>gi|149411717|ref|XP_001509741.	Ornithorhynchus anatinus
------------------------------------------------------------
-----MPGKRAASAASG------EEFSFVNPVVK-YLLFFFNMLFW-VIAIVLVGVGVYA
RLMKH-------AETAMACL-AVDPAILLITVGILMFLLTFCGCIGSLRENICLLQMFSV
CLTVVFLLQLAAGVLGFVFSD--KARGKVSEIINKAIVH-YRDD--LDLQNLIDFGQKE-
FNCCGG----VSYKDWSRNLYFN-CTDDNP-SRERCSVPFSCCLH-----------VPD-
-QTVINTMCGQGMQSLDYLEA-----GEVINTNGCIDKLVNWIHSNLFLLGGLALGLVIP
Q-----------------------VNLVLRTILINQIKDQVRLQFYNQQ-----------
------------------------------------------HRADPWN-----------
---------------------------------------------------------
>gi|157020789|gb|EAA03776.4|	Anopheles gambiae
---------------------------------------------------------KQQ
QQQHRRSHTMPPYRYPT------HNFTYVSSCVK-YMIFLLNFIFW-LFGGLLIGIGFYA
FVDKWQ-ATGLIKLETFYDI-VLNLSLVMIIAGAIVFVVSLAGCLGALRENTCLLKFYSL
CLLIFFLCEMAIAITAFVFPH--KVNAVLEESFTDKIITTYRDD--PDLQNLIDFAQQE-
FHCCGLS--NEGYLDWGKNEYFN-CSSPSV---EKCGVPYSCCIN-----------ATDI
SSGLVNIMCGYHIQQQSVAAA-----SKKIWTNGCIEIVRVWAERNLYVIAGIALGAAIS
Q----------------------LFVIYLAKTLEGQID----------------------
------------------------------------------LQKSSWS-----------
---------------------------------------------------------
>gi|109510117|ref|XP_001056482.	Rattus norvegicus
-----MRVKLYEERSTRLQEPVPEPREMDKAFLGAQGNRIYRDQQCHAGNPPCAALRLLR
STSASIVSLELTMKSSS------ACRSQISCFLDAHLQAPWELMFVPLIGGLVLSVGIYA
EAERQ-------KYKTLESA-FLAPAIILILLGVVMFIVSFIGVLASLRDNLCLLQSFMF
ILGLCLVMELIGGIVALIFRN--QTIDFLNDNIRRGIEN-YYDD--LDFKNIMDFVQKK-
FKCCGG----EDYRDWSKNQYHD-CSAPGP---LACGVPYTCCIR-----------NT--
-TDVVNTMCGYKTIDKERLNA-----QNIIHVRGCTNAVLIWFMDNYSIMAGLLLGILLP
Q----------------------FLGVLLTLLYITRVEDII-LEHSVTDGLLGPGAKSST
DTAGTGCCLCYPD-----------------------------------------------
---------------------------------------------------------
>gi|109068176|ref|XP_001091336.	Macaca mulatta
-----------------MAGYSVTSATSQWEVGLQPSRQWASGGGPGFLGAGLAGLVLRP
QLSLRRSRCPPRLRRLQAPAASGEEFSFVSPLVK-YLPFFFNMLFW-VISMVMVAVGVYA
RLMKH-------AEAALACL-AVDPAILLVVVGVLMFLLTFCGCIGSLRENICLLQTFSL
CLTAVFLLQLAAGILGFVFSD--KARGKVSEIINNAIVH-YRDD--LDLQNLIDFGQKK-
FSCCGG----ISYKDWSQNMYFN-CSEDNP-SRERCSVPYSCCLP-----------TPD-
-QAVINTMCGQGMQAFDYLEA-----SKVIYTNGCIDKLVNWIHSNLFLLGGVALGLAIP
Q----------------------LVGILLSQILVNQIKDQIKLQLYNQQ-----------
------------------------------------------HRADPWY-----------
---------------------------------------------------------
>gi|91077194|ref|XP_972823.1|	Tribolium castaneum
------------------------------------------------------------
