>gi|149410035|ref|XP_001509639.	Ornithorhynchus anatinus
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-----------------------------MVLSNGTVWP-SGKSTGNCP-------PGQK
GESI-------------------------------------RDSGALEEGVSSKLQKFKQ
KELW------------NGFTPLYMAAQ-ENHLEVVKFLLDNGASQSLATE----------
-----------------------RG----ETALHMAA-RAGQA--EVVRYLVQN------
-GAQVEAKAKDDQTPLHISARLGKAEIVQQLLQQGAS--------PDAATSSGYTPLHLS
----AREGHEDVASVLLEHGASLAITTKKGFT----PLHVAAKYGKIE-----VANLLLQ
KSASP---DAAGKSGLTPLHVAAHYDNQKVALLLL---------DQGASPHAAAKNGYTP
LHIAAKKNQMDIATTLLEYGADANAVTRQGIASVHLAA---------------QEG----
HVDMVSLLLTRNANVNLSNKS--GLTPLHLAAQE------DRVNVAEVLVNQGAVVDSQT
-------KMGYTPLH--VGC------------HYGNIKIVNFLLQHFAKVNAKTKNGYTP
LHQAAQQGHTHIINVLLQNHAA-------PNELTVNGNTALAIA--RRLGYISVVDTLKV
VTEET---MTTITVTEKHKMNVPETMNEVLDMSDDEVRKANAPEMLSDGEYMSDVEEGED
AMTGDTDKYLGPQDLKELGDDSLPAEG-YMGFSLGARSASLRSFSSDRSYT-LNRSSYAR
---DSMMIEELLVPTKDP-----HLTFTREFDSD-------------SLRHYSWAADTLD
NV-NLVSSPIHSG---------FLVSFMVDARGGAMRGSRHHGMRII-------------
-----------IPPRKCTAPTRITCR----LVKRHKLAHPPPMVEGEGLASRLV---EMG
PAGAQFLGPVIVEIPHFGSMRGKERE-LIVLRSEN-GETWKEHQYDSKQEDLNELLN---
--------------GMDEELDSPEEL-GKKRICRIITKDF------------PQYFAVVS
RIKQESN-----------QIG-----------PEGGLLS------------------STT
VPLVQASFP-----------EGALT-KRIRVGLQAQPVPDEIVKKILGNKATFS------
--PIVTVEPRR----RKFHKPITMTIPVPPPSGEGTTNGFKGEITPSLRLLCSITGGT--
SPAQ----WEDITGTTPLTFIKDSVSFTTNVSARFWLADCHQVLETVGLATQLYRELICV
PYMAKFVVFAKTNDPVESSLRCFCMTDDKVDKTLEQQENFEEVARSKDIEVLEGKPIYVD
CYGNLAPLTKGGQQLVFNFYAFKENRLPFSIK---IRDSSQEPCGRLSFLKEPKTTKGLS
QAAV-------------------C----NLNITLPAHKKTEKTDRRQSFASLALRKRYSY
LTEPGMSPQSPCERTDIRMAIVADHLGLSWTELARELNFSVDEINQIRVENPNSLIAQSF
MLLKKWVTRDGKNATTDALTSVLTKINRIDIVTLLEGPIFDYGNISGTRSFADENNGFHD
TVDGYATLQTEMETPTGLHNTPPTPFQQDDFFSDISSIESPVRTPSRLSDGLVTSQGNMN
FTTEGPPVVKAEDTSLEDSKLDFLMPVARVYEASERDEKCLVEDVNLRKYPQYIGCLSGE
PKDGNHLKPKGIEKSRKV---GVSFEQLERGKSGVDEEMTEEKFKSLFEDIHLEEGMEAE
EMTEEKVQAILKHVQQAEQEMSSITGWQNEASSDNTESPPPLGCKMI-------------
------GGILERLDDSPDQCRESITSYLKG------EVGKFEA---NGNHSEGTPEGKTK
SHVTDSQNDVGKQKDRET------------------------------------------
------------------------------------------------------------
---------LKPKTQGPIRVEEQTLSLAAYQKSVEEMGKPATEEPKTSVPVSGKKMNRTS
PGDGKPRLTL------------------------------------------------QG
EEGAGISDHKVKSPGATLSRMAGCCSK------------VNDPYLLLLLLPRRSPLRAFI
SLFRLCSPRSKYDKTHF
>gi|18079216|ref|NP_065815.1|	Homo sapiens
-----------------------------------------MGKEQELVQAVKAEDVGTA
QRLLQRP--------RP-------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
----------------------------------------------GKA-----KLLGST
KKINVNFQDPDGFSALHHAALNGNTELISLLLEAQAAVD-IKDNKGMRPLHYAA--WQGR
KEPMKLVLKAG---SAVNIP---------------------SDEGHIPLHLAAQHGHYDV
SEMLLQHQSNPCMVDNSGKTPLDLACE-FGRVGVVQLLLSSNMCAALLEP----------
---------------RPGDATDPNG----TSPLHLAA-KNGHI--DIIRLLLQA------
-GIDINRQTKSG-TALHEAALCGKTEVVRLLLDSGIN--------AHVRNTYSQTALDIV
HQFTTSQASREIKQLLREASAALQVRATKDYCNNYDLTSLNVKAGDIITVLEQHPDGRWK
GCIHD---NRTGNDRVGYFPSSLGEAIVKRA-GSR----------AGTEPSLPQGSSSSG
PSAP--PEEIWVLRKP--FAGGDRSGSISGMAGGRGSG--------GHALHAGSEG----
VKLLATVLSQKSVSESGPGDS--PAKPPEGSA--------GVARSQPPVAHAGQVYGEQP
-------PKKLEPAS--EGK------------SSEAVSQWLTAFQLQLYAPNFISAGYD-
-LPTISRMTPEDLTAIGVTKPG-------HRKKIAAEISGLSIP--DWLPEHKPANLAVW
--------LSMIGLAQYYKVLVDNGYENI-DFITD----------------ITWEDLQEI
GITKLGHQKKLMLAVRKLAELQKAEYAKYEGGPLRRKAPQSLEVMAIES---PPPPEPTP
---ADCQSPKMTTFQDSELSDELQAAMTGPAEVG------PTTEKPSSHLPPTPRATTRQ
DS-SLGGRARHMS--------SSQELLGDGPPGPSSPMSRSQEYLLDEGPAPGTPPREAR
PGRHGHSIKRASVPPVPGKPRQVLP------PGTSH-FTPPQTPTKTRPGSPQA---LGG
PHGPAPATAKVKPTPQLLPPTER--P----MSPRS-LPQSPTHRG--FAYVLPQ------
--------------PVEGEVGPAAPG-PAPPPVP----------------------TAVP
TLCLPPE-----------ADAEPGR-------PKKRAHSLNRYAASDSEPE------RDE
LLVPAAAGP-----------YATVQ-RRVGRSHSVRAPAGA--DKNVNRSQSFA-VRPRK
KGPPPPPPKRS----SSALAS--ANLADEPVPDAEP-----EDGLLGVRAQCRRAS----
DLAG----SVDTGSAGSVKSIAAMLELSS-----------------------IGGGGRAA
RRPPEGHPTPRPASPEPGRV-ATVLASVKHKEAIGPGGEVVN----RRRTLSG------P
VTGLLATARRGPGE------SADP---GPFVE---DGTGRQRPRGPSKG-EAGVEGPPLA
K----------------------V----EASATLKRRIRAKQNQQENVKFILTESDTVKR
RPKAKEREAGPE------------------------------------------------
--------------------------PPPPLSVYHNGTGTVRRRPASEQAGPPELPPPPP
PAEPPP---------TDLAHLPPLPPPEGEARKP----AKPPVSPKPVLTQPVPKL----
---QGSPTPT------------------------------------SKKVPLPGPGSPEV
KRAHGT-PPP-VSPKPPP---PPTAPKPVKAV----------A------------GLPSG
SAGPSP--------APSPARQPPAA---LAKPP---GTPPSLGASPA-------------
------------KPPSPGAPALHVPAKPPR------AAAAAAA---AAAAPPAPPEG---
------------------------------------------------------------
------------------------------------------------------------
---------ASPGDSARQKLEETSACLAAALQAVEEKI----------------------
----------------------------------------------------------RQ
EDAQGPRDSAAEKSTGSILDDIGSMFD-----------------------DLADQLDAML
E----------------
>gi|7385113|gb|AAF61702.1|AF222	Bos taurus
---------------------------------MHFPGFGRADAATSFLRAARSGNLDKA
LDHLRNGVDINTCNQNGLNGLHLASKEGHVKMVVELLHKEIILETTTKKGNTALHIAALA
GQDEVVRELVNYGANVNAQSQKGFTPLYMAAQENHLEVVKFLLENGANQNVATEDGFTPL
AVALQQGHENVVAHLINYGTKGKVRLPALHIAARNDDTRTAAVLLQNDPNPDVLSK----
----TGFTPLHIAAHYENLNVAQLLLNRGASVNFTPQNGITPLHIASRRGNVIMVRLLLD
RGAQIETRTKDELTPLHCAARNGHLRISEILLDHGAPIQ-AKTKNGLSPIHMAA--QGDH
LDCVRLLLQYN---AEIDDI---------------------TLDHLTPLHVAAHCGHHRV
AKVLLDKGAKPNSRALNGFTPLHIACK-KNHIRVMELLLKMGASIDAVTESGLTPLHVAS
FMGHPPIVKSLLQREASPNVSNVKV----ETPLHMAA-RAGHT--EVAKYLLQN------
-KAKVNAKAKDDQTPLHCAARIGHTNMVKLLLENNAN--------PNLATTAGHTPLHIA
----AREGHVETALALLEKEASQTCMTKKGFT----PLHVAAKYGKVR-----MAELLLE
HDAHP---NAAGKSGLTPLHVAVHHNHLDVV-RLL----LP----RGGSPHSPALNGYTP
LHIAAKQNQLEVARSLLQYGGSANAESVQGVTPLHLAA---------------QEG----
HAEMVALLLSKQANGNLGNKS--GLTPLHLVAQE------GHIPVADVLIKHGVTVDATT
-------RMGYTPLH--VAS------------HYGNIKLVKFLLQHKADVNAKTKLGYSP
LHQAAQQGHTDIVTLLLKHGAS-------PNEVSSNGTTPLAIA--KRLGYISVTDVLKV
VTDE----TTVQLITDKHRMSFPETVDEILDVSED-------------------------
-----------------EGEDLGPRAERPDARDVDEEKELLDFVPKLDQV--VESPAIPR
---IPCVTPETVVIRADE-----PDQVSKEYDED-------------SLIPSSPATETSD
