>gi|24650662|ref|NP_651571.2|	Drosophila melanogaster
------------------------------------------------------------
----------------------------------------------------------MC
LAAEPPQK--------------------------------QPNRSSTS-----PTFNAKY
R--------------------------RKCLLLL--------------------------
---------------------------------------TLLLFHGCFSGLHRAAAFNCT
A--HGGR-------------------CQNDGQCQE-DGQCL-------CADGWQGPECQ-
-----------------FCGGKVRMYHPMG--TI------------HDGWGNYSV---SV
KCSWLIDAR--HPHWNRRHNTNPSRTANIRIHLREFATE-CGWDHLYIYDGDSV------
-------------DSPLLAVFSGLMYRG----NFSIRRVP-QVIATSGTALVH--FFSDD
AYNMS-GFNLTYKMNSCPSDSDEVECSG---------------------HGKCRDGD---
----CI-------CDPMYRGEACNI-------AACPN----NC---FESKNQGHCRL-DQ
-------ERQISA-HGA---------------WSTVH---PKHSP--APAGSASHGAT-I
WRDTLHIVGGESYGRG--KLMSTYDFNGNVWETV--HPEDGSEVPDKRYGASTVMYGDK-
------------IFMYGGVVK------GH-GISNELWAFDVSARTWANISVRADPSCNAT
GGTTAMCGPLHVVGHTATLVP---------------------------------------
---VQEFNFASREW-------------RIVPTTGYVVKGGYGHSAAYDFLTEKVYVYG--
-GIVSESESS--QVLSSRLYA-YEPATRVWSLLSAA----PSARLLHTANFVNQG---LM
MVFGGNTHNDTSQSYG-------------------AKCYSQDLLVYDVYCDSWHYHPMP-
--GHLQADLARFGHSSV---------VFEESLYIYGGFN---------------------
GQLLNDMLRYQP--------GYCSYYTKQEKCTAARPGVKCIWDVQKMRCIAITQVQRSA
IYGRE--QYDYVAC------------------PSKSRLTLTSELLHDVHRCQELASCQSC
---------VSTAFGCTYCG----NGVC--SKERCRETTSMASVFFESST------QMAV
STASPPLNAKHLDSCPISEEYLVSSV-CDQL----HNC--------RACSANLA------
-------------CRWDSEH-------------------NRCKSYT--------------
--------------------------------------SYGGLALNR-------------
------------------------------------------------TQDEVACSPSCA
SLTN-----CQNCTED--------ECIWCQNEQRCVDRNAYTASFPYG-QCR--------
---EWTTFTAKCRSAPIQSTALAVGST--TALSSAQ---C---GYYNSCQMCLDDPAC--
GW--------CDNG-----SNTG--LGRCVVGGALAP-----------------YDDTEC
AL-KH---WFFT---SCP------------------------------------------
--------------------------------RCNCNGHSY----C-----NDQQHCEQP
CNNLTTGAHCEKCRTGY-WGNPIN-GGKCQRC--DCNG--QGVYCHP-------------
------------------DTGKCF-------------CTTKGIVGDHCEKC---------
--------------------------------------------------DSQNHYHGDP
L-K--GSCYYELTIDYQFTFNLSKKEDRHF----------TQINFRN-SPGKPEIDADFT
ITCS----------VPAKMDISVKR-----AGSPDM-------------------LILVG
VNCST--FRHRFPKTDYQFGHSP--------DDNSSLTTFYV-----------FVHDFQ-
-PPIWIQ-----------------------------------------IAFSQYPK-LNL
QQFFITFSSCFLLLL-LMAAVLWKIKQ----------------------KYDMFRRRQRL
FVEMEQMASRPFSQVLVDIENR--------------ESIDLSLTLEGIGHLS-KKRKKEC
PS----------------------------------------------------------
----------------------------PIALE-PCSGNRAAVLS--------LLVRLP-
--T----GGLSQAPSGQSAGLAVASA----------------L----------------V
TLGN----PRRPSIDQ---HPKEP-KSKRKQSQHPDS-------CT--------
>gi|110763256|ref|XP_397194.3|	Apis mellifera
------------------------------------------------------------
------------------------------------------MAEVVQMFLFLYKSKYRR
KGQCREVV--------------------------------RDQCGVIA-----VPWPILW
------------------------------------------------------------
---------------------------------------AALICWVVHVTAAASSSSSSL
T--TDTTCDTD---------------SCVNGDCV--NGTCV-------CHEGWQGSACQ-
-----------------FCGGKVKLTEPTG--NI------------HDGIGNYTA---DV
KCSWLIESS---------------PNSTIRMHVEQFATE-CGWDHMYIYDGDSV------
-------------EAPLLAVFSGLMHKD----GYHIRRVP-EVIARSGSALLH--FYSDV
AYNMS-GFNISYKINACPSRYSHIDCSG---------------------HGVCIDGV---
----CT-------CDATWTGEACEI-------QVCPN----NC---SHSHGQGECNR-ES
-------HHCDCV-HGFKENWIIIDR----GFWES-----VFYTD-FSPEGSASHCSI-V
WKDSLYIVGGESFHRA--KMIYVYDFNGNVWETP--H--VEGKVPQPRYAHSCILFGDK-
------------IFMYGGVLP------NS-TVTNEIWAFDVSAKVWENVTVHDN--SNKT
-----MRGPLKVAGHSATLVN-------------HGR------KEKMVVIFGYSPQY-GY
LNEIQEYYLGTREW-------------QIVDTIGFPVKGGYGHSSAYDALTNLIYVYG--
-GYVSESQTT--QVLTSRLYS-YDPNFRQWTLLTAA----PSARFFHTAVFISGG---LM
IVFGGNMHNDTQHSDG-------------------TRCYSADTIAYDVTCDSWHQFPMP-
---KEMTDLPRYGHSAT---------VFEKSMYIYGGFD---------------------
GQMLSDMTRYTP--------GNCEHLTNQNHCLNARTGVKCVWDKRENRCIQITKISRHV
LLNDDMHDGIYMRC------------------LDDTP---PRGMTSHKELCKLLTDCVAC
---------VQTSYNCIWCG-----KSC--SHEICRDN----------------------
ANAPPTKAISDLEQCDAHT-----AIKCLQL----HTC--------HACSSNPH------
-------------CIWS-----------------WSNGPDRCK-----------------
-------------------------------------PYSKAREVIV-------------
------------------------------------------------LQDS--CRSPCV
DYTS-----CKNCTES--------DCIWCQNEKRCVDKNAYPASFPYG-QCR--------
---EWTTVDSKCHPTET---------------GKEW---C---TFYSSCAACRSDPGC--
GW--------CDDG-----SGTG--KGLCLPGGARGP---------------STKSLDTC
SI-ER---WYFT---KCP------------------------------------------
--------------------------------TCQCNGHSK----C----LSNSSICIQP
CGNLTYGPHCDKCIPGY-YGNPLN-GATCQPC--FCNN--QGTQCTS-------------
------------------ETGKCF-------------CTTKGIIGDHCERC---------
--------------------------------------------------DVSSLYHGDP
TNK--GSCFYDLAIDYQFTFNLSKKEDRQY----------RAINFKN-SPPKPDIDAEFS
ITCS----------VLAKMNITVKR-----ANTPEM-------------------PVILG
ANCTTSMYKHRFIKDGYGFGS----------ENNNTLTTFYV-----------YVYDFQ-
-PPVWIQ-----------------------------------------ISFSQYSK-LNL
QQFFITFCTCFLALL-LVAAVLWKIKQ----------------------KYDMYRRRQRL
FVEMEQMASRAFSQVLVEIERR--------------DIDNSDSERSESELVNCRKKKKDA
PS----------------------------------------------------------
----------------------------PIALE-PCCGNRAAVLS--------LLVRLP-
--T----GGEPYTPAGQSAGLAVASA----------------L----------------V
TLGS----PRRPSQEL---TTKEPTKTRKSASQHPDST------CI--------
>gi|4454561|gb|AAD20947.1|	Mus musculus
------------------------------------------------------------
------------------------------------------MVAVAAAAATEARLRGST
TTTAAPAG--------------------------------RKGRQHRP-----CTATGAW
RPGP-----------------------RARLCLPRVLSRAL-------------------
----PPPPLLPLLFS----LLL-----------------LPLPREAEAAAVAAAVSGSAA
A--EAKECDRP---------------CVNGGRCNPGTGQCV-------CPTGWVGEQCQ-
-----------------HCGGRFRLTGSSG--FV------------TDGPGNYKY---KT
KCTWLIEGQ---------------PNRIMRLRFNHFATE-CSWDHLYVYDGDSI------
-------------YAPLIAAFSGLIVPE----RDGNETAP-EVTVTSGYALLH--FFSDA
AYNLT-GFNITYNFDMCPN-----NCSG---------------------RGECKSSNS-S
SAVECE-------CSENWKGESCDI-------PHCTD----NC---GFPH-RGICNASDT
-------RGCSCF-PHWQGPGCSIPVPANQSFWTR-----EEYSD--LKLPRASHKAV-V
NGNIMWVVGGYMFNHSDYSMVLAYDLTSREWLPL--N--HSVNSVVVRYGHSLALHKDK-
------------IYMYGGKID------STGNVTNELRVFHIHNESWVLLTPKAK------
-------DQYAVVGHSAHIVT------------LASG------RVVMLVIFGHCPLY-GY
ISVVQEYDLEKNTW-------------SILHTQGALVQGGYGHSSVYDDRTKALYVHG--
-GYKAFSANK--YRLADDLYR-YDVDTQMWTILKDS----RFFRYLHTAVIVS-G---TM
LVFGGNTHNDTSMSHG-------------------AKCFSSDFMAYDIACDRWSVLPRP-
---ELHHDVNRFGHSAV---------LYNSTMYVFGGFN---------------------
SLLLSDVLVFTS--------EQCDAHRSEAACVAAGPGIRCLWDTQSSRCTSWELATEEQ
A------EKLKSEC------------------FSKRT--------LDHDRCDQHTDCYSC
---------TANTNDCHWCN-----DHCVPVNHSC-------------------------
--TEGQISIAKYESCPKDNP----MYYCNKK----TSC--------RSCALDQN------
-------------CQWEPRNQECIALPENICGNGWHLVGNSCLKITTAKENYDNAKLSCR
NHNAFLASLTSQKKVEFVLKQLRLMQSSQSMSKLTLTPWVGLRKINVSYWCWEDMSPFTN
SLLQWMPSEPSDAGFCGILSEPSTRGLKAATCINPLNGSVCERPA---NHSAKQCRTPCA
LRTA-----CGECTSSSS------ECMWCSNMKQCVDSNAYVASFPFG-QCM--------
---EWYTMSS-C--------------------PPEN---C---SGYCTCSHCLEQPGC--
GW--------CTDP-----SNTG--KGKCIEGSYKGPVKMPSQASAGNVYPQPLLNSSMC
LE-DSRYNWSFI---HCP------------------------------------------
--------------------------------ACQCNGHSK----C-----INQSICEK-
CEDLTTGKHCETCISGF-YGDPTN-GGKCQPC--KCNG--HASLCNT-------------
------------------NTGKCF-------------CTTKGVKGDECQLC---------
--------------------------------------------------EVENRYQGNP
L-K--GTCYYTLLIDYQFTFSLSQEDDRYY----------TAINFVA-TPDEQNRDLDMF
INAS----------KNFNLNITWAT-----SFPAGTQTGEEV-------------PVVSK
TNIKE--YKDSFSNEKFDFRN----------HPNI---TFFV-----------YVSNFT-
-WPIKIQ-----------------------------------------IAFSQHSNFMDL
VQFFVTFFSCFLSLL-LVAAVVWKIKQ----------------------SCWASRRREQL
LREMQQMASRPFASVNVALETDE-------------EPPDLI-----------GGSIKTV
PK----------------------------------------------------------
----------------------------PIALE-PCFGNKAAVLS--------VFVRLP-
--R----GLGGIPPPGQSRSRCGQCPGGHFSADANSVQGEVRSCKKPEAAAACTAWNLHL
ILGQEFALTEGVWSTK---LSTGEAAGRKQAWGRRLGTLEASNSCA--------
>gi|47218515|emb|CAF98047.1|	Tetraodon nigroviridis
------------------------------------------------------------
--------------------------------------------------DGTQHCNQTC
YNECREGQ--------------------------------CSGSPRFE-----CECSLGW
TSDPPTLVLSGVECDVDCGCNFH----STCITAPGICDE---------------------
---------------------------------------CQDWTTGPHCEHCRPGSFGSA
L--AGGSGCVP---------------CECNGHGDPLQGYCHNQTGQCYCTHNTQGSHCES
