Species page : Loa loa

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Species Loa loa

Open source image (Loa loa microfilaria)

Common Name: Eye worm
Clade: III
Disease: Loa loa parasites infect human hosts by travelling from the entry site through subcutaneous tissues and causing inflammation in the skin wherever they travel. If a parasite stops in one place for a short period of time, the human host will suffer from local inflammation known as Calabar swellings. These are localized, tense, inflammatory pruritic subcutaneous edema seen in joints of extremities, lasting for 1-3 days. They represent areas of angioedema resulting from a host response to allergens released by the maturating worm and its metabolic products. Calabar swellings often occur in the wrist and ankle joints but disappear as soon as the parasite begins to move again. Parasites can also travel through and infect the eye, causing the swelling of the eye. Common symptoms include itching, joint pain, fatigue, and death
External Collaborators: Please contact to establish a collaboration.
Citations: Genomics of Loa loa, a Wolbachia-free filarial parasite of humans
NemaGene information: NemaGene gene count :15445
NemaBLAST database: BLAST vs. transcript contigs & genes
KEGG Associations: NemaPath
NCBI BioProject id: PRJNA60051
WormBase genome: Loa loa at WormBase
WormBase Parasite: Loa loa species page at WormBase ParaSite
Nembase4 species page: Loa loa species page at Nembase4 v4.0(AWS)    Copyright Statement
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The Genome Institute Washington University School of Medicine