NI-SPVASPVHTG---------FLVSFMVDARGGSMRGSRHNGLRVV-------------
-----------VPPRTCAAPTRITCR----LVKPQKLPTPPPLAEEEGLASRVI---ALG
PTGVQFLSPVIVEIPHFASQGRGDRE-LVVLRSEN-GSVWKEHKNRYGESYLDQILN---
--------------GMDEELGSLEEL-EKKRVCRIVTTDF------------PLYFVIMS
RLYQDYD-----------TIG-----------PEGGSLT------------------SKL
VPLVQATFP-----------ENAVT-KRVKLALQAQPVPDELVTKLLGNQATFS------
--PIVTVEPRR-------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-----------------
>gi|73959509|ref|XP_853631.1|	Canis familiaris
-----------------------------------------MEMDTE-------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------ELLGST
KKINVNFQDPDGFSALHHAALNGNTELIALLLEAQAAVD-IKDNKGMRPLHYAA--WQGR
KEPMKLVLKAG---SAVNIP---------------------SDEGHIPLHLAAQHGHYDV
SEMLLQHQSNPCMVDNSGKTPLDLACE-FGRVGVVQLLLSSNMCAALLEP----------
---------------RPGDTTDPNG----TSPLHLAA-KNGHI--DIIRLLLQA------
-GIDINRQTKSG-TALHEAALCGKTEVVRLLLDNGIN--------AHVRNTYSQTALDIV
HQFTTSQASKEIKQLLREASAALQVRATKDYCNNYDLTSLNVKAGDIITVLEQHPDGRWK
GCIHD---NRTGHDRVGYFPSSLGEAIVKRA-GSR----------AGAEESPPQAGSSSG
PSAP--PEEIWVLRKP--FAGGDRSGSLSGAAGARSGG--------GHALHAGSEG----
VKLLATVLSQKSVSESSLGDS--PVKPPEGST--------GAARSQPPAAHAGQVYGEQP
-------PRKLEPAS--EGK------------SAEAVSQWLATFQLQLYASNFISAGYD-
-LPTISRMTPEDLTAIGVTKPG-------HRKKITAEISGLSIP--DWLPEHKPANLAVW
--------LSMIGLAQYYKVLVDNGYENI-DFITD----------------ITWEDLQEI
GITKLGHQKKLMLAVRKLAELQKAEYAKYEGGPLRRKAPQSLEVMAIES---PTPPEPAP
---ADCQSPKMTTFQDSELSGELQAAMTGPAEGAAAAAPTTTAEKPPNHLPPTPRASLRQ
EP-SLGGQARHMS--------SSQELLGEGPPGPGSPLSRSQEYLLDEGPASGTPPKETR
PSRHSHGVKRASVPPVPGKPRQVLP------PGASP-FTPPQTPTKAQPGSPQA---LGV
PHGPTPATAKVKPTPQLLPPTER--P----MSPRS-LPQSPTHRG--FAYVLPQ------
--------------PVESDAGPPPPT-AAPPP--------------------------VP
TLCLPPE-----------ADVEPGR-------PKKRAHSLNRYTASDSEPE------RDE
LLVPAAVGP-----------YATVQ-RRVGRSHSVRAPAGA--DKNVNRSQSFA-VRPRK
KGPPPPPPKRS----SSAMAS--ANLADESVPDAETEGAGAEDGQLGVRAQRRRAS----
DLAG----SVDTGSAGSVKSIAAMLELSS-----------------------IGGGGRAA
RRPPEGHPTPRPASPEPGRV-ATVLASVKHKEAIGPDGEVVN----RRRTLSG------P
VTGLLAAARRGPGD------SGGPADHGHVVE---DGATRQRSRGPAKG-EASAEGPSLA
R----------------------V----EASATLKRRIRAKQSQQENVKFILTESDTVKR
RPKAKEREAGPE------------------------------------------------
--------------------------PPPPLSVYQNGTGTVRRRPASEQTGPPELPPPPP
PAEPPPP--------TDLLHLPPLPPPDTDTRKP----AKPPVSPKPVLAQPVPKI----
---QGSPTPA------------------------------------SKKVPLPGPGSPEV
KRAHGT-PPP-VSPKPPP---PPTAPKPAKAA----------A------------GLQSG
SASPSP--------APSPARQPPAA---LAKPA---STRPSLSASTA-------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
---KPPPSSAEEKSTGSILDDIGSMFD-----------------------DLADQLDAML
E----------------
>gi|149057782|gb|EDM09025.1|	Rattus norvegicus
----------------------------MAERPRRSGSDPAADAATSFLRAARSGNLDKA
LDHLRNGVDINTCNQNGLNGLHLASKEGHVKMVVELLHKEIILETTTK------------
----------------------------------------------------VRDGFTPL
AVALQQGHENVVAHLINYGTKGKVRLPALHIAARNDDTRTAAVLLQNDPNPDVLSK----
----TGFTPLHIAAHYENLNVAQLLLNRGASVNFTPQNGITPLHIASRRGNVIMVRLLLD
RGAQIETRTKDELTPLHCAARNGHVRISEILLDHGAPIQ-AKTKNGLSPIHMAA--QGDH
LDCVRLLLQYN---AEIDDI---------------------TLDHLTPLHVAAHCGHHRV
AKVLLDKGAKPNSRALNGFTPLHIACK-KNHIRVMELLLKTGASIDAVTE----------
-----------------------KV----ETPLHMAA-RAGHT--EVAKYLLQN------
-KAKANAKAKDDQTPLHCAARIGHTSMVKLLLENDAS--------PNLATTAGHTPLHTA
----AREGHVDTALALLEKEASQACMTKKGFT----PLHVAAKYGKVR-----LAELLLE
HDAHP---NAAGKNGLTPLHVAVHHNNLDIVQLLL---------PRGGSPHSPAWNGYTP
LHIAAKQNQIEVARSLLQYGGSANAESVQGVTPLHLAA---------------QEG----
HTEMVALLLSKQANGNLGNKS--GLTPLHLVAQE------GHVPVADVLIKHGVTVDATT
-------RMGYTPLH--VAS------------HYGNIKLVKFLLQHQADVNAKTKLGYSP
LHQAAQQGHTDIVTLLLKNGAS-------PNEVSSNGTTPLAIA--KRLGYISVTDVLKV
VTDE----TSVVLVSDKHRMSYPETVDEILDVSED-------------------EGTAHI
SLTGD--------------ELVGSKAERRDSRDVGEEKELLDFVPKLDQV--VESPAIPR
---IPCVTPETVVIRSED-----QEQASKEYDED-------------SLIPSSPATETSD
NI-SPVASPVHTG---------FLVSFMVDARGGSMRGSRHNGLRVV-------------
-----------IPPRTCAAPTRITCR----LVKPQKLSTPPPLAEEEGLASRII---ALG
PTGAQFLSPVIVEIPHFASHGRGDRE-LVVLRSEN-GSVWKEHKSRYGESYLDQILN---
--------------GMDEELGSLEEL-EKKRVCRIITTDF------------PLYFVIMS
RLCQDYD-----------TIG-----------PEGGSLR------------------SKL
VPLVQATFP-----------ENAVT-KKVKLALQAQPVPDELVTKLLGNQATFS------
--PIVTVEPRR----RKFHRPIGLRIPLPPSWTDNPRDSGEGD-TTSLRLLCSVIGGT--
DQAQ----WEDITGTTKLVYANECANFTTNVSARFWLSDCPRTAEAVHFATLLYKELTAV
PYMAKFVIFAKMNDPREGRLRCYCMTDDKVDKTLEQHENFVEVARSRDIEVLEGMPLFAE
LSGNLVPVKKAAQQRSFHFQSFRENRLAIPVK---VRDSSREPGGFLSFLRKPMKYEDAQ
HIL--------------------C----HLNVTMPPCTKGSGAE-DRRRTLTPLTLRYSI
LSESRLGFTSDTDRVEMKMAVIREHLGLSWA-----------------------------
---------------VENLYTALRNIDRSEIVNMLEGSGRQSRNLKPDRRHGDREYSLSP
SQVNGYSSLQDELLSPASLHYALPSPLCADQYWN----EVAVIDAIPLAATEHDTMLEMS
D--MQVWSSGLTPSL-------------------------------VTAEDSSLECSKAE
DSDAIP-EWK-LEGAHSE---DTQGPELGSQDLVEDDTVDSDAT-----------NGLAD
LLGQQR--------VHARITDSPSVRQVLDRSQARTVDWYKQGSAAS-------------
----------YPQEAAQSSWQEEVTQGPQSFQRRITTIQGPEP---GTLQEYEQVVVSTR
EHVQRGPPES--------------------------------------------------
------------------------------------------------------------
---------DSPKAGKDPSLWASESAFSQEVQGDELQNIPG-------------------
----------------------------------------------------------EQ
VTEEQFTDEQGNIVTKKIIRKVVRQVDSSGAIDTQQHEEVELRGSGLQPDLIEGRKGAQI
VKRASLKRGKQ------
>gi|126309887|ref|XP_001378289.	Monodelphis domestica
-----------------------------------------MGKEQELLEAARTGHLPAV
EKLLSGKRLSSGFGGGS-------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
---------------------------GGSGGGSGGSSGSSGGGGLGSSSHPLSSLLSIW
RGPNVNCVDSTGYTPLHHAALNGHKDVVEVLLRNDALTN-VADCKGCYPLHLAA--WKGD
AQIVRLLIHQGPSHTKVNEQNALEIKELKKYGPFDPYINAKNNDNETALHCAAQYGHTEV
VKVLLEELTDPTMRNNKFETPLDLAAL-YGRLEVVKMLLNAHPNLLSCNT----------
-----------------------KK----HTPLHLAA-RNGHK--AVVCVLLDA------
-GMDSNYQTEKG-SALHEAALFGKTDVVQILLAAGID--------VNIKDNRGLTALDTV
REL-PSQKSQQIAAFIEEHMTGK----------------RSTKEGDR--LLRTQPS----
------------------FVPSMDSTALKSQ-GDV-----E----KAVNDLIMDFDMNSQ
EEVP--YEALYNAISS---------HSLDSMTSGKSSD---------------RES----
V---------------------------------------TKEAETAVVKASGVRPRERP
-------P----------------------------------------------------