CLPGYYGDPRNNGTCYRQCQGRSVLLSPAS--AAMPFSSSLGWLGGTEGKGGLSH-----
-CLWVLSVT---EKLAPCLPRQLCPPVALTLHPDSHTH--CKSSFVYVFDGLPRFLSNGV
VH----------SDHNLIGAFCGT-----------TRAQPITVEATSGVISVY--FEANV
SSNKPQGFNASFWVRKCHQGSDE-EEAG---------------------SPVCPSGSHCQ
GGI-CQ-------CPQGYGGPHCDR-------PVCPQ----DC---GITEGRGTCNT-SL
-------GVCVCS-DGWVGSDCSVPRDSNSLVWETLLDTQLTVNQAHRFLHRMGHSLVSE
PQGNLWMYGGLSLSEGMLGNVYRYSISERRWTQMLTSALEEGLTPRPRYHHASALLAHE-
SGSGNHGASHSFMLVVGGVTP--------HGVTADTWSLNLSSLIWREHPSSVL------
---------PPVAGHTLTVRR----------------------DSSVLLIGGYSPEN-GF
NHHLLEFNPQSGNW-------------TIAPHTGTPPTGLYGHSAVYHEQTDAVYVFG--
-GYRFHVETV--EPSG-ELYSLYYPNLT-WSLLVPS------------------------
--------------QG-------------------NK-----------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
---------------CKWCT------NC--PEGAC-------------------------
--ISSSVSCTSEHDCRINQREIFLSSNCTETSCEASDC--------PKCTASGK------
-------------CMWTRQ---------------FKRTGETRR-----------------
--------------------------------ILSVNPTYDWTCFSY-------------
-------------------------------------ALLNVSPMQVESSPPMPCPPPCH
TLQN-----CSLCLGSRGSDGGWQHCVWSMALQQCMSPSFVPLRCEAG-QCG--------
---RLLSGGDSC--------------------TPQ----C---SQLTQCSQCISRPQC--
GW--------CATR-----GGNG--AGRCLQGGLDG------------------VSEGVC
PL--RNSSWSFL---HCPEEDECANGHHHCNSTQDCHDLPQGFHCACKQGYILSSASGQC
EPVCAQGCVNGTCMSPGACQCHFGFVGDNCSSQCSCNKHSN----CA--GVNKPDVCLE-
CHNNTIGKHCEKCKPLF-VGSAKG-GGTCRPCREFCRG--NSDVCLSRNEYRKAREHSRL
FLLDPSSIPDWVSEGPTEENAVCV-------------NCQNNSLGDKCESCLGGYFLLQG
KCEKCQCNGHADTCNEHDGTGCPCQNNTETPSCLSSPQSDRKDCYRQQCAKCKDSFNGTP
VNG--RQCYRQFNVDTECCFDPTSQTNCFHDPTIRNLPKGRTVFFAA-QPKFTNVDIRVT
IDVTFGEVEVYVSNSHDTFIVELDR-----NTGIHTIKIEEESGSRGTTG-----PMLAH
NPLQ---LQAKPPGAEREIR-----------EERAEGLISYI-----------TVWKPQ-
-TVLIVRGVRDRVVITFPHEVHSLKSSRFYIALRGMGTEG-NEESQGLLFLRQDQAHIDL
FVFFSVFFSCFFLFL-SVCVLLWKVKQ----------------------FLDFRREQRRH
IQEMTKMASRPFAKITIYLEPEEPQLIYLPST-AGSTVTLGHTRATRIGGMVIAQRVRTG
PV-YKHDPGSGPTAHHHHLTMGGGGNNGQHLPLHYLNTHHYASSTAGTQASH--HHHPST
YSGYQHFCRSDPFLSQLMGFSYSTFKVGPITLE-PTDDGMAGVAT--------VLFQLP-
-------GGVLAPN-----RACLGSA----------------L----------------V
TLRQNL--QEYCGHGNGGGHP-GAGAGRKGLLGHQHLTTM----AM--------
>gi|115751480|ref|XP_785128.2|	Strongylocentrotus purpuratus
----------------------------------------------MIPLKRVILLMGFA
IVSLGGQVPSAMRPVHQEHMDQALNGSCICGTGWTGLRCDTPCPAGSYGPGCQHQCGCAS
GGSCDQFTGLCTCGVGLQGPHCNETCDPRFYGLNCINRCTCENDGICEPVNGTCKCATGW
QGESCDQPCPRGNYGINCQSSCLCRNGGSCHHITGLCTCSAGFTGTTCESRCTEGTYGVG
CSERCECQNGGNCSHVDEGYYGTNCS-------------SRCTCQHGDCNHVTGLCDVCR
PGWEGNLCDRRCTEGYYGNNCNQTCLCQNDGRCNHINGTCT-------CASGWRGEVCAE
SCPSGTYGRECLLECACSNGGSCRADNGGC--VC--------------TPGYHGTFC-DN
PCSENYYGQDCLEECLCQNDAACDHVTGNCTCLRGWDGPLCAVRCPSGYYGDGC-GQECR
CG----------NHSSVCDSETGA-----------CTCTS-GWLGEFCDVPCPNGYYGDN
CLLRC----ECQNDGRCDPATGDCSCADGFIGLSCDSDCHVFEVSMY--GPDCSLQCQCQ
NEAYCDHRDGSCTCTPGWIGQHCQD-------PCPDGFYGQGCNATCGCKNGGICDP-AM
-------GDCDCP-DGFMGDRCQDPCP--ENYYGR------RCSQ---------PCDC-R
NGGI----------------------------------------CNGVTGDCTCASGYT-
----------------GKSCS------QV--CPNGTYGPSCSENC----------LCADN
---------AICWHTDGTCICGAGFRGPLCEQPCHEGTFGANCSLSCRCVNGVCDGITGR
CSCLAGWKGDTCEWPCDFGYHGLGCSELCRCENGATCNNTNGNCTCADGWQGDVCDGPCD
LGFYGNECQE--TCSCEN-GA-NCDHVTGFCHCLPG------FIGVHCEVICPTGYFGSG
CSSPCTCQNEGVCEHT-------------------NGTCYCPAGFYGPTCELQCPQGLHG
AGCQVDCLCRNNATCDHVTGACQCQPGWIGALCETPCQD---------------------
GQYGDQCKEECP----CFHDSSCDHMTGACFCAKGYIGDMCQHLCPRPDLYFGLECEEPC
N------CPLGGLCHHVTGVCLCETLGDGSGAACSEPCDEGYYGNTCRMQCHCENGA-TC
---------DRVTGECS-CTPGWMGENC---TEPC-------------------------
--RPGYFGPDCSSLCRCKNGGT-----CDRS----GRCTCAPGWKGPSCAGECNPGTYGE
NCNSTCTCQHGGLCDHVTGGCRCQ----------PGYQGVNCE-----------------
--------------------------------RLCDEGFYGVL-----------------
------------------------------------------------------CQERCL
CVND------GICDPING------SCS-CQPGYQGRLCQYQCPVGTYGRDCSNICQCQNG
ATCDFRTGACTCGPGWQGEHCEYECSQGHYGYGCRERCAC---TNGASCHHVTGECSCTA
GWMGDYCNVQCREGLYGLGCNN---TCQCQNDGECNRF-------TGYCSCEDGWRETFC
ALPCHQG-WFGR---GCQQ-----------------------------------------
--------------------------------RCECLNGGE----C----DHVTGVCS--
CAPGWQGDNCASSCNKWQYGKDCN-----RTC--HCDG-ASASSCNP-------------
------------------VSGSCECMPGWSGRTCSEPCPPR-LFGTDCEMN---------
------CGCENGATCDHVDGSCTCKPGFRGVFCQDMCPNNIYGSGCINTCSCVNAYSCSP
S-T--GECLCLPGWTGERCDQPCPQGSYG-----------DSCNYTC-DCLVGDECDPVR
GRCN----------CSSDSEPLCQN-----GGTCNGRSCSCP-------------PGWMG
DHCETQCPTGRFGEDCTQMCTCWNNATCDRSNGECSCQPGWRGPICTSPCPDGFYGQWCR
LPCTCVNGGSCNHVTGECLCVPGYTGEHCEEAC---------------PAGTYGLQCQST
CSCLNGGICHGTTGD-CICQAGWEGAT---------------CSTPCSKGYYGNLCIEEC
QCQNGALCSPIEGSCTCEAGWL--------------GAYCHIPCDEGSYGQGCHKTCSHC
PQ-YRCANTDGRCLVLECDPGQWGEECEHICLCRNDGACDRLNGTCYCPLGFDGEFCEYE
FLPIDDDDNDSGKIITVNTGKRTGSAVPKVTVSVACTVIIIAIII--------AIVAVVM
WRKRRKRGAYKPHEEPQDPTYVMGTDINDSPGNEQVQMSRMSV----------------T
STGSFNMSDERELIGDTSPEQKEVFRRTKEDAGDVPNLSFKNPLYGDNMI----
>gi|157115796|ref|XP_001652701.	Aedes aegypti
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------MATTFILTDPSG--SV------------HDGLGNYSI---GV
KCSWLIDARDHNSIADKLSPAGSGKPSVIRLHLEEFATE-CGWDHLYVYDGDSV------
-------------ESPLLAVFSGLMYRK----NFSIRRIP-EVFAHSGSALLH--FFSDD
AYNMS-GFNISYEVNACPTVDTSLNCSG---------------------HGVCVYGE---
----CT-------CDIGWRGPACNV-------AICPN----NC---SAHLGRGACNV-IQ
-------RRCICA-KGFDGNDCSQVRA--HGVWTTIT---SEETAGFAPPGSASHGAA-V
FRDTFYIIAGETYGKAK-SLMYMYDFNGKVWETA--HT-DSKATPELRYGASTVMYGDK-
------------IFMYGGVVE------GK-GVCGELWAFDVSAKNWENITVKAE-QCNET
---YAMCGPLKSAGHTATLIS-------NFEGGKKGH------SQRMVVIFGHSPQF-GY
LNTVQEYNFGTREW-------------KIVRTRGYPVKGGYGHSAAYDPLKERIYVYG--
-GIISESDST--QLLSNKLYS-YEPHGRVWTLEAAA----PTARFLHTANFISPG---LM
MVFGGNTHNDTSHSFG-------------------AKCYSKDLMVYDVLCNSWHVQQMP-
--QDLRADLARFGHSAI---------SFEESLYIYGGFD---------------------
GQMINDMLKFTP--------GNCRALNRSDQCLNTRPGYKCIWDIQKSKCVPILDVDRGV
LFSRD--QINYDIC------------------PQESRLVMTRQAIQDYEHCSQLFSCQSC
---------VSTAYGCMFCGIGNGKGYC--AKEKC--------------------PDVSY
TYRADFYPTRELKDCPENDE----QI-CTQL----HGC--------HACTAYTF------
-------------CHWDYER-------------------SKCF-----------------
--------------------------------------YVGNKTSDI-------------
------------------------------------------------MNEALPCPPACS
VLTT-----CGNCTLE--------ECIWCQNEQRCVDKNAYTASFPYG-QCR--------
---EWTTGSNKCRAASS---------------GKSQ---C---GFYKTCAQCRDDPAC--
GW--------CDDG-----SMTG--LGKCLPGGDSGA-----------------HEEMEC
PA-AR---WHFT---HCP------------------------------------------
--------------------------------SCQCNGHST----C-----PDSKTCKQP
CKDPMMGSNCEKCKPGY-WGNPVN-GGTCQKC--ECNG--QAQYCHS-------------
------------------ETGKCF-------------CSTKGLAGDHCEKC---------
--------------------------------------------------DATNHYHGDP
S-R--GSCYYDLTIDYQFTFNLSKKEDRHF----------TQINFRN-SPIKSDIDADFS
ITCS----------MTARMNITIRT-----AGGPEK-------------------LLFAA
VNCST--FRYRFSKAEHHFGI----------EENVTLTTFYV-----------YVYDFQ-
-PPLWIQ-----------------------------------------IAFSQYPK-LNL
QQFFITFSTCFLLLL-LMAAILWKIKQ----------------------RYDMFRRRQRL
FVEMEQMASRPFSQVLVEIESK--------------EYNELSPAVENITSAP-RKRKKDS
PS----------------------------------------------------------
----------------------------PIALE-PCEGNRAAVLS--------LLVRLP-
--TGETSGGQQHSPPGQSAGLAVASA----------------L----------------V
TLGN----PRRPSIE----HPKEP-KTKRKQSQHPDS-------CI--------
>gi|109460304|ref|XP_217657.4|	Rattus norvegicus
MTWVHYSQNKLELNLNNNIMTVVTTKTFPLQPSEMSELFVAEVVPREQLRAPRSPSPHPA
LFLHPATWSVRGAFKTLLAAHAQLFVCSWEFLRKKKKKRAGDQGSAGAGASLSQPRPAEC
KAAFPPRS--------------------------------RDRSGFLLRGL--RSAGHTW
GRTPSGARRPGGRAGE-----------SRVPVRDRARPPLPDRGGASTNAWAREAAGTSV
RSLGCSRLYDDCVWQAEGSRLLRGLRLWRARPAGGGGASSWLLLDGNSWLLCYGFLYLAL
Y--AQVSQSKP---------------CERTGSCF--SGRCVNSTCL--CDPGWVGDQCQ-
-----------------HCQGRFKLTEPSG--YL------------TDGPINYKY---KT
KCTWLIEGY---------------PNAVLRLRFNHFATE-CSWDHMYVYDGDSI------
-------------YAPLVAVLSGLIVPE----VRGNETVP-EVVTTSGYALLH--FFSDA
AYNLT-GFNIFYSINSCPN-----NCSG---------------------HGKCTTSVSVA
SQVYCE-------CDKYWKGEACDI-------PYCKA----NC---GSPD-HGYCDLTGE
-------KLCVCN-DSWQGPDCSLNVPSTESYWIL-----PNVKPFSPSVGRASHKAV-L
HGKFMWVIGGYTFNYSSFQMVLNYNLESSIWNVG-----AVSRGPLQRYGHSLALYQEN-
------------IFMYGGRMET-----SDGNVTDELWVFNVRSQSWSTKTPTIL-GHGQQ
---------YAVEGHSAHIME------------LDSG------DVVMIVIFGYSAIY-GY
TSSIQEYHISSNTW-------------LVPETKGAIVQGGYGHTSVYDEMTKSVYVHG--
-GYKALPGNK--YGLVDDLYK-YEVNSRTWTILKES----GFARYLHSAVLIS-G---AV
LVFGGNTHNDTSLSNG-------------------AKCFSADFLAYDIACDEWKTLPKP-
---NLHRDVNRFGHSAV---------VINGSMYIFGGFS---------------------
SVLLNDILVYKP--------PSCKAFRDEELCRNAGPGIKCVWN--KNHCESWESGNA--
-------NLLRAKC------------------PPRTA--------ASDDRCYRYADCASC