---MAVNLPTMPVRKYR------RETSEVSSCLK-YMIFGFNVLFW-LLGLGILTVGVWA
WSEKD----IFNNLGKVANV-ALDPAFILICIGTVTFIIGFTGCVGALRENTCLLATYAI
FLSVLLLFEMTAGILGFIFKD--WIKSQATIGFQTFIIH-YRED--PDQQNLIDWIQEDW
LQCCGI----EGPKDWDRNNYFN-CSSRDVGSREACGVPFSCCKR-----------KPN-
-EIIKNKQCGYDVRK-PGFPG-----ERHIFERGCLRAGEEWIESNLVPVAAVKVGIMVL
Q----------------------NFDV---SKIINEKGCLEAIEEWLERNMISLATFGFI
ILFLQILGICFAQNLRADIF----------------------AQKAKWH-----------
---------------------------------------------------------
>gi|89271865|emb|CAJ82249.1|	Xenopus tropicalis
------------------------------------------------------------
------------MHYYR------YSTAEVSCCYK-YLLFSYNIIFW-LSGMVLLGVGLWA
WSEKG----ILSDITKVTRLHGFDPVWLVLVVGVIMFTLGFAGCVGALRENICLLKFFCG
AIVLIFFMELAVAVLAFLFQD--WVKDRAKDFFENNIKS-YRDD--IDLQNLIDSLQKA-
NQCCGA----VSPDDWDLNEYFN-CSVENP-SRERCGVPFSCCVP-----------DPA-
-QTVVNTQCGYDARRKKPNER-----PNTTFSKGCISALEAWLPRNIYIVAGVFLVISIL
Q----------------------IFGIYLARTLMSDIEAVKAGYRFLRATLIVQRHYRDF
LYFFPSFKSLFAVRDFSTLPLS--IKICRV---------STFAQKDPL------------
---------------------------------------------------------
>gi|50757911|ref|XP_415703.1|	Gallus gallus
---------MVLGREQLSQFFRPYGEVGSGESSRLLPQTSQLAELPQSSDDDDDISLLGG
ADDPVAKHDTEEWCKP----------SAFSHCVR-HLAFLWNLLFL-LLGLLTLGIGVWG
LLAKG-----WLQGERSAPL-GSDPMLLFVLAGLGASTVSLAGCLGVLRSSTCLLRFFVG
AVLAFVGLEVLGGLLLLVARQ--RLRDALQDALLLCLLR-YQEE--PDLRFLVDEVQRS-
LRCCGL----SSYRDWESNPYFN-CSAPGV---QACSVPASCCL------------DPWQ
NGSITNDQCAFGVLHLGDVAA-----AGVVHLGGCVVQLGAWLRGQAGGIATGAAVLVLL
E----------------------ATGLLLVLKVLADIV----------------------
------------------------------------------PGGARG------------
---------------------------------------------------------
>gi|72142201|ref|XP_787272.1|	Strongylocentrotus purpuratus
----------------------------------------------MGKKTQPYPQPASS
QQQLHYHQPPPARVRRA------PHGITVSICVK-YTIFAFNVIFW-LCGLGILAFGVWG
LVSKS--VSSVEAIAEEVGI-KLDPMYGFIIVGGCIFILAFLGCIGSLRENTCLLKLYVI
ILVLIFLAEITIGLLVYFYQD--RFVTLLDTWVEKTLLN-YFDD--PDSQFLMDNMQEG-
LTCCGV----NSPDDWQKNAYFN-CSSIAD---SRCSVPFSCCVP-----------DPT-
-TSVINYQCGYGVLALPPTEW-----FMTIYTIGCAQSLTDWFKTNVILLSCIGGALVLM
Q----------------------SIAICLARSLIGDVK----------------------
------------------------------------------EVKSYW------------
---------------------------------------------------------
>gi|122891272|emb|CAM14398.1|	Danio rerio
------------------------------------------------------------
---------MPSYEEWR------KTIHFY-YFLK-FSLNVYSMLFS-LLGLCVLCIGVYA