-----------------PPAKP-------PPEEEEEEDAEMELC--PHISSEVPV-----
---------------------------------------------------MRSRSQGSA
SKEEDEHPYELLLTAETKKLVPLEGKIKEQRRSSSSRSQDSAEGLD------GQVPE---
-------------------------QFSGLLHGS------------------SPVCEISE
DP-FQLISSVSQG----------------GSEGSSRQGTSHEAAMQLED-----------
--------------------------------------APLHTPGSIRPSLPDQNKKLGY
SAGLPTNHSQSDPETLMHEISQH--P----GGAEE-AGDW--------------------
----------------SGTRSWAPPT-NRPKA----------------------------
--------------------------------ELKLSRSLSKS--------------DSD
LLTCSP---------------TEDT-TMGSRSESLSNCSIG--KKRLEKSPSFA------
-----SEWDEI----EKIMSSIGEGIDFSQEQQKISGSRMLEQ-----------------
SVGE----WLESI--GLQQYESKLLL----------------------------NGFDDV
HFL------------------GSNVMEDQDLREIGISDPQ-H----RRKLL--------Q
AARSLPKVKPL------------------------GCDGNAQPSVPS--WLDSLGLQDYI
QSFL-------------------S----SGYSSIDTVKNLWELELVNVLKVHLLGHRKRI
IASLADRPYEEPPQ----------------------------------------------
-------------------------KPPRFSQLRCQDLLSQTSSPLSQNDSC--------
---------------TGRSADLLLPPGDTGKRRH----DSCQDMAARGRVERFQT-----
---QEDPREA------------------------------------KLTLRPPSLAAPYA
PVQ----SWQ-HQPEKLI---FESCGYEANYLG---------S------------MLIKD
LRGTES--------TQDACAKMRKS----TEQM---KKIPTIILSIT-------------
-----YKGVKFIDASNKNIIAEHEIRNISC------AAQDPED---LCTFAYITKDLQTS
HHYCHVFST---------------------------------------------------
------------------------------------------------------------
---------VDVNLTYEIILTLGQAFEVAYQLALQAQK---------------ARPSGAS
SA--------------------------------------------------------ET
IETKASKPVPKPRVGMRKSALEPSDMDQDTQSHASVSWVVDPKPD--SKRSLSTKYETTI
F----------------
>gi|91080953|ref|XP_974604.1|	Tribolium castaneum
-----------------------------------------MGKDQELLEAARKGNVAVV
EKIL--------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
----------------------------------------------GQRAKRSGPLASLR
RGPGANVQDSSGYSALHHAALNGHREIVKLLLDHDASTN-IVDVKGSSPLHLAA--WSGN
VDIVKLLL-SGPSICNVNLT---------------------TQDDETALHCAAQYGHTAV
VSLLLEHACDPGIRNCRGETALDLAAQ-YGRLETVELLVRTDPSLIQCLK----------
--------------RAAPDTVYPH------TPLHLAS-RNGHK--AVVEVLLRA------
-GFSVNMRTKSG-TALHEAALCGKVEVVRTLLEHGVN--------TAIRDSHNYTVMDLL
SQFNTAQASQEIMGILKRKEVRKNETGARLFC-----------------------LGHKK
GLTIV---DSDGESISHPFPP-LPSTDSDIG-SPY----------ENVRPSSKNARSSTT
DPSPGTSPQRWDLRHA-RPPEGFEDRRVSGVSGISMRN----------------------
TKPYQSLPLKKRDSS--------DLSPLDGIT--------FKFKEQFSLRKSSTTSTDTY
-------HTACECRNSDSSR------------ESDNSLYQIPCVPKQFMDTSVHSEDLN-
-YLCTSRESDQISLSSTASSSG-------YPRRPDSGGVPLYIPMNNVRGGHSPSSNKVS
PTPPKKPPRRNLSVSPTHLQPMSMSVDGVTNSAYE------------------YLFLAHS
GTRSQGNLNDVEHDARR--------ERLSHGRSMDQYVEMNVFNIALDEDE-ERPKELHR
-----GKSEDLDCRKKYE-----PVAITSMYENM-------------IIKQQNPRRKLRR
NP-EVYEEYDFTK----------KEEPVASSSAPETTFVSSAFIMIGD------------
-----------EESKNCNYP-----------MSPTH-YKQPPTPDHPPPSALQA------
---ESLIYEKIRPLSQEYKRQSK--D----METET-EEEFLLICD---------------
--------------ESSGSLSSSVSL-SDRSVDNII----------------EEYHSDAP
FAGLIKG-----------STRVLENISSNT--PAERPKTL-----------------KKL
KRVYDGSST-----------DAAKS-DNEKSSSSEKEYENKENKDRVSALSPFD------
---EQEEWAKI----QEIMASFGTGIVRESVFVAELEKEFQSR---LMTLSCSQNSLNAD
SIEK----WLQTL--GMQDYVGLFMS----------------------------NGFDDV
NFL------------------VSKVIEDCDLSEMGITSELE-----RQIIL--------D
AVKQLPLKIHNQS----------------------FNNNNNNEQNSVKSWLSRIHLDQYF
DTFN-------------------K----HLYHDMERIKRIWDVELSAVLDIDKIGHRKRI
LASVSSGEH---------------------------------------------------
-------------------------IISGPKLEEINADLNLLKNQELKS-----------
---------------PSAHSTGTIRHRHKKSRPA----PPPPIKIDK-------------
----------------------------------------------ESEKKKPAEMFVGG
NNSIKS-QWR-HQPILLI---TGVVMYSANYLGS---------------------TNIIE
FKGTES--------TKKSIQKVVKN---KERPS------EEITLSIS-------------
-----YRGVKFINPITKNTICEHEIRNINC------ACQDSDN---QSYFAYITKDG--D
SFYCHVF-----------------------------------------------------
------------------------------------------------------------
---------ESTSSAIEIILTLGQAFELAYQMAVRDQVTSKG------------------
----------------------------------------------------------KT
KSAVSPGAVSSHSRDFKDLKTNGHPLK-----------------MKPLTLSIAADPDKTE
E----------------
>gi|156555698|ref|XP_001602889.	Nasonia vitripennis
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------MLSCLF
IVIAV------------YAEVQELMEVVKLLLQHEASTN-IIDAKGSSPLHLAA--WSGN
SEIVRLILSQGPSVPNVNLT---------------------TKDNETALHCAAQYGHTEV
VAQLLQYGCDPSIRNSRGESALDLAAQ-YGS-----------------------------
---------------------------------------------ACVEVLLAA------
-GVYVNTRTSAG-TAMHEAALCGKMEVVRTLLDRGVD--------LAIKDSRHNTVLDLL
GQF-PAHVTQDITAVIKRHRSSSGIESDADSEN--------------------LPPI---
----P---VHQGNDSLGSPEDELYGEPMDGAWRHL---QLT----EDSDPSSVFDSVFMS
MSDT--LNSINTLASSDQTPEDRPLNTNLITTPSRDTP------------RGSDSG----
LYQTPPVPRALAEGYNSEDQL--SLTLPAGCY--------GGRESDQLSVSSSSSIGGPS
-------PRERRCPTGESSS------------SGPGIYLPMAPLSSSLHSPASSSKVSNG
GLPSTLQPTP--------PKKP-------PRRNLSVSPTHLQ------------------
--------TQMSLSADCH--VGPSNYEYL--FLAR-----------------SGGAHSQI
DLDQIQARREQLRHVTRSVDQYVDMKSRFDQHQQQDGKGSDVEPVAI-------------
---MGERQMRMTNPRRKLRRHAYERSAYENYEMD-----------SSPGADKSPCSDGHE
RT-FVSNAFLTLK--------SSQESLLDDSKEPAGE-----------------------
-----------ATDKRLKRVQMMLP------TSPTH-YVQPPTPDHPPPSALQA------
---EKSIHERIRPLSQVYKRRSR--D----METETEEELLQFPAGG--------------
--------------SLDASSGSLSSVSLSDKSMSTDNV--------------EEYFGDVP
FAGLLKG-----------SVS-----------AAERPRTLRRLR---------------N
VYSPATGGMGTGA-------DVAGE-QRLEHHHQSHHHHQQQQQQHQQESRSSG----DE
LGSGNQRDDKT----LSIMSP--FDEQEEWGQDLGNHGLNSDTGSPSVVT----------
LVGQ----WLSKL--NLADYESLFLNY----------------------------GFDDL
EFI------------------VSGVLDDSDLKDMGITSEQD-----RASIL--------N
AASMLNNRV--------------------------EKRPAGNPNQSVDEWLKSIHLESYA
ELFR-------------------R----HLYTDMDRVRRVWEVELAAVLEIKKPAHRKRI
LASVSGGSSTHSVASHVRN-----------------------------------------
---------------GNGPNLEDLNKDLNTLKSNIQQLKDEIREKHPDTVQGNGLPTPTT
TSAATTGLSTATVAGTNASTTGTL--KHRKNRPA----PPPPQKPSSHNGAVQASE----
----------------------------------------------NLEIRGPSELLFGV
PSTLKT-QWR-HQPKDLV---TGSVTYVANYLG---------S------------TVVKE
