
-TPVTPITPKSMLFSSDEEYRTASEGGRRDSVGDWGSPVSP-SPPVPLSAIARTKDRLRT
SH-NRLHKRSRSSPPSSRRSTI-----------ESVQSEDLPLINPVQE-EVCMDKELQ-
LRLQAAEKELSILREETHERE-----ARMSDLLAT---------LERTEQELTRKRECEE
NRD-KLVSQLDASRANAQEIIDRITVELDNSRDTVKE---LEDR---LARGIEENES---
-----LYKKIREFGISSPAS--SLCSLNTKTGKMRRMDSFSDLTSLNEVDPNTLD-----
------------------------------------------KDMLADEYHELRARFEKA
V-----------SELKAMKRELKDSHKMYDDL-EISYATLKREIERHQKEQESQTRMMAD
RIQDMTNKYTNAEKQ--VRLLRQKL---VRNEKRRSLSLKGKESLTIQKELEEKVTELEH
KIDALEQGAKNES--IL----TSPKVSEHLMDRLKSLEGVVISVRDLVD-----------
------------QSMRQFQNLRSSRSRRS----VSPIADKKD--SFKFIERCLSEVSKLL
RDSCEHCVIQDCSIHARCAEIQIRIDSLIETAKSIQAQCDECDRLQITLHQLTDRHETDI
ASLRRQNEE------QNTEEYVELEKERDYLFEQ---------------IRKEKDHVKKL
EKQ--LEMLEAEHAQQVDNLHAAYREQ---------------QMANEIDSQKDKDDEDSL
RLKYQAEIEQLRALCE-----KGLAAMEA--SHKRIIHDLEEKHQHEIAQLIVEKEQALA
EETQATLAALDAMRKAHQN------EVQREVARFKQEFLKQFQKGGQSPTSVKE-KEQEL
EEVRQEILSLSEK--YS--MKCVETASL--EEKLRIASQQLKYSQ-QHIQQLDVRNKQLR
AH----------------FVSGDSTDSVSTPKASTTQSSHDDANGKKTSTDGSRHHSLST
VIKAAANNG---GSVASSHNSPSPGHCFDNSNKE-----FHSINNKKESHPRLKLCEGAK
LGVSAVFPSS-------TSTGLDSVNLTSSNNRTKVLNSKQLNMSLLSGGTARHSTSTAS
NISSPATTGLTIPTSNASPGSSSQKSCTSKTNNNNNDNECLTEL----KPAIKMSSPLPL
DEKDVEQIHRFELEI---------------------------------
>gi|74191775|dbj|BAE32843.1|	Mus musculus
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-----------------------------------MSAAKENPCRKFQANIFNKSKCQNC
FKPRESHLLNDEDLTQAEPIYGGWLLLAPDGTDF--------------------------
---------------------------------DNPVHRSRKWQR-RFFILYEHGLLRYA
LDEMPTTLPQGTI---------NMNQCTDVVDGEARTGQKFSLCILTPDKEHFIRAE---
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-TKEIISGWLEML----------------MVYPRTNKQNQK--KKRKVEPPTPQEPGPAK
MAVT-------SSSGGSSGSSSSIPSA-------------EKVPTTKSTLWQE-EMRAKD
QPDGTSL-----------------------------------------------------
------------------SPAQSPSQSQP--------PAAC-TPR---EPGLESKED---
----ESTISGDRVDGGRKVRVESGYFSLEKAKQDLRAEEQLPPLLSPPSPSTPHSRRPQ-
-----VIEKFEALDIEK---------------------------AEHMETNMLILTTPSS
DTR-QGRSERRAIPRKR-DFASEAPTAPLSDACPLSP-----------------------
---------------------------------HRRAKSLDRRSTESSMT----------
------------------------------------------PDLLNFKKGWLTKQYEDG
Q-------------WKKHWFVLADQSLRYYRD-SVAEEAADLDGEINLSTCYDVTEYPVQ
RNYGFQIHTKEGEFT--LSAMTSGIRRNWIQTIMKHVLPASAPDVT--SSLPEG-KNKST
SFETCSRSTEKQE--AE------PGEPDPEQKKSRARERRREGRSKTFD-----------
--------------WAEFRPIQQALAQERASAVGSSDSGDPG--CLEAEPGELERERARR
REER---------RKRF--G-------MLDTIDGPGMEDTALRMDIDRSPGLLGTPDLKT
QNVHVEIEQ----RWHQVETTPLREEKQVPIAPL---------------HLSLEDRSERL
STHELTSLLEKEL-EQSQKEASDLLEQ--------------------NRLLQDQLRVALG
REQSAREGYVLQATCE-----RGFAAMEE--THQKKIEDLQRQHQRELEKLREEKDRLLA
EETAATISAIEAMKNAHRE------EMERELEKS---QRSQISSINSDIEALRRQYLEEL
QSVQRELEVLSEQ--YS--QKCLENAHL--AQALEAERQALRQCQ-RENQELNAHNQELN
NR----------------------------------------------------------
-LAAEITRL---RTLLTGDGGGESTGLPLTQGKD-----------------AYELEVLLR
VKESEIQYLK-------QEISSLKDELQTA-LRDKKYASDKYKDIYTELSIAKAKADCDI
SRLKEQLKAATEALGEKSPEGTTVSGYDIMKSKSNPDFLKKDRSCVTRQLRNIRSKSLKE
GLTVQERLKLFESRDLKKD-----------------------------