EVERQ-------KNRTLEGV-FLAPAVVLILLGLVMFTVSVIGMVGSLRDNKTLLHMFLC
VLCVLLALQAIALIIALIFEK--TTIKLFQNSIREGIKH-YYDD--LDFKNILDYVQEK-
FSCCGG----DEYKDWEVNQYHL-CDGKSP---LACGVPYTCCIR-----------QSV-
-GEVVNTLCGYKTLHQQREAL-----DGVIHVRGCIHAVNLWMGDNIGATIGICCAVGLP
Q----------------------LLGILLSCVFWNLLVEMSESQDMVDFKFLKRAGYKYS
ELDLSGAGWCMCLPREEGYLPV--PVGEPD---------TWAPDPIPYYQEQEFTHSQLE
SKGPHSGMGMDEVDNRA----------------------------------------
>gi|56757528|gb|AAW26928.1|	Schistosoma japonicum
------------------------------------------------------------
--MSIHSMGRRYHRGFT------GRISYINQWVK-YSLCLANFIFL-TIGTVFLVFGAIA
FIESG--GIPWKSNITALQW-LFNLTVICTGVGIITLFVSLAGFIGSLRENNCLLKFYYS
ILTLLFLTEVICCVLFFVYRE--SAIRKLEELIKTTFVTQYRELGFEDTTNFMDFIQKE-
LNCCGP----KSYLDWTANRYFS-CNKSNV-SPEACGVPYSCCRQ-----------MNNI
NINVINTSCGFGVQKSTTAVA-----SRLVWTTGCVQALINVVESNIVHFACGVSGVAVL
Q----------------------LLAILLAKTLHTQISDQLRL-----------------
------------------------------------------LRQENIHF----------
---------------------------------------------------------
>gi|114670939|ref|XP_511737.2|	Pan troglodytes
-----------MEEGERSPLLSQETAGQKPLSVHSPPTSGCLGPVPREDQAEAWGCSCCP
PETKHQALSGTPRKGPA------PSLSPGSNCVK-YLIFLSNFPFS-LLGLLALAIGLWG
LAVKG-----SLGSDLGGPL-PADPMLGLALGGLVVSAVSLAGCLGALCENTCLLRGFSG
GILAFLVLEAVAGALVVALWG--PLQDSLEHTLRVAIAH-YQDD--PDLRFLLDQVQLG-
LRCCGA----ASYQDWQQNLYFN-CSSPGV---QACSLPASCCI------------DPRE
DGASVNDQCGFGVLRLDADAA-----QRVVYLEGCGPPLRRWLRANLAASGGYAIAVVLL
Q----------------------GAELLLAARLLGALAARRGAAYGPGARGEDRAGPQSP
SPGAP-------------------------------------PAAKPARG----------
---------------------------------------------------------
>gi|156539613|ref|XP_001599019.	Nasonia vitripennis
------------------------------------------------------------
----------MNNRRRT------NNFTYVSSCVK-YMIFMLNFIFW-LFGGLLIGVGLYA
FVDKWQ-MTGSVRVENVYDI-VLNISLVMIIAGAVVFIVSFAGCVGALRENTCLLKFYSL
CLLIFFLLEMGVAIVGFVFPH--TLQSLLEESFTDKIIQTYRED--PDLQNFIDFGQKE-
FKCCGLS--QIGYLDWGKNEYFN-CSSPSS---EGCGVPFSCCIN-----------DTNI
ASRLVNNMCGNGVQKTPVSEA-----SKKVWTSGCIEIVRAWAERNLYTIAGIALGIALS
Q----------------------LFVIYLAKTLEGQIE----------------------
------------------------------------------LQKSRWHS----------
---------------------------------------------------------
>gi|78214206|gb|ABB36425.1|	Drosophila melanogaster
-----------------------------------------SHGHTGEQNFIRLCFLLAI
FIIVKIGAMPAAVRKFR------RETSEISCCLK-YLLFASNVILW-LSALLVLSVGIWA
WSEKG----MFRNIARLHFI-ALDPAFVLIILGGVTFLLGFMGSVGALRENTCLLGAYAI
FLSVLLIAEIGFCAVAFVLKDKGWIKDQATEGLKAFIRH-YRED--ADQQNLIDWIQEDW