LRGTES--------TKKSIQKLKK----VCRDP---RGTPDITLSIS-------------
-----YRGVRFLNTLTDEPICEHEIRNIHC------ACQDADD---LTHFAYITKDHASR
THFCHVFCVP--------------------------------------------------
------------------------------------------------------------
---------TMVNMATEIILTLGQAFEVAYQIAIKDKLGGHAIRSQSSSQLASLASSAMN
SATKVASSPSRESSHSEQRNNESNNHYQTSTNPRTKPRSKSITNPFLNSRSGLSLPQQQQ
SSCRVPSPNKTSSSSGTTTTPVAMKLLATHGRSHSVNDIKINGNQLKLAPAPMDDISIGV
KDMKAGSRAPIALSEEL
>gi|118099945|ref|XP_420128.2|	Gallus gallus
-----------------------------------------MGREQDLIQAVKNGDIPGV
QKLVAKI--------KA-------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
----------------------------------------------SKS-----KLLGSA
KRLNVNYQDADGFSALHHAALGGSLDLISLLLEAQATVD-IKDSNGMRPLHYAA--WQGR
VEPVRVLLRAA---ASVNMA---------------------SLDGQIPLHLSAQYGHYEV
SEMLLQHQSNPCLINKAKKTPLDLACE-FGRLKVAQLLLNSHLCVALLEG----------
---------------QSKDVTDPNY----TTPLHLAA-KNGHK--EIIRQLLKA------
-GIEINKQTKTG-TALHEAALYGKTEVVRLLLEGGVD--------VNIRNTYNQTALDIV
NQFTTSHASKDIKQLLREASGILKVRALKDFWNLHDPTALNVRAGDIITVLEQHPDGRWK
GHIHD---IQKGTDRVGYFPPSIAEVISKRI-GMILPRMAPTHQHQGTPGALMALPDCSP
PRLQHLPDECPQQAAPGIPPSYGHLTLTWTAPGPDSSA--------GDRNSVGSEGSIGS
IRSAGSGQSTEGTNGQNTNIVIENTRPLPSTGDDLQQHLLGSEPLNEQINSTTGPPGYQT
-------PSSCTPGDKVFSHQFLRPEQLLEGKDAEAIYNWLSEFQLESYTVNFLSAGYD-
-VPTISRMTPEDLTAIGVTKPG-------HRKKISTEIGQLSIA--EWLPNYIPADLMDW
--------LSAIGLPQYHKKLVNNGYDSI-TIVTD----------------LTWEDLQEI
GINKLGHQKKIMLAVKKLRDLRKS-LSQAEATLTRHKVPGALHIVTIESL--ENGECQSP
------NTPKMTTFQDSELSYELQTAMSNSCHET-------------LSIKNSQGMSQSQ
E--SIGVRSRGSGHSQDNVLSWHLSSPSQESLGSGESSSSSSGQS---------------
-----------CMPPHSKESLASLPR----QPSPEP-YGKLTSPEGLNSFTNGS---GGS
PLKERNLPEGTDQYAQLTAQKGAGPVGTLMVTPST-PPQTPSMATAPYVFMYPHV-----
--------------SLKSPRAPSSQGAEQPKTLAHSYPSFSSGQKNSLQTSAPKAFSYLH
SQCSPAELLEAATAPNAWQTGEQHKGGESSK-NKKRSHSLNRYALSDGEHE------EEE
GMPTSTLGS-----------YATLT-RRPGRSQMPRACLQT--EAKVTRSQSFA-IRAKR
KGPPPPPPKRL----SSVSSTLTTEVDSEQLPDPERQSSVPQDAAD--------------
MGAS----PGDSGCSRTVRSLVATLEETP-----------------------GLNPPKPL
LAPKPLHVAQDSLSKAAVDDRSHNSCDPSSTALSDSGQDPFDSSKPRRRTLSE------P
STPMTEAVQGRQEDACS------------------DTEEEAKPEVSSSSQNSSSECIPFA
E---------------------------EGNLTIKQRPKPAGHPKADAAVQDTEPSSQPA
ESTCSDGKELAVSAVT--------------------------------------------
-------------------------RELPMLEFNLTESDTVKRRPRFKEREP--------
---------------LQAVLKAFSMAGQAEVGAS----SAPQYAQAQAVSILGP------
----------------------------------------------TTQGPALQTGLAGD
AFDDDSVEFR-IAEIEKS---ILSLEKGIN-------------------------KAPSP
VKAPSPTELLGTAVVRMPAPDVPAKHTSVASTKLVFSGPKTIYQQVL-------------
--------QPSRHTIAPWAATEVVPNVIGS------LAGPSPLTLEASGKVFVKPLA---
------------------------------------------------------------
------------------------------------------------------------
---------SAPGAALVQQQLEHTSIIT--LQAAEKKI----------------------
----------------------------------------------------------TV
EEVQSPP--RATHSAKNILEDISNMFD-----------------------DLADQLDAML
D----------------
>gi|148680321|gb|EDL12268.1|	Mus musculus
-----------------------------------------KGALTSIPAIRMDSMLSTW
QPRKAMWASCRSCWEEGPPWI-----------------------LPPRKGNTALHIASLA
GQAEVVKVLVKEGANINAQSQNGFTPLYMAAQENHIDVVKYLLENGANQSTATEDGFTPL
AVALQQGHNQAVAILLENDTKGKVRLPALHIAARKDDTKSAALLLQNDHNADVQSKMMVN
RTTESGFTPLHIAAHYGNVNVATLLLNRGAAVDFTARNGITPLHVASKRGNTNMVKLLLD
RGGQIDAKTRDGLTPLHCAARSGHDQVVELLLERKAPLL-ARTKNGLSPLHMAA--QGDH
VECVKHLLQYK---APVDDV---------------------TLDYLTALHVAAHCGHYRV
TKLLLDKRANPNARALNGFTPLHIACK-KNRIKVMELLVKYGASIQAITESGLTPIHVAA
FMGHLNIVLLLLQNGASPDVTNIRG----ETALHMAA-RAGQV--EVVRCLLRN------
-GALVDARAREEQTPLHIASRLGKTEIVQLLLQHMAH--------PDAATTNGYTPLHIS
----AREGQVDVASVLLEAGAAHSLATKKGFT----PLHVAAKYGSLD-----VAKLLLQ
RRAAA---DSAGKN------------------------------------------GYTP
LHIAAKKNQMQIASTLLNYGAETNTVTKQGVTPLHLAS---------------QEG----
HTDMVTLLLDKGANIHMSTKS--GLTSLHLAAQE------DKVNVADILTKHGADRDAYT
-------KLGYTPLI--VAC------------HYGNVKMVNFLLKQGANVNAKTKNGYTP
LHQAAQQGHTHIINVLLQHGAK-------PNATTANGNTALAIA--KRLGYISVVDTLKV
VTEEVT--TTTTTITEKHKLNVPETMTEVLDVSDE---------------------EGDD
TVTGDGGEYLRPEDLKELGDDSLPSSQFLDGMNYLRYSLEGGRSDSLRSFSSDRSHTLSH
---ASYLRDSAMIDDTVVIPSHQVSALAKEAERN--------------SYRLSWGTENLD
NV-ALSSSPIHSG---------FLVSFMVDARGGAMRGCRHNGLRII-------------
-----------IPPRKCTAPTRVTCR----LVKRHRLATMPPMVEGEGLASRLI---EVG
PSGAQFLGPVIVEIPHFAALRGKERE-LVVLRSEN-GDSWKEHFCDYTEDELNEILN---
--------------GMDEVLDSPEDL-EKKRICRIITRDF------------PQYFAVVS
RIKQDSN-----------LIG-----------PEGGVLS------------------STV
VSQVQAVFP-----------EGALT-KRIRVGLQAQPMHSELVKKILGNKATFS------
--PIVTLEPRR----RKFHKPITMTIPVPKASSDVMLNGFGGD-APTLRLLCSITGGT--
TPAQ----WEDITGTTPLTFVNECVSFTTNVSARFWLIDCRQIQESVAFASQVYREIICV
PYMAKFVVFAKSHDPIEARLRCFCMTDDKVDKTLEQQENFSEVARSRDVEVLEGKPIYVD
CFGNLVPLTKSGQHHIFSFFAFKENRLPLFVK---VRDTTQEPCGRLSFMKEPKSTRGLV
HQAI-------------------C----NLNITLPIYAKESESDQEPEEEIGMTSEKNDE
TES---------------------------------------------------------
-------------------------TETSVLKSHLVNEVPVLASPDLLSEVSEMK-----
---------------QDLIKMTAILTTDVSDKAG--------------------------
----------------------------------------------SLKVKELAKAGEEE
PGE----PFEIVERVKED---LEKVNAILRS------------------------GTCMR
DEGRAR--------SSQSERELEEEWVIVSDE----EIQEAKQHAPV-------------
--------------EIDEHPCIEVRVDRETKAKVEKDSTGLVNYLTDDLNSYTSPHE---
------------------------------------------------------------
------------------------------------------------------------
---------KKPHTAPEKSGETSQASAVGKSSESNKGK----------------------
----------------------------------------------------------AT
SAEEKQSAQKQLKPGLAIKKPVRRK-----------------------------------
-----------------
>gi|72146807|ref|XP_791879.1|	Strongylocentrotus purpuratus
-----------------------------------MTSCMLQGKRFYCREWAFQKLVHGL
DNRQASRTCGTLIMGGP-------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
----------------------------------------------GSGKSALCSEIVWP
NSAGKQRSLTKRMLAYHFCEAHNRESLSVSKFILGLVNM-ITRSTLIHGYD-----EKLR
DPRVQAVLEPAACERNPDEA---------------------FKNGVLVPLCSLNPPSRNC
--FILVDSVDEAYPVLEGDSPAGSRTI-AELLANHHELFPPWLCLLCSAR----------
-------------RQSKTVTRMFTG----FRKLSLDDLRKSHVVRDVQQYILRRLDHEEA
IRTQLSKDTAEMLNQLHIKSN-GCIMYLEKVLDGVADGFISLQDITEIPGTLNGLYLWLC