---------TANTNGCQWCD----DKKCISASSNC-------------------------
--ST---SVRNYTKCHIRNE----QI-CNKL----TSC--------KSCSLNLN------
-------------CQWDQRQQECQALPAHLCGEGWNHVGDSCLRINSSRESYDSAKLYCY
NLSGNLASLTTSKEVGFVLDEI------QKNTQQRVSPWVGLRKINISYWGWEDMSPFTN
TSLQWLPGEPNDSGFCAYLERAAVAGLKANPCTSMADGLVCEKPVVSPNQNARPCKKPCS
LRTS-----CANCTSNGM------ECMWCSSTKRCVDSNAYIISFPYG-QCL--------
---EWQTAT--C--------------------SPQN---C---SGLRTCGQCLEQPGC--
GW--------CNDP-----SNTG--RGYCIEGSSRGPMKL-----AGVHNSEVALDTSLC
PK-EKNYEWSFI---QCP------------------------------------------
--------------------------------ACQCNGHST----C-----INNNVCEQ-
CKNLTTGRQCQDCMPGY-YGDPTN-GGQCTAC--TCGG--HANVCHL-------------
------------------HTGKCF-------------CTTKGIKGDQCQLC---------
--------------------------------------------------DSENRYVGNP
L-R--GTCYYSLLIDYQFTFSLLQEDDRHH----------TAINFIA-NPEQSNKNLDIS
INAS----------NNFNLNITWSV-----GSTGGTISGEET-------------PIVSK
MNIKE--YRDSFSYEKFNFRS----------NPNI---TFYV-----------YVSNFS-
-WPIKIQ-----------------------------------------IAFSQHNTIMDL
VQFFVTFFSCFLSLL-LVAAVVWKIKQ----------------------TCWASRRREQL
LRERQQMASRPFASVDVALEVGA-------------EQTDFL-----------RGPLEGA
PK----------------------------------------------------------
----------------------------PIAIE-PCAGNRAAVLT--------VFLCLP-
--R----GTSGAPPPGQS-GLAIASA---------------------------------L
IDIS----QQKPSDNK---DKTSGVRNRKHLSTRQGT-------CV--------
>gi|149738208|ref|XP_001499447.	Equus caballus
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-------------------MDI-----------------TLHLGKAYEITYVRLKFHTSR
P--ESFAIYKR---------------SRAGGPWEPYQYYSAS------CQKTYGRPEGQ-
------YLRPGEDERVAFCTSEFSDISPL-----------------SGGNVAFSTLE-GR
PSAYNFEESPVLQEWVTSTELLISLDRLNTFGDDIFKDP-RVLQSYYYAVSDFSVGGRCK
CH----------GHASAC----GPDAAG----RLVCLCQH-NTTGTDCERCRP--FFQDR
PWARG----TAEAANECLP----CNCSG--HSEECTFDRELFRSTGH--GGRCLRCRDHT
AGPHCER------CQENFYRWDRRT-------PCQPC----DCHPAGSLRLQ--CD--DA
-------GTCVCK-PTVTGWKCDRCLP---GFHSLSE---GGCRP----------CTC-N
PAGSL-------------------------------------GTCDPRSGRCPCKENVE-
----------------GNLCD------R---CRPGTFNLQPHNPA----------GCSSC
----------FCYGHSKVCAA--------------------------------AAGF-RE
HHILSDFRQGAEGW-----------------QVGSM--GGPEHPARWRPGGLPLNL-G--
-DEEELAAPE--KFLGDQRFS-YGQPLTLTFRGPPG-----GSPLPVQLRLEGAG---LA
LSLRHSSPSGPRDAGQ-------------------PGEVQLHFQLQETSEDVDPPLPPF-
---HFQRLLTNLTALRI---------QASSRGRSPPG-----------------------
QMFLMEVRLTSA----QRGLSPPASWVETCSCPKGYTGQFC------ESCAPGYKRETPL
-------GGPYANC----------------------------------VPCTCNQHG-TC
---------DPNTGICL-CGHHTEGPSC----ERC-------------------------
--LPGFYGNPFTGRADD----------C-------QPC---------PCPGQSA------
-------------CTTIPESREVVCTHCP-----PGQRGRRCE-----------------
---------------------------------TCDDGFFGDPLGL--------------
------------------------------------------------SGAPQPCQQ-CQ
CSGNIDPNTVGNCDPLSG------HCLRCLHNTTGAHCEHCQDGY-YG-SAL--------
---APRPADK-CMPCSCNPGG-----------SVSEQRPCDPVTGQCSCLPHVTGRDC--
GL--------CSPGFYDLQPGRGCQSCKCHPLGSQEDQCHPK---TGQCPCRPGVEGQAC
DR-CQLGFFGFSVK-GCR------------------------------------------
--------------------------------ACRCSPLGAASAQC-----HENSTCV--
CRPGFVGYKCDRCQDNF-FLTAS--GTHCQECP-SCYSLVKEEVAKLKARLTLMEGWLQG
S-----------------DCGITWGPLDILQGE----APRGDVYQGHHLVQGAREAFLEQ
VTGLEGAVKAAREQLRALSRKARCAQARAGKTCIQLADLEAALESSEEEILHAATVLA--
----------SLVIPQEGLGQPTNWSHLAA----------EARVLAR-SHRATATKIKAT
AQRA-------LLASNTSYVLLWSL-----LEGKVALEAQQELEDRYQ-------AVQEA
QKELGAAVAEALPEAERVLAA----------VQQVVTDTGLR-----------PASLPV-
-PVALPQAARAGDLDPRLQALEKTVASRERVVTEAARALQ-A------TARAALHKAEPL
TQLHQEARAALTRAS----SSVHAATV----------------------TVVGARTLLAD
LEGMKLRFPLPEDQAALMRKAGLVQDRILADARKKTKQAERMLGNAASVSSSARKKGREA
EL-------LAKDSAKLAKALLREGKQEYRRAGRLSSQTQAT-LRQASRQALALGAR---
GRELEEAEQVGAGLSKVERQIRES----RLSLE-KDIEALTELLD--------RLGSLD-
THQTPAQALNETQRALERLRLQLGPP--------GALQGKLRL----------------L
EQES----EQQELQIQSFESNLAEIRADKQNLEAILHSLPES--CANQQ-----
>gi|149634632|ref|XP_001513893.	Ornithorhynchus anatinus
------------------------------------------------------------
-----------------------------------------------------------M
GAGAPPGP--------------------------------GVGAGVRL---------LGY
R-----------------------------------------------------------
-----------------------------------------LLSLVLAAQLGRAQAGKAC
D--GTGSCF--------------------SGRCV--NSTCL-------CDQGWVGDRCQ-
-----------------HCQGRFKLTEPSG--YL------------TDGPINYKY---KT
KCTWLIEGY---------------PNAVLRLRFNHFATE-CSWDHMYVYDGDSI------
-------------YAPLIAVLSGLIVPE----VRGNETVP-EVVTTSGYALLH--FFSDA
AYNLT-GFNIFYSINSCPN-----NCSG---------------------HGKCTPSVSLP
SRVYCE-------CDKYWKGEACDI-------PYCKA----NC---GSPD-HGYCDLTGE
-------KLCVCN-DSWQGPDCSLNVPSTESYWIL-----PNVKPFSPSVGRASHKAV-L
HGKFMWVIGGYTFNYSSFQMVLNYNLESSIWNVG-----PISRGPLQRYGHSLALYKED-
------------IYMYGGKIET-----NIGNVTDELWVFNIQSQSWSTKIPTIL-GHGQQ
---------YAVEGHSAHIVD------------MDNK------DVIMIILFGYSSVY-GY
TSSIQEYSILHNTW-------------FVPETKGAIVQGGYGHTSVYEGMTKSIYVHG--
-GYKALPGNK--YGLVDDLYR-YEVNTKTWTILKES----GFARYLHSAVLIN-G---AM
LIFGGNTHNDTSLSNG-------------------AKCFSADFLAYDIACDEWKILRKP-
---NLHRDVNRFGHSAV---------VSNGSMYIFGGFS---------------------
SVLLNDILVYKP--------PNCEAFGNEELCKNAGPGIKCLWN--KNRCESWESGHTN-
-------NILRAKC------------------PPKPA--------AADDRCYRYADCASC
---------TANTNGCQWCD----DKKCISANSNC-------------------------
--SM---SVKNYTKCHVRNE----QI-CNKL----TSC--------KSCSLNLN------
-------------CQWDQRQQECQALPAHLCGEGWSHVGDACLRVNSSRENYDNAKLYCY
NLSGNLASLTASKEVEFVLDEI------QKYTLQKISPWVGLRKINISYWGWEDMSPFTN
TTLQWLPGEPNDSGFCAYLERAEVAGLKANPCTSMADGLVCEKPVVSPNQNARPCKKPCS
LRTT-----CSNCTSNGM------ECMWCSSTKRCVDSNAYIISFPYG-QCL--------
---EWQTAT--C--------------------SPQN---C---SGLRTCGQCLEQPGC--
GW--------CNDP-----TNTG--KGHCVEGSSRGPMRL-----SGIHTNEMVLDTSLC
PK-EKNYEWSFI---HCP------------------------------------------
--------------------------------ACQCNGHST----C-----INNNVCEQ-
CKNLTTGKQCQDCMPGY-YGDPTN-GGQCTAC--TCSG--HANICHM-------------
------------------HTGKCF-------------CTTKGIKGDQCQLC---------
--------------------------------------------------DSENRYLGNP
L-R--GTCYYSLLIDYQFTFSLLQEDDRHH----------TAINFIA-NPEQSNKNLDIS
INAS----------NNFNLNITWSI-----GSTAGTISGEEI-------------PVVSK
ANIKE--YRDSFSCEKFNFRS----------NPNI---TFYV-----------YVSNFS-
-WPIKIQ-----------------------------------------IAFSQHNTIMDL
VQFFVTFFSCFLSLL-LVAAVVWKIKQ----------------------TCWASRRREQL
LRERQQMASRPFASVDVALEVGA-------------EQTDFP-----------RGPLEGA
PK----------------------------------------------------------
----------------------------PIAIE-PCAGNKAAVLT--------VFLCLP-
--R----GSSGVPPPGQS-GLAIASA---------------------------------L
IDIS----QQKSADSK---EKSSGVRNRKHHLSTRQGT------CV--------
>gi|73991942|ref|XP_534360.2|	Canis familiaris
------------------------------------------------------------
--------------------------------------------MVAAAAATQARLRRRT
AATTAPAG--------------------------------RNGGQRRD-----WDAAGAE
RPGL-----------------------GAGLRL---------------------------
-----PRRRLLLLLLPP----L-----------------LLLPWAAEAAAAAAAVSGSAA
A--EAKECDRP---------------CVNGGRCNPGTGQCV-------CPAGWVGEQCQ-
-----------------HCGGRFRLTGSSG--FV------------TDGPGNYKY---KT
KCTWLIEGQ---------------PNRIMRLRFNHFATE-CSWDHLYVYDGDSI------
-------------YAPLIAAFSGLIVPE----RDGNETVP-EVVATSGYALLH--FFSDA
AYNLT-GFNITYNFDMCPN-----NCSG---------------------RGECKSSNS-S
NTVQCE-------CLENWKGEACDV-------PHCVH----DC---GFPD-RGVCNSSDD
-------RGCSCF-PEWQGPGCSIPVPANQSFWTR-----EEYSN--LKLPRASHKAV-V
NGNIMWVVGGYMFNHSDYNMVLAYDLASREWLAL--N--RSVNSVVVRYGHSLALYKDK-
------------IYMYGGKID------STGNVTNELRVFHIHNESWVLLTPKAK------
-------EQYAVVGHSAHIVT------------LKTG------RVVMLVIFGHCPLY-GY
ISNVQEYDLAKNTW-------------SILPTQGALVQGGYGHSSVYDRKTRALYVHG--
-GYKAFSANK--YRLADDLYR-YDVDTQMWTILKDS----RFFRYLHTAVIVS-G---TM
LVFGGNTHNDTSMSHG-------------------AKCFSSDFMAYDLACDRWSVLPRP-
---DLHHDVNRFGHSAV---------LHNSTMYVFGGFN---------------------
SLLLSDILVFTS--------EQCEAHRSEAACLAAGPGIRCVWDTVSSHCISWELATEAQ
E------EKLKSEC------------------FSKRT--------LDHDRCDQHTDCYSC
---------TANTNDCHWCS-----DHCVPVNHSC-------------------------
--TEGQISISRYENCPKDNP----MYYCNKK----TSC--------RSCALDQN------
-------------CQWEPRNQECIALPENICGIGWHLVGNSCLKITTAKENYDNAKLSCR
NHNAFLASLTTQKKVEFVLKQLRIMQSSQSMSKLTLTPWVGLRKINVSYWCWEDMSPFTN
SLLQWMPSEPSDAGFCGILSEPSTRGLKAATCINPLNGSVCERPA---NHSAKQCRTPCA
LRTA-----CGECTSGSS------ECMWCSNMKQCVDSNAYVASFPFG-QCM--------
---EWYTMSS-C--------------------PPEN---C---SGYCTCSHCLEQPGC--
GW--------CTDP-----SNTG--KGKCIEGSYKGPVKMPSQAPAGNSYPQPLLNSSMC
LE-DSRYNWSFI---HCP------------------------------------------
--------------------------------ACQCNGHSK----C-----INQSICEK-