LQCCGI----DGPKDWDSNNYFN-CSSIAIGSREACGVPFSCCRR-----------RPQ-
-EVIKNKQCGYDVRK-EGYPV-----DRNIHERGCLRAGEDWLEAHLISVAIGCVALLVL
Q----------------------GMEL---SKIIYEKGCVQAGEEWMEHNLIIISATVIV
VMFFQILGICFAQNLRADIY----------------------TQKSKWH-----------
---------------------------------------------------------
>gi|119912660|ref|XP_875180.2|	Bos taurus
------------------------------------------------------------
--------MGPPTFSTP------LFFTWVSSCLK-CLLFLSNFLFS-LLSLLALAIGLWG
LAVKG-----SLGSSWGSPL-PADPMLGLVLGGLAVSVVSLAGCLGALCENTFLLRCFSG
GVLAFLVLEAVVGALVVALWG--QLQDGLEHVLRLAITH-YQDD--PDLCFLIDQVQLG-
LQCCGA----ASYQDWQWNLYFN-CSSPGV---QACSLPASCCV------------DPWE
GGASVNDQCGFGALGLDEDAA-----QRVVHLEGCGPPLLQWLRSNIRTVGCYAIVVVLV
Q----------------------GVELLLAIQLVRALTVHKGAEGIHEAARLAPIQPSGA
FSAPNVFPPLSL------------------------------AEAPPIPATCACAIHSY-
---------------------------------------------------------
>gi|157104679|ref|XP_001648520.	Aedes aegypti
------------------------------------------------------------
---------MPPYRYPT------QNFTYVSSCVK-YMIFMLNFIFW-LFGGLLIGIGFYA
FVDKWQ-ATGLIKLETVYDI-VLNISLVMIIAGGIVFVVSFAGCLGALRENTCLLKFYSL
CLLMFFLCEMAVAIVGFVFPH--KMNIVLEDSFTDKIITTYRDD--PDLQNFIDFAQQE-
FHCCGLS--NEGYLDWGKNEYFN-CSSPSV---EKCGVPYSCCIN-----------ATDI
SSGLVNIMCGYHIQQQSVAAA-----SKKIWTSGCIEIVRVWAERNLYLIAGIALGAALS
Q----------------------LFVIYLAKTLEGQID----------------------
------------------------------------------LQKSRWSS----------
---------------------------------------------------------
>gi|119120834|ref|NP_114151.3|	Homo sapiens
-----------MEEGERSPLLSQETAGQKPLSVHRPPTSGCLGPVPREDQAEAWGCSCCP
PETKHQALSGTPKKGPA------PSLSPGSSCVK-YLIFLSNFPFS-LLGLLALAIGLWG
LAVKG-----SLGSDLGGPL-PADPMLGLALGGLVVSAVSLAGYLGALCENTCLLRGFSG
GILAFLVLEAVAGALVVALWG--PLQDSLEHTLRVAIAH-YQDD--PDLRFLLDQVQLG-
LRCCGA----ASYQDWQQNLYFN-CSSPGV---QACSLPASCCI------------DPRE
DGASVNDQCGFGVLRLDADAA-----QRVVYLEGCGPPLRRWLRANLAASGGYAIAVVLL
Q----------------------GAELLLAARLLGALAARRGAAYGPGARGEDRAGPQSP
SPGAP-------------------------------------PAAKPARG----------
---------------------------------------------------------
>gi|47215343|emb|CAG12577.1|	Tetraodon nigroviridis
------------------------------------------------------------
-----------------------------------------------LVGLCVLCVGVYA
EVERQ-------KNRTLEGL-FLAPAVVLILLGLVMFTVSVVGMVGSLRDNKTLLHMFLC
VLCVLLLLQAVALTMALIFEK--KTSALFQSSIREGIKH-YYDD--LDFKNILDYVQQK-
FSCCGG----DEYKDWGVNQYHF-CNGTGP---LACGVPYTCCVR-----------HKV-
-GEVINTLCGYQTLDKARESL-----QDKIHVRGCIHAVNLWMGDNIGITVALCCAVGLP