QRLFQKKHFTKIRPVLGVMLAAQCPLTELELY-------ACAKTRNFALTREEFQDRLKM
MCKIL---VRSKDNRILLFHHSFSEWLLDVKYCTQKYMCSL----TEGHTMLALRYTCSA
PDLT--PSQVQDFARNLIQAGLSPPLDSSSLALWLIWA--------GTPLYDCLASQSPK
DKQVTQLLVSAGARVVDIDRN--SLILQDAL---------DKQESLHSLINSGASINQVD
-------SNGRSLLA--NAA------------YSGNLEVVQSLLIYGADVGVTDRTGQTA
LGLAARHGHVEAVALLLSHDAE-------VDHVDHDGWTPLRSA--AWAGHTDVVTTLLS
KGAV----VDCSDHNEKRTALRAAAWGGHADIVKT------------------LIDNGAN
VNQADHEGRTALIAAAYMGHSAIAEYLVNNGAEINHEDFDGRTALSVAAMSIAVNQGHTD
---VVTLLIEKGAAVDHRDHEGMSPLLVAAYEGH----QTVVELLLEGGADVDHTDNNNR
TALIVAASMGHPS--------IVRTLLYWGAAVDTIDGEGRTVLSIA-------------
-----------ASQGTCDIVRMLLERGLDEMHKDNHGWTPLHMCAYEGHQDVCLAILEQG
PHVTVDIADRDGRTPLVLAAQEGHME----------GVKVLLLHGANVCHISHD------
--------------GRTALRAAASEG-----------------------------HQDLV
HLFLEHG-----------AEINYR--------DAEGRSTMYMLALENKLP-------MAQ
SFLANGADT-----------ELCDTEGRTALHVASWQGHSEMVSLILQNNANPNAVDKER
RSVLQSAAWQGHVSVAKVLLERGADINHTCNQGASALCIAAQEGHVDVVKALLQYGANPN
HADQHGRTPMKVALKGGHEEVSKLLEDYG-----------------------VQNPLSPP
SSRASSKRSGSSLSSSNSDNKPSVLTNGALLQGSSPSNSPDSTYDKRKSCTSN------P
STKSSSNLTNSTNNSCLHLSGMRENRSTATS----FTEQVQQHMVSHKRAPSPRTCSPDP
ALMRNGTPTK-------------I----TPTSSFQTIPENITTAHSSEQLQGTPKHGSRR
HPSGASSAASRR------------------------------------------------
-------------------------AQSPAHASSRSSSPSMHQQREQLSATPSEASSQPS
PRHSPR---------RQSSSSAPSSPTNSDERKP---PPTPQRVRKSSNPLPNGSSQHIM
VHNVKSASPS------------------------------------PTRRAVPRTSSQQK
PPKMGNGHFQNHQDVPSPWHKQQSHMHLIQQHQECQQSLYRASSLGSINSQELNTSFQNP
SNGSHP--------YPPQDYSPRLSRKQMNDSNGSCHYCGQNQPSPT-------------
----HGAKHSFQQSVIMQQNEMKITSSHHR------SNSQPVNLTPDQMKAFARKA----
------------------------------------------------------------
------------------------------------------------------------
---------SLPNSFNQINIQRLMGAQNNRVPGSPEPRAR--------------------
----------------------------------------------------------RS
GICTNPKFQRKANTGTGISTSQGMLNQ----------SGIITNGNGLSPLEIKQAAKIGF
EGSSRNGYKKETPL---
>gi|47216277|emb|CAG05973.1|	Tetraodon nigroviridis
-----------------------------------------MGKDQELLQAVKTEDLLTV
QKLLQRP--------RP-------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
----------------------------------------------GKASSLLCIMLHSM
EIWSSSLCCWSHRLPLTSGTRKGCGRCTT------------QPGRGRRTHEDAAQIWFLG
QWPIR--------------------------------------RGADPAPPGGAHGHYDV
SEMLLQHQSNPCIVDNAGKTPLDLACE-FGRVGVVQLLLSSNMCAALLEP----------
---------------KKGDTTDPNG----TSPLHLAA-KNGHI--DIIRLLIQA------
-GIDINRQTKAG-TALHEAALCGKTDVVRLLLESGIN--------ATVRNTYSQTALDIV
YQFTATQASREIKQLLRDASAALQVRALKDYCNNYDLTSLNIKAGDVITVLEQHPDGRWK
GCIHD---NRTGNDRVGYFPSTMVEVISKRT-GCR-----G----TEASPHCSPTPSCGP
HGGS--NEEIWVLRKPVAGGDRSSLGSSSSVNSVRSSGSGQSAGSAPHILHAQAEG----
VKLLATVLSQSAKAKEHLLEQ--TKSMDQPA---------GSNSSSRTSSQSGCPLHEAP
PYEATAARKGEGPGEGKLASSVLRMLGCSHDPSSEAVVQWLSDFQLQVYAPNFLGAGYD-
-LPTISRMTPEDLTAIGITKPG-------HRKKLTSEINKVSVS--EWLPEHKPANLGEW
--------LSAIGLSQYHQVLVQNGYENI-EFITD----------------ITWEDLQEI
GITKLGHQKKLMLAVKRLAEMQRSSEGRSSFKKKPPPITQQQEVMSMD----SPPPDVVP
SFSAEVMSPKMSTFQDSELSSELQNAMSQPGHEI-----------------------SKA
QR-ARSFSKDHDE-------------AMTGGGGPPKKEARTMRQQSSQGSSSSSR-----
-----------GSVSSQGKRHSHSHS----QPAPP--YTPPHTPTKTRTSSSSS-----T
SSAQSIASPQSKPKPAHFGQGER--P----QSPRSHSNQSPTHRGALCTQ----------
--------------PQPQQFHPQHQTHPQPHPQPQVTEVK------------DNQQSQVP
LLCLPPE-----------GEMPEGDGAESSALQKKRAHSLNRYAVSDGEGDEPVGGGRNG
GKAPAAGGQGSAASKAEGEKYATVT-HRVSRSHSVRNQDK---SASRNQTQSFA-LRQKK
KGPPPPPPKRS----SSAISSSNSNLADANAQPQTHATAG-GLLDVPYHQQRRASDLGVS
VETA----PVETNSAGSVRSIAAMLEMSS-----------------------IGGGAKGM
ALQ------------------KNFLQVGKTREAIGLDGEVVN----RRRTISG------P
VTELVEAARREQPA------PSAP-----PPP---SAESRSPPASSSPAASSPPHPPP--
----------------------------EANPTLKRRPRSTKSQPNGADFTLQESSTVKR
RPKSRDKEPDGFAELAAAN-----------------------------------------
---------------GEPAGAAP--PNTTQPAAFQNGTATVKRRPTSDASVTEQPEPQPQ
PQYQSPPQAAAARRRNSVEQAAPGSTDGGPARKP-----KPPVSPKPIVAQIKR------
---QGGPQTPPHPAS-------------------------------NKSIPLPGPGTPGS
PVEGKKIPPP-VSPKPAP---PPTAPKPAKLVH---------S------------MTSPS
CHSTTT--------APAPVRQHSLASRQSSSPP---GLPPTNIPSPP-------------
----------NAKPLSPSPQSPHTPQTPPT------PQTPATP---SPTPPPVKPPRSSI
GGVSVDSGTP--------------------------------------------------
--------------------------------------------------------GGGV
TTPTPTTTDFSVDFLVQQKLEETSASLAAALQAVEDKI----------------------
------------------------------------------------------------
--LHQEDSVAEQKTTVSILDDIGSMFD-----------------------DLADQLDAML
E----------------
>gi|148226138|ref|NP_001086927.	Xenopus laevis
-----------------------------------------MGRENELIQAVKSGDVGAV
QKFLAKF--------RT-------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
----------------------------------------------PKS-----KLLGST
KRLNVNHQDADGFSALHHAALSGNSELLLLLLEMQASVD-IKDGNGMRPLHYAA--WQGQ
PEPVRLLLRAS---ASVNAA---------------------SHDGQIPLHLAAQYGHYEV
SETLLQHQSNPCHVNKGKKTPLDLACE-FGRVKVVQLLLNSHLCVSLLEG----------
---------------TSKDPTDPNF----TTPLHLAA-KNGHL--EVIRLLLKL------
-GIEINKVTKMG-TALHEAALCGKTEVVKLLIENGVD--------VNIRNTYNQTALDIV
NQFTTTHASIDIKQLLREASGILKVRALKDFWNAHDPTALNIRAGDLITVLEQHPDGRWK
GHIHD---PQKGTDRVGFFPPSIVEVISKRL-GSTLSRNIT----VPSHQHLAKTVLTLP
IQHS--PGSQLGINPDTSVAGDRHSVGSESSVRSAGSG-------------QSCEG----
QQINTALLIENAQTMDFGSEN-------------------LQNCQTFPGPVSGHHLSTIL
-------PVEKNPGDYLQGK------------DAEQIFCWLRGFQMETYVGNFISAGYD-
-LPTIMRVTPEDLTAIGVTKPG-------HRKMISTEIGKLIVA--DGLPQQIPVDLWDW
--------LSQLGLPEYHKQLSENGYESL-STVTE----------------LTWEGLQEI
GIHRLGHQKKLLLGVKRLLDLQK---GYPIGGTLRRRILGSQDTVAVVE---PPENGDLP
------VTPKLLTFQGAELSQELQSALTRGNEQL--------------------------
------------------------------------------------------------
-----------CTGRRSFSQESISSR----SQGSGH-------SQESASSYPVL------
---PVHLQGVDLNLPERNHPEGTDQI----L-----QNHWV-------------------
--------------PNGCLIQPEPPA-PPPKPA---------------------------
--------------------------------LKKRSLSACRYALSDGEPE------EEE
EKKIATAGTGTLST------YATLT-RRPGRSCLTNGKP----EKKVQRSQSFA-VRARR
KGPPPPPPKRL----SSM------------------------------------------
SSAE----GQSPEGQSSVKTIAAQLKDIG-----------------------RGTGF---