CENLTTGKHCETCISGF-YGDPTN-GGRCQPC--KCNG--HASLCNT-------------
------------------NTGKCF-------------CTTKGVKGDECQLC---------
--------------------------------------------------EVENRYQGNP
L-K--GTCYYTLLIDYQFTFSLSQEDDRYY----------TAINFVA-TPDEQNRDLDMF
INAS----------KNFNLNITWAA-----SFSAGTQAGEEM-------------PVVSK
TNIKE--YKDSFSNEKFDFRN----------HPNI---TFFV-----------YVSNFT-
-WPIKIQ-----------------------------------------IAFSQHSNFMDL
VQFFVTFFSCFLSLL-LVAAVVWKIKQ----------------------SCWASRRREQL
LREMQQMASRPFASVNVALETDE-------------EPPDLI-----------GGSIKTV
PK----------------------------------------------------------
----------------------------PIALE-PCFGNKAAVLS--------VFVRLP-
--R----GLGGIPPPGQS-GLAVASA---------------------------------L
VDIS----QQMPIVYK---EKSGGVRNRKQQPPAQPGT------CI--------
>gi|126336016|ref|XP_001377786.	Monodelphis domestica
------------------------------------------------------------
-----------------MRLILGHQGWGLGGPELWLLLLLIVLAKAVVQNPDLPSAGCSR
GSCYPATG--------------------------------DLLVGRADRLTASSTCGLRG
PEPYCIVSHLQDE--------------KKCFLCDSRHPFSARYPQSHRIQNVVTSFAPQR
RSAWWQSENGVSSVTI-----------------------QLDLEAEFHFTHLIMTFKTFR
P--AAMLVERS---------------SDFGRTWRVYRYFSYD------CGSDFPGIPLA-
---------PPHRVDDVVCESRYSEIEPS-----------------TEGEVIYRVLDPAI
PITDPYSSR--IQDLLKITNLRVNLTRLHTLGDNLLDPRREIREKYYYALYELVVRGNCF
CY----------GHASQCARAPGAPSHAEGMVHGACVCKH-NTRGLNCESCQD--FYHDL
PWRPA----EDGHSHACKK----CECHQ--HSRSCHFDMAVFLASGNTSGGVCDDCQHHT
AGMHCEI------CRPFYYRDPTRDLRD--PAVCRPC----DCDPSGARD-GGLCDPHDD
PMLGLVSGQCRCK-EHVVGPRCQRCRD---GYFGLSTTNPQGCQR----------CQC-D
PRGTV----------------------------------PGGPPCDSNSGDCFCKRLVT-
----------------GKHCD------R---CLTDHWGLS-HDLL----------GCRPC
DCDVGGALEPRCAEDSGQCRC--------------------RRHMFGRRCDQVQPGY--F
LPFLDHLTLEAEKA-------------RGQALDVVERTARPGMTISWTGV----------
-GFVRLREGQILEFLVDS-VS-QAMDYELLLRYEPQ----VPEQWAEVTLTVQRPGPISH
SSPCGTTVAEDDHFRGMLQPGARYVVLPYPVCLEPGVSYTLLLELTRAGGDARPGAPTPT
LLLDSLVLLPRWSSLEMFSSGDAGALERRATFERYRCHEEGLMPAKSPPSEACAPLLRSL
AALLHNGALACQCDPQGSLSSECQPHGGQCPCKANVAGRRC------DHCAPGTFGFGPS
GCRACQCSPDGSFSSLCHEASGQCPCRPGAFGLRCDRCQPGQWGFPSCRPCHCNGHSDEC
---------DPRTGACQRCRDHTAGDNC----ERC-------------------------
--TAGFYGNPVLASGGH----------C-------RPC---------PCPEGPGGQRHFA
TS-----------CHQDRHSQQVVC-HCQ-----PGYTGPRCE-----------------
---------------------------------ECAPGHFGDP-----------------
------------------------------------------------QRPGGRCQP-CE
CSNNIDPMDPEACDRRSG------QCLRCLHHSEGPRCAHCRPGY-YG-QAA--------
--------HQSCRRCTCNFLGTERSQC-----PSQDKCRCDPGSGQCPCLPNIQGQSC--
DR--------CAPNFWNLASGRGCQPCSCHPSHATSPSCNEF---TGQCHCRAGFGGRTC
TE-CQENHWGDPGL-QCR------------------------------------------
--------------------------------ACDCDPRGIETPQC----HHATGHCV--
CRPGVAGVRCDQCARGF-SGVFPA----CQPCH-ACFGDWDRIVQGLASRTRALEQRSRE
LHQLGAL---GAFEKNFRLLGEKL-------------GTVQGIVNARNATAAATLQLMAT
TEDLRHDIEEATGQLTRLEGELTDAQDENFNANHALSGLERDGRALNLTLRQLGQHLDVL
KHSNFLGAYDSIRQSHAQSSEAEYHANRSA----------LAIPSPVSDSAATRRRAESL
MGSQ--------RDNFDRRNVANRRALGELAARANTLSLTGIN------------ELVCG
APGDA--PCATSPCGGAGCRD----------EDGQRRCGGLN----------------C-
-QGAAATADNA--LGRARHTQEELR----RTLGDADGLVG-KVAEARLQAGMARQRAQAA
LEKANETRGRVERANQELRELIQNVKDFLSQEGADPGSIEAVATHVLELSIPASPAQIHH
LAGEIAERVRSLGDVDTILQRTAGDV----------RQAEQLLQDAQRARTRAQGEKQKA
EM--------VQDALEEARRAQGAAKGAIRGAAADTEGTEQTLGRVREKTAGAEQDLTMA
AERTQRLDAQLDALKLKRAGNSLEATRAEETAN-SAQGRAQEAEKLLKGQLGDRYQTVRE
LADRKAQGVLQAKERAERLRDEARGL------LQDAQDKLRRM----------------Y
ELEGTYEVNERALEDKAAQLD-GLEAKMKGVLQSINQQIQIYNTCQ--------
>gi|91091298|ref|XP_970340.1|	Tribolium castaneum
------------------------------------------------------------
------------------------------------------------------------
---------------------------------------MLEIFQMFL-----FLFKSKY
R--------------------------RKCYVW---------------------------
---------------------------------------QALCCAVVVLNVCSLVKAKCA
D-------------------------CSGNGVCK--NETCV-------CYDGWQGPQCQ-
-----------------FCGGKVRLGTSTG--TI------------HDGLGNYSL---SV
KCSWLIDA----------------PNTSITLHLEEFATE-CGWDHLYIFDGDSV------
-------------DSPLLAVFSGLMYKG----DYNIRRIP-EIVAYSGSALVH--FFSDD
AFNMS-GFNMTYRLNACPSKISGVDCSG---------------------NGICIDQV---
----CT-------CNGGWTGVACHL-------QKCPD----NC---GQHDGRGRCE--PE
-------FGCRCE-SDYKGDDCSQYAP--SGYWET-----VNVES-FVPPGSASHGAA-V
WRDSMYVIAGESYSRR--FMLYVYDFNGNVWETP-----YISESPSQRYGHSTVIYGDK-
------------IFLYGGVM-------GNRGPTSEVWAFDINAKTWENITVKAV-ACNSS
---VLMCGPLKSAGHTATVIT---------------------------------------
---VQEYYFGTREW-------------HIVATKGYPVKGGYGHTATWDPLTGKIYVYG--
-GVVSENESA--QVLSKSLYS-YDPNTRVWVLLKDA----PSARFLHTSTFISGG---LM
LVFGGNTHNDTLHSFG-------------------AKCYSSEFLAYDVTCDTWQVLQVP-
--KDIHADLARFGHSAV---------TFEGSLYIYGGFD---------------------
GQMLSDMLKYTP--------GSCTNFITSNECLSKKPGVKCVWDMRNNFCTAIQNIPVKN
LTVQL--DGLIIRC------------------PELSRTMITQSLIQNENRCEKFEDCLSC
---------VQTTSECVWCG-----NSC-MHNKKCR------------------------
--NSSEANIAKLEQCPLDPSPI-----CKQL----HTC--------SACTSQPF------
-------------CRWR-----------------FEH--AKCV-----------------
--------------------------------T----HPLPSNVTAA-------------
------------------------------------------------AAEPIQCQKVCS
EYNS-----CLNCTQE--------ECIWCQNEGRCVDKNAYTASFPYG-QCR--------
---EWTTVGSKCRTRGAN--------------ENSQ---C---SFYSTCAKCRDDPAC--
GW--------CDDG-----SRTG--LGKCMPGGYAGP-----------TLHTHSLPSSTC
PP-DR---WHFT---TCP------------------------------------------
--------------------------------LCQCNGHAS----C----IANSSVCLP-
CQNLTMGTQCEHCVKGY-WGNPVN-GGKCQPC--ECNG--QATHCHP-------------
------------------ESGKCY-------------CTTKGLIGDHCEKC---------
--------------------------------------------------DATNHYNSDP
INK--DSCYYDLTIDYQFTFNLSKKEDRHF----------TQINFRN-SPIKADIDADFS
ITCS----------VLAKMNITIRR-----GGSKEEK------------------PIYED
FNCTT--FRTKFPKSDYNFGV----------EDNITLTTFYV-----------YVYDFQ-
-PPLWIQ-----------------------------------------ISFSQYPK-LNL
QQFFITFSSCFLLLL-LFAAILWKIKQ----------------------RYDMYRRRQRL
FVEMEQMASRPFSQVLVELEVK--------------EKLDFD----NISVIDLKRKKRDA
PS----------------------------------------------------------
----------------------------PIALE-PCYGNKAAVLS--------LLVRLP-
--T----GCEPYTVKGQSAGLAIASA----------------L----------------V
TLGN----PRKMSIDQVKTETKSG-KSRKSQSQHPDS-------CL--------
>gi|146741346|dbj|BAF62328.1|	Sus scrofa
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
----------------------------SG--FI------------TDGPGNYKY---KT
KCTWLIEGQ---------------PNRIMRLRFNHFATE-CSWDHLYVYDGDSI------
-------------YAPLVAAFSGLIVPE----RDSNETVP-EVVATSGYALLH--FFSDA
AYNLT-GFNITYNFDMCPN-----NCSG---------------------RGECKISNS-S
NTVQCE-------CSENWKGEACDI-------PHCVN----NC---GFPH-RGICNSSDV
-------RGCSCF-SEWQGPGCSVPVPANQSFWTR-----EEYTN--LKLPRASHKAV-V
NGNIMWIVGGYMFNHSDYNMVLAYDLASREWLAL--N--SSVNSVVVRYGHSLALYKDK-
------------IYMYGGKID------STGNVTNELRVFHIHNESWVLLTPKAK------
-------EQYAVVGHSAHIVT------------LTSG------RVVMLVIFGHCPLY-GY
ISNVQEYDLDKNTW-------------SILHTQGALVQGGYGHSSVFDHITRALYVHG--
-GYKAFSANK--YRLADDLYR-YNVDTQMWTILKDS----RFFRYLHTAVIVS-G---TM
LVFGGNTHNDTSMSHG-------------------AKCFSSDFMAYDIACDRWSVLPRP-
---DLHHDVNRFGHSAV---------LHNSTMYVFGGFN---------------------
SLLLSDILVFTS--------EECEAHQSEAACLAAGPGIRCVWDTGSSQCVSWELATEAQ
R------AKLNSEC------------------FFKRT--------LDHDRCDQHTDCYSC
---------TANTNDCHWCN-----DHCVPMNHSC-------------------------
--TEGQISIAKYENCPKDNP----MYYCNKK----TSC--------RSCALDQN------
-------------CQWEPRNQECIALPENICGIGWHLVGNSCLKITTAKENYDNAKLSCR
NHNAFLASLTTQKKVEFVLKQLRTMQSSQSMSKLTLTPWVGLRKINVSYWCWEDMSPFTN
SLLQWMPSEPSDAGFCGILSEPSSRGLKAATCINPLNGSVCERPA---NHSAKQCRTPCA
LRTA-----CGECTSGSS------ECMWCSNMKQCVDSNAYVASFPFG-QCM--------
---EWYTMSS-C--------------------PPEN---C---SGYCTCSHCLEQPGC--
GW--------CTDP-----SNTG--KGKCIEGSYKGPVKMPSQAPSGSSYPQPLLNSSMC
LE-DSRYNWSFI---HCP------------------------------------------
--------------------------------ACQCNGHSK----C-----VNQSVCEK-
CENLTTGRHCETCISGF-YGDPTN-GGKCQPC--KCNG--HASLCNT-------------
------------------NTGKCF-------------CTTKGVKGDECQLC---------
--------------------------------------------------EVENRYQGNP
L-K--GTCYYTLLIDYQFTFSLSQEDDRYY----------TAINFVA-TPDEQNRDLDMF
INAS----------KNFNLNITWAA-----SFSAGTQAGEEM-------------PVVSK
TNIKE--YKDSFSNEKFDFRN----------HPNI---TFFV-----------YVSNFT-
-WPIKIQ-----------------------------------------IAFSQHSNFMDL
VQFFVTFFSCFLSLL-LVAAVVWKIKQ----------------------SCWASRRREQL
LREMQQMASRPFASVNVALETDE-------------EPPDLI-----------GGSIKTV
PK----------------------------------------------------------
----------------------------PIALE-PCFGNKAAVLS--------VFVRLP-
--R----GLGGIPPPGQS-GLAVASA---------------------------------L
VDIS----QQMPIVYK---EKSGAVRNRKQQPPAQPGT------CI--------