QKVTRFPSVRLLLPGIYLPICCQLLGIILSCVFWNLLVDMSESPDMVDFK-LKKAEVNYS
ELDLAGAGWCMCLPRDGGYLPV--PASESDLDPIDIHLEKLKKQPRRTHAQLREMQQSRS
ASGLDEVDAGRKKKRDH----------------------------------------
>gi|125778304|ref|XP_001359910.	Drosophila pseudoobscura
---------------------------------------------------------MSN
HRYHHGGSYMHPRMSYP------HHFTYVSSCVK-YMIFLLNFLFW-LFGGLLLAIGVYA
FMDKLKDGNGWLRLDTVYDV-IFNISLVMIIAGCVIFVVSFAGCLGALRENTCLLKFYSM
CLLMFFIMEMTLAIICFVFPQ--YMNSFLESQFAEKIIHSYRDD--SDLQNFIDFAQQE-
FKCCGLS--NAGYQDWSKNEYFN-CSSPSV---EKCGVPYSCCIN-----------ATDI
SSGLVNIMCGYGVQEHSVAAA-----SKRIWTSGCIEIVRVWVERNLYVIAGVALGVALL
Q----------------------LFVIYLAKTLEGQID----------------------
------------------------------------------LQKSRWS-----------
---------------------------------------------------------
>gi|110758238|ref|XP_624287.2|	Apis mellifera
------------------------------------------------------------
---------MPAVRKYR------RDTSEVSCCLK-YVIFGFNVMFW-WLGLGIMAVGVWA
WTEKD----TFNNLSRLTNV-ALDPAFILILVGTVTFIIGFTGCVGALRENTCLLATYAI
FLALLLLMEMAAGVLGFIFKD--WIKSQATGGFQAFIIH-YRED--PDQQNLIDWIQEDW
LQCCGI----EGPKDWDRNNYFN-CSSSDIGSREACGVPFSCCKR-----------KPN-
-EIIKNKQCGYDVRK-PSYTG-----ERSIYERGCLRAGEEWLELNLVPVAGTVVSTMVL
Q----------------------NFEV---AKVIYEKGCIQAGEEWVERNLLAIVTGAVA
TAFAQILGICFAQNLRADIF----------------------AQKAKWH-----------
---------------------------------------------------------
>gi|149706216|ref|XP_001501708.	Equus caballus
-----------MGGRGRARFPGRRAGRAGPLAAAECPRSSCPRRLRRLPAAPGGRRRFPA
RASPGQRGSGASRCGAS------SPAARAPAAAR-LMPPGAEQNM--VISMVMVAVGVYA
RLMKH-------AEAALAYL-AVDPAIVLIVVGVLMFLLTFCGCIGSLRENICLLQTFSL
CLTIVFLLQLAAGILGFIFSD--KARGKVSEIISNAIVH-YRDD--LDLQNLIDFGQKK-
FSCCGG----ISYKDWSLNMYFN-CSEDNP-SRERCSVPYSCCLP-----------TPN-
-QAVINTMCGQGMQALEYLEA-----SKVIYTNGCIDKLVNWIHSNLFLVGGVALGLAIP
Q----------------------LVGILLSQILVNQIRDQIKLQLYNQQ-----------
------------------------------------------HQADPWY-----------
---------------------------------------------------------
>gi|126308896|ref|XP_001379839.	Monodelphis domestica
-----------MVEDERTQLLPKEAGWDEPPSLSCNHSERVLASVPKKNPAGPSGWGCLP
PGAKWKS-TLDRQGGLP------LSLNFWSSCIK-YLIFLLNFLFS-LLGLLTLVIGLWG
LEDKK-----SLGSEQLPHL-GTDPMLLFVVVGLAVSAVFLAGCVGALCENICLLWFFAG
GIFTFLILETLVGILVYALWD--QFQDVLDSAMLLAISR-YQDD--SDLRFLLNEIQLG-
LQCCGV----VSYQDWKSNLYFN-CSSPGV---QACGLPASCCI------------NPWE
NGTIINSQCGFGALRLDEATA-----QNMVHFGGCSPRLRQWMDQNSWAIRDYTLVTIVI
E----------------------GLEFLLVTKLVRDIKARKISD----------------