---------------------SASTSKATDTEVLEGSGT-------RRRTVSESAAGLGG
RLSLPLTTKKDEEE--------------------------ERKEEPISSQHSSSESIPFA
E---------------------------EGNLTIKQRPKPPGAKLEQDATSELSPTQESQ
LQSAEAQRHLESSAV---------------------------------------------
-------------------------LAKPVTVVLAQARPQIAAKPQIGPKPDTGARAPPA
TSIP-----------KNEEHDFNLTESDTVKRRP--------------------------
------------------------------------------------KVKEKEEESPKA
PLANNS--PS-LIPSQEP---LTQDTLIAKIADIDK-------------------RLLSL
GEVEDS--------VKKTGIDTRSTGVSISQTHLVISGPQQVLQKPS-------------
-----------RAVTGPLFPAGSILWDEES------EASSREQ-----------------
------------------------------------------------------------
------------------------------------------------------------
---------TCIPQQSISNSDKGPPVFTSSLQNTE-------------------------
----------------------------------------------------------EL
QDTRGKSCRETVQLTKNILDDISTMFD-----------------------DLAEQLEAML
D----------------
>gi|109127251|ref|XP_001084114.	Macaca mulatta
---------------------------------MATLACFGVLRVAGEEAAVRVRSLRGA
SPLARLPLLLIHTGCGP-------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
----------------------------------------------GLAVGVLHELLGST
KKINVNFQDPDGFSALHHAALNGNTELISLLLEAQAAVD-IKDNKGMRPLHYAA--WQGR
KEPMKLVLKAG---SAVNIP---------------------SDEGHIPLHLAAQHGHYDV
SEMLLQHQSNPCMVDNSGKTPLDLACE-FGRVGVVQLLLSSNMCAALLEP----------
---------------RPGDATDPNG----TSPLHLAA-KNGHI--DIIRLLLQA------
-GIDINRQTKSG-TALHEAALCGKTEVVRLLLDSGIN--------AHVRNTYSQTALDIV
HQFTTSQASREIKQLLREASAALQVRATKDYCNNYDLTSLNVKAGDIITVLEQHPDGRWK
GCIHD---NRTGNDRVGYFPSSLGEAIVKRA-GSR----------AGTEPSLPQGSSSLG
PSAP--PEEIWVLRKP--FTGGDRSGSISGVAGSRGSG--------GHTLHAGSEG----
IKLLATVLSQKSVSESSPGDS--PAKPPEGSA--------GAARSQPPVAHTGQIYGEQP
-------PKKLEPAS--EGK------------SAEAVSQWLTAFQLQLYAPNFINAGYD-
-LPTISRMTPEDLTAIGVTKPG-------HRKKIAAEISGLSIP--DWLPEHKPANLAVW
--------LSMIGLAQYYKVLVDNGYENI-DFITD----------------ITWEDLQEI
GITKLGHQKKLMLAVRKLAELQKAEYAKYEGGPLRRKAPQSLEVMAIES---PPPPEPTP
---ADCQSPKMTTFQDSELSDELQAAMTGPAEVG------TTAEKPSSHLPPTPRATTRQ
ES-SLSGRARHMS--------SSQELLGDGPPGPSSPMSRSQEYLLDEGPAPGTPPKEAR
PGRHGHSVKRASVPPVPGKPRQVLP------PGTSH-FTPPQTPTKTRPGSPQA---LGG
PHGPAPATAKVKPTPQLLPPTER--P----MSPRS-LPQSPTHRG--FAYVLPQ------
--------------PVEGEVGPAAPG-PAPPPVP----------------------TAVP
TLCLPPE-----------ADAEPGR-------PKKRAHSLNRYAASDSEPE------RDE
LLVPTAAGP-----------YATVQ-RRVGRSHSVRAPAGA--DKNVNRSQSFA-VRPRK
KGPPPPPPKRS----SSALAS--ANLADEPVPDAEP-----EDGLLGVRAQCRRAS----
DLAG----SVDTGSAGSVKSIAAMLELSS-----------------------IGGGGRAA
RRPPEGHPTPRPASPEPGRV-ATVLASVKHKEAIGPGGEVVN----RRRTLSG------P
VTGLLATARRGPGE------SADP---GLFVE---DGTGRQRPRGPSKG-EAGVEGPPLA
R----------------------V----EASATLKRRIRAKQNQQENVKFILTESDTVKR
RPKAKEREAGPE------------------------------------------------
--------------------------PPPPLSVYQNGTGTVRRRPASEQAGPPELPPPPP
PAEPPP---------TDLAHLPPLPPPEGEARKP----AKPPVSPKPVLTQPMPKI----
---QGSPTPT------------------------------------SKKVPLPGPGSPEV
KRAHGT-PPP-VSPKPPP---PPTAPKPAKVAA----------------------GLPSG
SAGPSP--------APSPARQPPAA---LAKPP---GTPPSLGTSPV-------------
------------KPPSPGAPALHVPAKPPR------AAAAAAA------APPAPTEG---
------------------------------------------------------------
------------------------------------------------------------
---------ASPGDSARQKLEETSACLAAALQAVEEKI----------------------
----------------------------------------------------------RQ
EDAQGPRDSAAEKSTGSILDDIGSMFD-----------------------DLADQLDAML
E----------------
>gi|24649312|ref|NP_651143.1|	Drosophila melanogaster
-----------------------------------------MGKDQEFLEAARNGNISHI
EKVL--------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
----------------------------------------------TQKAKRAGPLASLR
RGTGVNVQDSGGYSALHHACLNGHEDIVRLLLAHEASPN-LPDSRGSSPLHLAA--WAGE
TEIVRLLLTHPYRPASANLQ---------------------TIEQETPLHCAAQHGHTGA
LALLLHHDADPNMRNSRGETPLDLAAQ-YGRLQAVQMLIRAHPELIAHLG----------
------TEALERGTPSPSSPASPSRAIFPHTCLHLAS-RNGHK--SVVEVLLSA------
-GVSVNLLTPSG-TALHEAALCGKENVVRTLLKAGIN--------LNATDNEGRTALDIL
REF-PPHVTKHIVAVINNFRNQMDTDEGDEVI------------------YRQHSGPPNS
GRGQNKHHSQQQPPLSNHYHFNSNNHLLNHS-------------------HSMQQSGYSK
QRLS----------------------------AGNGGP---------------YNG----
GKSLDSALQPEDRFYQDLNAH----SPLHSQNEMG-----GGYSVSPSSSLSSFEPASVS
-------PRSRCSTGG-LGQ----------------------PMHMSTFAPA--------
----------------GPPKKP-------PRRNLSVSPTHAGPG--QQFSYSSPSSQSQS
Q-------SHGHGQNQVRRQPASESPYSH-QSHGS----------------VGGMSFDET
QLRERQRNDRLYASARQSTRSAIAGGMSLSSSNDMLDRQCSSSELNSETSV-PNSSGDSP
----ATNSMKRPIPAPRSSTTKLSKELLKSAESA-------------TLKSYNPNRKLKR
NRNSSGANGAAKS-----------------------------------------------
----------NGGDENCEAKQQIPS-------SPTH-YKQPPTPDHPPPSSSQA------
---ERTIHERIRPLSQEYKRRSA--L----LQLQA-AQQLMIETGSSPSKLLPTLSTPGY
DYDDTVTVVPRCPAPSSGSLSSSISC--SDHSLSHSTDYV------------EEFVSDVP
FAGL----------------------------LKGASQQLKEQP-------------EVK
LKIQEESKP-----------QQTL--PRVRPPIPTKPAIPE---------KKFA------
-KPPTTPTNQS----LEANGNSSSDVVIKPPRSPSKSPSKTSNKSPVKSPGK--------
SPAK----SPGSGHSAARNSINLLSPFNA----------EEARKKISEIIENFGSGILNT
SITPTHDIELDFEDMEVPNERRELATRLRAAGLLHLERILFENGYDNYKFVNNVFEE--P
DIPLLHIPERDAPKLLRFVQSLPPAEFQPQVPVKTQQENKQMGVATLQQWLNTIALPEYL
EFFKLVFTINTPMIATSKVFLFTLSCSKHLYNTIESVCGVWDVELQTVLEINKLGHRRRI
LQSLAYIRQMRDSDSK--------------------------------------------
-------------------------SQKTPLGENNETNQLTTNGNGTAREAPPRLP----
---------------ANPVHHRNSITGYRKSRPA----PPPPAPPARKTA----------
----------------------------------------------ALQIRAPSELLLGL
PANLRTTEWR-HSAQTLL---NEHINYEVQYLGS---------------------TVVKE
LRGTES--------TKKSIQKLKTS---ADGEV---KSGSPLSLAIC-------------
-----HRGVEFKDVNSKRTICEHEIQNINC------ACQDSED---LRHFAYITKEQ--D
LHYCHVFLV---------------------------------------------------
------------------------------------------------------------
---------ESTDLASEIILTLGQAFEVAYQLALRDGI----------------------
------------------------------------------------------------
------------TTTPELLLDNGMLQG----------------------------EYCGG
K----------------
>gi|114619918|ref|XP_001139366.	Pan troglodytes
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-----------------------------------------------------MVRLLLD