>gi|119904223|ref|XP_597117.3|	Bos taurus
MSLYHHPSHFTDEDTEAQRAKVLPAEPGQGSRGAESPAGHSRARPPVGPARRGEARSAPT
GGAGPEAGAQSRARTAERRVVGGPPTMGTAAALLLSLALLAPRAAGARMGACYDGAGR-P
QRCLPVFE--------------------------------NAAFGRLA-----EASHTCG
RPPEDFCPHVGAQGAG-----------APCQRCDAADPARH------HNASYLTDFHSQD
DSTWWQSPSMAFGVQYPTSVNI-----------------TLNLGKAYEITYVRLKFHTSR
P--ESFAIYKR---------------SRAGGPWEPYQYYSAS------CQKTYGRPEGL-
------FLRPGEDERVAFCTSEFSDISPL-----------------SGGNVAFSTLE-GR
PSAYNFEESPVLQEWVTSTELLVSLDRLNTFGDDIFKDP-KVLQSYYYAVSDFSVGGRCK
CN----------GHASEC----GPDEEG----RLACRCQH-NTTGTDCERCLP--FFQDR
PWARG----TAEAANECLP----CNCSG--HSEECTFDRELFRSSGH--GGRCLHCRAHT
AGPHCER------CQENFYRWSPQT-------PCQPC----DCHPAGSLRLQ--CD--DL
-------GTCVCK-PTVMGWKCDRCLS---GFHSLSE---GGCRP----------CTC-N
PVGSL-------------------------------------GTCDPRSGRCHCKENVE-
----------------GSLCD------R---CRPGAFNLQPHNPA----------GCSSC
----------FCYGHSKVCVA--------------------------------AAQF-QE
HHILSDFRQGAEGW-----------------RAGSV--GDPGHPARWSPGGLLLDPED--
-EEAELTAPE--KFLGDQRFS-YGQPLTLTFQVPRG------SSLSTQLRLEGAG---LA
LTLRHSGSPRTPVSGQ-------------------AGEVRLKFLLQETSEDVDPPLSAF-
---HFQRVLANLTALRI---------RTSGHSTSSSG-----------------------
PVLLTEVRLTSA----RRGLSPPASWVETCSCPQGYTGQFC------ESCAPGYKRNTPL
-------GGPYASC----------------------------------VPCTCNQHG-TC
---------DPNTGVCL-CGHHTEGPSC----ERC-------------------------
--LPGFYGNPFTGQADD----------C-------QPC---------PCPGQSA------
-------------CTTIPESGEVVCTHCP-----RSQRGRRCE-----------------
---------------------------------ICDDGFFGDPLGL--------------
------------------------------------------------SGRPQPCQP-CQ
CSGNVDPNAVGNCDPLSG------RCLRCLHNTTGAHCGHCREGF-YG-SAL--------
---APRPADK-CAPCSCNPEG-----------SVSEQRPCDPVTGQCSCLPHVTGRDC--
GH--------CSPGFYDLQPGRGCRRCKCHPWGSQEDQCHPK---TGQCPCRPGVEGQTC
DR-CQLGFFGFSVK-GCR------------------------------------------
--------------------------------DCRCSPLGATSPQC-----HENSTCV--
CRPGFVGYKCDRCQDNF-FLTAS--GRQCQECP-SCYALVKEEAAKLKARLTLMEGWLQG
S-----------------DCGRPWGPLDILQGE----APRGDIYQGPHLLQGAQEAFLEQ
VTGLEGAVKAAREQLQALGRSARCAQAGVEKTCIQLADLEAALESSEEEILHAATILA--
----------SLVIPQEGLGQPTNWSKLAT----------EAHALAR-SHRDTAAKIEAT
ARRA-------LLASNTSYALLWSL-----VEGRAALEAQQELEDRYQ-------EVQAA
QKALGTAVAEALPEAERVLAA----------VQQAGVAAALH-----------LASPSA-
-PASPPQKSQAEAVSLKVQTLEKTVTSREHMVTEAAGSLQ-A------TAQAVLQEMEPL
TQLHQEARAALTRASSSVQAA----TV----------------------TVMGARTLLAD
VEGMKPRFPRPKDQAALRRKAAIVQDRILADSRKKTKQAERMLGDAASVSSRAKKKGREA
EL-------LAQDSAKLAKALLRAGKQEHRRASGLSSQTRATLG----LASRQLLASEAH
RQELEAAEWDGAGLSQMERQIRES----RTSLE-KDIKALLDLLA--------RLGSLD-
THRAPARALNETQWALERLRLRLSPP--------GALQGKLSL----------------L
EQES----KLQELQIQSFENDLSELRADKQNLEAILHSLPES--CASWQ-----
>gi|109092720|ref|XP_001115192.	Macaca mulatta
------------------------------------------------------------
--------------------------------------------MVAAAAATEARLRRRT
AATAALAG--------------------------------RSGWPHRD-----WDVTRAG
RPGL-----------------------GAGLRLPRLLSPPL-------------------
----RPRLLLLLLLLSPPLLLL-----------------LLLPCEAEAAAAAAAVSGSAA
A--EAKECDRP---------------CVNGGRCNPGTGQCV-------CLAGWVGEQCQ-
-----------------HCGGRFRLTGSSG--FV------------TDGPGNYKY---KT
KCTWLIEGQ---------------PNRIMRLRFNHFATE-CSWDHLYVYDGDSI------
-------------YAPLVAAFSGLIVPE----RDGNETVP-EVVATSGYALLH--FFSDA
AYNLT-GFNITYSFDMCPN-----NCSG---------------------RGECKISNN-S
NTVECE-------CSENWKGEACDI-------PYCTD----NC---GSPR-RGICNSSDV
-------RGCSCF-SGWQGPGCSVPVPANQSFWTR-----EEYSN--LKLPRASHKAV-V
NGNIMWVVGGYMFNHSDYNMVLAYDLASREWLPL--N--RSVNNVVVRYGHSLALYKDK-
------------IYMYGGKID------STGNVTNELRVFHIHNESWVLLTPKAK------
-------EQYAVVGHSSHIVT------------LKNG------RVVMLVIFGHCPLY-GY
ISNVQEYDLDKNTW-------------SILHTQGALVQGGYGHSSVYDHRTRALYVHG--
-GYKAFSANK--YRLADDLYR-YHVDTQMWTILKDS----RFFRYLHTAVIVS-G---TM
LVFGGNTHNDTSMSHG-------------------AKCFSSDFMAYDIACDRWSVLPRP-
---DLHHDVNRFGHSAV---------LHNSTMYVFGGFN---------------------
SLLLSDILVFTS--------EQCDGHRSEAACLAAGPGIRCVWDTGSSQCISWALATDEQ
E------EKLKSEC------------------FSKRT--------FDHDRCDQHTDCYSC
---------TANTNDCHWCN-----DHCVPRNHSC-------------------------
--TEGQISIFRYENCPKDNP----MYYCNKK----TSC--------RSCALDQN------
-------------CQWEPRNQECIALPENICGIGWHLVGNSCLKITTAKENYDNAKLFCR
NHNAVLASLTTQKKVEFVLKQLRIMQSSQSMSKLTLTPWVGLRKINVSYWCWEDMSPFTN
SLLQWMPSEPSDAGFCGILSEPSTRGLKAATCINPLNGSVCERPA---NHSAKQCRTPCA
LRTA-----CGECTSGSS------ECMWCSNMKQCVDSNAYVASFPFG-QCM--------
---EWYTMST-C--------------------PPEN---C---SGYCTCSHCLEQPGC--
GW--------CTDP-----SNTG--KGKCIEGSYKGPVKMPSQAPTGNFYPQPLLNSSMC
LE-DSRYNWSFI---HCP------------------------------------------
--------------------------------ACQCNGHSK----C-----INQSICEK-
CENLTTGKHCETCISGF-YGDPTN-GGKCQPC--KCNG--HASLCNT-------------
------------------NTGKCF-------------CTTKGVKGDECQLC---------
--------------------------------------------------EVENRYQGNP
L-K--GTCYYTLLIDYQFTFSLSQEDDRYY----------TAINFVA-TPDEQNRDLDMF
INAS----------KNFNLNITWAA-----SFSAGTQAGEEM-------------PVVSK
TNIKE--YKDSFSNEKFDFRN----------HPNI---TFFV-----------YVSNFT-
-WPIKIQ-----------------------------------------IAFSQHSNFMDL
VQFFVTFFSCFLSLL-LVAAVVWKIKQ----------------------SCWASRRREQL
LREMQQMASRPFASVNVALETDE-------------EPPDLI-----------GGSIKTV
PK----------------------------------------------------------
----------------------------PIALE-PCFGNKAAVLS--------VFVRLP-
--R----GLGGIPPPGQS-GLAVASA---------------------------------L
VDIS----QQMPIVYK---EKSGAVRNRKQQPPAQPGT------CI--------
>gi|125773259|ref|XP_001357888.	Drosophila pseudoobscura
------------------------------------------------------------
------------------------------------------------------------
-----------------------------------------PTTTTTS-----PTFNAKY
R--------------------------RKCLLLL--------------------------
---------------------------------------TLLLFHGCFSGLHRASAYNCT
A--HGSR-------------------CQNDGQCQE-DGQCL-------CADGWQGPECQ-
-----------------FCGGKVRMYHPMG--TI------------HDGWGNYSV---SV
KCSWLIDAR--HPHWGRRHNANSPRTSNIRIHLREFATE-CGWDHLYIYDGDSV------
-------------DSPLLAVFSGLMYRG----NFSIRHVP-QVIARSGTALVH--FFSDD
AYNMS-GFNLTYKMNGCPTDSDEVECSG---------------------HGKCRDGD---
----CI-------CDPMYRGEACNM-------AACPG----NC---MEEKNQGHCRL-DQ
-------ERQVSA-HGA---------------WTTVH---PKHSP--APAGSASHGAT-V
WRDTLHIVGGESYGRG--ELMSTYDFNGNVWETV--HPEDGGEVPDKRYGSSTVMYGDK-
------------IFMYGGVIK------GQ-GISNELWAFDVSAKTWENITVRTD-ACNVT
TGPSGMCGPLHVVGHTATLVP---------GFGDKNN------YQYMVVIFGHSPHY-GY
LNTVQEFNFGSREW-------------RIVQTSGFVVKGGYGHSAAYDFLTEKVYVYG--
-GIVSESESS--QVLSSRLYA-YEPSTRIWSLLSSA----PSARLLHTANFVNQG---LM
MVFGGNTHNDTSTSYG-------------------AKCYSKDLLVYDVYCDSWHFHQMP-
--SYLQADLARFGHSSV---------VFEDALYIYGGFN---------------------
GQLLNDILRYQP--------GYCSYYTKQEKCTSARPGIKCIWDVQKMRCISITQVQRSA
IYGRE--QYDYVAC------------------PSKSRLTMTSELLHDVLRCQELGNCQSC
---------VSTAFDCTYCG----NGVC--SKERCRETTSVASVFLELSTTHQSVPQVPA
STVGPPLNAKQLVACPVSEDFLMQSV-CEQL----HNC--------RACSSNAA------
-------------CKWDTEQ-------------------NRCR-----------------
--------------------------------SHGSSSTAGGPVSNR-------------
------------------------------------------------TQDDVVCPPACA
TLTN-----CQNCTED--------ECIWCQNEQRCVDRNAYTASFPYG-QCR--------
---EWTTFTAKCRSSPV--TALSIGTT--TALSSAQ---C---GYYNSCQQCLDDPAC--
GW--------CDNG-----SNTG--LGRCVVGGALAP-----------------YDETEC
AL-KH---WFFT---SCP------------------------------------------
--------------------------------RCNCNGHSV----C-----NDQQHCEQP
CNNLTTGVHCEKCRTGY-WGSPIN-GGKCQRC--ECND--QGVYCHP-------------
------------------DTGKCY-------------CTTKGIVGDHCEKC---------
--------------------------------------------------DSQNHYHGDP
L-K--GSCYYELTIDYQFTFNLSKKEDRHF----------TQINFRN-SPGKPEIDADFT
ITCS----------VPAKMDISVKR-----AGSPDM-------------------LILVG
VNCST--FRHRFPKTEYQFGHSP--------DDNSSLTTFYV-----------FVHDFQ-
-PPIWIQ-----------------------------------------IAFSQYPK-LNL
QQFFITFSSCFLLLL-LMAAVLWKIKQ----------------------KYDMFRRRQRL
FVEMEQMASRPFSQVLVDIENR--------------ESIDLSLTLEGIGHMS-KKRKKEC
PS----------------------------------------------------------
----------------------------PIALE-PCCGNRAAVLS--------LLVRLP-
--T----GGQSQAPTGQSNGLAVASA----------------L----------------V
TLG-----PRRPSMEQ---HPKEP-KSKRKQSQHPES-------CT--------
>gi|125839764|ref|XP_687623.2|	Danio rerio
------------------------------------------------------------
----------------------------------------MLLHLFSDANYNLLGFNATY
TFSVCPGD--------------------------------CSGHGRCDVATARCQCQQGW
GGLDCNTPLCSQACTQRGHGICDKRGLKCICSSGFVGQDCQLGLRDNSGAGQWWEVSSGD
VKAAPRTSSAGVYLASTGAMYM-----------------FGDWTTGPHCEHCKPGSFGSA
L--ARGDGCVP---------------CQCNGHGDPLQGFCHNQTGQCYCTHHTQGPHCES