------------------------------------------------------------
---------------------------------------------------------
>gi|148234346|ref|NP_001085976.	Xenopus laevis
------------------------------------------------------------
--------MDASEVRYC------SRFNYI--CLK-FALIVYSTIFW-LVGAFVLAIGIYA
EVERQ-------KYKTLHGI-FLAPSIILILLGVLMFVVSFIGVLASLRDNLCLLKVFMY
TLGVCLMLELIGGVIALIFRH--QTMDLLNHNIGKGIKN-YYDD--LDFKNIMDFTQQQ-
FRCCGG----KDYLDWEQNEYHK-CSAPGP---LACGVPYTCCMR-----------NK--
-TDVMNTMCGYKAMNLERLDA-----IKFIYVRGCTDAVIIWFLDNYTIMAGVLLGILLP
Q----------------------FLGVLLCLLYVTRIEDIISEWDSSGVLLDGDSVKREI
EFSKKGCCSCY-------------------------------PGMESTA-----------
---------------------------------------------------------
>gi|74195318|dbj|BAE28380.1|	Mus musculus
MRPLPRYLAVVMPKSHCHSKNKDTAGREHPLTRNSPPTANIPCPAPWENQKGSWGCRCCP
GAKRQASGEGQASSLP---------LSTGSNCVK-YLIFLSNFLFS-LPSLLALAAGLWG
LTVKR-----SQGIGWGGPV-PTDPMLMLVLGGLVVSVVSLSGCLGAFCENSCLLHWYCG
AVLFCLALEALAGVLMVTLWK--PLQDSLKYTLHAAIIH-YWDD--PDLHFLLDQVQLG-
LQCCGA----VSYQDWQQNLYFN-CSSPGV---QACSLPASCCI------------NPQE
DGAVVNTQCGFGALGLDQNVA-----GQVVFLQGCWPALQEWLRGNTGAIGDCAVAVVMI
Q----------------------GTELLLAACLLRALAVHEAAED---------------
------------------------------------------IEAGPL------------
---------------------------------------------------------
>gi|73953740|ref|XP_853199.1|	Canis familiaris
-------MKSLRPVFSTVNRPELENRGLYGESSRITSGWSFPTGPKPGQGPAPEQLSPVS
GGQFHGDPASQKMHYYR------YSNAEVSCWYK-YLLFSYNIVFW-LAGVVFLGVGLWA
WSEKG----VLSDLTKVTRLHGIDPVVLVLMVGVVMFTLGFAGCVGALRENICLLKFFCG
TIVLIFFLELAVAVLAFLFQD--WVRDRFREFFESNIRS-YRDD--IDLQNLIDSLQKA-
NQCCGA----YGPEDWDLNVYFN-CSGASY-SREKCGVPFSCCVP-----------DPA-
-QKVVNTQCGYDVRTQLKSKW-----DESIFTKGCIQALEGWLPRNIYIVAGVFIAISLL
Q----------------------IFGIFLAKTLISDIEAVKAGHHF--------------
------------------------------------------------------------
---------------------------------------------------------
>gi|24582086|ref|NP_523487.1|	Drosophila melanogaster
------------------------------------------------------------
--------MPAAVRKFR------RETSEISCCLK-YLLFASNVILW-LSALLVLSVGIWA
WSEKG----MFRNIARLHFI-ALDPAFVLIILGGVTFLLGFMGSVGALRENTCLLGAYAI
FLSVLLIAEIGFCAVAFVLKDKGWIKDQATEGLKAFIRH-YRED--ADQQNLIDWIQEDW
LQCCGI----DGPKDWDSNNYFN-CSSIAIGSREACGVPFSCCRR-----------RPQ-
-EVIKNKQCGYDVRK-EGYPV-----DRNIHERGCLRAGEDWLEAHLISVAIGCVALLVL
Q----------------------VQNISIVVVVYFFLNL---------------------
------------------------------------------------------------
---------------------------------------------------------