RGAQIETKTKDELTPLHCAARNGHVRISEILLDHGAPIQ-AKTKNGLSPIHMAA--QGDH
LDCVRLLLQYD---AEIDDI---------------------TLDHLTPLHVAAHCGHHRV
AKVLLDKGAKPNSRALNGFTPLHIACK-KNHVRVMELLLKTGASIDAVTESGLTPLHVAS
FMGHLPIVKNLLQRGASPNVSNVKV----ETPLHMAA-RAGHT--EVAKYLLQN------
-KAKVNAKAKDDQTPLHCAARIGHTNMVKLLLENNAN--------PNLATTAGHTPLHIA
----AREGHVETVLALLEKEASQACMTKKGFT----PLHVAAKYGKVR-----VAELLLE
RDAHP---NAAGKNGLTPLHVAVHHNNLDIV-KLL----LP----RGGSPHSPAWNGYTP
LHIAAKQNQVEVARSLLQYGGSANAESVQGVTPLHLAA---------------QEG----
HAEMVALLLSKQANGNLGNKS--GLTPLHLVAQE------GHVPVADVLIKHGVMVDATT
-------RMGYTPLH--VAS------------HYGNIKLVKFLLQHQADVNAKTKLGYSP
LHQAAQQGHTDIVTLLLKNGAS-------PNEVSSDGTTPLAIA--KRLGYISVTDVLKV
V-TDE---TSFVLVSDKHRMSFPETVDEILDVSED---------------------EGND
SLTGSTHSKALSQGLEPRGGMEVGGSLCF---LLDLRTALSDRAVGSRGST-FSTWHLVS
---SGKILPSL------------HALASKEYDED-------------SLIPSSPATETSD
NI-SPVASPVHTGPTCICPTPRFLVSFMVDARGGSMRGSRHNGLRVV-------------
-----------IPPRTCAAPTRITCR----LVKPQKLSTPPPLAEEEGLASRII---ALG
PTGAQFLSPVIVEIPHFASHGRGDRE-LVVLRSEN-GSVWKEHRSRYGESYLDQILN---
--------------GMDEELGSLEEL-EKKRVCRIITTDF------------PLYFVIMS
RLCQDYD-----------TIG-----------PEGGSLK------------------SKL
VPLVQATFP-----------ENAVT-KRVKLALQAQPVPDELVTKLLGNQATFS------
--PIVTVEPRR----RKFHRPIGLRIPLPPSWTDNPRDSGEGD-TTSLRLLCSVIGGT--
DQAQ----WEDITGTTKLVYANECANFTTNVSARFWLSDCPRTAEAVNFATLLYKELTAV
PYMAKFVIFAKMNDPREGRLRCYCMTDDKVDKTLEQHENFVEVARSRDIEVLEGMSLFAE
LSGNLVPVKKAAQQRSFHFQSFRENRLAMPVK---VRDSSREPGGSLSFLRKAMKYEDTQ
HIL--------------------C----HLNITMPPCAKGSGAE-DRRRTPTPLALRYSI
LSESTPGSLSGTEQAEMKMAVISEHLGLSWAELARELQFSVEDINRIRVENPNSLLEQSV
ALLNLWVIREGQNANMENLYTALQSIDRGEIVNMLEGSGRQSRNLKPDRRHTDRDYSLSP
SQMNGYSSLQDELLSPASLGCALSSPLRADQYWN----EVAVLDAIPLAATEHDTMLEMS
D--MQVWSAGLTPSL-------------------------------VTAEDSSLECSKAE
DSDATGHEWK-LEGALSE---EPRGPELGSLELVEDDTVDSDATNGLIDLLEQEEGQRSE
EKLPGS---KRQDDATGAGQDSENEVSLVSGHQ---RGQARITHSPTVSQVTERSQDRLQ
DWDADGSIVSYLQDAAQGSWQEEVTQGPHSFQGTSTTTEGLEP---GGSQEYEKVLVSVS
EHTWTEQPEA--------------------------------------------------
------------------------------------------------ESSQADR-----
---------DRRQQGQEEQVQEAKNTFTQVVQGNEFQN---------------------I
PG--------------------------------------------------------EQ
VTEEQFTDEQGNIVTKKIIRKVVRQIDLSSADAAQEHEEVTVEGPLEDPSELEVDIDSFM
KHSKDHTSTPNP-----
>gi|125802956|ref|XP_682906.2|	Danio rerio
-----------------------------------------MGKEQELLQAVKTEDLVTV
QRLLQRP--------KQ-------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
----------------------------------------------GKA-----KLLGAA
KKVNVNFQDTDGLSALHHAALNGNVELISLLLESQSVVD-IKDQKGMRPLHYAA--WQGK
CEPMKMLLKAG---SSVNSQ---------------------SDEGQIPLHLSSQHGHYEG
SEMLLQHQSNPCLRDHAGKTPLDLACE-FGRVTVVQLLLNSNMCAAMLEP----------
---------------KP---SDPNG----ISPLHLAA-KNGHI--EIIKLLIQA------
-GIDINRQTKSG-TALHEAALCGKTEAVRLLLDSGIS--------AGVRNTYCQTALDIV
NQFTTTQASKEIKQMLRDASAAMQVRALKDYCNNYDLTSLNIKAGDIITVLEQHSDGRWK
GCIHD---NRTGNDRVGYFPSNMVE-VIKRA-GSR------------GSVSSPHGSPTLS
GQQSGANEEIWVLRKPLAGGSVGSMGSTGSLSGRSSAS-----GQSSNAMHAQAEG----
VKLLATVLSQSAKAKEHLMDQSQSVSDPNSGTAMSSPQRPQSVSAVPRQQRKKPFVDPLL
-------QRKDEASA--ESK------------SSEAVVEWLTSAQLQFYTTNFLTAGYD-
-LQTISRMTPEDLTAIGVTKPG-------HRKKMLSEISKMNIP--DWIPQEKPSSLAEW
--------LSAIGLNQYYQTLVQNGYDNM-DFISD----------------ITLEDLKEI
GFTKLGHQKKLMLAIKRLSESPEAESLSKESQ--LEESTDAKQPLESST---EPDVNSVP
-----------------------SARIRKRAEGR-------------SEGRPEGRADGRS
EG---RSSPRHST-----------------------------------------------
---QGRGIQRANAPPPLKKPSSI--------DSPTP--TPPHTPTKGRTSSSSS------
------------NSPSHIPSS----P----LKTQS------RTRG---------------
--------------PCDSPRSHAHAR-------------------------------TVP
VLCLPPE-----------GETEESNGQTPS--QPRRGQSINT---------------DAD
LPMPDSSVK-----------YATLGGHKTTSSSSTRTSGESLDINSVNRSQSFATARPRR
RTRPPTPPKRS----CSSIST--GNLTDEAVADDARLSENRANNLLLNVTYRERRRSD--
CGIA----SEKTSSGGSVRDIAAMLEMSN-----------------------LGNSGKGS
---------------------GSGYTQVSQNVLRQNREVLNSDADSRRRTISEFYDSQKQ
SADVQEAEMRQDTA------HHKPEPRETHLL---KQAPEPRPRSMITHLEGGVSSLPQE
EWSR-------------------M----DATATLRRPRPPHHTDGEH--FNLTETSTIKR
RPKAL-------------------------------------------------------
-------------------------AQPQSNGTDGDGPENFRRRPVSEACVGDGGRD---
---------------EELHHDGFGSLP----RQI----LKPPVSPKPAMALRK-------
---FDPPTP-------------------------------------TRRVPLPGPEGQHS
PVEVRKIPPP-VSPKPSP---PPTLPKPVKIKPI---------------------HTIGT
PGSPQP-----DVVSPFSASFSPVSIEQLEHPP---QTLSPVTPKPM-------------
-----EGNMLSPRPATSPAQSPQTPQTPQT------PQTPSTP---GSGSAPVKPPRSSM
AGLSVDIPSPLEVDVPGLDVQKRLRESDKQREDDDMRKQERVDEVGFAKMERTGLIQLDP
LFQGEQGLISGSSVGSHLIEAGDGAGPVVMRRRKVGVARQTQVEGESQEGEGKTEMEGQG
LLKIAETGGSSCGDVMQLRLDETSASLAAALEVVEEKIKKD-------------------
----------------------------------------------------------DR
YMSGSPRDEGMEVSTVNILDDIGSMFD-----------------------DLADQLDAML
D----------------
>gi|149742942|ref|XP_001495886.	Equus caballus
-----------------------------------------MGKDQELLEAARTGNVALV
EKLLSGRKGGILGG----------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
----------------------------------------------GSGPLPLSNLLSIW
RGPNVNCTDSSGYTALHHAALNGHKDIVLKLLQYEASTN-VADNKGYFPIHLAA--WKGD
VEIVKILIHHGPSHSRVNEQ---------------------NNENETALHCAAQYGHSEV
VAVLLEELTDPTIRNSKLETPLDLAAL-YGRLRVVKMIISAHPNLMSCNT----------
-----------------------RK----HTPLHLAA-RNGHK--AVVQVLLEA------
-GMDVSCQTEKG-SALHEAALFGKVDVVRVLLETGID--------ANIKDSLGRTVLDIL
KEH-PSQKSLQIAALLQEYLEGMG-----------------------------RSTVLEE
HVQED---TTPETHISSPVESPSQKTKSETVTGEL-------------------SKLLDE
IKLC--QEKDYSFEDLCHTISDHYLDNLSKISEEELGK-------------NGSQS----
VRTSSTINLSPGEVEEEDDDE--NTCGPSGLWEALTPCN-GCRNLGFPILAQESYPKKRN
------YTMEIVPSA-----------------SLDTFSSENENFLCDLTDTAVTKKPCSL
EIARAPSPRTDNASEVPITAPGT-----SNHRNSSTGPTPDCSP--PS-PDTALKNIVKV
IRPQPKQRTSIVSSLDFHRMNHNQEYFEI---------------------------NTST
GCTSFTSNPPVSPPTSSVGTTEVKNEGTGHTDDLSQQEDN------------DPPKEYDP
------------------------GQFAGLLHGS------------------SPACESPE
NPFHLYGKKDERE-----------------------------------------------
-----------EAQDEVSLASSPLPS----KKSPME-NNSEPSVKKIKPKVVSR------
----TIFHKKSNQLENHTIVGTRTSR----SGSRN-GDQWIVNTGGFV------------
--------------ERACTLGRIRSL-PKALI----------------------------