CLPGYYGDPRDNGTCFSQCQGRSVLLSSSVPLSLSSSLGWHGAVGGHGGVGGHGG---LS
HCLWVLSVS---QDLAPCMPGQSCPPVALTWHPDSHTH--CTNSYVYVFDGLPRFLSNGV
VH----------SHHNLIGAFCGT-----------TRMEPITVEATSGVVSVY--FEANV
TSGRAQGFNASFWVKRCGNGSTDEGTVI---------------------SAECQAGAQCI
NGL-CE-------CPHGLGGPQCDR-------PVCPG----SC---GAEEGRGTCNM-NL
-------GLCVCT-EGWAGSDCSSISDTDSLVWETLLDTQLSVNKAHRFLRRMGHSLMSS
PQGTLWMYGGLSLSEGILGNVYRYSVADRRWTEVLTSSVEESSMPLPRYHHASALVYYQF
PISGSHSATRNLMFVVGGVTK--------EGVANDTWCLNLDSQEWKQYKSSVL------
---------PPVAGHTLTVRK----------------------GSSVLLIGGYSPEN-GF
NHHLLEFSPQSGNW-------------TIALHTGTPPTGLYGHSAVYHEQTDAVYVFG--
-GYRFHVEAV--EPSG-ELYSLYYPNLT-WSLLVPSQGNKPLSRFFHAAALVKD----TM
VIVGGRT--------G-------------------EEDYSNTVSLYQINCNTW-IQPVS-
---SVGEPVNSSVSLAM--------TVWGDRLFLSGGFN---------------------
GVTLGRFLTLSL------PSDPCILLPTPEACNSSTGS--CVWC--RGTCASSDAAERLG
C------TLGLSTC------------------SPTPR---------SPDQCRRLKTCSEC
LARHPKTFSSPSALQCKWCT------NC--PEGAC-------------------------
--ISSSVSCTSEHDCRINQREIFLSSNCTETSCEASDC--------PKCTASGK------
-------------CMWTRQ---------------FKRTGETRR-----------------
--------------------------------ILSVNPTYDWTCFSY-------------
-------------------------------------ALLNVSPMQVESSPPMPCPEPCH
EIKT-----CSQCLSSRGSDGGWQRCVWSMALQQCMSPSFVPLRCEAG-QCG--------
---RLLSDEDSC---------------------SPQ---C---FQLTQCSQCISRPQC--
GW--------CAGR-----GGNG--SGRCLQGGLNG------------------VSEALC
PQ-WNSS-WSFL---HCPEEDECSNGHHHCNVTQDCHDLPEGYHCTCRQGYVLSSVSGQC
EPVCAQGCVNGTCISPGICQCHFGFVGENCSSQCRCNKHSN----CK--SISQLDTCLE-
CKNNTKGQHCDKCKPLF-VGSAMG-GGMCRPCREFCRG--NSDICLSKDEHNKAMENPKD
YPLDRESIEQWATEGPTEDHAVCV-------------SCQNNSVGDKCESCLSGYFLLQG
KCEKCQCNGHADTCNEHDGTGCPCQNNTETSSCLSSPQNDRKECYRQQCAKCKESFNGNP
VNG--RQCYRQFNVDSECCFDPTSQVNCFHEPNIRNLLRGRTVFFSA-QPKFTNVDIRVT
IDVTFGEVEVYVSNSHDTFIVQVDR-----QSGVHTIKIEDEATSATASRGEKEVPLAPP
SPMKV--FANSSSALLGTLSAKLQGSEREVREERAEGLITYI-----------TVWKPQ-
-TVLIVRGVRDRVVITFPHEVHSLKSSRFFIALRGVGTETHNGESQGLLFLRQDQAHIDL
FVFFSVFFSCFFLFL-SVCVLLWKVKQ----------------------FLDFRREQRRH
IQEMTKMASRPFAKLTVYLEPEEPQLVYLPSAGGGSAVSLAHVRTGKLGGMVMGQRGRPG
ALSYKHDPGTGTATHHHHHLALSGGNNGQHLPLHYLNAHHYAPSSTANPTSHHQHHYPSS
HGSYQHFCRSDPFLSQLMGFSYSSFKVGPITLE-PTDDGMAGVAT--------VLIQLP-
-------GGILAPN-----RACLGSA----------------L----------------V
TLRQNL--QEYCGHGGAGTHP-GAGGGRKGLLGHQHLTTM----AM--------
>gi|122889249|emb|CAI39530.2|	Homo sapiens
-------------------------------------------PPPPAPPSSLPAPQGKA
GPGGQRAVRAHPSRAGPAERAASVPLTMAAAALLLGLALLAPRAAGAGMGACYDGAGR-P
QRCLPVFE--------------------------------NAAFGRLA-----QASHTCG
SPPEDFCPHVGAAGAG-----------AHCQRCDAADPQRH------HNASYLTDFHSQD
ESTWWQSPSMAFGVQYPTSVNI-----------------TLRLGKAYEITYVRLKFHTSR
P--ESFAIYKR---------------SRADGPWEPYQFYSAS------CQKTYGRPEGQ-
------YLRPGEDERVAFCTSEFSDISPL-----------------SGGNVAFSTLE-GR
PSAYNFEESPGLQEWVTSTELLISLDRLNTFGDDIFKDP-KVLQSYYYAVSDFSVGGRCK
CN----------GHASEC----GPDVAG----QLACRCQH-NTTGTDCERCLP--FFQDR
PWARG----TAEAAHECLP----CNCSG--RSEECTFDRELFRSTGH--GGRCHHCRDHT
AGPHCER------CQENFYHWDPRM-------PCQPC----DCQSAGSLHLQ--CD--DT
-------GTCACK-PTVTGWKCDRCLP---GFHSLSE---GGCRP----------CTC-N
PAGSL-------------------------------------DTCDPRSGRCPCKENVE-
----------------GNLCD------R---CRPGTFNLQPHNPA----------GCSSC
----------FCYGHSKVCAS--------------------------------TAQF-QV
HHILSDFHQGAEGW-------------WARSV------GGSEHPPQWSPNGVLLSPE---
-DEEELTAPE--KFLGDQRFS-YGQPLILTFRVPPG-----DSPLPVQLRLEGTG---LA
LSLRHSSLSGPQDAGH-------------------PREVELRFHLQETSEDVAPPLPPF-
---HFQRLLANLTSLRL---------RVSPGPSPAG------------------------
PVFLTEVRLTSA----RPGLSPPASWVEICSCPTGYTGQFC------ESCAPGYKREMPQ
-------GGPYASC----------------------------------VPCTCNQHG-TC
---------DPNTGICV-CSHHTEGPSC----ERC-------------------------
--LPGFYGNPFAGQADD----------C-------QPC---------PCPGQSA------
-------------CTTIPESREVVCTHCP-----PGQRGRRCE-----------------
---------------------------------VCDDGFFGDPLGL--------------
------------------------------------------------FGHPQPCHQ-CQ
CSGNVDPNAVGNCDPLSG------HCLRCLHNTTGDHCEHCQEGF-YG-SAL--------
---APRPADK-CMPCSCHPQG-----------SVSEQMPCDPVTGQCSCLPHVTARDC--
SR--------CYPGFFDLQPGRGCRSCKCHPLGSQEDQCHPK---TGQCTCRPGVTGQAC
DR-CQLGFFGFSIK-GCR------------------------------------------
--------------------------------ACRCSPLGAASAQC-----HENGTCV--
CRPGFEGYKCDRCHDNF-FLTAD--GTHCQQCP-SCYALVKEEAAKLKARLTLTEGWLQG
S-----------------DCGSPWGPLDILLGE----APRGDVYQGHHLLPGAREAFLEQ
MMSLEGAVKAAREQLQRLNKGARCAQAGSQKTCTQLADLEAVLESSEEEILHAAAILA--
----------SLEIPQEGPSQPTKWSHLAT----------EARALAR-SHRDTATKIAAT
AWRA-------LLASNTSYALLWNL-----LEGRVALETQRDLEDRYQ-------EVQAA
QKALRTAVAEVLPEAESVLATVQ--------QVGADTAPYLA-----------LLAS---
-PGALPQKSRAEDLGLKAKALEKTVASWQHMATEAARTLQ-T------AAQATLRQTEPL
TKLHQEARAALTQASSSVQAA----TV----------------------TVMGARTLLAD
LEGMKLQFPRPKDQAALQRKADSVSDRLLADTRKKTKQAERMLGNAAPLSSSAKKKGREA
EV-------LAKDSAKLAKALLRERKQAHRRASRLTSQTQAT----LQQASQQVLASEAR
RQELEEAERVGAGLSEMEQQIRES----RISLE-KDIETLSELLA--------RLGSLDT
-HQAPAQALNETQWALERLRLQLGSP--------GSLQRKLSL----------------L
EQES----QQQELQIQGFESDLAEIRADKQNLEAILHSLPEN--CASWQ-----
>gi|156547421|ref|XP_001604560.	Nasonia vitripennis
------------------------------------------------------------
------------MLLRLLLLAAAWCVASAEPDPAIEFNRI-PNL--RDEDKCYDSNGR-P
QRCKPPFE--------------------------------NAAFNVLIEAT--NTCGQDG
RGTP-FCKQTAI--DK-----------KSCDVC---YEG-D------HPAAYLTDQNTNE
KPTWWQSQTMFEGIQYPNQVNL-----------------TLNLGKTFDITYVRVLFESPR
P--ESWGIYRR---------------KNEKSPWEPYQFYSAT------CRDTYGLPESK-
------ETIRGE-DTRVLCNSVYSDIVPL-----------------SKGVVAFSTLE-GR
PSAYKFETNEELQDWVQATDLRITLDRLNTFGDEVFGDD-QVLQSYYYAIADVAVGARCA
CN----------GHAGECVNSTSVDGRT----RRVCRCEH-FTTGPDCNECLP--FYNDA
PWGRA----TIYDAHECKP----CNCNG--YSDTCYFDKELYRLTGH--GGHCTDCRDNR
DGANCEH------CRENYYARPEDG-------YCIAC----NCNEIGSRSLQ--CN--AE
-------GKCQCK-PGVTGDKCDRCAA---NFFDFSN---YGCTS----------CEC-N
EAGSL----------------------------------YNTPSCDPVTGICTCKDNVE-
----------------GKRCR------E---CRPGFFNLDEDNEF----------GCTPC
----------FCYGHSSLCST--------------------------------ASGY-SR
VNIESSFVRGNERW--------------------SANVAGKAMPVTYDSISQSISATAAD
RDNVYFVAPD--RFLGDQRTS-YNQDLSFTLKISDN----GPAPTARDIILEGGNG--QQ
ITQPIFGQNNSLPSTN-------------------ATEFI--FRLHEHPDYGWLPRLNS-
--RAFISILANLTSIKV------------RGTYTHQGKG---------------------
--ELYDVKLETA---HRGAAGEPADWVEHCNCPTGYVGQFC------ESCAPGYHHDPPN
-------GGPFALC----------------------------------VLCNCNGHADIC
---------EAETGQCI-CQHNTAGSNC----EHC-------------------------
--ARGFYGHS-LKGTPDD---------C-------QPC---------PCPDNGP------
-------------CILLGNNPDPICSECP-----VGRTGPRCE-----------------
---------------------------------ICSDGYFGNP-----------------
-------------------------------------------------ERGIPCRP-CE
CNNNIDLNAVRNCNQETG------ECLKCVNNTAGAHCEECLPGY-YG-DAL--------
----SDQKDDGCKLCQCYPPGTQERADG----GVAP---CDQLTGHCFCKSHVIGRNC--
DQ--------CEDGYYHIRGGEGCIACNCDLEGSYNRTCDAI---TGQCSCRPGVTGQRC
DA-CLPYQYGFSRD-GCR------------------------------------------
--------------------------------ACECDKIGSHDMQC----DAN-GQCP--
CLPNVEGRTCNRCKENK-YNRQY--G--CIDCP-PCYNLVQDAVNEHRGRLAELEDNLRK
IKSNPTVINEEGFKQKLSDVQNRV-------------RDLLELAKSGSGSGSDKKSLVEQ
LDELRDQLTEISNTLQNVDQTASDTNRTTSQGRMSIDEAEKVLDKIHEQLTEAEDYLATD
-----GQS--ALAEAKKRAEHVGQQNEQMTAIAQ------EARSIAD-SNIKEAKRLQEV
AEQA-------KNTSLEAYNLAKKA-----IAKYTNISDEIR-------------LLENK
LIALEERYGDVKKLTATAVAK----------SDTVSKEAVSL-----------LLLGISL
-PEVNLTDLQNR-VEEVNKEAAKIKDQAKILLDENIDLIH-DIEDKVRKSEDLLYKAEDQ
QTITAELLAEVDDANNVAKNAVNRGDQ----------------------TLKEAVDTLQK
LSVFDAEVQAARDKARAALEDIGIIGQLIREATQKSEDIHQILDGSEQNAIRAREVAQQA
QA-------NANNASAMANEIHQEANKTKAEVIKLGNEADKLHLRVNTTDNMIRQYEDRI
RKDADNTAQAKVKVSQAKSNVTSA----GQQVT-KALEEIAEITR--------ELDALP-
--DISNADLDRLEDRLRKAEDDIRAA---------DLDQRIRA----------------L
TDSK----NLQTQWVKNYEDEVSRLRVEVENINDMKKVLPSH--CYNNPRLEP-
>gi|114568350|ref|XP_001162731.	Pan troglodytes
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------MPALWLG-----
------------------------------------------------------------
----------------------------------------CCL-----------------
-----------------------------------------------CFSLLL-------
PAARA------------TSRREVCDCNG--KSRQCIFDRELHRQTGN--GFRCLNCNDNT
DGIHCEK------CKNGFYRHRERD-------RCLPC----NCNSKGSLSAR--CD--NS
-------GQCSCK-PGVTGARCDRCLP---GFHMLTD---AGCTQ--DQRLPDSKCDC-D
PAGI-------------------------------------AGPCDA--GRCVCKPAVT-
----------------GERCD------R---CRSGYYNLDGGNPE----------GCTQC
----------FCYGHSASCRS--------------------------------SAEY-SV
HKITSTFHQDVDGW-------------KAVQRNGSPAK------LQWSQRHQDVFSSAQR
LDPVYFVAPA--KFLGNQQVS-YGQSLSFDYRVDRG----GRHPSAHDVILEGAG---LR
ITAPLMPLGKTLPCGL-------------------TKTYT--FRLNEHPSSNWSPQLSY-
