Species page : Brugia malayi

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Species Brugia malayi

Picture Credit: Brugia malayi L3, Sinclair Stammers, Imperial College, London

Common Name: filariasis or elephantiasis
Clade: Clade III
Disease: Filarial worms infect over 100 million people in tropic regions (Wucheria bancrofti is more common than Brugia malayi). Worms, which are spread by mosquitos, reside in the human lymphatic system where they can block lymphatic drainage. Chronic infection can result in swelling and scarring of limbs and genitals.
Libraries: Library links
Available cDNAs:
Sanger ESTs:   3742 reads   1609 contigs   nucleotide link   protein link
Sequencing: Majority by Filarial Genome Network including Williams Lab at Smith College, Northampton MA and Blaxter Lab at Edinburgh University. Small sequencing project by Washington University Nematode EST Project, The Genome Institute, Washington University School of Medicine, St. Louis, MO. The complete genomic sequence for B. malayi was done by The Institute of Genomic Research (TIGR), funding by NIH-NIAID. Improved version of the genome and the annotation is available at WormBase (link)
External Collaborators: Gary Weil, Washington University School of Medicine, St. Louis, MO.
Mark Blaxter, Edinburgh University
Steve Williams, Smith College
Elodie Ghedin, TIGR
Project Contact: Makedonka Mitreva
NemaGene Gene table: NemaGene Gene table for Brugia malayi
NemaGene information: NemaGene gene count :17,989
NemaBLAST database: BLAST vs. reads grouped by library
BLAST vs. transcript contigs & genes
Codon usage table: Codon Usage table
NemFam database: NemFam search
GO Associations: GO Associations
KEGG Associations: NemaPath
Gene Expression data: Microarray data
Mass Spec data: mass spec data avaliable
HelmCoP database: HelmCoP search
WormBase genome: Brugia malayi at WormBase
WormBase Parasite: Brugia malayi species page at WormBase ParaSite
Nembase4 species page: Brugia malayi species page at Nembase4 v4.0(AWS)    Copyright Statement
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The Genome Institute Washington University School of Medicine