--------------------------------DMHLSKSVSKSD-------------SDL
IAYPSNEKT-----------------SRVNRSESSTAEHSS--KGNSERTPSFT------
-----SEWEEI----DKIMSSIDVGINSG----LKEINGEITRPRCPVQ-----------
TVGQ----WLESI--GLPQYENHLMA----------------------------NGFDNV
QFM------------------GSNVMEDQDLLEIGILNSGH-----RQRIL--------Q
AIQLLPKMRPIGHD------GYHP--------------------TSVAEWLDSIELGDYT
KAFL-------------------I----NGYTSMDLLKKIWEVELINVLKISLIGHRKRI
LASLGDRLHDDP------------------------------------------------
-------------------------PQKPPRSITL-------REPSGNHTPPQLSPSLSQ
STYTTGGSLDV----PHIIMQGDARRRRNENYFE----DIPRSKLERQMAQ---------
---TGDWGEP------------------------------------SITLRPPNEATAST
PVQ----YWQ-HHPEKLI---FQSCDYKAFYLG---------S------------MLIKE
LRGTES--------TQDACAKMRANCQKSTEQM---KKVPTIILSVS-------------
-----YKGVKFIDATNKNIIAEHEIRNISC------AAQDPED---LSTFAYITKDLKSN
HHYCHVFTA---------------------------------------------------
------------------------------------------------------------
---------FDVNLAYEIILTLGQAFEVAYQLALQARK------------------GGHS
ST--------------------------------------------------------LP
ESFENKPSKPIPKPRVSIRKSVDLLHA-------------SHTGQQPYGRHSEETKTILI
ELHYTYLIKHQ------
>gi|119916513|ref|XP_871198.2|	Bos taurus
-----------------------------------------MEVDNKK------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------ELLGST
KKINVNFQDPDGFSALHHAALNGNTELITLLLEAQAAVD-IKDNKGMRPLHYAA--WQGR
KEPMKLVLKAG---SAVNIP---------------------SDEGHIPLHLAAQHGHYDV
SEMLLQHQSNPCMVDNSGKTPLDLACE-FGRVGVVQLLLSSNMCTALLEP----------
---------------RPGDTTDPNG----TSPLHLAA-KNGHI--DIIRLLLQA------
-GIDINRQTKSG-TALHEAALCGKTEVVRLLLDNGIN--------AHVRNTYSQTALDIV
HQFTTSQASKEIKQLLREASAALQVRATKDYCNNYDLTSLNVKAGDIITVLEQHPDGRWK
GCIHD---NRTGNDRVGYFPSSLGEAIVKRA-GPR----------AGAEPSPPQGGSSAG
PTVP--PEEIWVLRKP--FAGGDRSGSLSSAAGGRSVG--------GHTLHAGSEG----
VKLLATVLSQKPVSDSSPGDS--PVKPPEGPA--------AATRAQPPAAHAGPGYGEQP
-------PKKLEAAS--EGK------------GAEAVSQWLATFQLQLYAPNFISAGYD-
-LPTISRMTPEDLTAIGVTKPG-------HRKKITAEISGLSLP--DWLPEHKPANLAVW
--------LSMIGLAQYYKVLVDNGYENI-DFITD----------------ITWEDLQEI
GITKLGHQKKLMLAVRKLAELQKAEYAKYEGGPLRRKAPHSLEVMAIES---PPPPELAP
------------------------------------------------------------
------------------------------------------------------------
--------------ADCQSPKMVLP------PGASH-FTPPQTPTKPRPSSPQA---LGG
PHGPAPATAKVKPTPQLLPPTER--P----MSPRS-LPQSPTHRG--FAYVLPQ------
--------------PVESEAGPAAPG-PAPAAVP----------------------TPVP
TLCLPPE-----------ADAEPGR-------PKKRAHSLNRYAASDSEPE------RDE
LLVPAAAGP-----------YATVQ-RRVGRSHSVRAPAGA--DKNVNRSQSFA-VRPRK
KGPPPPPPKRS----SSAMAS--ANLADEPAPDAETEGAGAEDGRLGVRAQRRRAS----
DLAG----SVDTGSAGSVKSIAAMLELSS-----------------------IGGGGRAA
RRPPEGHPMPHPASPEPGRV-ATVLASVKHKEAIGPDGEVVN----RRRTLSG------P
VTGLLATARRGSGE------PAGPADHGQLVE---EGAARQRPRGPAKG-EAGAEGPPLA
R----------------------V----EASATLKRRIRAKQSQQENVKFILTESDTVKR
RPKVKEREAGPE------------------------------------------------
-------------------------PPPPPLSVYQNGTGTVRRRPASEQAGPPELPPPPP
PAEPPP---------SDLMHLPPLPPPDSDARKL----AKPPVSPKPILAQPVPKI----
---QGSPTPA------------------------------------SKKVPLPGPSSPEV
KRAHGT-PPP-VSPKPPP---PPTAPKPAKAAA----------------------GLQSG
SSSPSP--------APSPARQQPAA---LAKPA---STPPALSASPA-------------
---------SPARPPSPGAPALHVPAKPPR----------AAA---AATGPPAAPDG---
------------------------------------------------------------
------------------------------------------------------------
---------ASPGDSARQKLEETSACLAAALQAVEEKI----------------------
----------------------------------------------------------RQ
EDAQGSRPSAAEKSTGSILDDIGSMFD-----------------------DLADQLDAML
E----------------
>gi|125773091|ref|XP_001357804.	Drosophila pseudoobscura
-----------------------------------------MGKDQEFLEAARNGNISHI
EKVL--------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
----------------------------------------------TQKAKRAGPLASLR
RGTGVNVQDSGGYSALHHACLNGHEDIVRLLLANDASPN-LPDSRGSSPLHLAA--WAGE
TDIVRLLLTHPYRPATANLQ---------------------TIEQETPLHCAAQHGHTGA
LALLLGHDADPNMRNSRGETPLDLAAQ-YGRLQAVQMLIRAHPELIAHLA----------
--------AMERGTRSPSSPASPSRTIFPHSCLHLAS-RNGHK--SVVEVLLAA------
-GVSVNLLTPSG-TALHEASLCGKENVVRTLLKAGID--------LSATDNEGRTALDIL
REF-PPHVTKHIVAVINNFRNQMDTDE--------------------------VDEVIYR
QHAGPPPLSGRGGQQMNHYHFNSNNHLLNHS-------------------HSMQQSVYSK
QRMS----------------------------AGNGGG--------------PYNG----
GKSLDSALQPEDRFYQDLNAH----SPLHSQNEMV-----GGYSVSPSSSLSSFEPASVS
-------PRSRCSTGGVGGQ----------------------PLQMSTFAPA--------
----------------GPPKKP-------PRRNLSVSPTHAGSG--QQFSYSSPC-----
--------SSQGQQQQNLRRPPPTDSPYSHQSHGS----------------VGGMSFDET
QLRERQRSDRLYASARQSTRSAIAGGVSLSSSNDMLDRQCSSSELNSETSV-PNSSGESP
----ATSSMKRPIPAPRSAATKLSKELLKSCESA-------------TLKSYNPNRKLKR
NRNSSANVASKSS-----------------------------------------------
---------GDAADENCEAKQQIPS-------SPTH-YKQPPTPDHPPPSSSQA------
---ERTIHERIRPLSQEYKRRSA--L----LQLQA-AQQLMIETGSSPSKLLPTLGTPGY
DYDDAVTVVPRCPAPSSGSLSSSISC-SSEHSLSHSTDYV------------EEFVSDVP
FAGLLKG-----------SVSQ----------PRELQPTV-----------------QVL
VQVPEEGKPQQQ--------QLQKPIPRVRPPLPTKPAVPE--RKFIKPPTTPTNQAQQQ
QQSPQTLEANG----NSAMDAAAAPLAPRRSPSKSPTKSAGKSPAKSPGSGHSAATRNSI
NLLS----PFNAE--EARKKISEIIEN-------------------------FGSGILNT
SITPTHDIELDFEDMEVPNERRELATRLRTAGLLHLERMLFENGYDSYKFVHNVFEE--P
DIPLLHIPERDAPKLLRFVQTLPPAEFQPQVPIKTQQENKQQGVATLQQWLHSIALPEYL
EFFKWHASPKGYLLKSIKSISYSK----HLYNTIESVCGVWDVELQTVLEINKLGHRRRI
LQSLAYIRQMRDSDSKA-------------------------------------------
-------------------------SLKTPLGENNETNQLTTNGNGNKEAVAARIP----
---------------PNPVQHRNSITGYRKSRPA----PPPPAPPAR-------------
---KAVPSTA------------------------------------PLHIRAPSELLLGL
PANLRTTEWR-HSAQTLL---NEHINYEVQYLGS---------------------TVVKE
LRGTES--------TKKSIQKLKAS---GEGEG---KSGSPLSLAIS-------------
-----HRGVEFIDVSSKRIICEHEIQNINC------ACQDSED---LRHFAYITKEQ--D
LHYCHVFQV---------------------------------------------------
------------------------------------------------------------
---------QSTDLASEIILTLGQAFEVAYQLALRDGI----------------------
------------------------------------------------------------
------------AATPALLLDNGMLLG----------------------------EYCGG
K----------------