--FEYRRLLRNLTALRI--------------RATYGEYS---------------------
TGYIDNVTLISA----RPVSGAPAPWVEQCICPVGYKGQFC------QDCASGYKRDSAR
-------LGPFGTC----------------------------------IPCNCQGGG-AC
---------DPDTGDC-YSGDENPDIEC----ADC-------------------------
--PIGFYNDPHDPRS------------C-------KPC---------PCHNGFS------
-------------CSVMPETEEVVCNNCP-----PGVTGARCE-----------------
---------------------------------LCADGYFGDPFGE--------------
------------------------------------------------HGPVRPCQP-CQ
CNNNVDPSASGNCDQLTG------RCLKCIHNTAGIYCDQCKAGY-FG-DPL--------
---APNPAD---------------------------------------------------
------------------------------------------------------------
---------------KCR------------------------------------------
--------------------------------ACNCNPMGSEPVGC-----RSDGTCV--
CKPGFGGPNCEHG-EFS--------------CP-ACYNQVKIQMDQFMQQLQRMEALISK
AQGGDGVVPDTELEG---RMQQAE-------------QALQDILRDAQISEGASRSLGLQ
LAKVRSQENSYRSRLDDLKMTVERVRALGSQYQNRVRDTHRLITQMQLSLAESEASLGNT
NIP--ASDHYVGPNGFKSLAQ-------------------EATRLAE-SHVESASNMEQL
TRET-------EDYSKQALSLVRKALHEGVGSGSGSPDGAVV-------------QGLVE
KLEKTKSLAQQLTREATQAEI----------EADRSYQHSLR-----------LLDSVSR
LQGVNDQSFQVEEAKRIKQKADSLSSLVTRHMDEFKRTQK-NLGNWKEEAQQLLQNGKSG
REKSDQLLSRANLAKSRAQEALSMGNA----------------------TFYEVESILKN
LREFDLQVDNRKAEAEEAMKRLSYISQKVSDAGDKTQQAERALGSAAADAQRAKNGAGEA
LE-------ISSEIEQEIGSLNLEANVTADGALAMEKGLASLKSEMREVEGELERKELEF
DTNMDAVQMVITEAQKVDTRAKNA----EVTIQ-DTLNTLDGLLH--------LMDQPV-
--SVDEEGLILLEQKLSRAKTQINSQ----------LRPMMSE----------------L
EERA----RRQRGHLHLLETSIDGILADVKNLENIRDNLPPG--CYNTQALEQQ
>gi|118093037|ref|XP_001233267.	Gallus gallus
------------------------------------------------------------
---------------------------------------------------------MAP
AGSAEPGS--------------------------------ALSRAGAA-----PPPLGAW
RPFP-----------------------SACCCCFSAL-----------------------
---------------------------------------LDVNSWLLFYGFLYLALYAQV
S--QSKSCDKI---------------SCFSGHCV--NSTCV-------CDQGWVGDQCQ-
-----------------HCQGRFKLTEPSG--YL------------TDGPINYKY---KT
KCTWLIEGY---------------PNAILRLRFNHFATE-CSWDHMYVYDGDSI------
-------------YAPLIAVFSGLIVPE----VRGNETVP-EVVTTSGYALLH--FFSDA
AYNLT-GFNIFYSINSCPN-----NCSE---------------------HGKCTTSLSIP
SRVYCE-------CDKYWKGEACDI-------PYCKA----NC---GSPD-HGYCDLTGE
-------KLCVCN-DSWQGPDCSLNVPSTESYWIL-----PNVKPFSPSVGRASHKAV-L
HGKFMWVIGGYTFNYSSFQMVLNYNLESSIWNVV-----PVSKGPLQRYGHTLALYQED-
------------IYMYGGKIET-----NNGNVTDELWIFNIHSQAWSIRTPAVL-VHGQQ
---------YAVEGHSAHIVE------------LDSR------DVVMIIIFGYSAIY-GY
TSIVQEYYIRSNSW-------------LVPETKGAIVQGGYGHTSVYDELTKSVYVHG--
-GYKALPGNK--YGLVDDLYK-YEVNTRTWTILKES----GFARYLHSAVLIN-G---AM
LIFGGNTHNDTSLSNG-------------------AKCFSADFLAYDIACDEWKILPKP-
---NLHRDVNRFGHTAV---------VSNGSMYIFGGFS---------------------
SVLLNDILVYKP--------PNCEAFRDEELCKNARPGIRCLWN--KKHCESWESGNAN-
-------NILRAKC------------------PKKTG--------KSYDRCYRYADCASC
---------TANTNGCQWCD----DKKCISANSNC-------------------------
--SMEQVSVKNYTKCHVRNE----QI-CNKL----TSC--------KSCSLHLN------
-------------CQWDQRQQECQALPAHLCGEGWSHIGDACLRINSSRESYDNAKLYCY
NLSGNLASLTTSKEVEFVLDEI---QNSQTLEKLKISPWVGLRKINISYWGWDDMSPFTN
TTLQWLPGEPNDSGFCAYLERAEVAGLKANPCTAMADGLVCEKPVVSPNQNARPCKKPCS
LRTS-----CSNCTSNGM------ECMWCSSTKRCVDSNAYIISFPYG-QCL--------
---EWQTAT--C--------------------SPQN---C---SGLRTCGQCLEQPGC--
GW--------CNDP-----SNTG--KGQCLEGSSRGPMKP-----VGMHSAEMVLDATLC
PK-EKSYEWSFI---QCP------------------------------------------
--------------------------------ACQCNGHST----C-----INSNVCDQ-
CKNLTTGKQCETCMPGY-YGDPTN-GGQCTAC--TCSG--HANICHM-------------
------------------QTGKCF-------------CTTKGIKGDQCQLC---------
--------------------------------------------------DSENRYLGNP
L-R--GTCYYSLLIDYQFTFSLLQEDDRHH----------TAINFIA-NPEQSNKNLDIS
INAS----------NNFNLNITWSI-----GSTAGTISGEEI-------------PVVSK
ANIKE--YRDSFSCEKFNFRS----------NPNI---TFYV-----------YVSNFS-
-WPIKIQ-----------------------------------------IAFSQHNTIMDL
VQFFVTFFSCFLSLL-LVAAVVWKIKQ----------------------TCWASRRREQL
MRERQQMASRPFASVDVALEVGA-------------EQTDFL-----------RGPLEGA
PK----------------------------------------------------------
----------------------------PIAIE-PCSGNKAAVLT--------VFLCLP-
--R----GSSGVPPPGQS-GLAIASA---------------------------------L
IDIS----QQKPTECK---DKSSGVRNRKHHLSTRQGT------CV--------
>gi|118404388|ref|NP_001072726.	Xenopus tropicalis
------------------------------------------------------------
------------------------------------------------------------
-----------------------------------------------------MVHSLKW
LGIFP-------------------------------------------------------
---------------------------------------LILFQWLGTTSSLNLEDPNVC
SHWESYSVTVQ---------------ESYSHPYDQVYYTS--------CTDILNWFKCT-
---------------------RHRISYRTA--YR------------RGEKTMYRR---KS
QCCPGFYES-------------------REMCVPHCADK-CV------------------
-------------HGRCIA-------------PNTCQCEP-GWGGPNCSSACDVDHWGPH
CSSRC----QCKNGALCNPITGACHCSSGYKGWRCEERC---DQGTY--GNDCQQKCQCQ
NGASCDHVTGECRCPPGYTGAFCED-------LCPPGKHGSQCEERCPCQNGGVCHH-VT
-------GECSCP-AGWMGTVCGQPCP--EGRYGR------NCSQ---------ECQC-H
NGGT----------------------------------------CDSATGQCYCSPGYN-
----------------GERCQ------EE--CPVGLYGVKCAQTC----------QCLNG
---------GKCYHISGACLCEPGYTGERCETPLCSE------GTYGMKCDKKCPCH---
LQYTQSCHPMSGEC-------------ACKP----------GRSGLYCNETCSLGFYG--
-EFCQQICSC--QN-----GA-DCDSVTGKCICAPG------FTGVDCSTACPPGTYGVN
CSSLCNCKNNAVCSPV-------------------DGSCTCKAGWHGVDCSINCPRGSWG
LGCNLTCQCLNGGACNPLDGTCTCAPGWRGLKCELPCQD---------------------
GTYGMNCIERCD----CSHADGCHPATGYCRCLAGWAGMHC------DSVCPG-------
-------GHWGPNC---------------------------------SLSCDCKNGA-SC
---------SPDDGICE-CAPGYRGTTC---QRIC-------------------------
--SPGFYGHRCSQACP--------------------QC----------VHSNGP------
-------------CHHVTGQCDCL----------AGFMGSLCN-----------------
--------------------------------EVCPSGRYGKN-----------------
------------------------------------------------------CAGVCA
CTNN------GTCNPIDG------TCQ-CYPGWIGNDCSQACPPGHWGPNCI--------
---------HTC--------------------NCHNGAYCSAYDGECKCSP---------
GWTGLYCTQRCPLGYY---GKECTLVCQCQNGADCDHI-------TGQCTCRTGFMGKFC
EQKCPSASYGY----GCRQ-----------------------------------------
--------------------------------VCDCLNNST----C----DHITGTCY--
CSPGWKGARCDQAVMIV-VGNLNSLSRTSAAIPADSYQ--IGAIAGIII-----------
------------------LVLVVL-------------FLLALFIIYRQKQK---------
----------------GKDTAMPAVAYTPAVRVLSTDYTIADTLPHNNVVNANSQYFSNP
SYHTLSQCTTGPQVNSMDRMMVSRSKSSQL-----------FVNLKNLDPGKRSHTIDYT
GTLP----------------ADWKQ-----GGFLN-------------------------
-------ENGLLKNSAYSIST----------CSLSSTENPYA-----------TIKDP--
-PVLLPKNIECGYVEMKSPARRDSAYAEISNSS---------------LANKNVYEVEPT
VSVVQGAFCNNGKI-----------SQ----------------------DLYDLPKNSHI
------------------------------------------------------------
------------------------------------------------------------
----------------------------------PC-----------------HYDLLP-
--V---------------------------------------------------------
---------------------RESSSSNKDESTSE-------------------
>gi|50979208|ref|NP_001003351.1	Canis lupus
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-----------------------------------------------------------M
PALWLR----------------------------------C-------------------
----------------------GL-----------------------CLALLL-------
PAARA------------SSGSQVCDCNG--KSRQCVFDQELHRQTGN--GFRCLNCNDNT
DGPRCEH------CKDGFYRQRERD-------RCLPC----NCHTKGSLSAR--CD--NS
-------GRCSCK-PGVTGDRCDRCLP---GFHTLTD---AGCTQ--DQRLLDPKCDC-D
PAGI-------------------------------------SGPCDE--GRCVCKPAVT-
----------------GERCD------R---CRPGYYHLDGGNPE----------GCTQC
----------FCYGHSANCHS--------------------------------SGDY-SV
HKITSTFHQDVDGW-------------KAIQRNGSPAK------LQWSQRHRDVFSSARR
SDPVYFVAPA--KFLGNQQVS-YGQTLSFDYRVDRG----GRHPSAHDVILEGAG---LR
VTAPLMPRGKTLPCGI-------------------TKTYT--FRLNERPSSQWSPQLSY-
--FEYRRLLRNLTALRI--------------RATYGEYS---------------------
TGYLDNVTLISA----RPVSGAPAPWVEQCVCPVGYKGQFC------QDCASGYKRDSAQ
-------LGPFGTC----------------------------------IPCNCQGGG-AC
---------DPDTGDC-YSGDENLDIEC----ADC-------------------------
--PIGFYNDPHDPRS------------C-------KPC---------PCHNGFS------
-------------CSVMPETEEVVCNNCP-----HGVTGARCE-----------------
---------------------------------LCADGYFGDPFGE--------------
------------------------------------------------RGPVRPCQP-CQ
CNNNVDPSASGNCDRLTG------RCLKCIYNTAGVHCDQCKAGY-FG-DPL--------
---APNPAD---------------------------------------------------
------------------------------------------------------------
---------------KCR------------------------------------------
--------------------------------ACNCNPAGSEPGEC-----RSDGSCV--
CKPGFGGLNCEHAALTS--------------CP-ACYNQVKIQMDQFMQQLQSLEALVSR
VQGGGGAVPDAELEG---RMQQAE-------------QALQELLREAQISEGASKSLSLQ
LVKARREEESYRNRLDDLKMMVERIRALGSQYQNRVQDTRRLVTQMQLSLEESTASLRNT
NIP--SSDHYVGPNGFKSLAQ-------------------EAVRLAD-SHVASASNMERL
VRET-------EDYSKQALALAHKALREGGGSGGGGGGGSDGSAA----------QGLMG
RLAKARSLAQQLSGEAAQADA----------EADRSYQRGLR-----------LLDAASQ
LQQVSGRACQVE-MKRIRQNIDSLSSLVTRRMDEFKHVQS-NLGNWEEETQQLLRNGKSG
RQKADQLLSRANLAKSRAQEALSMGNA----------------------TFYEVENILKN
LREFDLQVEDRKAEAEEAMKRLPYISQKVADASDKTRQAETALGGAAADAQRAKTAAREA
LE-------ITDKIEQEIGSLNLEANVTADGALAMEKGLATLKSDMREVEGELARKEQEF
DLDMDAVQMVITEAQRVDNRAKNA----GATIQ-DTLNTLDSILH--------LINQPG-
--SVDEEKLILLEQNLFRAKTQINSQ----------LRPLMSE----------------L
EERA----RRQQGHLHLLETSIDGVLADVKNLENIRDNLPPG--CYNTQALEQQ
>gi|34534123|dbj|BAC86914.1|	Homo sapiens
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
---------------------------------------------MYVYDGDSI------
-------------YAPLIAVLSGLIVPE----IRGNETVP-EVVTTSGYALLH--FFSDA
AYNLT-GFNIFYSINSCPN-----NCSG---------------------HGKCTTSVSVP
SQVYCE-------CDKYWKGEACDI-------PYCKA----NC---GSPD-HGYCDLTGE
-------KLCVCN-DSWQGPDCSLNVPSTESYWIL-----PNVKPFSPSVGRASHKAV-L
HGKFMWVIGGYTFNYSSFQMVLNYNLESSIWNVG-----TPSRGPLQRYGHSLALYQEN-
------------IFMYGGRIET-----NDGNVTDELWVFNIHSQSWSTKTPTVL-GHGQQ
---------YAVEGHSAHIME------------LDSR------DVVMIIIFGYSAIY-GY
TSSIQEYHISSNTW-------------LVPETKGAIVQGGYGHTSVYDEITKSIYVHG--
-GYKALPGNK--YGLVDDLYK-YEVNTKTWTILKES----GFARYLHSAVLIN-G---AM
LIFGGNTHNDTSLSNG-------------------AKCFSADFLAYDIACDEWKILPKP-
---NLHRDVNRFGHSAV---------VINGSMYIFGGFS---------------------
SVLLNDILVYKP--------PNCKAFRDEELCKNAGPGIKCVWN--KNHCESWESGNTN-
-------NILRAKC------------------PPKTA--------ASDDRCYRYADCASC
---------TANTNGCQWCD----DKKCISANSNC-------------------------
--SM---SVKNYTKCHVRNE----QI-CNKL----TSC--------KSCSLNLN------
-------------CQWDQRQQECQALPAHLCGEGWSHIGDACLRVNSSRENYDNAKLYCY
NLSGNLASLTTSKEVEFVLDEI------QKYTQQKVSPWVGLRKINISYWGWEDMSPFTN
TTLQWLPGEPNDSGFCAYLERAAVAGLKANPCTSMANGLVCEKPVVSPNQNARPCKKPCS
LRTS-----CSNCTSNGM------ECMWCSSTKRCVDSNAYIISFPYG-QCL--------
---EWQTAT--C--------------------SPQN---C---SGLRTCGQCLEQPGC--
GW--------CNDP-----SNTG--RGHCIEGSSRGPMKL-----IGMHHNEMVLDTNLC
PK-EKNYEWSFI---QCP------------------------------------------
--------------------------------ACQCNGHST----C-----INNNVCEQ-
CKNLTTGKQCQDCMPGY-YGDPTN-GGQCTAC--TCSG--HANICHL-------------
------------------HTGKCF-------------CTTKGIKGDQCQLC---------
--------------------------------------------------DSENRYVGNP
L-R--GTCYYSLLIDYQFTFSLLQEDDRHH----------TAINFIA-NPEQSNKNLDIS
INAS----------NNFNLNITWSV-----GSTAGTISGEET-------------SIVSK
NNIKE--YRDSFSYEKFNFRS----------NPNI---TFYV-----------YVSNFS-
-WPIKIQ-----------------------------------------IAFSQHNTIMDL
VQFFVTFFSCFLSLL-LVAAVVWKIKQ----------------------TCWASRRREQL
LRERQQMASRPFASVDVALEVGA-------------EQTEFL-----------RGPLEGA
PK----------------------------------------------------------
----------------------------PIAIE-PCAGNRAAVLT--------VFLCLP-
--R----GSSGAPPPGQS-GLAIASA---------------------------------L
IDIS----QQKASDSK---DKTSGVRNRKHLSTRQGT-------CV--------
>gi|16930101|dbj|BAB72012.1|	Mesocricetus auratus
------------------------------------------------------------
--------------------------------------------MVAAAAATEALLRGST
AATAAPAG--------------------------------RKVEQYRL-----CAATGAW
RPGP-----------------------RAGLCLPWVVSRAL-------------------
----PPPLLLLLLLFS---LLL-----------------LPLPREAEAAAVSAAVSGSAA
A--EAKECDRP---------------CVNGGRCNPGTGQCV-------CPAGWVGEQCQ-
-----------------HCGGRFRLTGSSG--FV------------TDGPGNYKY---KT
KCTWLIEGQ---------------PNRIMRLRFNHFATE-CSWDHLYVYDGDSI------
-------------YAPLIAAFSGLIVPE----RDGNETAP-EVTVTSGYALLH--FFSDA
AYNLT-GFNITYNFDMCPN-----NCSG---------------------RGECKSSNS-S
NTVECE-------CSENWKGESCDI-------PHCTD----NC---GFPH-RGICNASDV
-------RGCSCS-PHWQGPGCSIPVPANQSFWIR-----EEYSD--FKLPRASHKAV-V
NGNIMWVVGGYMFNHSDYSMVLAYDLASREWLPL--N--HSVNNVVVRYGHSLALHKDK-
------------IYMYGGKID------STGNVTNELRVFHIHNESWVLLTPKAK------
-------EQYAVVGHSAHIVT------------LATG------RVVMLVIFGHCPLY-GY
ISIVQEYDLEKNTW-------------SILQTQGALVQGGYGHSSVYDHRTKALYVHG--
-GYKAFSANK--YRLADDLYR-YDVDTQMWTILKDS----RFFRYLHTAVIVS-G---TM
LVFGGNTHNDTSMSHG-------------------AKCFSSDFMAYDIACDRWSVLPRP-
---DLHHDVNRFGHSAV---------LHNSTMYVFGGFN---------------------
SLLLSDVLVFTS--------EQCDAHHSEAACVAAGPGIRCLWDTVSSRCTSWELATEEQ
A------EKLKSEC------------------FSKRT--------LDHDRCDQHTDCYSC
---------TANTNDCHWCN-----DHCVPVNHSC-------------------------
--TEGQISISKYDNCPKDNP----MYYCNKK----TSC--------RSCALDQN------
-------------CQWEPRNQECIALPENICGIGWHLVGNSCLKITTAKENYDNAKLSCR
NHNAFLASLTSQKKVEFVLKHLRLMQSSQSMSKLTLTPWVGLRKINVSYWCWEDMSPFTN
SLLQWMPSEPSDAGFCGILSEPSTRGLKAATCINPLNGSVCERPA---NHSAKQCRTPCA
LRTA-----CSECTSSSS------ECMWCSNMKQCVDSNAYVASFPFG-QCM--------
---EWYTMSS-C--------------------PPEN---C---SGYCTCSHCLEQPGC--
GW--------CTDP-----SNTG--KGKCIEGSYKGPIRMPSQASTGNVYPQPLLNSSMC
LE-DSRYNWSFI---HCP------------------------------------------
--------------------------------ACQCNGHSK----C-----INQSICEK-
CENLTTGKHCETCISGF-YGDPTN-GGKCQPC--KCNG--HASLCNT-------------
------------------NTGKCF-------------CTTKGVKGDECQLC---------
--------------------------------------------------EVENRYQGNP
L-K--GTCYYTLLIDYQFTFSLSQEDDRYY----------TAINFVA-TPDEQNRDLDMF
INAS----------KNFNLNITWAT-----SFSAGTQAGEEM-------------PVVSK
TNIKE--YKDSFSNEKFDFRN----------HPNI---TFFV-----------YVSNFT-
-WPIKIQ-----------------------------------------IAFSQHSNFMDL
VQFFVTFFSCFLSLL-LVAAVVWKIKQ----------------------SCWASRRREQL
LREMQQMASRPFASVNVALETDE-------------EPPDLI-----------GGSIKTV
PK----------------------------------------------------------
----------------------------PIALE-PCFGNKAAVLS--------VFVRLP-
--R----GLGGIPPPGQS-GLAVASA---------------------------------L
VDIS----QQMPIVYK---EKSGAVRNRKQQPPAQPGT------CI--------
>gi|157019474|gb|EAA05420.4|	Anopheles gambiae
------------------------------------------------------------
------------------------------------------------------------
-----------------------------------------MVGGRPA-----SPHSSVW
R--------------------------LVL------------------------------
-----------LVLL------------------------ALSCQLGPTVLVSSHGLAGVA
D--PGKCSEVR---------------CMNGGVCK--NGTCL-------CPDGWQGSECQ-
-----------------FCGGKVRLTEPSG--SI------------HDGLGNYSI---GV
KCSWLIDAREHNSITDKVS-TEPGRPSVIRLHLEEFATE-CGWDHLYVYDGDSV------
-------------ESPLLAVFSGLMYRK----NFTIRRIP-EVFAHSGSALLH--FFSDD
AYNMS-GFNISYQVNACPTNDSSLNCSG---------------------NGDCWNGE---
----CS-------CNSGFTGAACNI-------PRCPN----YC---SAHLGRGVCDR-KQ
-------QRCVCS-AGYTGNDCSQAIA--HGYWTAID---AGETEGFTPPGSASHGAA-V
FHDTLYVIAGESYGKAE-ALLYMYDFNGKVWETA--HT-ESRPAPELRYGASTVIFGDK-
------------IFMYGGVIE------GR-GVCGELWAFDVSAKIWENITVKAE-QCNDT
---YEMCGPLRSAGHTATIVSNYDQVGGKKVLTGGGS------SQKMVVIFGHSPQF-GY
LNTVQEFNFGTREW-------------RIVPTRGYPVKGGYGHSAAYDPLRERIYVYG--
-GIVSESDSS--QLLSNKLYS-YEPHERLWTLLETA----PTARFLHTANFLTPG---LM
MVFGGNTHNDTSHSFG-------------------AKCYSRDLMVYDVLCDSWHAQPMP-
--DDLYADLARFGHSAV---------VFERSLYVYGGFD---------------------
GQMVNDMLQFTP--------GDCQAFNRTDQCLNARPGVKCVWDIQKSRCLPAAAVQRER
LFDRD--QEGLEVC------------------PKKSRLVMTQHELMDYELCSQLTTCQGC
---------VSTAYGCMFCGIGNGKGIC--VKEKC--------------------PDVSY
TYRADFYPTKALKDCPDNDE----HV-CAQL----HGC--------HACTAVSV------
-------------CHWDYEH-------------------SRCQ-----------------
--------------------------------------YSRNKSGDA-------------
------------------------------------------------LNDA--CPPACS
GLTS-----CGNCTQE--------ECIWCQNEQRCVDKNAYTASFPYG-QCR--------
---EWTTGSSKCRAASS---------------GKSQ---C---GFYRTCAQCRDDPAC--
GW--------CDDG-----SLTG--LGKCLPGGDSGA-----------------HEESEC
PA-QR---WHFT---HCP------------------------------------------
--------------------------------SCQCNGHST----C-----PDAKTCKQP
CSNLTFGPNCDKCKPGF-WGNPVN-GGICQKC--ECNG--QAQYCHS-------------
------------------ETGKCF-------------CSTKGLAGDHCEKC---------
--------------------------------------------------DATNHYHGDP
S-R--GSCYYDLTIDYQFTFNLSKKEDRHF----------TQINFRN-SPVKPDIDADFT
ITCS----------VAARMNITIRT-----AGGIEK-------------------PLFSA
VNCST--FRYRFSKAEHQFGV----------EDNVTLTTFYV-----------YVYDFQ-
-PPLWIQ-----------------------------------------IAFSQYPK-LNL
QQFFITFSTCFLLLL-VMAAILWKIKQ----------------------HYDMFRRRQRL
FVEMEQMASRPFSQVLVEIESR--------------EYNELSPAVENITAAP-RKRKKDS
PS----------------------------------------------------------
----------------------------PIALE-PCEGNRAAVLS--------LLVRLP-
--T----GGLQHSPPGQSAGLAVASA----------------L----------------V
TLGN----PRRSSIE----HPKEP-KTKRKQSQHPDS-------CI--------
